schizophrenia
Information
- Disease name
- schizophrenia
- Disease ID
- DOID:5419
- Description
- "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." [url:http\://en.wikipedia.org/wiki/Schizophrenia]
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| RNY1P9 | 22 | 20,475,203 | 20,475,311 | 22 |
| SLC9A3P2 | 22 | 20,652,730 | 20,654,750 | 22 |
| KLHL22 | 22 | 20,441,519 | 20,495,795 | 22 |
| USP41P | 22 | 20,363,621 | 20,377,251 | 22 |
| RN7SL812P | 22 | 20,481,935 | 20,482,213 | 22 |
| RNU6-225P | 22 | 20,416,797 | 20,416,899 | 22 |
| MED15 | 22 | 20,507,610 | 20,587,619 | 22 |
| ZNF74 | 22 | 20,394,151 | 20,408,455 | 22 |
| SMPD4P1 | 22 | 20,602,595 | 20,626,134 | 22 |
| KRT18P5 | 22 | 20,482,815 | 20,484,105 | 22 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03437668 | Active, not recruiting | Phase 2/Phase 3 | Adjunctive Withania Somnifera (Ashwagandha) for Persistent Symptoms in People With Schizophrenia | December 1, 2018 | December 31, 2024 |
| NCT05032963 | Active, not recruiting | N/A | Neurocognition After Perturbed Sleep | September 21, 2021 | May 2024 |
| NCT05200962 | Active, not recruiting | Phase 1 | Electrical Brain Stimulation for Cognitive Impairment in Schizophrenia: a tDCS-fMRI Study | February 1, 2022 | August 1, 2024 |
| NCT05623228 | Active, not recruiting | Phase 2 | The Effectiveness and Efficacy of the Combination of the Integrated Psychological Therapy and Metacognitive Training. | November 1, 2022 | December 20, 2024 |
| NCT05746494 | Active, not recruiting | N/A | The Efficacy of Neural Stimulation in Individuals With Schizophrenia | November 21, 2022 | May 2025 |
| NCT03121586 | Active, not recruiting | Phase 3 | Extension Study of Pimavanserin for the Adjunctive Treatment of Schizophrenia | January 2017 | February 2025 |
| NCT05065489 | Active, not recruiting | Resting State Electroencephalogram for Psychotic Disorders | September 1, 2021 | December 1, 2023 | |
| NCT03238326 | Active, not recruiting | Phase 3 | Safety and Tolerability of Open-Label Flexible-dose Brexpiprazole as Maintenance Treatment in Adolescents With Schizophrenia | August 23, 2017 | May 2025 |
| NCT04531982 | Active, not recruiting | Phase 3 | Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia | August 5, 2020 | January 2024 |
| NCT03246932 | Active, not recruiting | N/A | Peer-led Psycho-education for Schizophrenia | December 1, 2020 | June 30, 2024 |
| NCT04714970 | Active, not recruiting | N/A | rTMS on Appetite and Cognitive Function in Schizophrenia | April 20, 2021 | December 1, 2022 |
| NCT01409109 | Active, not recruiting | Database Registry for Neural Network Biomarkers in Psychosis | March 2010 | May 2025 | |
| NCT00512070 | Active, not recruiting | N/A | Melatonin Metabolism Abnormality in Patients With Schizophrenia or Schizoaffective Disorder Treated With Olanzapine | July 2007 | December 2025 |
| NCT04860830 | Active, not recruiting | Phase 3 | CONNEX-3: A Study to Test Whether Iclepertin Improves Learning and Memory in People With Schizophrenia | June 18, 2021 | November 22, 2024 |
| NCT05182476 | Active, not recruiting | Phase 2 | Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia | December 7, 2021 | March 2025 |
| NCT03829280 | Active, not recruiting | N/A | Cognitive Adaption Training-Effectiveness in Real-world Settings and Mechanism of Action (CAT-EM) | April 4, 2019 | April 2025 |
| NCT01545999 | Active, not recruiting | N/A | Paired Associative Stimulation in the Dorsolateral Prefrontal Cortex in Patients With Schizophrenia | March 2012 | December 2024 |
| NCT02088060 | Active, not recruiting | Phase 2 | A Four-week Clinical Trial Investigating Efficacy and Safety of Cannabidiol as a Treatment for Acutely Ill Schizophrenic Patients | December 8, 2015 | June 30, 2025 |
| NCT04959032 | Active, not recruiting | Phase 3 | Lumateperone for the Prevention of Relapse in Patients With Schizophrenia | July 8, 2021 | September 2024 |
| NCT03451630 | Active, not recruiting | N/A | PCORI Integrated Care (IC) Models for Patient-Centered Outcomes | April 23, 2018 | August 31, 2024 |
| NCT04820309 | Active, not recruiting | Phase 3 | An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5) | June 2, 2021 | June 2024 |
| NCT03245437 | Active, not recruiting | Phase 4 | Target Engagement and Response to Oxytocin | January 4, 2018 | July 31, 2024 |
| NCT04846868 | Active, not recruiting | Phase 3 | Clinical Trial of Iclepertin Effect on Cognition and Functional Capacity in Schizophrenia (CONNEX-1) | June 16, 2021 | October 11, 2024 |
| NCT05571228 | Active, not recruiting | N/A | Be Outspoken and Overcome Stigmatizing Thoughts (BOOST) Group for Early Psychosis | October 1, 2020 | December 31, 2024 |
| NCT05368558 | Active, not recruiting | Phase 3 | Study to Assess Adverse Events and Change in Disease Activity of Oral Cariprazine Capsules in Adult Participants With Schizophrenia | August 18, 2022 | August 11, 2034 |
| NCT06370793 | Active, not recruiting | Ningbo Severe Mental Disorders Cohort | July 1, 2018 | December 31, 2026 | |
| NCT00179465 | Active, not recruiting | Phase 3 | Treating Schizophrenia by Correcting Abnormal Brain Development | November 2003 | September 2024 |
| NCT02102113 | Active, not recruiting | Early Phase 1 | Probing the Cannabinoid System in Individuals With a Family History of Psychosis | January 2014 | December 2024 |
| NCT04846881 | Active, not recruiting | Phase 3 | Clinical Trial of Iclepertin Effect on Cognition and Functional Capacity in Schizophrenia (CONNEX-2) | June 7, 2021 | November 13, 2024 |
| NCT02357797 | Active, not recruiting | Phase 4 | Adjunctive Vortioxetine in Schizophrenia | February 2016 | June 1, 2024 |
| NCT06063525 | Active, not recruiting | Biological Implications of the Overlapping Phenomenon Between Childhood Schizophrenia and Autism Spectrum Disorders-Heterogeneity Approach Rather Than Diagnostic Boundary | February 2, 2015 | December 31, 2024 | |
| NCT01941251 | Active, not recruiting | N/A | Navigated αTMS in Treatment-resistant Schizophrenia | March 2013 | December 2025 |
| NCT03788811 | Active, not recruiting | ERG Components in Schizophrenia and Bipolar Disorder Type I | July 5, 2018 | December 31, 2024 | |
| NCT05693935 | Active, not recruiting | Phase 3 | A Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label, Long-Term Safety Phase to Evaluate the Efficacy and Safety of TV-44749 in Adults With Schizophrenia | January 24, 2023 | January 13, 2025 |
| NCT05086133 | Active, not recruiting | N/A | cTBS on First-episode Drug Naive Patients With Schizophrenia | November 20, 2021 | June 1, 2023 |
| NCT03034356 | Active, not recruiting | Phase 1/Phase 2 | Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia | September 1, 2018 | June 30, 2024 |
| NCT03481049 | Active, not recruiting | N/A | Individualizing Incentives for Alcohol in the Severely Mentally Ill | May 5, 2018 | August 31, 2024 |
| NCT05658510 | Active, not recruiting | Phase 3 | Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III) | November 21, 2022 | March 30, 2025 |
| NCT00587561 | Active, not recruiting | N/A | Efficacy of Social Cognition Training in Schizophrenia | January 2008 | December 2023 |
| NCT05660070 | Active, not recruiting | N/A | Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness | July 1, 2022 | December 31, 2024 |
| NCT03896438 | Active, not recruiting | N/A | Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 2 | July 1, 2019 | April 2024 |
| NCT01383915 | Active, not recruiting | Clinical Risk State for Bipolar Disorder in Adolescents | September 2009 | December 31, 2023 | |
| NCT04624243 | Active, not recruiting | Phase 2 | Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008) | December 15, 2020 | July 15, 2024 |
| NCT00218218 | Completed | Phase 2 | Effects of Transdermal Nicotine on Smoking, Craving and Withdrawal in People With Schizophrenia | June 2002 | February 2005 |
| NCT04010305 | Completed | Phase 1 | Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia | May 22, 2019 | July 31, 2019 |
| NCT02734927 | Completed | N/A | Motivation and Executive Control in Schizophrenia | November 2012 | April 24, 2018 |
| NCT01373866 | Completed | N/A | Multimodal MRI-guided rTMS to Treat Refractory Hallucinations | November 15, 2010 | February 11, 2022 |
| NCT00892125 | Completed | Phase 1 | A Study of the Effect of Carbamazepine on the Pharmacokinetics of Paliperidone Extended Release (ER) in Patients With Schizophrenia or Bipolar I Disorder | September 2006 | March 2007 |
| NCT00204061 | Completed | Phase 4 | Early Pharmacological and Psychological Intervention for Late Prodromal States of Psychosis | January 2001 | June 2005 |
| NCT00253110 | Completed | Phase 4 | A Comparison of Risperidone With Haloperidol in Patients With Schizophrenia and Schizoaffective Disorder | May 1996 | September 1998 |
| NCT01399437 | Completed | Brain Functions Underlying Visuospatial Attention Deficits in Schizophrenia | July 3, 2011 | December 24, 2014 | |
| NCT00145496 | Completed | Phase 3 | Efficacy and Safety of Asenapine Compared With Olanzapine in Patients With Persistent Negative Symptoms of Schizophrenia (A7501013)(COMPLETED)(P05771) | December 2004 | December 2008 |
| NCT00036088 | Completed | Phase 4 | Olanzapine Versus An Active Comparator in the Treatment of Schizophrenia | August 2001 | July 2002 |
| NCT02819349 | Completed | N/A | Texting for Relapse Prevention | March 12, 2018 | April 9, 2019 |
| NCT02050854 | Completed | Open-Label Observational Pilot Study to Evaluate the Pharmacokinetics of Aripiprazole in Subjects With Bipolar 1 Disorder or Schizophrenia | December 2013 | January 2014 | |
| NCT00159133 | Completed | Phase 4 | Prodrome-Based Early Intervention With Antipsychotics vs. Benzodiazepines in First-Episode Schizophrenia | November 2001 | June 2006 |
| NCT01516424 | Completed | Phase 3 | Efficiency Study to Investigate Blonanserin in Treatment of Schizophrenia When Compared With Risperidone | February 2012 | February 2013 |
| NCT00495118 | Completed | Phase 3 | A Long-term Safety Study for Long-acting Injectable Risperidone in Schizophrenia or Schizoaffective Disorder Patients. | October 2001 | March 2005 |
| NCT00936351 | Completed | N/A | Mindfulness Meditation as a Rehabilitation Strategy for Persons With Schizophrenia | December 2007 | December 2010 |
| NCT00538629 | Completed | Non Interventional Study In Bipolar Disorder And Schizophrenia With Zeldox | October 16, 2007 | April 30, 2008 | |
| NCT02170051 | Completed | N/A | Improving Negative Symptoms of Psychosis In Real-world Environments | July 1, 2014 | September 3, 2018 |
| NCT00864045 | Completed | Phase 3 | Sertindole in Asian Patients With Schizophrenia | March 2007 | May 2008 |
| NCT04521868 | Completed | Phase 2 | A 6-month Study to Evaluate Sulforaphane Effects in Schizophrenia Patients | August 31, 2020 | August 12, 2022 |
| NCT04856657 | Completed | Targeting Individual Alpha Frequencies to Enhance Perceptual Timing | November 1, 2021 | February 9, 2023 | |
| NCT00791401 | Completed | Phase 1 | A Study of the Pharmacokinetics of ER OROS Paliperidone in Volunteers With Normal or Impaired Renal Function | April 2004 | February 2005 |
| NCT00528359 | Completed | β-Cell Function in Schizophrenic Subjects on Atypical Antipsychotic drugS | October 2005 | February 2007 | |
| NCT03075657 | Completed | Phase 4 | Study of add-on Ramelteon Therapy on Sleep and Circadian Rhythm Disruption in Patients With Schizophrenia | May 1, 2017 | August 31, 2018 |
| NCT00797927 | Completed | Phase 4 | Quetiapine Related Neurochemical Changes as Measured by Magnetic Resonance Spectroscopy in Schizophrenia | January 2007 | April 2009 |
| NCT00246272 | Completed | Phase 3 | An Open-label Study Evaluating the Maintenance of Clinical Effect in Adult Schizophrenia Patients Switched From Risperidone Tablets to an Equivalent Dose of a Rapidly-dissolving Tablet Formulation of Risperdone | October 2004 | May 2006 |
| NCT00057707 | Completed | Phase 1 | Effects of Modafinil on Brain Function in Patients With Schizophrenia | March 26, 2003 | June 16, 2017 |
| NCT00753051 | Completed | N/A | Treat Clozapine ( CLZ )-Resistant Schizophrenia Comparing CLZ + Haloperidol vs. CLZ + Electroconvulsive Therapy (ECT) | June 2008 | May 2012 |
| NCT02128919 | Completed | N/A | Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in Schizophrenic | April 2012 | December 2016 |
| NCT01376596 | Completed | Phase 1/Phase 2 | Group Cognitive-behavioral Intervention for Social Anxiety in Schizophrenia | August 2011 | January 2013 |
| NCT00483964 | Completed | Phase 2 | A Safety and Efficacy Study of Bacopa Monnieri and Nardostachys Jatamansi to Treat Schizophrenia | September 2005 | September 2007 |
| NCT00156091 | Completed | Phase 3 | Long-Term Efficacy and Safety of Asenapine Using Olanzapine as a Positive Control (41512)(COMPLETED)(P05784) | April 2005 | June 2007 |
| NCT02202213 | Completed | Phase 1 | Safety and Tolerability Study of Lu AF11167 After Repeated Dosing in Patients With Schizophrenia | October 2013 | |
| NCT02137993 | Completed | Phase 4 | Efficacy and Safety of A-prexa Compared to Zyprexa in Patients With Schizophrenia | March 2012 | May 2013 |
| NCT03695614 | Completed | N/A | Cognitive Remediation Therapy for Participants With Late-Life Schizophrenia | October 24, 2018 | March 12, 2020 |
| NCT02570594 | Completed | N/A | Autobiographical Memory Organization in Schizophrenia | January 2014 | June 2017 |
| NCT00073320 | Completed | Phase 3 | Intramuscular Injections of Paliperidone Palmitate in the Arm or Buttock of Subjects With Schizophrenia | August 2003 | May 2004 |
| NCT00768326 | Completed | Phase 2 | Efficacy of Lu 31-130 in Patients With Schizophrenia | March 2007 | November 2009 |
| NCT01043250 | Completed | Effects of Atypical Antipsychotics on Appetite and Eating Behavior of Schizophrenia Patients | May 2009 | December 2010 | |
| NCT01243034 | Completed | Waist Circumference Measurements in Schizophrenic Patients | August 1, 2010 | July 31, 2011 | |
| NCT00006418 | Completed | Molecular Genetics of Schizophrenia | September 2003 | August 2007 | |
| NCT05321602 | Completed | Phase 1 | Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder | September 8, 2021 | October 23, 2022 |
| NCT02832401 | Completed | N/A | The Impact of Caffeine on Cognition in Schizophrenia | September 2, 2016 | August 2, 2019 |
| NCT02220504 | Completed | N/A | 3-year Follow-up of Clinical Outcome After Antipsychotic Treatment Discontinuation in Psychosis Individuals | July 2004 | July 2014 |
| NCT02715349 | Completed | N/A | Psychoeducation for Vietnamese Families With a Patient With Schizophrenia | September 2014 | July 2015 |
| NCT01394471 | Completed | Phase 1 | Oxytocin Treatment of Social Cognitive and Functional Deficits in Schizophrenia | July 2011 | January 2015 |
| NCT00100165 | Completed | Phase 2 | Phase 2 Trial of a Nicotinic Agonist in Schizophrenia | January 2005 | July 2007 |
| NCT00286299 | Completed | N/A | Treatment Effects From Aerobic Endurance Training and Maximal Strength Training in Patients Suffering From Schizophrenia | October 2005 | July 2008 |
| NCT02769936 | Completed | Phase 1 | Glutamate, Learning, and Working Memory | November 2013 | December 2015 |
| NCT00952393 | Completed | Phase 1 | Nicotinic Receptors and Schizophrenia | January 2010 | October 2014 |
| NCT02634346 | Completed | Phase 3 | A Study of ALKS 3831 in Adults With Acute Exacerbation of Schizophrenia (the ENLIGHTEN-1 Study) | December 2015 | June 7, 2017 |
| NCT02391649 | Completed | N/A | Problem-solving-based Bibliotherapy Program for Family Caregivers | March 1, 2014 | August 30, 2020 |
| NCT03699501 | Completed | Psychometric Validation of an Oral Health-related Scale for Quality of Life and Coping in People With Schizophrenia | April 15, 2019 | July 9, 2021 | |
| NCT00137267 | Completed | N/A | A Brief Community Linkage Intervention for Dually Diagnosed Individuals | June 2005 | June 2009 |
| NCT05716802 | Completed | N/A | Dance/Movement Therapy for Bone Mineral Density in Schizophrenia | July 7, 2020 | July 12, 2022 |
| NCT01004354 | Completed | N/A | Vitamin D Supplementation in Psychiatric Illnesses | June 2009 | June 2010 |
| NCT00255515 | Completed | Phase 4 | Seroquel® Combined With Cognitive Remediation Therapy to Conventional Treatment in Patients With Schizophrenia | September 2005 | December 2007 |
| NCT00499044 | Completed | N/A | A Comparison of Two Cognitive Batteries in People With Schizophrenia | December 2007 | March 2009 |
| NCT00167362 | Completed | Phase 3 | Cognitive Enhancement Therapy for Early-Stage Schizophrenia | August 2001 | December 2016 |
| NCT00148564 | Completed | Phase 4 | Energy Homeostasis Under Treatment With Atypical Antipsychotics | March 2004 | June 2007 |
| NCT02105779 | Completed | N/A | Optimizing Cognitive Remediation Outcomes in Schizophrenia | December 2009 | July 26, 2016 |
| NCT00520923 | Completed | Phase 2 | A Study for Patients With Schizophrenia | September 2007 | October 2008 |
| NCT01213836 | Completed | Phase 4 | Compare the Effect on Cognitive Functioning of Two Formulations of Seroquel, Seroquel XR and IR in Patients With Stable Schizophrenia | November 2010 | August 2011 |
| NCT00237796 | Completed | N/A | Functional Rehabilitation of Older Patients With Schizophrenia | February 2005 | January 2009 |
| NCT01731119 | Completed | Phase 2 | Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents | December 2012 | August 2014 |
| NCT01164059 | Completed | Phase 4 | Clinical Effectiveness of Newer Antipsychotics in Comparison With Conventional Antipsychotics in Schizophrenia | February 2010 | March 2014 |
| NCT00810355 | Completed | N/A | Cognitive Behavior Therapy and Work Outcome | October 1, 2009 | August 6, 2015 |
| NCT00809770 | Completed | N/A | Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill | April 2008 | August 2013 |
| NCT01649557 | Completed | Phase 2 | Multicenter, Open-label, Safety and Tolerability Study | August 2009 | September 2011 |
| NCT01724476 | Completed | Phase 4 | A Trial of Folate With B12 in Patients With Schizophrenia With Residual Symptoms in Ethiopia | December 2014 | December 2017 |
| NCT00169065 | Completed | Phase 4 | Effectiveness of Clozapine Versus Olanzapine for Treatment-resistant Schizophrenia | August 1998 | June 2002 |
| NCT01078129 | Completed | N/A | Cognitive Remediation Therapy and Schizophrenia | January 2006 | December 2010 |
| NCT00237939 | Completed | Phase 3 | A Study of Aripiprazole in the Management of Patients With Schizophrenia in the General Psychiatric Practices | September 2002 | November 2006 |
| NCT00575666 | Completed | Phase 4 | Intranasal Insulin Treatment in Patients With Schizophrenia | December 2007 | September 2010 |
| NCT02131116 | Completed | N/A | Integrated Metacognitive Therapy in First Episode Psychosis | May 2014 | December 2017 |
| NCT02008773 | Completed | Phase 2 | A Double-Blind Trial of Adjunctive Valacyclovir to Improve Cognition in Early Phase Schizophrenia | March 26, 2014 | June 20, 2017 |
| NCT01143077 | Completed | Phase 3 | A Study Evaluating Lurasidone for The Treatment of Schizophrenia or Schizoaffective Disorder in Subjects Switched From Other Antipsychotic Agents | June 2010 | May 2011 |
| NCT02431702 | Completed | Phase 3 | A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform | July 8, 2015 | November 12, 2019 |
| NCT04738123 | Completed | Phase 3 | A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-3) | April 6, 2021 | December 7, 2022 |
| NCT00522613 | Completed | N/A | Recovery Group Pilot | July 2005 | December 2006 |
| NCT04481737 | Completed | N/A | Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery | February 1, 2021 | January 1, 2024 |
| NCT05402111 | Completed | Phase 1 | A Clinical Study That Will Assess How Food Moves Through the Stomach and Effects Blood Glucose Levels in Subjects With Schizophrenia Taking SEP-363856 or and Prior Antipsychotic (PA) Standard | June 13, 2022 | September 27, 2023 |
| NCT01909466 | Completed | Phase 1 | Safety and Tolerability Study of Aripiprazole IM Depot in Adult Subjects With Schizophrenia | July 2013 | April 2014 |
| NCT02019329 | Completed | Phase 1 | A Study of the Safety, Tolerability and Pharmacokientics of RO5545965 in Patients With Schizophrenia on Risperidone | January 2014 | August 2014 |
| NCT00391677 | Completed | N/A | Attention Shaping Procedures for Improving Psychosocial Skills Among Adults With Schizophrenia | January 2007 | June 2011 |
| NCT00922090 | Completed | A Non-interventional Study Evaluating the Clinical Benefit and Effectiveness of Quetiapine Fumarate Extended | July 2009 | January 2010 | |
| NCT01376076 | Completed | Phase 1 | Effects of Cariprazine on Cardiac Repolarization in Patients With Schizophrenia | June 2011 | February 2012 |
| NCT00222235 | Completed | Phase 2/Phase 3 | Adjunctive Treatment for Decreasing Symptoms of Schizophrenia | January 2000 | June 2004 |
| NCT01567943 | Completed | N/A | Contingency Management of Alcohol Abuse in the Severely Mentally ILL | March 2012 | February 2016 |
| NCT00492336 | Completed | Phase 4 | Rasagiline in the Treatment of Persistent Negative Symptoms of Schizophrenia | January 2007 | February 2012 |
| NCT00063297 | Completed | Phase 2 | Safety and Efficacy of Study Drug Versus Placebo for Negative Symptoms of Schizophrenia | May 2003 | October 2003 |
| NCT02469155 | Completed | Phase 3 | A Trial to Assess the Antipsychotic Efficacy of ITI-007 Over 6 Weeks of Treatment | June 2015 | August 2016 |
| NCT01969500 | Completed | N/A | Development of a Mobile System for Self-management of Schizophrenia (SOS) | November 2015 | February 2017 |
| NCT02593734 | Completed | Phase 4 | Integrating Psychotropic Medication Into the Care of People With Mental Disorders in a Prayer Camp in Ghana | July 2013 | July 2015 |
| NCT00505076 | Completed | Phase 2 | Treatment Study for Cognitive Deficits in Schizophrenia | July 2007 | September 2009 |
| NCT01683058 | Completed | Phase 3 | Open-label, Extension Study of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in Patients With Schizophrenia | January 2013 | February 2014 |
| NCT00759460 | Completed | Phase 3 | Study on Metabolic Parameters of Sertindole in Patients With Schizophrenia | March 2007 | April 2008 |
| NCT02905604 | Completed | N/A | Magnetic Stimulation of the Brain in Schizophrenia or Depression | September 29, 2016 | January 20, 2020 |
| NCT00018629 | Completed | Phase 2 | Cognitive - Behavioral Therapy | May 2000 | April 2005 |
| NCT01093365 | Completed | Phase 2 | Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia | March 2010 | August 2016 |
| NCT02620267 | Completed | N/A | Target Engagement of the Early Auditory Processing Network by Transcranial Direct Current Stimulation (tDCS) | December 15, 2015 | June 30, 2019 |
| NCT03975400 | Completed | N/A | Using Digital Media Advertising to Reduce the Duration of Untreated Psychosis | April 22, 2020 | May 31, 2023 |
| NCT01626885 | Completed | Phase 2/Phase 3 | A Long-Term Study of MP-214 in Patients With Receiving Multiple Drugs Schizophrenia | May 2012 | June 2014 |
| NCT01003132 | Completed | N/A | Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis | October 2009 | October 2010 |
| NCT02504151 | Completed | Phase 2 | Cannabidiol Treatment in Patients With Early Psychosis | January 28, 2016 | March 9, 2018 |
| NCT02976077 | Completed | N/A | RC2S+: Remediation of Social Cognitive Impairments | November 29, 2016 | December 30, 2021 |
| NCT01875822 | Completed | Phase 1/Phase 2 | Open-label Study of Curcumin C-3 Complex in Schizophrenia | June 2009 | May 2012 |
| NCT02520024 | Completed | N/A | Assessing the Impact of Self-directed Care, Within a Medicaid-funded Environment,on Participation and Community Living | January 2010 | March 2012 |
| NCT01028677 | Completed | N/A | Oxytocin Treatment of Schizophrenia | November 2009 | March 2011 |
| NCT03316664 | Completed | N/A | Assessment of Efficacy of a Psychological Therapy in Inpatients With a Schizophrenic Psychosis | June 1, 2018 | August 31, 2021 |
| NCT00480571 | Completed | Phase 2 | Safety and Tolerability of BL-1020 in Hospitalized Subjects With Chronic Schizophrenia or Schizo-Affective Disorder | June 2007 | December 2007 |
| NCT00095524 | Completed | Phase 3 | Effects of Aripiprazole in Overweight Patients Treated With Olanzapine for Schizophrenia or Schizoaffective Disorder | March 2004 | August 2006 |
| NCT01658150 | Completed | N/A | Evaluating Isradipine for Cognitive Enhancement in Schizophrenia and Schizoaffective Disorder | September 2012 | January 2, 2018 |
| NCT00661869 | Completed | N/A | Outcome Evaluation of Solutions for Wellness and Team Solutions Program in Patients With Severe Mental Illness | September 2006 | January 2008 |
| NCT02449746 | Completed | N/A | Study of Immunotherapy in Autoantibody Positive Psychosis | August 2015 | December 2017 |
| NCT01140620 | Completed | Phase 4 | Effects of Ketamine and Risperidone on Cognition | June 2010 | December 2010 |
| NCT01614912 | Completed | Phase 3 | Long-term Extension Study of SM-13496 (Lurasidone HCl) in Patients With Schizophrenia | August 2012 | May 2015 |
| NCT03953664 | Completed | N/A | The Effects of Three Different Modalities of Exercise in Patients With Schizophrenia | January 14, 2020 | April 1, 2021 |
| NCT00456937 | Completed | Phase 4 | Escitalopram in Schizophrenia in OCD- Open Label Study | July 2006 | September 2008 |
| NCT01685931 | Completed | Phase 4 | A Study of Paliperidone Palmitate in Patients With Schizophrenia Previously Unsuccessfully Treated by Oral Antipsychotics | November 2012 | December 2014 |
| NCT01795183 | Completed | Phase 4 | Effectiveness and Safety of Amisulpride in Chinese Patients With Schizophrenia | November 2012 | December 2013 |
| NCT04038957 | Completed | Phase 1 | A Clinical Study to Investigate the Effect of an Investigational Drug as an Added Medication to an Antipsychotic, in Adults With Schizophrenia, as Measured Positron Emission Tomography (PET) Imaging | August 7, 2019 | June 6, 2023 |
| NCT01714011 | Completed | Phase 4 | Safety and Efficacy of Aripiprazole and Ziprasidone Among Schizophrenic Patients With Metabolic Syndrome | May 2009 | September 2011 |
| NCT05953740 | Completed | Phase 1 | A Study of MK-5720 in Participants With Schizophrenia (MK-5720-001) | September 15, 2023 | February 15, 2024 |
| NCT02360228 | Completed | N/A | STimulation to Improve Auditory haLLucinations | May 2015 | February 2017 |
| NCT00223535 | Completed | N/A | Cognitive Remediation and Social Skills Training in Schizophrenia | February 2003 | March 2005 |
| NCT03172871 | Completed | Phase 3 | Aripiprazole IM Depot in the Acute Treatment of Adults With Schizophrenia | May 15, 2017 | September 30, 2019 |
| NCT00892320 | Completed | Phase 1 | A Study of the Effect of Food on the Pharmacokinetics of ER OROS Paliperidone in Healthy Japanese Volunteers | March 2004 | May 2004 |
| NCT05893862 | Completed | Phase 1 | A Study To Evaluate The Effect Of A Supratherapeutic Dose Of MK-8189 On The QTc Interval In Participants With Schizophrenia (MK-8189-019) | June 26, 2023 | February 22, 2024 |
| NCT03049813 | Completed | N/A | Virtual Reality Job Interview Training in Severe Mental Illness | June 1, 2017 | July 31, 2022 |
| NCT02335658 | Completed | Phase 3 | Long-term Study of DSP-5423P in Patients With Schizophrenia | December 2014 | May 2017 |
| NCT00533260 | Completed | A Non-interventional Naturalistic Project to Investigate the Effect of the Use of SMS Text Service on Treatment Adherence in Patients Treated With Seroquel® (Quetiapine) | July 2007 | April 2008 | |
| NCT03393026 | Completed | Phase 4 | A Study of Lurasidone HCl in Subjects With Schizophrenia | January 3, 2018 | September 17, 2019 |
| NCT01829048 | Completed | Phase 1 | A Study To Examine The Safety, Tolerability And Pharmacokinetics Of PF-02545920 In Psychiatrically Stable Subjects With Schizophrenia | March 6, 2013 | October 17, 2013 |
| NCT05342727 | Completed | Phase 1 | Transcranial Direct and Alternating Stimulation of the Prefrontal Cortex for Cognitive Improvement in Schizophrenia | April 1, 2021 | July 31, 2022 |
| NCT00308997 | Completed | Phase 2 | Transcranial Magnetic Stimulation for "Voices" | February 2006 | April 2012 |
| NCT01512290 | Completed | N/A | Theta Burst Transcranial Magnetic Stimulation as Treatment for Auditory Verbal Hallucinations | March 2012 | May 2014 |
| NCT01491412 | Completed | Non-interventional Study: Real-life Use of Atypical Antipsychotics in Acute Inpatient Management of Schizophrenia | December 2011 | May 2012 | |
| NCT05109572 | Completed | The Impact of the Covid-19 Pandemic on Schizophrenia Patients Registered With the Community Mental Health Center | March 20, 2021 | July 20, 2021 | |
| NCT01212575 | Completed | A Retrospective NIS to Evaluate the Use of Seroquel XR and IR in the Clinical Practice of Outpatients With Schizophrenia | October 2010 | February 2011 | |
| NCT00069433 | Completed | N/A | Enhancing the Outcome of Skills Training for People With Schizophrenia | April 2001 | November 2005 |
| NCT00306475 | Completed | Phase 4 | Does The Addition Of Divalproex Sodium ER To An Atypical Antipsychotic Drug (APD) Improve Cognition And Psychopathology In Outpatients With Schizophrenia (SCH) Or Schizoaffective Disorder (SAD)? | March 2006 | April 2008 |
| NCT03559426 | Completed | Phase 4 | Research Into Antipsychotic Discontinuation and Reduction Trial | March 24, 2016 | March 10, 2022 |
| NCT00523445 | Completed | Phase 3 | The Effects of Varenicline on Cognitive Function in Patients With Schizophrenia | September 2007 | July 2009 |
| NCT01026285 | Completed | InORS - International Observational Registry on Schizophrenia With Injectable Risperidone and Oral Antipsychotics | June 2009 | March 2012 | |
| NCT04418011 | Completed | N/A | Neuromodulation of Social Cognitive Circuitry in People With Schizophrenia Spectrum Disorders | November 30, 2020 | February 2, 2023 |
| NCT00154258 | Completed | Phase 2 | A Long Term Study of Clozapine in Patients With Treatment-resistant Schizophrenia | April 2001 | December 2009 |
| NCT00796471 | Completed | Phase 1 | A Pharmacokinetics and Pharmacodynamics Study Under Fasting and Fed Conditions With Paliperidone Extended-release and Immediate-release Formulations | June 2003 | August 2003 |
| NCT00334126 | Completed | Phase 3 | Evaluation of Effectiveness and Safety of Paliperidone ER (Extended-release) Compared With Quetiapine in Patients With Schizophrenia | April 2006 | September 2007 |
| NCT01149551 | Completed | CSP #572 - Genetics of Functional Disability in Schizophrenia and Bipolar Illness | February 2011 | July 2014 | |
| NCT00159770 | Completed | Phase 3 | Effect And Safety Of Ziprasidone Compared To Other Atypical Antipsychotic Drug In Schizophrenic Patients | November 2001 | September 2004 |
| NCT02663349 | Completed | N/A | Skills Training to Enhance Vocational Outcomes in Veterans With Serious Mental Illness | January 2016 | July 2019 |
| NCT03128099 | Completed | N/A | Virtual Reality Training for Social Skills in Schizophrenia | June 2016 | June 30, 2018 |
| NCT03048695 | Completed | N/A | Goal Management Training for Patients With Schizophrenia or High Risk for Schizophrenia | May 18, 2017 | December 31, 2020 |
| NCT02360813 | Completed | N/A | Cognitive Remediation Therapy Within a Secure Forensic Setting | August 2014 | January 2017 |
| NCT05262790 | Completed | The Difference of Grey Matter Volume Among the Patients of Schizophrenia | June 26, 2013 | January 1, 2017 | |
| NCT02342210 | Completed | N/A | Mindfulness Group-based Intervention for Early Psychosis: A Pilot Study | May 2015 | April 2016 |
| NCT00350805 | Completed | Measuring Time Windows in Patients With Schizophrenia and Healthy Controls | September 2005 | December 2012 | |
| NCT02203838 | Completed | Phase 3 | Long Term Study of RBP 7000 in the Treatment of Subjects With Schizophrenia | June 2014 | September 2016 |
| NCT01499563 | Completed | Phase 2 | Study of a Novel Antipsychotic ITI-007 in Schizophrenia | December 2011 | November 2013 |
| NCT01412060 | Completed | Phase 3 | A Study of Cariprazine in the Prevention of Relapse of Symptoms in Participants With Schizophrenia | September 27, 2011 | September 3, 2014 |
| NCT04312503 | Completed | Observational Study on the Effect of Switch to Lurasidone in Subjects With Schizophrenia" | July 13, 2020 | October 31, 2022 | |
| NCT00236548 | Completed | Phase 3 | Evaluation of the Usefulness to Doctors of the Risperdal Consta Treatment Guidebook Over a Three-month Period During Which Adult Patients With Schizophrenia or Schizoaffective Disorder Are Switching From Daily Doses or Risperidone Tablets to Long-acting Risperidone by Injection | January 2003 | |
| NCT03713658 | Completed | Phase 4 | A Study to Evaluate the Ability of Conducting a Study of Oral Risperidone Followed by Paliperidone Palmitate in Rwandan Healthcare Facilities | October 18, 2018 | December 2, 2019 |
| NCT04076371 | Completed | N/A | The Treatment Efficacy of Combination Atypical Antipsychotics With Sertraline in Patients With Schizophrenia | January 2012 | December 2018 |
| NCT03153046 | Completed | N/A | The Effects of Prebiotics on Cognitive Functioning and Weight Gain in Psychosis | May 8, 2017 | December 30, 2018 |
| NCT01186471 | Completed | Early Phase 1 | The Effect of Nicotine on Arousal, Cognition and Social Cognition in Schizophrenic Patients | May 2010 | March 2011 |
