Periodontal Diseases

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Disease name
Periodontal Diseases
Disease ID
Description
Disease area statistics
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Annotation
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NCT ID Status Phase Summary Start date Completion date
NCT05812391 Active, not recruiting N/A Impact of Full Mouth Erythritol Powder Air Polishing on Systemic Inflammatory Response March 10, 2023 October 2024
NCT06191497 Active, not recruiting N/A The Effect of Smoking and Chlorhexidine on Periodontal Tissues After Non- Surgical Periodontal Therapy in Patients With Periodontitis March 14, 2022 May 1, 2024
NCT06049589 Active, not recruiting N/A Therapeutic Application of Coconut Oil in Oral Health November 1, 2022 August 2024
NCT06075680 Active, not recruiting N/A Effect of Periodontal Treatment on Inflammasome Proteins in Periodontal Diseases March 4, 2022 November 2023
NCT05878353 Active, not recruiting N/A Influence of Local Doxycycline on the Outcomes of Periodontal Regeneration March 1, 2023 February 15, 2024
NCT05798871 Active, not recruiting N/A Efficacy of Subgingival Erythritol Air Polishing in Treatment of Periodontal Pockets March 5, 2023 September 2024
NCT05739838 Active, not recruiting N/A Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients. April 1, 2021 May 2023
NCT06291129 Active, not recruiting N/A Gingival Health and Malocclusion Among Type 1 Diabetic Children and Adolescents October 30, 2022 October 30, 2024
NCT03836378 Active, not recruiting N/A Addition of Dehydrated Human Amnion-Chorion Membrane During Scaling and Root Planing November 1, 2020 November 1, 2027
NCT01742559 Completed N/A The Anesthetic Effect of Anterior Middle Superior Alveolar Technique January 2009 July 2011
NCT01852253 Completed N/A Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment March 2010 April 2013
NCT02066337 Completed Phase 2 Effect of Ozone Gel on Treatment of Chronic Periodontitis March 2013 February 2014
NCT02172716 Completed N/A Disruption of Immune Homeostasis in Type 2 Diabetics With Generalized Chronic Periodontitis May 2014 May 2016
NCT02185209 Completed Phase 4 Surgical Treatment of Peri-implantitis With and Without Systemically Adjunctive Antibiotics March 2015 May 27, 2022
NCT02375178 Completed N/A Antimicrobial Activity of Two Mouthwashes August 2014 December 2015
NCT02433405 Completed Serum Amyloid A Protein And Fetuin A Levels December 2013 November 2014
NCT02460926 Completed N/A Acute Phase Response & Periodontal Treatment May 2012 October 2014
NCT02461030 Completed Phase 4 Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment August 2014 December 2014
NCT02500654 Completed Phase 4 Regenerative Surgical Treatment of Peri-implantitis December 2008 January 2014
NCT02560870 Completed Phase 2/Phase 3 Compare the Efficacy of Aloe Vera Mouthwash With Non- Alcoholic Chlorhexidine Mouthwash on Periodontal Diseases March 2014 May 2015
NCT02613468 Completed N/A Periodontal Condition in Pregnancy and Low Birth Delivery Incidence January 2004 August 2005
NCT02615626 Completed Visfatin Levels Before and After Periodontal Treatment May 2012 January 2014
NCT02666573 Completed Phase 4 Photodynamic Therapy During Supportive Periodontal Therapy June 2013
NCT02756377 Completed Phase 2/Phase 3 A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases May 2014 June 2015
NCT02774967 Completed N/A Comparation Between Two Surgical Techniques With Acellular Dermal Matrix in Treatment of Gingival Recessions March 2014 January 2016
NCT02903264 Completed Gestational Diabetes Mellitus, Obesity and Periodontal Disease January 2007 September 2016
NCT02906982 Completed N/A Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis October 2015 April 2016
NCT02935868 Completed Periodontal and Salivary Evaluation of Type 1 Diabetes Mellitus Patients November 2013 September 2016
NCT02938988 Completed N/A Antimicrobial Photodynamic Therapy as an Adjunct Treatment for Periodontal Disease in Down's Syndrome Patients October 2013 October 2016
NCT02941887 Completed Global Behavior and Periodontal Disease in Down's Syndrome Patients October 2013 October 2016
NCT02982681 Completed Phase 3 Bioactive Glass and Platelet Rich Fibrin in Intrabony Defects April 2015 August 2016
NCT03671512 Completed N/A Standard Root Planing vs. Periodontal Structure Repair Device for Treatment of Pockets Caused by Periodontal Disease December 6, 2018 March 9, 2020
NCT00066066 Completed Phase 2 Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers July 2003 July 2009
NCT00127244 Completed Phase 2 Study Comparing Two Different Methods of Treating Periodontal Disease June 2000 October 2004
NCT00167466 Completed N/A Placebo Controlled Trial of a Titanium Dioxide Semiconductor Toothbrush on Mild-to-moderate Gum Disease October 2005 May 2010
NCT00255970 Completed Phase 2/Phase 3 Regenafil Versus Demineralized Freeze Dried Bone Allograft (DFDBA) for Periodontal Defects January 2006 November 2007
NCT01118143 Completed N/A Oral Health Literacy Tailored Communication June 2010 February 2012
NCT01215201 Completed N/A Diode Laser Study for Periodontal Maintenance Patients May 1, 2010 July 1, 2011
NCT01533792 Completed Phase 2 Effect of Non-surgical Periodontal Treatment March 2010 December 2010
NCT01728844 Completed N/A GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery October 2012 August 2014
NCT03590093 Completed N/A Amelogenins and Systemic Inflammation After Periodontal Surgical Therapy November 1, 2013 June 1, 2018
NCT03622255 Completed N/A Evaluation of Enamel Matrix Derivative as an Adjunct to Minimally Invasive Non-surgical Treatment of Intrabony Defects. May 5, 2018 March 15, 2021
NCT03628872 Completed N/A Treatment of Periodontitis With Er:YAG Laser March 2, 2018 June 1, 2019
NCT03648723 Completed The Effect of Periodontal Disease Treatment in Patients With Kidney Disease January 10, 2016 May 10, 2017
NCT03649789 Completed Periodontal Outcomes After Sanative Therapy August 1, 2018 May 1, 2019
NCT03660410 Completed Study of Oral Conditions in Indigenous Populations in the State of Roraima - Brazil March 2, 2017 October 2, 2017
NCT03663140 Completed Neurogenic Inflammation in Peri-implant and Periodontal Diseases January 1, 2011 December 30, 2013
NCT00066001 Completed Phase 2 Microbial Associations in Periodontal Health and Disease December 2002 December 2009
NCT03694496 Completed N/A The Effectiveness of an Oral Health Education Programme of Adolescents in Hong Kong September 1, 2018 October 31, 2020
NCT03715374 Completed N/A Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects November 6, 2017 December 12, 2018
