leprosy
Information
- Disease name
- leprosy
- Disease ID
- DOID:1024
- Description
- "A primary bacterial infectious disease that results_in infection located_in superficial peripheral nerves, located_in skin, located_in mucous membranes of the upper respiratory tract, located_in anterior chamber of the eyes, or located_in testes, has_material_basis_in Mycobacterium leprae, which is transmitted_by aerosol spread from infected nasal secretions to exposed nasal and oral mucosa. The infection has_symptom skin lesions, has_symptom sensory loss, has_symptom motor loss and has_symptom eye damage." [url:http\://en.wikipedia.org/wiki/Leprosy]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03662022 | Completed | Phase 3 | Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar | January 2, 2019 | January 31, 2023 |
| NCT00138437 | Completed | Molecular and Immunological Tools for Detection of Strain Diversity, Drug Resistance and Immunological Responses | April 2006 | April 2013 | |
| NCT00315809 | Completed | Molecular Epidemiology of Leprosy - Philippines | April 2006 | December 2010 | |
| NCT00128193 | Completed | Phase 2 | Leprosy Skin Test Antigens Trial | April 2002 | September 2009 |
| NCT00669643 | Completed | Phase 4 | Uniform Multidrug Therapy Regimen for Leprosy Patients | February 2007 | December 31, 2016 |
| NCT03526718 | Completed | Improved Understanding of Ongoing Transmission of Leprosy in the Hyperendemic Comoros (ComLep) | April 1, 2017 | December 31, 2020 | |
| NCT03683745 | Completed | Integrated Mapping of Skin-presenting Neglected Tropical Diseases in Liberia | June 14, 2018 | December 30, 2018 | |
| NCT00860717 | Completed | N/A | The Use of Low Level Laser Therapy for Wound Healing in Leprosy Patients | November 2006 | April 2008 |
| NCT00919451 | Completed | Phase 2 | Ciclosporin in the Management of Steroid Resistant Type 1 Reactions in Leprosy | August 2010 | July 2013 |
| NCT00919542 | Completed | Phase 2 | Ciclosporin in the Management of New Erythema Nodosum Leprosum | July 2010 | July 2013 |
| NCT00919776 | Completed | Phase 2 | Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum | August 2010 | July 2013 |
| NCT00919815 | Completed | Phase 2/Phase 3 | Ciclosporin in the Management of New Type 1 Reactions in Leprosy | August 2010 | July 2013 |
| NCT01006759 | Completed | Phase 1 | Prevention of Disability: Proposal for a Guidance Manual for Leprosy Patients | January 2007 | August 2009 |
| NCT01165840 | Completed | Phase 4 | Effect of Weight and/or Obesity on Dapsone Drug Concentrations | July 2010 | May 2012 |
| NCT05406479 | Completed | Phase 2 | Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2) | July 14, 2022 | January 26, 2023 |
| NCT01920750 | Completed | Phase 1 | Leprosy Skin Test Antigens Phase 1 | January 1989 | February 1999 |
| NCT02484469 | Completed | N/A | Impact of the Virtual Human Project on Team-based Learning: A Randomized-controlled Trial | July 2014 | March 2015 |
| NCT05091216 | Completed | N/A | The Effects of Traditional Chinese Medicine Mouthwash Solutions on the Oral Health of Leprosy Patients | October 1, 2021 | September 6, 2022 |
| NCT05047809 | Completed | N/A | The Effect of "Jinchuang Ointment" (JCO) on the Treatment of Wounds in Patients With Hansen's Disease. | August 7, 2021 | May 5, 2022 |
| NCT03302897 | Completed | Phase 1 | Phase 1 LEP-F1 + GLA-SE Vaccine Trial in Healthy Adult Volunteers | October 2, 2017 | March 5, 2019 |
| NCT00852345 | No longer available | Treatment Protocol for Clofazamine in the Long Term Treatment of Leprosy | |||
| NCT03947437 | Not yet recruiting | Phase 1/Phase 2 | Phase 1b/2a Trial to Evaluate LEP-F1 + GLA-SE in Healthy Adults and Leprosy Patients | February 2024 | April 2025 |
| NCT06416033 | Recruiting | Serum Irisin Level In Leprosy Patients | January 1, 2024 | July 15, 2024 | |
| NCT03807362 | Recruiting | Phase 2 | CC-11050 Trial in Nepalese Patients With Erythema Nodosum Leprosum | January 7, 2018 | December 31, 2024 |
| NCT05243654 | Recruiting | Phase 2 | Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy | October 1, 2022 | February 28, 2026 |
| NCT05597280 | Recruiting | Phase 3 | Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy | March 22, 2023 | December 31, 2026 |
| NCT06222372 | Recruiting | N/A | Novel Interventions and Diagnostic Tests for Leprosy | March 4, 2020 | November 2025 |
| NCT01751503 | Terminated | N/A | Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer | March 2013 | December 2019 |
| NCT03084614 | Terminated | CD8 Reactivity to Microorganisms in Blood and Breast Milk | March 28, 2017 | November 8, 2019 | |
| NCT00406861 | Unknown status | N/A | Montelukast in ENL Reaction | December 2006 | June 2009 |
| NCT03324035 | Unknown status | Phase 3 | Treatment of Neuropathic Pain in Leprosy | March 1, 2017 | August 1, 2022 |
| NCT02550080 | Unknown status | Phase 4 | Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome | July 2015 | May 2019 |
- Disase is a (Disease Ontology)
- DOID:0050338
- Cross Reference ID (Disease Ontology)
- EFO:0001054
- Cross Reference ID (Disease Ontology)
- GARD:6886
- Cross Reference ID (Disease Ontology)
- ICD10CM:A30
- Cross Reference ID (Disease Ontology)
- ICD9CM:030
- Cross Reference ID (Disease Ontology)
- MESH:D007918
- Cross Reference ID (Disease Ontology)
- MIM:607572
- Cross Reference ID (Disease Ontology)
- MIM:609888
- Cross Reference ID (Disease Ontology)
- MIM:613407
- Cross Reference ID (Disease Ontology)
- NCI:C84824
- Cross Reference ID (Disease Ontology)
- ORDO:548
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154298007
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0023343
- OrphaNumber from OrphaNet (Orphanet)
- 548
- MeSH unique ID (MeSH (Medical Subject Headings))
- D007918