sinusitis
Information
- Disease name
- sinusitis
- Disease ID
- DOID:0050127
- Description
- "A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip." [url:http\://en.wikipedia.org/wiki/sinusitis, url:http\://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&version=14.10d&code=C35024&ns=NCI_Thesaurus&key=1218436475&b=1&n=null]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02533206 | Active, not recruiting | N/A | Pilot Study of The EPIC Trial | August 2015 | December 2024 |
| NCT05865496 | Active, not recruiting | Phase 2 | A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps | June 30, 2023 | July 31, 2024 |
| NCT00004638 | Completed | N/A | Immunologic Aspects of the Pathogenesis of Chronic Sinusitis in Children | ||
| NCT00117611 | Completed | Phase 4 | Xolair in Patients With Chronic Sinusitis | July 2005 | January 2009 |
| NCT00132275 | Completed | N/A | Guidelines for Acute Sinusitis | November 2003 | August 2006 |
| NCT00174694 | Completed | Phase 4 | CHOOSE : Telithromycin, Acute Bacterial Sinusitis | November 2004 | |
| NCT00208065 | Completed | Phase 4 | Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers | May 2004 | November 2005 |
| NCT00232154 | Completed | Phase 2 | A Study To Measure The Level Of Drug In Nasal Tissue And Blood After Taking A Single 2g Dose Or 500mg Tablets For Up To | November 2005 | June 2006 |
| NCT00236522 | Completed | Phase 3 | A Comparison of the Safety and Efficacy of Two Different Regimens of Levofloxacin in the Treatment of Acute Bacterial Sinusitis(Sinus Infection) in Adults. | October 2002 | April 2004 |
| NCT00242437 | Completed | Phase 4 | Hemostatic Matrix in Endoscopic Sinus Surgery | October 2005 | February 2006 |
| NCT00245427 | Completed | N/A | Outcomes of Patients Not Responding to Antibiotics in the Community | December 2005 | March 2006 |
| NCT00249210 | Completed | Phase 3 | A Study of the Safety and Effectiveness of Levofloxacin Compared With Amoxicillin/Clavulanate Potassium in the Treatment of Adults With Rapid Onset of Severe Inflammation/Infection of the Sinuses | August 1993 | July 1994 |
| NCT00266474 | Completed | Prevalence of Chronic Rhinosinusitis in Cystic Fibrosis | December 2005 | September 2007 | |
| NCT00335309 | Completed | N/A | Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis | October 2005 | August 2013 |
| NCT00355160 | Completed | Non-Rhinologic Etiologies of Headaches and Facial Pain in Tertiary Care Setting | July 2006 | April 2009 | |
| NCT00367120 | Completed | Phase 4 | Zmax Compared to Augmentin in Sinusitis | June 2006 | February 2007 |
| NCT00368823 | Completed | Phase 3 | A Trial of Point of Care Information in Ambulatory Pediatrics | November 1999 | December 2003 |
| NCT00416182 | Completed | Phase 2 | Nasally Delivered Pulmozyme for Sinusitis in Cystic Fibrosis | December 2006 | June 2012 |
| NCT06016335 | Completed | N/A | MRI-based Synthetic CT Images of the Head and Neck | September 22, 2022 | September 12, 2023 |
| NCT00465530 | Completed | N/A | Comparing the Use of Saline or Saline Plus Gentamycin in Nasal Irrigation to Treat Chronic Sinusitis in Children | March 2007 | March 2010 |
| NCT00492024 | Completed | Phase 3 | BAY12-8039: 5 Days for Sinusitis vs Placebo | January 2005 | March 2008 |
| NCT00517946 | Completed | A Study To Investigate If MRI Scanning Is Effective At Seeing What Hayfever Drugs Do In Nasal Passage. | March 2007 | April 2007 | |
| NCT00534768 | Completed | N/A | Postoperative Treatment After Endoscopic Sinus Surgery | January 2003 | |
| NCT00543998 | Completed | Near Infrared Transillumination of the Paranasal Sinuses | May 2003 | June 2005 | |
| NCT05126407 | Completed | A Study of Olynth Saline/Ectomed Nasal Drops/Spray Based Upon Previous Usage | December 17, 2021 | January 20, 2022 | |
| NCT00588016 | Completed | Phase 1 | Concentration of Itraconazole Solution in Nasal Secretions | April 2007 | December 2013 |
| NCT00634608 | Completed | N/A | Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow | February 2008 | September 2009 |
| NCT00645762 | Completed | Phase 2 | Balloon REmodeling Antrostomy THErapy Study | September 2007 | June 2010 |
| NCT05049434 | Completed | N/A | Efficacy and Safety for Medicurtain® in Prevention of Adhesion After Endoscopic Sinus Surgery (Pivotal Study) | March 3, 2014 | March 31, 2015 |
