Annotation Detail

Information
Associated Genes
IL10
Associated Variants
IL10 MUTATION
IL10 MUTATION
Associated Disease
diffuse large B-cell lymphoma
Source Database
DisGeNET
Description
We hypothesized that DLBCLs depend for their proliferation and survival on IL10-STAT3 signaling and that blocking the IL10 receptor (IL10R) would induce cell death.
Pubmed
25733167
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.016178229846295
Drugs