chr1:206940947:> Detail (hg19)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr1:206,940,947-206,947,886 |
hg38 | chr1:206,767,602-206,774,541 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.010 | renal cell carcinoma | NA | BeFree,GAD | Detail | |
0.020 | squamous cell carcinoma | Determination of IL-10 salivary concentration enabled us to distinguish patients... | BeFree,GAD,LHGDN | 25500427 | Detail |
0.080 | Cardiomyopathy, Dilated | NA | RGD | Detail | |
0.029 | Cardiovascular Diseases | NA | BeFree,GAD,LHGDN | Detail | |
0.003 | Carotid Artery Diseases | NA | LHGDN | Detail | |
0.003 | carotid stenosis | NA | BeFree,GAD | Detail | |
<0.001 | Cartilage Diseases | NA | BeFree | Detail | |
0.020 | celiac disease | NA | BeFree,GAD,LHGDN | Detail | |
0.002 | intracranial arteriosclerosis | NA | GAD | Detail | |
<0.001 | cerebral infarction | NA | BeFree | Detail | |
0.005 | brain ischemia | NA | GAD | Detail | |
0.080 | Transient ischemic attack | NA | RGD | Detail | |
0.003 | cerebral palsy | NA | BeFree,GAD | Detail | |
0.002 | Cerebrovascular Disorders | NA | GAD | Detail | |
0.005 | Malignant tumor of cervix | Interleukin-10 gene -1082 G/A polymorphism in cervical cancer and cervical intra... | BeFree | 25281063 | Detail |
0.005 | Malignant tumor of cervix | IL-10 polymorphisms play a role in cervical cancer development and that GTC hapl... | BeFree | 25412954 | Detail |
<0.001 | Cervix Diseases | NA | BeFree | Detail | |
<0.001 | Cervical dysplasia | NA | BeFree | Detail | |
0.002 | Uterine Cervical Incompetence | NA | GAD | Detail | |
0.014 | Uterine Cervical Neoplasm | NA | GAD | Detail | |
0.082 | Chagas Cardiomyopathy | NA | GAD,RGD | Detail | |
<0.001 | Developmental Disabilities | NA | BeFree | Detail | |
0.006 | Chlamydia Infections | Significant roles played by IL-10 in Chlamydia infections. | BeFree,GAD | 24398613 | Detail |
0.002 | Primary biliary cirrhosis | NA | BeFree | Detail | |
<0.001 | Cholangitis, Sclerosing | NA | BeFree | Detail | |
0.002 | chorioamnionitis | NA | GAD | Detail | |
0.003 | chorioretinitis | NA | BeFree,GAD | Detail | |
<0.001 | hemophilia B | The combination of oral delivery of bioencapsulated FIX and intravenous replacem... | BeFree | 25700434 | Detail |
0.082 | Bronchitis, Chronic | NA | GAD,RGD | Detail | |
0.006 | Churg-Strauss syndrome | NA | BeFree,GAD,LHGDN | Detail | |
0.002 | clonorchiasis | NA | GAD | Detail | |
0.222 | colitis | Furthermore, blocking inflammasome activation with caspase-1 inhibitor in vivo s... | BeFree,CTD_human,LHGDN,RGD | 24472848 | Detail |
0.222 | colitis | Predictive validity and immune cell involvement in the pathogenesis of piroxicam... | BeFree,CTD_human,LHGDN,RGD | 24797915 | Detail |
0.222 | colitis | Mice transferred with IL-10 KO cells received diets with or without food antigen... | BeFree,CTD_human,LHGDN,RGD | 25099432 | Detail |
0.222 | colitis | Mesenteric lymph node (MesLN) T cells were isolated from PAC IL-10 (-/-) mice an... | BeFree,CTD_human,LHGDN,RGD | 25112700 | Detail |
0.222 | colitis | Oral administration of B2 DNA beads significantly improved body weight, reduced ... | BeFree,CTD_human,LHGDN,RGD | 25127031 | Detail |
0.222 | colitis | PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependen... | BeFree,CTD_human,LHGDN,RGD | 25387791 | Detail |
0.222 | colitis | Serotonin (5-HT) release and serotonin reuptake transporter (5-HTT) expression h... | BeFree,CTD_human,LHGDN,RGD | 25532499 | Detail |
0.222 | colitis | SEW2871 treatment protects from colitis in IL-10(-/-) mice through reduced epith... | BeFree,CTD_human,LHGDN,RGD | 25588868 | Detail |
0.222 | colitis | Butein ameliorated colitis in IL-10(-/-) mice by regulating IL-6/STAT3 and MMP-9... | BeFree,CTD_human,LHGDN,RGD | 25593461 | Detail |
0.222 | colitis | Finally, abrogation of cellulose production reduced NC101 induction of colitis w... | BeFree,CTD_human,LHGDN,RGD | 26216423 | Detail |
0.008 | Colonic Neoplasms | NA | BeFree,GAD,LHGDN | Detail | |
0.008 | Colorectal Neoplasms | NA | BeFree,GAD | Detail | |
0.007 | common cold | NA | GAD | Detail | |
0.003 | common variable immunodeficiency | NA | BeFree,GAD | Detail | |
0.003 | Connective Tissue Diseases | NA | BeFree,GAD | Detail | |
0.002 | Constipation | NA | GAD | Detail | |
0.006 | Febrile Convulsions | NA | BeFree,GAD | Detail | |
0.003 | corneal ulcer | NA | BeFree,GAD | Detail | |
0.003 | coronary aneurysm | Association of promoter genetic variants in interleukin-10 and Kawasaki disease ... | BeFree,GAD | 24659220 | Detail |
<0.001 | craniosynostosis | We found that both clarithromycin and dexamethasone up-regulated the production ... | BeFree | 26047816 | Detail |
0.166 | Crohn Disease | Increasing evidence indicates that IL-10 plays an important role in both the ons... | BeFree,CTD_human,GAD,LHGDN | 24639111 | Detail |
0.166 | Crohn Disease | The interleukin-10 knockout (IL-10 KO) mouse is a well-established murine model ... | BeFree,CTD_human,GAD,LHGDN | 25544730 | Detail |
0.016 | cystic fibrosis | Pro-inflammatory alleles of three cytokine genotypes, IL-8, IL-10 and IL-1β, app... | BeFree,GAD,LHGDN | 24853301 | Detail |
<0.001 | cystitis | NA | BeFree | Detail | |
0.009 | Cytomegalovirus Infections | The allelic as well as genotypic frequencies of TNF-α and IL-10 did not signific... | BeFree,GAD | 25208755 | Detail |
<0.001 | Delirium | NA | BeFree | Detail | |
<0.001 | Presenile dementia | NA | BeFree | Detail | |
<0.001 | Demyelinating Diseases | NA | BeFree | Detail | |
0.004 | Dengue Fever | In the present study, the association between IL-12B, IL-10 and TNF-α gene polym... | BeFree,LHGDN | 25589894 | Detail |
<0.001 | dental caries | NA | BeFree | Detail | |
0.002 | Dental Plaque | NA | GAD | Detail | |
0.002 | Mental Depression | NA | BeFree | Detail | |
0.002 | depressive disorder | NA | BeFree | Detail | |
0.001 | dermatitis | NA | BeFree | Detail | |
0.138 | Dermatitis, Atopic | NA | BeFree,CTD_human,GAD | Detail | |
0.006 | dermatomyositis | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | scleroderma | NA | BeFree | Detail | |
0.003 | Diabetes | NA | BeFree | Detail | |
0.008 | diabetes mellitus | NA | BeFree,GAD | Detail | |
0.080 | Diabetes Mellitus, Experimental | NA | RGD | Detail | |
0.157 | Diabetes Mellitus, Insulin-Dependent | The results revealed that the DM1-preventing function was in part caused by a re... | BeFree,CTD_human,GAD,LHGDN | 25157497 | Detail |
0.157 | Diabetes Mellitus, Insulin-Dependent | Likewise, healthy individuals showed increased frequencies of both CD40(+) and I... | BeFree,CTD_human,GAD,LHGDN | 25187361 | Detail |
0.157 | Diabetes Mellitus, Insulin-Dependent | T cells secreting the cytokines IFN-γ and IL-10 in response to seven peptides kn... | BeFree,CTD_human,GAD,LHGDN | 25225671 | Detail |
0.035 | Diabetes Mellitus, Non-Insulin-Dependent | Association between interleukin 10 gene polymorphisms and risk of type 2 diabete... | BeFree,GAD | 24758873 | Detail |
0.035 | Diabetes Mellitus, Non-Insulin-Dependent | TLR3 and downstream anti-inflammatory factors (IRF-3, INF-β and IL-10) were sign... | BeFree,GAD | 24845156 | Detail |
0.035 | Diabetes Mellitus, Non-Insulin-Dependent | Our findings suggest that TGF-β1 and IL-10 polymorphisms are involved in complic... | BeFree,GAD | 26064986 | Detail |
0.006 | Diabetic Nephropathy | Our results indicate that 11 genetic variants within or near VEGFA, CCR5, CCL2, ... | BeFree,GAD | 25280384 | Detail |
0.006 | Diabetic Nephropathy | Interleukin-10-1082A/G polymorphism and diabetic nephropathy: a meta-analysis. | BeFree,GAD | 25806430 | Detail |
<0.001 | diabetic retinopathy | Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codo... | BeFree | 26064986 | Detail |
0.006 | diarrhea | NA | BeFree,GAD | Detail | |
0.127 | drug allergy | NA | CTD_human,GAD | Detail | |
0.005 | Duodenal Diseases | NA | GAD | Detail | |
0.003 | duodenal ulcer | NA | BeFree,GAD | Detail | |
<0.001 | Shigella Infections | NA | BeFree | Detail | |
0.003 | eclampsia | Meta-analysis of associations between interleukin-10 polymorphisms and susceptib... | BeFree,GAD | 25305663 | Detail |
0.010 | Eczema | NA | BeFree,GAD | Detail | |
<0.001 | Filarial Elephantiases | NA | BeFree | Detail | |
<0.001 | encephalitis | NA | BeFree | Detail | |
<0.001 | tick-borne encephalitis | Increased concentration of interferon lambda-3, interferon beta and interleukin-... | BeFree | 25461389 | Detail |
0.083 | Experimental Autoimmune Encephalomyelitis | By using IL-10 reporter mice, we found that plasmablasts in the draining lymph n... | BeFree,RGD | 25484301 | Detail |
<0.001 | Bacterial Endocarditis | In this study, 14 single nucleotide variants (SNVs) in genes coding for interleu... | BeFree | 25299518 | Detail |
0.030 | endometriosis | NA | BeFree,GAD,LHGDN | Detail | |
0.120 | Entamoebiasis | NA | CTD_human | Detail | |
<0.001 | Enteritis | NA | BeFree | Detail | |
0.122 | Enterocolitis | Piroxicam administration is a method for induction of enterocolitis in interleuk... | BeFree,CTD_human | 24797915 | Detail |
0.004 | Eosinophilia | We found that both clarithromycin and dexamethasone up-regulated the production ... | BeFree,GAD | 26047816 | Detail |
0.003 | epidermodysplasia verruciformis | NA | BeFree,GAD | Detail | |
<0.001 | Epithelial hyperplasia | NA | BeFree | Detail | |
0.002 | Equine Infectious Anemia | NA | GAD | Detail | |
0.003 | erythema nodosum | NA | BeFree,GAD | Detail | |
0.003 | Escherichia coli Infections | NA | BeFree,GAD | Detail | |
<0.001 | Esophageal Achalasia | NA | BeFree | Detail | |
0.010 | Esophageal Neoplasms | By contrast, the percentage of peripheral IL‑10‑producing Bregs (B10s) significa... | BeFree,GAD | 24969402 | Detail |
0.003 | esophagitis | NA | BeFree,GAD | Detail | |
<0.001 | peptic esophagitis | NA | BeFree | Detail | |
<0.001 | Exanthema | NA | BeFree | Detail | |
<0.001 | Eye Infections | NA | BeFree | Detail | |
0.002 | Eye Infections, Bacterial | NA | GAD | Detail | |
0.001 | Fatigue | NA | BeFree | Detail | |
0.002 | chronic fatigue syndrome | NA | GAD | Detail | |
0.085 | Fatty Liver | NA | GAD,LHGDN,RGD | Detail | |
<0.001 | fetal alcohol syndrome | NA | BeFree | Detail | |
0.002 | Fetal Death | NA | GAD | Detail | |
0.002 | Fetal Diseases | NA | GAD | Detail | |
0.002 | Fetal Membranes, Premature Rupture | NA | GAD | Detail | |
0.005 | Fever | NA | GAD | Detail | |
<0.001 | breast fibrocystic disease | NA | BeFree | Detail | |
0.003 | fibromyalgia | NA | LHGDN | Detail | |
0.013 | Fibrosis | NA | GAD,LHGDN | Detail | |
<0.001 | filariasis | NA | BeFree | Detail | |
<0.001 | pathologic fistula | NA | BeFree | Detail | |
<0.001 | folliculitis | NA | BeFree | Detail | |
0.002 | food allergy | NA | GAD | Detail | |
<0.001 | Fowlpox | NA | BeFree | Detail | |
0.003 | Gall Bladder Diseases | NA | BeFree,GAD | Detail | |
0.016 | gastritis | FOXP3 mRNA levels were correlated positively with TGF-β1 and IL-10 mRNA levels i... | BeFree,GAD,LHGDN | 24121150 | Detail |
0.010 | Gastritis, Atrophic | NA | BeFree,GAD | Detail | |
0.005 | gastroenteritis | NA | GAD | Detail | |
0.002 | gastroesophageal reflux disease | NA | GAD | Detail | |
0.002 | Gingival Diseases | NA | BeFree | Detail | |
0.006 | gingivitis | NA | BeFree,GAD | Detail | |
<0.001 | glioblastoma | NA | BeFree | Detail | |
0.003 | Glioma | NA | BeFree | Detail | |
0.126 | glomerulonephritis | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
0.019 | IgA glomerulonephritis | NA | BeFree,GAD,LHGDN | Detail | |
0.011 | Focal glomerulosclerosis | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | gonorrhea | NA | BeFree | Detail | |
0.049 | Graft-vs-Host Disease | NA | BeFree,GAD,LHGDN | Detail | |
0.007 | Graves Disease | NA | BeFree,GAD | Detail | |
0.005 | Guillain-Barre syndrome | NA | BeFree,GAD | Detail | |
0.002 | Hand Dermatoses | NA | GAD | Detail | |
<0.001 | Hay fever | NA | BeFree | Detail | |
0.002 | Head and Neck Neoplasms | NA | GAD | Detail | |
0.086 | Heart failure | NA | BeFree,GAD,LHGDN,RGD | Detail | |
<0.001 | congestive heart failure | NA | BeFree | Detail | |
0.002 | heart valve disease | NA | GAD | Detail | |
0.120 | Heat Stroke | NA | CTD_human | Detail | |
0.001 | Helminthiasis | NA | BeFree | Detail | |
<0.001 | hemochromatosis | NA | BeFree | Detail | |
0.011 | Hemophilia A | NA | BeFree,GAD | Detail | |
<0.001 | Hemorrhagic Fever, Crimean | NA | BeFree | Detail | |
0.003 | Severe Dengue | The overall findings of the study support the correlation of high-producer TNF-α... | BeFree,GAD | 25589894 | Detail |
0.004 | hepatitis | NA | BeFree,LHGDN | Detail | |
<0.001 | hepatitis A | NA | BeFree | Detail | |
0.050 | hepatitis B | In addition, expression levels of anti-inflammatory cytokine IL-10 was down-regu... | BeFree,GAD,LHGDN | 24618716 | Detail |
0.050 | hepatitis B | Association between IL-10 gene promoter polymorphism and hepatitis B viral infec... | BeFree,GAD,LHGDN | 24838671 | Detail |
0.050 | hepatitis B | Association of interleukin-10 with hepatitis B virus (HBV) mediated disease prog... | BeFree,GAD,LHGDN | 25027084 | Detail |
0.050 | hepatitis B | Circulating CD56dim natural killer cells and CD56+ T cells that produce interfer... | BeFree,GAD,LHGDN | 25186004 | Detail |
0.050 | hepatitis B | Association of the IFNAR1-17470 and IL-10-592 cytokine variants with susceptibil... | BeFree,GAD,LHGDN | 25501140 | Detail |
0.050 | hepatitis B | The start of immune-clearance phase, age at HBeAg seroconversion, and serum IL-1... | BeFree,GAD,LHGDN | 25505294 | Detail |
0.050 | hepatitis B | Influence of IL10 gene polymorphisms on the severity of liver fibrosis and susce... | BeFree,GAD,LHGDN | 25514046 | Detail |
0.050 | hepatitis B | The presence of low producing IL-10-1082A and -592A alleles and their containing... | BeFree,GAD,LHGDN | 25542814 | Detail |
0.050 | hepatitis B | A -819 C/T polymorphism in the interleukin-10 promoter is associated with persis... | BeFree,GAD,LHGDN | 25583543 | Detail |
0.003 | Hepatitis, Alcoholic | NA | BeFree,GAD | Detail | |
0.001 | Hepatitis, Chronic | In addition, the OR of the patients with CHB having the IL-10-592 C/C variant de... | BeFree | 25501140 | Detail |
0.002 | Hepatitis, Toxic | NA | GAD | Detail | |
0.002 | Hepatitis, Viral, Human | NA | GAD | Detail | |
0.042 | hepatitis C | Although we found a possible association between IL-10 promoter polymorphisms an... | BeFree,GAD,LHGDN | 25119896 | Detail |
0.042 | hepatitis C | We investigated the association between hepatitis C virus (HCV) genotypes and ho... | BeFree,GAD,LHGDN | 25193024 | Detail |
0.042 | hepatitis C | Relationships between interleukin-12B and interleukin-10 gene polymorphisms and ... | BeFree,GAD,LHGDN | 25613737 | Detail |
0.042 | hepatitis C | This study investigated genetic variability in the IL-10 gene promoter between p... | BeFree,GAD,LHGDN | 25797191 | Detail |
0.120 | Hepatolenticular Degeneration | NA | BeFree,CTD_human | Detail | |
<0.001 | Herpes NOS | NA | BeFree | Detail | |
0.002 | Herpes Simplex Infections | NA | GAD | Detail | |
0.010 | Herpes zoster disease | NA | BeFree,GAD,LHGDN | Detail | |
0.003 | Herpesviridae Infections | NA | BeFree,GAD | Detail | |
0.176 | HIV Infections | Reduced levels of let-7 miRNAs have been linked to higher levels of IL-10, again... | BeFree,CTD_human,GAD | 25023625 | Detail |
0.176 | HIV Infections | Influence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV... | BeFree,CTD_human,GAD | 25542814 | Detail |