| NCT04841343 | Completed | Triamcinolone Packing Following Endoscopic Sinus Surgery | January 29, 2021 | September 30, 2022 | |
| NCT00739921 | Completed | N/A | The Polymerase Chain Reaction (PCR) Analysis of Nasal Polyps for Fungal DNA | June 2006 | May 2015 |
| NCT00747747 | Completed | Phase 4 | Sinuclean's Treatment Of Sinusitis' Symptoms | November 2007 | February 2010 |
| NCT00791934 | Completed | Phase 3 | Clinical Study of Safety and Efficacy for the Relieva Stratus With Elution of Triamcinolone Acetonide | August 2008 | November 2011 |
| NCT04678856 | Completed | Phase 2 | Dupilumab in CRSsNP | December 2, 2020 | January 29, 2024 |
| NCT00896883 | Completed | N/A | Evaluation of the Middle Turbinate Implant for Affixing the Middle Turbinate to the Nasal Septum | April 2009 | May 2010 |
| NCT00934830 | Completed | Phase 3 | Antibiotics Versus Therapeutic Ultrasound for Sinusitis | January 2005 | October 2008 |
| NCT00944515 | Completed | N/A | Efficacy of Azithromycin Prophylaxis in Preventing Recurrent Acute Sinusitis in Children | August 2009 | December 2015 |
| NCT00970190 | Completed | Olfactory Dysfunction of Rhinosinusitis - Cyclic Adenosine Monophosphate (cAMP)/Calcium Signaling Study | August 2009 | April 2014 | |
| NCT01001039 | Completed | Validation of the Facial and Cephalic Pain Inventory | October 2009 | June 2012 | |
| NCT01033799 | Completed | N/A | Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers | October 2006 | August 2007 |
| NCT01050465 | Completed | N/A | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use | May 2009 | December 2010 |
| NCT01107379 | Completed | Optimization and Refinement of Technique in In-Office Sinus Dilation 2 | April 2010 | July 2012 | |
| NCT01115309 | Completed | N/A | XprESS Registry Study | April 2010 | December 2011 |
| NCT01118312 | Completed | Phase 4 | Study of Asthma and Nasal Steroids | September 2010 | June 2015 |
| NCT01129765 | Completed | Home Usability of a Nasal Lavage System in Children | July 2009 | August 2009 | |
| NCT03783702 | Completed | Phase 4 | Pain Control Following Sinus Surgery | April 4, 2019 | December 30, 2020 |
| NCT01156701 | Completed | Prophylactic Efficacy of Relenza Against Influenza A and B | July 2009 | May 2010 | |
| NCT01166945 | Completed | N/A | Short (5 Days) Versus Long (14 Days) Duration of Antimicrobial Therapy for Acute Bacterial Sinusitis in Children | November 2010 | February 2016 |
| NCT03535558 | Completed | Fluoroquinolone Associated Disability | May 17, 2018 | December 31, 2018 | |
| NCT01255566 | Completed | Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study | August 2009 | August 2012 | |
| NCT03390257 | Completed | N/A | Study to Evaluate the Safety and Initial Effectiveness of the Sinusway™ for Endoscopy of Sinuses in Conjunction With BSD | April 25, 2017 | May 2, 2019 |
| NCT01350193 | Completed | Phase 1/Phase 2 | Manuka Honey Irrigation After Sinus Surgery | June 2011 | April 2013 |
| NCT01420471 | Completed | Phase 4 | Medicated Punctured-Glove-Finger Spacer Study | September 2011 | June 2012 |
| NCT01442740 | Completed | N/A | 15-Degree Tilt, Head Up, Feet Down Body Position for Sinus Surgery Patients | October 2011 | May 2012 |
| NCT01485484 | Completed | Development and Validation of a NIRS-based Sinusitis Screening | July 28, 2011 | July 7, 2015 | |
| NCT01492868 | Completed | Sinusitis in Children and the Nasopharyngeal Microbiome | January 2012 | June 2017 | |
| NCT03229551 | Completed | Phase 2/Phase 3 | Xylitol for Chronic Sinusitis | March 1, 2018 | July 16, 2018 |
| NCT01612780 | Completed | N/A | Trans-Nasal Maxillary Multi-Sinus Balloon Dilation Study | April 2012 | October 2013 |
| NCT01623050 | Completed | Phase 1 | Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium | April 2012 | September 2014 |
| NCT01671098 | Completed | Sinonasal Gas Exchange Dynamics | August 2013 | August 2015 | |
| NCT01684540 | Completed | Application of Ectoin® Rhinitis Nasal Spray in Patients With Acute Rhinosinusitis | February 2012 | August 2012 | |
| NCT01685229 | Completed | Medical Therapy Versus Balloon Sinus Dilation for Patients With Chronic Rhinosinusitis | September 1, 2012 | August 1, 2015 | |
| NCT01717274 | Completed | N/A | Hot Saline Irrigation Study | November 2012 | April 2015 |
