tetanus
Information
- Disease name
- tetanus
- Disease ID
- DOID:11338
- Description
- "A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli." [url:http\://en.wikipedia.org/wiki/Tetanus]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06123663 | Active, not recruiting | Phase 1 | A Study to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over | December 20, 2023 | July 2024 |
| NCT05480462 | Active, not recruiting | Phase 3 | Immunogenicity and Safety of Vaccine Against Tetanus and Diphtheria. | December 12, 2022 | June 2024 |
| NCT05091619 | Active, not recruiting | Phase 3 | A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed | October 22, 2021 | September 22, 2027 |
| NCT00136604 | Completed | Phase 3 | Response to GSK Biologicals' Tritanrix-HepB/Hib-MenAC Vacc (4th Dose) at 15-24m & Mencevax ACWY at 24-30m | January 22, 2006 | April 23, 2006 |
| NCT00138268 | Completed | Pilot Study Freeze and Transport Immune Cells | February 2005 | ||
| NCT00146835 | Completed | Post-marketing Safety Study of GSK Biological's Pediarix™ Vaccine | April 2003 | June 2006 | |
| NCT00148941 | Completed | Phase 3 | Immune Response and Safety Comparison of 3 Lots of GSK Biologicals' DTaP-IPV Candidate Vaccine to DTaP + IPV Vaccines | January 6, 2005 | December 4, 2006 |
| NCT00158808 | Completed | Phase 2 | Immune Memory Foll Pry Vaccination With DTPw-HBV/Hib Vaccine Formulation; Immuno & Reacto of Booster Dose at 15-18 Mths | January 2005 | April 2005 |
| NCT00168545 | Completed | Phase 4 | Immunology of Non-specific Effects of Vaccine | January 2006 | January 2007 |
| NCT00169442 | Completed | Phase 3 | Immune Memory of DTPw-HBV/Hib Vaccine Following Primary Vaccination, Immuno & Reacto of a Booster Dose Given in Infants | February 10, 2005 | March 10, 2006 |
| NCT00197275 | Completed | Phase 3 | Lot-to-lot Consistency of Tritanrix™-HepB/Hib-MenAC & Its Non-inferiority vs Tritanrix™-HepB/Hiberix™ in Infants | February 2006 | November 2006 |
| NCT00228917 | Completed | Phase 3 | Safety Study of Tritanrix-HepB/Hib-MenAC, Tritanrix-HepB/Hiberix, and Mencevax ACWY Vaccines in Children | June 16, 2005 | January 20, 2006 |
| NCT00254917 | Completed | Phase 4 | Assessment of the Immunogenicity and Safety of PENTAXIM™ in Philippines | October 2003 | February 2006 |
| NCT00254969 | Completed | Phase 3 | Immunogenicity and Safety of Pentaxim in South African Infants | October 2005 | January 2010 |
| NCT00255021 | Completed | Phase 4 | Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand | December 2005 | January 2009 |
| NCT00258895 | Completed | Phase 3 | Safety and Immunogenicity of DAPTACEL® as 5th Dose in Children 4 to 6 Years Old After 4 Doses of Pentacel™ or DAPTACEL® | March 2005 | April 2007 |
| NCT00258908 | Completed | Phase 3 | Immunogenicity and Safety of ADACEL™ as Fifth Dose in Taiwan | November 2005 | August 2006 |
| NCT00259337 | Completed | Phase 3 | Immunogenicity and Safety of Pentaxim™ in an Indian Population | February 2006 | December 2008 |
| NCT00263679 | Completed | Phase 3 | Assessment of GSK Biologicals' Tdap Candidate Vaccine Administered as a Booster (6th Dose) in Terms of Immunogenicity and Safety to Children and Adolescents Previously Vaccinated With Five Doses of an Acellular Pertussis-containing Vaccine. | November 2003 | October 2004 |
| NCT00263692 | Completed | Phase 2 | Comparison of GSK Biologicals' DTaP-IPV Candidate Vaccine to DTaP and IPV Separately Administered Vaccines in Terms of Immune Response and Safety | November 2002 | September 2004 |
| NCT00282295 | Completed | Phase 4 | US-licensed Combined Vaccine Against Tetanus & Diphtheria, Given With US-licensed Vaccine Against Meningococcal Disease | January 25, 2006 | August 8, 2006 |
| NCT00287092 | Completed | Phase 3 | Comparison of Safety and Immunogenicity of Pediacel™ and Infanrix™ IPV+Hib (Penta) Given in a 3 Dose Schedule in Infants | February 2006 | September 2008 |
| NCT00290303 | Completed | Phase 3 | Assess if Immune Response of GSK Biologicals' Tritanrix™-HepB/Hib-MenAC Given Without or With Hepatitis B Vaccine at Birth is at Least as Good as Tritanrix™-HepB/Hiberix™ Without Hepatitis B Vaccine at Birth, When Given to Healthy Infants | May 2004 | March 2005 |
| NCT00290342 | Completed | Phase 3 | Evaluation of the Immunogenicity, Safety and Reactogenicity of the Combined DTPa-IPV Vaccine in Healthy Infants | January 1, 2006 | January 23, 2007 |
| NCT00291967 | Completed | Phase 2 | Assess Immune Response Following Primary Vaccination With Tritanrix™-HepB Vaccine Mixed With 3 Formulations of Hib-MenAC Vaccine to Infants | November 2002 | |
| NCT00297856 | Completed | Post-marketing Safety Study of GSK Biologicals' Boostrix® Vaccine | March 2006 | December 2006 | |
| NCT00303316 | Completed | Phase 3 | Immunogenicity Study of Antibody Persistence and Booster Effect of PENTAXIM™ at 18 Months in Healthy Argentinean Infants | February 2006 | September 2007 |
