candidiasis

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Information
Disease name
candidiasis
Disease ID
DOID:1508
Description
"An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons." [url:http\://en.wikipedia.org/wiki/Candidiasis, url:http\://mycology.adelaide.edu.au/Mycoses/Cutaneous/Candidiasis/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05707156 Completed Prospective Observational Study on the Incidence of Opportunistic Fungal Infections July 5, 2023 January 5, 2024
NCT00000744 Completed N/A A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women December 1995
NCT00000788 Completed Phase 1 A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone June 1994
NCT00001107 Completed Phase 4 Comparison of Two Treatments to Prevent Invasive Fungal Infections in Patients Who Have Received Liver Transplants November 2005
NCT00001542 Completed Phase 4 Fluconazole Prophylaxis of Thrush in AIDS July 1996 November 2001
NCT00001810 Completed Phase 3 An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections April 1999 October 2000
NCT00001937 Completed Phase 3 Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients November 1999 December 2000
NCT00002038 Completed N/A Non-Comparative Study of Fluconazole in Patients With Serious Mycoses and Who Cannot Be Treated With Conventional Antifungal Therapy
NCT00005912 Completed Phase 1 Voriconazole to Prevent Systemic Fungal Infections in Children June 2000 January 2001
NCT00036179 Completed Phase 2 Study of FK463 in the Treatment of Candidemia or Invasive Candidiasis February 27, 1999 January 27, 2002
NCT00037219 Completed Phase 2 The Safety and Effectiveness of Intravenous Anidulafungin as a Treatment for Patients With Invasive Candidiasis. August 2001 November 2002
NCT00041704 Completed Phase 2 The Safety and Efficacy of Intravenous Anidulafungin as a Treatment for Azole-Refractory Mucosal Candidiasis (FRMC) August 2002 August 2004
NCT00056368 Completed Phase 3 The Safety and Efficacy of Anidulafungin Versus Comparator in Patients With Candidemia and Invasive Candidiasis March 2003 October 2004
NCT00058682 Completed Phase 3 Anidulafungin Versus Fluconazole in the Treatment of Candidemia April 2003 January 2005
NCT00082524 Completed Phase 2 Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043) April 2004 July 2007
NCT00083343 Completed Phase 2 Caspofungin for the Treatment of Non-blood Candida Infections (0991-045) May 2004 February 2006
NCT01202253 Completed Early Clinical Experience With Anidulafungin In Patients With Liver Disease In The United Kingdom February 2011 May 2011
NCT01230814 Completed Phase 2 Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women April 2011 August 2013
NCT01273922 Completed Phase 1 Safety and Immunogenicity Study of a Recombinant Protein Vaccine (NDV-3) Against S.Aureus and Candida January 2011 December 2011
NCT01322698 Completed Staging Candidiasis in ICU Patients October 2011 October 2014
NCT01447407 Completed Phase 1 Effect of Adjuvant & Route of Administration on Safety & Immunogenicity of NDV-3 Vaccine September 2011 December 2012
NCT01919931 Completed Immunological Interaction Between the Host and Candida Albicans Biofilm March 2013 January 2016
NCT02391532 Completed N/A Effect of Probiotic Bacteria on Oral Candida in Frail Elderly September 2013 June 2015
NCT02493738 Completed Phase 1 A Clinical Study to Evaluate the Pharmacokinetics of Lozanoc and Sporanox in Korean Healthy Male Volunteers July 2015 October 2015
NCT02641717 Completed N/A Validity of Patient-Collected Wet Mounts November 2015 August 2016
NCT02666716 Completed Pharmacokinetics of Fluconazole IV as Prophylaxis or Therapy to ICU Patients May 2015 March 2016
NCT02860845 Completed Phase 4 Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections July 12, 2016 November 30, 2017
NCT03136081 Completed Candida Host Defense Response After Septic Shock in the Critically Ill June 2014 May 2015
NCT03203551 Completed N/A Clinical and Laboratorial Evaluation of the Desinfection Solutions in Candida Species From Total Prostheses and Palate of Total Edentulous. September 1, 2014 July 1, 2016
NCT04122560 Completed Phase 4 Fluconazole Pharmacokinetics, Including Bioavailability, in Obese Subjects After an Intravenous and Oral Administration November 30, 2019 March 23, 2021
NCT05044156 Completed Investigation of the Relationship Between Salivary Histatine-5 Level and Vaginal Candidiasis in Women October 21, 2021 March 6, 2022
NCT00000676 Completed Phase 3 Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081) November 1993
NCT00099775 Completed Phase 3 Caspofungin to Prevent Candidiasis in Adults in Hospital Intensive Care Units December 2004 September 2005
