Unipolar Depression
Information
- Disease name
- Unipolar Depression
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03191058 | Active, not recruiting | N/A | Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression | June 26, 2018 | November 7, 2024 |
| NCT00125957 | Completed | Phase 3 | The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression | August 2005 | December 2011 |
| NCT00158990 | Completed | Phase 3 | Triiodothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression. | October 2002 | July 2007 |
| NCT00178074 | Completed | Phase 4 | The Effects of Sleep Deprivation on Antidepressant Response | February 1999 | April 2003 |
| NCT00178100 | Completed | Phase 4 | Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression | March 1999 | August 2005 |
| NCT00179244 | Completed | Phase 3 | Risperidone vs. Bupropion ER Augmentation of SSRIs in Treatment-Resistant Depression | July 2004 | April 2005 |
| NCT00186784 | Completed | Early Phase 1 | Transcranial Magnetic Treatment (TMS) in Unipolar Depression | December 2000 | July 2011 |
| NCT00226356 | Completed | Phase 4 | Natural Supplements for Unipolar Depression | December 2004 | September 17, 2008 |
| NCT00265291 | Completed | Phase 2 | Antidepressant Treatment of Mexican-Americans: UCLA Pharmacogenetics and Pharmacogenomics Research Group | November 1999 | October 2008 |
| NCT00319540 | Completed | Phase 2 | RCT of Psychoeducational Program of Depression | March 2001 | March 2002 |
| NCT03685942 | Completed | N/A | Efficacy of Light Therapy Device LUMINETTE® in Major Depressive Disorder | January 16, 2019 | September 8, 2023 |
| NCT01544205 | Completed | N/A | Neurofeedback as a Treatment Tool for Depression | March 2012 | September 2014 |
| NCT01562184 | Completed | Phase 2/Phase 3 | Investigating tDCS as a Treatment for Unipolar and Bipolar Depression | June 2012 | October 2015 |
| NCT01644747 | Completed | Phase 2 | tDCS as an add-on Treatment for Resistant Major Depression in Uni- or Bipolar Patients | July 19, 2012 | March 1, 2022 |
| NCT01880957 | Completed | N/A | PET and MRI Brain Imaging of Bipolar Disorder | November 8, 2011 | June 23, 2017 |
| NCT01881763 | Completed | Phase 4 | Ketamine as an Augmentation Strategy for Electroconvulsive Therapy (ECT) in Depression | June 2010 | July 2017 |
| NCT02104232 | Completed | N/A | Thinking Healthy Program - Peer Delivered, India (THPP-I) | October 2014 | May 2017 |
| NCT02111915 | Completed | N/A | Thinking Healthy Program - Peer Delivered (Pakistan) | October 2014 | February 2017 |
| NCT02401139 | Completed | Phase 1 | Ketamine Trial for the Treatment of Depression | March 2015 | September 2015 |
| NCT02407704 | Completed | Phase 4 | A Multi-level Life-span Characterization of Adult-depression and Effects of Medication and Exercise | March 2015 | December 2016 |
| NCT02530164 | Completed | N/A | Transcranial Direct Current Stimulation (tDCS) As Treatment for Major Depression | September 2015 | February 2021 |
| NCT02750631 | Completed | N/A | Out-patient Wake Therapy, Light Therapy and Sleep Phase Advance for Depression | April 2014 | July 2017 |
| NCT02771535 | Completed | N/A | Long-term Efficacy of Metacognitive Training for Depression (D-MCT) | March 2016 | May 2017 |
| NCT02822443 | Completed | Phase 2 | Improve: Integrating Emotion Focused Components Into Psychological Therapy | April 2015 | August 2019 |
| NCT03033420 | Completed | N/A | Reducing the Rate and Duration of Re-ADMISsions Among Patients With Unipolar Disorder and Bipolar Disorder Using Smartphone-based Monitoring and Treatment - The RADMIS Trials | May 15, 2017 | May 1, 2021 |
| NCT03113968 | Completed | Phase 2/Phase 3 | ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD) | April 7, 2017 | November 17, 2022 |
| NCT03156504 | Completed | Phase 4 | The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression. | June 1, 2017 | March 12, 2020 |
| NCT03256162 | Completed | Phase 1 | Ketamine as an Adjunctive Therapy for Major Depression | September 7, 2017 | September 21, 2018 |
| NCT03268434 | Completed | N/A | Evaluation of Metacognitive Training for Depression (D-MCT) in Outpatient Care | October 10, 2017 | September 24, 2019 |
| NCT03315897 | Completed | Phase 2 | Effects of Erythropoietin on Cognition and Neural Activity in Mood Disorders | July 5, 2017 | October 1, 2022 |
| NCT03339596 | Completed | Phase 2 | Effects of Erythropoietin for Cognitive Side-effects of ECT | June 26, 2017 | February 10, 2023 |
| NCT00001545 | Completed | Phase 2 | Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders | May 1996 | July 2006 |
| NCT04420793 | Completed | Voice Changes During ECT | November 7, 2019 | February 17, 2021 | |
| NCT04701866 | Completed | N/A | Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in Depression | January 11, 2021 | August 24, 2022 |
| NCT04781127 | Completed | Phase 1 | Home-administered tDCS for Treatment of Depression | February 10, 2021 | August 10, 2022 |
| NCT04889976 | Completed | N/A | Portable Transcranial Electrical Stimulation and Internet-Based Behavioral Therapy for Major Depression Study | May 22, 2021 | October 21, 2022 |
| NCT05388539 | Completed | N/A | TBS Treatment for Treatment-Resistant Depression | June 6, 2022 | April 1, 2024 |