| NCT03011632 | Completed | Phase 4 | Response of the Airway in Sinusitis and Asthma | January 2017 | August 2019 |
| NCT01825408 | Completed | Phase 4 | Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis | February 2013 | June 2014 |
| NCT02933918 | Completed | N/A | Safety of Intranasal Irrigation Probiotics in Healthy Volunteers | May 17, 2018 | December 30, 2019 |
| NCT01907204 | Completed | Phase 2/Phase 3 | Evaluation of Inhaled Treatment in Sinusitis | July 2013 | January 2014 |
| NCT01919411 | Completed | Phase 4 | Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial | February 2013 | September 2018 |
| NCT02927834 | Completed | N/A | Oral Steroids in Chronic Rhinosinusitis Without Nasal Polyps | August 2015 | January 2019 |
| NCT02077322 | Completed | N/A | Rates of Middle Meatal Synechia Formation Following Functional Endoscopic Sinus Surgery | March 2014 | May 2017 |
| NCT02079792 | Completed | Phase 4 | The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device | June 2014 | August 2015 |
| NCT02110654 | Completed | Phase 4 | Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery | June 2014 | November 1, 2020 |
| NCT02191046 | Completed | N/A | Effect of Squeezable Bottle Nasal Irrigation Device in Children With Sinusitis | March 2013 | May 2014 |
| NCT02194062 | Completed | N/A | Comparison of Nasal Steroids After FESS in CRSwNP | January 2015 | August 2015 |
| NCT02221128 | Completed | PerClot to Control Bleeding in Endoscopic Sinus Surgery | July 2014 | September 2014 | |
| NCT02278484 | Completed | N/A | Sinus Balloon Dilation in Pediatric Patients | September 2014 | January 2016 |
| NCT02340000 | Completed | Phase 4 | Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate | November 18, 2014 | February 27, 2017 |
| NCT02924103 | Completed | N/A | Contamination Free Bacterial Swap | December 2016 | March 1, 2018 |
| NCT02855931 | Completed | N/A | Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps | April 2016 | December 31, 2017 |
| NCT02554383 | Completed | Phase 3 | Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit? | February 2016 | March 9, 2023 |
| NCT02502084 | Completed | N/A | Safety and Effectiveness Evaluation of the Sinusway Device for Endoscopy of the Nasal Cavity and Paranasal Sinuses | August 2015 | June 2017 |
| NCT02463279 | Completed | N/A | SinuSys Patency of Frontal Recess and Sphenoid Sinus Ostia Study | April 2015 | March 2016 |
| NCT00002149 | Completed | N/A | Acupuncture and Herbal Treatment of Chronic HIV Sinusitis | ||
| NCT06182982 | Not yet recruiting | N/A | Auriculotherapy for Intraoperative Blood Pressure Control | June 15, 2024 | July 30, 2024 |
| NCT06023550 | Not yet recruiting | Complicated Infections in Otorhinolaryngology | August 2024 | September 2028 | |
| NCT03729258 | Recruiting | Phase 3 | Efficacy and Safety of Modified Release Cefpodoxime Formulation in the Treatment of Acute Sinusitis. | May 15, 2019 | December 1, 2023 |
| NCT03256773 | Recruiting | High Resolution Micro OCT Imaging | April 15, 2016 | December 31, 2024 | |
| NCT02975310 | Recruiting | N/A | In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps | April 11, 2017 | December 2025 |
| NCT06089278 | Recruiting | Phase 2 | A Clinical Study of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps. | December 29, 2023 | May 2025 |
| NCT05924711 | Recruiting | "Association of Peri-implantitis and Maxillary Sinusitis: a Case-control Study". | June 6, 2023 | July 15, 2023 | |
| NCT05390255 | Recruiting | Phase 3 | Establishment of Precise Diagnosis and Treatment System for Refractory Chronic Rhinosinusitis | May 25, 2022 | December 31, 2024 |
| NCT04241016 | Recruiting | N/A | Endoscopic Sinus Surgery in Recurrent Acute Rhinosinusitis | May 1, 2020 | May 30, 2025 |
| NCT02454608 | Terminated | N/A | Trial of Verapamil in Chronic Rhinosinusitis | May 2015 | May 2017 |
| NCT02627794 | Terminated | Phase 3 | Rates of Middle Meatus Synechiae Formation Post Endoscopic Sinus Surgery | December 2015 | April 2016 |
| NCT02630472 | Terminated | Phase 1/Phase 2 | Topical Irrigation Therapy for CRS | October 2015 | May 4, 2017 |
| NCT03036735 | Terminated | N/A | Rates of Middle Meatus Synechiae Formation Post ESS | April 5, 2015 | December 2016 |