| NCT00304265 | Completed | Phase 4 | Post-marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis Vaccine | March 2006 | October 2007 |
| NCT00307567 | Completed | Phase 2 | Multicentre Booster & Immune Memory Study of a Booster Dose of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine or a Single Dose of 23-valent Plain Polysaccharide Vaccine in Healthy Children Aged 11-18 Mths, Previously Vaccinated in Study 103488 | November 2005 | March 2006 |
| NCT00313911 | Completed | Phase 3 | Safety of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared to Tritanrix-HepB/Hib™ and OPV Given at Age 2, 4, and 6 Months. | July 2006 | February 2008 |
| NCT00316147 | Completed | Phase 3 | Immunogenicity & Safety of GSK's Combined DTPa-HBV-IPV/Hib Vaccine in Indian Infants at 2 Diff Vaccination Schedules | December 2005 | August 2006 |
| NCT00317135 | Completed | Phase 3 | Safety Study of a Vaccine Against Meningitis in Infants ( 2,4 & 6 Months Age) After a Birth Dose of Hepatitis B. | December 11, 2003 | October 23, 2004 |
| NCT00317161 | Completed | Phase 3 | Immunogenicity & Safety Study of a Vaccine Against Meningitis in Infants (2,4,6 Months) After a Hepatitis B Birth Dose. | August 2004 | April 2005 |
| NCT00317174 | Completed | Phase 2 | A Study to Assess Antibody Persistence, Boostability & Safety in Previously Primed Subjects. | July 2003 | April 2004 |
| NCT00317187 | Completed | Phase 3 | Safety Study of a Vaccine Against Meningitis in Infants (2,4 & 6 Months Age) After a Birth Dose of Hepatitis B. | June 8, 2004 | January 16, 2005 |
| NCT00319553 | Completed | Phase 4 | Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX® | May 2006 | December 2008 |
| NCT00319852 | Completed | Phase 3 | Immunogenicity and Safety of Tetraxim Versus Local DTP + IPV | April 2006 | July 2008 |
| NCT00320463 | Completed | Phase 3 | Compare Immunogenicity & Safety of 2 Formulations of GSK Biologicals' DTPa-HBV-IPV/Hib Vaccine Given in Healthy Infants | April 2006 | January 2007 |
| NCT00325130 | Completed | Phase 3 | Concomitant Use of Gardasil (V501) (Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diphtheria, Tetanus, Pertussis Vaccine and Meningococcal Conjugate Vaccine in Adolescents (V501-025) | April 2006 | April 2007 |
| NCT00325143 | Completed | Phase 3 | Safety of DTPa-IPV/Hib & DTPa-HBV-IPV/Hib, Followed by DTPa-IPV/Hib Vaccine in Infants Who Received Hepatitis B Vaccine | December 1, 2003 | February 1, 2007 |
| NCT00325156 | Completed | Phase 4 | Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy Infants | November 2, 2004 | August 23, 2007 |
| NCT00332566 | Completed | Phase 3 | Assess Immunogenicity, Reactogenicity, Safety of a Booster of GSK Biologicals DTPw-HBV/Hib Kft Compared to DTPw-HBV/Hib | June 2006 | October 2006 |
| NCT00337428 | Completed | Phase 3 | Concomitant Use of Gardasil (V501, Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diptheria, Tetanus, Pertussis and Poliomyelitis Vaccine in Adolescents (V501-024)(COMPLETED) | May 2006 | May 2007 |
| NCT00343421 | Completed | Phase 3 | Study to Compare Pediacel® to Infanrix®-IPV+Hib When Both Are Co-Administered With Prevenar® in Infants and Toddlers | July 2006 | June 2009 |
| NCT00343889 | Completed | Phase 3 | Comparison of DTaP-HB-PRP~T Combined Vaccine to Tritanrix-HepB/Hib™, Both Given Concomitantly With Oral Polio Vaccine | August 2006 | April 2008 |
| NCT00346073 | Completed | Phase 3 | Safety and Immunogenicity of GSK's Tdap Vaccine (Boostrix) in Adults Aged 19 to 64 Years | July 13, 2006 | March 7, 2007 |
| NCT00347958 | Completed | Phase 4 | Descriptive, Open-label, Multicenter Study of the Safety of Redosing With ADACEL® Vaccine | August 2006 | October 2008 |
| NCT00348881 | Completed | Phase 3 | Study Comparing a DTaP-HB-PRP~T Combined Vaccine With Tritanrix HepB/Hib™, Concomitantly With OPV in Healthy Infants | June 2006 | June 2008 |
| NCT00352963 | Completed | Phase 3 | Immunogenicity & Safety Study of Combined/Separate Vaccine(s) Against Common Diseases in Infants (2,4,6 Months of Age). | September 30, 2003 | July 16, 2004 |
| NCT00355121 | Completed | Phase 2 | Study of Menactra® in Children Aged 4 to 6 Years When Administered Concomitantly With a Fifth Dose of DAPTACEL® | October 2006 | July 2009 |
| NCT00362427 | Completed | Phase 2 | Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar® | August 2006 | March 2009 |
| NCT00376779 | Completed | Phase 2 | Immunogenicity and Safety of a DTPa-HBV-IPV/Hib Vaccine Given at 2, 3 and 4 Months of Age | October 2006 | May 2007 |
| NCT00379977 | Completed | Phase 3 | Study to Assess the Safety & Reactogenicity of GSK Biologicals' DTPa/Hib Vaccine When Given at 3, 4 and 5 Months of Age | September 2006 | December 2006 |