0.176 | HIV Infections | Polymorphisms in the IFNγ, IL-10, and TGFβ genes may be associated with HIV-1 in... | BeFree,CTD_human,GAD | 25802474 | Detail |
0.025 | Hodgkin Disease | This study was undertaken to investigate the possible association of genetic pol... | BeFree,GAD,LHGDN | 25613737 | Detail |
0.006 | HTLV-I Infections | NA | BeFree,GAD | Detail | |
<0.001 | Huntington disease | This study was undertaken to investigate the possible association of genetic pol... | BeFree | 25613737 | Detail |
0.200 | Hyperalgesia | NA | CTD_human,RGD | Detail | |
<0.001 | Hypercholesterolemia, Familial | NA | BeFree | Detail | |
0.003 | hyperglycemia | Distinct role of FoxO1 in M-CSF- and GM-CSF-differentiated macrophages contribut... | BeFree,GAD | 25420919 | Detail |
0.002 | Hyperparathyroidism, Secondary | NA | GAD | Detail | |
0.009 | Hypersensitivity | NA | GAD | Detail | |
0.122 | Immediate hypersensitivity | NA | CTD_human,GAD | Detail | |
0.088 | Hypertensive disease | Hypertension was associated with the CC genotype and C allele for IL-10 -592C/A ... | BeFree,GAD,LHGDN,RGD | 26064986 | Detail |
<0.001 | ileitis | NA | BeFree | Detail | |
<0.001 | Immunologic Deficiency Syndromes | NA | BeFree | Detail | |
0.001 | Immune System Diseases | Targeting IL-10 in auto-immune diseases. | BeFree | 24639111 | Detail |
0.001 | Immune System Diseases | Here we generated the IL10/Nox1dKO mouse model which combines immune dysfunction... | BeFree | 25014110 | Detail |
0.003 | infectious mononucleosis | NA | BeFree,GAD | Detail | |
0.002 | Female infertility | NA | GAD | Detail | |
0.273 | Inflammation | NA | CTD_human,GAD,LHGDN,RGD | Detail | |
0.163 | Inflammatory Bowel Diseases | In this study, we investigated the role of inflammasome activation in the develo... | BeFree,CTD_human,GAD,LHGDN | 24472848 | Detail |
0.163 | Inflammatory Bowel Diseases | Very early-onset inflammatory bowel disease (IBD) in infancy is a different dise... | BeFree,CTD_human,GAD,LHGDN | 24785691 | Detail |
0.163 | Inflammatory Bowel Diseases | In conclusion, reference drugs with known efficacy in severe inflammatory bowel ... | BeFree,CTD_human,GAD,LHGDN | 24797915 | Detail |
0.163 | Inflammatory Bowel Diseases | Novel de novo mutations of the interleukin-10 receptor gene lead to infantile on... | BeFree,CTD_human,GAD,LHGDN | 24813381 | Detail |
0.163 | Inflammatory Bowel Diseases | The associations in IL10 and IL18R1 are shared with inflammatory bowel disease, ... | BeFree,CTD_human,GAD,LHGDN | 25200001 | Detail |
0.163 | Inflammatory Bowel Diseases | The effect of turmeric (Curcuma longa) extract on the functionality of the solut... | BeFree,CTD_human,GAD,LHGDN | 25314644 | Detail |
0.163 | Inflammatory Bowel Diseases | Human adipose-derived stem cells attenuate inflammatory bowel disease in IL-10 k... | BeFree,CTD_human,GAD,LHGDN | 25544730 | Detail |
0.001 | influenza | NA | BeFree | Detail | |
0.002 | Insulin resistance | NA | GAD | Detail | |
<0.001 | Intestinal Diseases | NA | BeFree | Detail | |
0.080 | intestinal obstruction | NA | RGD | Detail | |
0.133 | irritable bowel syndrome | In this study, we first reproduced the recovery-recurrence periods observed in I... | BeFree,CTD_human,GAD | 24732667 | Detail |
0.004 | ischemia | NA | BeFree,LHGDN | Detail | |
<0.001 | arthropathy | NA | BeFree | Detail | |
0.017 | Kidney Diseases | Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codo... | BeFree,GAD | 26064986 | Detail |
0.042 | hepatitis C | Single-nucleotide polymorphisms (SNPs) in the IL-10 gene (-1082 [rs1800896], -81... | BeFree | 23880623 | Detail |
0.006 | Kidney Failure, Acute | NA | BeFree,GAD | Detail | |
0.029 | Kidney Failure, Chronic | NA | BeFree,GAD,LHGDN | Detail | |
0.007 | Kidney Neoplasm | NA | GAD | Detail | |
0.002 | Premature Obstetric Labor | NA | GAD | Detail | |
0.003 | Lambert-Eaton myasthenic syndrome | NA | BeFree,LHGDN | Detail | |
0.126 | leishmaniasis | The redirection of the immune response elicited against the LiPABP family (from ... | BeFree,CTD_human,LHGDN | 25955652 | Detail |
0.124 | Leishmaniasis, Cutaneous | NA | BeFree,CTD_human,GAD | Detail | |
0.125 | Leishmaniasis, Visceral | IL10 Variant g.5311A Is Associated with Visceral Leishmaniasis in Indian Populat... | BeFree,CTD_human,LHGDN | 25941808 | Detail |
0.015 | leprosy | Association of TNF-α-(308(GG)), IL-10(-819(TT)), IL-10(-1082(GG)) and IL-1R1(+19... | BeFree,GAD | 25697140 | Detail |
<0.001 | Leprosy, Lepromatous | NA | BeFree | Detail | |
0.002 | leptospirosis | NA | GAD | Detail | |
0.009 | leukemia | NA | BeFree,GAD,LHGDN | Detail | |
0.013 | chronic lymphocytic leukemia | IPI-145 potently inhibits the CD40L/IL-2/IL-10 induced proliferation of CLL cell... | BeFree,GAD | 25917267 | Detail |
0.003 | lymphoid leukemia | NA | LHGDN | Detail | |
0.002 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
0.003 | Leukemia, Lymphocytic, Acute, L1 | NA | BeFree,GAD | Detail | |
0.005 | Leukemia, Myelocytic, Acute | Herein, we applied a novel DC-based vaccine (i.e., DC loaded with leukemia antig... | BeFree,GAD | 25319656 | Detail |
0.005 | Leukemia, Myelocytic, Acute | Interleukin-10 polymorphisms associated with susceptibility to acute myeloid leu... | BeFree,GAD | 25730030 | Detail |
0.001 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
<0.001 | Leukemia, Myelomonocytic, Chronic | NA | BeFree | Detail | |
<0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
<0.001 | Leukemia, T-Cell | NA | BeFree | Detail | |
0.121 | Adult T-Cell Lymphoma/Leukemia | NA | BeFree,CTD_human | Detail | |
0.010 | liver cirrhosis | Moreover, the IL-10 protein and mRNA levels in peripheral blood mono nuclear cel... | BeFree,GAD,LHGDN | 25027084 | Detail |
0.010 | liver cirrhosis | Influence of IL10 gene polymorphisms on the severity of liver fibrosis and susce... | BeFree,GAD,LHGDN | 25514046 | Detail |
<0.001 | Liver Cirrhosis, Alcoholic | Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis i... | BeFree | 24835349 | Detail |
0.005 | Biliary cirrhosis | NA | GAD | Detail | |
0.200 | Liver Cirrhosis, Experimental | NA | CTD_human,RGD | Detail | |
0.011 | Liver diseases | NA | BeFree,GAD,LHGDN | Detail | |
0.016 | Alcoholic Liver Diseases | NA | BeFree,GAD | Detail | |
0.013 | Liver neoplasms | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | long QT syndrome | NA | BeFree | Detail | |
0.083 | Lung diseases | Pro-inflammatory alleles of three cytokine genotypes, IL-8, IL-10 and IL-1β, app... | BeFree,GAD,RGD | 24853301 | Detail |
0.005 | Lung Diseases, Fungal | NA | GAD | Detail | |
0.021 | Chronic Obstructive Airway Disease | Analysis of mRNA transcripts of unstimulated lung CD4+ T cell among all subjects... | BeFree,GAD,LHGDN | 24805101 | Detail |
0.021 | Chronic Obstructive Airway Disease | IL-10 disrupts the Brd4-docking sites to inhibit LPS-induced CXCL8 and TNF-α exp... | BeFree,GAD,LHGDN | 26044852 | Detail |
0.137 | Lung Neoplasms | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
0.010 | Lupus Vulgaris | Stat3 promotes IL-10 expression in lupus T cells through trans-activation and ch... | BeFree,GAD | 25187566 | Detail |
0.012 | Lupus Erythematosus, Discoid | Stat3 promotes IL-10 expression in lupus T cells through trans-activation and ch... | BeFree,GAD | 25187566 | Detail |
0.237 | Lupus Erythematosus, Systemic | Increasing evidence indicates that IL-10 plays an important role in both the ons... | BeFree,CTD_human,GAD,LHGDN | 24639111 | Detail |
0.237 | Lupus Erythematosus, Systemic | Stat3 promotes IL-10 expression in lupus T cells through trans-activation and ch... | BeFree,CTD_human,GAD,LHGDN | 25187566 | Detail |
0.237 | Lupus Erythematosus, Systemic | STAT4 and IL10 confirm their association with SLE. | BeFree,CTD_human,GAD,LHGDN | 25369137 | Detail |
0.237 | Lupus Erythematosus, Systemic | Lack of association between interleukin-10, transforming growth factor-beta gene... | BeFree,CTD_human,GAD,LHGDN | 25633651 | Detail |
0.237 | Lupus Erythematosus, Systemic | The cytokines IL-6 and IL-10 are produced by cells of the adaptive and innate ar... | BeFree,CTD_human,GAD,LHGDN | 25794663 | Detail |
0.007 | lupus nephritis | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Lyme disease | NA | BeFree | Detail | |
0.005 | lymphadenitis | NA | BeFree,GAD | Detail | |
<0.001 | Lymphatic Diseases | NA | BeFree | Detail | |
0.002 | Lymphatic Metastasis | NA | GAD | Detail | |
0.002 | Lymphocytosis | NA | GAD | Detail | |
<0.001 | Lymphohistiocytosis, Hemophagocytic | NA | BeFree | Detail | |
0.024 | lymphoma | The interleukin-10-1082A>G polymorphism and lymphoma risk: a meta-analysis. | BeFree,GAD,LHGDN | 25171480 | Detail |
0.008 | Lymphoma, Follicular | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | reticulosarcoma | NA | BeFree | Detail | |
0.048 | Lymphoma, Non-Hodgkin | Analysis of interleukin-10 promoter single nucleotide polymorphisms and risk of ... | BeFree,GAD,LHGDN | 24684230 | Detail |
<0.001 | lymphopenia | NA | BeFree | Detail | |
0.011 | Lymphoproliferative Disorders | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Waldenstrom Macroglobulinemia | NA | BeFree | Detail | |
<0.001 | Macular Edema, Cystoid | In addition, the aqueous humor levels of IL-10 and IL-12 decreased with increasi... | BeFree | 25923230 | Detail |
0.010 | malaria | IL10A genotypic association with decreased IL-10 circulating levels in malaria i... | BeFree,GAD | 25627396 | Detail |
0.010 | malaria | Proinflammatory responses and higher IL-10 production by T cells correlate with ... | BeFree,GAD | 25725110 | Detail |
0.001 | Malaria, Cerebral | NA | BeFree | Detail | |
0.016 | Malaria, Falciparum | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Malaria, Vivax | NA | BeFree | Detail | |
0.025 | Malignant neoplasm of stomach | The allele flip observed in IL-10 and gastric cancer appears to reflect allelic ... | BeFree,GAD | 24782608 | Detail |
0.025 | Malignant neoplasm of stomach | Based on 40 studies and 18950 participants, we found the variant IL-10 -1082G al... | BeFree,GAD | 25091209 | Detail |
0.025 | Malignant neoplasm of stomach | Effects of interleukin-10 polymorphisms and smoking on the risk of gastric cance... | BeFree,GAD | 25189915 | Detail |
0.025 | Malignant neoplasm of stomach | Interleukin-10 gene -592C>A polymorphism and susceptibility to gastric cancer. | BeFree,GAD | 25366786 | Detail |
0.025 | Malignant neoplasm of stomach | Clinical study on gastric cancer susceptibility genes IL-10-1082 and TNF-α. | BeFree,GAD | 25526211 | Detail |
0.002 | Animal Mammary Neoplasms | NA | GAD | Detail | |
0.120 | Mammary Neoplasms, Experimental | NA | CTD_human | Detail | |
<0.001 | paroxysmal nocturnal hemoglobinuria | NA | BeFree | Detail | |
<0.001 | measles | NA | BeFree | Detail | |
0.038 | melanoma | Role of IL-10 and TGF-β in melanoma. | BeFree,GAD,LHGDN | 25565012 | Detail |
0.038 | melanoma | We discovered novel associations of IL10 with melanoma survival at 1q32.1, sugge... | BeFree,GAD,LHGDN | 25604082 | Detail |
<0.001 | melioidosis | NA | BeFree | Detail | |
0.001 | meningitis | There was an increased serum IFNβ and a tendency for increased serum IL-10 in me... | BeFree | 25461389 | Detail |
0.008 | Meningococcal Infections | NA | BeFree,GAD | Detail | |
<0.001 | Meningococcemia | IL-10 immunodepletion from meningococcal sepsis plasma induces extensive changes... | BeFree | 25233959 | Detail |
<0.001 | meningoencephalitis | IL-10, IFNβ and IFNλ3 were up-regulated in csf, with IFNλ3 level higher in patie... | BeFree | 25461389 | Detail |
<0.001 | Metabolic Diseases | Adoptive transfer of B-1a cells into HFD-fed B cell-deficient mice rapidly impro... | BeFree | 25249575 | Detail |
0.015 | Metaplasia | NA | GAD,LHGDN | Detail | |
0.001 | mitral valve stenosis | NA | BeFree | Detail | |
<0.001 | mixed connective tissue disease | Present findings indicate that IL-10 gene variants may be considered as genetic ... | BeFree | 25159155 | Detail |
0.013 | Mouth Neoplasms | NA | GAD,LHGDN | Detail | |
<0.001 | Moyamoya disease | NA | BeFree | Detail | |
0.016 | Mucocutaneous Lymph Node Syndrome | Association of promoter genetic variants in interleukin-10 and Kawasaki disease ... | BeFree,GAD,LHGDN | 24659220 | Detail |
0.010 | multiple myeloma | NA | BeFree,GAD | Detail | |
0.127 | Multiple Organ Failure | NA | CTD_human,GAD | Detail | |
0.050 | multiple sclerosis | Increasing evidence indicates that IL-10 plays an important role in both the ons... | BeFree,GAD,LHGDN | 24639111 | Detail |
0.050 | multiple sclerosis | We assessed the relationship of stimulated PBMC-produced IFN-γ, TNF-α, IL-4 and ... | BeFree,GAD,LHGDN | 24790215 | Detail |
0.050 | multiple sclerosis | Seeking balance: Potentiation and inhibition of multiple sclerosis autoimmune re... | BeFree,GAD,LHGDN | 25794663 | Detail |
<0.001 | muscular atrophy | Grape seed extract prevents skeletal muscle wasting in interleukin 10 knockout m... | BeFree | 24884473 | Detail |
<0.001 | muscular dystrophy | NA | BeFree | Detail | |
0.002 | Musculoskeletal Diseases | NA | GAD | Detail | |
0.012 | myasthenia gravis | NA | BeFree,GAD,LHGDN | Detail | |
0.004 | Mycobacterium Infections | NA | BeFree,GAD | Detail | |
0.002 | Mycoses | Gram-positive bacterial and fungal infections did not cause a marked increase in... | BeFree | 25526183 | Detail |
<0.001 | mycosis fungoides | NA | BeFree | Detail | |
0.002 | Myelodysplasia | NA | GAD | Detail | |
0.147 | myocardial infarction | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
0.080 | Myocardial Reperfusion Injury | NA | RGD | Detail | |
0.081 | myocarditis | NA | BeFree,RGD | Detail | |
0.003 | Myoclonus | NA | LHGDN | Detail | |
<0.001 | Nasal Polyps | NA | BeFree | Detail | |
0.005 | Nasopharyngeal Neoplasms | NA | GAD | Detail | |
0.007 | Neoplasm Invasiveness | NA | GAD | Detail | |
0.008 | Neoplasm Metastasis | These results suggest that tested SNPs associated with differential production o... | BeFree,GAD | 26753456 | Detail |
0.005 | Neoplasm Recurrence, Local | NA | GAD | Detail | |
0.002 | Pathologic Neovascularization | NA | GAD | Detail | |
<0.001 | nervous system disorder | NA | BeFree | Detail | |
0.081 | Neuralgia | NA | BeFree,RGD | Detail | |
0.003 | neutropenia | NA | LHGDN | Detail | |
0.093 | obesity | The expression of LEP, LEPR, IGF1 and IL10 in obesity and the relationship with ... | BeFree,GAD,RGD | 24690978 | Detail |
0.093 | obesity | B-1a cells are reduced in frequency in obese high-fat diet (HFD)-fed mice, and E... | BeFree,GAD,RGD | 25249575 | Detail |
0.002 | Dermatitis, Occupational | NA | GAD | Detail | |
0.005 | Occupational Diseases | NA | GAD | Detail | |
<0.001 | onchocerciasis | NA | BeFree | Detail | |
0.002 | Ophthalmia, Sympathetic | NA | GAD | Detail | |
<0.001 | orbit (eye disorders) | NA | BeFree | Detail | |
0.008 | Degenerative polyarthritis | Similarly, the TNFα -1031 and -863 minor alleles were associated with an increas... | BeFree,GAD | 25252624 | Detail |
0.003 | osteoporosis | NA | BeFree,GAD | Detail | |
<0.001 | Ear Inflammation | NA | BeFree | Detail | |
0.088 | otitis media | NA | BeFree,GAD,LHGDN,RGD | Detail | |
0.004 | ovarian carcinoma | NA | BeFree | Detail | |
0.096 | pancreatitis | NA | BeFree,GAD,LHGDN,RGD | Detail | |
<0.001 | panuveitis | NA | BeFree | Detail | |
0.006 | paracoccidioidomycosis | NA | BeFree,GAD,LHGDN | Detail | |
0.005 | tropical spastic paraparesis | High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-... | BeFree,GAD | 25833232 | Detail |
<0.001 | Parasitic Diseases | NA | BeFree | Detail | |