NCT03721159 Completed Quantification of Micro-RNA 146-a in Chronic Periodontitis and Coronary Heart Disease Subjects October 1, 2017 October 1, 2018
NCT03729167 Completed N/A Instrumentation Effectiveness of Modified, Area-Specific Hand Scalers During Non-Surgical Periodontal Therapy November 9, 2018 June 17, 2019
NCT03753451 Completed N/A Influence of Periodontal Disease Treatment on Serum Levels of Sirtuin 1 and Mannose-binding Lectin October 1, 2016 October 1, 2018
NCT03764410 Completed N/A Evaluation of Non - Surgical Periodontal Therapy in Diabetic Patients. December 20, 2016 December 30, 2017
NCT03765151 Completed N/A The Effectiveness of Low-level Laser Therapy in Orthodontic Retention for Periodontal-compromised Patients October 1, 2018 December 1, 2020
NCT03787875 Completed Impact of Periodontal Treatment on the RANKL/OPG Ratio in Crevicular Fluid February 2, 2016 November 6, 2016
NCT03789565 Completed Hepcidin Levels in Periodontal Health and Disease March 15, 2017 February 15, 2018
NCT03790904 Completed Phase 2 Anti Plaque Efficacy of Salvadora Persica L. and Green Tea Mouthwash January 10, 2019 April 9, 2019
NCT03805724 Completed Entamoeba Gingivalis and Periodontal Disease July 13, 2018 January 18, 2019
NCT03809676 Completed Periodontal Status and Dental Behavior of Heart Trasplant Recipients and Healthy Controls January 9, 2018 January 10, 2019
NCT03839719 Completed N/A OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study. January 9, 2019 May 25, 2019
NCT03910205 Completed Tumor Necrosis Factor-alpha and Interleukin-18 Levels in Children With Gingivitis and Type 1 Diabetes Mellitus April 8, 2019 June 30, 2019
NCT03923465 Completed N/A Entire Papilla Preservation Technique With and Without Biomaterials in the Treatment of Isolated Intrabony Defects April 4, 2015 June 4, 2019
NCT03939936 Completed N/A The Effect of Periodontal Treatment on Psoriasis May 1, 2017 February 15, 2018
NCT03971981 Completed N/A Xylitol Chewing-gums: Concentration in Saliva and Antibacterial Effect February 1, 2018 May 28, 2019
NCT04017078 Completed Assessment of Carotid Artery Calcifications September 1, 2018 October 1, 2018
NCT04024644 Completed Third Molar: Caries, Periodontal Disease and Quality of Life May 1, 2013 May 1, 2014
NCT04036513 Completed N/A Minimally Invasive Non Surgical Therapy Versus Conventional Scaling and Root Planing for Treatment of Periodontitis April 2, 2019 April 2, 2021
NCT04045808 Completed Relationship of Oral Status to Coronary Artery Disease April 12, 2009 February 2, 2011
NCT04081025 Completed Oral Health and Risk Factors for Oral Disease January 1, 2018 January 31, 2023
NCT04082949 Completed Early Phase 1 Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis May 1, 2018 May 15, 2019
NCT04117451 Completed N/A The Effect of Propolis Mouthwash Compared to Chlorhexidine Mouthwash on Oral and Cardiovascular Health June 5, 2019 May 3, 2022
NCT04135222 Completed Evaluation of Periodontal Phenotype Using CBCT, Computed Aided Design (CAD) and Prosthetic-driven Implant Planing (PDIP). October 11, 2018 July 7, 2019
NCT04149327 Completed Phase 4 Systemic Amoxicillin Plus Metronidazole in Peri-implantitis Treatment August 1, 2012 December 2019
NCT04169139 Completed N/A Controlled Study Comparing REPaiR® and MIST Therapies for Treatment of Periodontitis May 18, 2018 May 15, 2020
NCT04173156 Completed N/A Treatment of Advanced Periodontitis Using an Oscillating Chitosan Device Versus Regular Curettes Alone October 1, 2017 December 19, 2019
NCT04180332 Completed N/A Anti Oxidant Enzymes and Total Antioxidant Levels in Diabetes Mellitus Type II Patients and Healthy Individuals With Periodontitis August 10, 2017 August 10, 2018
NCT04209231 Completed Effect of Vitamin D on Periodontal Disease November 2015 April 2016
NCT04209777 Completed Phase 3 Clinical Evaluation of Smoker Periodontal Subjects After Lactobacillus-reuteri Probiotics and Antibiotics Therapy July 8, 2018 May 6, 2019
NCT04253613 Completed Laser Biostimulation in Periodontal Treatment January 15, 2013 June 15, 2014
NCT04268381 Completed Oral and Systemic aMMP-8 in Periodontal Disease January 20, 2020 March 20, 2020
NCT04271787 Completed New Periodontal Classification March 1, 2019 November 4, 2019
NCT04332965 Completed N/A Periostin and Non-Surgical Periodontal Treatment January 2017 April 2018
NCT04335344 Completed Role of suPAR in Periodontitis and CVD February 15, 2015 February 25, 2020
NCT04345744 Completed N/A Evaluation of the Rinse With Chlorhexidine Plus Hyaluronic Acid Mouthwash in Periodontal Surgical Wound Healing January 2016 March 2020
NCT04356391 Completed N/A Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession January 24, 2018 April 26, 2023
NCT04380922 Completed Prevalence of Periodontal Diseases in IBD June 19, 2020 June 10, 2022
NCT04381273 Completed Oral Health and Psychosocial Factors During the Covid-19 Pandemic May 15, 2020 August 8, 2020
NCT04381403 Completed N/A Development of a New Toothpaste for the Removal of Dental Calculus. February 1, 2017 April 30, 2020
NCT04382105 Completed Evaluation of Saliva IL-6 Levels and Periodontitis November 8, 2015 September 25, 2019
NCT04390997 Completed N/A Determination of the Levels of Lipocalin-2 and Semaphorin3A November 15, 2019 January 15, 2021
NCT04399187 Completed N/A Adjunctive Local Sodium Hypochlorite Gel in Non Surgical Periodontal Debridement April 1, 2018 September 15, 2019
NCT04404335 Completed The Role of Anti-inflammatory Cytokines and Antimicrobial Peptide LL-37 Biomarkers in the Treatment of Periodontal Disease. May 17, 2021 July 15, 2022
NCT04404374 Completed N/A Treatment of Periodontal Intrabony Defects With A-PRF+ or EMD June 27, 2018 December 31, 2020
NCT04407026 Completed Oral and Systemic Levels of TFF-1 and TTF-3 in Periodontal Diseases July 1, 2017 April 1, 2018
NCT04417322 Completed Serum A.Actinomycetemcomitans Antibodies and Periodontitis April 15, 2016 March 25, 2020
NCT04422184 Completed Phase 4 Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients July 29, 2019 May 3, 2023
NCT04425343 Completed N/A Microbial Profiling in Pockets Related to Chronic Periodontitis Patients Using 16s RNA Metagenomics Sequencing November 10, 2017 October 7, 2019
NCT04450810 Completed Role of NLRP3 in Periodontitis and Diabetes June 1, 2014 September 30, 2017
NCT04450849 Completed Phase 4 Regenerative Potential of a Collagen Membrane Associated or Not to Bovine Bone in Class II Furcation Defects. January 10, 2018 January 20, 2020
NCT04470635 Completed Thiol/Disulphide Homeostasis and Vascular Endothelial Growth Factor Levels in Diabetic Children July 25, 2020 October 1, 2020
NCT04478864 Completed Knowledge, Practice and State of Periodontal Health September 27, 2020 November 30, 2021