| NCT00385255 | Completed | Phase 3 | Immunogenicity, Safety of GSKs Tdap Vaccine Boostrix When Coadministered With GSKs Influenza Vaccine Fluarix in Adults | October 23, 2006 | February 28, 2007 |
| NCT00404651 | Completed | Phase 3 | Lot Consistency Study of DTaP-IPV-HB-PRP~T Vaccine Administered at 2-4-6 Months of Age in Healthy Infants | November 2006 | July 2008 |
| NCT00406562 | Completed | Phase 3 | Study to Assess the Safety & Reactogenicity of GSK Biologicals' dTpa Vaccine (Boostrix) When Given at 6-8 Years of Age. | January 2007 | February 2007 |
| NCT00412854 | Completed | Phase 3 | Study to Assess Safety & Immunogenicity of GSK Biologicals' DTPa/Hib Vaccine vs Separate Administration of DTPa and Hib. | January 3, 2007 | June 25, 2007 |
| NCT00432042 | Completed | Phase 3 | Immunogenicity and Safety Study of Proquad® and Infanrix® Hexa When Administered Concomitantly (V221-035) | January 12, 2007 | March 27, 2008 |
| NCT00447525 | Completed | Phase 3 | REVAXIS® Versus DT Polio® as a Second Booster in 6 Year-old Children | February 2007 | January 2008 |
| NCT00452686 | Completed | Phase 3 | Study to Assess Safety & Immunogenicity of GSK Biologicals' Boostrix (dTpa) Vaccine vs. Chinese DT Vaccine | March 2007 | May 2007 |
| NCT00453570 | Completed | Phase 3 | Immunogenicity and Safety of Pentaxim as 3 Doses Primary Vaccination Followed by a Booster Dose at 18 Months | March 2007 | January 2009 |
| NCT00457249 | Completed | Phase 4 | A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older | March 2007 | November 2008 |
| NCT00463437 | Completed | Phase 3 | Pneumococcal Vaccine Booster Study in Healthy Children 11-18 Months Old Previously Primed With the Same Vaccines | April 25, 2007 | June 14, 2008 |
| NCT00467519 | Completed | Phase 3 | Safety and Immunogenicity of Tdap Vaccine Compared to DTaP Vaccine in Children 4 to 6 Years of Age | April 2007 | December 2009 |
| NCT00473668 | Completed | Phase 3 | Non-inferiority of GSK Biologicals' DTPw-HBV/Hib Compared to Two Formulations of GSK Biologicals' DTPw-HBV/Hib | June 1, 2007 | January 30, 2008 |
| NCT00489970 | Completed | Phase 3 | Persistence Study of GSK Biologicals' Tdap Vaccine 1, 3, 5 and 9 Years Following Administration as an Initial Single Dose in Healthy Young Adults and to Evaluate the Immunogenicity and Safety of Boostrix as a Second Dose of Tdap, When Administered at Year 9 | June 1, 2007 | March 1, 2016 |
| NCT00514059 | Completed | Phase 4 | Immunogenicity and Safety Study of a Booster Dose (5th) of Diphteria-Tetanus-Pertussis-Polio Vaccine | April 2007 | June 2007 |
| NCT00514709 | Completed | Phase 3 | Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB PRP~T Combined Vaccine in Filipino Infants | September 2007 | April 2009 |
| NCT00518180 | Completed | Phase 3 | A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Conjugate Vaccine In Adolescents | July 2007 | October 2008 |
| NCT00534833 | Completed | Phase 3 | Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB-PRP~T Combined Vaccine or Tritanrix-HepB/Hib™ | September 2007 | March 2009 |
| NCT00548171 | Completed | Phase 4 | Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination in Study NCT01267058 | November 5, 2007 | April 30, 2008 |
| NCT00601835 | Completed | Phase 4 | Canadian Manufactured Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine Compared With U.S. Manufactured Td | May 2004 | July 2005 |
| NCT00610168 | Completed | Phase 4 | Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination. | January 1, 2008 | April 30, 2008 |
| NCT00611559 | Completed | Phase 4 | Study of a New Formulation of DTPa-HBV-IPV/Hib Vaccine Administered as a Booster Dose to 18-23 Months Old Children | February 14, 2008 | June 25, 2008 |
| NCT00617812 | Completed | Phase 4 | Safety and Immunogenicity Study of a Liquid Pentavalent Combination Vaccine | March 2008 | May 2009 |
| NCT00627458 | Completed | Phase 2 | Immunogenicity and Reactogenicity of a Booster Dose of GSK Bio's DTPa-HBV-IPV/Hib Vaccine | February 1, 2008 | August 18, 2008 |
| NCT00635128 | Completed | Phase 4 | Safety and Immunogenicity of a Booster Dose of GSK Biological's Boostrix-Polio Vaccine | February 1, 2008 | July 8, 2008 |
| NCT00654901 | Completed | Phase 3 | Study of the DTaP-IPV-Hep B-PRP~T Combined Vaccine Following a Primary Series of DTacP IPV-HepB-PRP-T or Infanrix Hexa™ | March 2008 | July 2009 |
| NCT00662870 | Completed | Phase 3 | Study of the Safety, Immunogenicity and Lot Comparability of DAPTACEL When Administered With Other Recommended Vaccine | May 2001 | January 2004 |
| NCT00674908 | Completed | Phase 4 | Phase IV Interchangeability Study of a Liquid Pentavalent Combination Vaccine | March 2008 | May 2009 |
| NCT00696423 | Completed | Phase 3 | Immunogenicity and Safety of GSK Biologicals' Infanrix/Hib in Children | June 7, 2008 | July 26, 2008 |