<0.001 | Paratuberculosis | Contrary to this, TNF-α levels were unchanged upon MAP stimulation regardless of... | BeFree | 25335775 | Detail |
0.007 | Parkinson disease | Interleukin-10-1082A/G and -592C/A polymorphisms with risk of Parkinson's diseas... | BeFree,GAD | 24397502 | Detail |
0.002 | Pelvic Pain | NA | GAD | Detail | |
0.010 | pemphigus | NA | BeFree,GAD | Detail | |
0.003 | pemphigus vulgaris | NA | BeFree,GAD | Detail | |
<0.001 | Allergy to penicillin | NA | BeFree | Detail | |
0.008 | Peptic Ulcer | NA | BeFree,GAD | Detail | |
0.002 | polyarteritis nodosa | NA | GAD | Detail | |
0.017 | Periodontal Diseases | NA | BeFree,GAD,LHGDN | Detail | |
0.002 | Periodontal Pocket | NA | GAD | Detail | |
0.110 | periodontitis | NA | BeFree,GAD,RGD | Detail | |
0.012 | Periodontitis, Juvenile | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Peripheral neuropathy | NA | BeFree | Detail | |
<0.001 | peritonitis | NA | BeFree | Detail | |
0.002 | Picornaviridae Infections | NA | GAD | Detail | |
<0.001 | Pituitary Diseases | NA | BeFree | Detail | |
<0.001 | Pleural effusion disorder | NA | BeFree | Detail | |
0.120 | pleurisy | NA | CTD_human | Detail | |
0.004 | Pneumococcal Infections | NA | BeFree,LHGDN | Detail | |
0.014 | pneumonia | Associations of three well-characterized polymorphisms in the IL-6 and IL-10 gen... | BeFree,GAD,LHGDN | 25708204 | Detail |
0.014 | pneumonia | Interestingly, we observed that all BI patients with high frequency of IL-10(+) ... | BeFree,GAD,LHGDN | 26364142 | Detail |
0.006 | polycystic ovary syndrome | The studies involved the following polymorphisms: TNF-α -308G > A, TNF-α -805C>T... | BeFree,GAD | 25690158 | Detail |
<0.001 | Adenomatous Polyposis Coli | NA | BeFree | Detail | |
0.001 | Post-kala-azar dermal leishmaniasis | NA | BeFree | Detail | |
0.007 | Postoperative Complications | NA | GAD | Detail | |
0.027 | pre-eclampsia | NA | GAD,LHGDN | Detail | |
0.010 | Precancerous Conditions | NA | BeFree,GAD | Detail | |
0.006 | Pregnancy Complications | NA | BeFree,GAD,LHGDN | Detail | |
0.002 | Pregnancy Complications, Hematologic | NA | GAD | Detail | |
0.002 | Pregnancy Complications, Infectious | NA | GAD | Detail | |
<0.001 | ectopic pregnancy | NA | BeFree | Detail | |
0.002 | Preleukemia | NA | GAD | Detail | |
0.123 | Prostatic Neoplasms | NA | CTD_human,LHGDN | Detail | |
0.205 | prostatitis | NA | CTD_human,GAD,RGD | Detail | |
0.002 | Pseudomonas Infections | NA | GAD | Detail | |
0.036 | psoriasis | Increasing evidence indicates that IL-10 plays an important role in both the ons... | BeFree,GAD,LHGDN | 24639111 | Detail |
0.036 | psoriasis | Psoriasis-specific genes were important regulators of glucose and lipid metaboli... | BeFree,GAD,LHGDN | 25009230 | Detail |
0.036 | psoriasis | Novel mutations in IL-10 promoter region -377 (C>T), -150 (C>A) and their associ... | BeFree,GAD,LHGDN | 25735363 | Detail |
<0.001 | Psychotic Disorders | NA | BeFree | Detail | |
0.002 | Puerperal Disorders | NA | GAD | Detail | |
0.003 | pulmonary alveolar proteinosis | NA | BeFree,LHGDN | Detail | |
<0.001 | pulmonary emphysema | Analysis of mRNA transcripts of unstimulated lung CD4+ T cell among all subjects... | BeFree | 24805101 | Detail |
0.004 | pulmonary fibrosis | NA | BeFree,GAD | Detail | |
0.005 | Q fever | NA | BeFree,GAD | Detail | |
0.004 | kidney failure | NA | BeFree,GAD | Detail | |
0.208 | Reperfusion Injury | NA | CTD_human,GAD,LHGDN,RGD | Detail | |
<0.001 | Respiration Disorders | NA | BeFree | Detail | |
0.005 | Respiratory Distress Syndrome, Newborn | NA | BeFree,GAD | Detail | |
0.006 | Respiratory Distress Syndrome, Adult | NA | BeFree,GAD | Detail | |
0.003 | Respiratory Insufficiency | NA | LHGDN | Detail | |
0.006 | Respiratory Syncytial Virus Infections | NA | BeFree,GAD | Detail | |
0.006 | Respiratory Tract Infections | NA | BeFree,GAD,LHGDN | Detail | |
0.005 | retinal artery occlusion | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | retinal detachment | NA | BeFree | Detail | |
<0.001 | Retinal Necrosis Syndrome, Acute | NA | BeFree | Detail | |
0.002 | retinal vein occlusion | NA | GAD | Detail | |
<0.001 | rheumatic fever | NA | BeFree | Detail | |
0.006 | rheumatic heart disease | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Rheumatoid Nodule | NA | BeFree | Detail | |
0.002 | Rhinitis, Allergic, Perennial | NA | GAD | Detail | |
<0.001 | Salivary Gland Diseases | NA | BeFree | Detail | |
0.008 | sarcoidosis | NA | BeFree,GAD | Detail | |
0.005 | schistosomiasis | Association of SNP (-G1082A) IL-10 with increase in severity of periportal fibro... | BeFree,LHGDN | 25079344 | Detail |
0.003 | Schistosomiasis japonica | NA | BeFree,LHGDN | Detail | |
0.010 | Schistosomiasis mansoni | NA | BeFree,GAD,LHGDN | Detail | |
0.028 | schizophrenia | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | paranoid schizophrenia | NA | BeFree | Detail | |
0.021 | systemic scleroderma | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Seizures | NA | BeFree | Detail | |
<0.001 | seminoma | NA | BeFree | Detail | |
0.010 | Septicemia | Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis ... | BeFree | 25348624 | Detail |
0.010 | Septicemia | Association between interleukin-10 polymorphisms and sepsis: a meta-analysis. | BeFree | 25497741 | Detail |
<0.001 | Sezary syndrome | NA | BeFree | Detail | |
0.080 | Shock, Hemorrhagic | NA | RGD | Detail | |
0.008 | Septic Shock | NA | LHGDN | Detail | |
<0.001 | sialadenitis | NA | BeFree | Detail | |
<0.001 | Sickle Cell Trait | NA | BeFree | Detail | |
<0.001 | silicosis | NA | BeFree | Detail | |
0.002 | sinusitis | NA | GAD | Detail | |
0.005 | Dermatologic disorders | NA | BeFree,GAD | Detail | |
0.017 | Skin Neoplasms | NA | GAD | Detail | |
0.002 | Skin Ulcer | NA | GAD | Detail | |
<0.001 | smallpox | NA | BeFree | Detail | |
0.006 | Spinal Cord Diseases | High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-... | BeFree,GAD,LHGDN | 25833232 | Detail |
0.004 | ankylosing spondylitis | Whole body hyperthermia treatment increases interleukin 10 and toll-like recepto... | BeFree,GAD | 25256892 | Detail |
0.080 | Staphylococcal Infections | NA | RGD | Detail | |
0.002 | Stomach Diseases | NA | GAD | Detail | |
0.072 | Stomach Neoplasms | NA | GAD,LHGDN | Detail | |
0.003 | gastric ulcer | NA | BeFree,GAD | Detail | |
0.005 | aphthous stomatitis | NA | GAD | Detail | |
0.003 | Streptococcal Infections | NA | BeFree,GAD | Detail | |
0.084 | Cerebrovascular accident | NA | BeFree,GAD,RGD | Detail | |
0.005 | subacute sclerosing panencephalitis | NA | BeFree,GAD,LHGDN | Detail | |
0.017 | sudden infant death syndrome | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | synovitis | NA | BeFree | Detail | |
0.001 | tetanus | NA | BeFree | Detail | |
0.002 | Thoracic Neoplasms | NA | GAD | Detail | |
0.002 | Thromboembolism | NA | GAD | Detail | |
0.005 | thymoma | NA | GAD | Detail | |
0.002 | Thyroid Neoplasm | NA | GAD | Detail | |
<0.001 | thyroiditis | NA | BeFree | Detail | |
0.080 | thyrotoxicosis | NA | RGD | Detail | |
<0.001 | toxoplasmosis | NA | BeFree | Detail | |
0.003 | Ocular Toxoplasmosis | NA | BeFree,GAD | Detail | |
0.006 | trachoma | NA | BeFree,GAD | Detail | |
0.002 | Chromosomal translocation | NA | GAD | Detail | |
<0.001 | Tremor | When early stage and late stage CSF cytokines were compared, IL-10 and IL-6 were... | BeFree | 26090964 | Detail |
0.003 | African Trypanosomiasis | Interleukin (IL)-6 and IL-10 Are Up Regulated in Late Stage Trypanosoma brucei r... | BeFree,GAD | 26090964 | Detail |
0.004 | Chagas disease | NA | BeFree,GAD | Detail | |
<0.001 | pleural tuberculosis | NA | BeFree | Detail | |
0.032 | Tuberculosis, Pulmonary | Independent and joint effects of the IL-6 and IL-10 gene polymorphisms in pulmon... | BeFree,GAD,LHGDN | 25299090 | Detail |
0.032 | Tuberculosis, Pulmonary | Moreover, the polymorphisms at IFN-γ -874 and IL10 - 1082 were associated with p... | BeFree,GAD,LHGDN | 25887222 | Detail |
<0.001 | Unipolar Depression | NA | BeFree | Detail | |
<0.001 | Upper Respiratory Infections | IL-10 G-1082A gene polymorphism and susceptibility to upper respiratory tract in... | BeFree | 24844623 | Detail |
0.002 | uremia | NA | GAD | Detail | |
0.001 | urinary tract infection | NA | BeFree | Detail | |
0.002 | Uterine Diseases | NA | GAD | Detail | |
0.007 | uveitis | NA | BeFree,GAD | Detail | |
0.002 | anterior uveitis | NA | GAD | Detail | |
0.002 | Vascular Diseases | NA | GAD | Detail | |
0.003 | vasculitis | NA | BeFree,GAD | Detail | |
0.005 | Venous Thrombosis | NA | GAD,LHGDN | Detail | |
0.002 | Viremia | NA | GAD | Detail | |
0.005 | Virus Diseases | Whereas IL-10 is important in terminating pro-inflammatory and antiviral immune ... | BeFree | 25430775 | Detail |
0.005 | Virus Diseases | This study investigated genetic variability in the IL-10 gene promoter between p... | BeFree | 25797191 | Detail |
0.006 | vitiligo | The combination of tumour necrosis factor-α -308A and interleukin-10 -1082G gene... | BeFree,GAD | 25283497 | Detail |
<0.001 | intestinal volvulus | Isolated PBMCs from O. volvulus-infected individuals (164 MF(+) and 46 a-MF) and... | BeFree | 25889652 | Detail |
0.001 | Wheezing | NA | BeFree | Detail | |
<0.001 | Yersinia infections | NA | BeFree | Detail | |
0.052 | Helicobacter Infections | NA | GAD | Detail | |
0.004 | holoprosencephaly | NA | BeFree | Detail | |
0.016 | B-Cell Lymphomas | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | High Grade Lymphoma (neoplasm) | NA | BeFree | Detail | |
<0.001 | Lymphoma, Intermediate-Grade | NA | BeFree | Detail | |
0.016 | diffuse large B-cell lymphoma | We hypothesized that DLBCLs depend for their proliferation and survival on IL10-... | BeFree,GAD | 25733167 | Detail |
0.002 | Lymphoma, Large-Cell, Follicular | NA | BeFree | Detail | |
0.004 | T-Cell Lymphoma | NA | BeFree,GAD | Detail | |
0.002 | Lymphoma, T-Cell, Cutaneous | These findings provide the first insights into the BZ-regulated TGF-β1 and IL-10... | BeFree | 25681335 | Detail |
0.002 | Disorder of the genitourinary system | NA | GAD | Detail | |
<0.001 | Fungemia | NA | BeFree | Detail | |
0.003 | Lymphoma, AIDS-Related | NA | BeFree,GAD | Detail | |
0.002 | Peripheral Vascular Diseases | NA | GAD | Detail | |
<0.001 | severe combined immunodeficiency | NA | BeFree | Detail | |
0.005 | Bronchial Hyperreactivity | NA | BeFree,GAD,LHGDN | Detail | |
0.002 | Central Nervous System Neoplasms | NA | GAD | Detail | |
0.003 | bacterial vaginosis | NA | BeFree,GAD | Detail | |
0.003 | gestational diabetes | NA | BeFree,GAD | Detail | |
<0.001 | hepatitis E | NA | BeFree | Detail | |
<0.001 | Diffuse cutaneous leishmaniasis | NA | BeFree | Detail | |
0.003 | Arthritis, Reactive | NA | BeFree,GAD | Detail | |
<0.001 | Encephalopathies | NA | BeFree | Detail | |
0.002 | Liver failure | NA | GAD | Detail | |
<0.001 | Chronic gastritis | NA | BeFree | Detail | |
<0.001 | Monocytosis | NA | BeFree | Detail | |
<0.001 | Hypogammaglobulinemia | NA | BeFree | Detail | |
<0.001 | Idiopathic Membranous Glomerulonephritis | NA | BeFree | Detail | |
<0.001 | Sicca Syndrome | NA | BeFree | Detail | |
0.006 | Pancreatitis, Chronic | NA | BeFree,GAD | Detail | |
0.017 | Epstein-Barr Virus Infections | NA | BeFree,GAD | Detail | |
0.003 | Left Ventricular Hypertrophy | NA | BeFree,GAD | Detail | |
0.003 | Oral Ulcer | NA | BeFree,GAD | Detail | |
0.080 | sciatic neuropathy | NA | RGD | Detail | |
<0.001 | Active tuberculosis | NA | BeFree | Detail | |
0.024 | Premature Birth | NA | GAD | Detail | |
<0.001 | Myocardial Ischemia | NA | BeFree | Detail | |
0.001 | Cutaneous Melanoma | NA | BeFree | Detail | |
<0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
<0.001 | esophageal carcinoma | By contrast, the percentage of peripheral IL‑10‑producing Bregs (B10s) significa... | BeFree | 24969402 | Detail |
0.002 | retinal vasculitis | NA | GAD | Detail | |
<0.001 | Joint swelling | NA | BeFree | Detail | |
<0.001 | Idiopathic pulmonary hypertension | NA | BeFree | Detail | |
<0.001 | Toxoplasmosis chorioretinitis | NA | BeFree | Detail | |
0.001 | Malignant neoplasm of mouth | TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer... | BeFree | 25744234 | Detail |
<0.001 | Malignant neoplasm of oropharynx | NA | BeFree | Detail | |
<0.001 | Secondary malignant neoplasm of lung | NA | BeFree | Detail | |
<0.001 | Hearing Loss, Mixed Conductive-Sensorineural | NA | BeFree | Detail | |
0.001 | acute myocardial infarction | NA | BeFree | Detail | |
0.003 | allergic asthma | The possible role of IL-10 as a therapy in allergic asthma has already been sugg... | BeFree | 25430775 | Detail |
<0.001 | intrinsic asthma | NA | BeFree | Detail | |
0.002 | adrenoleukodystrophy | NA | BeFree | Detail | |
0.003 | Malnutrition | NA | BeFree,GAD | Detail | |
0.002 | AIDS-Related Opportunistic Infections | NA | GAD | Detail | |
0.006 | Immunoglobulin A deficiency (disorder) | NA | BeFree,GAD | Detail | |
0.005 | Liver Failure, Acute | NA | BeFree,GAD | Detail | |
<0.001 | acute intermittent porphyria | NA | BeFree | Detail | |
<0.001 | Cicatrix, Hypertrophic | Hypertrophic scar fibroblasts (HSFs) were treated with rhIL10-RGD, and the fibro... | BeFree | 25342264 | Detail |
0.121 | Dermatitis, Allergic Contact | NA | BeFree,CTD_human | Detail | |
0.002 | Dermatitis, Irritant | NA | GAD | Detail | |
0.002 | Aneurysm, Ruptured | NA | GAD | Detail | |
0.015 | Aortic Aneurysm, Abdominal | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Autoimmune thyroid disease | NA | BeFree | Detail | |
0.003 | Tumor Progression | NA | BeFree | Detail | |
<0.001 | Undifferentiated carcinoma | NA | BeFree | Detail | |
0.001 | Diabetes, Autoimmune | NA | BeFree | Detail | |
0.005 | Lung Diseases, Interstitial | NA | BeFree,GAD | Detail | |
0.002 | Periodontal Attachment Loss | NA | GAD | Detail | |
0.008 | Lichen Planus, Oral | TNF-α, TNF-β and IL-10 gene polymorphism and association with oral lichen planus... | BeFree,GAD | 26221924 | Detail |
0.003 | Cytomegalovirus retinitis | NA | BeFree,GAD | Detail | |
<0.001 | Ki-1+ Anaplastic Large Cell Lymphoma | NA | BeFree | Detail | |
<0.001 | Lymphomatoid Papulosis | NA | BeFree | Detail | |
<0.001 | adenosquamous carcinoma | NA | BeFree | Detail | |
0.002 | Adenomatous Polyps | NA | GAD | Detail | |
<0.001 | cholangiocarcinoma | NA | BeFree | Detail | |
<0.001 | Carcinoma, Large Cell | NA | BeFree | Detail | |
0.008 | Cervical Intraepithelial Neoplasia | Interleukin-10 gene -1082 G/A polymorphism in cervical cancer and cervical intra... | BeFree,GAD | 25281063 | Detail |
0.003 | Squamous Cell Neoplasms | NA | LHGDN | Detail | |
0.002 | Alphavirus Infections | NA | GAD | Detail | |
0.001 | Lip and oral cavity carcinoma | TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer... | BeFree | 25744234 | Detail |
<0.001 | X-linked agammaglobulinemia | NA | BeFree | Detail | |
<0.001 | Adult type dermatomyositis | NA | BeFree | Detail | |
0.080 | Depression, Postpartum | NA | RGD | Detail | |
0.002 | Lytic lesion | NA | GAD | Detail | |
<0.001 | Trichiasis | NA | BeFree | Detail | |
0.002 | Pseudolymphoma | NA | GAD | Detail | |
<0.001 | Lesion of brain | NA | BeFree | Detail | |
0.003 | alpha 1-antitrypsin deficiency | NA | BeFree,GAD | Detail | |
<0.001 | Memory impairment | IL-10 expression resulted in increased Aβ accumulation and impaired memory in AP... | BeFree | 25619653 | Detail |
<0.001 | Muscle degeneration | NA | BeFree | Detail | |