NCT04509505 Completed Effect of Waterpipe Smoking on Periodontal Health November 1, 2020 October 30, 2021
NCT04556708 Completed N/A Ozonated Water Irrigation as an Adjunct to Periodontal Therapy April 1, 2019 March 1, 2020
NCT04564950 Completed Influence of Periodontitis and Coronary Heart Disease on Galectin-3 April 1, 2016 July 31, 2018
NCT04576468 Completed N/A The Use of Leucocyte Platelet Rich Fibrin (L- PRF) Covered Perforated Guided Tissue Membrane for Treatment of Periodontal Intrabony Defects June 1, 2018 December 31, 2019
NCT04581798 Completed Periodontal Disease in Patients With Obstructive Sleep Apnea April 12, 2021 January 15, 2022
NCT04637451 Completed N/A The Comparison of the Efficacy of Gingival Unit Graft With Connective Tissue Graft in Root Coverage July 1, 2015 July 30, 2016
NCT04646265 Completed N/A Effect of Periodontal Treatment on the Biomechanical Properties of the Periodontium. October 1, 2017 September 1, 2022
NCT04682275 Completed N/A Effect of Gender on Depression and Periodontal Status February 12, 2017 February 12, 2018
NCT04705714 Completed Phase 1 Antibacterial and Anti-biofilm Activity of Frankincense Extract Against Porphyromonas Gingivalis January 15, 2021 March 1, 2021
NCT04712630 Completed N/A Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft September 9, 2019 December 30, 2020
NCT04739475 Completed N/A Effect of Stress on Periodontal Therapy (NPT) March 1, 2021 December 20, 2021
NCT04777487 Completed N/A Evaluation of Biomarker Levels in Gingival Crevicular Fluid of Patients With Different Periodontal Diseases April 1, 2019 September 25, 2019
NCT04781478 Completed N/A Treatment of Periodontal Disease With Two Different Bioactive Gels for Home Oral Care March 16, 2021 October 15, 2021
NCT04802473 Completed N/A Flap Thickness Upon Root Coverage With the Use of Acellular Dermal Matrix July 9, 2020 April 22, 2022
NCT04809831 Completed N/A The Use of Biorepair Peribioma Toothpaste and Mousse for Home Oral Care in Patients Undergoing Periodontal Therapy March 22, 2021 November 3, 2021
NCT04815772 Completed Evaluation of the 1999 and 2018 Periodontal Disease Classifications: a Retrospective Study November 1, 2020 March 1, 2021
NCT04823572 Completed N/A Treatment of Periodontal Intrabony Defects With A-PRF or OFD February 1, 2020 February 28, 2024
NCT04845581 Completed Comparison of the Effectiveness of the USG and CBCT Combined With Intraoral Scanning Determing the Gingival Phenotype in the Healthy Periodontium October 11, 2018 August 2, 2019
NCT05046678 Completed miRNAs in Periodontal Disease March 1, 2019 November 1, 2020
NCT05108727 Completed N/A Diode Laser With Periodontal Flap Surgery in Periodontitis January 2013 March 2020
NCT05112471 Completed N/A Efficacy of GBT vs SRP+US, in the Treatment of Severe Generalized Periodontitis. November 22, 2016 April 4, 2020
NCT05129826 Completed N/A The Association Between Periodontal Disease and Malnutrition in a Group of Elderly People in Thailand. November 1, 2019 May 1, 2021
NCT05138484 Completed Phase 3 Clinical Evaluation of a Mouthwash Containing Malva Sylvestris Extract. October 20, 2017 January 14, 2019
NCT05140681 Completed N/A Influence of Flap Position Following FibReORS September 1, 2017 December 23, 2018
NCT05162417 Completed N/A Photodynamic in Periodontal Treatment November 15, 2021 April 1, 2023
NCT05211219 Completed N/A The Role of Probiotics in Periodontal Disease January 7, 2021 May 28, 2021
NCT05233501 Completed N/A Low-level Laser Therapy as an Adjunct to Non-surgical Periodontal Treatment January 1, 2017 August 30, 2018
NCT05254288 Completed N/A In-office and Domiciliary Use of a New Ozonized Gel for the Management of Periodontal Disease March 22, 2022 October 19, 2022
NCT05262153 Completed N/A Effect of Smoking on Periodontal Therapy in Periodontitis January 25, 2019 September 15, 2020
NCT05263622 Completed N/A Guided Biofilm Therapy for Periodontal Patients. March 22, 2022 September 2, 2022
NCT05275127 Completed Impact of Periodontal Treatment on Local miRNA Expression March 14, 2022 November 20, 2022
NCT05281796 Completed Evaluation of Galectin-3 Levels in GCF And Saliva of Patients With Different Periodontal Diseases January 22, 2022 August 15, 2023
NCT05281848 Completed N/A Effect of Smoking and Periodontal Therapy on Salivary and Gingival Crevicular IL-17 and IL-35 January 1, 2018 March 7, 2022
NCT05312606 Completed N/A Domiciliary Use of Hyaluronic Acid Gel Solutions vs Domiciliary Use of Chlorhexidine Mouthwash 0,20% for the Management of Periodontal Patients April 4, 2022 November 5, 2022
NCT05314192 Completed Non-invasive Assessment of Inflammatory Markers MIP-1 Alpha and IL-6 in Saliva of Post Myocardial Infarction and Stage 4 Periodontitis Patients March 1, 2021 April 20, 2021
NCT05325905 Completed Analysis of Gingival Crevicular Fluid October 2014 January 2017
NCT05336396 Completed N/A Impact of Brief Motivational Interviewing on Periodontal Clinical Outcomes: a 3-year Post-trial Follow-up May 20, 2019 March 25, 2023
NCT05372835 Completed N/A Hypochlorous Acid Mouthwash, Oral Bacteria, and Staphylococcus Aureus March 20, 2020 February 22, 2022
NCT05383794 Completed Role of miRNAs in CVD and Periodontitis April 1, 2019 December 15, 2021
NCT05394090 Completed N/A The Role of Periodontal Diseases and Stimulation of Saliva Secretion in the Acute Phase of Ischemic Stroke January 24, 2020 April 26, 2021
NCT05400538 Completed N/A Probiotics as Adjunct to Non Surgical Periodontal Therapy for Pregnant Women Oral Health June 10, 2022 October 20, 2023
NCT05435131 Completed N/A Evaluation of Biomarkers Levels in Gingival Crevicular Fluid, Saliva and Serum for Different Periodontal Diseases June 1, 2020 January 11, 2021
NCT05439785 Completed N/A Plaque Control Efficacy Between Interdental Brushes Versus Dental Floss April 1, 2022 May 30, 2022
NCT05496608 Completed N/A Treatment of Intrabony Defects With L-PRF Membrane With or Without Collagen Membranes January 1, 2021 February 1, 2022
NCT05513118 Completed Menopause and Oral Health March 1, 2019 October 31, 2019
NCT05562986 Completed N/A Impacts of Oral Irrigation in Orthodontic Patients March 1, 2018 December 27, 2018
NCT05576142 Completed Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma September 1, 2019 January 25, 2022
NCT05588544 Completed N/A YSGG Application in Periodontal Treatment May 26, 2020 June 29, 2021
NCT05590780 Completed Analysis of Cell-free DNA (cfDNA) During Periodontitis November 1, 2019 June 30, 2022
NCT05602545 Completed N/A Periodontal Status in Fermented Food and Food Consumption July 1, 2021 December 25, 2021
