severe acute respiratory syndrome

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Information
Disease name
severe acute respiratory syndrome
Disease ID
DOID:2945
Description
"A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia." [url:http\://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=SARS]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04462367 Active, not recruiting Northeast COVID-19 and Pregnancy Study Group July 1, 2020 December 20, 2024
NCT04433949 Active, not recruiting Phase 3 Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 June 23, 2020 May 30, 2024
NCT04527432 Active, not recruiting N/A COVID-19 Health Professional Impact Study November 24, 2020 June 30, 2024
NCT00342524 Completed Collection of Convalescent SARS Plasma by Apheresis July 6, 2005 February 8, 2007
NCT03225807 Completed Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure March 2016 December 1, 2022
NCT03465085 Completed Phase 3 Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS February 18, 2016 January 30, 2018
NCT04315896 Completed Phase 3 Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection (HYDRA Trial) April 14, 2020 August 15, 2020
NCT04318015 Completed Phase 3 Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial) April 14, 2020 March 31, 2021
NCT04324463 Completed Phase 3 Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial April 21, 2020 December 30, 2022
NCT04328129 Completed N/A Household Transmission Investigation Study for COVID-19 in Tropical Regions March 23, 2020 September 30, 2021
NCT00150475 Completed N/A Contamination During Removal of Two Different Personal Protective Systems January 2005 May 2005
NCT00215826 Completed Phase 2 Study of Alferon® LDO (Low Dose Oral) in Normal Volunteers November 2004 April 2006
NCT04402060 Completed Phase 1/Phase 2 A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 May 28, 2020 February 13, 2021
NCT04402957 Completed Phase 2 LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19) October 14, 2020 June 2, 2022
NCT04425213 Completed Obesity and Mortality of Critically Ill Patients With COVID-19 May 12, 2020 May 26, 2020
NCT04425863 Completed Ivermectin, Aspirin, Dexamethasone and Enoxaparin as Treatment of Covid 19 May 1, 2020 August 30, 2020
NCT04444700 Completed Phase 3 A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 Pandemic July 4, 2020 October 14, 2021
NCT04449276 Completed Phase 1 A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19 June 18, 2020 December 21, 2021
NCT04490850 Completed N/A COVID-19 Seroprevalence Study in French Guiana July 15, 2020 September 24, 2021
NCT04515147 Completed Phase 2 A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19 September 21, 2020 February 21, 2022
NCT04542915 Completed COVID-19-Related Health and Practices Among Dental Hygienists September 29, 2020 August 31, 2021
NCT04581889 Completed Prevalence of Antibodies Against SARS-CoV-2 Virus That Causes COVID-19 in Tübingen Children July 2, 2020 July 31, 2022
NCT04602351 Completed Communication in ICU During COVID-19 March 22, 2021 May 1, 2021
NCT04636671 Completed Phase 3 Methylprednisolone vs. Dexamethasone in COVID-19 Pneumonia (MEDEAS RCT) April 14, 2021 May 4, 2022
NCT04674189 Completed Phase 3 A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany for COVID-19 December 23, 2020 June 8, 2022
NCT04745442 Completed Phase 2 Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19 April 27, 2020 January 15, 2021
NCT04839146 Completed Phase 1 Safety and Tolerability of COVID-19 Vaccine (ABNCoV2) March 11, 2021 February 25, 2022
NCT06287554 Completed Effect of Early Implementation of Prone Positioning March 4, 2020 April 20, 2022
NCT04357730 Completed Phase 2 Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection May 14, 2020 September 30, 2021
NCT04366934 Completed Study of the Pathogenesis of Olfactory Disorders in COVID-19 May 4, 2020 October 29, 2020
NCT04376684 Completed Phase 2 Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease May 28, 2020 August 16, 2021
NCT04395144 Completed N/A COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss May 15, 2020 March 15, 2021
NCT04386070 Not yet recruiting Phase 3 Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19 October 1, 2021 May 14, 2026
NCT04470544 Recruiting Phase 2 Camostat Mesilate Treating Patients With Hospitalized Patients With COVID-19 July 28, 2020 September 15, 2022
NCT04381936 Recruiting Phase 3 Randomised Evaluation of COVID-19 Therapy March 19, 2020 June 30, 2036
NCT04320511 Terminated Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2 June 24, 2020 May 14, 2021
NCT04335786 Terminated Phase 4 Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease April 17, 2020 May 25, 2021
NCT04860258 Terminated Phase 3 COVID-19: A Study to Evaluate Safety, Reactogenicity and Immunogenicity of the SARS-CoV-2 mRNA Vaccine CVnCoV in Adults With Co-morbidities April 22, 2021 September 21, 2021
NCT04602507 Terminated Phase 2 Ivermectin in Adults With Severe COVID-19. December 10, 2020 December 9, 2021
NCT00578825 Unknown status N/A A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory Syndrome
NCT04627623 Unknown status Prevalence and Risk Factors of COVID-19 in the Upper Silesian Agglomeration June 22, 2020 April 22, 2021
NCT04480333 Unknown status Phase 1 Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831 September 15, 2020 March 31, 2021
NCT04412746 Unknown status Covid-19 and Diabetes in West of Algeria April 1, 2020 June 30, 2020
NCT04381819 Unknown status Norwegian SARS-CoV-2 Study - Virological, Clinical and Immunological Characterisation of COVID-19 March 2, 2020 December 31, 2023
NCT00172263 Withdrawn N/A The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and Monocytes
NCT00073086 Withdrawn Evaluation and Treatment of Severe Acute Respiratory Syndrome (SARS) November 5, 2003 December 27, 2010
NCT04838847 Withdrawn Phase 3 A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19 October 1, 2021 September 2022
NCT04411602 Withdrawn Phase 1 Intermediate IND Severe Illness COVID-19 CP April 7, 2020 April 7, 2021
Disase is a (Disease Ontology)
DOID:0080599
Cross Reference ID (Disease Ontology)
GARD:9237
Cross Reference ID (Disease Ontology)
ICD10CM:J12.81
Cross Reference ID (Disease Ontology)
ICD9CM:079.82
Cross Reference ID (Disease Ontology)
MESH:D045169
Cross Reference ID (Disease Ontology)
NCI:C85064
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:398447004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C1175175
Exact Synonym (Disease Ontology)
SARS
Exact Synonym (Disease Ontology)
SARS-CoV infection
MeSH unique ID (MeSH (Medical Subject Headings))
D045169