0.080 | Neurotoxicity Syndromes | NA | RGD | Detail | |
<0.001 | Vitritis | NA | BeFree | Detail | |
<0.001 | pancreatic carcinoma | Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IF... | BeFree | 25725585 | Detail |
0.002 | Small for gestational age (disorder) | NA | GAD | Detail | |
0.002 | Substance-Related Disorders | NA | GAD | Detail | |
0.002 | Cancer of Nasopharynx | NA | GAD | Detail | |
<0.001 | Anaplastic thyroid carcinoma | NA | BeFree | Detail | |
<0.001 | Papillary thyroid carcinoma | NA | BeFree | Detail | |
<0.001 | Anemia, severe | NA | BeFree | Detail | |
0.003 | Fibrosis, Liver | Influence of IL10 gene polymorphisms on the severity of liver fibrosis and susce... | BeFree | 25514046 | Detail |
<0.001 | Interstitial fibrosis | NA | BeFree | Detail | |
0.125 | Hepatitis, Autoimmune | NA | BeFree,CTD_human,GAD | Detail | |
0.002 | coronary stenosis | NA | GAD | Detail | |
<0.001 | Dyslipidemias | Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL defic... | BeFree | 25670364 | Detail |
0.025 | Malignant neoplasm of lung | Interleukin-10 (IL-10) promoter genotypes are associated with lung cancer risk i... | BeFree,GAD | 25503130 | Detail |
<0.001 | Lyme Arthritis | NA | BeFree | Detail | |
0.005 | age related macular degeneration | NA | GAD | Detail | |
0.082 | Acute Lung Injury | NA | GAD,RGD | Detail | |
<0.001 | intestinal schistosomiasis | NA | BeFree | Detail | |
<0.001 | Drug usage | No association was found between C. difficile carriage and chemotherapy regimen,... | BeFree | 25267108 | Detail |
0.002 | Mucosa-Associated Lymphoid Tissue Lymphoma | NA | GAD | Detail | |
0.003 | Disease Progression | NA | LHGDN | Detail | |
0.005 | Parasitemia | NA | BeFree,GAD | Detail | |
<0.001 | Systemic Inflammatory Response Syndrome | NA | BeFree | Detail | |
<0.001 | Hantavirus Infections | NA | BeFree | Detail | |
0.260 | Sepsis | Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis ... | BeFree,CTD_human,GAD,LHGDN,RGD | 25348624 | Detail |
0.260 | Sepsis | Association between interleukin-10 polymorphisms and sepsis: a meta-analysis. | BeFree,CTD_human,GAD,LHGDN,RGD | 25497741 | Detail |
<0.001 | Carcinoma, Lewis Lung | NA | BeFree | Detail | |
<0.001 | Psoriasiform eczema | NA | BeFree | Detail | |
<0.001 | Vasculitis of the skin | NA | BeFree | Detail | |
<0.001 | Psoriasis vulgaris | Several studies have reported an association between interleukin 10 (IL-10) vari... | BeFree | 25735363 | Detail |
<0.001 | Chronic arthritis | NA | BeFree | Detail | |
<0.001 | Osteoarthritis of the hand | Variations in the TNFα gene and their interactions with the IL4R and IL10 genes ... | BeFree | 25252624 | Detail |
<0.001 | Interphalangeal osteoarthritis | NA | BeFree | Detail | |
0.002 | Childhood asthma | NA | BeFree | Detail | |
<0.001 | Acute respiratory failure | NA | BeFree | Detail | |
<0.001 | Congenital anomaly of brain | NA | BeFree | Detail | |
<0.001 | Rachischisis | NA | BeFree | Detail | |
0.020 | Chronic Periodontitis | Association of -1082 interleukin-10 gene polymorphism in Peruvian adults with ch... | BeFree,GAD,LHGDN | 25129246 | Detail |
0.003 | Chronic colitis | In this study, we investigated the role of inflammasome activation in the develo... | BeFree | 24472848 | Detail |
0.003 | Chronic colitis | Chronic colitis was induced in interleukin 10-deficient mice. | BeFree | 25072499 | Detail |
0.001 | Typhlocolitis | NA | BeFree | Detail | |
<0.001 | Pancreatitis, Acute Necrotizing | NA | BeFree | Detail | |
0.050 | hepatitis B | A recent genome-wide association study discovered that two polymorphisms, interf... | BeFree | 19714778 | Detail |
<0.001 | macular retinal edema | In addition, the aqueous humor levels of IL-10 and IL-12 decreased with increasi... | BeFree | 25923230 | Detail |
<0.001 | Eales disease | NA | BeFree | Detail | |
<0.001 | Severe myopia | NA | BeFree | Detail | |
<0.001 | Coinfection | NA | BeFree | Detail | |
<0.001 | Lyme carditis | NA | BeFree | Detail | |
<0.001 | Bacterial osteomyelitis | NA | BeFree | Detail | |
0.002 | Disease due to Parvoviridae | NA | GAD | Detail | |
<0.001 | Respiratory syncytial virus bronchiolitis | NA | BeFree | Detail | |
<0.001 | Acute viral hepatitis | NA | BeFree | Detail | |
0.003 | Invasive Pulmonary Aspergillosis | NA | BeFree,LHGDN | Detail | |
<0.001 | Carcinoma breast stage IV | NA | BeFree | Detail | |
<0.001 | recurrent childhood acute lymphoblastic leukemia | NA | BeFree | Detail | |
<0.001 | Ovarian epithelial cancer recurrent | NA | BeFree | Detail | |
<0.001 | Disseminated neuroblastoma | In conclusion, although IL-10 concentration and Treg percentage were increased, ... | BeFree | 25961062 | Detail |
<0.001 | Disseminated neuroblastoma | Since the immune status of the tumor microenvironment could play a role in the h... | BeFree | 26161395 | Detail |
<0.001 | gastric adenocarcinoma | NA | BeFree | Detail | |
<0.001 | Metastatic melanoma | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of esophagus | There was a significant correlation between sHLA-G and IL-10 expression (r=0.353... | BeFree | 24768599 | Detail |
0.001 | Solid tumour | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of oropharynx | NA | BeFree | Detail | |
0.001 | intraocular lymphoma | NA | BeFree | Detail | |
0.001 | Very Low Birth Weight | NA | BeFree | Detail | |
<0.001 | Hemorrhagic Fever, Ebola | NA | BeFree | Detail | |
<0.001 | Disease caused by Shigella dysenteriae | NA | BeFree | Detail | |
0.009 | cervix carcinoma | Interleukin-10 gene -1082 G/A polymorphism in cervical cancer and cervical intra... | BeFree,GAD | 25281063 | Detail |
0.009 | cervix carcinoma | Association of IL-10 GTC haplotype with serum level and HPV infection in the dev... | BeFree,GAD | 25412954 | Detail |
<0.001 | Fulminant hepatitis | NA | BeFree | Detail | |
<0.001 | Uremia syndrome | NA | BeFree | Detail | |
<0.001 | Restenosis | NA | BeFree | Detail | |
0.120 | Inflammatory disease of mucous membrane | NA | CTD_human | Detail | |
<0.001 | Senile Plaques | NA | BeFree | Detail | |
<0.001 | Segmental glomerulosclerosis | NA | BeFree | Detail | |
<0.001 | Tumor necrosis | NA | BeFree | Detail | |
<0.001 | Caries (morphologic abnormality) | NA | BeFree | Detail | |
<0.001 | Squamous intraepithelial lesion | NA | BeFree | Detail | |
<0.001 | Lymphoid hyperplasia | NA | BeFree | Detail | |
<0.001 | Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | NA | BeFree | Detail | |
<0.001 | Adenocarcinoma of colon | NA | BeFree | Detail | |
<0.001 | Impaired cognition | NA | BeFree | Detail | |
0.003 | Thyroid associated opthalmopathies | NA | BeFree,GAD | Detail | |
<0.001 | Acute respiratory infections | NA | BeFree | Detail | |
<0.001 | Aspirin-sensitive asthma with nasal polyps | Aspirin desensitization was reported to decrease the levels of CD4⁺ T cell-deriv... | BeFree | 25546326 | Detail |
<0.001 | Stable angina | NA | BeFree | Detail | |
0.001 | Chronic liver disease | NA | BeFree | Detail | |
<0.001 | endometriosis of uterus | NA | BeFree | Detail | |
0.002 | Complications of Diabetes Mellitus | NA | GAD | Detail | |
<0.001 | Organ dysfunction syndrome | NA | BeFree | Detail | |
<0.001 | Microscopic Polyangiitis | NA | BeFree | Detail | |
<0.001 | Erythema nodosum leprosum | NA | BeFree | Detail | |
<0.001 | African Burkitt's lymphoma | NA | BeFree | Detail | |
<0.001 | Human papilloma virus infection | NA | BeFree | Detail | |
<0.001 | Chronic Chagas' disease | NA | BeFree | Detail | |
0.002 | Malignant neoplasm of liver | NA | GAD | Detail | |
<0.001 | Stage 0 Skin Melanoma | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of pancreas | Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IF... | BeFree | 25725585 | Detail |
<0.001 | Irritable bowel syndrome with diarrhea | The present study indicated the DQB1*02 or DQB1*0603 alleles are related to IBS-... | BeFree | 25501240 | Detail |
<0.001 | Nonorganic psychosis | NA | BeFree | Detail | |
<0.001 | Cervical intraepithelial neoplasia grade 2 | NA | BeFree | Detail | |
<0.001 | Common acute lymphoblastic leukemia | NA | BeFree | Detail | |
0.004 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | Hp GE-driven enhancement of lymphocyte cytotoxic activity was associated with th... | BeFree | 24448078 | Detail |
0.003 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | SNPs in several genes were associated with increased chronic respiratory morbidi... | BeFree | 24487983 | Detail |
0.003 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | Conversely, murine studies indicate that the combined actions of regulatory fact... | BeFree | 24838148 | Detail |
<0.001 | Malignant neoplasm of vulva | NA | BeFree | Detail | |
0.035 | Malignant neoplasm of prostate | We conclude that promoter genetic variants of IL-18 and IL-10 with various modes... | BeFree,GAD | 25921117 | Detail |
0.035 | Malignant neoplasm of prostate | The present study investigates the role of variations in the promoter regions of... | BeFree,GAD | 26277868 | Detail |
0.035 | Malignant neoplasm of prostate | Association of IL-1β and IL-10 Polymorphisms with Prostate Cancer Risk and Grade... | BeFree,GAD | 26753456 | Detail |
0.005 | Hematologic Neoplasms | NA | BeFree,GAD | Detail | |
0.082 | Endotoxemia | NA | GAD,RGD | Detail | |
<0.001 | Pouchitis | NA | BeFree | Detail | |
<0.001 | Pancreatitis, Alcoholic | The p values for IL 10 -819 C>T and IL 10 -1082 G>A were respectively 0.031 and ... | BeFree | 24835349 | Detail |
0.002 | Postoperative infection | NA | GAD | Detail | |
0.007 | Atopy | NA | GAD | Detail | |
0.003 | multiple system atrophy | NA | BeFree,GAD | Detail | |
<0.001 | Hashimoto's encephalitis | NA | BeFree | Detail | |
0.003 | Multiple Sclerosis, Chronic Progressive | NA | LHGDN | Detail | |
<0.001 | Recurrent acute otitis media | NA | BeFree | Detail | |
0.004 | Immune thrombocytopenic purpura | In the study we investigated the levels of IL-35 as well as its prospective role... | BeFree,GAD | 24994465 | Detail |
<0.001 | Early onset periodontitis | NA | BeFree | Detail | |
<0.001 | Non-alcoholic Fatty Liver Disease | NA | BeFree | Detail | |
0.080 | Anti-Glomerular Basement Membrane Disease | NA | RGD | Detail | |
<0.001 | Chronic pelvic pain of female | NA | BeFree | Detail | |
<0.001 | Osteoarthritis of distal interphalangeal joint | Variations in the TNFα gene and their interactions with the IL4R and IL10 genes ... | BeFree | 25252624 | Detail |
0.005 | Osteoarthritis, Knee | NA | BeFree,GAD | Detail | |
0.017 | lupus erythematosus | Stat3 promotes IL-10 expression in lupus T cells through trans-activation and ch... | BeFree,GAD | 25187566 | Detail |
<0.001 | Muscle damage | NA | BeFree | Detail | |
<0.001 | Chronic multifocal osteomyelitis | NA | BeFree | Detail | |
0.005 | Fever symptoms (finding) | NA | GAD | Detail | |
<0.001 | Arthritis by pattern of joint involvement | NA | BeFree | Detail | |
0.002 | Ichthyosis bullosa of Siemens | NA | BeFree | Detail | |
<0.001 | neuropathy | NA | BeFree | Detail | |
<0.001 | Nephrotic range proteinuria | NA | BeFree | Detail | |
<0.001 | Human anaplasmosis due to Anaplasma phagocytophilum | NA | BeFree | Detail | |
<0.001 | Alzheimer Disease, Late Onset | NA | BeFree | Detail | |
<0.001 | Benign neoplasm of brain, unspecified | NA | BeFree | Detail | |
<0.001 | hiv-infection/aids | NA | BeFree | Detail | |
<0.001 | dementia | NA | BeFree | Detail | |
<0.001 | Chlamydia trachomatis infection | NA | BeFree | Detail | |
0.080 | Necrotizing Enterocolitis | NA | BeFree,RGD | Detail | |
<0.001 | Chronic active hepatitis | NA | BeFree | Detail | |
0.001 | Granulomatosis | NA | BeFree | Detail | |
0.006 | Metabolic syndrome X | The low concentrations of IL-10 may suggest an anti-inflammatory modulation in p... | BeFree,GAD,LHGDN | 25329057 | Detail |
<0.001 | Neurodegenerative Disorders | Our observations that IL-10 has an unexpected negative effect on Aβ proteostasis... | BeFree | 25619653 | Detail |
0.025 | Hepatitis B, Chronic | Role of proinflammatory cytokines (interferon gamma) and anti-inflammatory cytok... | BeFree,GAD | 24446686 | Detail |
0.025 | Hepatitis B, Chronic | Myeloid-derived suppressor cells regulate immune response in patients with chron... | BeFree,GAD | 25344470 | Detail |
0.025 | Hepatitis B, Chronic | Association of the IFNAR1-17470 and IL-10-592 cytokine variants with susceptibil... | BeFree,GAD | 25501140 | Detail |
0.025 | Hepatitis B, Chronic | Previous studies about the association of the interleukin-10 (IL-10) polymorphis... | BeFree,GAD | 25514046 | Detail |
0.047 | Hepatitis C, Chronic | Haplotype analysis of interleukin-10 gene promoter polymorphisms in chronic hepa... | BeFree,GAD,LHGDN | 25119896 | Detail |
0.005 | Mood Disorders | NA | BeFree,GAD | Detail | |
<0.001 | Mixed cryoglobulinemia | NA | BeFree | Detail | |
0.010 | Malignant neoplasm of esophagus | By contrast, the percentage of peripheral IL‑10‑producing Bregs (B10s) significa... | BeFree,GAD | 24969402 | Detail |
<0.001 | X-Linked Lymphoproliferative Disorder | NA | BeFree | Detail | |
<0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
<0.001 | Oropharyngeal disorders | NA | BeFree | Detail | |
0.003 | Squamous cell carcinoma of skin | NA | BeFree,GAD | Detail | |
<0.001 | Malignant glioma | NA | BeFree | Detail | |
<0.001 | primary sclerosing cholangitis | NA | BeFree | Detail | |
<0.001 | acute asthma | NA | BeFree | Detail | |
0.001 | Minor oral aphthous ulceration | NA | BeFree | Detail | |
0.001 | Aqueous Humor Disorders | In addition, the aqueous humor levels of IL-10 and IL-12 decreased with increasi... | BeFree | 25923230 | Detail |
0.007 | Carcinogenesis | Interleukin-10 (IL10) is a pleiotropic cytokine produced by macrophages which ca... | BeFree | 25189915 | Detail |
0.007 | Carcinogenesis | Interleukin-10 (IL-10) is an immunosuppressive cytokine involved in carcinogenes... | BeFree | 25503130 | Detail |
<0.001 | Chemical Carcinogenesis | NA | BeFree | Detail | |
0.001 | Leukemogenesis | NA | BeFree | Detail | |
<0.001 | monocytic leukemia | NA | BeFree | Detail | |
0.005 | prostate carcinoma | Pro-(IL-18) and Anti-(IL-10) Inflammatory Promoter Genetic Variants (Intrinsic F... | BeFree | 25921117 | Detail |
0.005 | prostate carcinoma | Functional genetic variability at promoters of pro-(IL-18) and anti-(IL-10) infl... | BeFree | 26277868 | Detail |
0.005 | prostate carcinoma | Association of IL-1β and IL-10 Polymorphisms with Prostate Cancer Risk and Grade... | BeFree | 26753456 | Detail |
<0.001 | toxic shock syndrome | NA | BeFree | Detail | |
0.002 | Choroidal Neovascularization | NA | GAD | Detail | |
<0.001 | CARCINOMA OF VULVA | NA | BeFree | Detail | |
<0.001 | Gastro-esophageal reflux disease with esophagitis | NA | BeFree | Detail | |
0.004 | Epithelial ovarian cancer | NA | BeFree,GAD | Detail | |
0.001 | Progressive Neoplastic Disease | NA | BeFree | Detail | |
<0.001 | Sentinel node (disorder) | NA | BeFree | Detail | |
0.007 | breast carcinoma | LPS triggered increased expression of TLR4 downstream signaling pathway protein ... | BeFree | 25299052 | Detail |
0.007 | breast carcinoma | NFKB1, NFKBIA, IL-8, IL-10, and TNF polymorphisms could serve as useful predicti... | BeFree | 25559835 | Detail |
<0.001 | Tuberculosis, extrapulmonary | NA | BeFree | Detail | |
0.003 | Carcinoma of lung | Interleukin-10 (IL-10) promoter genotypes are associated with lung cancer risk i... | BeFree | 25503130 | Detail |