NCT05604703 Completed Comparison of Two Different Periodontal Classification April 1, 2021 April 15, 2022
NCT05622019 Completed Periodontitis, Sleep Quality and Fatigue March 1, 2022 June 15, 2022
NCT05631197 Completed N/A Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis March 2, 2022 September 30, 2023
NCT05631600 Completed Phase 2/Phase 3 Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study September 11, 2017 September 11, 2018
NCT05639582 Completed N/A Fractal Analysis Method in Periodontal Disease November 5, 2020 November 5, 2021
NCT05647902 Completed Association of Asprosin in Periodontitis and Acute Coronary Syndrome January 1, 2022 January 1, 2023
NCT05662475 Completed N/A Effect of Periodontal Treatment on Visfatin, fetuin-a and Sirtuin 1 of Patients With Periodontitis and Type 2 Diabetes November 15, 2021 July 15, 2022
NCT05702892 Completed N/A Evaluation of Bone Metabolism Biomarkers in Periodontal Diseases November 5, 2020 November 5, 2021
NCT05720481 Completed N/A Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels September 20, 2019 October 15, 2022
NCT05724251 Completed Effect of Iodine Deficiency on Periodontitis October 30, 2021 November 30, 2022
NCT05756946 Completed N/A Guided Tissue Regeneration With a Periodontal Dressing March 1, 2023 April 15, 2023
NCT05774925 Completed N/A Evaluation of Salivary Biomarker Levels of Individuals With Different Periodontal Diseases December 8, 2021 April 10, 2023
NCT05783011 Completed N/A The Effects of Electroacupuncture on Postoperative Pain March 30, 2021 December 30, 2022
NCT05787600 Completed Phase 3 Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide March 3, 2023 May 1, 2023
NCT05807100 Completed Investigation of Alzheimer's Disease and Periodontal Status March 2, 2022 January 6, 2023
NCT05809570 Completed Periodontal Disease Prediction System June 1, 2020 June 1, 2022
NCT05816941 Completed N/A Antimicrobial Photodynamic Therapy in Patients With Periodontal Disease and Type 2 Diabetes Mellitus January 3, 2016 January 3, 2019
NCT05846139 Completed N/A Slow-release Locally Administered 0.02% Hypochlorite Formulation January 17, 2022 November 21, 2022
NCT05849415 Completed Periodontal Health and Its Relationship With Psychological Stress February 28, 2023 February 18, 2024
NCT05862311 Completed N/A The Effect of Non-Surgical Periodontal Treatment on Bone Metabolism in Type 2 Diabetes and Systemically Healthy Individuals March 12, 2020 March 12, 2021
NCT05870059 Completed Phase 2 Comparative Evaluation of Propolis Mouthwash With 0.2% Chlorhexidine Mouthwash in Improving the Periodontitis February 2, 2022 November 16, 2022
NCT05924828 Completed sTREM-1, sTREM-2, Presepsin, and Periodontitis August 1, 2023 December 1, 2023
NCT05936450 Completed Phase 4 Assessment Of Healing After Periodontal Flap Surgery With And Without The Use Of Placental Extracts March 4, 2021 January 13, 2023
NCT05941611 Completed N/A Results From Objective Brushing Data Saved From a Powered Toothbrush Related to Values for Oral Health June 1, 2018 October 30, 2022
NCT05952921 Completed N/A Comparison of the Effectiveness of Hypochlorous Acid and Chlorhexidine as a Post-surgical Antimicrobial Agent July 10, 2019 December 15, 2019
NCT06002997 Completed Periodontal Status and Pregnancy or Delivery Complications in Type 1 Diabetes Mellitus Pregnant Women May 3, 2012 December 1, 2014
NCT06011564 Completed N/A eDENT Oral Health- the Gateway to Quality of Care and Everyday Life at Old Age June 1, 2018 January 15, 2023
NCT06040944 Completed Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients September 1, 2022 November 1, 2022
NCT06073613 Completed Periodontal Status in Patients With Chronic Skin Diseases January 20, 2023 April 28, 2023
NCT06081816 Completed Third Molar: Caries, Periodontal Desease and Quality of Life May 1, 2013 May 1, 2014
NCT06102616 Completed N/A Osteocalcin Level in Gingival Clavicular Fluid During Canine Retraction in Periodontal Compromised Patients January 14, 2022 August 23, 2023
NCT06145685 Completed N/A Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy January 1, 2021 February 28, 2022
NCT06184412 Completed Periodontal Status and Endothelial Dysfunction in Patients With Polycystic Ovary Syndrome February 1, 2020 September 1, 2022
NCT06199440 Completed Phase 1/Phase 2 Azithromycin Versus Doxycycline on Restistin Level in Periodontitis Patients With Type 2 Diabetes June 1, 2022 March 30, 2023
NCT06236555 Completed N/A Exploring 8-iso Prostaglandin F2α and Adenosine Deaminase Levels in Periodontal Health and Disease October 1, 2023 January 15, 2024
NCT06247007 Completed N/A Electroacupuncture as an Adjunct to Non-Surgical Periodontal Therapy August 1, 2023 December 1, 2023
NCT06250764 Completed Asprosin, Adropin, Irisin Levels in Periodontitis February 12, 2020 February 23, 2022
NCT06253988 Completed Phase 3 Effect of Probiotics on Periodontitis Stage III Grade C Molar-incisor Pattern January 1, 2023 September 30, 2023
NCT06291454 Completed GCF Levels of Chemokines in Periodontitis January 1, 2023 December 1, 2023
NCT06293807 Completed Early Phase 1 Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine June 6, 2022 April 16, 2023
NCT06306937 Completed Serum Levels of Vitamin D and IL8 in Patients With Periodontitis September 1, 2022 September 30, 2023
NCT06316505 Completed N/A Oral Photographs of Patients on Oral Hygiene Motivation December 1, 2023 March 1, 2024
NCT06343337 Completed N/A The Effects of Pregnancy on Oral Health May 20, 2022 April 1, 2023
NCT06354972 Completed Impact of SASP in the GCF on the Outcomes of Periodontal Regeneration January 2, 2022 January 2, 2024
NCT06379022 Completed Proteomic Analysis of Newly Restored Single Implants December 3, 2018 November 29, 2019
NCT06384638 Completed Phase 1 Coconut Oil in Treatment of Periodontitis February 15, 2022 February 9, 2024
NCT06408454 Completed Interleukin- 17 (IL-17), Bcl-3, and NF-kappa-B Inhibitor Zeta (IκBζ) Expression Levels in the Psoriasis Patients February 1, 2023 August 15, 2023
NCT06463535 Completed N/A Effects of Omega-3 as an Adjunct to Non-Surgical Periodontal Therapy on Chemerin Level in Periodontitis Patients With Diabetes: A Randomized Clinical Trial June 15, 2023 June 1, 2024
NCT03064178 Completed Use of Pain Medication Following Periodontal Procedures May 10, 2014 August 15, 2016
NCT03088228 Completed Maternal Periodontal Status and Cytokines in Preeclampsia February 2, 2015 December 31, 2016
NCT03095976 Completed N/A Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration June 14, 2017 September 10, 2019
NCT03122977 Completed N/A Acute-phase Response & Periodontal Treatment in Obese Patients June 1, 2016 October 1, 2021
