Annotation Detail

Information
Associated Genes
IL10
Associated Variants
IL10 MUTATION
IL10 MUTATION
Associated Disease
Allergic rhinitis (disorder)
Source Database
DisGeNET
Description
In vitro HDM challenge presents concordant patterns with in vivo findings: 1) increase of Th2 and Th17 response in AR patients; 2) suppression of IL10 producing CD4+ T cells in SIT-untreated AR but elevation in SIT-treated AR patients.
Pubmed
24647473
Section of the abstract supporting the evidence
UNLABELLED
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00453856695524446
Drugs