<0.001 | Malignant neoplasm of gastrointestinal tract | The -1082A>G polymorphism in promoter region of interleukin-10 and risk of diges... | BeFree | 25091209 | Detail |
<0.001 | Secondary malignant neoplasm of lymph node | NA | BeFree | Detail | |
<0.001 | heavy drinking | NA | BeFree | Detail | |
0.005 | Pregnancy loss | NA | GAD | Detail | |
<0.001 | Community acquired pneumonia | NA | BeFree | Detail | |
<0.001 | Infection of ear | NA | BeFree | Detail | |
0.002 | colon carcinoma | NA | BeFree | Detail | |
0.017 | stomach carcinoma | The allele flip observed in IL-10 and gastric cancer appears to reflect allelic ... | BeFree,GAD | 24782608 | Detail |
0.017 | stomach carcinoma | Based on 40 studies and 18950 participants, we found the variant IL-10 -1082G al... | BeFree,GAD | 25091209 | Detail |
0.017 | stomach carcinoma | Effects of interleukin-10 polymorphisms and smoking on the risk of gastric cance... | BeFree,GAD | 25189915 | Detail |
0.017 | stomach carcinoma | Interleukin-10 gene -592C>A polymorphism and susceptibility to gastric cancer. | BeFree,GAD | 25366786 | Detail |
0.017 | stomach carcinoma | Clinical study on gastric cancer susceptibility genes IL-10-1082 and TNF-α. | BeFree,GAD | 25526211 | Detail |
0.001 | Carcinoma of bladder | NA | BeFree | Detail | |
0.003 | skin carcinoma | NA | BeFree,GAD | Detail | |
<0.001 | airway disease | NA | BeFree | Detail | |
<0.001 | Acute anterior uveitis | NA | BeFree | Detail | |
<0.001 | Dissecting aneurysm of the thoracic aorta | NA | BeFree | Detail | |
<0.001 | Viral respiratory infection | NA | BeFree | Detail | |
<0.001 | Punctate inner choroidopathy | NA | BeFree | Detail | |
0.005 | Malignant neoplasm of kidney | NA | BeFree,GAD | Detail | |
<0.001 | central nervous system lymphoma | NA | BeFree | Detail | |
<0.001 | gastric ulcer benign | NA | BeFree | Detail | |
0.003 | infertility tubal factor | NA | BeFree,GAD | Detail | |
0.002 | Scleroderma, Limited | NA | GAD | Detail | |
<0.001 | Hyperalgesia, Thermal | NA | BeFree | Detail | |
0.004 | Multiple Sclerosis, Relapsing-Remitting | Here, we investigated the roles of inflammasomes [absent in melanoma 2 (AIM2); N... | BeFree,LHGDN | 25586466 | Detail |
0.004 | Multiple Sclerosis, Relapsing-Remitting | Our recent studies suggest that MS peripheral blood B cells secrete higher quant... | BeFree,LHGDN | 25794663 | Detail |
<0.001 | Myasthenia Gravis, Autoimmune, Experimental | NA | BeFree | Detail | |
<0.001 | Neuropsychiatric Systemic Lupus Erythematosus | NA | BeFree | Detail | |
<0.001 | Subfertility, Male | NA | BeFree | Detail | |
<0.001 | neurological disability | NA | BeFree | Detail | |
0.009 | Helicobacter pylori infection | Together, these results demonstrate that H. pylori infection induces IL-10 secre... | BeFree,GAD | 25412627 | Detail |
<0.001 | Anaphylaxis (non medication) | NA | BeFree | Detail | |
<0.001 | Carcinoma in situ of uterine cervix | NA | BeFree | Detail | |
0.080 | Diabetic Cardiomyopathies | NA | RGD | Detail | |
<0.001 | Endothelial dysfunction | Interleukin-10 affects maternal intravascular inflammation, as well as endotheli... | BeFree | 24477695 | Detail |
0.002 | High altitude illness | NA | GAD | Detail | |
0.006 | Acute GVH disease | Association between interleukin-10 promoter gene polymorphisms and acute graft-v... | BeFree | 25116082 | Detail |
0.005 | Drug-Induced Liver Injury | NA | GAD | Detail | |
0.002 | Chronic graft-versus-host disease | NA | BeFree | Detail | |
<0.001 | Carditis | NA | BeFree | Detail | |
<0.001 | latent infection | NA | BeFree | Detail | |
<0.001 | Infectious disease of lung | NA | BeFree | Detail | |
<0.001 | Advanced cancer | NA | BeFree | Detail | |
<0.001 | Candidemia | NA | BeFree | Detail | |
0.006 | Cardiomyopathies | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Cerebral Ischemia | NA | BeFree | Detail | |
0.003 | ovarian neoplasm | NA | BeFree,LHGDN | Detail | |
<0.001 | Renal ischaemia | NA | BeFree | Detail | |
<0.001 | precancerous lesions | Role of cytokine gene (interferon-γ, transforming growth factor-β1, tumor necros... | BeFree | 25458044 | Detail |
<0.001 | Vascular inflammations | NA | BeFree | Detail | |
0.002 | Ischemic stroke | We aimed to investigate the association of inflammation-related genes such as IL... | BeFree | 24782217 | Detail |
0.004 | Acute coronary syndrome | NA | BeFree,GAD | Detail | |
0.007 | coronary restenosis | NA | GAD | Detail | |
<0.001 | Rhinosinusitis | NA | BeFree | Detail | |
<0.001 | alveolar echinococcosis | NA | BeFree | Detail | |
<0.001 | Polyp of large intestine | NA | BeFree | Detail | |
<0.001 | IIeocolitis | NA | BeFree | Detail | |
0.001 | Spondylarthritis | NA | BeFree | Detail | |
0.003 | Spondylarthropathies | NA | BeFree,GAD | Detail | |
0.012 | Papillomavirus Infections | NA | BeFree,GAD | Detail | |
0.003 | Arthritis, Collagen-Induced | APL-2, an altered peptide ligand derived from heat-shock protein 60, induces int... | BeFree | 24474501 | Detail |
0.003 | Arthritis, Collagen-Induced | Pre-clinical Vac-PSG1a treatment suppressed the Th1- and Th17-type-specific resp... | BeFree | 25112392 | Detail |
0.201 | Arthritis, Experimental | NA | BeFree,CTD_human,RGD | Detail | |
<0.001 | West Nile viral infection | NA | BeFree | Detail | |
<0.001 | Stage 4S neuroblastoma | In conclusion, although IL-10 concentration and Treg percentage were increased, ... | BeFree | 25961062 | Detail |
<0.001 | Stage 4S neuroblastoma | Since the immune status of the tumor microenvironment could play a role in the h... | BeFree | 26161395 | Detail |
0.002 | Heart Failure, Diastolic | NA | GAD | Detail | |
0.005 | Malignant neoplasm of ovary | NA | BeFree,GAD | Detail | |
<0.001 | Bacteremia due to Staphylococcus aureus | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
0.005 | severe acute respiratory syndrome | NA | BeFree,GAD | Detail | |
0.002 | diffuse scleroderma | NA | GAD | Detail | |
<0.001 | Abnormal breathing | NA | BeFree | Detail | |
<0.001 | sarcoma | NA | BeFree | Detail | |
0.120 | Weight decreased | NA | CTD_human | Detail | |
0.002 | Persistent infection | Significantly, AA homozygous genotype was dominant in chronic hepatitis B cases ... | BeFree | 24446686 | Detail |
0.002 | Persistent infection | However, the IL-10-592 and -819 genotypes were not found significant difference ... | BeFree | 25613737 | Detail |
<0.001 | Thyroid Gland Spindle Cell Tumor with Thymus-Like Differentiation | NA | BeFree | Detail | |
0.003 | major depressive disorder | NA | BeFree,GAD | Detail | |
<0.001 | T-lymphocyte immunodeficiency | NA | BeFree | Detail | |
<0.001 | Acral pseudolymphomatous angiokeratoma of children (APACHE) | NA | BeFree | Detail | |
<0.001 | TNF receptor-associated periodic fever syndrome (TRAPS) | NA | BeFree | Detail | |
<0.001 | Tumor stage mycosis fungoides | NA | BeFree | Detail | |
<0.001 | Cutaneous lymphoma | NA | BeFree | Detail | |
<0.001 | Chronic leukemia (category) | NA | BeFree | Detail | |
0.002 | Inflammatory disorder | Several studies have reported an association between interleukin 10 (IL-10) vari... | BeFree | 25735363 | Detail |
<0.001 | Primary Effusion Lymphoma | NA | BeFree | Detail | |
<0.001 | Precursor B-cell lymphoblastic leukemia | NA | BeFree | Detail | |
<0.001 | Cardiovascular morbidity | NA | BeFree | Detail | |
<0.001 | Respiratory morbidity | SNPs in several genes were associated with increased chronic respiratory morbidi... | BeFree | 24487983 | Detail |
<0.001 | Adenoma of large intestine | NA | BeFree | Detail | |
<0.001 | Necrotic melanoma | NA | BeFree | Detail | |
<0.001 | Low Grade Squamous Intraepithelial Neoplasia | At first recruitment of women with LSIL (100 cases), IL-10 mRNA and cytokine in ... | BeFree | 24935370 | Detail |
<0.001 | Early onset psoriasis type 1 | NA | BeFree | Detail | |
<0.001 | Familial psoriasis | NA | BeFree | Detail | |
0.001 | Eosinophilic disorder | We found that both clarithromycin and dexamethasone up-regulated the production ... | BeFree | 26047816 | Detail |
<0.001 | M5b Acute differentiated monocytic leukemia | NA | BeFree | Detail | |
<0.001 | Autologous graft versus host disease | NA | BeFree | Detail | |
0.002 | autoimmune lymphoproliferative syndrome | IL-10/Janus kinase/signal transducer and activator of transcription 3 signaling ... | BeFree | 25174872 | Detail |
<0.001 | AIDS-Related Non-Hodgkin Lymphoma | NA | BeFree | Detail | |
<0.001 | Aggressive Non-Hodgkin Lymphoma | NA | BeFree | Detail | |
<0.001 | Classical Hodgkin's Lymphoma | NA | BeFree | Detail | |
<0.001 | Infiltrating Cervical Carcinoma | NA | BeFree | Detail | |
<0.001 | Invasive Carcinoma | NA | BeFree | Detail | |
<0.001 | Ovarian Serous Adenocarcinoma | NA | BeFree | Detail | |
<0.001 | renal carcinoma | NA | BeFree | Detail | |
<0.001 | Systemic onset juvenile chronic arthritis | NA | BeFree | Detail | |
0.080 | hearing impairment | NA | RGD | Detail | |
<0.001 | Vascular lesions | NA | BeFree | Detail | |
<0.001 | Chronic Q Fever | For TLR1, increased interleukin 10 responses to C. burnetii in individuals carry... | BeFree | 25722298 | Detail |
<0.001 | Cardiomyopathy, Familial Idiopathic | NA | BeFree | Detail | |
<0.001 | Bacteroides fragilis infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
<0.001 | Polio and Post-Polio Syndrome | NA | BeFree | Detail | |
0.011 | Mammary Neoplasms | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Idiopathic pneumonia syndrome | NA | BeFree | Detail | |
0.002 | Human T-cell lymphotropic virus 1 infection | NA | GAD | Detail | |
<0.001 | Cancer Cell Growth | NA | BeFree | Detail | |
<0.001 | Tumor-Associated Vasculature | These results indicate that rhIL10-RGD has anti-fibrosis effects and can potenti... | BeFree | 25342264 | Detail |
<0.001 | Tumor Angiogenesis | NA | BeFree | Detail | |
<0.001 | Tumor Immunity | Our results suggest that mutations that disrupt the interactions of IL-10 with i... | BeFree | 25056661 | Detail |
<0.001 | Xenograft Model | NA | BeFree | Detail | |
0.023 | Sjogren's syndrome | Increasing evidence indicates that IL-10 plays an important role in both the ons... | BeFree,GAD,LHGDN | 24639111 | Detail |
0.002 | Brain Hypoxia | NA | GAD | Detail | |
<0.001 | Multifocal choroiditis | NA | BeFree | Detail | |
<0.001 | fertility disorders | NA | BeFree | Detail | |
<0.001 | infective endocarditis | In this study, 14 single nucleotide variants (SNVs) in genes coding for interleu... | BeFree | 25299518 | Detail |
0.001 | Non-Malignant Ascites Adverse Event | NA | BeFree | Detail | |
<0.001 | Leprosy, Multibacillary | NA | BeFree | Detail | |
<0.001 | Leprosy, Paucibacillary | NA | BeFree | Detail | |
<0.001 | Cold Ischemia | NA | BeFree | Detail | |
0.003 | Renal Insufficiency | NA | BeFree,GAD | Detail | |
0.002 | Delayed Graft Function | NA | GAD | Detail | |
<0.001 | Immune Reconstitution Inflammatory Syndrome | NA | BeFree | Detail | |
<0.001 | Glioblastoma multiforme | NA | BeFree | Detail | |
0.001 | Cirrhosis | Moreover, the IL-10 protein and mRNA levels in peripheral blood mono nuclear cel... | BeFree | 25027084 | Detail |
0.001 | Cirrhosis | Previous studies about the association of the interleukin-10 (IL-10) polymorphis... | BeFree | 25514046 | Detail |
0.001 | Disorder characterized by eosinophilia | We found that both clarithromycin and dexamethasone up-regulated the production ... | BeFree | 26047816 | Detail |
<0.001 | Benign Prostatic Hyperplasia | NA | BeFree | Detail | |
<0.001 | Peripheral Arterial Diseases | NA | BeFree | Detail | |
<0.001 | Neonatal Deformity | NA | BeFree | Detail | |
<0.001 | Atopic IgE-mediated allergic disorder | NA | BeFree | Detail | |
<0.001 | Non-Neoplastic Disorder | NA | BeFree | Detail | |
0.001 | Aggressive periodontitis, generalized | NA | BeFree | Detail | |
<0.001 | Generalized chronic periodontitis | NA | BeFree | Detail | |
0.001 | Severe Sepsis | NA | BeFree | Detail | |
<0.001 | Idiopathic Pulmonary Fibrosis | NA | BeFree | Detail | |
<0.001 | Chromosome 11p11.2 Deletion Syndrome | NA | BeFree | Detail | |
0.120 | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO | NA | CLINVAR | Detail | |
<0.001 | FRAGILE X TREMOR/ATAXIA SYNDROME | NA | BeFree | Detail | |
0.003 | IMMUNE SUPPRESSION | Herein, we describe a protocol for in vitro synthesis of small interfering RNA a... | BeFree | 25319657 | Detail |
0.003 | IMMUNE SUPPRESSION | The stimulation of peripheral blood mononuclear cells with r-LdODC up-regulated ... | BeFree | 25449949 | Detail |
0.003 | IMMUNE SUPPRESSION | The combination of oral delivery of bioencapsulated FIX and intravenous replacem... | BeFree | 25700434 | Detail |
<0.001 | Aural atresia, congenital | Our data support the possibility that IL-10 gene polymorphisms may be related wi... | BeFree | 24659220 | Detail |
0.002 | VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | The combination of tumour necrosis factor-α -308A and interleukin-10 -1082G gene... | BeFree | 25283497 | Detail |
<0.001 | peeling skin syndrome | NA | BeFree | Detail | |
<0.001 | Neuropathy, Painful | NA | BeFree | Detail | |
<0.001 | Myeloproliferative disorder, chronic, with eosinophilia | It was also noted that high levels of IL-10, TGF-β1 and CCL17 were observed in M... | BeFree | 25371165 | Detail |
<0.001 | Endotoxin Hyporesponsiveness | NA | BeFree | Detail | |
0.017 | coronary artery disease | NA | BeFree,GAD,LHGDN | Detail | |
0.002 | temporal arteritis | NA | GAD | Detail | |
0.013 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree,GAD,LHGDN | Detail | |
0.105 | liver carcinoma | The present study was designed to evaluate the impact of IL-10 (-819/-592) genot... | BeFree,GAD,LHGDN,RGD | 25027084 | Detail |
<0.001 | Chronic idiopathic neutropenia | NA | BeFree | Detail | |
<0.001 | Chronic kidney disease stage 5 | NA | BeFree | Detail | |
<0.001 | Oropharyngeal Carcinoma | NA | BeFree | Detail | |
0.080 | Ventilator-Induced Lung Injury | NA | RGD | Detail | |
0.005 | Allergic rhinitis (disorder) | In vitro HDM challenge presents concordant patterns with in vivo findings: 1) in... | BeFree,GAD | 24647473 | Detail |
<0.001 | autoimmune pancreatitis | NA | BeFree | Detail | |
0.120 | Acute kidney injury | NA | CTD_human | Detail | |
0.080 | inflammatory bowel disease 23 | NA | MGD | Detail | |
<0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
0.002 | Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified | NA | GAD | Detail | |
0.017 | Chronic ulcerative colitis | NA | GAD | Detail | |
0.002 | Recurrent pregnancy loss | NA | GAD | Detail | |
<0.001 | Chronic malaria | NA | BeFree | Detail | |
<0.001 | Immunoglobulin a deficiency 1 | NA | BeFree | Detail | |
<0.001 | Moyamoya disease 1 | NA | BeFree | Detail | |
0.002 | Nasopharyngeal carcinoma | NA | BeFree | Detail | |
<0.001 | Mechanical Allodynia | NA | BeFree | Detail | |
0.001 | Recurrent aphthous ulcer | NA | BeFree | Detail | |
0.002 | Prostatic Hyperplasia | NA | GAD | Detail | |
<0.001 | Disturbance in mood | NA | BeFree | Detail | |
0.003 | Deficiency of glucose-6-phosphate dehydrogenase | NA | BeFree,GAD | Detail | |
<0.001 | Pulmonary arterial hypertension | NA | BeFree | Detail | |
<0.001 | Immunoglobulin G4 related sclerosing disease | Real-time polymerase chain reaction analysis confirmed the significant upregulat... | BeFree | 24390219 | Detail |
0.002 | Ischemic Cerebrovascular Accident | We aimed to investigate the association of inflammation-related genes such as IL... | BeFree | 24782217 | Detail |
<0.001 | Small fiber neuropathy | NA | BeFree | Detail | |