| NCT00707148 | Completed | Phase 1 | Pertussis Vaccine in Healthy Pregnant Women | January 2009 | May 2012 |
| NCT00712959 | Completed | Phase 4 | Immune Responses in Adults to Revaccination With ADACEL® 10 Years After a Previous Dose | June 2008 | December 2009 |
| NCT00753649 | Completed | Phase 4 | Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants | September 23, 2008 | March 12, 2013 |
| NCT00772369 | Completed | Retrospective Survey of Safety of Fourth Dose Pentacel® in Children | September 2003 | April 2005 | |
| NCT00772928 | Completed | Phase 3 | Study of the Effect of Pneumococcal Conjugate Vaccine (PCV) on Immunogenicity of Pentacel™ | October 2003 | November 2006 |
| NCT00777257 | Completed | Phase 4 | Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap Vaccine | April 2005 | September 2007 |
| NCT00797511 | Completed | Phase 3 | Immunogenicity and Safety of Adacel Polio Vaccine | November 2008 | July 2009 |
| NCT00802867 | Completed | Phase 4 | Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™ | February 2004 | September 2005 |
| NCT00804284 | Completed | Database Surveillance Safety Study of PENTACEL® Vaccine | September 2008 | January 2015 | |
| NCT00831311 | Completed | Phase 2 | Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared With PENTAXIM™ and ENGERIX B® PEDIATRICO in Argentinean Infants | October 2004 | March 2007 |
| NCT00831753 | Completed | Phase 3 | Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared to Infanrix®Hexa in Healthy Peruvian Infants | May 2008 | November 2009 |
| NCT00835237 | Completed | Phase 3 | Evaluation of GlaxoSmithKline Biologicals' Boostrix® Vaccine in Comparison With Decavac™ Vaccine. | February 17, 2009 | October 15, 2009 |
| NCT00855855 | Completed | Surveillance Program to Determine Product Specific Rates of Invasive Hib Disease | February 2009 | December 2014 | |
| NCT06302374 | Completed | Phase 1/Phase 2 | Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of GR2001 in Chinese Healthy Adults | March 4, 2023 | February 19, 2024 |
| NCT00109330 | Completed | Phase 3 | A Combined Tdap Vaccine Used As A Booster Compared To Licensed Td Vaccine | November 2002 | April 2004 |
| NCT00133445 | Completed | Phase 2 | Pentavalent DTaP-Hep B-IPV | December 2005 | August 2006 |
| NCT02569879 | Completed | Impact of Boostrix™ Maternal Vaccination on Morbidity and Mortality of Pertussis Disease in Infants ≤6 Weeks of Age, in Bogota, Colombia. | October 1, 2015 | April 14, 2018 | |
| NCT02587520 | Completed | Phase 1/Phase 2 | Study of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed in Healthy Subjects | October 22, 2015 | February 21, 2017 |
| NCT02817451 | Completed | Phase 3 | DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants | July 14, 2016 | February 22, 2019 |
| NCT02853929 | Completed | Phase 4 | Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery | September 19, 2016 | March 19, 2019 |
| NCT02858440 | Completed | Phase 3 | A Study to Assess the Immunogenicity and Safety of GSK Biologicals' Infanrix-IPV/Hib Vaccine Administered as a Three-dose Vaccination Course at 3, 4.5 and 6 Months of Age and a Booster Dose at 18 Months of Age in Healthy Infants in Russia | September 13, 2016 | November 13, 2018 |
| NCT02999815 | Completed | Phase 1/Phase 2 | Intrathecal Tetanus Immunoglobulin to Treat Tetanus | February 13, 2017 | May 1, 2020 |
| NCT03208101 | Completed | Phase 1 | A Study to Compare LBVD to Eupenta and Imovax Polio in Healthy Adults | July 3, 2017 | December 21, 2017 |
| NCT03266211 | Completed | Antitetanus Vaccination for People Older Than 65 Years. | November 9, 2017 | December 23, 2017 | |
| NCT03552445 | Completed | Phase 4 | Immunogenicity and Safety of a Tetanus-diphtheria Vaccine and a 13-valent Pneumococcal Conjugate Vaccine | November 1, 2013 | February 28, 2018 |
| NCT03589768 | Completed | Phase 2 | Study on the Safety and Immunogenicity of Boostrix Vaccine in Pregnant Malian Women and Their Infants | January 24, 2019 | July 1, 2020 |
| NCT03870061 | Completed | N/A | Evaluation of an Infant Immunization Encouragement Program in Nigeria | July 1, 2018 | February 20, 2020 |
| NCT03891758 | Completed | Phase 3 | Confirmatory Study of BK1310 in Healthy Infants | April 1, 2019 | August 10, 2020 |
| NCT03931239 | Completed | N/A | The Transparent Safety Study of the 5 in 1 (DTwP-rHepB-Hib) Combination Vaccine Produced by the Indian Serine Institute in Children of Viet Nam Healthy From 6 to 12 Weeks of Age in a 3-dose Regimen, the Interval Between Doses is 4 Weeks | March 1, 2018 | July 30, 2018 |
| NCT03950986 | Completed | N/A | Increasing Vaccine Uptake Among Veterans at the Atlanta VA Health Care System | October 15, 2018 | June 30, 2019 |
| NCT04099303 | Completed | Phase 1 | Phase I Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed . | April 28, 2020 | November 25, 2021 |
