Lyme disease
Information
- Disease name
- Lyme disease
- Disease ID
- DOID:11729
- Description
- "A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system." [url:http\://www.cdc.gov/lyme/transmission/index.html]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05634811 | Active, not recruiting | Phase 3 | Safety Study of a Vaccine to Help Protect Against Lyme Disease in Healthy Children | December 12, 2022 | June 6, 2025 |
| NCT05477524 | Active, not recruiting | Phase 3 | An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15) | August 4, 2022 | December 26, 2025 |
| NCT05975099 | Active, not recruiting | Phase 1/Phase 2 | A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age | July 26, 2023 | March 12, 2026 |
| NCT00001101 | Completed | Phase 3 | A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seropositive Chronic Lyme Disease | March 2001 | |
| NCT00037479 | Completed | Phase 2 | Brain Imaging and Retreatment Study of Persistent Lyme Disease | December 1999 | |
| NCT00594997 | Completed | N/A | A School-Based Intervention to Reduce Lyme Disease | April 2004 | August 2016 |
| NCT01143558 | Completed | Early Phase 1 | Searching for Persistence of Infection in Lyme Disease | November 4, 2010 | December 30, 2014 |
| NCT01207739 | Completed | Phase 4 | Persistent Lyme Empiric Antibiotic Study Europe | September 2010 | October 2014 |
| NCT01243008 | Completed | Phase 1/Phase 2 | Safety, Skin and Plasma Concentration of Azithromycin Dermal Formulation | April 2010 | November 2010 |
| NCT00000432 | Completed | Phase 3 | Lyme Disease Prevention Program | April 1997 | March 2001 |
| NCT01368341 | Completed | Phase 4 | Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice | June 2011 | December 2014 |
| NCT00000937 | Completed | Phase 3 | Study and Treatment of Post Lyme Disease (STOP-LD) | November 2005 | |
| NCT00000938 | Completed | Phase 3 | A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seronegative Chronic Lyme Disease | November 2005 | |
| NCT02446626 | Completed | N/A | Xenodiagnosis After Antibiotic Treatment for Lyme Disease | July 24, 2015 | May 4, 2022 |
| NCT03371563 | Completed | Erythema Migrans in Elderly | January 1, 2006 | December 31, 2018 | |
| NCT03505879 | Completed | Next Generation Sequencing Detection of Lyme Disease | July 24, 2018 | May 31, 2020 | |
| NCT03798704 | Completed | Comparison of IFA and LIAISON® for Diagnosis of Early Disseminated Lyme Borreliosis in Children, Younger Than 18 Years | January 29, 2019 | December 31, 2020 | |
| NCT03958058 | Completed | Tick-borne Encephalitis and Possible Borrelial Serology | January 1, 2007 | December 31, 2013 | |
| NCT04422314 | Completed | ImmuneSense Lyme Study | July 9, 2020 | October 30, 2021 | |
| NCT04653558 | Completed | Clinical Manifestations and Long-Term Outcome in Early Lyme Neuroborreliosis | January 1, 2008 | June 30, 2020 | |
| NCT04863287 | Completed | Phase 1 | First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People | February 11, 2021 | August 16, 2022 |
| NCT04867473 | Completed | N/A | Feasibility of Teleyoga for Treatment of Lyme Disease | October 1, 2021 | December 4, 2022 |
| NCT05041595 | Enrolling by invitation | Lyme Disease Diagnostic Assay - Collection of Whole Blood | May 3, 2021 | December 31, 2024 | |
| NCT01793168 | Recruiting | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | July 2010 | December 2100 | |
| NCT04402086 | Recruiting | Rheumatology Patient Registry and Biorepository | August 4, 2020 | June 1, 2030 | |
| NCT00001539 | Recruiting | A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations | June 13, 1996 | ||
| NCT06026969 | Recruiting | Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure | July 1, 2023 | June 2025 | |
| NCT00028080 | Recruiting | Evaluation, Treatment, and Follow-up of Patients With Lyme Disease | January 16, 2002 | ||
| NCT06045416 | Recruiting | Borrelia B-cell Diagnostics | April 2, 2024 | November 1, 2028 | |