0.002 | myelodysplastic syndrome | NA | GAD | Detail | |
0.002 | Hiatal Hernia | NA | GAD | Detail | |
0.021 | Juvenile arthritis | NA | BeFree,GAD,LHGDN | Detail | |
0.012 | granulomatosis with polyangiitis | NA | GAD,LHGDN | Detail | |
0.001 | Progressive cGVHD | NA | BeFree | Detail | |
0.005 | Allergic disposition | NA | BeFree | Detail | |
<0.001 | Drug Hypersensitivity Syndrome | NA | BeFree | Detail | |
<0.001 | aortic valve disease 2 | NA | BeFree | Detail | |
<0.001 | Allergic sensitization | NA | BeFree | Detail | |
<0.001 | Neutrophilia (disorder) | We found that both clarithromycin and dexamethasone up-regulated the production ... | BeFree | 26047816 | Detail |
<0.001 | Nonsyndromic Holoprosencephaly | NA | BeFree | Detail | |
0.072 | Infection | NA | GAD,LHGDN | Detail | |
<0.001 | Staphylococcal toxic shock syndrome | NA | BeFree | Detail | |
<0.001 | Pneumonitis | Associations of three well-characterized polymorphisms in the IL-6 and IL-10 gen... | BeFree | 25708204 | Detail |
<0.001 | Pneumonitis | Interestingly, we observed that all BI patients with high frequency of IL-10(+) ... | BeFree | 26364142 | Detail |
0.002 | Thymus Neoplasms | NA | GAD | Detail | |
0.002 | juvenile rheumatoid arthritis | NA | BeFree | Detail | |
<0.001 | Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia | NA | BeFree | Detail | |
0.001 | Experimental Organism Basal Cell Carcinoma | NA | BeFree | Detail | |
<0.001 | Respiratory infections in children | NA | BeFree | Detail | |
<0.001 | Congenital Abnormality | NA | BeFree | Detail | |
0.005 | Spontaneous abortion | NA | GAD | Detail | |
0.005 | Abortion, Habitual | NA | GAD | Detail | |
0.001 | Abscess | NA | BeFree | Detail | |
0.006 | Acidosis, Lactic | NA | BeFree,GAD,LHGDN | Detail | |
0.011 | acquired immunodeficiency syndrome | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Acute alcoholic liver disease | NA | BeFree | Detail | |
<0.001 | Acute Disease | NA | BeFree | Detail | |
0.002 | acute pancreatitis | After 7 days the serum concentrations of IL-10 were higher in the EA group than ... | BeFree | 25520280 | Detail |
0.014 | adenocarcinoma | NA | BeFree,GAD,LHGDN | Detail | |
0.006 | adenoma | NA | BeFree,GAD,LHGDN | Detail | |
0.003 | Adnexal Diseases | NA | BeFree,LHGDN | Detail | |
0.003 | agammaglobulinemia | NA | LHGDN | Detail | |
0.002 | Albuminuria | NA | GAD | Detail | |
0.006 | Alcoholic Intoxication, Chronic | NA | BeFree,GAD | Detail | |
0.005 | Alveolar Bone Loss | NA | GAD,LHGDN | Detail | |
0.002 | extrinsic allergic alveolitis | NA | GAD | Detail | |
0.039 | Alzheimer's disease | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | amyotrophic lateral sclerosis | NA | BeFree | Detail | |
0.009 | anemia | NA | BeFree,GAD,LHGDN | Detail | |
0.004 | aplastic anemia | NA | BeFree,LHGDN | Detail | |
<0.001 | Cooley's anemia | NA | BeFree | Detail | |
0.003 | autoimmune hemolytic anemia | NA | LHGDN | Detail | |
<0.001 | Aneurysm | NA | BeFree | Detail | |
0.002 | Angina Pectoris | NA | GAD | Detail | |
0.001 | Angina, Unstable | NA | BeFree | Detail | |
0.003 | Fabry disease | NA | BeFree,GAD | Detail | |
<0.001 | anorexia nervosa | NA | BeFree | Detail | |
0.003 | Anoxia | NA | LHGDN | Detail | |
0.001 | aortic aneurysm | NA | BeFree | Detail | |
0.002 | Aortic Rupture | NA | GAD | Detail | |
<0.001 | aortic valve insufficiency | NA | BeFree | Detail | |
0.120 | appendicitis | NA | CTD_human | Detail | |
0.006 | arteriosclerosis | Our data identify a novel role for FoxO1 in regulating IL-10 secretion during cl... | BeFree,GAD | 25420919 | Detail |
0.006 | arteriosclerosis | Association of interleukin-10 promoter region polymorphisms with risk factors of... | BeFree,GAD | 25421362 | Detail |
0.006 | arteriosclerosis | Atorvastatin treatment increased the percentage and inhibitory ability of nTregs... | BeFree,GAD | 25740578 | Detail |
0.022 | arthritis | Our data identify a novel role for FoxO1 in regulating IL-10 secretion during cl... | BeFree,GAD,LHGDN | 25420919 | Detail |
0.003 | Arthritis, Psoriatic | A direct causal role for increased serum IL-10 in inducing the observed changes ... | BeFree,GAD | 25670364 | Detail |
0.007 | aspergillosis | NA | BeFree,GAD | Detail | |
<0.001 | Aspergillosis, Allergic Bronchopulmonary | IL-10 protein levels were significantly lower in the ABPA and CCPA groups, compa... | BeFree | 25193981 | Detail |
0.023 | atherosclerosis | Our data identify a novel role for FoxO1 in regulating IL-10 secretion during cl... | BeFree,GAD,LHGDN | 25420919 | Detail |
0.023 | atherosclerosis | Association of interleukin-10 promoter region polymorphisms with risk factors of... | BeFree,GAD,LHGDN | 25421362 | Detail |
0.023 | atherosclerosis | Atorvastatin treatment increased the percentage and inhibitory ability of nTregs... | BeFree,GAD,LHGDN | 25740578 | Detail |
0.005 | atrial fibrillation | NA | GAD | Detail | |
0.120 | autistic disorder | NA | CTD_human | Detail | |
0.018 | Autoimmune Diseases | IL-10, IL-12 and IL-17F as inflammatory cytokines might be an important function... | BeFree,GAD,LHGDN | 25159155 | Detail |
0.018 | Autoimmune Diseases | IL-10 is elevated in the serum and tissues of patients with systemic lupus eryth... | BeFree,GAD,LHGDN | 25187566 | Detail |
0.018 | Autoimmune Diseases | The cytokines IL-6 and IL-10 are produced by cells of the adaptive and innate ar... | BeFree,GAD,LHGDN | 25794663 | Detail |
<0.001 | Melanoma, B16 | NA | BeFree | Detail | |
0.005 | Bacteremia | NA | BeFree,GAD | Detail | |
0.004 | Bacterial Infections | NA | BeFree,LHGDN | Detail | |
<0.001 | Pneumonia, Bacterial | NA | BeFree | Detail | |
0.002 | Barrett esophagus | NA | GAD | Detail | |
0.376 | Behcet Syndrome | Polymorphisms of interleukin 6 and interleukin 10 in Egyptian people with Behcet... | BeFree,CTD_human,GAD,GWASCAT,ORPHANET | 24703990 | Detail |
0.376 | Behcet Syndrome | Although we were not able to formally replicate the association with IL10 and IL... | BeFree,CTD_human,GAD,GWASCAT,ORPHANET | 25940109 | Detail |
0.376 | Behcet Syndrome | Behçet's disease (BD) is an immune-mediated and complex disease which has been a... | BeFree,CTD_human,GAD,GWASCAT,ORPHANET | 26005883 | Detail |
0.376 | Behcet Syndrome | We tested 14 single-nucleotide polymorphisms (SNPs) in 13 genomic loci (excludin... | BeFree,CTD_human,GAD,GWASCAT,ORPHANET | 26097239 | Detail |
<0.001 | Benign Ovarian Neoplasm | NA | BeFree | Detail | |
0.002 | Biliary Tract Neoplasm | NA | GAD | Detail | |
0.002 | bird fancier's lung | NA | GAD | Detail | |
0.008 | Malignant neoplasm of urinary bladder | NA | BeFree,GAD | Detail | |
0.002 | blastomycosis | NA | GAD | Detail | |
<0.001 | Bone Marrow Diseases | High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-... | BeFree | 25833232 | Detail |
0.001 | borderline personality disorder | NA | BeFree | Detail | |
0.005 | boutonneuse fever | NA | BeFree,GAD,LHGDN | Detail | |
0.035 | Malignant neoplasm of breast | LPS triggered increased expression of TLR4 downstream signaling pathway protein ... | BeFree,GAD | 25299052 | Detail |
0.035 | Malignant neoplasm of breast | NFKB1, NFKBIA, IL-8, IL-10, and TNF polymorphisms could serve as useful predicti... | BeFree,GAD | 25559835 | Detail |
<0.001 | bronchiolitis obliterans | NA | BeFree | Detail | |
0.007 | Bronchiolitis, Viral | NA | GAD | Detail | |
0.002 | bronchopneumonia | NA | GAD | Detail | |
0.006 | bronchopulmonary dysplasia | NA | BeFree,GAD,LHGDN | Detail | |
0.016 | brucellosis | NA | BeFree,GAD,LHGDN | Detail | |
0.004 | Burkitt lymphoma | NA | BeFree,LHGDN | Detail | |
0.009 | Cachexia | NA | BeFree,GAD | Detail | |
0.002 | candidiasis | NA | GAD | Detail | |
0.003 | Candidiasis, Chronic Mucocutaneous | NA | BeFree,LHGDN | Detail | |
0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of skin | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of thyroid | NA | BeFree | Detail | |
0.002 | basal cell carcinoma | NA | GAD | Detail | |
0.123 | Non-small cell lung carcinoma | NA | BeFree,CTD_human | Detail | |
0.002 | Carcinoma, Papillary | NA | GAD | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NA | DisGeNET | Detail |
Determination of IL-10 salivary concentration enabled us to distinguish patients with OSCC from heal... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Interleukin-10 gene -1082 G/A polymorphism in cervical cancer and cervical intraepithelial neoplasia... | DisGeNET | Detail |
IL-10 polymorphisms play a role in cervical cancer development and that GTC haplotype, which is clos... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Significant roles played by IL-10 in Chlamydia infections. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The combination of oral delivery of bioencapsulated FIX and intravenous replacement therapy induced ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Furthermore, blocking inflammasome activation with caspase-1 inhibitor in vivo significantly amelior... | DisGeNET | Detail |
Predictive validity and immune cell involvement in the pathogenesis of piroxicam-accelerated colitis... | DisGeNET | Detail |
Mice transferred with IL-10 KO cells received diets with or without food antigens, and the developme... | DisGeNET | Detail |
Mesenteric lymph node (MesLN) T cells were isolated from PAC IL-10 (-/-) mice and stimulated with IL... | DisGeNET | Detail |
Oral administration of B2 DNA beads significantly improved body weight, reduced colon injury, and su... | DisGeNET | Detail |
PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner. | DisGeNET | Detail |
Serotonin (5-HT) release and serotonin reuptake transporter (5-HTT) expression have been reported to... | DisGeNET | Detail |
SEW2871 treatment protects from colitis in IL-10(-/-) mice through reduced epithelial cell apoptosis... | DisGeNET | Detail |
Butein ameliorated colitis in IL-10(-/-) mice by regulating IL-6/STAT3 and MMP-9 activation. | DisGeNET | Detail |
Finally, abrogation of cellulose production reduced NC101 induction of colitis when NC101 was monoas... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Association of promoter genetic variants in interleukin-10 and Kawasaki disease with coronary artery... | DisGeNET | Detail |
We found that both clarithromycin and dexamethasone up-regulated the production of anti-inflammatory... | DisGeNET | Detail |
Increasing evidence indicates that IL-10 plays an important role in both the onset and development o... | DisGeNET | Detail |
The interleukin-10 knockout (IL-10 KO) mouse is a well-established murine model of IBD which develop... | DisGeNET | Detail |
Pro-inflammatory alleles of three cytokine genotypes, IL-8, IL-10 and IL-1β, appear to be associated... | DisGeNET | Detail |
NA | DisGeNET | Detail |
The allelic as well as genotypic frequencies of TNF-α and IL-10 did not significantly differ between... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In the present study, the association between IL-12B, IL-10 and TNF-α gene polymorphisms and dengue ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The results revealed that the DM1-preventing function was in part caused by a reduction in the pro-i... | DisGeNET | Detail |
Likewise, healthy individuals showed increased frequencies of both CD40(+) and IL-10(+) B cells comp... | DisGeNET | Detail |
T cells secreting the cytokines IFN-γ and IL-10 in response to seven peptides known to elicit T cell... | DisGeNET | Detail |
Association between interleukin 10 gene polymorphisms and risk of type 2 diabetes mellitus in a Chin... | DisGeNET | Detail |
TLR3 and downstream anti-inflammatory factors (IRF-3, INF-β and IL-10) were significantly down-regul... | DisGeNET | Detail |
Our findings suggest that TGF-β1 and IL-10 polymorphisms are involved in complications and comorbidi... | DisGeNET | Detail |
Our results indicate that 11 genetic variants within or near VEGFA, CCR5, CCL2, IL-1, MMP9, EPO, IL-... | DisGeNET | Detail |
Interleukin-10-1082A/G polymorphism and diabetic nephropathy: a meta-analysis. | DisGeNET | Detail |
Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codon 25C/G polymorphism... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Meta-analysis of associations between interleukin-10 polymorphisms and susceptibility to pre-eclamps... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Increased concentration of interferon lambda-3, interferon beta and interleukin-10 in the cerebrospi... | DisGeNET | Detail |
By using IL-10 reporter mice, we found that plasmablasts in the draining lymph nodes (dLNs), but not... | DisGeNET | Detail |
In this study, 14 single nucleotide variants (SNVs) in genes coding for interleukin-1β, interleukin-... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Piroxicam administration is a method for induction of enterocolitis in interleukin-10 knockout (IL-1... | DisGeNET | Detail |
We found that both clarithromycin and dexamethasone up-regulated the production of anti-inflammatory... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
By contrast, the percentage of peripheral IL‑10‑producing Bregs (B10s) significantly increased in pa... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
FOXP3 mRNA levels were correlated positively with TGF-β1 and IL-10 mRNA levels in the H pylori(+) ga... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The overall findings of the study support the correlation of high-producer TNF-α genotypes combined ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In addition, expression levels of anti-inflammatory cytokine IL-10 was down-regulated significantly ... | DisGeNET | Detail |
Association between IL-10 gene promoter polymorphism and hepatitis B viral infection in an Egyptian ... | DisGeNET | Detail |
Association of interleukin-10 with hepatitis B virus (HBV) mediated disease progression in Indian po... | DisGeNET | Detail |
Circulating CD56dim natural killer cells and CD56+ T cells that produce interferon-γ or interleukin-... | DisGeNET | Detail |
Association of the IFNAR1-17470 and IL-10-592 cytokine variants with susceptibility to chronic hepat... | DisGeNET | Detail |
The start of immune-clearance phase, age at HBeAg seroconversion, and serum IL-10 and IL-12 levels a... | DisGeNET | Detail |
Influence of IL10 gene polymorphisms on the severity of liver fibrosis and susceptibility to liver c... | DisGeNET | Detail |
The presence of low producing IL-10-1082A and -592A alleles and their containing genetic variants pr... | DisGeNET | Detail |
A -819 C/T polymorphism in the interleukin-10 promoter is associated with persistent HBV infection, ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
In addition, the OR of the patients with CHB having the IL-10-592 C/C variant developing chronic hep... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Although we found a possible association between IL-10 promoter polymorphisms and HCV infection, cer... | DisGeNET | Detail |
We investigated the association between hepatitis C virus (HCV) genotypes and host cytokine gene pol... | DisGeNET | Detail |
Relationships between interleukin-12B and interleukin-10 gene polymorphisms and hepatitis C in Chine... | DisGeNET | Detail |
This study investigated genetic variability in the IL-10 gene promoter between patients infected wit... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Reduced levels of let-7 miRNAs have been linked to higher levels of IL-10, again with potential path... | DisGeNET | Detail |