| NCT04142983 | Completed | Phase 2/Phase 3 | Tdap Vaccine Safety for Plasma Donors | February 3, 2020 | November 16, 2021 |
| NCT04165928 | Completed | Multicenter Study of Tetanus Patients in Fujian Province of China | July 1, 2018 | October 31, 2019 | |
| NCT04177485 | Completed | N/A | Evaluating a Caregiver SMS Reminder Intervention to Reduce Immunization Drop-out in Arua, Uganda | February 1, 2016 | December 4, 2017 |
| NCT04618939 | Completed | Phase 3 | To Evaluate the Immunogenicity and Safety of 'BR-TD-1001' Administered Intramuscularly in Healthy Children | October 20, 2016 | April 28, 2017 |
| NCT05625477 | Completed | Phase 2 | Study to Compare the Anti-tetanus Neutralizing Antibody Titers and Safety of TNM002 Injection With Human Tetanus Immunoglobulin or Placebo in Adult Volunteers | April 18, 2022 | October 18, 2022 |
| NCT05664750 | Completed | Phase 3 | Study to Compare the Efficacy and Safety of Passive Immunization With TNM002 Injection and Human Tetanus Immunoglobulin as Prophylaxis Against Tetanus | December 22, 2022 | July 7, 2023 |
| NCT06034093 | Completed | N/A | Real-time Artificial Intelligent (AI)-Assisted Muscle Ultrasound for Monitoring Muscle Mass Reduction in ICU Patients | June 1, 2020 | October 31, 2023 |
| NCT00092469 | Completed | Phase 3 | Study of an Investigational Vaccine in Healthy Infants in Taiwan (V441-001)(COMPLETED) | March 2002 | August 2003 |
| NCT00871000 | Completed | Phase 3 | Immunogenicity and Safety of Boostrix Polio Vaccine as a Booster Dose in 5 to 6-year-old Children. | April 1, 2009 | November 18, 2009 |
| NCT00871117 | Completed | Phase 3 | Immunogenicity and Safety of Kinrix + (Measles Mumps Rubella) MMR Vaccine With and Without Varicella Vaccine in Healthy Children 4-6 Years | March 31, 2009 | June 15, 2010 |
| NCT00879827 | Completed | Phase 3 | Immunogenicity and Reactogenicity of GSK Bio DTPa-HBV-IPV and Hib Vaccines When Coadministered to Healthy Infants | September 2000 | May 2001 |
| NCT00908115 | Completed | Post Market Surveillance for Infanrix™ | August 1, 2003 | June 23, 2008 | |
| NCT00964028 | Completed | Phase 3 | Safety Study of GSK Biologicals' DTPa-IPV/Hib (Infanrix™-IPV/Hib) | December 1, 2009 | April 12, 2010 |
| NCT00970307 | Completed | Phase 2 | Immunogenicity and Safety Study of GSK Biologicals' GSK2202083A Vaccine in Healthy Infants at 2, 3 and 4 Months of Age | August 13, 2009 | January 27, 2010 |
| NCT01031303 | Completed | Phase 4 | Immunogenicity and Safety of TETRAXIM™ Given as a Booster Dose at 4 to 6 Years of Age | December 2009 | January 2011 |
| NCT01040052 | Completed | Phase 3 | A Study to Assess the Safety of Adacel® Vaccine | December 2009 | April 2010 |
| NCT01062477 | Completed | Phase 3 | A Study of DTaP//PRP-T Combined Vaccine (ACTACEL) Versus Local DTaP and Act-HIB Monovalent Vaccine in Healthy Infants | January 2010 | December 2011 |
| NCT01086423 | Completed | Phase 3 | Immunogenicity and Safety Study of GSK Biologicals' Infanrix-IPV+Hib™ Vaccine | March 1, 2010 | November 19, 2010 |
| NCT01090453 | Completed | Phase 2 | Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants | May 17, 2010 | October 11, 2011 |
| NCT01105559 | Completed | Antibody Persistence in Healthy Children After Primary and Booster DTaP-IPV-Hep B-PRP-T Vaccine or Control Vaccine | April 2010 | December 2011 | |
| NCT01106092 | Completed | Phase 2 | Study to Evaluate the Immunogenicity and Reactogenicity of a Booster Dose of GSK2036874A Vaccine in Healthy Toddlers | May 13, 2010 | September 2, 2010 |
| NCT01137435 | Completed | Phase 4 | Post Marketing Surveillance for ADACEL™ in South Korea | June 2010 | September 2016 |
| NCT01147900 | Completed | Phase 4 | Evaluation of Boostrix™10 Years After Previous Booster Vaccination | June 15, 2010 | May 8, 2012 |
| NCT01171989 | Completed | Phase 2 | Immunogenicity and Safety Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine Administered as a Booster Dose | August 18, 2010 | December 3, 2010 |
| NCT01177722 | Completed | Phase 3 | A Study of DTaP-IPV-Hep B-PRP-T Vaccine Given With Prevenar™ and Rotarix™ in Healthy Latin American Infants | August 2010 | December 2011 |
| NCT01214889 | Completed | Phase 3 | Study of PENTAXIM™ Vaccine Versus TETRAXIM™ Vaccine Given With ACTHIB™ Vaccine in South Korean Infants. | September 2010 | December 2011 |
| NCT01245049 | Completed | Phase 3 | Immunogenicity and Safety of GSK Biologicals' Boostrix Polio Vaccine in 3 and 4-year-old Children | April 1, 2011 | April 2, 2012 |
| NCT01248884 | Completed | Phase 2 | Safety and Immunogenicity of New Formulations of GlaxoSmithKline Biologicals' DTPa-HBV-IPV/Hib Vaccine (GSK217744) | December 9, 2010 | January 5, 2012 |
