Malaria, Vivax
Information
- Disease name
- Malaria, Vivax
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05096702 | Active, not recruiting | Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in Brazil | September 9, 2021 | September 9, 2023 | |
| NCT03797989 | Active, not recruiting | Early Phase 1 | VAC069: A Study of Blood-stage Controlled Human P. Vivax Infection | January 10, 2019 | December 31, 2022 |
| NCT05270265 | Active, not recruiting | Early Phase 1 | Safety and Immunogenicity of Pvs25-IMX313/Matrix-M1 Vaccine | February 9, 2022 | September 30, 2023 |
| NCT04079621 | Active, not recruiting | Phase 4 | Short Course Radical Cure of P. Vivax Malaria in Nepal | October 27, 2021 | March 31, 2024 |
| NCT04223674 | Active, not recruiting | N/A | Serological Screen and Treat Trial for Plasmodium Vivax | February 9, 2022 | December 30, 2023 |
| NCT01083095 | Completed | Early Phase 1 | Establishment of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers | January 2005 | December 2006 |
| NCT01213966 | Completed | Phase 2 | Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection | October 2010 | May 2012 |
| NCT01376167 | Completed | Phase 2 | Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse | April 24, 2014 | November 18, 2016 |
| NCT01928914 | Completed | Phase 1 | Tafenoquine Thorough QTc Study in Healthy Subjects | July 26, 2011 | June 4, 2012 |
| NCT00157885 | Completed | N/A | A Randomised Trial of Artekin and Artesunate & Amodiaquine for Uncomplicated Malaria in Timika, Papua, Indonesia. | July 2005 | December 2005 |
| NCT02216123 | Completed | Phase 3 | Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria | April 30, 2015 | November 4, 2016 |
| NCT02563496 | Completed | Phase 2 | A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria | February 6, 2017 | February 17, 2020 |
| NCT02658435 | Completed | Phase 1 | Assessment of Any Potential Retinal Effects of Tafenoquine (TQ) | February 2, 2016 | September 14, 2017 |
| NCT02691910 | Completed | Phase 2/Phase 3 | Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax Infection | August 2014 | September 2015 |
| NCT02751294 | Completed | Phase 1 | A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution | May 2016 | August 2016 |
| NCT02802501 | Completed | Phase 3 | Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria | April 8, 2018 | August 19, 2019 |
| NCT03208907 | Completed | Phase 3 | DHA-PQP vs Chloroquine and Primaquine for Radical Cure of Vivax Malaria in Brazil | July 5, 2018 | July 2, 2021 |
| NCT03307369 | Completed | A Retrospective Study of Severe Plasmodium Vivax | October 27, 2017 | July 15, 2020 | |
| NCT03377296 | Completed | N/A | Study of Controlled Human Plasmodium Vivax Infection | March 3, 2018 | April 13, 2023 |
| NCT03610399 | Completed | N/A | Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil | April 9, 2018 | March 12, 2019 |
| NCT04009096 | Completed | Phase 2 | VAC071: A Study to Assess Efficacy of the ChAd63/MVA PvDBP Vaccines | July 18, 2019 | July 7, 2022 |
| NCT02184637 | Completed | Phase 1 | A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate | July 31, 2014 | April 8, 2015 |
| NCT00486694 | Completed | Phase 2 | Artesunate Plus Sulfadoxine-Pyrimethamine Versus Chloroquine for Vivax Malaria | March 2004 | August 2004 |
| NCT00811096 | Completed | Phase 2 | Pilot Human Study of Tinidazole Efficacy For Radical Cure Of Plasmodium Vivax | November 2008 | April 2009 |
| NCT00951106 | Completed | N/A | Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian Amazon | January 1998 | August 2009 |
| NCT01081847 | Completed | Phase 1 | Safety and Immunogenicity Study of Plasmodium Vivax CS Derived Synthetic Peptides Formulated in Two Adjuvants | July 2005 | April 2006 |
| NCT04709692 | Completed | Phase 2 | Efficacy of SJ733 in Adults With Uncomplicated Plasmodium Falciparum or Vivax Malaria | April 14, 2021 | April 15, 2022 |
| NCT05753150 | Completed | Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in Thailand | May 23, 2022 | October 1, 2023 | |
| NCT06036030 | Completed | Phase 2 | Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papua | January 11, 2019 | April 16, 2019 |
| NCT05690841 | Not yet recruiting | Phase 3 | FocaL Mass Drug Administration for Vivax Malaria Elimination | June 1, 2024 | May 1, 2027 |
| NCT05044637 | Recruiting | Phase 2 | Study to Evaluate Primaquine for Radical Cure of Uncomplicated Plasmodium Vivax Malaria in Children | August 26, 2021 | December 1, 2023 |
| NCT05058885 | Recruiting | Plasmodium Vivax Among Duffy Negative Population in Cameroon. | May 2, 2022 | June 30, 2024 | |
| NCT05788094 | Recruiting | Phase 4 | ACT vs CQ With Tafenoquine for P. Vivax Mono-infection | June 26, 2023 | August 31, 2025 |
| NCT05361486 | Recruiting | Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru | August 28, 2023 | October 31, 2024 | |
| NCT05540470 | Recruiting | N/A | Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield | September 12, 2022 | December 12, 2025 |
| NCT04411836 | Recruiting | Phase 3 | Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine | April 25, 2021 | September 30, 2024 |
| NCT03337152 | Terminated | Phase 4 | Assessing a Risk Model for G6PD Deficiency | May 7, 2018 | October 21, 2018 |
| NCT02110784 | Terminated | Phase 2 | Eurartesim® in Patients With Imported Uncomplicated Plasmodium Vivax Malaria | June 18, 2014 | April 30, 2017 |
| NCT04739917 | Unknown status | Phase 2 | Efficacy of a Synthetic Vaccine Derived From Plasmodium Vivax Circumsporozoite Protein (PvCS) in naïve and Semi-immune Volunteers | June 1, 2021 | December 1, 2022 |
| NCT04201431 | Unknown status | Phase 1/Phase 2 | Safety, Immunogenicity and Efficacy of the Blood-stage Plasmodium Vivax Malaria Vaccine Candidate PvDBPII in Matrix M1 | January 24, 2020 | August 2022 |
| NCT05232227 | Withdrawn | Phase 2/Phase 3 | Primaquine Double Dose for Radical Cure of Plasmodium Vivax in Colombia | January 20, 2023 | October 30, 2023 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D016780