schistosomiasis
Information
- Disease name
- schistosomiasis
- Disease ID
- DOID:1395
- Description
- "A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria." [url:http\://www.nlm.nih.gov/medlineplus/ency/article/001321.htm, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=schistosomiasis]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03187366 | Active, not recruiting | N/A | Schistosomiasis in Senegal | January 2, 2017 | September 2025 |
| NCT03910972 | Active, not recruiting | Phase 1/Phase 2 | Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults | October 7, 2019 | September 2024 |
| NCT06312462 | Active, not recruiting | N/A | Health Education Model Led by Community Health Volunteers. | January 1, 2024 | May 2025 |
| NCT00463593 | Completed | Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control Programmes | December 2006 | June 2007 | |
| NCT00463632 | Completed | Schistosomiasis in Women of Reproductive Age in Burkina Faso: Implications for Control | January 2007 | January 2009 | |
| NCT00463931 | Completed | Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana | September 2006 | January 2007 | |
| NCT00486863 | Completed | Phase 2 | S. Japonicum and Pregnancy Outcomes | August 2007 | November 2012 |
| NCT01154049 | Completed | Phase 1 | Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis | March 2011 | April 2014 |
| NCT01214876 | Completed | Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires | August 2010 | March 2011 | |
| NCT01288872 | Completed | Phase 1 | Praziquantel-Pharmacokinetic Study | January 2012 | August 2013 |
| NCT01424410 | Completed | Health Benefits of Repeated Treatment in Pediatric Schistosomiasis | February 2012 | November 2014 | |
| NCT01512277 | Completed | Phase 1 | Clinical Trial of Bilhvax,a Vaccine Candidate Against Schistosomiasis | September 1998 | September 1999 |
| NCT01553552 | Completed | Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal | October 2011 | October 2011 | |
| NCT01558336 | Completed | Phase 3 | Schistosoma Haematobium Infections and Praziquantel | August 2008 | September 2012 |
| NCT02105714 | Completed | Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders | July 2014 | May 2016 | |
| NCT02144389 | Completed | N/A | Arachidonic Acid Treatment Against Schistosomiasis Infection in Children | January 2013 | January 2014 |
| NCT02194712 | Completed | Detection of Schistosomiasis CAA in Travellers After High-risk Water Contact | January 2015 | September 2019 | |
| NCT02337855 | Completed | Phase 1 | A Phase I Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without GLA-AF for Intestinal Schistosomiasis in Healthy Adults | February 4, 2015 | January 27, 2017 |
| NCT02495909 | Completed | Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment | February 2016 | February 27, 2018 | |
| NCT05292391 | Completed | Phase 1 | Safety, Tolerability, and Immunogenicity Study of Sm-p80 + GLA-SE (SchistoShield(R)) Vaccine in Healthy Adults | May 23, 2022 | March 19, 2024 |
| NCT00276224 | Completed | N/A | Iron Supplementation in Schistosomiasis and Soil Transmitted Helminths Control Programmes in Zambia | September 2005 | April 2006 |
| NCT00463528 | Completed | Women and Children as the Focus for Control of Schistosomiasis Infections in the Irrigations Area of Burkina Faso | December 2006 | February 2007 | |
| NCT02755324 | Completed | N/A | Single-sex Controlled Human Schistosomiasis Infection: Safety and Dose Finding | October 27, 2016 | January 21, 2019 |
| NCT02806232 | Completed | Phase 2 | An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni) | June 12, 2016 | November 17, 2018 |
| NCT02868385 | Completed | Phase 3 | Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST) | October 1, 2018 | January 14, 2019 |
| NCT03041766 | Completed | Phase 2 | Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions | December 6, 2016 | June 2, 2017 |
| NCT03110757 | Completed | Phase 1 | A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed Adults | May 20, 2018 | November 14, 2019 |
| NCT03458338 | Completed | Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa | December 8, 2010 | May 30, 2011 | |
| NCT03799510 | Completed | Phase 2 | Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children | December 13, 2018 | August 7, 2019 |
| NCT03845140 | Completed | Phase 3 | L-PZQ ODT in Schistosoma Infected Children | September 2, 2019 | October 11, 2021 |
| NCT04115072 | Completed | Phase 2/Phase 3 | Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study | September 3, 2019 | February 21, 2020 |
| NCT04269915 | Completed | N/A | Single-sex Female Controlled Human Schistosomiasis Mansoni Infection | August 12, 2020 | December 12, 2022 |
| NCT04810741 | Completed | Retrospective Study of Clinical Practice and Management of Imported Schistosomiasis in France | December 21, 2021 | May 18, 2022 | |
| NCT05085470 | Completed | N/A | Repeated Controlled Human Schistosoma Mansoni Infection | October 29, 2021 | January 11, 2023 |
| NCT00215267 | Completed | N/A | The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda | September 2005 | October 2007 |
| NCT06182176 | Not yet recruiting | N/A | Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control | May 27, 2024 | January 12, 2026 |
| NCT05999825 | Not yet recruiting | Phase 2 | Sm-p80 Schistosomiasis Challenge Study | September 2024 | September 2025 |
| NCT05762393 | Recruiting | Phase 1 | A Study to Evaluate the Safety, Tolerability, and Immunogenicity of the Sm-p80 + GLA-SE (SchistoShield®) Candidate Vaccine in Healthy Adults in Burkina Faso and Madagascar | November 17, 2023 | December 1, 2024 |
| NCT05868005 | Recruiting | N/A | Delivering a Multi-disease Screening Tool to Migrant Populations | October 23, 2023 | September 2024 |
| NCT03158298 | Terminated | Seropositivity and Adverse Birth Events in Migrants From Bilharzia-endemic Areas | June 1, 2017 | October 11, 2019 | |
| NCT01260012 | Unknown status | N/A | Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis | January 2010 | December 2015 |
| NCT05354258 | Unknown status | N/A | Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children | June 16, 2022 | September 2023 |
| NCT01459146 | Unknown status | Phase 4 | Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana | December 2010 | November 2012 |
| NCT04589390 | Unknown status | Phase 2 | Selexipag for the Treatment of Schistosomiasis-Associated Pulmonary Arterial Hypertension | October 15, 2020 | March 31, 2022 |
| NCT04635553 | Unknown status | Monitoring Schistosome Hybrids Under Under Praziquantel Pressure | August 11, 2020 | December 31, 2022 | |
| NCT01869465 | Unknown status | N/A | Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis | October 2012 | June 2013 |
| NCT03640377 | Unknown status | Phase 2 | Praziquantel in Children Under Age 4 | February 1, 2021 | December 31, 2022 |
| NCT02734186 | Withdrawn | Phase 4 | Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis | April 6, 2016 | December 14, 2018 |
- Disase is a (Disease Ontology)
- DOID:883
- Cross Reference ID (Disease Ontology)
- GARD:9687
- Cross Reference ID (Disease Ontology)
- ICD9CM:120.8
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:187116001
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0029827
- OrphaNumber from OrphaNet (Orphanet)
- 1247
- MedGen concept unique identifier (MedGen Concept name)
- C1866993
- MedGen unique identifier (MedGen Concept name)
- 401132
- MeSH unique ID (MeSH (Medical Subject Headings))
- D012552