| NCT01249183 | Completed | Phase 3 | Safety and Immunogenicity Study of Concomitant Versus Non Concomitant Administration of a Diphtheria, Tetanus, Pertussis and Poliomyelitis Vaccine (REPEVAX) and Influenza Vaccine (VAXIGRIP) in Subjects Aged From 60 Years Old | October 2010 | September 2011 |
| NCT01267058 | Completed | Phase 3 | Booster Study of Combined Diphtheria-tetanus-acellular Pertussis Vaccine in Healthy Adults | September 1997 | February 1998 |
| NCT01277705 | Completed | Phase 3 | Comparison of GSK Biologicals' Reduced Antigen Diphtheria and Tetanus Toxoids and Acellular Pertussis- Inactivated Poliovirus Vaccine, to BoostrixTM and Inactivated Poliovirus Vaccine Administered Separately and With Revaxis® | January 2002 | April 2002 |
| NCT01287949 | Completed | Phase 3 | Safety and Immunogenicity Study of a Diphtheria, Tetanus, Acellular Pertussis and Poliomyelitis Vaccine (REPEVAX) Followed by 2 Doses of a Diphtheria, Tetanus and Poliomyelitis Vaccine (REVAXIS) in Subjects of 40 Years of Age or Older | January 2011 | May 2012 |
| NCT01294605 | Completed | Phase 4 | Immunogenicity and Reactogenicity Study of BoostrixTM (dTpa) and Boostrix-IPV (dTpa-IPV) | April 2003 | September 2004 |
| NCT01309646 | Completed | Phase 3 | Immunogenicity and Safety of GlaxoSmithKline Biologicals' Infanrix™-IPV+Hib Vaccine | March 4, 2011 | February 24, 2012 |
| NCT01311557 | Completed | Phase 4 | Study of Adacel® Vaccine Administered to Persons 10 Years of Age | March 2011 | January 2012 |
| NCT01323959 | Completed | Phase 4 | Immunogenicity and Safety of Booster Dose of BoostrixTM Polio Vaccine in Previously Boosted Adults | April 1, 2011 | March 1, 2012 |
| NCT01331252 | Completed | N/A | Pneumonia in Tetanus Study | August 2000 | March 2002 |
| NCT01338688 | Completed | The Change of the Tetanus Antibody Titer After Single Injection of Td and Simultaneous Injection of TIG With Td | October 2008 | October 2010 | |
| NCT01346293 | Completed | Phase 3 | Study of DTap-IPV Compared to DAPTACEL® and IPOL® as the 5th Dose in Children 4 to 6 Years of Age | April 2011 | September 2013 |
| NCT01353703 | Completed | Phase 3 | Immunogenicity and Safety Study in Infants of GlaxoSmithKline Biologicals' Infanrix Hexa™ (DTPa-HBV-IPV/Hib) Vaccine | April 16, 2012 | February 25, 2013 |
| NCT01357720 | Completed | Phase 4 | Study to Assess if Quinvaxem Can be Interchanged With Other Pentavalent Vaccines During Standard Childhood Vaccination | May 2011 | September 2011 |
| NCT01358825 | Completed | Phase 4 | Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™ | May 30, 2011 | July 15, 2011 |
| NCT01362322 | Completed | Phase 4 | Immunogenicity and Safety of BoostrixTM Using a New Syringe in 10 to 15-year Old Adolescents | July 1, 2011 | September 3, 2012 |
| NCT01362517 | Completed | Phase 3 | Study of Quinvaxem for Vaccination Against Diphtheria, Pertussis, Tetanus, Hepatitis B and Diseases Caused by Haemophilus Influenzae Type B | April 2010 | April 2011 |
| NCT01437423 | Completed | Phase 4 | Regulatory Post-Marketing Surveillance Study for TETRAXIM™ | June 2011 | November 2015 |
| NCT01439165 | Completed | Phase 4 | Safety and Immunogenicity in Adults of Revaccination With Adacel® Vaccine 10 Years After a Previous Dose | November 2011 | February 2017 |
| NCT01444781 | Completed | Phase 3 | Study of the Booster Effect of DTaP-IPV-Hep B-PRP~T Combined Vaccine or Infanrix Hexa™ and Prevenar™ in Healthy Infants | September 2011 | October 2013 |
| NCT01449812 | Completed | Phase 3 | Immunogenicity and Safety Study of Booster Dose of GSK Biologicals' IPV (Poliorix™) and DTPa/Hib (Infanrix+Hib™) Vaccine | October 1, 2011 | January 16, 2012 |
| NCT01453998 | Completed | Phase 2 | Safety and Immunogenicity of a Booster Dose of New Formulations of GlaxoSmithKline Biologicals' DTPa-HBV-IPV/Hib Vaccine (GSK217744) | October 14, 2011 | November 12, 2012 |
| NCT01457495 | Completed | Phase 2 | Immunogenicity and Safety of DTPa-HBV-IPV/Hib Compared to DTPa-IPV/Hib and HBV Administered Concomitantly | September 1998 | September 1999 |
| NCT01457508 | Completed | Phase 3 | Immunogenicity and Reactogenicity of DTPa-HBV-IPV/Hib, Compared to DTPa-HBV-IPV and Hib Administered Separately | January 1999 | March 2000 |
| NCT01457547 | Completed | Phase 4 | Comparison of Immunogenicity and Reactogenicity of INFANRIX™ HEXA and HEXAVAC™ Vaccines as a Primary Vaccination Course | October 2003 | May 2005 |
| NCT01457560 | Completed | Phase 3 | Immunogenicity and Reactogenicity of DTPa-HBV-IPV/Hib Vaccine Followed by the Same Vaccine and Oral Polio Vaccine | February 2000 | April 2001 |
| NCT01470287 | Completed | Phase 3 | Immunogenicity, Safety and Tolerability of a Fully Liquid Pentavalent (DTwP-Hib-Hep B) Vaccine in Infants 6-8 Weeks of Age | December 2011 | April 2012 |
| NCT01491087 | Completed | Phase 4 | Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China | December 2011 | December 2012 |