Influence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV serostatus among in... | DisGeNET | Detail |
Polymorphisms in the IFNγ, IL-10, and TGFβ genes may be associated with HIV-1 infection. | DisGeNET | Detail |
This study was undertaken to investigate the possible association of genetic polymorphisms of 3' unt... | DisGeNET | Detail |
NA | DisGeNET | Detail |
This study was undertaken to investigate the possible association of genetic polymorphisms of 3' unt... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Distinct role of FoxO1 in M-CSF- and GM-CSF-differentiated macrophages contributes LPS-mediated IL-1... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Hypertension was associated with the CC genotype and C allele for IL-10 -592C/A polymorphism (p = 0.... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Targeting IL-10 in auto-immune diseases. | DisGeNET | Detail |
Here we generated the IL10/Nox1dKO mouse model which combines immune dysfunction (IL-10 deficiency) ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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In this study, we investigated the role of inflammasome activation in the development of chronic int... | DisGeNET | Detail |
Very early-onset inflammatory bowel disease (IBD) in infancy is a different disease entity from adul... | DisGeNET | Detail |
In conclusion, reference drugs with known efficacy in severe inflammatory bowel disease were efficac... | DisGeNET | Detail |
Novel de novo mutations of the interleukin-10 receptor gene lead to infantile onset inflammatory bow... | DisGeNET | Detail |
The associations in IL10 and IL18R1 are shared with inflammatory bowel disease, suggesting common et... | DisGeNET | Detail |
The effect of turmeric (Curcuma longa) extract on the functionality of the solute carrier protein 22... | DisGeNET | Detail |
Human adipose-derived stem cells attenuate inflammatory bowel disease in IL-10 knockout mice. | DisGeNET | Detail |
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In this study, we first reproduced the recovery-recurrence periods observed in IBS-patients in a new... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codon 25C/G polymorphism... | DisGeNET | Detail |
Single-nucleotide polymorphisms (SNPs) in the IL-10 gene (-1082 [rs1800896], -819 [rs3021097], and -... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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The redirection of the immune response elicited against the LiPABP family (from IL-10 towards IFN-γ ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
IL10 Variant g.5311A Is Associated with Visceral Leishmaniasis in Indian Population. | DisGeNET | Detail |
Association of TNF-α-(308(GG)), IL-10(-819(TT)), IL-10(-1082(GG)) and IL-1R1(+1970(CC)) genotypes wi... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
IPI-145 potently inhibits the CD40L/IL-2/IL-10 induced proliferation of CLL cells with an IC50 in su... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Herein, we applied a novel DC-based vaccine (i.e., DC loaded with leukemia antigens that have been t... | DisGeNET | Detail |
Interleukin-10 polymorphisms associated with susceptibility to acute myeloid leukemia. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Moreover, the IL-10 protein and mRNA levels in peripheral blood mono nuclear cells (PBMCs) showed a ... | DisGeNET | Detail |
Influence of IL10 gene polymorphisms on the severity of liver fibrosis and susceptibility to liver c... | DisGeNET | Detail |
Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis in Taiwanese patients... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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NA | DisGeNET | Detail |
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Pro-inflammatory alleles of three cytokine genotypes, IL-8, IL-10 and IL-1β, appear to be associated... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Analysis of mRNA transcripts of unstimulated lung CD4+ T cell among all subjects identified two dist... | DisGeNET | Detail |
IL-10 disrupts the Brd4-docking sites to inhibit LPS-induced CXCL8 and TNF-α expression in monocytes... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling. | DisGeNET | Detail |
Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling. | DisGeNET | Detail |
Increasing evidence indicates that IL-10 plays an important role in both the onset and development o... | DisGeNET | Detail |
Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling. | DisGeNET | Detail |
STAT4 and IL10 confirm their association with SLE. | DisGeNET | Detail |
Lack of association between interleukin-10, transforming growth factor-beta gene polymorphisms and j... | DisGeNET | Detail |
The cytokines IL-6 and IL-10 are produced by cells of the adaptive and innate arms of the immune sys... | DisGeNET | Detail |
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The interleukin-10-1082A>G polymorphism and lymphoma risk: a meta-analysis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Analysis of interleukin-10 promoter single nucleotide polymorphisms and risk of non-Hodgkin lymphoma... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In addition, the aqueous humor levels of IL-10 and IL-12 decreased with increasing the severity of M... | DisGeNET | Detail |
IL10A genotypic association with decreased IL-10 circulating levels in malaria infected individuals ... | DisGeNET | Detail |
Proinflammatory responses and higher IL-10 production by T cells correlate with protection against m... | DisGeNET | Detail |
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NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The allele flip observed in IL-10 and gastric cancer appears to reflect allelic heterogeneity, simil... | DisGeNET | Detail |
Based on 40 studies and 18950 participants, we found the variant IL-10 -1082G allele significantly i... | DisGeNET | Detail |
Effects of interleukin-10 polymorphisms and smoking on the risk of gastric cancer in Taiwan. | DisGeNET | Detail |
Interleukin-10 gene -592C>A polymorphism and susceptibility to gastric cancer. | DisGeNET | Detail |
Clinical study on gastric cancer susceptibility genes IL-10-1082 and TNF-α. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Role of IL-10 and TGF-β in melanoma. | DisGeNET | Detail |
We discovered novel associations of IL10 with melanoma survival at 1q32.1, suggesting this locus sho... | DisGeNET | Detail |
NA | DisGeNET | Detail |
There was an increased serum IFNβ and a tendency for increased serum IL-10 in meningitis patients. | DisGeNET | Detail |
NA | DisGeNET | Detail |
IL-10 immunodepletion from meningococcal sepsis plasma induces extensive changes in gene expression ... | DisGeNET | Detail |
IL-10, IFNβ and IFNλ3 were up-regulated in csf, with IFNλ3 level higher in patients with the milder ... | DisGeNET | Detail |
Adoptive transfer of B-1a cells into HFD-fed B cell-deficient mice rapidly improves insulin resistan... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Present findings indicate that IL-10 gene variants may be considered as genetic risk factors for MCT... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Association of promoter genetic variants in interleukin-10 and Kawasaki disease with coronary artery... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Increasing evidence indicates that IL-10 plays an important role in both the onset and development o... | DisGeNET | Detail |
We assessed the relationship of stimulated PBMC-produced IFN-γ, TNF-α, IL-4 and IL-10 in modulating ... | DisGeNET | Detail |
Seeking balance: Potentiation and inhibition of multiple sclerosis autoimmune responses by IL-6 and ... | DisGeNET | Detail |
Grape seed extract prevents skeletal muscle wasting in interleukin 10 knockout mice. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Gram-positive bacterial and fungal infections did not cause a marked increase in IL-6 or IL- 10 leve... | DisGeNET | Detail |
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These results suggest that tested SNPs associated with differential production of IL-1 female and IL... | DisGeNET | Detail |
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The expression of LEP, LEPR, IGF1 and IL10 in obesity and the relationship with microRNAs. | DisGeNET | Detail |
B-1a cells are reduced in frequency in obese high-fat diet (HFD)-fed mice, and EGFP interleukin-10 (... | DisGeNET | Detail |
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Similarly, the TNFα -1031 and -863 minor alleles were associated with an increased risk of hand OA o... | DisGeNET | Detail |
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High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic vi... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Contrary to this, TNF-α levels were unchanged upon MAP stimulation regardless of NOD2 genotype and M... | DisGeNET | Detail |
Interleukin-10-1082A/G and -592C/A polymorphisms with risk of Parkinson's disease: a meta-analysis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Associations of three well-characterized polymorphisms in the IL-6 and IL-10 genes with pneumonia: a... | DisGeNET | Detail |
Interestingly, we observed that all BI patients with high frequency of IL-10(+) B cells on day 1 dis... | DisGeNET | Detail |
The studies involved the following polymorphisms: TNF-α -308G > A, TNF-α -805C>T, TNF-α -1031 T>C, I... | DisGeNET | Detail |
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Increasing evidence indicates that IL-10 plays an important role in both the onset and development o... | DisGeNET | Detail |
Psoriasis-specific genes were important regulators of glucose and lipid metabolism, epidermal differ... | DisGeNET | Detail |
Novel mutations in IL-10 promoter region -377 (C>T), -150 (C>A) and their association with psoriasis... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Analysis of mRNA transcripts of unstimulated lung CD4+ T cell among all subjects identified two dist... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Association of SNP (-G1082A) IL-10 with increase in severity of periportal fibrosis in schistosomias... | DisGeNET | Detail |
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Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but n... | DisGeNET | Detail |
Association between interleukin-10 polymorphisms and sepsis: a meta-analysis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic vi... | DisGeNET | Detail |
Whole body hyperthermia treatment increases interleukin 10 and toll-like receptor 4 expression in pa... | DisGeNET | Detail |
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When early stage and late stage CSF cytokines were compared, IL-10 and IL-6 were up regulated in lat... | DisGeNET | Detail |
Interleukin (IL)-6 and IL-10 Are Up Regulated in Late Stage Trypanosoma brucei rhodesiense Sleeping ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Independent and joint effects of the IL-6 and IL-10 gene polymorphisms in pulmonary tuberculosis amo... | DisGeNET | Detail |
Moreover, the polymorphisms at IFN-γ -874 and IL10 - 1082 were associated with protein levels of IFN... | DisGeNET | Detail |
NA | DisGeNET | Detail |
IL-10 G-1082A gene polymorphism and susceptibility to upper respiratory tract infection among endura... | DisGeNET | Detail |
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Whereas IL-10 is important in terminating pro-inflammatory and antiviral immune responses, the prese... | DisGeNET | Detail |
This study investigated genetic variability in the IL-10 gene promoter between patients infected wit... | DisGeNET | Detail |
The combination of tumour necrosis factor-α -308A and interleukin-10 -1082G gene polymorphisms and i... | DisGeNET | Detail |
Isolated PBMCs from O. volvulus-infected individuals (164 MF(+) and 46 a-MF) and non-infected volunt... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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We hypothesized that DLBCLs depend for their proliferation and survival on IL10-STAT3 signaling and ... | DisGeNET | Detail |
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These findings provide the first insights into the BZ-regulated TGF-β1 and IL-10 expression in CTCL ... | DisGeNET | Detail |
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By contrast, the percentage of peripheral IL‑10‑producing Bregs (B10s) significantly increased in pa... | DisGeNET | Detail |
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TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer in Taiwanese. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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The possible role of IL-10 as a therapy in allergic asthma has already been suggested, but the diver... | DisGeNET | Detail |
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Hypertrophic scar fibroblasts (HSFs) were treated with rhIL10-RGD, and the fibrosis-related protein ... | DisGeNET | Detail |
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TNF-α, TNF-β and IL-10 gene polymorphism and association with oral lichen planus risk in Saudi patie... | DisGeNET | Detail |
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Interleukin-10 gene -1082 G/A polymorphism in cervical cancer and cervical intraepithelial neoplasia... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer in Taiwanese. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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IL-10 expression resulted in increased Aβ accumulation and impaired memory in APP mice. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IFN-γ) of T cells co-c... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Influence of IL10 gene polymorphisms on the severity of liver fibrosis and susceptibility to liver c... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL deficiency. | DisGeNET | Detail |
Interleukin-10 (IL-10) promoter genotypes are associated with lung cancer risk in Taiwan males and s... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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No association was found between C. difficile carriage and chemotherapy regimen, antibiotic drug use... | DisGeNET | Detail |
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Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but n... | DisGeNET | Detail |
Association between interleukin-10 polymorphisms and sepsis: a meta-analysis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Several studies have reported an association between interleukin 10 (IL-10) variant polymorphisms an... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Variations in the TNFα gene and their interactions with the IL4R and IL10 genes in relation to hand ... | DisGeNET | Detail |
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Association of -1082 interleukin-10 gene polymorphism in Peruvian adults with chronic periodontitis. | DisGeNET | Detail |
In this study, we investigated the role of inflammasome activation in the development of chronic int... | DisGeNET | Detail |
Chronic colitis was induced in interleukin 10-deficient mice. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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A recent genome-wide association study discovered that two polymorphisms, interferon (IFN) alpha rec... | DisGeNET | Detail |