| NCT00650611 | Completed | Phase 2 | A Study of the Safety and Tolerability of Oral Ziprasidone in Children and Teens With Psychotic Disorders | December 2003 | March 2005 |
| NCT01503359 | Completed | Phase 2 | Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia | January 2012 | January 2016 |
| NCT01963676 | Completed | N/A | Transcranial Current Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia | January 2014 | October 2014 |
| NCT02417142 | Completed | Phase 4 | Exenatide Weekly Injections as an Adjunctive Treatment in Patients With Schizophrenia | September 2014 | July 2020 |
| NCT03221270 | Completed | N/A | Targeting Auditory Hallucinations With Alternating Current Stimulation | November 14, 2017 | January 5, 2021 |
| NCT00206128 | Completed | Phase 3 | Immediate Release (IR) to Sustained Release (SR) Switching Study: Study of Switching From IR Seroquel to SR Seroquel in Outpatients With Schizophrenia | November 2004 | February 2006 |
| NCT04248517 | Completed | N/A | Using mHealth to Optimize Pharmacotherapy Regimens | October 9, 2020 | January 20, 2023 |
| NCT00628290 | Completed | Phase 2 | Evaluation of the Antipsychotic Efficacy of Cannabidiol in Acute Schizophrenic Psychosis | October 2002 | March 2008 |
| NCT00077714 | Completed | Phase 3 | Trial Evaluating the Efficacy and Safety of 2 Fixed Doses of Paliperidone Extended-Release (ER) Tablets in the Treatment of Adult Patients With Schizophrenia | January 2004 | January 2005 |
| NCT00796185 | Completed | Phase 1 | As Study of the Pharmacokinetics of Paliperidone Extended-release and Risperidone Immediate-release Formulations | August 2003 | January 2004 |
| NCT02156908 | Completed | Phase 2 | D-serine and Cognitive Remediation in Schizophrenia | August 2014 | December 2015 |
| NCT00136994 | Completed | Phase 3 | IM and Oral in Acute Exacerbation of Schizophrenia (BIZET Study) | March 2003 | November 2005 |
| NCT01329393 | Completed | Phase 1 | Benefits Management for People With Psychiatric Disabilities | August 2010 | December 2013 |
| NCT00453609 | Completed | Phase 4 | Injectable Naltrexone Treatment of Alcohol Dependence in Serious Mental Illness (SMI) | April 2007 | October 2008 |
| NCT00338832 | Completed | Phase 3 | Effectiveness of a Lifestyle Intervention for Increasing Physical Activity in Adults With Schizophrenia | June 2006 | August 2011 |
| NCT03872596 | Completed | Phase 1 | Trial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar Disorder | March 27, 2019 | November 27, 2019 |
| NCT03166098 | Completed | The Role of Dysmyelination in Cognitive Impairment of Psychotic Spectrum Disorders | July 5, 2016 | March 1, 2022 | |
| NCT01209039 | Completed | Phase 1 | A Repeat Dose Positron Emission Tomography Study With GSK1144814 | July 1, 2009 | October 25, 2009 |
| NCT01110317 | Completed | Phase 1 | A Study of Paliperidone Blood Concentrations in Patients With Schizophrenia After Administration of Paliperidone Palmitate | July 2005 | March 2006 |
| NCT02640300 | Completed | Phase 4 | Switching Antipsychotics: Abrupt Discontinuation Versus Overlap | May 1999 | July 2004 |
| NCT01176721 | Completed | Phase 2 | Transcutaneous Non-invasive Vagus Nerve Stimulation (t-VNS) in the Treatment of Schizophrenia | March 2010 | February 2012 |
| NCT02002832 | Completed | Phase 3 | A Clinical Trial of Lurasidone in Treatment of Schizophrenia | December 2013 | November 2015 |
| NCT01860781 | Completed | Phase 4 | The Effect of Paliperidone Palmitate in Schizophrenia | August 2011 | December 2015 |
| NCT00500695 | Completed | Phase 1 | Enhancing Motivation To Quit Smoking In Smokers With Serious Mental Illness | May 2006 | October 2013 |
| NCT02775864 | Completed | Comparative Effectiveness of Adaptive Treatment Strategies for Schizophrenia | July 2015 | June 2018 | |
| NCT02288845 | Completed | Phase 2 | Receptor Occupancy of ITI-007 Using Positron Emission Tomography (PET) in Patients With Stable Schizophrenia | October 2014 | September 2015 |
| NCT00857064 | Completed | Subjective Well Being of Schizophrenic Patients in Greece | March 2009 | October 2009 | |
| NCT04284813 | Completed | N/A | Families With Substance Use and Psychosis: A Pilot Study | September 24, 2020 | July 7, 2022 |
| NCT00001920 | Completed | Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia | August 30, 1999 | June 2, 2010 | |
| NCT02192723 | Completed | N/A | A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia | June 2012 | June 2014 |
| NCT03075800 | Completed | N/A | Integration of Illness Management and Recovery Within ACT | June 7, 2011 | March 31, 2015 |
| NCT01032083 | Completed | Phase 4 | Antidepressant Controlled Trial for Negative Symptoms in Schizophrenia | July 2011 | January 2015 |
| NCT00637234 | Completed | Phase 2/Phase 3 | Oxcarbazepine as an Adjunct of Antipsychotic Therapy in Acute Schizophrenia | July 2004 | July 2008 |
| NCT00401973 | Completed | Phase 3 | Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With Olanzapine | November 2006 | September 2008 |
| NCT01143090 | Completed | Phase 3 | A Study of Subjects Switched to Lurasidone for the Treatment of Schizophrenia or Schizoaffective Disorder | August 2010 | |
| NCT00299702 | Completed | Phase 4 | Evaluation of Effectiveness of Risperdal® Consta® Compared to Abilify® Over a Two-year Period in Patients With Schizophrenia | February 2006 | January 2009 |
| NCT01891721 | Completed | N/A | Evaluating Two Types of Cognitive Training in Veterans With Schizophrenia | November 21, 2013 | June 30, 2018 |
| NCT01689389 | Completed | Description of the Use of Quetiapine Extended Release (XR) in Real-life Practice in France. An Observational Study | December 2012 | December 2014 | |
| NCT03701100 | Completed | N/A | The Effects of Bimodal tDCS on Illness Severity, Insight, Functional Outcomes, Neurocognition and HRV in Schizophrenia | July 17, 2017 | September 21, 2018 |
| NCT01245348 | Completed | Relative Effectiveness of Schizophrenia Therapy Study | December 2010 | December 2012 | |
| NCT01010620 | Completed | Screening Protocol for Research Participants | December 2009 | June 1, 2019 | |
| NCT02568709 | Completed | Early Phase 1 | Oxytocin MEG Study | February 2012 | December 2016 |
| NCT00892541 | Completed | Phase 1 | A Study of the Potential Effects of Trimethoprim on the Pharmacokinetics of ER OROS Paliperidone | October 2004 | November 2004 |
| NCT01626872 | Completed | Phase 2/Phase 3 | Long-Term Study of MP-214 in Patients With Schizophrenia | September 2012 | October 2016 |
| NCT00158366 | Completed | N/A | Reducing the Weight of Overweight Schizophrenia Patients | May 2004 | July 1, 2018 |
| NCT04418466 | Completed | Phase 1/Phase 2 | Safety, Tolerability, and Pharmacokinetics of Switching From Oral Risperidone to Risperidone Implant | April 1, 2021 | February 10, 2023 |
| NCT00690235 | Completed | Phase 4 | Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophrenia | November 2007 | August 2011 |
| NCT01268124 | Completed | Phase 1 | Study Evaluating The Safety and Tolerability of HTC-867 in Healthy Japanese Subjects | December 2008 | April 2009 |
| NCT01427088 | Completed | N/A | rTMS-induced Cumulative Pattern of sBDNF in Chronic Schizophrenia | August 2011 | November 2011 |
| NCT03164876 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetics of AUT00206 in Patients With Schizophrenia, and Also Explores the Effects of AUT00206 on Relevant Central Biomarkers. | April 20, 2017 | April 3, 2019 |
| NCT00538070 | Completed | N/A | A Study of the Effects of Sarcosine on Symptoms and Brain Glycine Levels in People With Schizophrenia | August 2007 | July 2012 |
| NCT02863094 | Completed | N/A | Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Schizophrenia Patients With Auditory Hallucinations | May 2016 | August 2021 |
| NCT01602263 | Completed | Transcranial Direct Current Stimulation (tDCS) and Cognitive Processing | January 2009 | March 2, 2023 | |
| NCT02091388 | Completed | Phase 1 | Bioavailability of LY03004 and Risperdal® Consta® | September 2014 | January 2015 |
| NCT02220712 | Completed | Phase 1 | A Multicenter Open-label Study Investigating the Pharmacokinetics and Safety of Aripiprazole IM Depot Formulation (OPC-14597 IMD) During Repeated Administration by Injection Into the Deltoid Muscle in Patients With Schizophrenia | July 2014 | April 2015 |
| NCT01663077 | Completed | Phase 4 | Clozapine Plasma Levels and the Relationship to the Genetic Polymorphism in Shizophrenic Patients | October 2012 | December 2016 |
| NCT00176436 | Completed | Phase 4 | Atomoxetine for Treatment of Weight Gain in Olanzapine or Clozapine Patients | February 2004 | March 2008 |
| NCT01317121 | Completed | Multi-site Communication Deficits in Schizophrenia | July 2011 | July 2017 | |
| NCT02532842 | Completed | Non-Interventional Study of Participants With Newly Diagnosed Schizophrenia Treated With Paliperidone Palmitate | July 2015 | September 2015 | |
| NCT05105542 | Completed | Phase 2 | M1 Schizophrenia PET Study | April 20, 2021 | October 31, 2023 |
| NCT02594696 | Completed | N/A | Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness | November 9, 2015 | November 1, 2017 |
| NCT01456897 | Completed | Phase 3 | A Long-term Trial of OPC-34712 in Patients With Schizophrenia | October 2011 | |
| NCT01494623 | Completed | N/A | The Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on Working Memory | May 2006 | November 2012 |
| NCT02744989 | Completed | N/A | STIM'ZO : Examining tDCS as an add-on Treatment for Persistent Symptoms in Schizophrenia | May 30, 2016 | October 19, 2022 |
| NCT00216671 | Completed | Phase 4 | Long-acting Injectable Risperidone in Patients With Schizophrenia After an Acute Episode | November 2005 | December 2009 |
| NCT02634320 | Completed | Phase 4 | A Study of Aripiprazole Lauroxil (Also Known as ARISTADA TM) in Subjects With Schizophrenia | December 2015 | July 11, 2017 |
| NCT00484302 | Completed | N/A | Specialized Addiction Treatment Versus Treatment as Usual for Young Patients With Cannabis Abuse and Psychosis | September 2007 | January 2011 |
| NCT01121042 | Completed | Phase 3 | Double Blind, Placebo-Controlled, Randomised Investigation of Ondansetron in Schizophrenia | July 2010 | August 2018 |
| NCT00169052 | Completed | N/A | Health Care Management and Rehabilitation Skills Training for Treating Serious Mental Illness in Older People | September 2001 | August 2006 |
| NCT02364544 | Completed | N/A | Improving Care and Reducing Cost Study | April 2013 | June 2015 |
| NCT02131129 | Completed | N/A | rTMS in First Episode Psychosis | April 30, 2014 | December 2016 |
| NCT00952757 | Completed | Changes in Hyperprolactinemia Secondary to Antipsychotics After Switching to Quetiapine | June 2007 | August 2008 | |
| NCT00350935 | Completed | Attention and Visual Perception in Schizophrenia: A Functional Magnetic Resonance Imaging (fMRI) Study | September 2006 | April 2009 | |
| NCT01888107 | Completed | Phase 3 | Maintenance of Efficacy With Risperidone Long Acting Injectable (R-LAI) in Patients With Schizophrenia or Schizoaffective Disorder | January 2005 | April 2007 |
| NCT00473434 | Completed | Phase 3 | An Open Label Multicentre Study to Determine the Dose Distribution of Paliperidone ER in Patients With Schizophrenia | April 2007 | August 2009 |
| NCT00590577 | Completed | Phase 3 | Effectiveness and Safety of 3 Fixed Doses (25 mg eq., 100 mg eq., and 150 mg eq.) of Paliperidone Palmitate in Patients With Schizophrenia | March 2007 | March 2008 |
| NCT00686140 | Completed | N/A | A Double-blind and Randomized Trial of Celecoxib Added to Risperidone in Treatment-naive First-episode Schizophrenia | June 2006 | March 2008 |
| NCT00155519 | Completed | A Psychopathological Study of Latent (Early) Schizophrenia: Clinical Pathology/Neuropsychological Dysfunctions | July 2002 | July 2002 | |
| NCT00249171 | Completed | Phase 4 | A Study of Risperidone in Combination With Lorazepam Compared With Standard Therapy for Emergency Treatment of Schizophrenic Patients | June 2001 | February 2003 |
| NCT05438160 | Completed | N/A | Exploratory Study of the Digital Therapeutics CT-155 in the Treatment of People With Schizophrenia | March 31, 2022 | July 31, 2022 |
| NCT00541398 | Completed | N/A | Antipsychotic Polypharmacy: Prevalence, Background and Consequences | January 2008 | October 2009 |
| NCT02969382 | Completed | Phase 2 | A Study to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic Adults With Schizophrenia | December 5, 2016 | July 31, 2018 |
| NCT00990925 | Completed | N/A | Lifestyle Modification for Weight Loss in Schizophrenia | October 2009 | February 2012 |
| NCT00320736 | Completed | Phase 4 | Galantamine for Cognition in People With Schizophrenia | January 2004 | May 2006 |
| NCT00300846 | Completed | Phase 4 | A Study of Adjunctive Treatment of Aripiprazole in Schizophrenic Patients | December 2005 | July 2007 |
| NCT02183844 | Completed | N/A | A System for Preference Assessment in Mental Health | June 16, 2014 | October 31, 2017 |
| NCT02037581 | Completed | N/A | Integrated Care Including Assertive Community Treatment in Early Psychosis | June 2011 | April 2015 |
| NCT00455702 | Completed | Phase 4 | Effects of Weekly Dosing of D-cycloserine on Cognitive Function in Individuals With Schizophrenia | July 2004 | April 2007 |
| NCT00905307 | Completed | Phase 2 | Study to Evaluate the Efficacy, Safety, and Tolerability of Oral OPC-34712 and Aripiprazole for Treatment of Acute Schizophrenia | July 2009 | November 2010 |
| NCT00295412 | Completed | Phase 4 | The Impact of Quetiapine on the Drug Abuse Patterns of Addicted Schizophrenic Patients | ||
| NCT03915938 | Completed | Phase 2/Phase 3 | Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain | January 2, 2017 | November 30, 2017 |
| NCT00525304 | Completed | N/A | A Self-Management Program for Adults With Both Schizophrenia and a Co-occurring Medical Condition | September 2007 | May 2015 |
| NCT00649844 | Completed | Phase 3 | A Study Comparing the Efficacy and Tolerability of Ziprasidone vs. Clozapine for the Treatment of Schizophrenia in Patients Who Continue to Have Symptoms on or Cannot Tolerate Other Antipsychotic Drugs | January 2003 | September 2004 |
| NCT00707382 | Completed | N/A | Effect of Genotyping for CYP450 Polymorphisms Versus Intense Clinical Monitoring on Antipsychotic Drug Treatment | February 2008 | December 2011 |
| NCT01903837 | Completed | Phase 2 | A Study of ALKS 3831 in Adults With Schizophrenia | June 2013 | March 2015 |
| NCT00249132 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Risperidone Compared With Haloperidol and Placebo in Patients With Chronic Schizophrenia | July 1991 | |
| NCT03576976 | Completed | N/A | Improving Accessibility and Personalization of CR for Schizophrenia | July 16, 2018 | May 30, 2022 |
| NCT00761605 | Completed | Phase 4 | Phase 4 Study to Evaluate Efficacy of Paliperidone Extended-Release(ER) in Schizophrenic Participants | April 2008 | October 2010 |
| NCT01606228 | Completed | Phase 3 | A Trial to Explore the Tolerability, Safety and Efficacy of Paliperidone Extended Release in Patients With Schizophrenia | December 2007 | December 2008 |
| NCT02722967 | Completed | Phase 2 | Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine System | March 2016 | September 2016 |
| NCT02109562 | Completed | Phase 3 | Randomized, Double-blind, Placebo Controlled, Multi-center and Tolerability of RBP-7000 in Schizophrenia Patients | April 2014 | November 2014 |
| NCT03557931 | Completed | Phase 2 | A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication | July 13, 2018 | October 21, 2019 |
| NCT00996242 | Completed | N/A | An Exploratory Open Label Study of Adjunctive L-lysine Treatment in Patients With Schizophrenia | September 2007 | March 2009 |
| NCT01752712 | Completed | N/A | Oxytocin and CBSST for People With Schizophrenia | January 2014 | August 2016 |
| NCT04184830 | Completed | N/A | Improving Cognition in Schizophrenia Using Non-invasive Brain Stimulation | September 2011 | March 2015 |
| NCT00051740 | Completed | N/A | Treating Thought Problems in Patients With Schizophrenia | February 2002 | October 2008 |
| NCT00300963 | Completed | Phase 2 | Effect Of Talnetant Versus Risperidone Versus Placebo On Psychotic Symptoms In Schizophrenic Patients | December 2004 | October 2005 |
| NCT02932605 | Completed | N/A | Endocannabinoid Control of Microglia Activation as a New Therapeutic Target in the Treatment of Schizophrenia | November 3, 2017 | January 31, 2020 |
| NCT01050582 | Completed | Phase 4 | A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in Children | October 2009 | July 2011 |
| NCT01051531 | Completed | Phase 3 | A Safety, Tolerability, and Treatment Response Study of Paliperidone Palmitate Administered to Patients With Schizophrenia | April 2010 | May 2013 |
| NCT02199704 | Completed | N/A | Self Directed Positive Parenting Program (Triple P) for Psychosis: A Clinical Case Series | June 2014 | November 2014 |
| NCT00199940 | Completed | Phase 4 | Safety And Efficacy Study Of Ziprasidone In Pediatric Psychotic Illness | December 2003 | April 2007 |
| NCT01192906 | Completed | Phase 3 | A Study of RO4917838 (Bitopertin) in Patients With Persistent, Predominant Negative Symptoms of Schizophrenia (WN25309) | December 2010 | July 2014 |
| NCT03287505 | Completed | Phase 1 | Aripiprazole IM Depot for Chinese Patients With Schizophrenia | June 23, 2017 | November 8, 2019 |
| NCT01100775 | Completed | Phase 2 | Effects of Galantamine on Cognition | May 2010 | August 21, 2014 |
| NCT01094249 | Completed | Phase 1 | A Drug Interaction Study of Valproic Acid and Paliperidone Extended-Release (ER) in Patients With Schizophrenia, Bipolar I Disorder, or Schizoaffective Disorder | February 2009 | April 2009 |
| NCT04369391 | Completed | Phase 1 | A Clinical Study to Investigate the Effect of an Investigational Drug on Electrocardiogram Intervals in Adults With Schizophrenia. | June 18, 2020 | November 10, 2020 |
| NCT01282307 | Completed | N/A | Improving Insight in Patients Diagnosed With Schizophrenia | February 2008 | July 2012 |
| NCT00893256 | Completed | Phase 4 | Effect of Add-on Citalopram to Risperidone on Negative Symptoms in Schizophrenia | December 2004 | September 2007 |
| NCT03788759 | Completed | Phase 2/Phase 3 | Alpha-lipoic Acid Adjunctive Therapy in Schizophrenia | September 1, 2019 | December 1, 2021 |
| NCT02181803 | Completed | Phase 1 | MK-8189 Multiple Dose Study in Healthy Volunteers and Schizophrenia Participants (MK-8189-003) | August 5, 2014 | April 23, 2015 |
| NCT02879604 | Completed | N/A | Cost-utility Study of a Group of Compensatory Cognitive Remediation in Schizophrenia | March 5, 2018 | March 28, 2023 |
| NCT01364792 | Completed | Phase 2 | To Rescue Cognition With Valaciclovir | April 2011 | August 2015 |
| NCT00051298 | Completed | Phase 3 | Olanzapine Versus Placebo in the Treatment of Adolescents With Schizophrenia | November 2002 | April 2005 |
| NCT00337350 | Completed | Phase 4 | Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment | September 2003 | January 2011 |
| NCT04411979 | Completed | N/A | Effects of 12 Weeks Walking on Cognitive Function in Schizophrenia | September 27, 2018 | October 15, 2019 |
| NCT00228462 | Completed | Phase 3 | Relapse Prevention, RoW: Study to Evaluate Prevention of Relapse in Patients in Stable Chronic Schizophrenia Receiving Either Seroquel or Placebo | March 2005 | April 2006 |
| NCT03356639 | Completed | Phase 1 | A Study to Assess the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of ASP6981 in Subjects With Schizophrenia | January 22, 2018 | May 30, 2018 |
| NCT00236353 | Completed | Phase 3 | Evaluation of the Efficacy and Safety of Risperidone Injections Given Once a Month to Adults With Schizophrenia or Schizoaffective Disorder | May 2002 | December 2003 |
| NCT00236457 | Completed | Phase 3 | A Study Comparing the Efficacy of Long-acting Injectable Risperidone and Olanzapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder | November 2000 | December 2002 |
| NCT03629951 | Completed | A Study for Schizophrenia Relapse Prediction | November 29, 2018 | December 31, 2021 | |
| NCT01660880 | Completed | Validation of Receptor Occupancy Simulation | December 2012 | April 2014 | |
| NCT04637724 | Completed | N/A | Transcranial Weak Current Stimulation Treatments for Working Memory Dysfunction in Schizophrenia | November 29, 2019 | September 10, 2023 |
| NCT00051233 | Completed | Phase 2 | Treatment of Schizophrenia Through Internet-Based Psychoeducation | January 2003 | January 2005 |
| NCT00791349 | Completed | Phase 1 | A Study of QT and QTc Intervals in Patients Administered Immediate Release Paliperidone | February 2005 | May 2005 |
| NCT02743143 | Completed | N/A | Long-Term Exercise Training Therapy Versus Usual Care in Patients With Schizophrenia | December 2015 | June 2018 |
| NCT01175642 | Completed | Early Phase 1 | Cognitive Remediation and Functional Skills Training in Schizophrenia | July 2007 | September 2010 |
| NCT04510298 | Completed | Phase 1 | A Study of the Safety, PK, and Exploratory Efficacy of SP-624 in Acutely Psychotic Adult Subjects With Schizophrenia | October 15, 2020 | April 15, 2021 |
| NCT00485498 | Completed | Phase 4 | Managing Acute Schizophrenia, a Comparison Between Two Atypical Antipsychotics | April 2003 | December 2003 |
| NCT01244854 | Completed | N/A | Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental Illness | October 1, 2010 | March 6, 2015 |
| NCT00472862 | Completed | Phase 3 | Neurocognitive Training Integrated in OPUS Treatment Versus OPUS Treatment-as-usual | January 2007 | April 2010 |
| NCT00325689 | Completed | Phase 4 | Aripiprazole Used as Dual Therapy in the Treatement of Patients With Chronic Stable Schizophrenia or Schizoaffective Disorder. | July 2006 | October 2007 |
| NCT00183625 | Completed | Phase 4 | Supported Employment and Skills Training in Conjunction With Pharmacotherapy in Schizophrenia Patients | June 2000 | September 2006 |
| NCT04072575 | Completed | Phase 3 | A Study of Paliperidone Palmitate 6-Month Formulation | September 19, 2019 | May 3, 2022 |
| NCT00056498 | Completed | Phase 4 | Risperidone Treatment in Schizophrenia Patients Who Are Currently Taking Clozapine | December 2001 | December 2007 |
| NCT01066403 | Completed | N/A | Adjuvant Therapy With Pergolide in Treating Cognitive Deficits in Schizophrenia | October 2003 | March 2008 |
| NCT00378183 | Completed | Phase 4 | A Study Comparing Three Strategies to Switch Patients With Schizophrenia or Schizoaffective Disorder to Risperidone After Unsuccessful Treatment With Olanzapine. | February 2001 | May 2002 |
| NCT01506765 | Completed | Phase 1 | Schizophrenia, Related Troubles and Glutathione: Clinical Trial. Effects of Oral Administration of N-Acetylcysteine (NAC) on the Brain Glutathione Level and on the Symptoms of Schizophrenia | August 2003 | September 2006 |
| NCT01377233 | Completed | Phase 2 | Study of the Safety, Tolerability, and Pharmacokinetics of Once Weekly Zicronapine in Patients With Schizophrenia | July 2011 | |
| NCT00875498 | Completed | N/A | Intermittent Theta Burst Stimulation (iTBS) for the Treatment of Negative Symptoms in Schizophrenia | November 2008 | July 2015 |
| NCT02873208 | Completed | Phase 3 | A Phase 3, Long-term Safety and Tolerability Study of ALKS 3831 in Adults With Schizophrenia | August 7, 2016 | October 17, 2019 |
| NCT00137020 | Completed | Phase 4 | Clinical Effect Of Cross Titration Of Antipsychotics With Ziprasidone In Schizophrenia Or Schizoaffective Disorder | November 2004 | April 2006 |
| NCT05206734 | Completed | Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health | January 5, 2022 | August 15, 2023 | |
| NCT00044187 | Completed | Phase 4 | The Assessment of a Weight-Gain Agent for the Treatment of Olanzapine-Associated Anti-Obesity Agent in Patients With Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, and Bipolar I Disorder | April 2001 | September 2003 |
| NCT05282329 | Completed | N/A | Efficacy of tACS for Treatment of Auditory Hallucinations in Refractory Schizophrenia | September 1, 2020 | September 21, 2022 |
| NCT03809325 | Completed | A Survey to Collect Treatment Experience Feedback From Patients, Physicians, Nurses and Carers After Switching to Paliperidone Palmitate 3-monthly | November 21, 2018 | July 12, 2019 | |
| NCT02219009 | Completed | Phase 2 | Open-label Study to Assess Usability of the Medical Information Device #1 (MIND1) System in Adults With Schizophrenia On Oral Aripiprazole | August 2014 | July 2015 |
| NCT01485640 | Completed | Phase 3 | Lurasidone Extended Use Study | June 2011 | February 2014 |
| NCT00921804 | Completed | Phase 2 | Study to Assess the Efficacy, Safety, and Tolerability of AZD8529 in Adult Schizophrenia Patients | June 2009 | May 2010 |
| NCT01793324 | Completed | EMR Data to Assess Monitoring of Patients Treated With Quetiapine | April 2012 | June 2013 | |
| NCT00937716 | Completed | Treatment Response in Schizophrenia: Bridging Imaging and Postmortem Studies | October 2008 | June 30, 2021 | |
| NCT01055509 | Completed | N/A | Compensatory Strategies Applied to Cognitive Impairment in Schizophrenia | January 2009 | August 2011 |
| NCT05124470 | Completed | N/A | Cognitive Remediation Method by Rhythmic, Vocal and Embodied Musical Learning for Stabilized Schizophrenic Patients | December 1, 2021 | October 21, 2022 |
| NCT02968602 | Completed | Phase 4 | Minocycline and Tobacco Craving in Smokers With Schizophrenia | March 31, 2017 | July 23, 2019 |
| NCT00595504 | Completed | Phase 4 | Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia | January 2008 | March 2010 |
| NCT00049946 | Completed | Phase 2 | Schizophrenia Study In Adults | October 2002 | April 2003 |
| NCT01387542 | Completed | Phase 4 | Safety and Efficacy Study of Paliperidone Extended Release (ER) Among Thai Schizophrenia Participants | August 2009 | September 2010 |
| NCT00490516 | Completed | Phase 2 | ACP-104 in Acutely Psychotic Subjects With Schizophrenia | June 2007 | February 2008 |
| NCT03003156 | Completed | N/A | 50 Hz vs. 25 Hz Magnetic Seizure Therapy for Schizophrenia | February 2016 | March 2017 |
| NCT00383747 | Completed | Phase 4 | The Effects of Nicotine on Cognition in Schizophrenia | April 2004 | January 2009 |
| NCT00254241 | Completed | Phase 4 | Safety and Efficacy of Seroquel in First Episode Schizophrenia | May 2002 | June 2006 |
| NCT02409823 | Completed | Clinical Registry of Patients Under Treatment With Atypical Antipsychotics | February 2015 | August 2015 | |
| NCT00527020 | Completed | Phase 1 | First Time in Human Study With GSK1018921 | August 10, 2007 | July 12, 2008 |
| NCT02413164 | Completed | N/A | Multimodal Physical Therapy Program in Schizophrenia | March 1, 2017 | May 1, 2018 |
| NCT03868358 | Completed | N/A | Effect of Intermittent Theta Burst Stimulation (iTBS) for Alleviating Symptoms of Schizophrenia Patients | May 21, 2017 | March 30, 2021 |
| NCT03930251 | Completed | N/A | Cognitive Remediation for Coordinated Specialty Care | June 1, 2019 | December 31, 2023 |
| NCT00423033 | Completed | Qualitative Analysis on the Experiences of Employment Among Schizophrenic Patients | March 2007 | September 2007 | |
| NCT00255918 | Completed | Phase 1 | Investigation of the Drug Dimethoxbenzylidene Anabaseine in Treating Schizophrenia Patients | March 2004 | October 2005 |
| NCT02051387 | Completed | Phase 1 | Cannabidiol as a Different Type of an Antipsychotic: Drug Delivery and Interaction Study | January 2013 | August 2017 |
| NCT00761189 | Completed | Phase 4 | PaliperidoNe Extended-Release [ER] Dosing and Clinical Response in Acute Schizophrenia | February 2008 | July 2010 |
| NCT00014001 | Completed | Phase 4 | CATIE- Schizophrenia Trial | December 2000 | December 2004 |
| NCT00240708 | Completed | Phase 3 | A Study of the Efficacy and Safety of Long-acting Injectable Risperidone and Risperidone Tablets in Patients With Schizophrenia | June 2004 | April 2006 |
| NCT00646581 | Completed | Phase 4 | Effect of Single Dose Intranasal Insulin On Cognitive Function | October 2006 | January 2010 |
| NCT03967431 | Completed | N/A | Effects of Narrative Enhancement and Cognitive Therapy (NECT) on Self-stigma in Patients With Schizophrenia | October 20, 2018 | July 18, 2019 |
| NCT02201888 | Completed | N/A | Effects of a Cognitive Rehabilitation Program: a Neurocognitive Study | January 2010 | February 2014 |
| NCT00618280 | Completed | Phase 1/Phase 2 | Social Cognition,Attentional Network and Nicotine Drug Dependency - A Pharmacological Clinical Trail | January 2008 | August 2010 |
| NCT00690365 | Completed | Safety and Efficacy of Switching to Quetiapine in Outpatients With Schizophrenia | June 2007 | April 2008 | |
| NCT00645307 | Completed | Phase 3 | A 52 Week Open Label Extension Trial Following the Recurrence Prevention Study R076477-SCH-301 to Evaluate the Safety and Tolerability of Paliperidone ER in Subjects With Schizophrenia. | May 2004 | August 2006 |
| NCT02845440 | Completed | N/A | Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness | July 14, 2016 | January 12, 2021 |
| NCT00536783 | Completed | Schizophrenia Sensory Gating Deficit With Quetiapine | April 2004 | March 2006 | |
| NCT00289861 | Completed | Phase 4 | Risperidone Augmentation in Patients With Schizophrenia | February 2003 | March 2007 |
| NCT00328978 | Completed | Phase 3 | Seroquel STACK Study in Schizophrenic or Schizoaffective Subjects | October 2003 | September 2005 |
| NCT01794897 | Completed | Phase 4 | Valacyclovir Augmentation for Cognitive and Functional Remediation in Schizophrenia | February 2013 | September 2016 |
| NCT01854944 | Completed | Phase 1 | PET Trial to Assess the Receptor Occupancy of Brexpiprazole in Adult Subjects With Schizophrenia | September 2013 | August 2014 |
| NCT01911429 | Completed | Phase 3 | Pediatric Schizophrenia Efficacy and Safety Study | August 2013 | December 2015 |
| NCT00495352 | Completed | Phase 4 | The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia | January 2006 | December 2008 |
| NCT00604279 | Completed | Phase 3 | A Comparative Study of Paliperidone Palmitate and Risperidone Long Acting Injection (LAI) in Participants With Schizophrenia | January 2008 | January 2009 |
| NCT00802100 | Completed | Phase 4 | Comparison of Optimal Antipsychotic Treatments for Adults With Schizophrenia | December 2008 | October 2009 |
| NCT01793935 | Completed | N/A | Withania Somnifera: an Immunomodulator and Anti-inflammatory Agent for Schizophrenia | April 2013 | July 7, 2016 |
| NCT03059771 | Completed | N/A | Mobile Enhancement of Motivation in Schizophrenia | February 28, 2017 | January 16, 2018 |
| NCT02167724 | Completed | N/A | Multicentre Evaluation of Bucco-dental Health in Patients With Schizophrenia in Côte d'Or | September 2014 | January 2016 |
| NCT01101659 | Completed | Phase 1 | Ketamine Challenge Study With JNJ-40411813 | February 2010 | July 2010 |
| NCT00485901 | Completed | Phase 3 | Comparison of Intramuscular Olanzapine and Intramuscular Haloperidol in Patients With Schizophrenia | July 2004 | January 2005 |
| NCT03940898 | Completed | N/A | The Mid-term Effect of Repeated Transcranial Magnetic Stimulation on Schizophrenia | July 1, 2017 | September 30, 2018 |
| NCT04865835 | Completed | Phase 1 | A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia. | May 12, 2021 | May 3, 2022 |
| NCT01435928 | Completed | Phase 3 | PEARL Schizophrenia Maintenance | September 2011 | August 2013 |
| NCT00688324 | Completed | Phase 4 | Biomarker Study of Acamprosate in Schizophrenia | June 2008 | February 2012 |
| NCT01242371 | Completed | N/A | Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia | August 2010 | August 2012 |
| NCT01714661 | Completed | Phase 3 | Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy | October 2012 | December 2015 |
| NCT05563818 | Completed | Using Speech to Monitor Symptom Severity in Arabic Speaking Patients With Schizophrenia | November 9, 2021 | December 20, 2022 | |
| NCT02823041 | Completed | N/A | Enhancing Cognitive Training Through Exercise Following a First Schizophrenia Episode | October 13, 2016 | June 30, 2023 |
| NCT02326389 | Completed | N/A | Exercise and Cognitive Training | May 2015 | November 2017 |
| NCT00791440 | Completed | N/A | Recovery From Psychosis in Schizophrenia - The Impact of Cognitive-Behavioral Therapy | November 2008 | June 2012 |
| NCT01446328 | Completed | Phase 4 | Bergen Psychosis Project 2 - The Best Intro Study | October 2011 | December 2017 |
| NCT02090335 | Completed | N/A | Health Promotion and Fitness for Younger and Older Adults With SMI | May 2007 | May 2013 |
| NCT01749098 | Completed | Phase 1 | A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers | December 2012 | February 2014 |
| NCT00044044 | Completed | Phase 2 | A Comparison of Study Drug With Placebo and Haloperidol in Patients With Schizophrenia | July 2002 | May 2003 |
| NCT03839251 | Completed | Phase 4 | Effectiveness of Aripiprazole Long-acting Injection in Recent Onset and Chronic Schizophrenia Patients | June 1, 2018 | September 30, 2020 |
| NCT01607424 | Completed | N/A | Specific Cognitive Remediation for Schizophrenia | December 2008 | October 2011 |
| NCT00167934 | Completed | N/A | Determining Metabolic Effects of Valproate and Antipsychotic Therapy | December 2004 | December 2008 |
| NCT02072954 | Completed | Phase 2/Phase 3 | Bioequivalence Fasting Study in Patients | November 2013 | June 2014 |