| NCT01529645 | Completed | Phase 1 | Safety and Dose Ranging Study of Acellular Pertussis and Acellular Pertussis -Tetanus-Diphtheria Booster Vaccines in Healthy Adults Ages 18 to 40 Years | March 2012 | July 2013 |
| NCT01546909 | Completed | Phase 4 | Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRE | February 2012 | December 2012 |
| NCT01559597 | Completed | N/A | Comparative Study of Two Tetanus Toxoid Vaccination Strategies: Cold Chain Versus Controlled Temperature Chain | November 2012 | March 2013 |
| NCT01568060 | Completed | Post-marketing Surveillance to Assess the Safety of Infanrix-IPV Vaccine Among Infants and Children in Korea | May 21, 2012 | December 15, 2015 | |
| NCT01577732 | Completed | Phase 3 | Safety of GSK Biologicals' Infanrix-IPV+HibTM Vaccine in Healthy Vietnamese Toddlers | December 8, 2012 | April 9, 2013 |
| NCT01629589 | Completed | Phase 4 | Immunogenicity of Adacel® and BOOSTRIX® Vaccines in Adolescents | June 2012 | June 2013 |
| NCT01659996 | Completed | Phase 4 | Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age | July 2012 | September 2015 |
| NCT01689324 | Completed | Phase 1/Phase 2 | Study of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine (ADACEL®) as a Booster in Adolescents | September 2012 | May 2013 |
| NCT01711645 | Completed | Phase 4 | Tdap Vaccine in Post-Partum Women | October 26, 2012 | August 28, 2015 |
| NCT01738477 | Completed | Phase 3 | Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Previously Boosted Young Adults | January 31, 2013 | April 2, 2014 |
| NCT01878435 | Completed | N/A | Randomized Controlled Trial of the Impact of Mobile Phone Delivered Reminders and Travel Subsidies to Improve Childhood Immunization Coverage Rates and Timeliness in Western Kenya | October 2013 | February 2016 |
| NCT01890850 | Completed | Study to Analyze the Risk Factors Associated With Pertussis/Whooping Cough Infection Among Infants | July 2013 | November 2013 | |
| NCT01917357 | Completed | Phase 3 | A Comparison of the Immunogenicity and Safety of Quinvaxem in Mono-dose Vials and Uniject | September 2013 | April 2014 |
| NCT01933776 | Completed | Phase 1 | Study of the Tdap Combined Vaccine (ADACEL™) as a Booster Dose in Healthy Adults and Children in China | August 2013 | January 2014 |
| NCT01948193 | Completed | Phase 3 | Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine in Indian Infants Previously Given a Dose of Hepatitis B Vaccine at Birth | February 2014 | June 2015 |
| NCT01983540 | Completed | Phase 3 | Antibody Persistence at Age 3.5 and 4.5 Years After Primary and Booster DTaP-IPV-Hep B-PRP~T or Infanrix Hexa Vaccination | October 2013 | December 2015 |
| NCT01988857 | Completed | Phase 3 | Safety of a Booster Dose of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Healthy Vietnamese Children | February 22, 2014 | May 10, 2014 |
| NCT01993173 | Completed | Phase 3 | Sanofi Pasteur's Tdap Combined Vaccine as a Booster Versus Local DT Vaccine in Children or Versus Local Td Vaccine in Adolescents and Adults in China. | November 2013 | April 2015 |
| NCT02040636 | Completed | Phase 2 | Study of Tetanus and Diphtheria Toxoids Adsorbed Combined With Component Pertussis Vaccine and Inactivated Poliomyelitis | January 1999 | May 2000 |
| NCT02089347 | Completed | Phase 3 | Study of SP306 Given Intramuscularly Compared to DT Given Subcutaneously in Japanese Adolescents 11 - 12 Years Old | March 2014 | March 2015 |
| NCT02094833 | Completed | Phase 3 | DTaP-IPV-Hep B-PRP~T Combined Vaccine Versus DTaP-IPV//PRP~T Combined Vaccine + Hep B Vaccine in Hep B Primed Infants | March 2014 | November 2016 |
| NCT02096263 | Completed | Phase 3 | Study to Determine the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals; Infanrix Hexa at 2, 4 and 6 Months of Age in Healthy Infants | April 16, 2014 | November 13, 2015 |
| NCT02118961 | Completed | Phase 3 | Study of BK1301 (DTaP Vaccine) as a Booster in Adolescents | April 2014 | August 2014 |
| NCT02274285 | Completed | Phase 3 | DTaP-IPV/Hib Vaccine Primary & Booster Vaccinations Versus Co-administration of DTaP-IPV and Hib Vaccine in Japanese Infants | October 2014 | May 28, 2016 |
| NCT02422264 | Completed | Phase 4 | Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery | January 22, 2016 | March 7, 2018 |
| NCT02428491 | Completed | Phase 3 | Immunogenicity and Safety of Sanofi Pasteur's Combined Vaccine Given as a Three-Dose Primary Series at 2, 3,4 Months of Age and Followed by a Booster Dose Given at 16 to 17 Months of Age in Vietnamese Infants Who Previously Received a Dose of Hepatitis B Vaccine at Birth or Within 1 Week After Birth | April 20, 2015 | January 11, 2017 |
| NCT02447978 | Completed | Duration of Protection: GSK DTaP Vaccines | February 2015 | June 2015 | |
| NCT02458183 | Completed | Phase 3 | Vaccine -diphthEria -tetaNus -Acellular pertUssis-inactivated polioviruS | February 2, 2015 | May 5, 2018 |