| NCT00517387 | Completed | Phase 3 | The Effects of Quetiapine XR on Cognition, Mood and Anxiety Symptoms in SSRI-Resistant Unipolar Depression | September 2007 | September 2010 |
| NCT00714090 | Completed | Phase 3 | Repetitive Transcranial Magnetic Stimulation and Venlafaxine in Depression | May 2008 | July 2013 |
| NCT00901407 | Completed | N/A | Lamotrigine Augmentation in Resistant Depression | December 2003 | April 2007 |
| NCT00914680 | Completed | Phase 3 | Berlin Magnetic Seizure Therapy Depression Trial 01 | June 2009 | May 2013 |
| NCT00922064 | Completed | Phase 4 | Effects of Electroconvulsive Therapy (ECT) on Serotonin-1A Receptor Binding | June 2009 | September 2011 |
| NCT00964054 | Completed | Phase 1 | Depression Outcomes Study of Exercise | September 2012 | February 2013 |
| NCT01049347 | Completed | Phase 3 | Amitriptyline and Paroxetine Treatment of Major Depression | October 1997 | May 2000 |
| NCT01132872 | Completed | PET Whole Body Distribution Studies Using [11C]CUMI | April 30, 2010 | April 12, 2012 | |
| NCT01360307 | Completed | Validation of the Spanish Version of the Clinically Useful Depression Outcome Scale (CUDOS) Scale | June 2011 | November 2011 | |
| NCT01447602 | Completed | Phase 3 | A Clinical Trial of IPT-A to Prevent Suicide in Depressed Adolescents With Suicidal Behavior | September 2011 | June 2014 |
| NCT06126198 | Enrolling by invitation | N/A | rTMS Feasibility Study on Adolescent Depression Stimulation | January 1, 2022 | December 31, 2023 |
| NCT06363981 | Not yet recruiting | N/A | Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression | May 2024 | April 2027 |
| NCT06371352 | Not yet recruiting | N/A | Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression | May 2024 | May 2027 |
| NCT04059952 | Recruiting | Mechanism of Action of Electroconvulsive Therapy | June 28, 2019 | December 1, 2024 | |
| NCT04370002 | Recruiting | Sensor-based Characterization of Depression | January 28, 2020 | November 30, 2024 | |
| NCT03711019 | Recruiting | N/A | Efficacy of Convulsive Therapies During Continuation | October 22, 2018 | September 2024 |
| NCT03895658 | Recruiting | Phase 1 | Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST) | June 23, 2024 | December 31, 2025 |
| NCT05570110 | Recruiting | Phase 1/Phase 2 | Enoxolone in Major Depression - Biomarker-outcome Relationship | September 23, 2022 | March 2025 |
| NCT04939649 | Recruiting | Phase 3 | Ketamine as an Adjunctive Therapy for Major Depression (2) | September 13, 2021 | December 1, 2024 |
| NCT05801562 | Recruiting | Development of a Software Tool, Using Artificial Intelligence, That Integrates Clinical, Biological, Genetic and Imaging Data to Predict Diagnosis and Outcome of Depressed Patients in Order to Enhance Prognosis and Limiting Healthcare Costs. | July 14, 2020 | February 14, 2025 | |
| NCT05894980 | Recruiting | N/A | How to Reduce Suicidal Thoughts and Impulsivity in Depression | September 1, 2023 | February 2026 |
| NCT01557192 | Suspended | Phase 1 | Low Field Magnetic Stimulation (LFMS) in Mood Disorders: 6 Treatments | May 2010 | May 2020 |
| NCT00369915 | Terminated | Phase 2 | The Antidepressant Efficacy of the Anticholinergic Scopolamine | August 2006 | January 2013 |
| NCT00617162 | Terminated | N/A | Deep Brain Stimulation for Major Depressive Disorder | March 2008 | June 2015 |
| NCT02710279 | Terminated | N/A | Response to Social Rejection in Suicidal Behavior | February 19, 2016 | February 15, 2018 |
| NCT01219686 | Terminated | Phase 2/Phase 3 | EScitalopram PIndolol ONset of Action | October 2010 | June 2013 |
| NCT04712968 | Terminated | N/A | Efficacy of Daylight as Adjunctive Treatment in Patients With Depression | September 1, 2021 | June 1, 2022 |
| NCT00055575 | Terminated | Phase 2 | Cholinergic Modulation of Condition and Emotion in Mood Disorders: Functional Neuroimaging Studies | February 27, 2003 | February 2, 2015 |
| NCT01574742 | Unknown status | Phase 1 | Open Study Assessing the Feasibility of Minocycline in Patients With Unipolar Depression | June 2012 | June 2014 |
| NCT03227133 | Unknown status | N/A | Oral Fluency and the Response to Antidepressant Therapy in the Elderly With a Unipolar Depressive Episode | December 23, 2016 | June 23, 2019 |
| NCT01694030 | Unknown status | Phase 1 | Effects of Repeated Attachment Security Priming on Depressed Mood: a Clinical Study | November 2012 | December 2014 |
| NCT04717921 | Unknown status | Assesment of Retinal Nerve Fiber Layer in First Episode Depressive Patients Using Selective Serotonin Reuptake Inhibitor | September 1, 2020 | September 1, 2021 | |
| NCT03358056 | Unknown status | N/A | Effects of Mindfulness Based Cognitive Therapy on Emotional Processing | September 1, 2017 | April 1, 2018 |
| NCT01894932 | Unknown status | N/A | MBCGT and Psycho-physiological Stress Regulation Group for Depression and Psycho-physiological Stress Patient | April 2011 | August 2016 |
| NCT01012856 | Unknown status | Phase 2 | Randomized Clinical Trial of an Exposure-based Cognitive Therapy for Depression | January 2010 | March 2014 |
| NCT01313403 | Withdrawn | N/A | Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive Disorder | February 10, 2011 | April 25, 2012 |