| NCT00780884 | Completed | N/A | Influence of Acupuncture on Emotional Measures and Quality of Sleep Among Schizophrenia Patients | April 2008 | April 2009 |
| NCT03772951 | Completed | Phase 4 | The Efficacy of Computerized Cognitive Remediation Therapy for Chronic Schizophrenia | January 10, 2019 | March 31, 2021 |
| NCT00428350 | Completed | Phase 4 | Study of Efficacy and Safety of Seroquel (Quetiapine Fumarate) as Mono-Therapy for Acute Schizophrenic | December 2006 | September 2007 |
| NCT00616798 | Completed | Phase 2 | A Study of RO4917838 in Combination With Antipsychotic Treatment in Patients With Schizophrenia. | March 2008 | February 2010 |
| NCT01281527 | Completed | Phase 3 | Paliperidone Palmitate Flexible Dosing in Schizophrenia | November 2010 | November 2013 |
| NCT00253136 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Long-acting Injectable Risperidone Versus Placebo in the Treatment of Patients With Schizophrenia | November 1999 | December 2000 |
| NCT03666715 | Completed | A Study to Analyze the Impact of Treatment With Paliperidone Palmitate on Clinical Outcomes and Hospital Resource Utilization in Adult Participants With Schizophrenia in Portugal | August 7, 2018 | May 31, 2021 | |
| NCT01923025 | Completed | Phase 1 | A PET Study With RO5545965 in Healthy Male Volunteers | August 2013 | November 2013 |
| NCT02787135 | Completed | N/A | Efficacy and Mechanisms of Change of an Emotion-oriented Version of Cognitive-behavioral Therapy for Psychosis | May 1, 2016 | December 31, 2019 |
| NCT00984373 | Completed | Epidemiology of Schizophrenia in Bulgaria | September 2009 | November 2009 | |
| NCT03656770 | Completed | N/A | Measuring Beliefs and Norms About Persons With Mental Illness | December 13, 2016 | June 8, 2018 |
| NCT03273439 | Completed | N/A | A Study of rTMS for Cognitive Deficits in Chronic Patients With Schizophrenia | July 1, 2012 | June 30, 2015 |
| NCT04136873 | Completed | Phase 1 | A Multiple Ascending Dose Trial of CVL-231 in Subjects With Schizophrenia | October 15, 2019 | June 3, 2021 |
| NCT04972227 | Completed | Phase 1 | Study to Assess the Safety and Pharmacokinetics of CY6463 in Participants With Stable Schizophrenia | September 10, 2021 | April 18, 2022 |
| NCT02033382 | Completed | Biomarkers in First Episode Schizophrenia | July 2012 | December 2014 | |
| NCT01934023 | Completed | Phase 2 | Effects of Varenicline on Plasticity in Schizophrenia | September 2013 | August 2015 |
| NCT02507349 | Completed | N/A | Person-Centered Versus Measurement-Based Care in Mental Health | August 2014 | March 31, 2017 |
| NCT00404573 | Completed | Phase 2 | Study Evaluating RGH-188 in the Treatment of Patients With Schizophrenia | November 2006 | |
| NCT03338673 | Completed | N/A | Brain Stimulation and Cognitive Training | October 11, 2018 | September 27, 2019 |
| NCT01959035 | Completed | Phase 3 | Aripiprazole Once-monthly in Patients With Schizophrenia | October 2013 | March 2015 |
| NCT02398279 | Completed | N/A | L-arginine add-on Therapy in Patients With Schizophrenia | June 2011 | April 2013 |
| NCT02151656 | Completed | Phase 2 | F17464 in Acute Schizophrenia Trial | June 2014 | December 2015 |
| NCT00071747 | Completed | Phase 3 | Clinical Study Of Schizophrenia in Both Men and Women | August 2003 | January 2005 |
| NCT01973270 | Completed | N/A | Community-Based Cognitive Training in Early Schizophrenia | December 2013 | August 21, 2019 |
| NCT00236379 | Completed | Phase 4 | A Study of the Effects of Risperidone and Olanzapine on Blood Glucose (Sugar) in Patients With Schizophrenia or Schizoaffective Disorder | August 2003 | |
| NCT01948024 | Completed | Phase 1 | Bio-equivalence Study Between SAPHRIS and Asenapine | July 2013 | August 2013 |
| NCT02484521 | Completed | N/A | Prepulse Inhibition (PPI) of Startle Reflex in Schizophrenia Patients Related to Type of Treatment and Illness Duration | June 2015 | June 2019 |
| NCT00848484 | Completed | Phase 2 | Treatment of Cognitive Impairment in Men With Schizophrenia (MK5757-005)(COMPLETED) | October 2008 | June 2009 |
| NCT02796417 | Completed | N/A | The Efficacy of REHACOP Program in Schizophrenia | March 2012 | April 2014 |
| NCT02978599 | Completed | Phase 1 | Clinical Trial of AVL-3288 in Schizophrenia Patients | November 2016 | November 2, 2018 |
| NCT01915017 | Completed | N/A | Interventions to Improve Functional Outcome and Persistent Symptoms in Schizophrenia | April 2008 | July 2013 |
| NCT01082289 | Completed | Phase 1 | Digoxin Drug-Drug Interaction With Lurasidone HCl | September 2008 | October 2008 |
| NCT01517360 | Completed | Phase 1 | Pharmacological Approach to Improve the Outcome of Social Cognition Training | January 2012 | February 2013 |
| NCT00914238 | Completed | N/A | Extended Specialized Assertive Intervention for First Episode Psychosis | July 2009 | October 2016 |
| NCT01216891 | Completed | N/A | Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis | October 2010 | August 2016 |
| NCT01082250 | Completed | Phase 1 | The Bioequivalence Of Two Different Lurasidone Formulations In Patients | July 2008 | September 2008 |
| NCT03870880 | Completed | Phase 3 | Study to Evaluate the Efficacy and Safety of Risperidone ISM® in Patients With Acute Schizophrenia: Open Label Extension | August 25, 2017 | January 8, 2020 |
| NCT01776112 | Completed | N/A | Enhancing Synaptic Plasticity and Cognition in Schizophrenia | January 2011 | August 2014 |
| NCT00269035 | Completed | Phase 1 | SPECT Study With SB-773812 In Schizophrenic Patients | June 21, 2005 | May 26, 2007 |
| NCT01810380 | Completed | Phase 3 | Brexpiprazole in Patients With Acute Schizophrenia | March 2013 | December 2014 |
| NCT00328952 | Completed | Changes in Auditory Verbal Hallucination During Atypical Antipsychotic Treatment of Patients With Schizophrenia | August 2004 | August 2008 | |
| NCT05406440 | Completed | Phase 1 | A Study of MK-8189 in Participants With Schizophrenia (MK-8189-014) | July 12, 2022 | February 24, 2023 |
| NCT00641745 | Completed | Phase 3 | Lurasidone HCl - A Long Term Safety Phase 3 Study of Patients With Clinically Stable Schizophrenia | March 2008 | July 2010 |
| NCT00161031 | Completed | N/A | Atomoxetine as an Adjunct to Novel Antipsychotic Medication in the Treatment of Cognitive Deficits of Schizophrenia | April 2004 | December 2006 |
| NCT02308956 | Completed | Phase 3 | Task Sharing for the Care of Severe Mental Disorders in a Low-income Country | March 2015 | November 16, 2017 |
| NCT00313391 | Completed | Phase 4 | Risperdal Consta and Health Care Utilization in Patients With Schizophrenia | December 2005 | |
| NCT00833976 | Completed | Phase 4 | Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia | July 2009 | March 2013 |
| NCT01667601 | Completed | N/A | Mindfulness-based Illness Management Program for Schizophrenia | August 2010 | April 2017 |
| NCT01362439 | Completed | Phase 4 | Paliperidone Extended Release in Schizophrenia Participants With Duration of Illness Less Than 10 Years | January 2009 | March 2010 |
| NCT01942382 | Completed | Phase 1 | A Clinical Pharmacology Study of JNS010 (Paliperidone Palmitate) in Patients With Schizophrenia | April 2009 | March 2010 |
| NCT00399334 | Completed | PROFILe3: Epidemiologic Survey in Patients With Schizophrenia or Schizoaffective Disorders | June 2005 | December 2005 | |
| NCT00407277 | Completed | N/A | Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia | February 2007 | |
| NCT00999895 | Completed | A Study Evaluating the Treatment Selection and Outcome When Changing Antipsychotic Treatment in Schizophrenic Patients | October 2009 | September 2010 | |
| NCT00372151 | Completed | Phase 3 | L-Theanine in the Management of Schizophrenia | October 2006 | December 2008 |
| NCT00193713 | Completed | Phase 3 | Bifeprunox in the Treatment of Schizophrenia | May 2005 | November 2006 |
| NCT00690274 | Completed | Phase 2 | Study to Demonstrate Cognitive Enhancing Effects of BF2.649 | June 2008 | October 2011 |
| NCT00280813 | Completed | N/A | Alcohol Use Disorders in Schizophrenia | March 2004 | May 2007 |
| NCT04127058 | Completed | Phase 1 | Evaluating a New Iloperidone Titration Scheme in Bipolar I Disorder or Schizophrenia | October 7, 2019 | November 27, 2019 |
| NCT00148083 | Completed | Phase 3 | Effects of Risperdal Consta on Ability to Benefit From Social Skills Training in Schizophrenia | September 2005 | March 2006 |
| NCT01927276 | Completed | N/A | Randomized Controlled Trial of a Gluten Free Diet In Patients With Schizophrenia Who Are Gliadin-Positive | September 1, 2013 | May 1, 2017 |
| NCT00784238 | Completed | Phase 4 | Efficacy Study of Paliperidone to Evaluate Subjective Change in Well-being and Drug Attitude in Schizophrenic Participants | April 2008 | January 2011 |
| NCT00149292 | Completed | Phase 2 | Study of LY2140023 in Schizophrenia Comparing LY2140023, Olanzapine, and Placebo | August 23, 2005 | July 17, 2006 |
| NCT00237809 | Completed | Phase 3 | D-Serine Treatment of Negative Symptoms and Cognitive Deficits in Schizophrenia | September 2002 | September 2012 |
| NCT02415764 | Completed | Phase 1 | OnTrack>An Online Role-Playing Game: A Small Business Innovation Research (SBIR) Grant | June 2015 | March 2016 |
| NCT05556941 | Completed | N/A | Metacognitive Intervention for Individuals With Severe Mental Disorders | October 1, 2015 | April 30, 2016 |
| NCT01886417 | Completed | Auditory Verbal Hallucinations in Schizophrenia | October 2009 | March 2015 | |
| NCT03101319 | Completed | N/A | Role of Vitamin D Supplementation in Schizophrenia | April 8, 2019 | June 22, 2021 |
| NCT04526067 | Completed | N/A | In-person vs. Remote Wellness Support | November 24, 2020 | November 11, 2022 |
| NCT03062267 | Completed | N/A | Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness | October 1, 2017 | May 31, 2020 |
| NCT03510741 | Completed | Phase 2 | Sodium Benzoate and/or N-Acetylcysteine Added to TAU in Patients With Early Schizophrenia Spectrum Disorder. | January 1, 2019 | March 30, 2021 |
| NCT01150734 | Completed | Neuromodulation in Depressed and Schizophrenic Patients - Changing MEP (Muscle Evoked Potentials) by tDCS (Transcranial Direct Current Stimulation) | October 2009 | January 2011 | |
| NCT02773108 | Completed | Somatic Comorbidities in Psychiatric Patients | May 2016 | December 2018 | |
| NCT00779506 | Completed | Phase 4 | Study of the Efficacy and Safety of Quetiapine Fumarate Extended Release (Seroquel XR) | November 2008 | July 2009 |
| NCT01812642 | Completed | Phase 2 | A Pharmacokinetics Study to Evaluate Safety and Tolerability of JNJ-37822681 in Participants With Stable Schizophrenia | July 2008 | December 2008 |
| NCT00829400 | Completed | N/A | Cognitive Training to Enhance VA Work Program Outcomes | May 2008 | December 2016 |
| NCT00888693 | Completed | Phase 1 | A Multiple Dose Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ABT-288 in Stable Subjects With Schizophrenia | November 2008 | |
| NCT01898299 | Completed | N/A | TDCS for Auditory Hallucinations in Schizophrenia | May 2013 | August 14, 2018 |
| NCT00130923 | Completed | Phase 4 | Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder | September 2005 | July 2010 |
| NCT02538445 | Completed | N/A | Can we Forget? Directed Forgetting and Embodied Cognition in Schizophrenia | May 2011 | December 2012 |
| NCT01173874 | Completed | Phase 3 | Efficacy of Cognitive Remediation in Patients With Schizophrenia or Schizoaffective Disorder Stabilized on Lurasidone | July 2010 | November 2013 |
| NCT02336581 | Completed | N/A | Researching the Effectiveness of Acceptance-Based Coping During Hospitalization | March 2015 | September 2017 |
| NCT00937755 | Completed | The Study of Atypical Antipsychotics-induced Metabolic Disturbances | March 2006 | May 2009 | |
| NCT00089869 | Completed | Phase 1/Phase 2 | A Combination of Two Currently Approved Drugs to Enhance the Treatment of Schizophrenia | ||
| NCT00357006 | Completed | Phase 2 | A Definitive Estrogen Patch Study (ADEPT) | July 2006 | December 2013 |
| NCT00034892 | Completed | Phase 3 | CAFE Comparison of Atypicals in First Episode of Psychosis | March 2002 | March 2005 |
| NCT00541996 | Completed | Phase 1 | Study Comparing Bioavailability of Oral Formulations of Vabicaserin | August 2007 | October 2007 |
| NCT01878513 | Completed | N/A | Prospective Cytochrome P450 Genotyping and Clinical Outcomes in Patients With Psychosis | September 23, 2009 | July 31, 2018 |
| NCT00312962 | Completed | Phase 1/Phase 2 | Effectiveness of Targeted Cognitive Training for Neurological Deficits in People With Schizophrenia | April 2004 | March 2013 |
| NCT00740259 | Completed | Phase 4 | Efficacy and Tolerability of Flunarizine for the Treatment of Schizophrenia: Comparison With Haloperidol | September 2004 | May 2007 |
| NCT00802919 | Completed | Phase 4 | Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors | September 2008 | December 2013 |
| NCT03288779 | Completed | N/A | Theta Burst Stimulation for Schizophrenia | October 24, 2017 | June 30, 2018 |
| NCT00105794 | Completed | N/A | Psychiatric Advance Directives for Improved Mental Health Care | March 2004 | June 2007 |
| NCT01432444 | Completed | Phase 3 | Open-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics Versus IM Depot Aripiprazole | September 2011 | December 2013 |
| NCT03131505 | Completed | INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1 | February 22, 2017 | February 21, 2018 | |
| NCT00382915 | Completed | Measuring Smoking Behavior in People With Schizophrenia and Bipolar Disorder | October 2006 | December 2010 | |
| NCT00929955 | Completed | Phase 1 | Role of Anti-Inflammatory Agents in Patients With Schizophrenia | June 2009 | September 2010 |
| NCT02175251 | Completed | N/A | Low and High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Resistant Auditory Hallucination in Schizophrenia | February 2014 | September 29, 2017 |
| NCT00396565 | Completed | Phase 3 | A Study to Evaluate Effectiveness and Safety of ER OROS Paliperidone in Patients With Schizophrenia | July 2006 | November 2007 |
| NCT00809731 | Completed | Observational Study to Evaluate Efficacy and Remission Status for Schizophrenia Patients Under Atypical Treatment | December 2008 | September 2010 | |
| NCT00689325 | Completed | Evaluating Subjective Well-being in Schizophrenic Patients Treated With quetiapineXR® and Other Atypical Antipsychotics | April 2008 | January 2010 | |
| NCT00839852 | Completed | Phase 2 | A Study of Cariprazine in Patients With Chronic Stable Schizophrenia | May 31, 2009 | August 31, 2010 |
| NCT01606254 | Completed | Phase 2 | A Pharmacokinetic and Safety Study of Paliperidone Palmitate (JNS010) in Participants With Schizophrenia | January 2007 | April 2008 |
| NCT00406315 | Completed | Phase 4 | Study Evaluating The Safety, Tolerability, And Efficacy Of Switching From Quetiapine To Ziprasidone | November 2006 | March 2009 |
| NCT05537428 | Completed | N/A | Song-making In a Group (SING) | October 31, 2020 | September 1, 2022 |
| NCT01819818 | Completed | A Study to Observe the Safety and Tolerability of Paliperidone Palmitate (Invega Sustenna) in Korean Schizophrenic Patients | May 23, 2011 | November 29, 2019 | |
| NCT00915512 | Completed | Phase 4 | A Phase 4 Study to Evaluate Response to Treatment and Safety of Paliperidone Extended-Release in Participants With Schizophrenia | May 2009 | October 2011 |
| NCT02661789 | Completed | N/A | Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression | January 2011 | December 2012 |
| NCT00615433 | Completed | Phase 3 | Lurasidone HCl A Phase 3 Study of Patients With Acute Schizophrenia | January 2008 | January 2010 |
| NCT02930005 | Completed | Phase 2 | Pentosan Polysulfate Sodium and Meclofenamic Acid as Treatments in Patients With Psychotic Disorders | August 7, 2015 | October 6, 2016 |
| NCT04941352 | Completed | N/A | Motivational Interviewing in Patients With Schizophrenia | September 17, 2019 | June 11, 2021 |
| NCT01206517 | Completed | Phase 1 | A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Sublingual Asenapine in a Pediatric Population With Schizophrenia or Bipolar I Disorder (P06522 AM1) | July 18, 2010 | August 4, 2011 |
| NCT01369966 | Completed | Brain Circuits in Schizophrenia and Smoking | May 16, 2011 | December 24, 2014 | |
| NCT03527186 | Completed | Phase 1 | Comparative Bioavailability of Risperidone | July 9, 2018 | April 6, 2019 |
| NCT02034474 | Completed | Phase 4 | Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia | February 2014 | February 6, 2017 |
| NCT01263080 | Completed | Phase 4 | Evaluation of Mirtazapine and Folic Acid for Schizophrenia: | November 2010 | December 2012 |
| NCT00316238 | Completed | Phase 2 | A Study Using Rapid Acting Intramuscular Olanzapine in Agitated Patients With Schizophrenia | April 2006 | May 2007 |
| NCT05901922 | Completed | N/A | The Effect of Social Skills Intervention on Praxis and Social Functioning in Individuals With Schizophrenia | March 7, 2023 | July 15, 2023 |
| NCT00843687 | Completed | Phase 3 | A Comparison of the Pharmacokinetics and Safety of Long-acting Injectable Risperidone When Administered to Gluteal or Deltoid Intramuscular Injection Sites in Stable Schizophrenia Patients. | September 2005 | March 2007 |
| NCT00954122 | Completed | Phase 4 | Efficacy and Safety of SEROQUEL Extended Release (XR) in Acute Schizophrenia | September 2009 | April 2010 |
| NCT05229484 | Completed | N/A | Effects of an Integrated Multimodal Lifestyle Intervention for Management of Violence in Schizophrenia | August 15, 2016 | August 14, 2018 |
| NCT00174889 | Completed | Phase 1 | Pregnenolone in the Management of Schizophrenia Patients | January 2005 | May 2007 |
| NCT00485810 | Completed | Phase 1/Phase 2 | Examining Rapid Acting Intra-Muscular Olanzapine in Japanese Patients With Schizophrenia | June 2004 | November 2004 |
| NCT01850953 | Completed | Phase 4 | Effects of Varenicline on Smoking Lapse in Smokers With and Without Schizophrenia | June 2013 | May 2015 |
| NCT03418831 | Completed | Phase 4 | Adjunctive Selective Estrogen Receptor Modulators on Negative and Cognitive Symptoms of Schizophrenia in Women | July 17, 2018 | July 30, 2019 |
| NCT00446992 | Completed | Phase 1/Phase 2 | Diabetes in Neuropsychiatric Disorders | April 2006 | March 2010 |
| NCT00423878 | Completed | Phase 4 | Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder | January 2007 | March 2010 |
| NCT01036568 | Completed | Neuroimaging Studies of Neurophysiological Phenotypes in Schizophrenia | February 14, 2006 | March 7, 2013 | |
| NCT01999309 | Completed | Phase 3 | Simvastatin Addition for Patients With Recent-onset Schizophrenia | October 2013 | December 19, 2019 |
| NCT00963846 | Completed | Phase 2 | Huperzine for Cognitive and Functional Impairment in Schizophrenia | March 2010 | December 2012 |
| NCT01569659 | Completed | Phase 4 | High Dose Lurasidone for Patients With Treatment Resistant Schizophrenia | October 2011 | July 2015 |
| NCT01457339 | Completed | Phase 1 | Assess the Safety and Pharmacokinetics of Ascending, Multiple Oral Doses of SPD489 in Adults With Schizophrenia | October 21, 2011 | January 20, 2012 |
| NCT04598906 | Completed | N/A | Ecologically Valid Virtual Tasks vs Paper-pencil Methods in Cognitive Rehabilitation in Patients With Schizophrenia and Depression | September 1, 2019 | January 1, 2021 |
| NCT03671525 | Completed | Early Phase 1 | Cognitive Effects of Nimodipine in Patients With Schizophrenia | October 5, 2018 | May 12, 2023 |
| NCT01626456 | Completed | Phase 3 | A Long-term Safety Study of ALKS 9072 (Also Known as ALKS 9070) | June 2012 | April 2015 |
| NCT00307216 | Completed | N/A | Graduated Recovery Intervention Program for Enhancing Treatment for First-Episode Psychosis | April 2006 | December 2008 |
| NCT00963924 | Completed | N/A | D-cycloserine Augmentation of Cognitive Remediation in Schizophrenia | August 2009 | June 2011 |
| NCT01646827 | Completed | Phase 1 | An Open Label Study of Aripiprazole Intramuscular Injection in Subjects With Schizophrenia | May 2012 | April 2013 |
| NCT01940939 | Completed | N/A | Study of Repetitive Transcranial Magnetic Stimulation in the Treatment of Cognitive Impairment in Schizophrenia | February 1, 2013 | January 31, 2015 |
| NCT01310998 | Completed | N/A | Acute Psychological Effects of High Intensity Exercise With Schizophrenia | December 2010 | June 2011 |
| NCT00338598 | Completed | Phase 2 | Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism | June 2003 | December 2015 |
| NCT02453217 | Completed | N/A | The Potential Efficacy of the Chinese Health Improvement Profile- A Pilot Clustered Randomised Controlled Trial | March 31, 2016 | January 31, 2019 |
| NCT01496690 | Completed | Phase 4 | Pregablin for Anxiety-comorbidity in Patients With Schizophrenia | January 2012 | December 2016 |
| NCT00288340 | Completed | N/A | Quantifying Abnormalities in Cortical Activation Associated With Auditory Hallucinations Using Functional Magnetic Resonance Imaging | January 2006 | August 2006 |
| NCT02199743 | Completed | Phase 4 | Lurasidone Effects on Tissue Glutamate in Schizophrenia | February 2013 | June 2016 |
| NCT05053451 | Completed | N/A | Brain Stimulation, Clinical Symptoms and Cognition | September 14, 2021 | April 10, 2024 |
| NCT02006862 | Completed | eVAluatIon of OLanzapine TreatmEnT | January 2014 | December 2014 | |
| NCT01641900 | Completed | N/A | Effects of Eszopiclone on Sleep and Memory in Schizophrenia | July 2012 | December 2015 |
| NCT04190004 | Completed | N/A | Effect of Intranasal Vasopressin on Cooperative Behavior in Schizophrenia | January 1, 2018 | November 30, 2018 |
| NCT01495741 | Completed | Post-Authorization Safety Surveillance Study of Asenapine in Participants With Bipolar Disorder (P08307) | July 1, 2013 | December 18, 2017 | |
| NCT00694707 | Completed | Phase 2 | Safety and Efficacy of Cariprazine (RGH-188) in the Acute Exacerbation of Schizophrenia | June 30, 2008 | August 31, 2009 |
| NCT00653406 | Completed | Phase 1/Phase 2 | A Pharmacokinetic and Safety Study of Risperidone Long Acting Injectable in Schizophrenic Patients | November 2002 | October 2003 |
| NCT00986531 | Completed | Phase 1 | The Effects AZD8529 on Cognition and Negative Symptoms in Schizophrenics | November 2009 | October 2011 |
| NCT00558298 | Completed | Phase 3 | A Long Term Study of Safety for Long Acting Injectable Risperidone in Patients With Schizophrenia or Schizoaffective Disorder. | February 2000 | February 2005 |
| NCT00481156 | Completed | Phase 3 | Functional Neuroimaging Effects of Cognitive Remediation Training | March 1, 2005 | February 28, 2007 |
| NCT00833547 | Completed | N/A | Effects of Eszopiclone on Sleep-dependent Learning in Schizophrenia | September 2006 | September 2012 |
| NCT00460512 | Completed | Phase 3 | An Efficacy, Safety And Tolerability Study of Flexibly Dosed Paliperidone Extended Release (ER) in Participants With Schizophrenia | April 25, 2007 | March 4, 2020 |
| NCT00796081 | Completed | Phase 1 | A Safety and Pharmacokinetic Study of ER OROS Paliperidone in Pediatric Patients With Schizophrenia, Schizoaffective Disorder, or Schizophreniform Disorder | January 2006 | August 2006 |
| NCT01074073 | Completed | Phase 1 | Lithium Drug-Drug Interaction Study With Lurasidone HCl | August 2008 | October 2008 |
| NCT02694328 | Completed | Phase 3 | A Study of ALKS 3831 in Adults With Schizophrenia (The ENLIGHTEN-2 Study) | March 2, 2016 | November 7, 2018 |
| NCT00565175 | Completed | Phase 4 | Histamine H2 Antagonism as Adjuvant Therapy in Treatment Resistant Schizophrenia | January 2008 | December 2011 |
| NCT01626859 | Completed | Phase 2/Phase 3 | A Pharmacokinetic Study of MP-214 in Patients With Schizophrenia | May 2012 | August 2013 |
| NCT00736710 | Completed | N/A | rTMS Effects on Smoking Cessation and Cognition in Schizophrenia | December 2008 | May 2011 |
| NCT00425399 | Completed | N/A | Shiatsu Adjuvant Therapy For Schizophrenia | January 2007 | June 2008 |
| NCT00791232 | Completed | Phase 1 | A Study of Extended Release Extended-release (ER) OROS Paliperidone Tolerability, as Compared to Immediate-release (IR)Risperidone, in Patients With Schizophrenia | March 2003 | June 2003 |
| NCT03504579 | Completed | N/A | Rt-fMRI Neurofeedback and AH in Schizophrenia | March 1, 2018 | June 30, 2022 |
| NCT02331433 | Completed | Phase 1 | Safety, Tolerability, and Pharmacokinetics of Single Doses of APN1125 in Healthy Normal Subjects | December 2014 | December 2015 |
| NCT00594256 | Completed | Phase 2 | Sodium Oxybate in Schizophrenia With Insomnia | May 2008 | April 2009 |
| NCT04590300 | Completed | N/A | Impact of Cognitive & Metacognitive Performance on Knowledge Learning When Conducting Therapeutic Education Programs | October 6, 2020 | December 31, 2022 |
| NCT00705783 | Completed | Phase 3 | Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia | July 2008 | February 2011 |
| NCT00155701 | Completed | Mutation Screening and Translocation Detection of DISC1 Gene in Schizophrenia | August 2002 | July 2003 | |
| NCT01884025 | Completed | N/A | Get Moving and Get Well - Pilot Study | June 2013 | August 2015 |
| NCT00179231 | Completed | N/A | Olanzapine Versus Clozapine in Treatment Refractory Schizophrenia | May 2000 | February 2004 |
| NCT00481026 | Completed | N/A | A Double Blind Sham Controlled Trial of tDCS in Treating Schizophrenia and Depression | August 2007 | May 2013 |
| NCT00783120 | Completed | N/A | Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Negative Symptoms in Schizophrenia | January 2008 | December 2011 |
| NCT00350883 | Completed | Phase 2 | Cognitive Therapy for Negative Symptoms and Functioning | July 2006 | November 2011 |
| NCT00791167 | Completed | Phase 1 | A Study of the Dose Proportionality of Extended Release Paliperidone | June 2006 | August 2006 |
| NCT01165294 | Completed | Phase 1 | The Effect of Ketamine on Attentiveness | October 2009 | May 2010 |
| NCT00012961 | Completed | Improving Health Services for Veterans With Schizophrenia | March 2003 | ||
| NCT01682161 | Completed | Phase 4 | A Comparative Study to Evaluate the Evolution of Medication Satisfaction and Adherence in Patients Unsatisfied With Current Oral Atypical Antipsychotics by Switching Medication to Paliperidone Palmitate | January 2012 | September 2013 |
| NCT00246194 | Completed | Observational Study in Patients With Schizophrenia Treated With Long-Acting Risperidone Injection (RISPERDAL CONSTA) | September 2004 | November 2007 | |
| NCT03751280 | Completed | Phase 2 | Study of Efficacy of PEAR-004 in Schizophrenia | December 10, 2018 | September 26, 2019 |
| NCT00287352 | Completed | Phase 1 | Study of Amantadine for Weight Stabilization During Olanzapine Treatment | May 2005 | September 2009 |
| NCT06372210 | Completed | N/A | A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion | June 26, 2023 | July 19, 2023 |
| NCT00531518 | Completed | N/A | Early Detection and Intervention for the Prevention of Psychosis | October 2007 | September 2013 |
| NCT02970292 | Completed | Phase 3 | Efficacy and Safety of Adjunctive Pimavanserin for the Treatment of Schizophrenia (ENHANCE-1) | October 26, 2016 | June 25, 2019 |
| NCT02787122 | Completed | N/A | Pilot-trial of Emotion-focused Cognitive Behavior Therapy for Patients With Schizophrenia | January 1, 2014 | December 31, 2017 |
| NCT03775564 | Completed | N/A | Effectiveness of the RemedRugby Program | November 2014 | December 2018 |
| NCT00463879 | Completed | Phase 2/Phase 3 | Galantamine for Cognitive Deficits in Schizophrenia | September 2005 | September 2007 |
| NCT01746134 | Completed | The Management of Schizophrenia in Clinical Practice (MOSAIC) | December 2012 | May 2014 | |
| NCT04191200 | Completed | Oral Status of Patients Suffering From SCHIZophrenia Followed at Charles Perrens Hospital | September 24, 2019 | December 31, 2019 | |
| NCT04118127 | Completed | Phase 1 | A Clinical Pharmacology Trial of Brexpiprazole Once-weekly (QW) Formulation Administered as Single and Multiple Oral Doses | October 17, 2019 | March 3, 2021 |
| NCT03711500 | Completed | Phase 1/Phase 2 | D-serine Augmentation of Neuroplasticity | March 13, 2019 | April 30, 2021 |
| NCT01149577 | Completed | Phase 4 | Effect of Olanzapine on Sleep Electroencephalogram (EEG) in Schizophrenia Patients | August 2007 | April 2009 |
| NCT04306146 | Completed | Phase 1 | Study of CAD-9303 in Subjects With Schizophrenia | February 28, 2020 | November 24, 2021 |
| NCT00172731 | Completed | Measurement of Activity Participation for Persons With Schizophrenia Living in the Community | March 2005 | June 2005 | |
| NCT00156104 | Completed | Phase 3 | Efficacy and Safety of Asenapine With Placebo and Haloperidol (41023)(P05926)(COMPLETED) | July 1, 2005 | September 16, 2006 |
| NCT00086320 | Completed | Phase 3 | A Study of Effectiveness and Safety of Paliperidone Extended-release (ER) Tablets in the Prevention of Recurrence in Adult Patients With Schizophrenia. | March 2004 | August 2005 |
| NCT02730832 | Completed | N/A | Validation of a Scale to Evaluate the Perception of Oral Health in Patients With Schizophrenia | June 20, 2016 | April 19, 2017 |
| NCT05304780 | Completed | N/A | Needs-tailored Nurse-led Recovery Program for Community-dwelling People With Schizophrenia | July 15, 2020 | December 31, 2021 |
| NCT04874974 | Completed | N/A | Feasibility of a Novel Process-based Treatment for Patients With Psychosis | May 10, 2021 | September 23, 2023 |
| NCT00655239 | Completed | N/A | Effectiveness of Neuroadaptive Cognitive Training in Adolescents at Risk for Psychosis | June 2008 | May 2016 |
| NCT02712463 | Completed | A Study to Assess the Rate of Hospitalization in Participants With Schizophrenia Treated With Antipsychotics | July 2015 | April 2016 | |
| NCT04659161 | Completed | Phase 3 | A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2) | December 16, 2020 | May 24, 2022 |
| NCT03863925 | Completed | Phase 4 | Comparison of Propofol Target-Controlled Infusion Anesthesia and Bolus Injection in Electroconvulsive Therapy | August 15, 2017 | February 2, 2019 |
| NCT04602741 | Completed | N/A | Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-management and Provider Engagement | January 4, 2021 | June 1, 2023 |
| NCT00827918 | Completed | Phase 2 | A Study to Test the Safety and Efficacy of MK-8998 in Acutely Psychotic Participants With Schizophrenia (MK-8998-004) | March 2009 | April 2010 |
| NCT00239122 | Completed | N/A | Recovery Therapy Trial | June 2000 | February 2004 |
| NCT00177580 | Completed | Phase 4 | Improving Symptoms of Schizophrenia and Schizoaffective Disorder by Supplementing Medications With Pravastatin | July 2003 | July 2007 |
| NCT00053703 | Completed | Phase 4 | Treatment of Early Onset Schizophrenia Spectrum Disorders (TEOSS) | February 2002 | May 2007 |
| NCT01378078 | Completed | N/A | Transcranial Direct Current Stimulation (tDCS) for Treatment of Negative Syndrome in Patients With Schizophrenia | June 2011 | June 2013 |
| NCT01639872 | Completed | Phase 4 | Clozapine for Cannabis Use in Schizophrenia | May 1, 2013 | March 29, 2017 |
| NCT01674543 | Completed | N/A | Clinical Symptoms of Schizophrenia and Physical Exercise | February 2010 | March 2013 |
| NCT00718510 | Completed | N/A | L-arginine in Treatment as Usual in Schizophrenia | September 2009 | October 2012 |
| NCT00631722 | Completed | N/A | Multicenter, Open-Label, Randomised, Haloperidol-controlled Study to Evaluate Seroquel as Mono-Therapy in the Treatment of Agitated Symptoms in the Patients With Acute Episode of Schizophrenia | May 2007 | May 2008 |
| NCT00753506 | Completed | N/A | Artemisinin to Reduce The Symptoms of Schizophrenia | August 2008 | May 2010 |
| NCT01376492 | Completed | FYS Study: Epidemiological, Multicentre, Cross-sectional Study in a Clinical Practice Environment, About the Relationship Between Functioning Status and the Quality of Sleep Perceived by Schizophrenic Outpatients in Spain | November 2010 | July 2011 | |
| NCT00573287 | Completed | N/A | First Episode Schizophrenia and Cannabis-Related Disorder Study | June 2006 | December 2011 |
| NCT01892384 | Completed | Phase 1 | Safety and Tolerability of BI 409306 in Patients With Schizophrenia | June 28, 2013 | December 5, 2013 |
| NCT02332798 | Completed | Phase 1 | Multiple Ascending Doses of PF-04958242 in Subjects With Stable Schizophrenia | January 6, 2015 | April 15, 2015 |
| NCT00423943 | Completed | Phase 4 | Modafinil for Treatment of Cognitive Dysfunction in Schizophrenia | September 2005 | December 2012 |
| NCT01879722 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetic Study of Multiple Rising Doses of TAK- 063 in Participants With Stable Schizophrenia and Healthy Participants | June 2013 | June 2014 |
| NCT00174200 | Completed | N/A | Study To Assess Differential Sensitivity Of 2 Spatial Working Memory Tests In Schizophrenics Treated With Risperidone | December 2004 | May 2006 |
| NCT00895258 | Completed | Phase 2 | Cognitive Training to Improve Work Outcomes in Severe Mental Illness | April 2008 | March 2014 |
| NCT00212784 | Completed | Phase 3 | Efficacy and Safety of Asenapine Using an Active Control in Subjects With Schizophrenia or Schizoaffective Disorder (25517)(P05935) | September 4, 2003 | March 15, 2006 |
| NCT00640601 | Completed | Phase 3 | Study Evaluating the Clinical Benefit of SEROQUEL XR in Subjects With Schizophrenia | March 2008 | July 2010 |