NCT00105144 Completed Phase 3 Study of Micafungin in Patients With Invasive Candidiasis or Candidemia September 2004 April 2006
NCT00106288 Completed Phase 3 Micafungin Versus AmBisome in Invasive Candidiasis and Candidemia January 2003 December 2005
NCT00109525 Completed Early Diagnosis of Candidiasis in Premature Infants March 2004 December 2009
NCT00138502 Completed Funguria in Hospitalized Patients September 17, 2001 December 8, 2008
NCT00163111 Completed Phase 3 A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood. September 1998 May 2003
NCT00313131 Completed Phase 3 Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments January 2004 May 2005
NCT00330395 Completed Phase 2 Open, Pharmacokinetic Study of Caspofungin in Neonates and Infants (0991-058) May 2006 October 2006
NCT00388167 Completed Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal Infection March 2004 February 2008
NCT00496197 Completed Phase 4 Study Will Evaluate The Safety And Efficacy Of Anidulafungin In Patients With Candidemia Or Invasive Candidiasis July 2007 June 2010
NCT00612963 Completed Novel Rinse to Treat in Oral Candidiasis in Cancer Patients April 2007 May 2009
NCT00647907 Completed Phase 4 A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections April 2003 May 2004
NCT00734539 Completed Phase 3 Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight November 2008 April 2013
NCT00739934 Completed Phase 2 Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infection December 2008 October 2009
NCT00784368 Completed Phase 3 A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection January 2008 May 2009
NCT00797420 Completed Phase 1 Pharmacokinetics (PK) Study of a Fluconazole Loading Dose in Infants and Toddlers November 2008 September 2011
NCT01102387 Completed Phase 2 Efficacy and Safety of LAS41003 in the Treatment of Intertriginous Candida Infections February 2010 July 2011
NCT03828773 Recruiting N/A PTX3-targeted Antifungal Prophylaxis February 11, 2019 November 30, 2025
NCT05235711 Recruiting The Role Of Interferon-gamma In Immune Responses To Invasive Candidiasis February 10, 2022 August 2024
NCT00805740 Terminated Phase 3 An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida April 2009 June 2012
NCT00692783 Terminated Incidence of Oral Candidiasis, Prevalence of C. Dubliniensis in HIV Patients and In-vitro Azole Susceptibility May 2008 January 2009
NCT00806351 Terminated Phase 3 An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune System August 2009 October 2011
NCT00815516 Terminated Phase 3 Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal Candidiasis February 2013 December 2014
NCT00095316 Terminated Phase 3 Caspofungin Study for Fungal Infections in Adults in Critical Care Settings October 2004 September 2006
NCT02646800 Terminated Phase 4 Post Marketing Study to Evaluate the Safety and Efficacy of Micafungin Against Fungal Infections Caused by Candida Spp or Aspergillus Spp March 21, 2014 December 21, 2014
NCT01092832 Terminated Phase 3 A Study Of The Safety, Tolerability And Effective Of Voriconazole For The Treatment Of Serious Candida Infection And Candida Infection Of The Throat In Pediatric Patients October 2010 June 2013
NCT01982071 Terminated Phase 4 A Study to Evaluate the Efficacy and Safety of Micafungin Against Invasive Candidiasis or Candidemia September 26, 2013 August 28, 2015
NCT04502277 Unknown status Early Phase 1 Bioavailability of Flucanazole September 1, 2020 January 31, 2021
NCT01315925 Unknown status Pre-hospital Risk Factors for Invasive Fungal Infection January 2010
NCT00889356 Unknown status Phase 3 Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis September 2009 March 2010
NCT02145832 Unknown status Phase 2/Phase 3 Fluconazole Versus Micafungin in Neonates With Candidiasis June 2014 May 2017
NCT01253954 Unknown status A Multicenter Observational Study of Invasive Candida Infections Among ICU Patients in China November 2009 April 2011
NCT00304772 Withdrawn Phase 4 Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients August 2006 December 2008
Disase is a (Disease Ontology)
DOID:2473
Cross Reference ID (Disease Ontology)
ICD10CM:B37
Cross Reference ID (Disease Ontology)
ICD9CM:112
Cross Reference ID (Disease Ontology)
MESH:D002177
Cross Reference ID (Disease Ontology)
NCI:C26711
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:154403005
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0006840
Exact Synonym (Disease Ontology)
Disseminated candidiasis
Exact Synonym (Disease Ontology)
systemic candidiasis
ICD10 preferred id (Insert disease from ICD10)
D0000633
ICD10 class code (Insert disease from ICD10)
B37
MeSH unique ID (MeSH (Medical Subject Headings))
D002177