| NCT03102190 | Terminated | Phase 1 | Trial of Topical Verapamil in Chronic Rhinosinusitis With Nasal Polyps | June 5, 2017 | March 26, 2018 |
| NCT01315418 | Terminated | N/A | Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation | December 2006 | July 2007 |
| NCT03454607 | Terminated | N/A | Foot Controlled Robotic Endoscope Enabled Robot FESS | January 4, 2018 | November 30, 2018 |
| NCT00705237 | Terminated | Phase 4 | Study of the Use of LUMA Lightwire | March 2008 | February 2009 |
| NCT00493038 | Terminated | Phase 4 | Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis | February 2006 | January 2008 |
| NCT00423176 | Terminated | Phase 3 | The Study of Nasonex® Compared With Placebo for the Relief of Symptoms Associated With Acute Bacterial Sinusitis When Used With Antibiotics (Study P04824AM3) | December 2006 | June 2008 |
| NCT02931604 | Unknown status | N/A | Study Designed to Clinically Evaluate Sinus Wash Device Prototypes | January 2017 | January 2020 |
| NCT02367118 | Unknown status | Phase 3 | Prednisone in Chronic Rhinosinusitis Without Nasal Polyps | June 2015 | December 2016 |
| NCT02407275 | Unknown status | N/A | Rhinosinusites Chroniques | February 2015 | |
| NCT02413125 | Unknown status | N/A | Comparison of Nasal Saline Irrigation Bottle Contamination Between Two Solutions | February 2015 | June 2015 |
| NCT01564849 | Unknown status | The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract for Patients With Chronic Rhinosinusitis | April 2012 | February 2017 | |
| NCT03374124 | Unknown status | The Surgical Prognosis Based Diagnostic Strategy for Eosinophilic Chronic Rhinosinusitis | January 2016 | June 2018 | |
| NCT02799446 | Unknown status | Phase 3 | Effect of Reslizumab in Chronic Rhinosinusitis | June 2016 | July 2019 |
| NCT03943121 | Unknown status | N/A | The Effects of Steroid-eluting Stent Implant for the Treatment of Eosinophilic Chronic Rhinosinusitis With Nasal Polyps | October 8, 2018 | October 1, 2021 |
| NCT02506426 | Unknown status | N/A | Endoscopic Sinus Surgery for Refractory Chronic Sinusitis | July 2015 | July 2018 |
| NCT00803881 | Unknown status | Longitudinal Pathogen-colonization in Cystic Fibrosis Airways and Ability to Smell | December 2008 | December 2018 | |
| NCT01248325 | Unknown status | Phase 3 | A Study of Luffa Operculate Nasal Solution 5mg/mL Compared With Saline (NaCl 09%) for the Relief of Nasal Obstruction | January 2011 | July 2011 |
| NCT03584178 | Unknown status | N/A | The Long-Term Safety of Budesonide for Patients With Chronic Rhinosinusitis | September 5, 2018 | December 25, 2021 |
| NCT00545961 | Unknown status | Phase 4 | Middle Meatal Bacteriology During Acute Respiratory Infection in Children | November 2007 | December 2009 |
| NCT05301777 | Unknown status | Computed Tomography Anatomy of the Paranasal Sinuses and Anatomical Variants of Clinical Relevants in Egyptian Adults . | April 1, 2022 | June 1, 2023 | |
| NCT01906697 | Unknown status | Phase 3 | The Effect of RF Turbinoplasty in Polypoid Change of Middle Turbinates | May 2011 | October 2013 |
| NCT02071667 | Withdrawn | Association of Periostin Levels and Chronic Sinusitis | September 2014 | October 2016 | |
| NCT01155752 | Withdrawn | Phase 3 | Pulmozyme in Cystic Fibrosis With Sinusitis | July 2013 | June 2015 |
| NCT02900794 | Withdrawn | N/A | Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery | October 2016 | July 2018 |
| NCT00705354 | Withdrawn | N/A | Pilot Study To Evaluate A Pharmacologically Active Nasal Sponge Following Endoscopic Sinus Surgery | January 2009 | October 2010 |
| NCT00000752 | Withdrawn | Phase 2 | Preventing Frequent Sinus Infections in HIV-Infected Patients | February 1993 | |
| NCT01814618 | Withdrawn | Phase 2 | Trial of Directed High-dose Nasal Steroids on Residual Smell Loss in Sinus Patients After Sinus Surgery | March 2013 | November 2013 |
- Disase is a (Disease Ontology)
- DOID:1352
- Cross Reference ID (Disease Ontology)
- ICD10CM:J01
- Cross Reference ID (Disease Ontology)
- ICD9CM:461
- Cross Reference ID (Disease Ontology)
- NCI:C128411
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:195649005
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0149512
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0000246
- MeSH unique ID (MeSH (Medical Subject Headings))
- D012852