| NCT01298349 | Completed | Perception Processing in Schizophrenia Patients and Normal Population | February 2011 | December 2017 | |
| NCT01724359 | Completed | Phase 4 | Tolerability, Safety and Efficacy of Flexibly Dosed Paliperidone ER in Patients With Schizophrenia | February 2008 | November 2009 |
| NCT00208169 | Completed | Phase 4 | Abilify Therapy for Reducing Comorbid Substance Abuse | March 2005 | June 2007 |
| NCT01222793 | Completed | Effects of Antipsychotics on Eating and Food Craving in People With Schizophrenia | September 26, 2010 | May 3, 2012 | |
| NCT01284959 | Completed | Phase 4 | Different Safety Profile of Risperidone and Paliperidone Extended-release | June 2010 | December 2010 |
| NCT00798109 | Completed | N/A | Effect of Motivational Therapy on Schizophrenia With Cannabis Misuse | November 2008 | April 2013 |
| NCT00191555 | Completed | Phase 4 | Efficacy Study of Switching Stabilized Schizophrenic Patients From Conventional to Atypical Antipsychotic Treatment | August 2003 | May 2006 |
| NCT02360566 | Completed | N/A | Participatory Video as a Recovery-Oriented Intervention in Early Psychosis | January 2016 | December 2016 |
| NCT01515423 | Completed | Phase 3 | Study of Paliperidone Palmitate 3 Month and 1 Month Formulations for the Treatment of Patients With Schizophrenia | May 2012 | March 2015 |
| NCT04495998 | Completed | N/A | The Motor Neurological Soft Signs (MNSS) in Persons With Schizophrenia | January 2017 | June 2020 |
| NCT01754532 | Completed | Correlation Between Clinical Deterioration in Schizophrenic Patients and Hair Cortisol Levels | January 2013 | January 2016 | |
| NCT02085447 | Completed | N/A | A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness | May 2014 | December 2016 |
| NCT00088634 | Completed | Phase 2 | A Study to Test the Effectiveness and Safety of a New Medication in the Treatment of Schizophrenia | May 2004 | December 2004 |
| NCT00861796 | Completed | Phase 2 | Study of CYR-101 in Patients With Schizophrenia | March 2008 | June 2010 |
| NCT05835583 | Completed | N/A | Theory Based Integrated Program on Medication Adherence Among Community Dwelling Schizophrenia | August 1, 2021 | December 1, 2022 |
| NCT00159120 | Completed | Phase 4 | Maintenance Treatment vs. Stepwise Drug Discontinuation in First-Episode Schizophrenia | November 2001 | June 2006 |
| NCT05011669 | Completed | Phase 4 | The Safety and Efficacy of Lurasidone With Different Initiation Dose in Chinese Acute Phase Patients With Schizophrenia | August 16, 2021 | June 16, 2023 |
| NCT01003379 | Completed | Phase 2 | TC-5619 as Augmentation Therapy to Improve Cognition in Outpatients With Cognitive Dysfunction in Schizophrenia | October 2009 | December 2010 |
| NCT00137280 | Completed | N/A | Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2) | June 13, 2007 | May 31, 2011 |
| NCT00957294 | Completed | Metabolic Syndrome in Patients With First-episode Schizophrenia | August 2009 | April 2013 | |
| NCT00373126 | Completed | Phase 4 | The Effects of Nicotine Withdrawal on Reward Responsivity in Schizophrenia | April 2005 | |
| NCT00337662 | Completed | Phase 4 | Efficacy Study of Early Onset of Antipsychotic Drug Action in Schizophrenia | May 2006 | December 2007 |
| NCT01452919 | Completed | Phase 3 | A Physical Dependence Study in Schizophrenia | November 2011 | September 2012 |
| NCT01547026 | Completed | N/A | Self-regulation Strategies to Improve Exercise Behavior Among Schizophrenic Patients | April 2012 | December 2012 |
| NCT01518894 | Completed | Phase 1 | A Study To Examine The Safety, Tolerability And Pharmacokinetics Of PF-04958242 In Psychiatrically Stable Subjects With Schizophrenia | November 2011 | March 2012 |
| NCT02442817 | Completed | Phase 4 | Linagliptin and Mesenchymal Stem Cells: A Pilot Study | March 2, 2015 | March 2, 2018 |
| NCT02055287 | Completed | Phase 1 | Pharmacokinetic and Safety Study of LY03004 in Stable Patients With Schizophrenia or Schizoaffective Disorder | March 2013 | June 2014 |
| NCT01077687 | Completed | Expanding Rapid Ascertainment Networks of Schizophrenia Families in Taiwan | July 2009 | December 2013 | |
| NCT01521026 | Completed | N/A | Cognitive Training for Patients With Schizophrenia | September 2003 | August 2009 |
| NCT00227305 | Completed | Phase 3 | Quetiapine Fumarate (SEROQUEL) in the Treatment of Adolescent Patients With Schizophrenia and Bipolar I Disorder | August 2004 | December 2007 |
| NCT02660775 | Completed | N/A | Social Cognitive Assessment in Autism and Schizophrenia | December 4, 2015 | June 30, 2021 |
| NCT00727103 | Completed | Phase 4 | Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia | July 2008 | May 2011 |
| NCT00222794 | Completed | Phase 4 | A Clinical Trial to Examine Effects of Atomoxetine in the Treatment of Negative Symptoms in Patients With Schizophrenia | November 2003 | July 2006 |
| NCT00534222 | Completed | Unraveling the Relation of Patient's Profile and Therapeutical Effects of Atypicals, Including Quetiapine Effect | September 2005 | December 2007 | |
| NCT01312272 | Completed | N/A | Does Acute Oxytocin Administration Enhance Social Cognition in Individuals With Schizophrenia? | April 2011 | August 2012 |
| NCT00921362 | Completed | Seroquel (Quetiapine Fumarate) InPractice Evaluation Programme | May 2006 | January 2007 | |
| NCT00645502 | Completed | Phase 1 | Bioequivalence Study Comparing 2 Formulations for 4 mg Risperidone Tablet. | June 2003 | July 2003 |
| NCT00333970 | Completed | N/A | Predictors of Response to Cognitive Remediation in Schizophrenia | August 2004 | July 2014 |
| NCT01291511 | Completed | Phase 3 | Relapse Prevention Study in Patients With Schizophrenia | February 2011 | March 2015 |
| NCT00229385 | Completed | N/A | Treatment With Ziprasidone for Schizophrenia Patients With Obsessive Compulsive Disorder (OCD) | January 2006 | April 2010 |
| NCT03730857 | Completed | Phase 1 | Early Predictors of Poor Treatment Response in Patients With Schizophrenia Treated With Atypical Antipsychotics | January 2008 | December 2008 |
| NCT00085748 | Completed | Phase 3 | Safety Study With Paliperidone ER Extended-Release (ER) Tablets in Geriatric Patients With Schizophrenia | August 2004 | May 2005 |
| NCT01992393 | Completed | N/A | Targeted Self-Management for Epilepsy and Serious Mental Illness (TIME) | September 2013 | September 2015 |
| NCT00303602 | Completed | Phase 4 | Comparing the Effect of Under the Tongue Olanzapine Versus Swallowed Olanzapine on Body Mass Index (A Ratio of Weight to Height) | March 2006 | December 2007 |
| NCT00396643 | Completed | Phase 4 | Indicated Prevention With Omega-3 Fatty Acids in Adolescents With 'At-Risk-Mental-State' for Psychosis | May 2004 | June 2007 |
| NCT00919607 | Completed | Phase 1 | Evaluate the Pharmacokinetics of Quetiapine Fumarate in Chinese Schizophrenic Patients | June 2009 | March 2010 |
| NCT00063336 | Completed | N/A | Treatment Response to Rehabilitation in Patients With Schizophrenia | December 2001 | November 2005 |
| NCT02831231 | Completed | Phase 1 | Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium | September 7, 2016 | October 28, 2016 |
| NCT02246283 | Completed | Schizophrenia for "Life" - a Registry and Interview Study Among Elderly With Lifelong Schizophrenia | September 2013 | December 2017 | |
| NCT00247637 | Completed | The Genetic Basis of Inherited Neurologic Deficits in People With Schizophrenia | May 2003 | September 2008 | |
| NCT00249223 | Completed | Phase 3 | A Comparison of the Effectiveness and Safety of Injectable Risperidone With That of Risperidone Tablets in the Treatment of Patients With Chronic Schizophrenia | January 2000 | December 2000 |
| NCT00458094 | Completed | N/A | Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses | March 2007 | December 2009 |
| NCT04783285 | Completed | N/A | Effect of Individual Cognitive Stimulation at Home in Adults With Psychotic Disorders | March 29, 2021 | December 31, 2021 |
| NCT01431326 | Completed | Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care | November 2011 | November 2019 | |
| NCT01312649 | Completed | N/A | Feeling of Being in Control of One's Own Action | April 2011 | June 15, 2017 |
| NCT02237235 | Completed | Phase 2 | Effect of MMFS-202-302 on Cognitive Enhancement in Schizophrenia | August 2014 | August 2017 |
| NCT01942148 | Completed | Phase 3 | A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Schizophrenia | August 2010 | November 2015 |
| NCT00559572 | Completed | N/A | Effects of Motivating People With Schizophrenia to Exercise | November 2007 | August 2009 |
| NCT01945333 | Completed | N/A | Personalized and Scalable Cognitive Remediation Approaches | September 2013 | March 20, 2019 |
| NCT00654706 | Completed | Phase 3 | Efficacy Study Exploring the Effects on Cognition of Sertindole Versus Comparator in Patients With Schizophrenia | March 2008 | March 2010 |
| NCT00001258 | Completed | Studies of Frontal Lobe Brain Functioning in Schizophrenia | November 26, 1993 | ||
| NCT00214578 | Completed | Phase 4 | Seroquel on Glucose Metabolism | April 2004 | October 2005 |
| NCT02118571 | Completed | Schizophrenia Cognition Scale Development | November 2013 | July 2016 | |
| NCT00316303 | Completed | Phase 2 | Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder | February 2006 | August 2012 |
| NCT02535676 | Completed | Phase 3 | Schizophrenia TreAtment With electRic Transcranial Stimulation | November 2014 | May 2018 |
| NCT00538642 | Completed | N/A | Improving Diabetes Risk Factors in Persons With Schizophrenia or Bipolar Disorder by Switching to Ziprasidone | August 2007 | November 2011 |
| NCT00338949 | Completed | Phase 4 | Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes | June 2006 | December 2009 |
| NCT01607840 | Completed | N/A | Effects of Transcranial Direct Current Stimulation in Individuals With Schizophrenia | June 2012 | September 2014 |
| NCT00995553 | Completed | N/A | Remediation of Working Memory in Schizophrenia | January 2010 | December 2015 |
| NCT01429740 | Completed | Phase 1 | A Study Of The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-05180999 In Healthy Adults | August 2011 | December 2011 |
| NCT02474524 | Completed | N/A | Self-Management and Recovery Technology Psychosocial Intervention Trial | January 1, 2015 | July 2017 |
| NCT02339844 | Completed | Phase 4 | Pan European Collaboration on Antipsychotic Naïve Schizophrenia II | January 2014 | January 2021 |
| NCT04578314 | Completed | N/A | RELATE - Efficacy and Feasibility of a Cognitive Behavioural Module for Distressing Auditory Verbal Hallucinations | October 1, 2020 | January 29, 2023 |
| NCT02704962 | Completed | Phase 4 | Olanzapine vs. Low-dose Olanzapine Plus Trifluoperazine | January 2012 | February 2016 |
| NCT02911519 | Completed | N/A | Brief Group Psychoeducation for Schizophrenia | August 1, 2013 | February 24, 2017 |
| NCT01577186 | Completed | Phase 4 | Symptomatic Remission and Social Function in Participants Treated With Paliperidone Extended Release (ER) | July 2008 | June 2009 |
| NCT04024371 | Completed | Validating Reward-related Biomarkers (RTOC) | September 16, 2019 | February 1, 2021 | |
| NCT02589262 | Completed | Phase 1 | Safety, Blood Levels and Effects of AUT00206 | September 2015 | July 2016 |
| NCT01975584 | Completed | N/A | Neuroendocrine and Immune Response to Stress in Schizophrenia | September 2013 | June 2018 |
| NCT01010477 | Completed | Phase 4 | Trial of Nicotine Nasal Spray as an Aid for Smoking Cessation in Schizophrenia | August 2009 | August 2012 |
| NCT00101569 | Completed | Phase 3 | Aripiprazole Oral Acceptability Trial | March 2004 | March 2005 |
| NCT00838123 | Completed | Cognitive Functioning Related to Job Tenure Among Patients With Schizophrenia | August 2008 | December 2008 | |
| NCT00257023 | Completed | Phase 2 | An Exploratory Study on the Safety and Effectiveness of Paliperidone in Patients With Schizophrenia | February 2005 | September 2005 |
| NCT02869334 | Completed | N/A | Remediation of Auditory Recognition in Schizophrenia With tDCS | June 2016 | January 31, 2020 |
| NCT01377896 | Completed | The Purpose of the Study is to Gain an In-depth Picture of the Patient Management and Prescription Behaviours | July 2010 | October 2010 | |
| NCT00261716 | Completed | Phase 3 | Motivational Interviewing to Improve Work Outcomes in Schizophrenia | January 2005 | February 2010 |
| NCT01447082 | Completed | General Practice Research Database Seroquel XR Safety Study | October 2008 | December 2012 | |
| NCT00538122 | Completed | Changes in Heart Rhythms Associated With Antipsychotic Drug Treatment | July 2007 | September 2008 | |
| NCT00510211 | Completed | An Observational Study of Olanzapine Coated and Orodispersible Tablets Effectiveness in Schizophrenic and Bipolar Outpatients. | April 2007 | May 2009 | |
| NCT01422902 | Completed | Phase 2 | Evaluation of a Cognitive Adaptive E-treatment in Schizophrenia-diagnosed Adults | April 2012 | June 2015 |
| NCT00377117 | Completed | Diabetes Screening, Risk Management and Disease Management in a High-Risk Mental Health Population Part II | May 2006 | July 2007 | |
| NCT05257720 | Completed | Evaluation of the Role of Neurodegeneration in Schizophrenia | March 28, 2022 | October 1, 2022 | |
| NCT02736474 | Completed | Phase 4 | Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia | May 2016 | July 2018 |
| NCT02864576 | Completed | N/A | Cognitive Remediation Plus Aerobic Exercise in Schizophrenia Treatment | September 2016 | December 2020 |
| NCT00356317 | Completed | Phase 2 | Culturally Based Family Therapy for Improving Treatment Outcome for People With Schizophrenia | March 2015 | March 2015 |
| NCT01214005 | Completed | Phase 2 | Smoking Abstinence and Lapse Effects in Smokers With Schizophrenia and Controls | June 2009 | February 2012 |
| NCT01411085 | Completed | Phase 2 | Risperidone and Desipramine in Alcohol Use and Schizophrenia | December 2011 | September 2014 |
| NCT04511663 | Completed | N/A | The Effectiveness of Assertive Community Treatment on Schizophrenic Patients | July 1, 2017 | December 31, 2019 |
| NCT01895452 | Completed | Phase 3 | An Extension of a Long-term Safety Study of ALKS 9072 (Also Known as ALKS 9070) | July 2013 | June 2016 |
| NCT00686998 | Completed | Phase 2 | Phase IIA Study in Patients With Schizophrenia | May 2008 | March 2009 |
| NCT02675530 | Completed | Phase 1 | Parallel Effects of Schizophrenia and N-methyl-D-aspartate (NMDA) Antagonism | December 2007 | December 2011 |
| NCT03485339 | Completed | Substance Misuse To Psychosis for Ketamine (SToP-K) | June 12, 2018 | April 1, 2020 | |
| NCT00225498 | Completed | N/A | Neurocognitive Effects of Ziprasidone: Relationship to Working Memory and Dopamine Blockade | June 2002 | October 2008 |
| NCT01052389 | Completed | Phase 4 | Pragmatic RCT Comparing Aripiprazole, Olanzapine and Haloperidol in the Treatment of Schizophrenia | July 2007 | June 2013 |
| NCT01381419 | Completed | Phase 1 | First Time in Human Study (FTIH) With Positron Emission Tomography (PET) | October 20, 2008 | April 1, 2009 |
| NCT02307396 | Completed | Phase 4 | Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients | February 1, 2015 | June 22, 2016 |
| NCT02451371 | Completed | Phase 1/Phase 2 | Treatment of Refractory Auditory Verbal Hallucinations With tDCS in Schizophrenia | August 2016 | December 2016 |
| NCT02260830 | Completed | Phase 1 | Pharmacokinetic Properties of Various Modified Release Tablet Formulations of Lu AF11167 | August 2014 | |
| NCT01730768 | Completed | Phase 2 | A Study to Evaluate the Effects of Once Daily Doses of AQW051 on Cognition, in Stable Schizophrenia Patients | September 2012 | December 2013 |
| NCT00345982 | Completed | N/A | Augmenting Clozapine With Sertindole - SERCLOZ | September 2006 | September 2010 |
| NCT02678858 | Completed | N/A | Efficacy of ISST in Schizophrenia | March 2016 | March 2022 |
| NCT00772005 | Completed | Phase 2 | Study to Evaluate the Efficacy and Safety of Armodafinil as Adjunctive Therapy in Adults With Schizophrenia | September 2008 | May 2010 |
| NCT01339858 | Completed | Phase 4 | The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage Schizophrenia | May 2011 | December 2015 |
| NCT01136772 | Completed | Phase 4 | A Comparison of Long-acting Injectable Medications for Schizophrenia | March 2011 | July 2016 |
| NCT03386851 | Completed | Abilify Maintena PMS in Schizophrenia Patients or Bipolar 1 Disorder | December 13, 2016 | May 25, 2021 | |
| NCT00237874 | Completed | Phase 2/Phase 3 | Aripiprazole Treatment of Prodromal Patients | February 2004 | February 2007 |
| NCT00644800 | Completed | Phase 4 | A Study of the Efficacy and Safety of Intramuscular Ziprasidone Followed by Oral Ziprasidone for the Treatment of Psychosis | July 2003 | May 2004 |
| NCT00882518 | Completed | Phase 3 | Efficacy and Safety of Quetiapine Fumarate in the Treatment of Schizophrenic Patients | April 2009 | July 2010 |
| NCT00411866 | Completed | Phase 1 | Effects Of The Drug Ketoconazole On How The Body Handles The Drug SB773812 | October 13, 2006 | October 10, 2007 |
| NCT01809158 | Completed | Phase 4 | Minocycline for Schizophrenia | April 2013 | June 2016 |
| NCT02453763 | Completed | In Vivo Imaging of Therapeutic Electric Current Flow | June 2015 | July 6, 2017 | |
| NCT01390376 | Completed | Phase 2 | DAAOI-1 Treatment for Treatment-resistant Schizophrenia | September 2010 | September 2014 |
| NCT01092598 | Completed | Factors Association With Poor Physical Function in Older Adults With Schizophrenia | March 2010 | May 2015 | |
| NCT00156065 | Completed | Phase 3 | Long-Term Efficacy and Safety of Asenapine Using Haloperidol as a Positive Control (41513)(COMPLETED)(P05785) | September 2005 | October 2007 |
| NCT00190749 | Completed | Phase 4 | Safety Study of Olanzapine and a Comparator in Patients With Schizophrenia and Schizoaffective Disorder | October 2003 | June 2008 |
| NCT03201757 | Completed | Phase 3 | Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831 | June 15, 2017 | September 6, 2023 |
| NCT03178279 | Completed | N/A | The Evaluation of the Use of a New Physical Health Plan | December 6, 2017 | September 30, 2019 |
| NCT04659174 | Completed | Phase 3 | An Extension Study to Assess Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-4) | February 1, 2021 | October 3, 2023 |
| NCT02354001 | Completed | Phase 4 | Selective Estrogen Receptor Modulators for Women of Child-bearing Age With Schizophrenia | April 2011 | January 2019 |
| NCT00001768 | Completed | Phase 3 | Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg) | October 1997 | June 2000 |
| NCT00628420 | Completed | Phase 1 | Safety Study of ACP-104: To Demonstrate the Safety, Tolerability, and Pharmacokinetics | January 2005 | October 2007 |
| NCT01953237 | Completed | N/A | MedActive: A Smartphone Intervention to Improve Adherence to Antipsychotic Medications | September 2013 | December 2015 |
| NCT06136936 | Completed | N/A | A Study to Evaluate the Overall Effects of Treatment With Abbreviated CT-156 in People With Schizophrenia | September 20, 2023 | February 22, 2024 |
| NCT00153959 | Completed | N/A | Psychiatric Day Hospital Treatment | ||
| NCT01578486 | Completed | Phase 4 | Salsalate as an Adjunctive Treatment for Patients With Schizophrenia | June 2011 | July 2015 |
| NCT02896374 | Completed | N/A | Normal and Abnormal ERP During ToM and Emotional Conflicts in Schizophrenia | March 2013 | December 2017 |
| NCT00821600 | Completed | Phase 1 | Characterization of Intramuscular Injections of Risperidone 4 Week Long-acting Injectable (LAI) Formulation in the Buttock of Patients With Schizophrenia | December 2008 | June 2009 |
| NCT01433055 | Completed | N/A | Adjunctive Minocycline in Clozapine Treated Schizophrenia Patients | July 2011 | January 2014 |
| NCT00493233 | Completed | N/A | Antipsychotic Polypharmacy in Schizophrenia | November 2006 | |
| NCT03891186 | Completed | N/A | Efficacy of Metacognitive Training for Schizophrenia - a Study Protocol | April 15, 2019 | April 4, 2020 |
| NCT04870996 | Completed | N/A | RCT of tDCS Combined With Cognitive Training in Schizophrenia | August 23, 2019 | June 30, 2020 |
| NCT04220099 | Completed | Electroencephalogram (EEG) and Electroconvulsive Therapy(ECT) Response in Schizophrenia | January 7, 2020 | July 4, 2020 | |
| NCT03346291 | Completed | N/A | Examining Persistence in Smokers With Schizophrenia | January 2017 | June 13, 2018 |
| NCT01795547 | Completed | Phase 3 | Aripiprazole Once-monthly Versus Paliperidone Palmitate in Adult Patients With Schizophrenia | February 2013 | September 2014 |
| NCT03872310 | Completed | N/A | Cognitive Enhancement on Working Memory in Patients With Schizophrenia | May 1, 2019 | August 30, 2021 |
| NCT04941677 | Completed | Exploring Hand Function in People With Schizophrenia Based on Perspective of Sensorimotor Control | September 17, 2020 | December 31, 2022 | |
| NCT00418171 | Completed | Phase 4 | Large Simple Trial (LST) Of Cardiovascular Safety Of Ziprasidone And Olanzapine- (Zodiac) | February 2002 | April 2007 |
| NCT00297388 | Completed | Phase 3 | A Study of How Long it Takes a Patient to Relapse After Switching From an Oral Antipsychotic to One of Two Doses of Long-acting Risperidone Injections in Patients With Schizophrenia or Schizoaffective Disorder | September 2004 | |
| NCT03079024 | Completed | N/A | Minnesota Community-Based Cognitive Training in Early Psychosis | May 19, 2017 | March 26, 2022 |
| NCT00178958 | Completed | N/A | Evaluation of QTc Interval by Continuous Holter ECG Recording in Antipsychotic Drug-treated Patients With Schizophrenia | August 2003 | June 2006 |
| NCT01160679 | Completed | Effectiveness of Atypical Antipsychotics on Anhedonic Features in Patients With Schizophrenia | August 2010 | August 2011 | |
| NCT00505973 | Completed | Phase 1 | Study Evaluating the Safety and Tolerability of SCA-136 in Healthy Japanese Male Subjects | July 2007 | October 2007 |
| NCT02188121 | Completed | Phase 4 | Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients | February 2015 | October 2021 |
| NCT00361543 | Completed | Phase 4 | Selective Estrogen Receptor Modulators - A Potential Treatment for Psychotic Symptoms of Schizophrenia | August 2006 | December 2014 |
| NCT02476877 | Completed | A Pilot, Proof-of-concept Cohort Study of the Prevalence of Comorbid Mental Illness and Substance Abuse | June 2014 | February 2016 | |
| NCT02936414 | Completed | N/A | Berberine Effect on Cytokine, CRP, Metabolic Disturbance as an Adjunctive Therapy in Schizophrenia Patients | July 2014 | December 2015 |
| NCT01714713 | Completed | Phase 3 | A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy | June 2013 | October 2015 |
| NCT00790192 | Completed | Phase 3 | Lurasidone HCL - A 6-week Phase 3 Study of Patients With Acute Schizophrenia. | October 2008 | July 2010 |
| NCT01129882 | Completed | Phase 3 | An Open-Label, Multicenter, Rollover, Long-term Study of Aripiprazole Intramuscular Depot in Participants With Schizophrenia | June 24, 2010 | December 6, 2018 |
| NCT00169702 | Completed | N/A | The Effect of a Weight Management Program During Treatment With Olanzapine | June 2003 | July 2007 |
| NCT01804257 | Completed | N/A | Event Marker Ingested To Trigger Event Recorder 3.0 Psychiatry Study | May 2010 | May 2011 |
| NCT00488319 | Completed | Phase 3 | Open-label Study of Flexible-dose Paliperidone ER (Extended Release) to Treat Adolescent Schizophrenia. | June 2007 | July 2012 |
| NCT01577160 | Completed | Phase 4 | A Study to Evaluate Flexible Dose of Paliperidone Extended Release (ER) and Clinical Response in Participants With Schizophrenia | May 2008 | April 2009 |
| NCT00930150 | Completed | Phase 4 | Feasibility of Providing Cognitive Remediation to People With Schizophrenia in a Clinical Network | July 2009 | February 2010 |
| NCT01885338 | Completed | Phase 1 | N-acetylcysteine (NAC) for Improving Cognitive Dysfunction in Schizophrenia | June 2013 | May 2014 |
| NCT06199817 | Completed | N/A | The Effect Of Multiple Occupational Therapies On Functional Remission And Subjective Recovery For Schizophrenia | June 1, 2016 | August 19, 2022 |
| NCT00358852 | Completed | Scale Validation Study for Prediction of Relapse and Short Term Rehospitalization in Patients With Schizophrenia | August 2006 | September 2008 | |
| NCT02950571 | Completed | N/A | RCT Examining the Effectiveness of Digital Picture Frame Use in Inpatient Setting | October 2016 | December 2017 |
| NCT01133587 | Completed | N/A | Patient Guided Psychiatric Admissions | May 2010 | December 2013 |
| NCT00338975 | Completed | N/A | Cognitive Behavioral Social Skills Training for Improving Social Functioning in People With Schizophrenia | June 2005 | February 2011 |
| NCT03751488 | Completed | Phase 1 | A Study to Determine Pharmacokinetic Characteristics of LY03010 Versus INVEGA SUSTENNA® in Schizophrenia Patients | December 12, 2018 | July 24, 2019 |
| NCT03935854 | Completed | N/A | Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness | February 13, 2019 | August 11, 2022 |
| NCT00645372 | Completed | Phase 3 | A Study to Compare the Efficacy and Safety of Ziprasidone and Risperidone for the Treatment of Schizophrenia in Chinese Patients | July 2004 | May 2005 |
| NCT00249288 | Completed | Phase 4 | Folate Supplementation in Schizophrenia | December 2003 | June 2008 |
| NCT02390271 | Completed | Phase 4 | How Reducing Anxiety in Schizophrenia | June 2010 | June 2011 |
| NCT00018668 | Completed | Phase 4 | Antipsychotic Response in Schizophrenia | October 2000 | September 2004 |
| NCT02392468 | Completed | Phase 1 | Study of Systemic and Ocular Safety and Pharmacokinetics of BI 409306 in Patients With Schizophrenia, Alzheimer's Disease, and Healthy Volunteers | April 15, 2015 | August 10, 2017 |
| NCT00981526 | Completed | Phase 4 | Telmisartan as an Adjunctive Treatment for Metabolic Problems in Patients With Schizophrenia | March 2009 | May 2012 |
| NCT03648268 | Completed | N/A | Using Transcranial Magnetic Stimulation (TMS) to Understand 'Negative' Symptoms of Schizophrenia | May 2, 2019 | December 22, 2023 |
| NCT00339170 | Completed | N/A | Cognitive Training and Enhanced Supported Employment in Schizophrenia | April 2000 | July 2013 |
| NCT00080327 | Completed | Phase 4 | Study of Three Doses of Aripiprazole in Patients With Acute Schizophrenia | November 2003 | September 2004 |
| NCT00923078 | Completed | N/A | Neurophysiological Targets for Cognitive Training in Schizophrenia | November 2010 | October 2014 |
| NCT02105064 | Completed | N/A | Repetitive Transcranial Magnetic Stimulation (rTMS) as an add-on Treatment for Resistant Obsessive-compulsive Symptoms in Patients With Schizophrenia | July 2011 | February 2016 |
| NCT00567710 | Completed | Phase 2 | A Six-week, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center, Phase II Study | July 2008 | September 2009 |
| NCT03548155 | Completed | N/A | Berberine Effects on Clinical Symptoms and Metabolic Disturbance in Patients With Schizophrenia | July 24, 2014 | May 8, 2017 |
| NCT00470106 | Completed | N/A | Improving Basic and Social Cognition in Veterans With Schizophrenia | September 2007 | September 2009 |
| NCT02411526 | Completed | Phase 1 | Safety and PK Trial With Injectable ZX003 (Risperidone-SABER®) Compared to Risperdal® Consta® in Stable Schizophrenia | February 2015 | September 2015 |
| NCT00796432 | Completed | Phase 1 | A Study of Dopamine Type 2 (D2) Receptor Occupancy Following a Single Oral Dose of OROS Paliperidone | March 2003 | June 2003 |
| NCT00649064 | Completed | Phase 4 | A Study of the Effects of Ziprasidone for the Treatment of Schizophrenia or Schizoaffective Disorder in Patients Who Were Switched From Other Antipsychotic Drugs | December 2003 | September 2004 |
| NCT00216580 | Completed | Phase 3 | A Pilot Study of the Use of Risperidone Long Acting Injectable in the Treatment of Patients With Recent Onset Psychosis | February 2004 | December 2006 |
| NCT01579422 | Completed | Phase 1 | Social Cognitive Training for Psychosis: Treatment Development | May 2012 | December 2015 |
| NCT02167620 | Completed | Phase 4 | Metformin in Co-morbid Diabetes or Prediabetes and Serious Mental Illness | June 2014 | March 2018 |
| NCT04038788 | Completed | N/A | Add-on HD Hf-tRNS Over Bilateral DLPFC for Treating Patients With Schizophrenia | October 24, 2018 | May 17, 2019 |
| NCT03774927 | Completed | N/A | High Frequency rTMS Treatment for Cognitive Impairments in Chronic Schizophrenia Patients | January 1, 2017 | November 30, 2018 |
| NCT00782899 | Completed | Four Dimensions in Schizophrenia | October 2008 | September 2009 | |
| NCT05542264 | Completed | Phase 1 | A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia | November 15, 2022 | February 12, 2024 |
| NCT01181934 | Completed | Early Phase 1 | The Effect of Nicotine on Arousal, Cognition and Social Cognition in Young and Elderly Healthy Subjects. | May 2010 | February 2011 |
| NCT02054702 | Completed | Phase 3 | Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute Schizophrenia | February 2014 | July 2014 |
| NCT02565524 | Completed | N/A | the Phenotypic and Genetic Profile of Patients With Early Onset Schizophrenia Associated With Autism Spectrum Disorder. | May 18, 2014 | May 30, 2023 |
| NCT00345033 | Completed | Phase 4 | Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia | March 2005 | October 2010 |
| NCT02161718 | Completed | Phase 2 | A Study of ALKS 3831 in Subjects With Schizophrenia and Alcohol Use Disorder | May 2014 | February 1, 2017 |
| NCT00176423 | Completed | Phase 4 | Efficacy Study of Galantamine for Cognitive Impairments in Schizophrenia | May 2002 | December 2006 |
| NCT00294008 | Completed | A Study to Evaluate Treatment Adherence in Schizophrenia With Long Acting Risperidone Microspheres (e-STAR) | December 2004 | June 2009 | |
| NCT00161018 | Completed | Phase 3 | New Antipsychotic Strategies: Quetiapine and Risperidone vs. Fluphenazine in Treatment Resistant Schizophrenia | November 2003 | November 2004 |
| NCT01466439 | Completed | Phase 2 | Repetitive Transcranial Magnetic Stimulation (rTMS) and P50 Evoked Potential Component | May 2011 | June 2013 |
| NCT00042159 | Completed | N/A | Transcranial Magnetic Stimulation (TMS) Treatment for Patients With Persistent Auditory Hallucinations | July 2002 | June 2004 |
| NCT03093064 | Completed | Phase 1 | Inflammatory Response In Schizophrenia | April 1, 2017 | August 7, 2023 |
| NCT01786239 | Completed | N/A | Omega-3 Dietary Supplements in Schizophrenia | May 2013 | September 2015 |
| NCT00945503 | Completed | Phase 1 | Positron Emission Tomography (PET) Study to Describe the Relationship Between Plasma Concentrations and Brain Gly-T1 Occupancy of GSK1018921 Over Time. | May 19, 2008 | December 22, 2008 |
| NCT03333603 | Completed | Phase 4 | Pharmacokinetics and Safety Studies of Esomeprazole Use in Schizophrenia Patients | May 23, 2016 | January 23, 2017 |
| NCT00101634 | Completed | Phase 3 | Efficacy and Safety of a Long Acting Anti-Psychotic Versus Placebo in Patients With Schizophrenia | December 2004 | March 2006 |
| NCT01248195 | Completed | Phase 4 | Optimization of Treatment and Management of Schizophrenia in Europe | May 2011 | April 2016 |
| NCT01041092 | Completed | Phase 4 | Double Blind, Placebo-controlled Study of Raloxifene for Negative Symptoms of Schizophrenia in Postmenopausal Women | June 2004 | December 2009 |
| NCT00982020 | Completed | Phase 4 | Study in Adolescents With Schizophrenia or Bipolar Disorder | September 2009 | May 2013 |
| NCT01511510 | Completed | Phase 1 | Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Repeated Doses of PF-04958242 in Healthy Volunteers | June 2011 | November 2011 |
| NCT01663532 | Completed | Phase 3 | Trial of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in the Acute Treatment of Adults With Schizophrenia | October 2012 | September 2013 |
| NCT01378403 | Completed | Evaluation of Dorsal Visual Stream in Patients With Schizophrenia | September 2007 | July 2010 | |
| NCT03273530 | Completed | N/A | Integrated Supported Employment in Mainland China | February 1, 2013 | December 20, 2015 |
| NCT01355952 | Completed | N/A | An Open-Label Pilot Trial of Alpha Lipoic Acid (ALA) for Weight Loss in Schizophrenia | May 2011 | December 2012 |
| NCT00509067 | Completed | Phase 2 | Use of Galantamine and CDP-choline (Citicoline) to Treat Adults With Schizophrenia | November 2007 | March 2011 |
| NCT02720263 | Completed | Phase 1 | A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP4345 in Patients With Schizophrenia | March 28, 2016 | June 8, 2017 |
| NCT00331825 | Completed | Phase 4 | Risperidone and Olanzapine for the Schizophrenic Patients With Neuroleptic-Induced Acute Dystonia or Parkinsonism | July 2000 | July 2003 |
| NCT02717195 | Completed | Phase 3 | Effect of Lu AF35700 in Patients With Treatment-resistant Schizophrenia | April 2016 | October 8, 2018 |
| NCT00150176 | Completed | Phase 3 | To Determine Long Term Efficacy and Safety of Asenapine in Schizophrenic Patient Population (A7501012)(COMPLETED)(P05770) | April 2005 | July 2008 |
| NCT01992913 | Completed | N/A | Building Employment Skills Through Therapy for Veterans | June 12, 2015 | August 31, 2020 |
| NCT01706965 | Completed | Phase 1/Phase 2 | Kuvan in People With Schizophrenia and Schizoaffective Disorder | October 2012 | June 2016 |