NCT03132207 Completed The 4th Month Oral Consultation at Pregnant Women June 1, 2017 March 16, 2018
NCT03161301 Completed Role of IL-37 Genetic Variants in Modulating Innate Immune Response to Periodontal Pathogens May 7, 2015 May 24, 2019
NCT03191721 Completed Phase 3 Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment. June 2010 June 2017
NCT03196648 Completed N/A Randomized Trial of a Gum Health Formulation May 1, 2015 November 30, 2016
NCT03197610 Completed N/A The Effect of Enamel Matrix Derivatives on Root Coverage Esthetic Score January 1, 2015 September 1, 2016
NCT03219840 Completed Phase 4 Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis October 18, 2017 September 8, 2018
NCT03225950 Completed Interaction Between Immune Cells and Bacteria Associated With Periodontitis February 1, 2017 March 23, 2020
NCT03241953 Completed N/A COMPARISION OF DIFFERENT TREATMENT METHODS OF PERI-IMPLANTITIS April 23, 2014 December 22, 2016
NCT03244943 Completed N/A Cytokine Profiles in Breast Cancer Patients Undergoing Chemotherapy August 1, 2015 July 31, 2017
NCT03262402 Completed N/A Effects of Periodontal Treatment on HIV-infected Patients July 2, 2017 April 8, 2019
NCT03264118 Completed N/A Effects of Antimicrobial Photodynamic Therapy on Regeneration of Class II Furcation Lesions April 2, 2017 December 22, 2018
NCT03265821 Completed Influence of Smoking on Periodontal Healing One Year After Active Treatment January 2015 December 2015
NCT03316755 Completed N/A Risk Perception of Periodontal Disease March 1, 2017 October 7, 2017
NCT03336957 Completed N/A Stress and Gingival Inflammation in Non-pregnant and Pregnant Women June 1, 2016 January 1, 2017
NCT03345329 Completed Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms October 1, 2015 September 30, 2016
NCT03364751 Completed N/A Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome November 7, 2017 June 12, 2019
NCT03368430 Completed Phase 4 Melatonin as an Adjunctive Therapy for Chronic Periodontitis. July 4, 2016 September 7, 2017
NCT03371446 Completed DNA Methylation Profile of the SOCS-1 Gene Promoter in Smokers Patients With Chronic Periodontitis. June 6, 2016 November 18, 2017
NCT03386877 Completed N/A Periodontal Regeneration Using Dental Pulp Stem Cells (DPSCs) January 25, 2016 April 28, 2017
NCT03391349 Completed Quantification of Proteomes: L-plastin , Lipocalin and Adiponectin in Chronic Periodontitis and Diabetic Subjects October 20, 2016 December 1, 2017
NCT03395041 Completed Periodontal Disease, Inflammation and Acute Coronary Syndromes May 15, 2018 June 1, 2021
NCT03407911 Completed Microbiota Around Periodontal Teeth and Implants Affected by Peri-implant Disease. February 1, 2018 June 1, 2018
NCT03437798 Completed Genomic Determinants and Shared Genetic Pathways of Periodontal Disease January 30, 2018 December 31, 2023
NCT03442920 Completed N/A Evaluation of Periodontal Diseases and Obesity in Women December 29, 2014 January 10, 2016
NCT03452891 Completed Phase 4 Effect of Locally-Applied Simvastatin on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients March 1, 2019 December 31, 2020
NCT03459638 Completed Periodontitis as Signal for an Underlying Disease March 9, 2018 April 1, 2020
NCT03474146 Completed N/A Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract April 12, 2017 July 31, 2017
NCT03501316 Completed N/A The Immune Response After Periodontal Treatment May 1, 2018 September 1, 2019
NCT03507868 Completed YKL-40 and IL-6 Levels in Periodontal Disease September 2016 January 2018
NCT03527901 Completed Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease March 1, 2015 June 1, 2016
NCT03544931 Completed N/A Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy December 1, 2015 June 1, 2018
NCT03549247 Completed Oral Health Related Quality of Life and Periodontal Diseases November 11, 2015 October 27, 2017
NCT03550651 Completed N/A Evaluation of Antiplaque Efficacy of Licorice Extract Mouthrinse & HSS and Their Comparison With EO & CHX Mouthrinse August 2016 June 10, 2017
NCT03558906 Completed TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases March 1, 2016 December 26, 2016
NCT05932017 Enrolling by invitation Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization July 1, 2023 March 2025
NCT06122636 Enrolling by invitation N/A Efficacy of a Probiotic and Microbiological Analysis on Oral Complications Induced by Antineoplastic Therapies in Patients With HNC October 3, 2022 December 2024
NCT05636683 Enrolling by invitation N/A Bone Remodeling and Non-surgical Periodontal Therapy February 1, 2022 March 1, 2023
NCT06358963 Enrolling by invitation N/A CoQ10 and Omega-3 as Adjuncts to Periodontal Therapy, TAC of Saliva. February 20, 2024 May 10, 2024
NCT06308497 Enrolling by invitation N/A Adjunctive Periodontal Treatment With Coenzyme Q10 in Association With Probiotics for Pregnant Women March 10, 2024 October 20, 2024
NCT05125835 Enrolling by invitation Periodontal Maintenance and the COVID-19 Pandemic November 21, 2021 August 31, 2023
NCT06311253 Enrolling by invitation N/A Non-surgical Periodontal Treatment With Adjunctive Use of Lactoferrin Contained in Toothpaste and Mouthwash March 20, 2024 November 2024
NCT06373848 Enrolling by invitation N/A Comparison of Salivary Parameters in Patients Receiving CoQ10 and Vitamin E Supplementation March 20, 2024 September 15, 2024
NCT05178563 Not yet recruiting N/A Mechanisms of Acute Inflammation Following Periodontal Treatment September 1, 2024 December 31, 2026
NCT06309719 Not yet recruiting N/A Hyaluronic Acid and Polynucleotides for Supra-bony Defects May 2024 November 2025
NCT05569525 Not yet recruiting N/A Type I Diabetes and Non-surgical Periodontal Treatment November 6, 2022 May 10, 2024
NCT05858411 Not yet recruiting N/A Efficacy of rhPDGF as an Adjunct to Non-surgical Periodontal Therapy of Intrabony Defects May 8, 2023 December 16, 2024
NCT05828368 Not yet recruiting N/A DKK-3 rs11544814 and CFH rs10737680 Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CAD June 1, 2023 April 30, 2025
NCT05721313 Not yet recruiting N/A Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study September 1, 2023 January 15, 2025
NCT05869981 Not yet recruiting Association Between Periodontal Status and Mental Health in Postpartum Women June 7, 2023 October 7, 2023
NCT05546788 Not yet recruiting Phase 1 Hydroxylated Polymethoxy Flavones Solid Dispersion in Treatment of Periodontitis October 20, 2023 November 20, 2023
NCT06201975 Not yet recruiting N/A Efficacy of Thyme Honey as a Novel Adjunct to Non-surgical Periodontal Therapy January 1, 2024 February 20, 2024
NCT06116487 Not yet recruiting MRI as Alternative to CBCT for the Assessment of Furcation Involvement in Molars November 20, 2023 December 20, 2024