| NCT06397794 | Recruiting | Navigating Pregnancy and Parenthood With Lyme Disease | March 20, 2024 | June 1, 2025 | |
| NCT05036707 | Recruiting | Phase 1/Phase 2 | Human Immune Response to Ixodes Scapularis Tick Bites | February 28, 2022 | June 30, 2024 |
| NCT04038346 | Recruiting | Phase 3 | Symptomatic Management of Lyme Arthritis | October 1, 2019 | December 31, 2028 |
| NCT03418441 | Recruiting | Central Nervous System Infections in Denmark | January 1, 2015 | January 1, 2030 | |
| NCT05678478 | Recruiting | Perceptions,Social Representations and Experience of Lyme Borreliosis and Ticks in Adolescents Likely to be Infected and Their Parents | February 1, 2023 | February 2025 | |
| NCT03500770 | Suspended | N/A | Lyme Disease Patients With Memory Problems | February 20, 2019 | December 31, 2020 |
| NCT03201042 | Terminated | Lyme Test Indication Combinations (LyTIC) Study | June 8, 2017 | November 30, 2018 | |
| NCT02741609 | Terminated | N/A | A Multicenter Study to Evaluate a Borrelia Diagnostic Test in Subjects With Early Stage or Late Stage Lyme Disease | April 2016 | January 2018 |
| NCT03084614 | Terminated | CD8 Reactivity to Microorganisms in Blood and Breast Milk | March 28, 2017 | November 8, 2019 | |
| NCT04577053 | Terminated | N/A | PEMF Therapy to Treat Lingering Symptoms of Lyme Disease After Treatment With Antibiotics | October 7, 2020 | September 28, 2021 |
| NCT00958139 | Terminated | Phase 3 | Passive Prophylaxis of Lyme Disease Using Permethrin Treated Clothes | June 2008 | October 2008 |
| NCT03581279 | Terminated | N/A | Detection of Borrelia Bacteria in Early Stage Lyme Borreliosis Using the T2Lyme Panel | May 8, 2018 | October 31, 2019 |
| NCT03501407 | Unknown status | Understanding Tick-borne Diseases | June 1, 2018 | June 2020 | |
| NCT03963635 | Unknown status | Novel Diagnostics for Early Lyme Disease | May 1, 2019 | December 31, 2020 | |
| NCT03981874 | Unknown status | N/A | Peripheral Facial Paralysis Sequelae in Lyme Disease Among Children | May 29, 2019 | July 29, 2019 |
| NCT04148222 | Unknown status | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Lyme Disease | March 2, 2020 | July 2023 | |
| NCT04719962 | Unknown status | N/A | Direct Diagnosis of Disseminated Lyme Borreliosis. | July 7, 2021 | July 7, 2022 |
| NCT04835792 | Unknown status | Biomarker Study of Previously Treated Lyme Disease Volunteers in Comparison to Healthy Volunteers | March 21, 2021 | September 30, 2021 | |
| NCT05312619 | Unknown status | The Burden of Lyme Disease (BOLD) in a Pandemic - Insights From an Online Cross-sectional and Prospective Cohort Survey | July 7, 2021 | November 7, 2023 | |
| NCT04318925 | Withdrawn | Evaluation and Follow-up of People With Tick-borne Diseases | November 13, 2023 | November 13, 2023 |
- Disase is a (Disease Ontology)
- DOID:0050338
- Cross Reference ID (Disease Ontology)
- GARD:12073
- Cross Reference ID (Disease Ontology)
- ICD10CM:A69.2
- Cross Reference ID (Disease Ontology)
- ICD9CM:088.81
- Cross Reference ID (Disease Ontology)
- MESH:D008193
- Cross Reference ID (Disease Ontology)
- MESH:D020852
- Cross Reference ID (Disease Ontology)
- NCI:C45161
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154376000
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:715507005
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0024198
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0752235
- Exact Synonym (Disease Ontology)
- Bannwarth syndrome
- Exact Synonym (Disease Ontology)
- Bannworth's syndrome
- Exact Synonym (Disease Ontology)
- Lyme borreliosis
- Exact Synonym (Disease Ontology)
- lyme neuroborreliosis
- Exact Synonym (Disease Ontology)
- neuroborreliosis
- Exact Synonym (Disease Ontology)
- Neurological Lyme disease
- OrphaNumber from OrphaNet (Orphanet)
- 91546
- ICD10 preferred id (Insert disease from ICD10)
- D0000352
- ICD10 class code (Insert disease from ICD10)
- A69.2
- MeSH unique ID (MeSH (Medical Subject Headings))
- D008193