| NCT04173572 | Completed | N/A | Targeting Physical Health in Schizophrenia: Physical Activity Can Enhance Life Randomized Control Trial | December 20, 2019 | March 23, 2022 |
| NCT01551979 | Completed | N/A | Therapeutic Efficacy of Transcranial Magnetic Stimulation in Schizophrenia | February 2012 | November 2015 |
| NCT02713282 | Completed | Phase 3 | A Study of Transition to the Paliperidone Palmitate 3-Month Formulation In Participants With Schizophrenia Previously Stabilized on the Paliperidone Palmitate 1-Month Formulation | April 28, 2016 | March 26, 2018 |
| NCT01654601 | Completed | Phase 1 | A Study to Compare the Pharmacokinetics Profile of DWCZP Tablet 100mg and Clozaril® Tablet 100mg | June 2012 | August 2013 |
| NCT01683539 | Completed | N/A | Understanding How Cognitive Remediation Works | September 2012 | March 11, 2019 |
| NCT03005769 | Completed | Demographic and Clinical Predictors of Persistence in Patients Treated With Aripiprazole Once-monthly in Italy | December 2016 | July 2017 | |
| NCT00210691 | Completed | Phase 3 | A Study of Long-acting Injectable Risperidone in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder | December 1999 | February 2004 |
| NCT02110771 | Completed | N/A | Efficacy Study of GAÏA Program Cognitive Remediation of Facial Affects Processing in Schizophrenia | May 2012 | October 2015 |
| NCT00376233 | Completed | Niacin Flushing as Marker of Cannabis Effects on Arachidonic Acid Pathways in Schizophrenia | February 2004 | June 2005 | |
| NCT00085891 | Completed | Phase 3 | Efficacy & Safety of Quetiapine Fumarate (SEROQUEL) & Placebo in the Treatment of Acutely Ill Patients With Schizophrenia | June 2004 | September 2005 |
| NCT01412866 | Completed | N/A | Electronic Decision Support Systems for Smokers With Severe Mental Illness | May 2011 | May 2012 |
| NCT00077727 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Galantamine Hydrobromide on Cognitive Impairment in Patients With Schizophrenia. | March 2003 | February 2005 |
| NCT04294719 | Completed | A Study of Cognitive Adaptation Training in Inpatient Forensic Environments | December 12, 2019 | June 30, 2020 | |
| NCT00723606 | Completed | Phase 3 | A Randomized, Open-Label, Multi-Center Study To Evaluate The Efficacy And Safety Of Intramuscular Ziprasidone In Patients With Agitation | September 2008 | July 2009 |
| NCT00523783 | Completed | Seroquel Long-Term NIS for Schizophrenia Patients | May 2007 | May 2008 | |
| NCT00304473 | Completed | Phase 3 | Fast Titration in the Treatment of Schizophrenia, Taiwan | August 2004 | April 2006 |
| NCT03959735 | Completed | N/A | High Intensity Interval Training in Severe Mental Illness | October 10, 2019 | August 30, 2021 |
| NCT00791193 | Completed | Phase 1 | A Pharmacokinetic Study of the Relative Bioavailability of Paliperidone ER Formulations With Different Release Profiles and a Comparison to Paliperidone IR | March 2007 | May 2007 |
| NCT00239109 | Completed | Phase 4 | Ziprasidone Versus Olanzapine In The Treatment Of Schizophrenia. | April 2003 | February 2007 |
| NCT00431574 | Completed | N/A | Antipsychotic Medication Extended Dosing Study | August 2002 | October 2007 |
| NCT01362426 | Completed | Paliperidone Palmitate Effectiveness Assessment Registry - Longitudinal (PEARL) | March 2011 | May 2013 | |
| NCT00206986 | Completed | N/A | Will Decreased Noradrenergic Activity Normalize Information Processing in Patients With Schizophrenia? | May 2005 | December 2011 |
| NCT01289080 | Completed | Phase 1 | Trial Evaluating OPC-34712 in Subjects With Normal Renal Function and Renally Impaired Subjects | January 2011 | January 2012 |
| NCT02887794 | Completed | N/A | Basic Auditory Processing and Auditory Hallucinations | October 6, 2016 | July 31, 2021 |
| NCT00374244 | Completed | Phase 2 | Efficacy of Pimozide Augmentation for Clozapine Partial Response | January 2004 | June 2011 |
| NCT02901587 | Completed | Phase 1 | Study Investigating the Effect of Lu AF35700 on Cardiac Repolarization in Men and Women With Schizophrenia and Schizoaffective Disorder | September 2016 | April 18, 2018 |
| NCT01880255 | Completed | N/A | rTMS for Working Memory Deficits in Schizophrenia | June 2013 | January 7, 2019 |
| NCT02079844 | Completed | Phase 1 | Roflumilast Plus Antipsychotics Proof of Mechanism Study in Schizophrenia | March 2014 | June 2015 |
| NCT01716858 | Completed | Phase 2 | An Open Study of Sulforaphane-rich Broccoli Sprout Extract in Patients With Schizophrenia | October 2012 | March 2014 |
| NCT01259427 | Completed | Phase 2 | Reducing Internalized Stigma in People With Serious Mental Illness | October 2011 | September 2015 |
| NCT02188732 | Completed | N/A | Self-Management Training and Automated Telehealth to Improve SMI Health Outcomes | January 2015 | July 31, 2021 |
| NCT03820362 | Completed | The Role of Personal Identity in Psychotic Symptoms: a Study With the Repertory Grid Technique | February 2016 | November 2018 | |
| NCT00044655 | Completed | Phase 4 | Switching Medication to Treat Schizophrenia | July 2001 | March 2009 |
| NCT00403546 | Completed | Phase 3 | High-Dose Oral Ziprasidone Versus Conventional Dosing in Participants With Residual Schizophrenia Symptoms | January 2006 | May 2011 |
| NCT00159081 | Completed | Phase 4 | One Year Drug Treatment in First-Episode Schizophrenia | November 2000 | June 2005 |
| NCT03208036 | Completed | N/A | Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness | July 15, 2018 | February 28, 2022 |
| NCT02421237 | Completed | N/A | Trial of Treatment for Internalized Stigma in Schizophrenia | March 2013 | July 31, 2018 |
| NCT00145444 | Completed | Phase 3 | Kahn Study; Investigation Of The Efficacy Of Ziprasidone Versus Olanzapine In The Management Of Recent-Onset Psychosis; A Flexible-Dose, Parallel Group, Double-Blind Study | March 2003 | November 2005 |
| NCT00615511 | Completed | Phase 2 | Efficacy of Pregnenolone in Patients With Schizophrenia | June 2007 | December 2014 |
| NCT01519557 | Completed | Early Phase 1 | Pharmacologic and Clinical Testing of a D1 Agonist for Cognitive Enhancement in Neuropsychiatric Disorders | April 2011 | November 2013 |
| NCT00749970 | Completed | Validity of the Spanish Version of Subjective Well-being Under Neuroleptics Scale (SWN-K) in Patients With Schizophrenia | July 2008 | January 2009 | |
| NCT01828931 | Completed | N/A | Lifestyle Intervention for Diabetes and Weight Management in Psychosis | December 2012 | November 2015 |
| NCT02567032 | Completed | Early Phase 1 | Adult Study Oxytocin - Behavioral | October 2010 | August 2019 |
| NCT00249119 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Risperidone Compared With Haloperidol in Patients With Chronic Schizophrenia | December 1991 | |
| NCT00156715 | Completed | Phase 4 | Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder | March 2004 | October 2008 |
| NCT00194025 | Completed | Phase 4 | Valproate in Late Life Schizophrenia | November 2004 | November 2006 |
| NCT01855074 | Completed | Phase 4 | An Efficacy and Safety Study of Risperidone Long-Acting Microspheres in Participants With Schizophrenia, Schizophreniform or Schizoaffective Disorders | November 2007 | February 2009 |
| NCT00663039 | Completed | Phase 2 | Effects of Oxytocin Nasal Spray on Social Affiliation | October 2009 | July 2015 |
| NCT04221269 | Completed | N/A | Suicide Prevention Intervention for Schizophrenia-Spectrum Disorders | December 1, 2020 | June 1, 2023 |
| NCT00645944 | Completed | N/A | Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia | April 2008 | April 2011 |
| NCT01585493 | Completed | Phase 3 | CHANGE -it is About Life | December 2012 | June 2016 |
| NCT02970929 | Completed | Phase 2 | An Extension Study of Safety and Tolerability of SEP-363856 in Adult Subjects With Schizophrenia | January 31, 2017 | January 29, 2019 |
| NCT06315049 | Completed | N/A | Music Therapy to Reduce Anxiety in Community-Dwelling Individuals With Severe Mental Illness | June 26, 2023 | July 31, 2023 |
| NCT00320489 | Completed | Phase 3 | Olanzapine Pamoate Depot Versus Oral Olanzapine on Treatment Outcomes in Outpatients With Schizophrenia | April 2006 | September 2009 |
| NCT04870710 | Completed | N/A | Feasibility Electrical Stimulation Study for Visual Hallucinations | October 1, 2020 | January 2, 2022 |
| NCT00308360 | Completed | Phase 4 | Risperidone Alone Vs. Risperidone Plus Valproate in the Treatment of Patients With Schizophrenia and Hostility | September 1999 | April 2004 |
| NCT04545294 | Completed | N/A | Theta tACS During Working Memory Training: A Pilot Study of the Effects on Negative Symptoms of Schizophrenia | August 14, 2019 | April 10, 2020 |
| NCT02212041 | Completed | N/A | Electronic Cigarettes in Smokers With Mental Illness | September 24, 2014 | May 2, 2017 |
| NCT02621983 | Completed | N/A | Aerobic Exercise for Cognition in Schizophrenia | January 1, 2016 | July 1, 2018 |
| NCT02067975 | Completed | Phase 2/Phase 3 | Tryptophan MRI in People With Schizophrenia and Healthy Controls | September 2014 | December 2019 |
| NCT00401089 | Completed | Phase 1/Phase 2 | Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia | December 2002 | October 2007 |
| NCT00193687 | Completed | Phase 3 | Bifeprunox in the Treatment of Schizophrenia | September 2005 | January 2008 |
| NCT00197093 | Completed | Phase 1 | In-Patient Study In Schizophrenic Patients | September 2004 | |
| NCT00222807 | Completed | Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes Mellitus | August 2003 | March 2016 | |
| NCT00970281 | Completed | Phase 3 | A Study of Olanzapine in Patients With Schizophrenia | September 2009 | April 2011 |
| NCT04187560 | Completed | Phase 1 | Safety and Tolerability of Single and Multiple Doses of LB-102 in Healthy Adults | January 22, 2020 | November 9, 2020 |
| NCT03514212 | Completed | N/A | Promoting Physical Activity in People With Schizophrenia. | November 24, 2015 | August 31, 2016 |
| NCT00709202 | Completed | Phase 2 | Efficacy and Tolerability Study of Betahistine to Ameliorate Antipsychotic Associated Weight Gain | July 2008 | December 2016 |
| NCT01299389 | Completed | Phase 3 | An Efficacy and Safety Study of Paliperidone Palmitate in Participants With Schizophrenia | October 2010 | May 2012 |
| NCT03873337 | Completed | N/A | Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI) | April 22, 2019 | January 31, 2022 |
| NCT00492349 | Completed | Phase 4 | Varenicline Adjunctive Treatment in Schizophrenia | May 2007 | April 2011 |
| NCT01493726 | Completed | Phase 1 | A Study of ALKS 9072 in Subjects With Chronic Stable Schizophrenia | December 2011 | June 2013 |
| NCT00155818 | Completed | Mutation Screening and Translocation Detection of DISC1 Gene in Schizophrenia | August 2003 | July 2004 | |
| NCT05662137 | Completed | N/A | The Effect of Recognition and Expression of Emotions Program Applied to Schizophrenia Patients | January 15, 2023 | May 15, 2023 |
| NCT01090440 | Completed | Phase 1 | Pharmacokinetics, Effect of Food, Safety and Tolerability of a New Tablet Formulation of GSK1144814 in Healthy Subjects | September 1, 2009 | October 9, 2009 |
| NCT03338179 | Completed | N/A | Evaluation of Metamemory in Patients With Schizophrenia | February 8, 2011 | May 23, 2016 |
| NCT00206570 | Completed | Phase 2 | Clinical Estradiol Trial in Women With Schizophrenia | January 2001 | December 2004 |
| NCT00329810 | Completed | Phase 4 | Effect on Cognitive Function of a Treatment With Aripiprazole | March 2005 | March 2006 |
| NCT03076346 | Completed | Neural Biomarkers of Clozapine Response | September 1, 2017 | December 31, 2020 | |
| NCT01399450 | Completed | Phase 4 | Paliperidone ER(Invega®) on Depressive Symptoms of Schizophrenia Patients | August 2011 | November 2016 |
| NCT01448720 | Completed | Phase 3 | Treatment of Patients With Recently Exacerbated Schizophrenia With Paliperidone Palmitate | September 2011 | December 2013 |
| NCT00406718 | Completed | N/A | Improving Adherence to Oral Antipsychotic Medications in People With Schizophrenia | November 2006 | July 2013 |
| NCT01610011 | Completed | N/A | Acute Glycine Pharmacodynamic Study | July 2010 | December 2013 |
| NCT00322023 | Completed | Phase 2 | Safety and Effectiveness of D-serine in Schizophrenia | March 2006 | January 2009 |
| NCT03187769 | Completed | Phase 3 | Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder | June 8, 2017 | January 3, 2022 |
| NCT01116830 | Completed | Phase 1 | A Study of the Effect of RO4917838 on Biomarker Measures of Cognitive Dysfunction in Participants With Schizophrenia and Schizoaffective Disorder | November 2010 | February 2014 |
| NCT00272597 | Completed | Phase 4 | Risperidone LA Heathcare Resource Study | September 2005 | October 2010 |
| NCT04849026 | Completed | Phase 1 | Bioequivalence Study in Patients With Schizophrenia by Using Clozaril 100 mg Tablet (Clozapine) and WID-CLZ18 | January 15, 2021 | August 14, 2022 |
| NCT00351000 | Completed | Phase 4 | Ziprasidone for Clozapine- or Olanzapine-Associated Diabetes Mellitus | January 2005 | March 2007 |
| NCT01625000 | Completed | Phase 2/Phase 3 | Safety and Efficacy of MP-214 in Patients With Schizophrenia | May 2012 | October 2015 |
| NCT00108199 | Completed | N/A | Generalization of Training in Schizophrenia | October 2001 | September 2004 |
| NCT00103571 | Completed | Phase 4 | Olanzapine Versus Aripiprazole in the Treatment of Acutely Ill Patients With Schizophrenia | July 2004 | August 2006 |
| NCT01481883 | Completed | Phase 4 | Selective Estrogen Receptor Modulators (SERMs) - A Potential Treatment for Psychotic Symptoms of Schizophrenia in Men? | January 2012 | February 2019 |
| NCT05712928 | Completed | N/A | eMove - Dance/Movement Therapy Study | June 29, 2021 | December 31, 2022 |
| NCT00215579 | Completed | Phase 4 | Determining the Effects of Risperdal Consta in Patients With Psychotic Disorders and Incomplete Adherence | April 2004 | April 2006 |
| NCT01570972 | Completed | N/A | Mediators and Moderators of Treatment Outcome in Recent-Onset Psychosis | February 2010 | April 2017 |
| NCT00742079 | Completed | Phase 4 | Using D-cycloserine to Enhance the Benefits of Cognitive Behavioral Therapy for Schizophrenia | September 2006 | December 2010 |
| NCT03466112 | Completed | N/A | Aerobic Exercise for the Improvement of Cognition and Enhancement of Recovery in Post-acute Schizophrenia | June 2016 | December 2021 |
| NCT00585390 | Completed | Phase 2/Phase 3 | Omega-3 Fatty Acid Deficiency Replacement in Early Schizophrenia | January 2008 | November 2009 |
| NCT04922593 | Completed | Phase 1 | Relative Bioavailability of LY03010 Compared to Listed Drug | January 13, 2021 | April 15, 2022 |
| NCT01998516 | Completed | Emotional Intelligence in Schizophrenia and Bipolar-I- Disorder | December 2013 | July 31, 2017 | |
| NCT02320032 | Completed | Phase 1 | An Open-Label Study of Aripiprazole Lauroxil in Subjects With Stable Schizophrenia | December 2014 | April 2016 |
| NCT03198364 | Completed | N/A | Development of a Mobile Heath Augmented Brief Suicide Prevention Intervention for People With SMI | March 1, 2018 | June 30, 2021 |
| NCT00048828 | Completed | Phase 4 | Treating Drug-Resistant Childhood Schizophrenia | October 2001 | June 2006 |
| NCT05258123 | Completed | N/A | Ginkgo Biloba Extract in the Treatment of Schizophrenia | May 15, 2017 | August 15, 2018 |
| NCT00245206 | Completed | Phase 4 | Side Effects of Newer Antipsychotics in Older Adults | August 2005 | October 2010 |
| NCT00320723 | Completed | Phase 4 | Nicotine Replacement Therapy for Smoking Cessation in Schizophrenia | July 2001 | December 2005 |
| NCT00287820 | Completed | Phase 4 | Comparative Effects of Chronic Treatment With Olanzapine and Risperidone on Glucose and Lipid Metabolism | February 2004 | September 2007 |
| NCT01852331 | Completed | Phase 2 | Peony-Glycyrrhiza Decoction (PGD) for Antipsychotic-induced Hyperprolactinemia in Patients With Schizophrenia | January 2013 | November 2014 |
| NCT00797277 | Completed | Phase 3 | Intramuscular (IM) Olanzapine Versus IM Haloperidol Plus Lorazepam for Acute Agitation in Schizophrenia | July 2006 | June 2009 |
| NCT00148447 | Completed | Phase 3 | The Efficacy of Escitalopram for Negative Symptoms in Schizophrenia | November 2004 | September 2005 |
| NCT02404155 | Completed | N/A | Biomarker and Safety Study of Clozapine in Patients With Benign Ethnic Neutropenia (BEN) | July 2015 | October 26, 2021 |
| NCT01160991 | Completed | N/A | Effect of Atypical Antipsychotic Drugs Olanzapine and Amisulpride on Glucose Metabolism | May 2004 | October 2006 |
| NCT02174523 | Completed | Phase 1 | Pharmacokinetic Study of Lurasidone After Multiple Oral Administration in Healthy Human Subjects | April 2014 | April 2014 |
| NCT02035202 | Completed | N/A | Real-Time Mobile Cognitive Behavioral Intervention for Serious Mental Illness | October 2013 | May 2017 |
| NCT00034801 | Completed | Phase 4 | Olanzapine Versus Active Comparator in the Treatment of Depression in Patients With Schizophrenia | September 2001 | March 2003 |
| NCT00816907 | Completed | Phase 4 | The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study) | January 2009 | March 2010 |
| NCT01346163 | Completed | Phase 1 | Add On Treatment for Cognitive Deficits in Schizophrenia | April 2009 | November 2010 |
| NCT00320671 | Completed | Phase 4 | Comparison of Aripiprazole and Risperidone for the Treatment of People With First-Episode Psychosis | December 2005 | December 2015 |
| NCT02686697 | Completed | Phase 2/Phase 3 | Carnosine and Cognitive Training in Schizophrenia | December 1, 2015 | July 19, 2022 |
| NCT02669758 | Completed | Phase 3 | A Long-Term Safety and Tolerability Study of ALKS 3831 in Adults With Schizophrenia | January 20, 2016 | June 29, 2018 |
| NCT01072617 | Completed | N/A | Cerebellar rTMS for the Treatment of Schizophrenic Patients | February 2008 | April 2009 |
| NCT01981759 | Completed | Phase 4 | D-Cycloserine Augmentation of Cognitive Behavioral Therapy for Delusions | February 2014 | October 2017 |
| NCT01822418 | Completed | Phase 4 | Agomelatine Treatment of Depression in Schizophrenia (AGOPSYCH) | January 2013 | December 2015 |
| NCT01181960 | Completed | Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health Organizations | August 2010 | November 2013 | |
| NCT00261430 | Completed | Phase 4 | A 2-year Study of Patients With Schizophrenia Who Are Treated With Long-acting Injectable Risperidone. | October 2004 | |
| NCT01235585 | Completed | Phase 3 | A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25306) | December 2010 | September 2014 |
| NCT00074477 | Completed | Phase 2 | Safety and Efficacy of an Anti-Psychotic in Patients With Schizophrenia | October 2003 | July 2004 |
| NCT01309373 | Completed | An Epidemiological Study to Assess the Psychosocial and Symptomatic Remission and Community Integration Status in Patients With Schizophrenia | November 2010 | August 2011 | |
| NCT00712686 | Completed | Phase 3 | Comparative Study of Aripiprazole and Olanzapine in the Treatment of Patients With Acute Schizophrenia | June 2000 | December 2003 |
| NCT02006628 | Completed | Phase 2 | A Study of GWP42003 as Adjunctive Therapy in the First Line Treatment of Schizophrenia or Related Psychotic Disorder | February 25, 2014 | January 8, 2015 |
| NCT00111189 | Completed | Phase 3 | A Study of the Efficacy (Effectiveness) of Paliperidone Palmitate in the Prevention of Recurrence of the Symptoms of Schizophrenia. | February 2005 | February 2008 |
| NCT04309370 | Completed | N/A | Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia | March 12, 2020 | April 15, 2022 |
| NCT01279213 | Completed | Phase 4 | Clozapine/Paliperidone Versus Clozapine/Placebo in Resistant Schizophrenia | January 2009 | December 2009 |
| NCT01701609 | Completed | N/A | Cognitive Remediation Therapy (CRT) in Adolescents With EOS | January 2007 | July 2013 |
| NCT02118610 | Completed | N/A | Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity | September 2014 | June 2019 |
| NCT00659919 | Completed | Phase 4 | Treatment of Neuroleptic Induced Acute Akathisia With Trazodone | November 2000 | December 2003 |
| NCT03801551 | Completed | N/A | Validation of a Tool for the Dimensional Assessment of Apathy in a Population Suffering From Schizophrenia. | July 3, 2018 | October 22, 2020 |
| NCT00169689 | Completed | N/A | Repetitive Transcranial Magnetic Stimulation | June 2003 | August 2007 |
| NCT00554840 | Completed | Phase 2 | Comparison of Varenicline and Placebo for Smoking Cessation in Schizophrenia | November 2007 | April 2011 |
| NCT03617783 | Completed | Phase 4 | Prebiotic Treatment in People With Schizophrenia - Pilot Study | July 18, 2019 | April 5, 2022 |
| NCT01323205 | Completed | Phase 2 | Investigation of the Safety, Tolerability and Potential Therapeutic Effects of JNJ-40411813 in Patients With Schizophrenia | May 2011 | December 2012 |
| NCT01526395 | Completed | N/A | Decreasing the Use of Unmodified Electroconvulsive Therapy (ECT) in an Indian Hospital | August 2011 | April 2012 |
| NCT00824031 | Completed | Study of Mental Care in Spain | January 2009 | July 2009 | |
| NCT01012167 | Completed | Phase 2 | Oxytocin or Galantamine Versus Placebo for the Treatment of Negative Symptoms and Cognitive Impairments in Schizophrenia | February 2010 | July 2014 |
| NCT03859973 | Completed | Phase 2 | This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia | April 15, 2019 | November 4, 2022 |
| NCT00666432 | Completed | Bipolar and Schizophrenia Consortium for Parsing Intermediate Phenotypes | May 2008 | November 22, 2019 | |
| NCT00380224 | Completed | Phase 3 | Study Comparing the Affect of Bifeprunox Vs Olanzapine on Weight During the Treatment of Outpatients With Schizophrenia. | July 2006 | September 2007 |
| NCT00235274 | Completed | Phase 2 | Effects of RG1068 (Secretin) on Information Processing in Schizophrenia | November 2005 | August 2006 |
| NCT00261794 | Completed | N/A | Cognitive Remediation for Schizophrenia | November 2004 | September 2007 |
| NCT00143351 | Completed | Phase 3 | Mozart Relapse Study | June 2003 | September 2005 |
| NCT00202007 | Completed | Phase 2 | Efficacy and Safety Study of Aripiprazole to Treat Schizophrenia | February 2005 | July 2005 |
| NCT02458924 | Completed | Phase 2/Phase 3 | Niacin Skin Flush Response in Patients With Schizophrenia | January 2014 | September 2014 |
| NCT01157351 | Completed | Phase 4 | 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated | May 2010 | December 2013 |
| NCT00711464 | Completed | Phase 4 | Modafinil Effects on Cognition in Schizophrenia Patients | May 2008 | July 2012 |
| NCT01431092 | Completed | Phase 4 | Melatonin Versus Placebo for Benzodiazepine Discontinuation in Patients With Schizophrenia | October 2011 | June 2014 |
| NCT02142556 | Completed | Phase 3 | The Efficacy and Safety of Quetiapine XR in Patients With Schizophrenia Switched From Other Antipsychotics | November 2008 | March 2012 |
| NCT00982982 | Completed | Early Phase 1 | Effects of Delta-9-THC and Iomazenil in Healthy Humans | February 11, 2009 | February 22, 2013 |
| NCT00149734 | Completed | Phase 3 | Addition of Ondansetron to Ongoing Antipsychotic Treatment for Schizophrenia | January 2005 | May 2010 |
| NCT00331981 | Completed | Phase 4 | Amisulpride in Schizophrenic Patients | February 2004 | |
| NCT01052103 | Completed | Phase 2 | A Study of LY2140023 in Schizophrenia Patients With Prominent Negative Symptoms | January 2010 | June 2012 |
| NCT00254787 | Completed | Phase 2 | Rapid Dose Escalation of Quetiapine Versus Conventional Escalation in Acute Schizophrenic Patients | June 2005 | January 2006 |
| NCT02478827 | Completed | N/A | A Trial of Cognitive Training in Schizophrenia | March 1, 2016 | August 31, 2017 |
| NCT01104779 | Completed | Phase 3 | Safety and Efficacy of Cariprazine in Schizophrenia | April 27, 2010 | December 15, 2011 |
| NCT00672373 | Completed | Phase 3 | Extract of Ginkgo Biloba and Tardive Dyskinesia | December 2006 | August 2007 |
| NCT00688259 | Completed | N/A | Cognitive-Behavioral Therapy in Veterans With Schizophrenia | April 2009 | January 2015 |
| NCT00873249 | Completed | Effect of Daily Short Message System (SMS) Reminders on Medication Adherence to Oral Antipsychotics in Patients With Schizophrenia | April 2009 | March 2010 | |
| NCT01321177 | Completed | N/A | An Integrated Program for the Treatment of First Episode of Psychosis | July 2010 | July 2017 |
| NCT00528905 | Completed | Phase 2 | Proof of Concept Study of Cognitive Improvement in Patients With Schizophrenia | August 2007 | November 2008 |
| NCT03064776 | Completed | N/A | Study of m-RESIST, an m-Health Program for Treatment-resistant Schizophrenia | March 1, 2017 | June 1, 2019 |
| NCT02086162 | Completed | N/A | Randomized Controlled Trial (RCT) of a Motivational Decision Support System | April 2014 | July 2016 |
| NCT00758030 | Completed | Phase 1 | Study Evaluating and Comparing Single Dose and Multiple Dose Pharmacokinetics of ER OROS Paliperidone in Healthy Japanese and Caucasian Adults. | March 2004 | July 2004 |
| NCT00167310 | Completed | Phase 2 | Decreasing Risk of Coronary Artery Disease in Schizophrenia by Omega-3 Fatty Acid Supplementation | September 2005 | December 2015 |
| NCT00810667 | Completed | Phase 2 | Efficacy Study Exploring the Effect of Lu AE58054 as Augmentation Therapy in Patients With Schizophrenia | November 2008 | February 2010 |
| NCT01810783 | Completed | Phase 3 | Brexpiprazole in Patients With Schizophrenia | July 2013 | December 2015 |
| NCT00150215 | Completed | Phase 1 | A First In Human Study Of PF-00184562 In Healthy Volunteers | July 2005 | October 2005 |
| NCT02600741 | Completed | Family Intervention in Recent Onset Schizophrenia Treatment (FIRST) | July 24, 2015 | July 5, 2018 | |
| NCT00668837 | Completed | Phase 3 | A 52 Week Open-label Extension Trial Following the Double-blind Efficacy and Safety Study R076477-SCH-305. | February 2004 | June 2006 |
| NCT01354353 | Completed | Phase 1 | A Study of Safety and Tolerability in Subjects With Schizophrenia | May 2011 | March 2012 |
| NCT00088049 | Completed | Phase 4 | Study of Olanzapine vs. Aripiprazole in the Treatment of Schizophrenia | October 2003 | July 2007 |
| NCT02547259 | Completed | N/A | Influence of Emotion in a Test Run Forgetfulness | September 2011 | December 2011 |
| NCT01801787 | Completed | N/A | Non-invasive Brain Stimulation for Auditory Verbal Hallucinations in Schizophrenia | March 2013 | December 2015 |
| NCT00515723 | Completed | N/A | Glucose and Lipid Metabolism on Antipsychotic Medication | September 2001 | December 2008 |
| NCT04822883 | Completed | Phase 2 | Safety, Biomarker Study of RL-007 in Subjects With Schizophrenia | April 26, 2021 | October 28, 2021 |
| NCT01196286 | Completed | N/A | Multifamily Psychoeducation and Cognitive Remediation for Recent-Onset Psychosis | June 2010 | April 2017 |
| NCT02868879 | Completed | Anatomical and Structural Connectivity in Two Psychotic Phenotypes : Periodic Catatonia and Cataphasia | September 25, 2006 | September 2019 | |
| NCT00078741 | Completed | Phase 2 | Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder in Individuals With Severe Mental Illness | January 2004 | September 2007 |
| NCT00436371 | Completed | Phase 4 | Amisulpride in Schizophrenic Acute Phase Patients | May 2005 | |
| NCT02642029 | Completed | N/A | Targeting Cerebellum to Treat Psychosis: a Transcranial Magnetic Stimulation (TMS) Study | February 18, 2016 | June 14, 2019 |
| NCT01548612 | Completed | Phase 2 | Add-on Sodium Nitroprusside to Treatment as Usual in Schizophrenia | February 2006 | December 2010 |
| NCT04461119 | Completed | Phase 2 | Study to Determine the Safety, Tolerability, and Efficacy of Evenamide in Patients With Chronic Schizophrenia | June 16, 2020 | March 13, 2021 |
| NCT00711269 | Completed | Phase 3 | Study of SM-13496 (Lurasidone HCl) in Patients With Schizophrenia | June 27, 2008 | April 27, 2010 |
| NCT01081418 | Completed | Phase 4 | Assertive Community Treatment (ACT) in Schizophrenia Spectrum Disorders | April 2005 | April 2009 |
| NCT02566057 | Completed | N/A | Prospective Pharmacogenetic Testing and Clinical Outcomes in Patients With Early-Phase Psychosis | July 10, 2014 | December 31, 2017 |
| NCT04618250 | Completed | N/A | Improving Physical Health in Patients With Psychiatric Disorders in General Practice (SOFIA) | November 6, 2020 | September 30, 2021 |
| NCT03921450 | Completed | N/A | Overcoming Psychomotor Slowing in Psychosis (OCoPS-P) | March 25, 2019 | February 10, 2023 |
| NCT01609153 | Completed | Phase 4 | Comparison of Antipsychotic Combination Treatment of Olanzapine and Amisulpride to Monotherapy | June 2012 | April 2019 |
| NCT00567281 | Completed | N/A | Bilateral Repetitive Transcranial Magnetic Stimulation for Auditory Hallucinations Original Study | October 2007 | September 2012 |
| NCT04030143 | Completed | Phase 1/Phase 2 | A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder | August 1, 2019 | July 8, 2020 |
| NCT01191827 | Completed | fMRI Cholinergic Mechanisms in Schizophrenia | October 2008 | December 2011 | |
| NCT01234779 | Completed | Phase 2 | A Study of RO4917838 (Bitopertin) in Patients With Acute Exacerbation of Schizophrenia | February 2011 | September 2012 |
| NCT02305823 | Completed | Phase 4 | Comparative Study of Aripiprazole, Quetiapine and Ziprasidone in the Treatment of First Episode Nonaffective Psychosis | October 2005 | May 2014 |
| NCT01550666 | Completed | N/A | Treatment Development Targeting Severe and Persistent Negative Symptoms | January 2011 | January 2015 |
| NCT01598220 | Completed | N/A | Computer Assisted Cognitive Remediation Program in Schizophrenia | September 2002 | December 2005 |
| NCT02636842 | Completed | Phase 1 | A Study of Aripiprazole Lauroxil in Subjects With Schizophrenia or Schizoaffective Disorder | December 2015 | June 2016 |
| NCT01870999 | Completed | Phase 1 | A Multiple Dose Safety, Tolerability and Pharmacokinetics Study in Adult Patients With Schizophrenia Following Administration of Aripiprazole IM Depot | November 2007 | October 2008 |
| NCT02451670 | Completed | N/A | Reducing Cardiovascular Risk in Adults With Serious Mental Illness | January 20, 2016 | September 19, 2018 |
| NCT02670291 | Completed | N/A | Treatment of Auditory Hallucinations in Schizophrenia With Bilateral Theta Burst Stimulation | January 2017 | March 2024 |
| NCT03285503 | Completed | Phase 1 | PK Study of Aripiprazole IM Depot for Chinese Patients With Schizophrenia | August 17, 2018 | October 14, 2019 |
| NCT00573300 | Completed | Disturbances of Kynurenine Pathway of Trytophan Metabolism in Schizophrenia: A Quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) Study | January 2006 | May 2009 | |
| NCT00757705 | Completed | Phase 4 | An Efficacy, Safety And Tolerability Study of Flexibly Dosed Paliperidone Extended-Release (ER) in Participants With Schizophrenia | March 2008 | May 2009 |
| NCT01774435 | Completed | Phase 1 | Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)-Risperidone When Risperidone is Administered From a Polyurethane Implant | October 2012 | October 2013 |
| NCT00114595 | Completed | Phase 4 | Ethyl-Eicosapentaenoic Acid and Tardive Dyskinesia | April 2003 | March 2005 |
| NCT00269464 | Completed | Chronic Schizophrenia With Obsessive-Compulsive Symptoms: Comorbidity or a Subtype? | March 2007 | ||
| NCT05352568 | Completed | N/A | Is Cognitive Training an Option? | May 2, 2022 | June 30, 2023 |
| NCT00206960 | Completed | N/A | Dopaminergic, Functional, Structural, and Cognitive Disturbances in First-episode Schizophrenia | January 1998 | September 2010 |
| NCT03388554 | Completed | N/A | The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia | July 2016 | March 2, 2018 |
| NCT03627195 | Completed | Phase 1 | A Study to Determine the Maximum Tolerated Dose of an Investigational Drug in Subjects With Schizophrenia | June 7, 2018 | March 29, 2019 |
| NCT00554658 | Completed | Phase 4 | Quetiapine Induced Neuroplasticity in First-episode Schizophrenic Patients | March 2008 | March 2011 |
| NCT04055181 | Completed | N/A | Influence of rTMS on Symptoms and Cognitive Function in Patients With Psychiatric Disorders | December 1, 2018 | January 30, 2020 |
| NCT00968851 | Completed | Phase 2 | Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia | December 2009 | March 2011 |
| NCT02186769 | Completed | Phase 1 | An Randomized Open-Label PK Study of LY03004 Compared to Risperdal® Consta® in Stable Patients With Schizophrenia or Schizoaffective Disorder | July 2014 | April 2015 |
| NCT02421965 | Completed | N/A | Comparing Mobile Health (mHealth) and Clinic-Based Self-Management Interventions for Serious Mental Illness | June 2015 | December 2017 |
| NCT03818516 | Completed | N/A | Impact of Inflammation on Reward Circuits, Motivational Deficits and Negative Symptoms in Schizophrenia | August 31, 2020 | March 1, 2022 |
| NCT00455715 | Completed | Phase 4 | A Placebo-Controlled Single-Dose Trial of Sildenafil in Schizophrenia | February 2006 | September 2008 |
| NCT00793780 | Completed | N/A | Pilot Trial of Naltrexone for Obesity in Women With Schizophrenia | December 2008 | November 2010 |
| NCT02205099 | Completed | Phase 1/Phase 2 | A Safety, Tolerability, PK and PD Study of Multiple Oral Doses of SKL15508 in Subjects With Stable Schizophrenia | July 2014 | June 2015 |
| NCT00817336 | Completed | Phase 2 | Biomarkers in Schizophrenia | June 2009 | July 2011 |