In addition, the aqueous humor levels of IL-10 and IL-12 decreased with increasing the severity of M... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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In conclusion, although IL-10 concentration and Treg percentage were increased, their contribution t... | DisGeNET | Detail |
Since the immune status of the tumor microenvironment could play a role in the history of disease, w... | DisGeNET | Detail |
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There was a significant correlation between sHLA-G and IL-10 expression (r=0.353, P=0.006) in patien... | DisGeNET | Detail |
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Interleukin-10 gene -1082 G/A polymorphism in cervical cancer and cervical intraepithelial neoplasia... | DisGeNET | Detail |
Association of IL-10 GTC haplotype with serum level and HPV infection in the development of cervical... | DisGeNET | Detail |
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Aspirin desensitization was reported to decrease the levels of CD4⁺ T cell-derived cytokines, includ... | DisGeNET | Detail |
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Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IFN-γ) of T cells co-c... | DisGeNET | Detail |
The present study indicated the DQB1*02 or DQB1*0603 alleles are related to IBS-D occurrence in Guan... | DisGeNET | Detail |
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Hp GE-driven enhancement of lymphocyte cytotoxic activity was associated with the expansion of CD3(-... | DisGeNET | Detail |
SNPs in several genes were associated with increased chronic respiratory morbidity (interleukin 10 (... | DisGeNET | Detail |
Conversely, murine studies indicate that the combined actions of regulatory factors such as CD4 regu... | DisGeNET | Detail |
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We conclude that promoter genetic variants of IL-18 and IL-10 with various modes of tobacco exposure... | DisGeNET | Detail |
The present study investigates the role of variations in the promoter regions of IL-18 and IL-10 (an... | DisGeNET | Detail |
Association of IL-1β and IL-10 Polymorphisms with Prostate Cancer Risk and Grade of Disease in Easte... | DisGeNET | Detail |
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The p values for IL 10 -819 C>T and IL 10 -1082 G>A were respectively 0.031 and 0.026 in healthy vol... | DisGeNET | Detail |
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In the study we investigated the levels of IL-35 as well as its prospective role in immune thrombocy... | DisGeNET | Detail |
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Variations in the TNFα gene and their interactions with the IL4R and IL10 genes in relation to hand ... | DisGeNET | Detail |
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Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling. | DisGeNET | Detail |
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The low concentrations of IL-10 may suggest an anti-inflammatory modulation in postmenopausal women ... | DisGeNET | Detail |
Our observations that IL-10 has an unexpected negative effect on Aβ proteostasis and cognition in AP... | DisGeNET | Detail |
Role of proinflammatory cytokines (interferon gamma) and anti-inflammatory cytokine (interleukin-10)... | DisGeNET | Detail |
Myeloid-derived suppressor cells regulate immune response in patients with chronic hepatitis B virus... | DisGeNET | Detail |
Association of the IFNAR1-17470 and IL-10-592 cytokine variants with susceptibility to chronic hepat... | DisGeNET | Detail |
Previous studies about the association of the interleukin-10 (IL-10) polymorphisms with the progress... | DisGeNET | Detail |
Haplotype analysis of interleukin-10 gene promoter polymorphisms in chronic hepatitis C infection: a... | DisGeNET | Detail |
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By contrast, the percentage of peripheral IL‑10‑producing Bregs (B10s) significantly increased in pa... | DisGeNET | Detail |
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In addition, the aqueous humor levels of IL-10 and IL-12 decreased with increasing the severity of M... | DisGeNET | Detail |
Interleukin-10 (IL10) is a pleiotropic cytokine produced by macrophages which can suppress and stimu... | DisGeNET | Detail |
Interleukin-10 (IL-10) is an immunosuppressive cytokine involved in carcinogenesis via immune escape... | DisGeNET | Detail |
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Pro-(IL-18) and Anti-(IL-10) Inflammatory Promoter Genetic Variants (Intrinsic Factors) with Tobacco... | DisGeNET | Detail |
Functional genetic variability at promoters of pro-(IL-18) and anti-(IL-10) inflammatory affects the... | DisGeNET | Detail |
Association of IL-1β and IL-10 Polymorphisms with Prostate Cancer Risk and Grade of Disease in Easte... | DisGeNET | Detail |
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LPS triggered increased expression of TLR4 downstream signaling pathway protein myeloid differentiat... | DisGeNET | Detail |
NFKB1, NFKBIA, IL-8, IL-10, and TNF polymorphisms could serve as useful predictive biomarkers for br... | DisGeNET | Detail |
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Interleukin-10 (IL-10) promoter genotypes are associated with lung cancer risk in Taiwan males and s... | DisGeNET | Detail |
The -1082A>G polymorphism in promoter region of interleukin-10 and risk of digestive cancer: a meta-... | DisGeNET | Detail |
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The allele flip observed in IL-10 and gastric cancer appears to reflect allelic heterogeneity, simil... | DisGeNET | Detail |
Based on 40 studies and 18950 participants, we found the variant IL-10 -1082G allele significantly i... | DisGeNET | Detail |
Effects of interleukin-10 polymorphisms and smoking on the risk of gastric cancer in Taiwan. | DisGeNET | Detail |
Interleukin-10 gene -592C>A polymorphism and susceptibility to gastric cancer. | DisGeNET | Detail |
Clinical study on gastric cancer susceptibility genes IL-10-1082 and TNF-α. | DisGeNET | Detail |
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Here, we investigated the roles of inflammasomes [absent in melanoma 2 (AIM2); NLR family, CARD doma... | DisGeNET | Detail |
Our recent studies suggest that MS peripheral blood B cells secrete higher quantities of IL-6 and le... | DisGeNET | Detail |
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Together, these results demonstrate that H. pylori infection induces IL-10 secretion in DCs, which a... | DisGeNET | Detail |
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Interleukin-10 affects maternal intravascular inflammation, as well as endothelial dysfunction. | DisGeNET | Detail |
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Association between interleukin-10 promoter gene polymorphisms and acute graft-versus-host disease a... | DisGeNET | Detail |
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Role of cytokine gene (interferon-γ, transforming growth factor-β1, tumor necrosis factor-α, interle... | DisGeNET | Detail |
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We aimed to investigate the association of inflammation-related genes such as IL-10, IL-6 and IL-1B ... | DisGeNET | Detail |
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APL-2, an altered peptide ligand derived from heat-shock protein 60, induces interleukin-10 in perip... | DisGeNET | Detail |
Pre-clinical Vac-PSG1a treatment suppressed the Th1- and Th17-type-specific responses, leading to an... | DisGeNET | Detail |
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In conclusion, although IL-10 concentration and Treg percentage were increased, their contribution t... | DisGeNET | Detail |
Since the immune status of the tumor microenvironment could play a role in the history of disease, w... | DisGeNET | Detail |
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Significantly, AA homozygous genotype was dominant in chronic hepatitis B cases in IFN-γ+874 and IL-... | DisGeNET | Detail |
However, the IL-10-592 and -819 genotypes were not found significant difference both between the ant... | DisGeNET | Detail |
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Several studies have reported an association between interleukin 10 (IL-10) variant polymorphisms an... | DisGeNET | Detail |
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SNPs in several genes were associated with increased chronic respiratory morbidity (interleukin 10 (... | DisGeNET | Detail |
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At first recruitment of women with LSIL (100 cases), IL-10 mRNA and cytokine in HPV positive group (... | DisGeNET | Detail |
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We found that both clarithromycin and dexamethasone up-regulated the production of anti-inflammatory... | DisGeNET | Detail |
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IL-10/Janus kinase/signal transducer and activator of transcription 3 signaling dysregulates Bim exp... | DisGeNET | Detail |
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For TLR1, increased interleukin 10 responses to C. burnetii in individuals carrying the risk allele ... | DisGeNET | Detail |
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These results indicate that rhIL10-RGD has anti-fibrosis effects and can potentially be used to trea... | DisGeNET | Detail |
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Our results suggest that mutations that disrupt the interactions of IL-10 with its receptors (IL-10R... | DisGeNET | Detail |
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Increasing evidence indicates that IL-10 plays an important role in both the onset and development o... | DisGeNET | Detail |
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In this study, 14 single nucleotide variants (SNVs) in genes coding for interleukin-1β, interleukin-... | DisGeNET | Detail |
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Moreover, the IL-10 protein and mRNA levels in peripheral blood mono nuclear cells (PBMCs) showed a ... | DisGeNET | Detail |
Previous studies about the association of the interleukin-10 (IL-10) polymorphisms with the progress... | DisGeNET | Detail |
We found that both clarithromycin and dexamethasone up-regulated the production of anti-inflammatory... | DisGeNET | Detail |
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Herein, we describe a protocol for in vitro synthesis of small interfering RNA against IDO and other... | DisGeNET | Detail |
The stimulation of peripheral blood mononuclear cells with r-LdODC up-regulated IL-10 production but... | DisGeNET | Detail |
The combination of oral delivery of bioencapsulated FIX and intravenous replacement therapy induced ... | DisGeNET | Detail |
Our data support the possibility that IL-10 gene polymorphisms may be related with CAA development o... | DisGeNET | Detail |
The combination of tumour necrosis factor-α -308A and interleukin-10 -1082G gene polymorphisms and i... | DisGeNET | Detail |
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It was also noted that high levels of IL-10, TGF-β1 and CCL17 were observed in MPE when compared to ... | DisGeNET | Detail |
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The present study was designed to evaluate the impact of IL-10 (-819/-592) genotypes, haplotypes, mR... | DisGeNET | Detail |
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In vitro HDM challenge presents concordant patterns with in vivo findings: 1) increase of Th2 and Th... | DisGeNET | Detail |
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Real-time polymerase chain reaction analysis confirmed the significant upregulation of interleukin (... | DisGeNET | Detail |
We aimed to investigate the association of inflammation-related genes such as IL-10, IL-6 and IL-1B ... | DisGeNET | Detail |
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We found that both clarithromycin and dexamethasone up-regulated the production of anti-inflammatory... | DisGeNET | Detail |
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Associations of three well-characterized polymorphisms in the IL-6 and IL-10 genes with pneumonia: a... | DisGeNET | Detail |
Interestingly, we observed that all BI patients with high frequency of IL-10(+) B cells on day 1 dis... | DisGeNET | Detail |
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After 7 days the serum concentrations of IL-10 were higher in the EA group than in the control group... | DisGeNET | Detail |
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Our data identify a novel role for FoxO1 in regulating IL-10 secretion during classic activation and... | DisGeNET | Detail |
Association of interleukin-10 promoter region polymorphisms with risk factors of Atherosclerosis. | DisGeNET | Detail |
Atorvastatin treatment increased the percentage and inhibitory ability of nTregs, decreased serum IF... | DisGeNET | Detail |
Our data identify a novel role for FoxO1 in regulating IL-10 secretion during classic activation and... | DisGeNET | Detail |
A direct causal role for increased serum IL-10 in inducing the observed changes in lipoproteins was ... | DisGeNET | Detail |
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IL-10 protein levels were significantly lower in the ABPA and CCPA groups, compared with the healthy... | DisGeNET | Detail |
Our data identify a novel role for FoxO1 in regulating IL-10 secretion during classic activation and... | DisGeNET | Detail |
Association of interleukin-10 promoter region polymorphisms with risk factors of Atherosclerosis. | DisGeNET | Detail |
Atorvastatin treatment increased the percentage and inhibitory ability of nTregs, decreased serum IF... | DisGeNET | Detail |
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IL-10, IL-12 and IL-17F as inflammatory cytokines might be an important functional candidate genes f... | DisGeNET | Detail |
IL-10 is elevated in the serum and tissues of patients with systemic lupus erythematosus (SLE), an a... | DisGeNET | Detail |
The cytokines IL-6 and IL-10 are produced by cells of the adaptive and innate arms of the immune sys... | DisGeNET | Detail |
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Polymorphisms of interleukin 6 and interleukin 10 in Egyptian people with Behcet's disease. | DisGeNET | Detail |
Although we were not able to formally replicate the association with IL10 and IL23R-IL12RB2, we do r... | DisGeNET | Detail |
Behçet's disease (BD) is an immune-mediated and complex disease which has been associated with HLA c... | DisGeNET | Detail |
We tested 14 single-nucleotide polymorphisms (SNPs) in 13 genomic loci (excluding the major histocom... | DisGeNET | Detail |
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High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic vi... | DisGeNET | Detail |
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LPS triggered increased expression of TLR4 downstream signaling pathway protein myeloid differentiat... | DisGeNET | Detail |
NFKB1, NFKBIA, IL-8, IL-10, and TNF polymorphisms could serve as useful predictive biomarkers for br... | DisGeNET | Detail |
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Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
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Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs3021097 dbSNP
- Genome
- hg19
- Position
- chr1:206,940,947-206,947,886
- Variant Type
- snv
Genome browser