NCT05398770 Not yet recruiting N/A Randomized Clinical Trial (RCT) on the Effect of Vitamin D Supplement Prior to Non-surgical Periodontal Therapy: a Feasibility Trial August 2022 December 2024
NCT06430450 Not yet recruiting Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With Different Degrees of Periodontal Disease July 15, 2024 January 15, 2025
NCT05060601 Not yet recruiting N/A Minimally Non Surgical Periodontal Therapy Compared to Traditional Approach March 1, 2024 October 1, 2024
NCT06435208 Not yet recruiting N/A Impact of Subgingival Instrumentation on Psychological Distress and Mental Health Status in Bruxers With Periodontitis June 1, 2024 February 1, 2025
NCT06315855 Not yet recruiting N/A Leveraging Telehealth to Improve Oral Health Among Cancer Survivors June 25, 2024 August 25, 2027
NCT06315088 Not yet recruiting N/A Food Biodiversity and Human Health October 1, 2024 March 1, 2025
NCT05657171 Not yet recruiting "Effect of CPA/EE Drug on Periodontal Tissue and hsCRP Levels in PCOS Patients With Gingivitis December 12, 2022 July 15, 2023
NCT06188884 Not yet recruiting Staging and Grading of Periodontitis: Five Years Later June 1, 2024 August 31, 2024
NCT06071338 Not yet recruiting A Decision Support System Based on Classification Algorithms for the Diagnosis of Periodontal Disease October 1, 2023 December 30, 2024
NCT06031896 Not yet recruiting The Severity of Periodontitis at the Buccal and Palatal Site October 1, 2023 December 31, 2025
NCT04328389 Not yet recruiting N/A Periodontal Management in Hypertensive Patients (PERIOTENSION Trial I) June 2024 December 2024
NCT06162832 Recruiting Phase 2 Periodontal Regeneration With Recombinant Human Platelet Derived Growth Factor (rH-PDGF-BB) and Allograft January 10, 2024 January 15, 2025
NCT05813236 Recruiting N/A NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery June 28, 2023 July 2025
NCT06261723 Recruiting Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective February 15, 2024 December 31, 2025
NCT05838209 Recruiting N/A Effect of Ozone Oil After Non-surgical Periodontal Treatment April 5, 2023 July 1, 2023
NCT06290414 Recruiting The Accuracy of Infrared Thermographic Imaging for Assessment of Periodontal Status November 30, 2023 July 30, 2024
NCT04790825 Recruiting N/A Periodontal Therapy on the Gut Microbiome of Inflammatory Bowel Disease May 2, 2021 May 15, 2023
NCT06459037 Recruiting N/A Comparison of Salivary Neuropilin-1 (NRP-1), Cotinine and C-Reactive Protein (CRP) Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases May 10, 2024 April 14, 2025
NCT05864768 Recruiting N/A The Role of Diet in Periodontal Inflammation: A Controlled Clinical Study April 1, 2023 May 30, 2024
NCT04946292 Recruiting N/A Empowering Older Adults for Healthy Living and Better Dental Health March 29, 2022 June 2024
NCT05031923 Recruiting N/A Treatment of Intrabony Defects With Simvastatin and Antimicrobial Photodynamic Therapy October 16, 2021 August 2024
NCT06402877 Recruiting N/A Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases April 26, 2024 November 24, 2025
NCT05078411 Recruiting N/A Efficacy of Periodontal Risk Communication in Patients With and Without History of Tooth Loss December 1, 2021 December 31, 2022
NCT05890807 Recruiting N/A Concordance in Diagnosis of Periodontitis in Diabetic Patients Between an Indirect Method Based on a Photograph of the Oral Cavity and a Direct Method Based on the Clinical Examination of This Oral Cavity (Reference). March 20, 2023 September 1, 2024
NCT05119283 Recruiting N/A Clinical Study of a Formulation Containing Phtalox® in Periodontal Disease March 7, 2022 April 30, 2025
NCT06296498 Recruiting N/A Application of L-PRF in Periodontal Surgery August 19, 2023 March 2026
NCT06306677 Recruiting Accuracy of an AI-clinical Knowledge-based Hybrid System for Detecting Periodontitis in OPG Images March 12, 2024 December 31, 2024
NCT05940714 Recruiting N/A Periodontopathogens of Periodontal Patients May 15, 2023 October 15, 2024
NCT06404476 Recruiting N/A Evaluation of Salivary Galectin-8, Galectin-9 and RANKL Levels of Individuals With Different Periodontal Diseases May 3, 2024 June 24, 2025
NCT05212766 Recruiting Role of the Oral Microbiome & Mucosal Immunity in COVID-19 Disease April 7, 2022 December 30, 2024
NCT05948722 Recruiting N/A Behavioral Intervention Program Based on Motivational Interview May 2, 2023 September 1, 2024
NCT05252000 Recruiting N/A Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease April 26, 2022 July 1, 2024
NCT06025955 Recruiting N/A Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement. September 15, 2023 February 28, 2025
NCT06029283 Recruiting N/A Dietary Nitrate Functional Gum Effect on Gingivitis and Heart Health April 15, 2024 August 30, 2024
NCT06313216 Recruiting N/A Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate March 15, 2024 April 15, 2025
NCT06052150 Recruiting Oral Health In Cirrhosis of the Liver (ORACLE) September 18, 2023 December 31, 2024
NCT05339178 Recruiting Quality of Life of Periodontitis Patients Visiting Supportive Periodontal Therapy January 10, 2022 December 2033
NCT05384132 Recruiting N/A Novel Dental Gel as an Adjunct to Scaling and Root Planing October 14, 2022 October 2025
NCT06083649 Recruiting N/A The Dental Care Revolution: Health Education Using AI or Humanized Counseling on Plague Control and Periodontal Treatment Outcome in Patients With Periodontal Disease August 10, 2020 December 31, 2023
NCT03934957 Recruiting Hamburg City Health Study - a German Cohort Study February 8, 2016 December 31, 2028
NCT05418621 Recruiting Phase 3 Does the Non-surgical Application of Enamel Matrix Derivative Reduce the Need of Periodontal Surgical Intervention in Subjects With Severe (Stage III) Periodontitis? March 1, 2021 June 2025
NCT05425784 Recruiting N/A Home Use of Dual-light Photodynamic Therapy for Chronic Periodontitis January 19, 2023 February 28, 2025
NCT03997552 Recruiting N/A NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration September 6, 2019 December 1, 2024
NCT06086821 Recruiting N/A Clinical Relevance of Different Time of Periodontal Re-evaluation September 1, 2023 May 1, 2025
NCT06465095 Recruiting Evaluation of Inflammasome Gene Polymorphisms in Periodontitis Patients July 1, 2024 April 14, 2025
NCT06110143 Recruiting N/A Oral Health and Adverse Pregnancy Complications November 13, 2021 May 2026
NCT05511454 Recruiting N/A Comparison of Salivary and Crevicular Protein Concentrations of FIBA, PLMN, HEMO and ApoH in Healthy and Periodontitis Patients June 22, 2023 March 1, 2025
NCT05533528 Recruiting N/A Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment May 3, 2022 March 1, 2025