| NCT02573168 | Completed | N/A | Pharmacogenomic Decision Support With GeneSight Psychotropic to Guide the Treatment With Antipsychotics | January 2016 | September 2020 |
| NCT00061789 | Completed | Phase 2 | Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia | February 2003 | August 2004 |
| NCT05517460 | Completed | N/A | The Efficacy of Auricular Acupressure on Improving Constipation Among Residents in Community Rehabilitation Center | September 6, 2022 | March 15, 2023 |
| NCT00036127 | Completed | Phase 2/Phase 3 | Study of Alternate Formulation of Aripiprazole in Agitated Patients With Schizophrenic Disorders | April 2002 | January 2003 |
| NCT01555814 | Completed | N/A | Optimization of Treatment and Management of Schizophrenia in Europe (OPTIMISE): Substudy Site Copenhagen | May 2011 | October 2016 |
| NCT02874482 | Completed | Cognitive and Emotional Factors in Visual Exploration Among Patients With Schizophrenia | July 2014 | November 17, 2019 | |
| NCT03893825 | Completed | Phase 3 | A Study to Test if TV-46000 is Safe for Maintenance Treatment of Schizophrenia | April 17, 2019 | December 2, 2021 |
| NCT01295372 | Completed | Phase 3 | Safety and Efficacy of Zicronapine in Patients With Schizophrenia | April 2011 | |
| NCT01964404 | Completed | Phase 1 | Cannabis, Schizophrenia and Reward: Self-Medication and Agonist Treatment? | July 2014 | September 18, 2021 |
| NCT00758251 | Completed | Observation of Change in Clinical Global Impression Scores in Schizophrenia Patients Receiving Seroquel XR Treatment | September 2008 | March 2009 | |
| NCT04503954 | Completed | N/A | Efficacy of Chronic Disease Self-management Program in People With Schizophrenia | September 7, 2020 | December 25, 2020 |
| NCT00000387 | Completed | Phase 3 | Self-Management Therapy for Youth With Schizophrenia | April 1998 | January 2005 |
| NCT01788774 | Completed | Phase 1 | Pharmacokinetic, Safety, and Tolerability Study of Risperidone ISM® at Different Dose Strengths | April 2013 | February 2014 |
| NCT02282761 | Completed | Phase 3 | A Trial to Assess the Antipsychotic Efficacy of ITI-007 | November 2014 | September 2015 |
| NCT00268749 | Completed | Phase 2 | Glycine Treatment of Prodromal Symptoms | July 2002 | November 2004 |
| NCT03190161 | Completed | N/A | Music to Reduce Use of Smoking in Patients With Schizophrenia | March 9, 2017 | September 17, 2018 |
| NCT00307203 | Completed | Phase 4 | Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke | August 1998 | February 2004 |
| NCT00392236 | Completed | N/A | Improving Medication Adherence Among People With Schizophrenia Through the Use of 2-way Pagers | April 2006 | December 2009 |
| NCT00445926 | Completed | Phase 1 | Evaluation of the H1-coil Deep TMS in the Treatment of Negative Symptoms and Cognitive Deficit in Schizophrenia | July 2006 | May 2009 |
| NCT00080548 | Completed | Timing of Voluntary Movement in Patients With Schizophrenia | April 6, 2004 | January 6, 2009 | |
| NCT00312949 | Completed | N/A | Effectiveness of an Interactive Educational Website for Improving the Quality of Mental Health Care for People With Schizophrenia | April 2006 | December 2007 |
| NCT00453804 | Completed | Phase 4 | Injectable Versus Oral Naltrexone Treatment of Alcohol Dependence In Serious Mental Illness (SMI) | July 2006 | June 2007 |
| NCT03048370 | Completed | N/A | Reactivity of the Vestibular System to Caloric Vestibular Stimulation in Schizophrenia | January 1, 2019 | December 31, 2023 |
| NCT02022462 | Completed | N/A | Project Bridge: Peer Health Navigator Intervention | April 2014 | March 2020 |
| NCT00695708 | Completed | N/A | Training-induced Cerebral Reorganization in Schizophrenia | January 2008 | January 2010 |
| NCT02824055 | Completed | Phase 1 | A Study to Evaluate The Effects of RO5545965 in Participants With Negative Symptoms of Schizophrenia Treated With Antipsychotics | June 27, 2016 | April 24, 2017 |
| NCT01086748 | Completed | Phase 2 | A Study in Schizophrenia Patients | March 2010 | May 2012 |
| NCT00295139 | Completed | N/A | Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients | January 2005 | March 2010 |
| NCT03007628 | Completed | N/A | Magnetic Seizure Therapy Versus Electroconvulsive Therapy for Schizophrenia | October 2016 | July 2019 |
| NCT00046085 | Completed | N/A | Online Family Support and Education for Schizophrenia | March 2001 | November 2006 |
| NCT02975973 | Completed | N/A | Prefrontal Cortical Engagement Through Non-Invasive Brain Stimulation in Schizophrenia | November 2016 | June 2019 |
| NCT00597168 | Completed | Quality of Life in Schizophrenic Patients | October 2007 | October 2009 | |
| NCT03404219 | Completed | N/A | Motivation and Skills Support (MASS) | November 1, 2018 | May 11, 2020 |
| NCT02501109 | Completed | Phase 1 | Comparative Bioavailability Study of Aripiprazole 10 mg Oral Soluble Film vs Abilify® 10 mg Tablet in Healthy Volunteers | October 2015 | March 2016 |
| NCT01780116 | Completed | Phase 1/Phase 2 | Effectiveness of Adherence Therapy for Schizophrenia | May 2013 | February 2016 |
| NCT00061802 | Completed | Phase 4 | Efficacy and Safety of Two Atypical Antipsychotics vs. Placebo in Patients With an Acute Exacerbation of Either Schizophrenia or Schizoaffective Disorder | June 2003 | February 2004 |
| NCT00145847 | Completed | Phase 4 | Naltrexone Treatment of Alcohol Abuse in Schizophrenia | April 2003 | May 2008 |
| NCT04822051 | Completed | N/A | The Effect of Psychoeducation Based on Uncertainty In Illness Theory On Schizophrenia Caregivers | April 1, 2019 | August 31, 2020 |
| NCT04327843 | Completed | Phase 3 | Reducing the Burden of Chronic Psychotic Disorders in Tanzania (CAPACITY) | November 5, 2019 | July 30, 2020 |
| NCT01029769 | Completed | N/A | Efficacy of an Early Antipsychotic Switch in Case of Poor Initial Response to the Treatment of Schizophrenia | December 2009 | March 2015 |
| NCT02077829 | Completed | N/A | Implementation of Illness Management and Recovery in Mental Health Services | March 2014 | June 2015 |
| NCT03652974 | Completed | Phase 4 | Disturbance of Plasma Cytokine Parameters in Clozapine-Resistant Treatment-Refractory Schizophrenia (CTRS) and Their Association With Combination Therapy | September 6, 2018 | August 30, 2021 |
| NCT01006551 | Completed | Phase 2 | Ziprasidone in Early Onset Schizophrenia Spectrum Disorders | December 2002 | February 2006 |
| NCT01198353 | Completed | Phase 4 | Effectiveness of Ziprasidone for Patients With Schizophrenia | September 2010 | December 2013 |
| NCT01602029 | Completed | Phase 2 | Randomized Double Blind Placebo Control Study in Patients With Schizophrenia | August 2010 | June 2013 |
| NCT04712734 | Completed | Phase 1 | A Study to Evaluate Iloperidone Long-acting Injection (LAI) for the Treatment of Schizophrenia | January 13, 2021 | August 30, 2022 |
| NCT00105326 | Completed | Phase 2 | Trial Evaluating Paliperidone Extended-Release (ER) Tablets Versus Placebo on Sleep in Schizophrenia Patients | February 2005 | August 2005 |
| NCT00057135 | Completed | N/A | Improving Antipsychotic Adherence Among Patients With Serious Mental Illness | November 2002 | September 2006 |
| NCT00524043 | Completed | Phase 4 | An Efficacy and Safety Study of One Dosage of Paliperidone Extended Release (ER) in Treating Patients With Schizophrenia | September 2007 | November 2008 |
| NCT00548470 | Completed | Phase 4 | Varenicline Effects In Schizophrenic Smokers | June 2007 | December 2010 |
| NCT00001771 | Completed | I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers | May 1998 | May 2003 | |
| NCT01634542 | Completed | An Non-Interventional Study of Patients With Persistent Symptoms of Schizophrenia | February 2011 | December 2014 | |
| NCT03892876 | Completed | N/A | Trial of Stimulus-response Potentiation in Schizophrenia | September 1, 2019 | April 15, 2021 |
| NCT00946348 | Completed | Phase 1 | Cannabis and Schizophrenia: Self-Medication and Agonist Treatment | December 2009 | October 2012 |
| NCT00980252 | Completed | N/A | Medication Adherence in Schizophrenia: Development of a CBT-Based Intervention | November 2009 | March 2013 |
| NCT00845026 | Completed | Phase 2 | A Safety Study Comparing LY2140023 to Atypical Antipsychotic Standard Treatment in Schizophrenic Patients | March 2009 | December 2010 |
| NCT00042224 | Completed | Phase 1/Phase 2 | Electroconvulsive Therapy in Clozapine Refractory Schizophrenia | December 2000 | July 2008 |
| NCT01994473 | Completed | Phase 1 | Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects With Schizophrenia | October 2013 | December 2014 |
| NCT01397786 | Completed | Phase 3 | Safety and Tolerability Study of Oral OPC-34712 as Maintenance Treatment in Adults With Schizophrenia | September 2011 | January 2016 |
| NCT01493622 | Completed | Phase 4 | The Study of Minocycline for Negative and Cognitive Symptoms in Schizophrenia | June 2010 | December 2011 |
| NCT00697658 | Completed | INVISION - An Observational Study to Explore Effectiveness, Tolerability and Safety of Paliperidone ER in Patients With Schizophrenia | March 2008 | November 2009 | |
| NCT01104792 | Completed | Phase 3 | Long-term Study of Cariprazine in Patients With Schizophrenia | May 31, 2010 | January 31, 2013 |
| NCT01979679 | Completed | Phase 3 | A D2 Receptor Occupancy and fMRI Study in Schizophrenic Subjects Treated With Lurasidone | December 2008 | |
| NCT01699997 | Completed | Phase 2 | Oxytocin as Adjunctive Therapy for Schizophrenia | January 2014 | November 2015 |
| NCT01544608 | Completed | Observe Real-life Allocation of Atypical Antipsychotics in the Acute Inpatient Management of Schizophrenia | July 2012 | December 2012 | |
| NCT02224430 | Completed | Prediction of Relapse in Schizophrenia/Schizoaffective Disorder With Smartphones and On-body Sensors | August 2014 | December 31, 2019 | |
| NCT01952041 | Completed | N/A | A New Paradigm for Illness Monitoring and Relapse Prevention in Schizophrenia | March 13, 2015 | August 7, 2017 |
| NCT00650793 | Completed | Phase 3 | A 52-week, Open-label Extension Study Following a 6-week, Double-blind, Placebo- and Active- Controlled Study (R076477-SCH-303) to Evaluate the Safety and Tolerability of Paliperidone ER in Subjects With Schizophrenia | March 2004 | February 2006 |
| NCT00036361 | Completed | Phase 3 | Broad Effectiveness: Study With Aripiprazole | July 2002 | January 2003 |
| NCT00218231 | Completed | Phase 2 | Effect of Bupropion on Smoking Behavior in Smokers With Schizophrenia | January 2004 | August 2006 |
| NCT00210548 | Completed | Phase 3 | A Study to Evaluate the Effectiveness and Safety of 3 Doses of Paliperidone Palmitate in Treating Subjects With Schizophrenia | April 2005 | June 2006 |
| NCT00083668 | Completed | Phase 3 | Trial Evaluating Three Fixed Doses of Paliperidone Extended-Release (ER) Tablets and Olanzapine in the Treatment of Patients With Schizophrenia | April 2004 | May 2005 |
| NCT00043693 | Completed | N/A | Family Intervention for Mental Illness and Substance Abuse | April 2002 | December 2008 |
| NCT00488163 | Completed | Phase 4 | Pilot Study of Atomoxetine To Enhance COgnition In Patients With Schizophrenia | January 2005 | June 2007 |
| NCT02876900 | Completed | Phase 3 | Study to Assess Efficacy and Safety of HP3070 in Subjects Diagnosed With Schizophrenia. | August 2016 | June 2018 |
| NCT03370640 | Completed | Phase 1 | Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Japanese Male and Female Subjects With Schizophrenia in 2 Parts (Part 1 and 2). | November 29, 2017 | September 20, 2018 |
| NCT02824666 | Completed | Phase 1 | Study to Evaluate D2 Receptor Occupancy Following Single Intravenous Administration of ATI-9242 | June 20, 2016 | November 8, 2016 |
| NCT00232687 | Completed | Phase 4 | A Switch Study of BMS-337039 in Schizophrenic Out-patients | June 2005 | April 2007 |
| NCT03043820 | Completed | Phase 3 | Raloxifene Augmentation in Patients With a Schizophrenia Spectrum Disorder | August 2016 | July 1, 2021 |
| NCT02953639 | Completed | Phase 2 | A Study to Evaluate the Effects of Basmisanil in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS) Treated With Antipsychotics | November 30, 2016 | December 12, 2019 |
| NCT00108368 | Completed | Phase 4 | The Effects of Risperidone and Olanzapine on Thinking | October 2003 | March 2006 |
| NCT00431223 | Completed | N/A | Brain Activation Patterns in Schizophrenia After Computerized Cognitive Skills Training | September 2006 | September 2008 |
| NCT01479413 | Completed | Mitochondria and Schizophrenia: Effects of Antipsychotic Drugs | August 2009 | September 2013 | |
| NCT03390491 | Completed | N/A | OnTrack>An Online Role-Playing Game for Young People With First Episode Psychosis | November 1, 2018 | July 31, 2021 |
| NCT02634684 | Completed | Phase 2 | Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia. | July 1, 2014 | August 2020 |
| NCT00139919 | Completed | Phase 2 | Progressively Decreasing Titration Schedules of Bifeprunox in Subjects With Schizophrenia or Bipolar Disorder | January 2006 | October 2007 |
| NCT01926912 | Completed | A Study of Usage of Paliperidone Palmitate in Patients With Schizophrenia in a Hospital Setting | May 2013 | August 2014 | |
| NCT01926613 | Completed | N/A | Thinking Skills for Work in Severe Mental Illness | April 2006 | October 2011 |
| NCT02577575 | Completed | Early Phase 1 | Adult Oxytocin Study | August 2010 | November 2015 |
| NCT00222495 | Completed | N/A | A Comparative Study of New Medications for Psychosis in Adolescents | August 2002 | August 2006 |
| NCT05848700 | Completed | Phase 1 | A Clinical Study to Learn if SEP-363856 Has Physical Dependence in Adults With Schizophrenia | June 21, 2023 | March 15, 2024 |
| NCT01733602 | Completed | Phase 1/Phase 2 | tDCS to Enhance Cognitive Training in Schizophrenia | November 2012 | |
| NCT03899662 | Completed | N/A | Neurophysiological Evaluation of Schizophrenia Patients After Cognitive and Physical Intervention | November 30, 2018 | July 31, 2019 |
| NCT03497663 | Completed | N/A | VIA Family - Family Based Early Intervention Versus Treatment as Usual | September 25, 2017 | January 1, 2021 |
| NCT02748083 | Completed | N/A | Transcranial Direct Current Stimulation (tDCS) as a Treatment for Cognitive Deficits in Schizophrenic | December 1, 2015 | October 1, 2017 |
| NCT00001323 | Completed | Neuropsychiatric Evaluation of Healthy Volunteers and Adults With Schizophrenia | August 1992 | August 2005 | |
| NCT00004980 | Completed | Phase 2 | Repetitive Transcranial Magnetic Stimulation for "Voices" | December 1999 | June 2005 |
| NCT03359785 | Completed | Phase 2 | A Study to Evaluate Multiple Oral Doses of Luvadaxistat in Adults With Schizophrenia | January 10, 2018 | December 21, 2020 |
| NCT01959659 | Completed | A Non-Interventional Study of Patients With Persistent Symptoms of Schizophrenia to Describe Medical Resource Utilization and Burden of Illness | May 2013 | April 2014 | |
| NCT00216723 | Completed | Efficacy and Safety of Aripiprazole in Patients With Schizophrenia or Bipolar Disorder | April 2004 | December 2009 | |
| NCT02874560 | Completed | Evaluation of the Functional Remission Occurrence and Predictive Factors in Schizophrenia | August 12, 2014 | July 12, 2017 | |
| NCT05746455 | Completed | N/A | Motivation Skills Training for Schizophrenia | May 30, 2023 | December 31, 2023 |
| NCT00283517 | Completed | A Registry of Treatment Adherence for Patients With Schizophrenia | September 2003 | May 2006 | |
| NCT00584519 | Completed | Control of Metabolic and Cardiovascular Risk in Patients With Schizophrenia and Overweight | June 2007 | June 2009 | |
| NCT04325100 | Completed | N/A | Intervention Targeting Motivational Negative Symptoms | April 20, 2019 | February 27, 2020 |
| NCT00224380 | Completed | N/A | Medication Adherence in Older Adults With Serious Mental Illness | July 2003 | February 2005 |
| NCT01617187 | Completed | Phase 3 | A Study of the Efficacy and Safety of Asenapine in Participants With an Acute Exacerbation of Schizophrenia (P05688) | December 4, 2012 | September 9, 2014 |
| NCT01384604 | Completed | Neurophysiological Studies in Schizophrenia and Psychiatric Disorders | December 2007 | May 2013 | |
| NCT00231894 | Completed | Phase 4 | Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia | May 2005 | January 2010 |
| NCT00047450 | Completed | N/A | Antidepressant Treatment in Older Adults With Schizophrenia | September 2001 | September 2007 |
| NCT03143907 | Completed | N/A | Mindfulness Group-based Intervention for Early Psychosis | February 22, 2018 | May 31, 2020 |
| NCT01043458 | Completed | Phase 1 | Pharmacokinetic Study of ABT-126 in Stable Subjects With Schizophrenia | November 2009 | |
| NCT01555697 | Completed | Phase 1/Phase 2 | Biomarker Strategies for Medication-Enhanced Cognitive Training in Schizophrenia | July 2014 | June 1, 2019 |
| NCT00539071 | Completed | Phase 4 | High Dose Risperidone Consta for Patients With Schizophrenia With Poor Response to Risperidone | March 2008 | May 2012 |
| NCT02539797 | Completed | N/A | Improving Cognition in Schizophrenia Using tDCS | October 2014 | October 2016 |
| NCT01192867 | Completed | Phase 3 | A Study of RO4917838 in Participants With Persistent, Predominant Negative Symptoms of Schizophrenia (NN25310) | December 11, 2010 | May 26, 2014 |
| NCT01170689 | Completed | The Prevalence of Obesity For Schizophrenia Inpatients in Taiwan | March 2010 | March 2010 | |
| NCT02697045 | Completed | Phase 4 | Effects of Aripiprazole (LAI) on Phychosocial/Cognitive Functioning, pt Reported AcceptabilityofTreatment in Sch | January 4, 2017 | March 31, 2018 |
| NCT02477670 | Completed | Phase 2 | Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Residual Schizophrenia | September 2015 | July 21, 2017 |
| NCT01269710 | Completed | Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study | October 2009 | March 2011 | |
| NCT00640562 | Completed | Phase 3 | Quetiapine Extended Release Depression Symptoms | February 2008 | February 2010 |
| NCT03485131 | Completed | N/A | Transcranial Direct-current Stimulation (tDCS) in Treatment Refractory Auditory Hallucinations | April 2014 | March 2018 |
| NCT02281162 | Completed | The Influence of Vitamin D on Atypical Antipsychotic-induced Weight Gain | November 2014 | September 2015 | |
| NCT01696929 | Completed | Phase 1 | An Open-Label Trial of Tocilizumab in Schizophrenia | September 2012 | December 2014 |
| NCT03526354 | Completed | Phase 4 | Controlled Trial of Brexpiprazole For The Treatment of Co-occurring Schizophrenia and Substance Use Disorder | March 19, 2018 | February 29, 2024 |
| NCT01524380 | Completed | N/A | Ginkgo Biloba Extract for Schizophrenia | September 2011 | August 2013 |
| NCT00692133 | Completed | Spanish Validation of Tool Questionnaire to Assess Patients´Perception About Antipsychotic Treatment | March 2008 | August 2008 | |
| NCT00216632 | Completed | Phase 4 | A Study of Treatment Success in Changing From Olanzapine to Long-acting Injectable Risperidone (RISPERDAL® CONSTA™) | March 2005 | July 2007 |
| NCT00319904 | Completed | The Partners Genetics Collaborative Study of Schizophrenia | March 2001 | October 2017 | |
| NCT03880227 | Completed | N/A | Improving Visual Attention in Schizophrenia | March 25, 2019 | March 4, 2020 |
| NCT01213524 | Completed | Phase 2 | Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia | September 2005 | March 2011 |
| NCT00073164 | Completed | Phase 2 | Depakote ER Plus an Atypical Antipsychotic Vs. an Atypical Antipsychotic Alone in the Treatment of Schizophrenia | July 2003 | |
| NCT04940039 | Completed | Phase 4 | A Study to Assess the Treatment of Schizophrenia With Paliperidone Palmitate in Rwandan Healthcare Settings | July 22, 2021 | April 16, 2024 |
| NCT04325737 | Completed | Phase 1 | Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Japanese Male and Female Subjects With Schizophrenia | March 31, 2020 | August 7, 2020 |
| NCT00573417 | Completed | Phase 4 | A Placebo-Controlled Trial of Modafinil (Provigil) Added to Clozapine in Patients With Schizophrenia | September 2003 | November 2007 |
| NCT03050853 | Completed | N/A | The Appeal and Impact of E-cigarettes in Smokers With SMI | March 1, 2017 | January 31, 2021 |
| NCT00466310 | Completed | Phase 1 | Metabolic Signatures and Biomarkers in Schizophrenia | February 2007 | January 2011 |
| NCT00330551 | Completed | Phase 4 | Oral Versus Injectable Risperidone for Treating First-Episode Schizophrenia | March 2006 | November 2012 |
| NCT01169142 | Completed | Phase 4 | Study of Vitamin D in the Severely Mentally Ill | January 2010 | December 2015 |
| NCT01214135 | Completed | A Retrospective Non-interventional Study to Evaluate the Use of Seroquel Extended Release (XR) and Immediate Release (IR) in the Clinical Practice of Inpatients With Schizophrenia | October 2010 | December 2010 | |
| NCT01425671 | Completed | Neural Oscillations as Genetic and Functional Biomarkers in Normal and Disease States | November 30, 2010 | January 2024 | |
| NCT00018642 | Completed | N/A | Quetiapine vs Haloperidol Decanoate for the Long Term Treatment of Schizophrenia and Schizoaffective Disorder | April 1997 | March 2002 |
| NCT01125267 | Completed | N/A | Promoting Adherence to Treatment in Schizophrenia | April 2003 | October 2008 |
| NCT01866098 | Completed | N/A | Naltrexone for Antipsychotic-Induced Weight Gain | May 2013 | April 7, 2019 |
| NCT01534936 | Completed | Atypical Antipsychotics in the Treatment of Affective Symptoms of Schizophrenia in Hungary | February 2012 | December 2012 | |
| NCT03304457 | Completed | Phase 4 | Lurasidone Vs Olanzapine on Neurotrophic Biomarkers and Cardiometabolic Parameters in Unmedicated Schizophrenia | August 25, 2017 | March 25, 2018 |
| NCT03669250 | Completed | Phase 1 | CVN058 Effect on Mismatch Negativity in Schizophrenics | November 9, 2018 | March 6, 2020 |
| NCT00086593 | Completed | Phase 3 | Study Of An FDA-approved Drug As Additional Therapy In Patients With Schizophrenia | May 2004 | July 2005 |
| NCT00639483 | Completed | Phase 2 | Efficacy and Safety of Celecoxib as Add-on Therapy to Risperidone Versus Risperidone Alone in Patients With Schizophrenia | March 2003 | January 2004 |
| NCT04611737 | Completed | N/A | Self-Determination Theory and Motivational Interviewing | November 3, 2020 | May 24, 2023 |
| NCT03260257 | Completed | N/A | A Neurofeedback Intervention to Improve Working Memory in Schizophrenia | March 1, 2018 | April 1, 2024 |
| NCT01542229 | Completed | N/A | PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness) | May 3, 2012 | December 31, 2016 |
| NCT01955564 | Completed | Phase 1 | A Phase I- Sequential Cohort Dosing to Determine Maximum Tolerated Dose in Healthy Male Volunteers. | June 2013 | February 2015 |
| NCT01914393 | Completed | Phase 3 | Pediatric Open-Label Extension Study | September 30, 2013 | October 17, 2018 |
| NCT00234377 | Completed | Phase 3 | Seroquel Switching Study: Feasibility of Switching Any Antipsychotic Treatment to Seroquel in Patients With Schizophrenia | November 2004 | May 2006 |
| NCT00001320 | Completed | Neuroimaging of Dopamine Metabolism in Normal and Psychiatric Patients | October 1991 | July 2003 | |
| NCT00796835 | Completed | Phase 1 | A Dose-proportionality Study of Five Tablet Strengths of ER OROS Paliperidone | July 2004 | October 2004 |
| NCT03757988 | Completed | N/A | Targeting Physical Health in Schizophrenia: Physical Activity Can Enhance Life | December 6, 2018 | September 11, 2019 |
| NCT00498550 | Completed | Phase 4 | Treatment of Schizophrenia and Comorbid Cannabis Use Disorder: Comparing Clozapine to Treatment-as-Usual | October 2000 | March 2009 |
| NCT01967667 | Completed | N/A | Biological Evaluation of Dietary Supplement Liposomal Glutathione | April 2014 | February 2021 |
| NCT04673851 | Completed | N/A | Horyzons: Implementation in Clinical Practice | January 19, 2021 | August 31, 2023 |
| NCT03854409 | Completed | Phase 1 | A Trial of Single- and Multiple-doses of Aripiprazole in Adult Subjects With Schizophrenia or Bipolar I Disorder | January 31, 2019 | February 20, 2020 |
| NCT00254202 | Completed | Phase 3 | Efficacy and Safety of Iloperidone Compared With Placebo and Active Control in Subjects With Acute Schizophrenia | November 2005 | March 2007 |
| NCT00400166 | Completed | N/A | Recovery Guide Intervention for Recurrent Psychiatric Hospitalization | December 2006 | May 2009 |
| NCT04432688 | Completed | The Safety and Effectiveness of Latuda® Post-marketing Surveillance in the Treatment of Chinese Schizophrenia Patients | December 1, 2020 | June 18, 2023 | |
| NCT04072354 | Completed | Phase 3 | A Clinical Trial to Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia | September 11, 2019 | September 12, 2023 |
| NCT01488929 | Completed | Phase 2 | Efficacy, Safety, and Tolerability of TC-5619 as Augmentation Therapy to Improve Negative Symptoms and Cognition in Outpatients With Schizophrenia | December 2011 | November 2013 |
| NCT02815813 | Completed | N/A | Lifestyle Intervention for Young Adults With Serious Mental Illness | July 3, 2017 | May 31, 2022 |
| NCT04268303 | Completed | Phase 3 | Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia | January 24, 2020 | May 6, 2020 |
| NCT02166918 | Completed | Factors Influencing Social Functioning of People With Schizophrenia | June 2013 | July 2016 | |
| NCT02420015 | Completed | Phase 4 | Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia | March 27, 2017 | January 24, 2019 |
| NCT03882619 | Completed | N/A | Effectiveness of Using Calligraphic Activity to People With Schizophrenia | April 1, 2019 | November 30, 2020 |
| NCT01795326 | Completed | Physician Survey on Monitoring of Patients Treated With Quetiapine | June 2013 | September 2013 | |
| NCT02032680 | Completed | N/A | Comparison of E-health vs. In-person Multi-Family Group (MFG) | August 19, 2015 | September 30, 2018 |
| NCT02287584 | Completed | Phase 3 | Confirmatory Study of DSP-5423P in Patients With Schizophrenia | December 2014 | December 2018 |
| NCT00305422 | Completed | Phase 3 | Effect of Quetiapine on Negative Symptoms and Cognition | November 2001 | January 2003 |
| NCT01479400 | Completed | Effects of Exposed to Antipsychotics Throughout Pregnancy on Infants Development: A Prospective Study | October 2007 | May 2011 | |
| NCT04176835 | Completed | N/A | Oxytocin and Social Decision Making in Schizophrenia | April 2016 | September 2019 |
| NCT00540267 | Completed | Bone Density in Patients With Schizophrenia | November 2007 | November 2008 | |
| NCT00224822 | Completed | Phase 4 | The Effects of Aripiprazole on Patients With Metabolic Syndrome | March 2004 | March 2007 |
| NCT03847753 | Completed | Exploring the Comorbidity Between Mental Disorders and General Medical Conditions | January 1, 2000 | January 31, 2020 | |
| NCT01634373 | Completed | Phase 1 | Steady State Bioequivalence Study of Torrent Pharmaceuticals Ltd's Bioequivalence Study of Torrent Pharmaceuticals Ltd's Quetiapine Tablets | ||
| NCT02573701 | Completed | N/A | Guideline vs Usual Treatment in Schizophrenic Adolescents | October 2011 | July 2015 |
| NCT00419146 | Completed | Phase 2/Phase 3 | Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants | September 2001 | April 2004 |
| NCT00455663 | Completed | N/A | Cognitive Adaptive Training for Improving Medication Adherence, Symptoms, and Function in People With Schizophrenia | November 2000 | January 2006 |
| NCT03919994 | Completed | Observational Study of Long Acting Injectable Medications (LAIs) in Schizophrenia (OASIS) | March 28, 2019 | January 4, 2023 | |
| NCT00391261 | Completed | Phase 4 | An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications. | July 2006 | October 2007 |
| NCT01592110 | Completed | Phase 1 | A Safety and PK Study of Injectable Risperidone-SABER and the DosePro Delivery System in Patients With Schizophrenia | July 2012 | April 2013 |
| NCT00224276 | Completed | Prevalence of Diabetes Mellitus Among Patients Treated With Atypical and Conventional Antipsychotics | |||
| NCT03198078 | Completed | Phase 3 | Trial to Evaluate the Short-term Safety & Efficacy of Brexpiprazole Monotherapy in the Treatment of Adolescents With Schizophrenia | June 30, 2017 | April 3, 2023 |
| NCT03865186 | Completed | N/A | An Evaluation of a Psychoeducation Program in Individuals Diagnosed With Schizophrenia | January 1, 2015 | July 15, 2016 |
| NCT00535574 | Completed | Phase 3 | Bexarotene Augmentation of Antipsychotic Treatment for Chronic Schizophrenia | November 2008 | May 2011 |
| NCT00132314 | Completed | Phase 3 | Long-Acting Injectable Risperidone in the Treatment of Schizophrenia | September 2006 | September 2009 |
| NCT00992407 | Completed | Phase 4 | An Efficacy and Safety Study of Long Acting Injectable Risperidone and Oral Risperidone in Participants With Schizophrenia or Schizoaffective Disorder | December 2007 | December 2010 |
| NCT00796640 | Completed | Phase 1 | A Pharmacokinetics and Pharmacodynamics Study Under Fasting and Fed Conditions With Paliperidone Extended-release and Immediate-release Formulations | September 2003 | November 2003 |
| NCT00791284 | Completed | Phase 1 | A Study of the Pharmacokinetics of Paliperidone in Volunteers With Normal or Impaired Liver Function | August 2004 | December 2004 |
| NCT00518323 | Completed | Phase 3 | A Double-blind, Placebo-controlled Study of the Safety and Efficacy of Paliperidone Extended Release (ER) in the Treatment of Schizophrenia in Adolescent Patients | August 2007 | March 2009 |
| NCT01015001 | Completed | Phase 3 | A Pilot Double-blind Sham-controlled Trial of Repetitive Transcranial Magnetic Stimulation for Patients With Refractory Schizophrenia Treated With Clozapine | May 2008 | December 2009 |
| NCT01451164 | Completed | Phase 2/Phase 3 | A Dose-finding Trial of OPC-34712 in Patients With Schizophrenia | October 2011 | |
| NCT01876056 | Completed | N/A | Brief Culturally Adapted Cognitive Behavior Therapy for Psychosis | February 2013 | July 2014 |
| NCT00791713 | Completed | Phase 1 | A Study of the Effects of Paroxetine on the Pharmacokinetics of Paliperidone ER | March 2006 | July 2006 |
| NCT01031563 | Completed | Risk Perception in Drug-Dependent Adults With and Without Schizophrenia | August 18, 2009 | May 3, 2012 | |
| NCT01716975 | Completed | Phase 3 | Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy | October 2012 | February 2016 |
| NCT05739344 | Completed | N/A | The Effect of Developing Psychological Resilience on Functionality in Schizophrenia Patients | February 1, 2022 | March 1, 2023 |
| NCT00566631 | Completed | Phase 3 | An Efficacy and Safety Study of Paliperidone Extended-Release (ER) Tablets in Participants With Schizophrenia | July 2007 | May 2009 |
| NCT01244828 | Completed | Phase 3 | Long-term Study of Asenapine in Participants With Residual Subtype, Receiving Multiple or/and High Dose Drugs, or Treatment Refractory Schizophrenia (P06238) | April 5, 2011 | August 21, 2014 |
| NCT05628103 | Completed | Phase 3 | A Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia That Switch to SEP-363856 From Their Current Antipsychotic Medication | December 19, 2022 | April 1, 2024 |
| NCT01149655 | Completed | Phase 3 | Efficacy & Safety Study of Oral Aripiprazole in Adolescents With Schizophrenia | July 2011 | December 2013 |
| NCT02974400 | Completed | N/A | Evaluation of Internet-based Cognitive Behavioral Self-help Treatments for People With Psychosis | December 6, 2016 | April 16, 2019 |
| NCT04011280 | Completed | Phase 4 | Novel Pharmacotherapy Approaches in Smokers With Serious Mental Illness | August 12, 2019 | March 4, 2022 |
| NCT02901015 | Completed | N/A | Evaluation and Validation of Social Cognition Battery to Characterize Schizophrenic Patients Functioning | April 2013 | December 2017 |
| NCT02341131 | Completed | N/A | Cognitive Remediation Therapy in Schizophrenia: Effects on BDNF Levels | January 2012 | March 2016 |
| NCT03409393 | Completed | N/A | Feasibility and Relevance of High-Intensity Functional Training in Patients With First-Episode Psychosis | January 22, 2018 | August 1, 2018 |
| NCT02334228 | Completed | N/A | Evaluation of the In SHAPE Fitness Intervention for Adults With Serious Mental Illness | September 2006 | August 2009 |
| NCT00369577 | Completed | Phase 2 | Staccato Loxapine in Agitation (Proof of Concept) | August 2006 | January 2007 |
| NCT01037075 | Completed | Influence of Nicotine on Cognitive Function in Schizophrenic Patients With and Without Comorbid Drug Dependence | May 14, 2006 | January 22, 2013 | |
| NCT01794429 | Completed | Phase 3 | Treatment of Antipsychotic-associated Obesity With a GLP-1 Analogue | February 2013 | June 2015 |
| NCT03571685 | Completed | N/A | Sustainable Early Episode Clinic Study (SEEC) | January 31, 2017 | December 20, 2019 |
| NCT00245674 | Completed | Phase 4 | SOLIACS: Solian Solution in the Acute Setting | June 2005 | |
| NCT01034085 | Completed | Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia | June 2, 2009 | June 11, 2013 | |
| NCT00818298 | Completed | N/A | 24-Hour Time Course of Striatal Dopamine D2 Receptor Occupancy of Ziprasidone: A PET Study | January 2009 | June 2011 |
| NCT00634348 | Completed | Phase 4 | A Study Comparing the Efficacy and Safety of Ziprasidone and Aripiprazole for the Treatment fo Schizophrenia or Schizoaffective Disorder in Hospitalized Patients | April 2004 | March 2005 |