| NCT02538211 | Completed | N/A | The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune Responses | September 2015 | February 2017 |
| NCT05457946 | Not yet recruiting | Phase 2/Phase 3 | Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series | April 1, 2023 | September 30, 2025 |
| NCT05952596 | Not yet recruiting | Phase 1 | A Study to Evaluate Safety and Immunogenicity of APV006 in Healthy Adults | July 17, 2023 | March 31, 2024 |
| NCT06056050 | Recruiting | Phase 1 | A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above) | December 6, 2023 | February 28, 2025 |
| NCT06049940 | Recruiting | Phase 3 | Safety and Immunogenicity of Tetanus Vaccine, Adsorbed in 18~44 Years Old Population | September 1, 2023 | March 30, 2025 |
| NCT06184542 | Recruiting | Phase 1 | Phase I Clinical Trial of Diphtheria-Tetanus-acellular Pertussis Component Combined Vaccine | December 23, 2023 | November 1, 2026 |
| NCT06120751 | Recruiting | Phase 3 | A Clinical Trial to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over | March 20, 2024 | July 2024 |
| NCT00316680 | Terminated | Phase 3 | Immuno & Safety Study With 2 Formulations of DTPw-HBV/HIB When Given at Birth With Hepatitis B at 2, 4 and 6 Mths.Age. | March 2006 | November 2006 |
| NCT00871741 | Terminated | Phase 2 | Feasibility Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants at 3, 5 and 11 Months of Age. | April 1, 2009 | June 25, 2009 |
| NCT00544271 | Terminated | Phase 4 | Immunogenicity, Antibody Persistence and Safety of GSK Biologicals' DTPa (INFANRIX) and dTpa (BOOSTRIX) Vaccines. | May 2003 | January 2004 |
| NCT00437671 | Terminated | Phase 4 | Tetanus Immunization in Subjects With No Immunization History or With Tetanus Antibody Levels Below Protective Levels | March 2007 | September 2007 |
| NCT02257645 | Unknown status | Post-authorization Safety Study of Euforvac-Hib Vaccine for Active Primary Immunization in Infants From 6 Weeks | March 2015 | September 2016 | |
| NCT03341195 | Unknown status | N/A | Mobile Phone SMS Messages and Automated Calls in Improving Vaccine Coverage Among Children in Pakistan | January 2018 | September 2018 |
| NCT04618640 | Unknown status | Phase 3 | To Evaluate the Immunogenicity and Safety of DTaP-IPV Vaccine Administered as a Boosting Dose to Healthy Children of 4-6 Years | December 26, 2019 | July 30, 2021 |
| NCT00877357 | Unknown status | Phase 4 | Safety, Long Term Immunogenicity and Lot Consistency Study of Liquid Pentavalent Combination Vaccine | January 2009 | February 2013 |
| NCT00932269 | Unknown status | Seroimmunity 2007 and Sub Study of the Swedish Population Regarding Vaccine Preventable Disease | March 2007 | September 2011 | |
| NCT04056728 | Unknown status | Phase 4 | A Phase IV Study to Assess the Safety of EupentaTM Inj | September 23, 2019 | December 31, 2020 |
| NCT02813486 | Unknown status | Phase 1/Phase 2 | Safety and Immunogenicity Study of Tetanus, Diphtheria and Acellular Pertussis (Tdap) Vaccine | June 2016 | November 2016 |
| NCT04073459 | Unknown status | Phase 2 | Safety and Immunogenicity of Hexavalent Vaccine(DTwP-HepB-IPV-Hib) in Healthy Infants | November 2019 | August 2020 |
| NCT04238975 | Unknown status | Phase 2 | A Study to Evaluate the Safety and Efficacy(Immunogenicity) of GC3111 in Healthy Adults | October 14, 2019 | May 2021 |
| NCT00870350 | Unknown status | Phase 4 | An Immunogenicity and Safety Study of Tetanus, Diphtheria and Acellular Pertussis Vaccine Booster | April 2009 | June 2010 |
| NCT01810731 | Withdrawn | Phase 2/Phase 3 | Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya | April 2014 | April 2014 |
| NCT01003431 | Withdrawn | Phase 3 | A Study of the Immunogenicity and Safety of Whole-Cell Pertussis Containing Vaccine Administered Concomitantly With RotaTeq™ (V260) or Rotarix™ (V260-036)(WITHDRAWN) | December 2009 | September 2010 |
| NCT03128489 | Withdrawn | Phase 3 | Evaluation of Immunogenicity and Safety of DTPa-IPV/Hib Conjugate Vaccine (Infanrix™-IPV/Hib) Administered at 6, 10 and 14 Weeks in Healthy Indian Infants | December 1, 2017 | August 1, 2018 |
- Disase is a (Disease Ontology)
- DOID:0050338
- Cross Reference ID (Disease Ontology)
- GARD:5144
- Cross Reference ID (Disease Ontology)
- ICD10CM:A35
- Cross Reference ID (Disease Ontology)
- ICD9CM:037
- Cross Reference ID (Disease Ontology)
- MESH:D013742
- Cross Reference ID (Disease Ontology)
- NCI:C85185
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154312006
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0039614
- Exact Synonym (Disease Ontology)
- clostridial tetanus
- Exact Synonym (Disease Ontology)
- Infection due to Clostridium tetani
- OrphaNumber from OrphaNet (Orphanet)
- 3299
- MeSH unique ID (MeSH (Medical Subject Headings))
- D013742