NCT05538078 Recruiting N/A Ozone Gel Application in Controlled Type 2 Diabetic Patients With Periodontitis October 15, 2022 August 2, 2023
NCT05541614 Recruiting N/A Flapless Application of Enamel Matrix Derivative in Class II Mandibular Furcation Defects October 15, 2022 April 15, 2025
NCT05543434 Recruiting N/A Application of Hyaluronic Acid in Diabetes December 1, 2022 December 1, 2023
NCT06125561 Recruiting Periodontal Health and Its Impact on Oral Health-related Quality of Life Among Diabetes Mellitus Patients October 1, 2023 November 8, 2023
NCT06129097 Recruiting N/A Thyme Honey Mouthwash in Management of Periodontitis in Renal Patients January 1, 2024 March 1, 2024
NCT04254861 Recruiting N/A Autologous Platelet Concentrate (APC) in Intrabony Defects March 2, 2021 May 15, 2025
NCT06131021 Recruiting Phase 3 Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice April 25, 2024 May 26, 2026
NCT06141083 Recruiting N/A Effect of TCI188 Probiotic on Oral Health November 1, 2023 November 30, 2024
NCT06428149 Recruiting N/A Three Types of Papilla Incision in Periodontal Surgery June 1, 2023 December 1, 2024
NCT06149585 Recruiting Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement August 16, 2023 May 1, 2026
NCT06349330 Recruiting N/A The Immediate Effectiveness of a 3D Intraoral Scanner as an Oral Hygiene Educational Tool November 7, 2023 July 31, 2024
NCT06186908 Recruiting N/A Evaluation of Salivary Gal-7, Gal-10 and MMP-9 Levels of Individuals With Different Periodontal Diseases May 2, 2024 March 24, 2025
NCT05691426 Recruiting Assessment of the Effect of Non-surgical Periodontal Treatment on Endothelial Function- a Prospective Study October 1, 2022 June 2024
NCT05706493 Recruiting N/A Association Between Periodontitis and the Level of Anti-citrullinated Protein Antibodies in Rheumatoid Arthritis March 1, 2024 August 2025
NCT06224699 Recruiting N/A Toothpaste With Sodium Carbonate in Patients With Gingivitis September 1, 2023 March 1, 2024
NCT05745324 Recruiting N/A The Effect of Scaling and Root Planing on Oral Inflammatory Biomarkers Among E-cig Users and Non-smokers June 1, 2022 December 1, 2023
NCT05746676 Recruiting Phase 3 Insulin Versus Hyaluronic Acid in Management of Periodontal Defects January 12, 2023 October 2023
NCT06235021 Recruiting N/A Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease January 1, 2024 March 1, 2024
NCT04478643 Recruiting N/A Lactobacillus Reuteri in the Supportive Therapy of Periodontitis October 7, 2020 June 2024
NCT05773911 Recruiting N/A Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel March 23, 2023 December 31, 2024
NCT06358937 Recruiting N/A Clinical and Microbiological Evaluation of Laser Assisted New Attachment Procedure (LANAP) Using Nd:Yag vs. Diode Laser in the Management Of Stage II Periodontitis November 1, 2023 May 2024
NCT04565691 Recruiting N/A Bacteremia From Periodontal Treatment to Elucidate the Underpinnings of Sepsis February 25, 2019 December 31, 2027
NCT05809427 Recruiting N/A High Frequency Intraoral Ultrasound Probe for Early Diagnosis of Periodontal Diseases July 7, 2023 May 2024
NCT04645693 Recruiting The Impact of Oral Health in HIV Patients on Antiretroviral Therapy February 24, 2021 March 2025
NCT04669717 Recruiting Phase 4 Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies September 1, 2021 December 1, 2026
NCT06253910 Terminated N/A Comparison of Free Gingival Graft and Modified Apical Repositioning Flap Techniques February 15, 2019 December 1, 2023
NCT04059458 Terminated Phase 4 Mandibular Furcation III Regeneration (FURC-III-REGEN) October 15, 2019 November 27, 2023
NCT03102892 Terminated N/A Antimicrobial Photodynamic Therapy on Periodontal Treatment and Salivary Status of Type 1 Diabetes Mellitus Patients April 24, 2017 March 13, 2020
NCT04059445 Terminated Phase 4 Mandibular Furcation II Regeneration October 15, 2019 November 27, 2023
NCT00116974 Terminated Phase 3 Periodontal Infection and Prematurity Study October 2004 February 2009
NCT01614925 Terminated Safety and Efficacy of Periodontal Surgery in Supra-alveolar-type Defects With or Without Straumann® Emdogain November 2012 October 2014
NCT04639661 Terminated Predictors of Periodontal Outcomes Post-sanative Therapy November 25, 2020 October 20, 2021
NCT04145557 Unknown status N/A 980nm Diode Laser in the Treatment of Periodontal Disease in Cardiac Patients August 12, 2019 May 28, 2020
NCT04477070 Unknown status N/A The Effects of Subgingival Air-polishing, as an Adjunct to Non-surgical Periodontal Treatment on Periodontal Parameters and Patient Satisfaction in Patients With Periodontitis July 21, 2020 October 21, 2023
NCT04938089 Unknown status Effect of Periodontal Maintenance Therapy on Tooth Loss in Regular and Irregular Compliant Smokers and Non-Smokers: A Cohort Retrospective Analysis With a Follow-up Up to 40 Years May 2022 July 2022
NCT04851847 Unknown status N/A A Clinical Trial to Evaluate the Safety and Effectiveness of Resorbable Collagen Membrane - MatrixflexTM June 10, 2021 August 1, 2022
NCT04477551 Unknown status N/A The Effects of Diode Laser as an Adjunct to Non-surgical Periodontal Treatment on Periodontal Status in Patients With Stage III-IV Periodontitis July 28, 2020 October 28, 2023
NCT04223076 Unknown status Phase 4 Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery March 20, 2019 December 30, 2020
NCT04237662 Unknown status N/A Enamel Matrix Derivatives & Periodontal Therapy in Diabetic Patients January 1, 2021 December 31, 2023
NCT04251858 Unknown status N/A Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes March 30, 2019 December 30, 2022
NCT04640506 Unknown status Accuracy of Assessing the Gingival Biotype in Upper Anterior in Adult Patients, Using Different Methods. November 1, 2020 August 2021
NCT04722094 Unknown status Prevalence of Periodontitis in Patients With Plaque Psoriasis. A Cross-sectional Study January 25, 2021 August 25, 2021
NCT04532255 Unknown status Periodontal Health Knowledge Among Patients With Fixed Orthodontic Appliance October 2020 August 2021
NCT04274855 Unknown status Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior February 5, 2020 December 30, 2021
NCT03241277 Unknown status N/A Nonsurgical Periodontal Treatment in Patients With Social Phobia October 5, 2017 October 5, 2019
NCT04330469 Unknown status N/A Periodontal Therapy and Oral-gut-hepatic Axis Cirrhosis: a Randomized Controlled Trial March 1, 2020 December 30, 2022
NCT03557814 Unknown status N/A LED Light As An Adjunct Treatment Modality of Periodontal Diseases September 1, 2017 August 31, 2018
NCT03557827 Unknown status Phase 3 Mechanism of Indocyanine Green-based Photodynamic Therapy for Treating Periodontitis March 1, 2018 December 31, 2019