| NCT05281640 | Completed | N/A | Psychological Interventions for Complex PTSD And Schizophrenia-Spectrum Disorder: PICASSO Trial | February 28, 2022 | August 31, 2023 |
| NCT00192855 | Completed | N/A | Entacapone Augmentation for Schizophrenia | June 2003 | October 2006 |
| NCT00870909 | Completed | N/A | Transcranial Direct Current Stimulation (tDCS) and Hallucinations in Schizophrenia | February 2, 2009 | July 20, 2016 |
| NCT00237848 | Completed | Phase 3 | D-Serine for Enhancing Cognitive Retraining for the Treatment of Schizophrenia | February 2005 | |
| NCT01595698 | Completed | N/A | Schizophrenia and Physical Exercise | February 2010 | December 2010 |
| NCT00090012 | Completed | Phase 4 | Comparison of Continuing Olanzapine to Switching to Quetiapine in Overweight or Obese Patients With Schizophrenia and Schizoaffective Disorder | July 2004 | March 2006 |
| NCT00184379 | Completed | N/A | Effects of Psychoeducation of Relatives to Patients With Serious Mental Illness | April 2005 | June 2010 |
| NCT05954208 | Completed | N/A | Vısual Arts Group Therapy Based On Watson's Human Care Model In Indıvıduals Wıth Schızophrenıa | December 14, 2022 | June 1, 2023 |
| NCT03150771 | Completed | Phase 1 | Study to Determine the Pharmacokinetics, Safety & Tolerability of Aripiprazole in Adults With Schizophrenia | June 14, 2017 | May 2, 2018 |
| NCT01677377 | Completed | Phase 2 | Multiple Ascending Dose Study of the Safety, Tolerability, Pharmacokinetic/Efficacy | August 2012 | April 2013 |
| NCT00288366 | Completed | N/A | Anticonvulsant Mood Stabilizers, Antipsychotic Drugs and the Insulin Resistance Syndrome | January 2006 | December 2008 |
| NCT01869660 | Completed | Phase 2/Phase 3 | Shared Decision Making for Patients With First-admission Schizophrenia | June 2013 | October 2015 |
| NCT05115604 | Completed | N/A | Insomnia in the Patient With Schizophrenic Disorder: Evaluation of a CBT and Psychoeducational Intervention | April 8, 2021 | July 9, 2022 |
| NCT00981123 | Completed | Non-interventional (NI) Study to Observe Efficacy and Usage of Quetiapine in Acute Episodes of Schizophrenia and as Maintenance Therapy Following Standard Clinical Practice in Croatia | September 2009 | April 2010 | |
| NCT00144027 | Completed | N/A | Patient-Centered Medication Adherence Intervention for Schizophrenia | December 2004 | July 2009 |
| NCT00650429 | Completed | Phase 4 | A Study of the Efficacy and Safety of Ziprasidone for the Treatment of Acute Exacerbation of Schizophrenia or Schizoaffective Disorder | October 2003 | May 2005 |
| NCT00184418 | Completed | The Immune System and Psychiatric Disorders | January 2005 | January 2008 | |
| NCT00589914 | Completed | Phase 3 | Comparison of Paliperidone Palmitate and RISPERDAL CONSTA in Patients With Schizophrenia | March 2007 | June 2009 |
| NCT05663749 | Completed | Phase 4 | Topiramate vs Metformin on Cardio-Metabolic Profile in Schizophrenia on Atypical Antipsychotics | September 20, 2022 | August 20, 2023 |
| NCT00248794 | Completed | N/A | Cognitive Rehabilitation in Schizophrenia | June 2004 | October 2009 |
| NCT01391403 | Completed | Phase 3 | Artemisinin With Risperidone for First-Episode and Drug-Naive Schizophrenia | September 2008 | May 2011 |
| NCT03217357 | Completed | N/A | tDCS, Stress and Risk for Schizophrenia | May 2, 2019 | July 31, 2023 |
| NCT00666146 | Completed | Familial Schizophrenia and Spectrum Personality Disorders | July 2004 | January 2020 | |
| NCT02334280 | Completed | N/A | Evaluation of A Statewide Program to Prevent Early Mortality and to Promote Fitness in Persons With SMI | September 2009 | May 2013 |
| NCT00001656 | Completed | Phase 4 | Comparison of Clozapine vs Olanzapine in Childhood-Onset Psychotic Disorders | June 1997 | June 2008 |
| NCT00013000 | Completed | N/A | A Multi-Site Study of Strategies for Implementing Schizophrenia Guidelines | September 2000 | |
| NCT01009060 | Completed | Phase 2 | Study to Evaluate the Efficacy and Safety of GSK239512 in Schizophrenia | December 1, 2009 | August 10, 2011 |
| NCT00828958 | Completed | Phase 3 | Injection Site Tolerability of Multiple Dose Treatment With Long-acting Injectable Risperidone Administered Via Deltoid Muscle in Chronic Schizophrenia Patients. | February 2006 | September 2006 |
| NCT00563706 | Completed | Phase 2 | Study Evaluating Vabicaserin in Subjects With Schizophrenia | December 2007 | June 2008 |
| NCT01361698 | Completed | N/A | Illness Management and Recovery (IMR) in Danish Community Mental Health Centres | February 2011 | December 2014 |
| NCT00774085 | Completed | An Observational Study to Assess Treatment & Outcomes Data in Patients Receiving Long-Acting Injectable Risperidone | November 2004 | December 2007 | |
| NCT01805128 | Completed | N/A | Exploration of the Social Cognition in Adolescents With a Dissociative Disorder or Autism Spectrum | January 2013 | May 2013 |
| NCT00892489 | Completed | Phase 1 | A Bioequivalence Study of 15 mg ER OROS Paliperidone | July 2004 | December 2004 |
| NCT03370341 | Completed | N/A | Stimulating the Brain to Improve Self-Awareness | December 1, 2017 | December 1, 2019 |
| NCT01292577 | Completed | Phase 1/Phase 2 | Adapted Cognitive/Affective Remediation for Cannabis Misuse in Schizophrenia | September 2010 | September 2014 |
| NCT01161277 | Completed | Phase 4 | Effects of Aripiprazole and Haloperidol on Mesolimbic System Functioning | August 2010 | June 2011 |
| NCT02400502 | Completed | N/A | Integrated Coping and Awareness Training | March 2015 | April 2016 |
| NCT04158687 | Completed | Phase 2 | A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia | November 26, 2019 | December 22, 2020 |
| NCT00178971 | Completed | Phase 3 | Serotonin 1A Agonists and Cognition in Schizophrenia | January 2003 | October 2004 |
| NCT04002258 | Completed | Prolactin Change in Chinese Patients With Schizophrenia After Antipsychotics Treatment | June 6, 2019 | October 25, 2022 | |
| NCT00373672 | Completed | Phase 4 | Effects of Armodafinil on Cognition for Patients With Schizophrenia or Schizoaffective Disorder | August 2006 | January 2010 |
| NCT00444028 | Completed | Phase 1 | Staccato Loxapine Single Dose PK | September 2005 | November 2005 |
| NCT00728195 | Completed | Phase 2 | An Efficacy and Safety Study of 3 Fixed Doses of JNJ-37822681 in Participants With Schizophrenia | November 2008 | February 2010 |
| NCT01189006 | Completed | Phase 2/Phase 3 | Add-On Therapy to Risperidonein Schizophrenia | January 2005 | December 2008 |
| NCT00034775 | Completed | Phase 3 | A Study to Assess Safety and Tolerabiltiy Associated With a Switch From Oral Antipsychotic Medications to Long-acting Injectable Risperidone in Patients With Schizophrenia. | August 2001 | October 2002 |
| NCT01786369 | Completed | Adherence in Patients Admitted to a Psychiatric Unit for Acute Psychosis: an Analysis of Serum Levels of Antipsychotics. | February 2013 | April 2015 | |
| NCT06041646 | Completed | Phase 4 | Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder | October 12, 2023 | April 29, 2024 |
| NCT00102063 | Completed | Phase 3 | Aripiprazole in Adolescents With Schizophrenia | July 2004 | August 2006 |
| NCT02748694 | Completed | Phase 1 | Phase 1 TAK-041 First-in-Human Safety, Tolerability, and Pharmacokinetics Study | May 9, 2016 | September 22, 2019 |
| NCT05245539 | Completed | Phase 1 | Trial to Study the Effect of CVL-231 on 24-Hour Ambulatory Blood Pressure in Participants With Schizophrenia | January 24, 2022 | November 14, 2022 |
| NCT02009826 | Completed | Psychosis-Associated Neuroinflammation in Schizophrenia | November 2013 | February 2017 | |
| NCT01726335 | Completed | Phase 4 | Switching From Oral Antipsychotics to Long-Acting Risperidone in Participants With Schizophrenia | January 2006 | March 2008 |
| NCT00448630 | Completed | An Observational Study On Metabolic Syndrome Parameters In Schizophrenia Patients Treated With Atypical Antipsychotics | October 23, 2007 | July 30, 2008 | |
| NCT00877552 | Completed | Prospective Studies of the Pathogenesis of Schizophrenia | August 2002 | December 2019 | |
| NCT02037074 | Completed | Phase 1 | Study to Assess the Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Effects of EVP-6308 and the Potential of EVP-6308 to Affect the PK Properties of the Antipsychotic Regimen in Subjects With Schizophrenia Currently Receiving Stable Treatment With up to 2 Atypical Antipsychotics | June 2014 | |
| NCT00458211 | Completed | Phase 4 | Efficacy and Tolerability of Switching to Ziprasidone From Other Antipsychotics | May 2005 | April 2008 |
| NCT04092686 | Completed | Phase 3 | A Clinical Trial That Will Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia | September 30, 2019 | June 14, 2023 |
| NCT00456976 | Completed | Early Phase 1 | Efficacy of Selegiline in Negative Symptoms of Schizophrenia | April 2007 | September 2007 |
| NCT00825539 | Completed | Phase 1/Phase 2 | Pharmacodynamic/Pharmacokinetic Study of AQW051 in Schizophrenia | January 2009 | November 2011 |
| NCT04040998 | Completed | N/A | Compensatory Cognitive Training For Schizophrenia | January 5, 2018 | May 31, 2018 |
| NCT05106309 | Completed | Phase 1 | Pharmacokinetics of CVL-231 Following Single Oral Administration of Modified- and Immediate-release Formulations in Fasted and Fed Healthy Participants | December 29, 2021 | February 24, 2022 |
| NCT00458107 | Completed | Phase 1 | Study Evaluating the Safety and Tolerability of SCA-136 in Healthy Japanese and Non-Japanese Female Subjects | April 2007 | September 2007 |
| NCT00370500 | Completed | Phase 4 | Quetiapine and the Dopaminergic Epigenetic Control | April 2007 | July 2008 |
| NCT00265343 | Completed | Phase 3 | 6-Month Extension Trial of Asenapine With Olanzapine in Negative Symptom Patients Who Completed the Protocol 25543 (25544)(P05777) | December 2005 | January 2008 |
| NCT00005658 | Completed | Phase 2 | Glycine to Treat Psychotic Disorders in Children | May 2000 | January 2002 |
| NCT05936983 | Completed | Comparison of Physical Fitness, Physical Activity Level in Patients With Bipolar Disorder and Schizophrenia | June 2, 2023 | June 20, 2023 | |
| NCT01400477 | Completed | Phase 2 | Nicotinic Receptors and Schizophrenia | July 2011 | June 2015 |
| NCT05449977 | Completed | Evaluation of Physical Activity, Physical Fitness, and Quality of Life in Patients With Schizophrenia | July 6, 2022 | August 15, 2022 | |
| NCT00562926 | Completed | Single Nucleotide Polymorphism (SNP) in Schizophrenia and Schizophrenia Spectrum Disorders: a Population Association Analysis With Hong Kong Chinese | July 2004 | June 2006 | |
| NCT03697252 | Completed | Phase 2 | A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia | September 18, 2018 | September 4, 2019 |
| NCT00183443 | Completed | Phase 3 | Treatment of Mania Symptoms With Drug Therapy | February 2005 | November 2010 |
| NCT02087579 | Completed | Phase 1 | Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants | February 2014 | December 2014 |
| NCT02360319 | Completed | Phase 4 | Comparison of a Long-acting Injectable Antipsychotic vs Clinician's Choice Early in Treatment to Break the Cycle of Relapse in Early Phase Schizophrenics | December 11, 2014 | March 31, 2019 |
| NCT04191876 | Completed | N/A | Financial Incentives to Improve Medication Adherence | November 1, 2019 | March 2, 2022 |
| NCT00918021 | Completed | Phase 4 | Polypharmacy in Clozapine-resistant Schizophrenia | June 2009 | July 2010 |
| NCT01655368 | Completed | N/A | Group Intervention for Improving Stigma Coping and Empowerment of People With Mental Illness (STEM) | May 2012 | June 2015 |
| NCT02921243 | Completed | Schizophrenia and the Gut Microbiome | October 1, 2016 | June 18, 2019 | |
| NCT00507988 | Completed | N/A | Complex Problem Solving Training in Schizophrenic Patients | August 2007 | February 2009 |
| NCT00119756 | Completed | Phase 3 | A Safety and Tolerability Study of Paliperidone Palmitate Injected in the Shoulder or the Buttock Muscle in Patients With Schizophrenia | June 2005 | November 2006 |
| NCT03345979 | Completed | Phase 3 | A Study of Aripiprazole Lauroxil or Paliperidone Palmitate for the Treatment of Schizophrenia | November 15, 2017 | March 12, 2019 |
| NCT00168311 | Completed | N/A | A Double-Blind Placebo Controlled Trial of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Negative Symptoms in Schizophrenia | August 2002 | July 2007 |
| NCT01394601 | Completed | A Study to Observe Real-life Allocation of Antipsychotics in Acute Inpatient Management of Schizophrenia | August 2011 | December 2011 | |
| NCT03056781 | Completed | N/A | Emotional Response in Psychiatric and Control Participants | February 15, 2017 | August 1, 2018 |
| NCT04605393 | Completed | N/A | Does Cannabidiol Attenuate the Acute Effects of ∆9-tetrahydrocannabinol Intoxication in Individuals Diagnosed With Schizophrenia? A Double-blind, Randomised, Placebo-controlled Experimental Study | January 1, 2021 | July 7, 2023 |
| NCT01678755 | Completed | Phase 2 | A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia | August 2012 | March 2014 |
| NCT02832037 | Completed | Phase 2 | Clinical Trial of BI 425809 Effect on Cognition and Functional Capacity in Schizophrenia | July 25, 2016 | January 29, 2020 |
| NCT00816894 | Completed | Phase 2 | D-serine Monotherapy for Schizophrenia | January 2009 | February 2013 |
| NCT02810964 | Completed | Phase 2 | Sulforaphane to Reduce Symptoms of Schizophrenia | February 22, 2017 | November 11, 2019 |
| NCT00827840 | Completed | Phase 4 | Paliperidone Extended-Release (ER) Versus Risperidone for Neurocognitive Function in Patients With Schizophrenia | November 2008 | February 2011 |
| NCT01514682 | Completed | N/A | Anti-Inflammatory Treatment of Schizophrenia | June 2012 | April 17, 2017 |
| NCT04588129 | Completed | Phase 1 | Receptor Occupancy of LB-102 Using Positron Emission Tomography (PET) in Healthy Volunteers | January 5, 2021 | November 15, 2021 |
| NCT00514449 | Completed | Phase 2 | Systematic Evaluation of Antiviral Medication in Schizophrenia | June 2007 | September 2016 |
| NCT00497848 | Completed | N/A | The Compliance Project Concerning People With Schizophrenia | May 2007 | July 2009 |
| NCT00018837 | Completed | N/A | Brief Hospitalization for Schizophrenia: Strategies to Improve Treatment Outcome | April 1998 | March 2001 |
| NCT00253240 | Completed | Diabetes Screening, Risk Management and Disease Management in a High-Risk Mental Health Population | September 2004 | September 2005 | |
| NCT01035996 | Completed | Dopamine Function and Reward Processing In Schizophrenia | March 8, 2005 | February 13, 2017 | |
| NCT02013622 | Completed | Phase 3 | Monotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Early-Episode Schizophrenia | November 2013 | October 2014 |
| NCT04025502 | Completed | Event-Related Potential (ERP) Biomarkers in Subjects With Schizophrenia and Healthy Volunteer Subjects | October 7, 2019 | January 31, 2021 | |
| NCT02176044 | Completed | Phase 1 | The Effect of Nitric Oxide on Spatial Working Memory in Patients With Schizophrenia - Pilot Study | August 2014 | February 2016 |
| NCT01029067 | Completed | N/A | Metacognitive Training in Schizophrenia | September 2009 | December 2013 |
| NCT01636037 | Completed | Phase 2 | Antipsychotic Augmentation With L-Dopa | September 2012 | January 2016 |
| NCT00823199 | Completed | N/A | An Open Trial of Allopurinol in Patients With Poorly Responsive Schizophrenia | November 2005 | August 2008 |
| NCT00791622 | Completed | Phase 1 | A Study of QT and QTc Intervals in Patients Administered Extended Release Paliperidone or Quetiapine | January 2006 | June 2006 |
| NCT04280367 | Completed | Learning and Executive Function Disorders in Children and Psychosis Risk at Adult-age | January 28, 2020 | May 29, 2020 | |
| NCT02534363 | Completed | Phase 4 | Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: 1-year Follow-up | October 2005 | January 2013 |
| NCT03183947 | Completed | N/A | Symptom Based Treatment Affects Brain Plasticity - Cognitive Training in Patients With Affective Symptoms | August 29, 2017 | December 6, 2019 |
| NCT00334035 | Completed | Phase 4 | Antipsychotic Therapy and First Episode | August 2003 | June 2007 |
| NCT00392743 | Completed | A Study to Compare Two Different Brain Imaging Techniques in Healthy Volunteers and in Schizophrenic Patients | December 2006 | May 2007 | |
| NCT01575912 | Completed | Past Pain Experience and Perception of Experimental Pain | March 2012 | January 2014 | |
| NCT00430391 | Completed | N/A | Comparison of Video Consent Versus Routine Consent for Participation in Research Studies | December 2003 | February 2010 |
| NCT04252131 | Completed | Phase 1 | Therapeutic Effect of Cassia Seed in Obesity of Patients With Schizophrenia | May 17, 2018 | October 31, 2019 |
| NCT02626832 | Completed | N/A | Regulation of Arginine-vasopressin (AVP) | February 2010 | December 2014 |
| NCT05784948 | Completed | N/A | Safety and Efficacy of Virtual Reality Mindfulness in Patients With Psychosis | April 8, 2020 | June 9, 2021 |
| NCT00657631 | Completed | N/A | Acceptance and Commitment Therapy for Delusions | April 2008 | June 2009 |
| NCT03355781 | Completed | Childhood Trauma in Schizophrenia: Exploration of Links Between Gene Expression, Cerebral Morphology and Symptomatology | November 14, 2018 | November 30, 2023 | |
| NCT03630822 | Completed | N/A | Multicenter, Randomized, Comparative and Prospective Study Evaluating the Impact on the Care Path of an Editorial Program Accompanied by Advance Directives in Psychiatry (DAP) for People Suffering From Schizophrenia, Bipolar I Disorder or Schizoaffective Disorder | January 2, 2019 | January 2, 2022 |
| NCT01561898 | Completed | Phase 3 | A Long-Term Study of JNS007ER in Patients With Schizophrenia | June 2006 | October 2008 |
| NCT02918825 | Completed | N/A | Long-acting Paliperidone Palmitate Injection and Olanzapine for Schizophrenia | September 1, 2016 | September 30, 2017 |
| NCT00237861 | Completed | Phase 4 | Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia | ||
| NCT03503318 | Completed | Phase 3 | Study to Evaluate TV-46000 as Maintenance Treatment in Adult and Adolescent Participants With Schizophrenia | April 27, 2018 | December 3, 2020 |
| NCT00876304 | Completed | Phase 1 | Multiple Dose Safety Study of PF-04802540 in Subjects With Schizophrenia | April 2009 | September 2009 |
| NCT01623713 | Completed | Phase 2 | Efficacy and Safety Study of Iloperidone Virus Risperidone to Treat Schizophrenia | June 2012 | November 2013 |
| NCT03623477 | Completed | N/A | Can Cognitive Training Decrease Reactive Aggression? | August 16, 2016 | October 25, 2019 |
| NCT00951418 | Completed | Serum Clozapine and Cognition | June 2009 | September 2013 | |
| NCT03874494 | Completed | Phase 3 | Safety and Efficacy of Brexpiprazole in the Treatment of Schizophrenia | November 27, 2019 | September 6, 2021 |
| NCT00177177 | Completed | N/A | L-carnosine for Schizophrenia | March 2004 | December 2007 |
| NCT00706654 | Completed | Phase 3 | Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia | September 2008 | August 2012 |
| NCT00430560 | Completed | Phase 2/Phase 3 | Work Activity Augmented by Cognitive Rehabilitation for Schizophrenia | October 2000 | October 2015 |
| NCT00295048 | Completed | N/A | Cognitive Remediation for Schizophrenia | November 2004 | May 2007 |
| NCT02709733 | Completed | N/A | Virtual Rehabilitation for the Treatment of Motivational Deficits in Schizophrenia | January 2016 | August 2018 |
| NCT00203788 | Completed | Phase 4 | Improving Work Outcome in People With Recent-onset Schizophrenia | May 1999 | December 2006 |
| NCT00960375 | Completed | Phase 2/Phase 3 | Smoking Cessation for Veterans With Severe and Persistent Mental Illness | April 2010 | December 2014 |
| NCT00501618 | Completed | Phase 4 | Equivalence of Generic Clozapine to Orally Dissolving Clozapine in Schizophrenia or Schizoaffective Disorder | November 2006 | July 2009 |
| NCT00078039 | Completed | Phase 3 | Trial Evaluating Three Fixed Dosages of Paliperidone Extended-Release (ER) Tablets and Olanzapine in the Treatment of Patients With Schizophrenia | March 2004 | January 2005 |
| NCT03197168 | Completed | N/A | Psychosocial Intervention to Reduce Self-stigma and Improve Quality of Life Among People With Mental Illness in Chile | March 2014 | March 2016 |
| NCT00546403 | Completed | N/A | Modafinil Augmentation Therapy for Excessive Daytime Sleepiness and Negative Symptoms in Patients With Schizophrenia | February 2003 | February 2008 |
| NCT01028196 | Completed | Observational Study to Evaluate Bipolar Disorder Symptoms in Patients Presented With Schizophrenia or Depression | November 2009 | November 2010 | |
| NCT05463770 | Completed | Phase 1 | A Clinical Study That Will Assess the Effect of SEP-363856 and Prior Antipsychotic (PA) Standard of Care on Glucose and Regulation of Insulin in Patients With Schizophrenia | August 30, 2022 | August 22, 2023 |
| NCT03130478 | Completed | Predictors of Persistence in Patients With Schizophrenia Treated With Once-monthly Aripiprazole in Spain | July 18, 2017 | July 30, 2018 | |
| NCT01368406 | Completed | N/A | Lifestyle Intervention for Weight Gain Management for Patients With Schizophrenia | August 2007 | March 2009 |
| NCT01036282 | Completed | Phase 4 | Cognitive Skills Training Using Computer for Patients With Severe Mental Illness | February 2003 | December 2016 |
| NCT03114488 | Completed | N/A | Modulating Human Cortical Plasticity With Transcranial Electrical Stimulation | December 1, 2017 | October 5, 2018 |
| NCT00392197 | Completed | Phase 4 | Study of Aripiprazole in Patients With Schizophrenia- Effects on Glucose Metabolism- | November 2006 | March 2010 |
| NCT00588731 | Completed | Phase 2 | Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia | February 2009 | December 2013 |
| NCT01235520 | Completed | Phase 3 | A Study of RO4917838 in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (NN25307) | January 2011 | July 2014 |
| NCT01620060 | Completed | Phase 1 | Lurasidone Pediatric Pharmacokinetics Study | June 2012 | May 2013 |
| NCT02676375 | Completed | Phase 4 | Nicotine Receptor Density & Response to Nicotine Patch: Pt 2 Extended Treatment | January 2014 | June 2016 |
| NCT02687984 | Completed | Phase 1 | PK, Safety, and Tolerability Study of RBP-7000 of Different Molecular Weight Polymer in Subjects With Schizophrenia | February 2016 | May 2016 |
| NCT00113594 | Completed | Phase 3 | Olanzapine Treated Adolescents With Schizophrenia or Bipolar I Disorder | June 2005 | March 2006 |
| NCT00366171 | Completed | Phase 3 | Open Label Extension Study of Bifeprunox | November 2006 | October 2007 |
| NCT03537703 | Completed | N/A | Transcranial Direct Current Stimulation and Effects on Early Auditory Processing in Schizophrenia | May 20, 2018 | May 1, 2020 |
| NCT00269919 | Completed | Phase 4 | An Efficacy and Safety Study of Long-Term Risperidone Microspheres in Participants With Schizophrenia | August 2005 | August 2008 |
| NCT02748486 | Completed | N/A | Efficacy of Metacognitive Training Single Modules: Jumping to Conclusions and To Empathize... | May 2014 | August 2015 |
| NCT00320697 | Completed | Phase 4 | Smoking Relapse Prevention in Schizophrenia | April 2006 | August 2009 |
| NCT02435784 | Completed | N/A | The Two-Way Communication Checklist (2-COM) in First Episode Psychosis Patients in Hong Kong | May 2015 | August 2015 |
| NCT00790777 | Completed | Phase 1 | A Study of the Bioequivalence of 12 mg Paliperidone Extended Release Tablets Manufactured at Gurabo and Vacaville | March 2007 | May 2007 |
| NCT01315509 | Completed | Dental Status of Patients With Severe Mental Illness | April 2011 | September 2012 | |
| NCT02582736 | Completed | Antipsychotics and Risk of Hyperglycemic Emergencies | April 2012 | December 2012 | |
| NCT01001481 | Completed | Schizophrenia Treatment Adherence Investigation (STAI) | July 2007 | September 2009 | |
| NCT00174447 | Completed | Phase 3 | Extension Study of Patients Successfully Treated by Ziprasidone in Study A1281031 | October 2001 | October 2008 |
| NCT00581932 | Completed | Relationship Between Neurotransmitter Receptor Polymorphisms, Plasma Concentrations and Clinical Response to Clozapine | October 2001 | December 2015 | |
| NCT04740944 | Completed | N/A | Salutogenic Approach Based Interview With People With Schizophrenia | December 31, 2018 | December 31, 2019 |
| NCT02075528 | Completed | Phase 4 | Early Prediction of Clinical Response in Patients With Schizophrenia Treated by Paliperidone ER | July 2009 | July 2012 |
| NCT00259870 | Completed | Phase 2 | SB-773812 Administered In Adults With Schizophrenia | September 2005 | August 2007 |
| NCT00000371 | Completed | Phase 3 | Trial of D-Cycloserine in Schizophrenia | August 1996 | April 2002 |
| NCT00177008 | Completed | Phase 4 | Aripiprazole for the Treatment of Schizophrenia With Co-Morbid Social Anxiety | March 2004 | January 2007 |
| NCT00088621 | Completed | Phase 2 | A Study to Test the Safety and Tolerability of a New Medication in the Treatment of Schizophrenia | July 2004 | October 2005 |
| NCT00300404 | Completed | Phase 3 | Effect of Specific Anti-Toxoplasmatic Add-on Medication in Toxoplasma Gondii Seropositive Individuals With Schizophrenia or Major Depression | January 2002 | September 2005 |
| NCT02505477 | Completed | Phase 4 | Treatment of Cognitive and Negative Symptoms in Schizophrenia With N-acetylcysteine | February 6, 2017 | January 31, 2023 |
| NCT01423916 | Completed | Phase 1 | Trial to Evaluate the Effects of OPC-34712 on QT/QTc in Subjects With Schizophrenia or Schizoaffective Disorder | July 2011 | March 2012 |
| NCT02983188 | Completed | Phase 2/Phase 3 | Berberine as Adjuvant Treatment for Schizophrenia Patients | April 25, 2018 | January 4, 2021 |
| NCT00750087 | Completed | Non-interventional Study -Observe Treatment Efficacy in Maintaining Symptoms Control in Schizophrenia With Seroquel XR | August 2008 | September 2009 | |
| NCT00283179 | Completed | Phase 3 | Aripiprazole in the Treatment of Acutely Relapsed Patients With Schizophrenia | March 2004 | December 2004 |
| NCT02664129 | Completed | N/A | Video as a Tool to Improve Insight in Schizophrenia | December 8, 2015 | December 30, 2018 |
| NCT01234454 | Completed | N/A | Atypical Antipsychotic Treatment Effect On Brain Function In Schizophrenia Measured By FMRI | January 2002 | December 2007 |
| NCT01123408 | Completed | N/A | Clozapine and Olanzapine Treatment of Aggression | June 1999 | July 2004 |
| NCT01041274 | Completed | Phase 4 | DECIFER: Depression and Citalopram In First Episode Recovery | January 2010 | March 26, 2018 |
| NCT00848432 | Completed | Phase 4 | Risperidone Maintenance Treatment in Schizophrenia | December 2002 | December 2004 |
| NCT01098110 | Completed | Phase 3 | 6-week Trial of the Efficacy and Safety of Asenapine Compared to Placebo in Participants With an Acute Exacerbation of Schizophrenia (P06124) | May 25, 2010 | April 14, 2014 |
| NCT00351936 | Completed | Phase 4 | A Placebo-Controlled, Cross-Over Trial of Aripiprazole | December 2005 | July 2007 |
| NCT00463346 | Completed | Phase 3 | Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism | September 2006 | July 2015 |
| NCT00524979 | Completed | Digital Voice Analysis in Patients With Schizophrenia | October 2007 | November 2007 | |
| NCT01101464 | Completed | Phase 2 | A Trial to Determine Whether Two Differing Strength Tablets (3 x 5 mg Versus 1 x 15 mg) of Sublingually Org 5222 (Asenapine) Are Safe and Equal in Subjects With Schizophrenia or Schizoaffective Disorder (P05937) | October 2002 | December 2002 |
| NCT00864825 | Completed | Phase 4 | Allopurinol in Schizophrenia: A Randomized Trial Administering Allopurinol vs Placebo as add-on Antipsychotics in Patients With Schizophrenia | August 2009 | January 2010 |
| NCT00654576 | Completed | Phase 4 | Effectiveness of Antipsychotic Combination With Psychosocial Intervention on Outcome of Patients With Schizophrenia | February 2005 | December 2007 |
| NCT01487668 | Completed | N/A | Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders | December 2011 | May 2015 |
| NCT00220870 | Completed | N/A | Shared Decision Making for Schizophrenia | January 2003 | August 2005 |
| NCT00815854 | Completed | N/A | Examining Risk Factors for Atypical Antipsychotic Metabolic Side Effects | October 2008 | May 2019 |
| NCT00216476 | Completed | Phase 3 | A Study of Relapse Prevention and the Effectiveness of Long-acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder | October 2004 | November 2007 |
| NCT00309413 | Completed | Phase 2 | A Clinical Trial on the Antipsychotic Properties of Cannabidiol | March 2006 | July 2008 |
| NCT02469389 | Completed | N/A | Improving Negative Symptoms & Community Engagement in Veterans With Schizophrenia | August 3, 2015 | May 27, 2020 |
| NCT00139906 | Completed | Phase 2 | Twice Daily Titration Study of Bifeprunox in Subjects With Schizophrenia | August 2005 | October 2006 |
| NCT01150448 | Completed | Phase 1 | A Safety and Pharmacokinetic Study of Paliperidone Palmitate in Patients With Schizophrenia | September 2007 | June 2009 |
| NCT04767204 | Completed | N/A | The Outcomes Among Persons With Schizophrenia Under the Peer-support Service in Vocational Rehabilitation Program | April 1, 2017 | December 30, 2019 |
| NCT03055520 | Completed | N/A | Arithmetic Training With the Kumon Method for Cognition in Schizophrenia | June 2009 | June 2011 |
| NCT00770237 | Completed | N/A | Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Smokers With and Without Schizophrenia | October 2008 | December 2010 |
| NCT01655680 | Completed | Phase 2 | A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia | May 2012 | July 2014 |
| NCT01876524 | Completed | N/A | tRNS in Anterior Cingulate Cortex Reduces Craving Over Dual Pathology Patients | July 2013 | September 2014 |
| NCT01788436 | Completed | Early Phase 1 | A Study to Assess Learning Performance in Patients With Schizophrenia and Young and Elderly Healthy Volunteers | November 2012 | May 2014 |
| NCT00716755 | Completed | N/A | Minimizing Doses of Antipsychotic Medication in Older Patients With Schizophrenia. | October 2009 | August 2015 |
| NCT04629898 | Completed | N/A | Level of Immersion of Virtual Reality and Cognition and Motor Performance in Patients of Schizophrenia Spectrum Disorder | August 1, 2017 | July 31, 2018 |
| NCT02634671 | Completed | N/A | Perception of Facial Emotions in Schizophrenia and 22q11 Deletion Syndrome | November 2015 | December 30, 2017 |
| NCT05090644 | Completed | Program for the Introduction Into Clinical Practice of the Principles of Personalized and Preventive Medicine Based on the Isolation of Gene Polymorphism in Schizophrenia in People of the Kazakh Ethnic Group | March 30, 2022 | January 20, 2023 | |
| NCT02756065 | Completed | Connectomics in Psychiatric Classification of Bipolar Disorder and Schizophrenia | September 2014 | August 2019 | |
| NCT02782442 | Completed | N/A | Cognitive Training Delivered Remotely to Individuals With Psychosis (ROAM) | September 1, 2016 | March 12, 2022 |
| NCT02302209 | Completed | Phase 1 | Dyad Oxytocin Study (DOS) | April 2011 | October 2017 |
| NCT02398292 | Completed | N/A | A Multi-modal Approach to Addressing Cardiovascular Risk and Building Resilience in Youths With Psychosis | February 2015 | July 2016 |
| NCT01566162 | Completed | Phase 3 | A Twelve Week, Open Label Extension Study in Patients With Schizophrenia | April 2012 | November 2013 |
| NCT00832845 | Completed | N/A | Cognitive Behavioral Social Skills Training for Patients With Late-Life Schizophrenia: a Pilot Study | June 2008 | May 2014 |
| NCT01511406 | Completed | Phase 2 | Cognitive Behavioral Therapy for Patients With an Early Psychosis | January 2011 | October 2014 |
| NCT01138618 | Completed | Hematological Clozapine Monitoring With a Point-of-care Device (CHEMPAQ) | April 2010 | May 2011 | |
| NCT01773239 | Completed | N/A | Randomized Clinical Trial of Intensive Computer-based Cognitive Remediation in Recent-onset Schizophrenia | May 2012 | July 2013 |
| NCT01552772 | Completed | Phase 1 | Safety and Tolerability Trial of Aripiprazole IM Depot Treatment in Adult Subjects With Schizophrenia Stabilized on Oral Antipsychotics Other Than Aripiprazole | January 2012 | April 2012 |
| NCT01182727 | Completed | N/A | Salsalate for Insulin Resistance in Schizophrenia | August 2010 | December 2011 |
| NCT00207064 | Completed | N/A | Neurobiological and Neurocognitive Disturbances in First-episode Schizophrenia | April 2004 | September 2008 |
| NCT00358709 | Completed | Phase 3 | Treating Psychotic Symptoms of Young Individuals Presenting a First Episode of Schizophrenia: Comparison of Two State-of-the-Art Interventions | June 2002 | December 2006 |
| NCT00001192 | Completed | Neuropsychological Evaluation of Psychiatric and Neurological Patients | October 18, 1983 | December 20, 2006 | |
| NCT01047592 | Completed | Phase 2 | Treatment of N-methyl-D-aspartate (NMDA) Enhancers for Schizophrenia | March 2009 | December 2013 |
| NCT02765555 | Completed | Phase 1 | First in Man Study of Safety, Tolerability and PK Profile of RBP-7000 | March 2010 | September 2010 |
| NCT00924976 | Completed | N/A | Improving Representative Payeeship for People With Psychiatric Disabilities and Their Families | May 2008 | April 2011 |