NCT03588507 Unknown status N/A Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects September 1, 2018 November 1, 2019
NCT05232331 Unknown status N/A Intake of Vegetables Rich in Nitrate and Its Effect on the Oral Microbiota of Patients With Periodontitis June 23, 2021 November 30, 2022
NCT03102086 Unknown status The Association Between Nephrolithiasis and Periodontal Status May 11, 2017 January 2019
NCT04341636 Unknown status Phase 4 A Comparison of the Accurate Diagnosis of the Horizontal & Vertical Bitewing Images April 2020 February 2021
NCT03553888 Unknown status Hidradenitis Suppurativa and Periodontal Diseases May 7, 2018 May 7, 2020
NCT05260814 Unknown status N/A Comparison of Two Oral Hygiene Routines on the Glycemic Control for Type 2 Diabetes Patients With Chronic Periodontitis March 2022 June 2023
NCT05188924 Unknown status Phase 4 Efficacy and Safety of DKF-306 in Patients With Periodontal Diseases May 22, 2020 December 2022
NCT03513263 Unknown status N/A Effect of Periodontal Care on Rhematoid Arthritis in Uganda September 1, 2017 December 31, 2019
NCT04649645 Unknown status N/A Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems February 28, 2021 April 28, 2023
NCT03703648 Unknown status Post-radiation Dental Disease Amongst Head and Neck Cancer Patients December 1, 2018 May 31, 2023
NCT03510702 Unknown status SCREENING OF EPIGENETIC BIOMARKERS (miRNAs) IN THE GINGIVAL SULCUS September 15, 2017 July 2019
NCT03232788 Unknown status N/A Use of Scaffolds for Treatment of Gingival Recession Associated With Interproximal Tissue Deficiency April 1, 2017 December 2019
NCT03727035 Unknown status Quantification of CD163 Inflammatory Biomarker in Chronic Periodontitis and Diabetic Subjects February 10, 2018 December 15, 2019
NCT01405365 Unknown status N/A The Impact of Obesity on Nonsurgical Periodontal Therapy August 2009 December 2012
NCT04567030 Unknown status N/A Using Artificial Intelligence-platform on Plaque Control and Periodontal Treatment Outcome in Patients With Periodontal Disease-Preliminary Results November 16, 2019 December 31, 2021
NCT05153798 Unknown status Evaluation of PerioMonitor for Detection of Oral Inflammatory Load (OIL) in Human Subjects November 29, 2021 January 31, 2022
NCT04793048 Unknown status N/A A Randomized, Double-blind, Controlled Study to Evaluate the Safety and Feasibility of a Intraoral Electrotherapy Device March 22, 2021 November 30, 2021
NCT05341245 Unknown status N/A Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects May 1, 2022 June 1, 2023
NCT00763165 Unknown status Phase 3 Periodontal Disease and Cardiovascular Disease November 2000 December 2009
NCT04788979 Unknown status Phase 1/Phase 2 The Adjunctive Use of Melatonin Therapy in the Treatment of Obese Periodontitis Patients (Clinical and Immunological Study). April 1, 2021 February 2022
NCT05068778 Unknown status Development of an AI App to Improve Compliance in Periodontal Maintenance Patients September 10, 2021 June 1, 2023
NCT03814434 Unknown status N/A Surgical Treatment of Periimplantitis in Patients With Risk Factors May 28, 2018 January 28, 2020
NCT02987634 Unknown status Phase 4 Evaluation and Comparison of Efficacy of PeriActive Mouthwash to Chlorhexidine 0.12% Mouth Rinse December 2018 February 2020
NCT04946617 Unknown status Chlorhexidine and Essential Oil Mouthwashes on Human Beta-Defensin 2 (hbD2) and Kathelicidin (LL-37) Saliva Levels July 20, 2021 December 20, 2021
NCT03855345 Unknown status Phase 2 Antimicrobial Photodynamic Therapy Mediated by PapaMBlue® on Chronic Periodontal Disease March 15, 2019 April 15, 2020
NCT00133926 Unknown status Phase 2 Prevention of Pre-Term Birth by Treatment of Periodontal Disease March 2005 June 2008
NCT04051255 Unknown status N/A Influence of Smoking on Clinical, Microbiological and Immunologic Parameters in Patients With Aggressive Periodontitis. March 1, 2017 March 1, 2020
NCT02960152 Unknown status Periodontal Impact of Eating Disorders (the PERIOED Study) October 2014 January 2018
NCT03351530 Unknown status Development of a Molecular Diagnosing Platform for Monitoring Oral Hygiene in Diabetic Patients May 18, 2017 February 9, 2019
NCT04618068 Unknown status Prevalence of Periodontal Diseases Among Obese Egyptian Patients October 28, 2020 October 2021
NCT04127474 Unknown status Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease October 14, 2019 November 20, 2021
NCT04127487 Unknown status Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects October 1, 2019 December 1, 2020
NCT02523651 Unknown status Phase 1/Phase 2 Periodontal Regeneration of Chronic Periodontal Disease Patients Receiving Stem Cells Injection Therapy December 2014 December 2016
NCT04769622 Unknown status Influence of Environmental Factors on the Efficacy of Non-surgical Periodontal Treatment. A Pre-post Quasi-experimental Study February 16, 2021 November 25, 2021
NCT04023500 Unknown status N/A Supporting Oral Self-care of Patients With Periodontitis Through Motivational Interview May 1, 2014 August 30, 2019
NCT05435378 Unknown status Early Phase 1 Effect of Adjunctive Use of Vitamin B3 and B9 on Myeloperoxidase Level in the GCF of Patients With Stage I and II Periodontitis July 1, 2022 December 1, 2022
NCT03124004 Unknown status Evaluation of the Intra- and Post- Operative Bleeding After Periodontal Debridement in Direct Anticoagulant Patients August 15, 2016 November 15, 2018
NCT05403164 Unknown status Epithelial Mesenchymal Transition and Periodontitis July 12, 2021 August 30, 2022
NCT04399135 Unknown status N/A Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket February 25, 2020 June 20, 2022
NCT02737176 Unknown status N/A Tobacco Cessation Intervention Study for Oral Diseases April 2016 December 2018
NCT04771949 Unknown status Prevalence and Environmental Risk Indicators for Periodontitis. A Cross-sectional Study February 20, 2021 November 29, 2021
NCT04580355 Unknown status Phase 4 Impact of Non-surgical Periodontal Therapy on Oral and Gut Microbiome July 2021 October 2022
NCT03917030 Withdrawn N/A Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade II Furcation Defects October 15, 2019 April 15, 2027
NCT04017429 Withdrawn N/A Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST) October 15, 2019 June 15, 2027
NCT04670133 Withdrawn N/A Inulin Supplementation During Sanative Therapy to Further Improve Periodontal Healing January 1, 2024 December 31, 2026
NCT03042117 Withdrawn Connecting Periodontal and Coronary Artery Disease Via the Inflammatory State of the Body October 18, 2016 July 13, 2017
MeSH unique ID (MeSH (Medical Subject Headings))
D010510