| NCT00202306 | Completed | Phase 4 | Indicated Prevention of Psychotic Disorders With Low-dose Lithium | November 2001 | December 2006 |
| NCT00836251 | Completed | Effects of Antipsychotic Medications on Energy Intake and Expenditure | April 2006 | June 2008 | |
| NCT03558529 | Completed | Feasibility and Acceptability of a Smartphone App to Assess Early Warning Signs of Psychosis Relapse | May 1, 2015 | April 1, 2018 | |
| NCT00696813 | Completed | Observational Study to Assess Outcomes During Antipsychotic Treatment With Paliperidone ER or Other Oral Antipsychotics | June 2008 | January 2011 | |
| NCT03382639 | Completed | Phase 2 | A Study to Evaluate 3 Dose Levels of Luvadaxistat of Adults With Negative Symptoms of Schizophrenia | January 4, 2018 | January 12, 2021 |
| NCT00071591 | Completed | Phase 2 | Rehabilitative Training for Older People With Schizophrenia | July 2001 | November 2006 |
| NCT04787302 | Completed | Phase 1 | PET Trial to Evaluate Target Occupancy of CVL-231 on Brain Receptors Following Oral Dosing | June 1, 2021 | July 14, 2023 |
| NCT01046526 | Completed | fMRI Study of Nicotinic Effect on Neurophysiology of Schizophrenia | February 8, 2005 | May 3, 2012 | |
| NCT00859872 | Completed | Phase 4 | Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol Intramuscular (IM) Injection for Treatment of Acute Psychotic Agitation in Schizophrenia | August 2008 | March 2009 |
| NCT01698216 | Completed | Switching From Consta® to Sustenna® in Patients With Schizophrenia | December 2011 | May 2015 | |
| NCT02593058 | Completed | N/A | Positive Emotions Program for Schizophrenia (PEPS) | February 1, 2016 | December 31, 2018 |
| NCT00585273 | Completed | Antipsychotics and Blood Vessel Function | September 2007 | December 2014 | |
| NCT02069392 | Completed | N/A | Nicotinic Enhancement of Cognitive Remediation Training in Schizophrenia | January 2015 | June 2017 |
| NCT01324973 | Completed | N/A | Web-Based Weight Management for Individuals With Mental Illness | March 2012 | April 2014 |
| NCT00239356 | Completed | Phase 3 | Aripiprazole for Schizophrenia Outpatients Completing BMS Clinical Trials | March 2003 | October 2012 |
| NCT03408327 | Completed | N/A | The Application of Wearable Technology to Improve the Physical Activity Level of People With Chronic Mental Illness | March 16, 2018 | July 31, 2020 |
| NCT01266174 | Completed | Phase 2 | Effects of Eltoprazine on Cognitive Impairment Associated With Schizophrenia (CIAS) in Adults | August 2011 | November 2012 |
| NCT00161057 | Completed | Functional Brain Activation Patterns in Schizophrenia, Measured Before and After Treatment | December 2001 | September 2008 | |
| NCT00712660 | Completed | N/A | Study With Information Technology (IT) - Aided Preventive Program in Schizophrenia | November 2008 | March 2012 |
| NCT00328367 | Completed | Phase 4 | Aripiprazole Augmentation for Clozapine-Treated Patients With Refractory Schizophrenia | December 2005 | February 2008 |
| NCT05111548 | Completed | N/A | Brain Stimulation and Cognitive Training - Efficacy | September 8, 2021 | May 12, 2023 |
| NCT03528278 | Completed | Using Motivational Techniques to Increase Levels of Physical Activity in Long Term Psychiatric Inpatient Wards | January 23, 2013 | March 10, 2015 | |
| NCT00511277 | Completed | Phase 4 | Efficacy and Safety of Quetiapine in Treating Affective Symptoms of Patients With First-episode psychosis-a Pilot Study | August 2007 | April 2011 |
| NCT00324051 | Completed | Phase 4 | Patient's Preference Between Conventional Oral Olanzapine Tablet vs Olanzapine Orodispersible Tablet | May 2006 | September 2007 |
| NCT02418819 | Completed | Phase 1 | A Study To Examine Safety, Pharmacokinetics, And Pharmacodynamic Of Pf 06412562 In Subjects With Schizophrenia | April 2015 | October 2016 |
| NCT00108303 | Completed | Genetic Research in Schizophrenia Using DNA Markers and Clinical Phenotypes | January 2004 | December 2008 | |
| NCT00100776 | Completed | Phase 4 | Efficacy of High Dose Olanzapine for the Treatment of Schizophrenia and Schizoaffective Disorder | September 2003 | November 2005 |
| NCT00395031 | Completed | Phase 2/Phase 3 | Effect of Ziprasidone on Glucose & Plasma Lipids in Diabetes (II) and Schizophrenia or Schizoaffective Disorder | September 2003 | January 2010 |
| NCT03068806 | Completed | Brain Imaging, Attention, and Auditory Processing in Schizophrenia | December 1, 2014 | May 11, 2018 | |
| NCT01192880 | Completed | Phase 3 | A Study to Evaluate Efficacy and Safety of Bitopertin in Participants With Persistent, Predominant Negative Symptoms of Schizophrenia | November 2010 | July 2014 |
| NCT00291200 | Completed | Enhancing the Prospective Prediction of Psychosis | August 2003 | February 2009 | |
| NCT00420498 | Completed | Phase 2 | Effects of Atomoxetine on Cognitive Function in Schizophrenia | August 2005 | September 2007 |
| NCT01139099 | Completed | N/A | The Evaluation of Therapeutic Efficacy on the Integrated Group Psychotherapy for Patients With Schizophrenia | May 2010 | May 2011 |
| NCT02174510 | Completed | Phase 1 | A Pharmacokinetic Study of Lurasidone After Single Oral Administration in Healthy Subjects | March 2014 | April 2014 |
| NCT00560937 | Completed | N/A | Pilot Study of Pregnenolone Augmentation Targeting Cognitive Symptoms in Persistently Symptomatic Patients With Schizophrenia | June 2005 | April 2008 |
| NCT00230828 | Completed | Phase 3 | Patient-reported Outcomes in the Treatment of Schizophrenia | May 2005 | |
| NCT04709224 | Completed | Phase 1 | Pharmacokinetics, Safety, and Tolerability of Lumateperone Long-Acting Injectable in Patients With Schizophrenia | December 30, 2020 | May 23, 2022 |
| NCT00097942 | Completed | Phase 2 | Evaluation of the Safety and Efficacy of Memantine as Adjunctive Treatment in Schizophrenia Patients | August 2004 | September 2005 |
| NCT00001921 | Completed | Electrophysiology and Blood Flow in Patients With Schizophrenia and Their Siblings | September 21, 1999 | June 8, 2018 | |
| NCT00543088 | Completed | Effectiveness of Anti-Psychotic in GPs Setting | January 2007 | June 2008 | |
| NCT01258920 | Completed | Phase 3 | A Study of Paliperidone Palmitate in Japanese Patients With Schizophrenia | October 2010 | November 2012 |
| NCT03129360 | Completed | Phase 2 | Levetiracetam in Early Psychosis | August 18, 2017 | November 3, 2021 |
| NCT02237417 | Completed | Phase 4 | Study of the Impact of Aripiprazole (Abilify®) Once Monthly Versus Standard of Care Oral Antipsychotic Medications on Changes in Brain Structure and Metabolism | September 1, 2014 | July 30, 2020 |
| NCT01154829 | Completed | N/A | Pan European Collaboration on Antipsychotic Naive Schizophrenia (PECANS) | December 2008 | May 2016 |
| NCT00139737 | Completed | Phase 3 | Extension Study: Evaluating the Safety of Oral Ziprasidone in the Treatment of Subjects With Schizophrenia | March 2002 | June 2009 |
| NCT00167817 | Completed | Phase 4 | Effect of Switch to Aripiprazole on Health and Smoking Parameters in Patients With Schizophrenia: A Pilot Study | July 2003 | September 2005 |
| NCT02246426 | Completed | N/A | Treatment of Social Cognition in Schizophrenia Trial | March 2015 | August 30, 2018 |
| NCT01206842 | Completed | N/A | Social Cognition Training in Schizophrenia | August 2011 | May 1, 2018 |
| NCT01611337 | Completed | N/A | Insight in Persons Presenting Schizophrenia or Related Troubles During Hospitalization in Psychiatry | June 2012 | July 2017 |
| NCT00845572 | Completed | N/A | The Consta Club: A Demonstration Project for Setting up a Consta Club in a Community Mental Health Center | January 2007 | June 2010 |
| NCT00817648 | Completed | Phase 4 | A Study to Evaluate the Efficacy and Safety of Seroquel in Chinese Han Patients With Schizophrenia | December 2008 | May 2010 |
| NCT00435370 | Completed | Phase 3 | Effectiveness of Tropisetron Plus Risperidone for Improving Cognitive and Perceptual Disturbances in Schizophrenia | November 2006 | August 2011 |
| NCT03446703 | Completed | N/A | SCIT Versus TAR for Outpatients With Schizophrenia | September 1, 2013 | June 30, 2017 |
| NCT01111149 | Completed | Phase 2 | Varenicline and Smoking Cessation in Schizophrenia | December 2009 | August 2012 |
| NCT00505765 | Completed | Phase 2 | A Multicenter Study of NAP (AL-108) in Schizophrenia | July 2007 | April 2009 |
| NCT00155506 | Completed | Molecular Genetic Study of Schizophrenia: Parent-Offspring Trios | November 2002 | December 2004 | |
| NCT00088478 | Completed | Phase 3 | Comparison of Intramuscular Olanzapine Depot With Placebo in the Treatment of Patients With Schizophrenia | June 2004 | April 2005 |
| NCT00102518 | Completed | Phase 3 | Aripiprazole Open-Label, Safety and Tolerability Study | September 2004 | February 2007 |
| NCT00044005 | Completed | Phase 2 | Safety and Tolerability Study of Drug to Treat Schizophrenia | September 2002 | November 2003 |
| NCT00174265 | Completed | Phase 3 | 6-Month Extension Trial of Asenapine With Olanzapine in Negative Symptoms Patients Who Completed the First 6- Month Trial (A7501014)(COMPLETED)(P05772) | July 2005 | May 2009 |
| NCT01952132 | Completed | Phase 2 | Safety, Tolerability, and Pharmacokinetics of OMS643762 in Psychiatrically Stable Schizophrenia Subjects | September 2013 | April 2014 |
| NCT01568528 | Completed | Phase 2 | Oxytocin as Adjunctive Treatment of Schizophrenia | March 2013 | March 15, 2017 |
| NCT02160249 | Completed | N/A | RISE (Rehabilitation Intervention for People With Schizophrenia in Ethiopia) | September 2015 | May 8, 2017 |
| NCT00579670 | Completed | Treatment of Schizophrenic Patients With Ziprasidone | October 2007 | April 2009 | |
| NCT02930083 | Completed | Validating Three Common Occupational Therapy Assessments in Participants With Schizophrenia | October 2012 | December 2015 | |
| NCT01596608 | Completed | N/A | Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive Disorder | February 2012 | June 2019 |
| NCT00694889 | Completed | Phase 1/Phase 2 | Randomized Clinical Trial of Intensive Computer-based Cognitive Remediation in Recent-onset Schizophrenia | August 2007 | February 2015 |
| NCT02804568 | Completed | Phase 1 | A Phase 1 Safety Study in Adults With Schizophrenia | June 2016 | August 2016 |
| NCT00644852 | Completed | Medical Chart Review of Patients on Long-term Treatment With Long-acting Injectable Risperidone | January 2007 | September 2007 | |
| NCT03995368 | Completed | N/A | Neuroplasticity in TBI and Schizophrenia | November 9, 2020 | April 19, 2023 |
| NCT02532686 | Completed | Phase 2 | DAAOI-2 add-on Treatment for Treatment-resistant Schizophrenia | October 2014 | July 2016 |
| NCT04106427 | Completed | N/A | Brain Stimulation And Group Therapy to Improve Gesture and Social Skills in Psychosis (BrAGG-SoS) | December 1, 2019 | April 24, 2024 |
| NCT04134871 | Completed | N/A | Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People With SMI | August 22, 2019 | December 31, 2022 |
| NCT01541371 | Completed | Phase 3 | A Study of Flexibly Dosed Paliperidone Extended Release Tablets in Participants With Schizophrenia | July 2008 | September 2009 |
| NCT01926340 | Completed | Early Medication Discontinuation and Long-term Clinical Outcome in FEP | November 2013 | March 2015 | |
| NCT00759421 | Completed | Phase 3 | Exploratory Cognition Study of Sertindole in Patients With Schizophrenia | October 2006 | April 2008 |
| NCT02034253 | Completed | Glutamate, Brain Connectivity and Duration of Untreated Psychosis | January 2014 | November 2018 | |
| NCT00894842 | Completed | Phase 2/Phase 3 | Study of a Neurocognition Enhancing Agent in Patients With Schizophrenia | June 2009 | September 2011 |
| NCT05207319 | Completed | N/A | Effects of Integrated Moral Reasoning Development Intervention for Management of Violence in Schizophrenia | September 1, 2019 | December 31, 2020 |
| NCT00486005 | Completed | Phase 4 | Weight Gain Management in Patients With Schizophrenia | February 2003 | October 2003 |
| NCT01879709 | Completed | N/A | Yoga as Cognitive Remediation in Schizophrenia | August 2010 | July 2016 |
| NCT02281773 | Completed | Phase 2 | A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks in Patients With Schizophrenia on Stable Antipsychotic Treatment. | November 10, 2014 | June 13, 2016 |
| NCT01091506 | Completed | N/A | A Placebo-Controlled Study of Physiologic Effects of L-methylfolate in Schizophrenia Patients | March 2010 | June 2014 |
| NCT03565068 | Completed | Phase 1 | A Safety, Tolerability, and Pharmacokinetics Study of MK-8189 in Participants With Schizophrenia and in Healthy Participants (MK-8189-007) | June 20, 2018 | April 3, 2020 |
| NCT00182442 | Completed | Phase 4 | Cognition, Functioning and Quality of Life | October 2003 | March 2006 |
| NCT03465787 | Completed | Phase 3 | A 6-week Study to Evaluate the Efficacy and Safety of Lurasidone HCL in Acutely Psychotic Patients With Schizophrenia | April 9, 2018 | October 26, 2022 |
| NCT02658357 | Completed | Phase 2 | Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)-Risperidone When Risperidone is Administered From a Polyurethane Implant | October 2015 | August 2017 |
| NCT00205725 | Completed | N/A | Pfizer/IVGTT/Ziprasidone/Olanzapine | November 2000 | October 2006 |
| NCT01940159 | Completed | Phase 1 | A Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects With Schizophrenia | August 2013 | March 2014 |
| NCT02768649 | Completed | Phase 1 | Single Ascending Dose Study of RBP-7000 | April 2011 | February 2012 |
| NCT02074319 | Completed | Phase 1 | RCT of Methotrexate Added to Treatment As Usual in Schizophrenia | December 2013 | August 2015 |
| NCT00205608 | Completed | Phase 1 | Microglia Activation in Schizophrenia | January 2004 | December 2007 |
| NCT01620086 | Completed | N/A | Effect of Repetitive Transcranial Magnetic Stimulation on Resting State Brain Activity in Schizophrenia | June 2012 | August 2015 |
| NCT00817154 | Completed | Phase 1 | Individually Based Psychosocial Rehabilitation for Older People With Serious Mental Illness (SMI) | November 2009 | December 2013 |
| NCT04350775 | Completed | N/A | Investigation of Community Reablement on Instrumental Activities of Daily Living in People With Schizophrenia | November 30, 2021 | July 6, 2022 |
| NCT00237913 | Completed | Phase 3 | Schizophrenia Trial of Aripiprazole | July 2004 | August 2005 |
| NCT01235559 | Completed | Phase 3 | A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25305) | December 2010 | March 2015 |
| NCT04068467 | Completed | N/A | Evaluation of mHealth for Serious Mental Illness | January 6, 2020 | May 1, 2021 |
| NCT00847600 | Completed | Phase 4 | Pregnenolone Augmentation in the Treatment of Patients With Recent-Onset Schizophrenia | March 2009 | December 2010 |
| NCT00378092 | Completed | Phase 4 | A Follow-Up Study of Schizophrenic Participants Following Treatment Discontinuation After Remission From a First Psychotic Episode | April 2006 | March 2010 |
| NCT00862992 | Completed | Phase 2 | Safety, Pharmacokinetics and Efficacy Study of MP-214 in Patients With Schizophrenia | April 2008 | September 2009 |
| NCT01897064 | Completed | N/A | The Influence of Aerobic Exercise on Cognitive Functioning in Schizophrenia. | April 2012 | July 2014 |
| NCT02773576 | Completed | Phase 3 | Safety and Tolerability of Risperidone Implants | April 2016 | September 2017 |
| NCT02124811 | Completed | Phase 4 | Minocycline Augmentation to Clozapine | February 2015 | November 2016 |
| NCT01104766 | Completed | Phase 3 | Safety and Efficacy of Cariprazine in Patients With Schizophrenia | April 23, 2010 | December 20, 2011 |
| NCT01060228 | Completed | Phase 1 | A Drug Interaction Study of Valproic Acid and Single-dose Paliperidone Extended-Release (ER) in Healthy Men | January 2009 | February 2009 |
| NCT02254733 | Completed | N/A | Assertive Community Treatment With CBT and SST for Schizophrenia | February 2012 | August 2016 |
| NCT00034905 | Completed | Phase 4 | A Comparison of Seroquel vs. Risperidone in Schizophrenia | July 2001 | September 2002 |
| NCT02782091 | Completed | N/A | Discriminant Validity of the Multiple Errands Test in Schizophrenia | June 16, 2016 | January 21, 2020 |
| NCT02248987 | Completed | Study on Abnormal Dopamine Synthesis and Connectivity According to the Antipsychotic Treatment Response in Schizophrenia | May 2014 | May 2016 | |
| NCT01617200 | Completed | Phase 3 | Long-Term Safety Extension Trial of Asenapine in Schizophrenia Participants Who Completed Protocol P05688 (P05689) | December 2012 | March 2015 |
| NCT01246232 | Completed | Phase 4 | Amisulpride Augmentation in Clozapine-unresponsive Schizophrenia | September 2011 | March 2015 |
| NCT02086786 | Completed | Phase 2 | Pharmacokinetics and Tolerability Study of Risperidone ISM® in Schizophrenia | March 2014 | March 2015 |
| NCT00206102 | Completed | Phase 4 | A Study of the Cataractogenic Potential of Seroquel and Risperdal in the Treatment of Participants With Schizophrenia or Schizoaffective Disorder | September 2003 | October 2008 |
| NCT00375050 | Completed | N/A | Treatment of Refractory Schizophrenia With Riluzole | May 2002 | August 29, 2006 |
| NCT00611806 | Completed | Phase 4 | Effectiveness of Vitamin Supplementation in Treating People With Residual Symptoms of Schizophrenia | December 2007 | December 2010 |
| NCT03404882 | Completed | N/A | Peer Support Experience for Patients Discharged From Acute Psychiatric Care | June 1, 2019 | November 1, 2020 |
| NCT00761670 | Completed | Phase 4 | Efficacy Study on Cognitive Functions in Schizophrenic Patients | September 2008 | January 2010 |
| NCT01207414 | Completed | Phase 4 | Switching to Iloperidone From Other Antipsychotics in Schizophrenia | August 2010 | January 2012 |
| NCT03179696 | Completed | N/A | Mobile-Assisted Cognitive Behavior Therapy for Negative Symptoms in Schizophrenia | August 15, 2016 | October 31, 2018 |
| NCT00501163 | Completed | Direct Measurements of Cardiometabolic Risk in Treated Schizophrenia Patients | August 2007 | May 2012 | |
| NCT01947803 | Completed | Phase 4 | A Safety and Effectiveness Study of Paliperidone Palmitate in Chinese Patients With Schizophrenia | September 2013 | March 2015 |
| NCT00141479 | Completed | Phase 2 | To Evaluate the Impact of Treatment Interruption on Re-initiation of Bifeprunox | May 2005 | November 2006 |
| NCT06356389 | Completed | Phase 1/Phase 2 | A Clinical Trial to Evaluate Safety, Tolerance and Pharmacokinetics of JX11502MA Capsule in Patients With Schizophrenia. | March 2, 2022 | January 28, 2023 |
| NCT01348100 | Completed | Phase 1/Phase 2 | Safety, Tolerability, and Pharmacokinetics of Iloperidone Depot in Schizophrenic Patients | April 2011 | July 2012 |
| NCT03379480 | Completed | N/A | Study on Examination of Therapeutic Efficacy and Potential Mechanisms of Yoga Treatment in Schizophrenia | November 11, 2016 | June 2020 |
| NCT00272168 | Completed | N/A | The Use of Skills Training to Augment Compensated Work Therapy (CWT)/VI for Veterans With SMI | October 2005 | October 2009 |
| NCT02062190 | Completed | Phase 2 | Resveratrol, Cardiovascular Risk Markers And Cognitive Performance In Patients With Schizophrenia | March 2014 | May 2015 |
| NCT02164981 | Completed | Phase 2 | A Proof of Concept Study of Intravenous Sodium Nitroprusside in Adults With Symptomatic Schizophrenia | May 1, 2015 | April 5, 2017 |
| NCT00156117 | Completed | Phase 3 | Efficacy and Safety of Asenapine With Placebo and Olanzapine (41021)(P05933) | May 12, 2005 | May 30, 2006 |
| NCT03251716 | Completed | N/A | Berberine Treat Metabolic Syndrome in Schizophrenia | January 1, 2015 | December 30, 2017 |
| NCT00246285 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Risperidone in the Treatment of Adolescents With Schizophrenia | April 2001 | December 2006 |
| NCT05345977 | Completed | N/A | eMotiph: E-mental Health Solution for Patients With Schizophrenia | June 1, 2021 | February 28, 2022 |
| NCT00757978 | Completed | Phase 4 | Memantine as Adjunctive Therapy for Schizophrenia Negative Symptoms | January 2006 | March 2008 |
| NCT01779700 | Completed | Phase 2 | Fingolimod in Schizophrenia Patients | January 2013 | August 2016 |
| NCT02104752 | Completed | Phase 1/Phase 2 | Curcumin as a Novel Treatment to Improve Cognitive Dysfunction in Schizophrenia | July 2014 | October 2017 |
| NCT02146547 | Completed | Phase 4 | European Long-acting Antipsychotics in Schizophrenia Trial | February 2015 | August 26, 2020 |
| NCT00265551 | Completed | Phase 2 | Study Evaluating SCA-136 in Subjects With Acute Exacerbations of Schizophrenia | January 2006 | January 2007 |
| NCT00796029 | Completed | Phase 1 | A Study of Plasma Concentrations, Metabolism and Excretion of 14C-paliperidone After a Single Oral Dose | July 2003 | July 2003 |
| NCT03037983 | Completed | N/A | Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation | August 1, 2017 | July 18, 2019 |
| NCT01299454 | Completed | Phase 1 | A Study Evaluating the of OPC-34712 in Subjects With Normal Hepatic Function and Hepatically Impaired Subjects | December 2010 | July 2011 |
| NCT00236587 | Completed | Phase 3 | A Long Term Study of Long-acting Injectable Risperidone in the Treatment of Patients With Schizophrenia | November 2001 | February 2004 |
| NCT00731549 | Completed | Phase 3 | Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia | December 2008 | November 2013 |
| NCT00611741 | Completed | Phase 1 | The Effect of Plasma Osmolality on Brain Glutamate | March 2007 | March 2012 |
| NCT00514423 | Completed | N/A | How Can Rehospitalisations of Patients With Schizophrenia be Avoided? A Comparison Between Different Compliance Programs | September 2006 | December 2011 |
| NCT01614899 | Completed | Phase 3 | A Phase III Study of SM-13496 (Lurasidone HCl) in Patients With Schizophrenia | July 2, 2012 | November 17, 2014 |
| NCT03451734 | Completed | Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients | January 23, 2018 | June 30, 2021 | |
| NCT01972711 | Completed | Phase 1 | Study Assessing SEP-363856 in Male and Female Volunteers With High or Low Schizotype Characteristics | March 2014 | July 2015 |
| NCT02007928 | Completed | N/A | Assessment of Adverse Events in a Naive Pediatric Population Treated With an Antipsychotic | April 2013 | July 2017 |
| NCT01512641 | Completed | N/A | Prevalence of Dissociative Disorders in Children | December 2011 | May 2013 |
| NCT02935725 | Completed | Phase 1 | A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males | October 2016 | November 2017 |
| NCT02667834 | Completed | N/A | Efficiency of the French Translation Social Cognition and Interactive Training (SCIT)Program | October 2014 | October 2019 |
| NCT01010776 | Completed | Phase 4 | A Study to Evaluate Participants Satisfaction, Quality of Life and Effectiveness of Flexible-Dose of Paliperidone Extended Release (ER) in Participants With Schizophrenia, Previously Treated With Risperidone | February 2008 | December 2009 |
| NCT00166322 | Completed | N/A | Dopaminergic Neurotransmission in Schizophrenia, Patients at Risk and Healthy Subjects | January 2004 | December 2007 |
| NCT00713804 | Completed | Phase 3 | Impact of Genetic Counseling for Individuals With Mental Illness | July 2008 | November 2011 |
| NCT03978832 | Completed | Phase 4 | Safety, Tolerability, Pharmacokinetics and Efficacy of 180 mg Subcutaneous Risperidone From 6 mg Oral Risperidone | June 28, 2019 | May 12, 2020 |
| NCT00333177 | Completed | Phase 4 | Psychosocial Therapy and Risperidone Treatment in Work Performance in Recent-Onset Schizophrenia | March 2006 | January 2013 |
| NCT01469039 | Completed | Phase 3 | A Study to Evaluate the Efficacy and Safety of ALKS 9072 (Also Known as Aripiprazole Lauroxil, ALKS 9070, or ARISTADA) in Subjects With Schizophrenia | December 2011 | March 2014 |
| NCT05179525 | Completed | Phase 1 | Comparative Bioavailability of Risperidone. | March 9, 2021 | September 17, 2021 |
| NCT00856583 | Completed | Phase 3 | Safety Study of Sertindole Versus Risperidone Under Normal Conditions of Use | July 2002 | February 2008 |
| NCT03822416 | Completed | Phase 2 | Treating Smokers With Mental Illness | March 1, 2019 | May 4, 2020 |
| NCT02625103 | Completed | Phase 4 | The Significance of Deviation in Time From the 12-hour Standard Serum-clozapine Monitoring. | September 2015 | February 2016 |
| NCT00535145 | Completed | Phase 4 | Study to Measure the Safety of Paliperidone ER (Extended-release) in Patients With Liver Disease | October 2007 | February 2009 |
| NCT00246259 | Completed | Phase 4 | A Trial Comparing Risperidone Long-Acting Injection With Oral Antipsychotic in the Treatment of Early Psychosis | October 2004 | December 2008 |
| NCT01523730 | Completed | N/A | Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia | April 2012 | September 2015 |
| NCT00223522 | Completed | Do Self-Report and Physician Impressions of Adherence to Oral Antipsychotic Medication Agree With Objective Data? | April 2004 | March 2005 | |
| NCT00231335 | Completed | Phase 4 | Efficacy and Safety Study of Escitalopram Augmentation in Treatment Resistant Schizophrenia | March 2006 | July 2007 |
| NCT01409590 | Completed | N/A | Exercise and Diet Program for Schizophrenia Patients Who Are Taking Atypical Antipsychotic Medications | May 2005 | August 2009 |
| NCT00722176 | Completed | Phase 2 | Extension Study To Evaluate The Long-Term Safety, Tolerability, And Efficacy Of Low And High Doses Of Bl-1020 | June 2008 | December 2009 |
| NCT01251055 | Completed | Phase 2 | GlyT-1 Inhibitor Treatment for Refractory Schizophrenia | April 2010 | October 2013 |
| NCT00642369 | Completed | N/A | A 4-week, Randomized, Rater-blinded, Parallel Study to Evaluate Quetiapine in Improving Sleep Quality of Schizophrenia | March 2008 | October 2009 |
| NCT02333487 | Completed | Phase 1 | Positron Emission Tomography (PET) Study Investigating Dopamine and Serotonin Receptor Occupancy After Multiple Oral Dosing of Lu AF35700 | December 30, 2014 | February 11, 2016 |
| NCT00640510 | Completed | Phase 3 | A Study Comparing Rapid Acting Intramuscular Olanzapine and Placebo in Agitated Patients With Schizophrenia | March 2008 | July 2008 |
| NCT01142596 | Completed | Phase 3 | Long-term Extension Trial of Asenapine in Subjects With Schizophrenia (Study P06125) | May 25, 2010 | April 22, 2015 |
| NCT02267070 | Completed | N/A | Enhancing Cognitive Training Through Exercise After a First Schizophrenia Episode | November 2013 | July 2017 |
| NCT02187692 | Completed | N/A | The Effectiveness of the Meta-cognitive Training Among Patients With Chronic Schizophrenia | August 2012 | September 2013 |
| NCT02202226 | Completed | Phase 1 | Safety and Tolerability Study of Lu AF35700 After Repeated Dosing in Patients With Schizophrenia | January 2013 | |
| NCT00549718 | Completed | Phase 3 | Lurasidone HCl: A Phase 3 Study of Patients With Acute Schizophrenia | October 2007 | October 2010 |
| NCT00212771 | Completed | Phase 3 | Efficacy and Safety of Asenapine Using an Active Control in Subjects With Schizophrenia or Schizoaffective Disorder (25520)(P05846) | September 2004 | October 2006 |
| NCT02526030 | Completed | Phase 4 | Comparative Study of Aripiprazole, Quetiapine and Ziprasidone in Treatment of First Episode Psychosis: 3-year Follow-up | October 2008 | June 2015 |
| NCT02204787 | Completed | Phase 1/Phase 2 | Treatment of Negative Symptoms and Schizophrenia | April 1, 2014 | October 26, 2018 |
| NCT01662648 | Completed | Phase 3 | Safety, Efficacy and Tolerability Study of Paliperidone Extended-Release (ER) in Participants With Schizophrenia | June 2007 | April 2009 |
| NCT01686815 | Completed | Cross-Sectional Iloperidone IVGTT | October 2012 | May 2016 | |
| NCT01821378 | Completed | Phase 3 | Lurasidone Low-Dose - High-Dose Study Study | May 2013 | June 2014 |
| NCT02970305 | Completed | Phase 2 | Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia (ADVANCE) | November 4, 2016 | October 28, 2019 |
| NCT00761579 | Completed | Phase 4 | Paliperidone Extended Release(ER) Effectiveness Study to Evaluate the Objective Symptom Change and Symptomatic Remission | April 2008 | December 2010 |
| NCT01082588 | Completed | Phase 4 | Effects of Pravastatin on Cholesterol, Inflammation and Cognition in Schizophrenia | June 2010 | September 2012 |
| NCT00601224 | Completed | Phase 1 | Social Cognition and Interaction Training for Improving Social Functioning in People With Schizophrenia | June 2007 | July 2010 |
| NCT00645099 | Completed | Phase 3 | A 6 Month Study to Compare the Metabolic Effects of Paliperidone ER and Olanzapine in Patients With Schizophrenia | October 2007 | April 2009 |
| NCT00018850 | Completed | N/A | 5HT3 Antagonism and Auditory Gating in Schizophrenia | June 1998 | June 2003 |
| NCT00250575 | Completed | Phase 3 | A Study to Evaluate the Safety and Efficacy of Clozapine in Patients With Treatment-resistant Schizophrenia | November 2005 | |
| NCT01185743 | Completed | Phase 4 | Antipsychotics and Gene Expression in Soft Tissues | July 2010 | January 1, 2017 |
| NCT00312598 | Completed | Body Mass Index (BMI) and Metabolic Changes Following Switch to Aripiprazole From Olanzapine, Risperidone and Quetiapine | August 2005 | April 2010 | |
| NCT00796276 | Completed | Phase 1 | A Study of Paliperidone Enantiomer Disposition With Different Formulations and the Bioavailability of Immediate- and Extended-release Paliperidone | May 2004 | August 2004 |
| NCT03714698 | Completed | N/A | Effects of Pilates Exercise Program in Patients With Schizophrenia | October 12, 2016 | July 15, 2018 |
| NCT05130853 | Completed | N/A | Efficacy Study of a New Individualized Rehabilitation Programme for Social Cognition in Patients With Schizophrenia | January 10, 2021 | July 31, 2022 |
| NCT00103727 | Completed | Phase 2 | Study Of Talnetant Versus Placebo And Risperidone In Schizophrenia | December 2004 | October 2005 |
| NCT00580125 | Completed | Phase 2 | Dose-response Study to Evaluate Safety, Efficacy, and Pharmacokinetics of PF-00217830 Compared With Placebo in Acute Exacerbation of Schizophrenia | November 2007 | September 2008 |
| NCT03848234 | Completed | Phase 3 | Estradiol Patch as add-on to Antipsychotics in Patients With Schizophrenia, Schizoaffective or Schizophreniform Disorder | December 4, 2015 | July 29, 2016 |
| NCT01342120 | Completed | PHARMO Institute Seroquel Safety Study | September 2010 | November 2010 | |
| NCT00526877 | Completed | Phase 4 | An Efficacy and Safety Study of Long-acting Risperidone in Participants With Schizophrenia or Schizoaffective Disorders Who Are Receiving Psychiatric Home Care Treatment | July 2007 | January 2009 |
| NCT00369239 | Completed | Phase 4 | Treatment With Risperidone Long Acting Injectable (RLAI) in an Early Phase of Psychosis | March 2006 | November 2007 |
| NCT01232790 | Completed | N/A | A Pilot Trial of Acute N-Acetylcysteine Effects on Working Memory and Other Cognitive Functions in Schizophrenia | February 2010 | November 2011 |
| NCT02304432 | Completed | Early Phase 1 | Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserine | September 27, 2015 | July 31, 2017 |
| NCT00487942 | Completed | Phase 2 | Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive Deficits | July 2007 | December 2007 |
| NCT00210717 | Completed | Phase 3 | A Study to Compare the Effectiveness and Safety of Flexibly Varied Doses of Paliperidone Palmitate and Risperidone in Treating Patients With Schizophrenia | February 2005 | April 2007 |
| NCT00179062 | Completed | N/A | Effects of Risperidone and Olanzapine on Patients With Schizophrenia, Schizoaffective Disorder, Major Depression or Bipolar Disorder | February 2000 | June 2007 |
| NCT05259748 | Completed | N/A | The Effect of Psychoeducation on Healthy Lifestyle Behaviors in Individuals With Schizophrenia | April 1, 2019 | November 2, 2020 |
| NCT00770744 | Completed | Phase 2 | Efficacy of Lu 31-130 in Patients With Schizophrenia | September 2008 | November 2009 |
| NCT02008292 | Completed | N/A | Acetylcholine, Tobacco Smoking, Genes and Nicotinic Receptors | September 2013 | December 2021 |
| NCT01558570 | Completed | Intracellular Tight Junction Permeability in Schizophrenia: Focus on Zonulin | July 2011 | February 2012 | |
| NCT02150174 | Completed | N/A | Testing Effect and Schizophrenia | July 2014 | August 2015 |
| NCT01594528 | Completed | N/A | Behavior During Experimentally Induced Pain | April 2012 | December 2013 |
| NCT02897167 | Completed | Study of the Activation of Proinflammatory Pathways of Toll-like Receptors in Schizophrenia Patients | August 2016 | March 2019 | |
| NCT02477020 | Completed | Phase 2 | A Phase 2 Efficacy and Safety Study of TAK-063 in Participants With an Acute Exacerbation of Schizophrenia | July 1, 2015 | July 27, 2016 |
| NCT00124683 | Completed | Phase 2 | Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1 | September 2001 | May 2007 |
| NCT03376763 | Completed | Phase 4 | MAintain the Efficacy and Safety in Treatment of Schizophrenia After Switching to Long-acTing Injectable aRipiprazole From Oral Atypical Antipsychotics | November 21, 2017 | November 19, 2021 |
| NCT00833456 | Completed | NIS to Observe Improvement in Global Assessment of Functioning in Patients With Schizophrenia | February 2009 | November 2010 | |
| NCT04506905 | Completed | Phase 1 | Safety, Tolerability, and Pharmacokinetics Study of MK-8189 in Participants With Schizophrenia and Healthy Participants (MK-8189-011) | August 28, 2020 | March 22, 2022 |
| NCT00007774 | Completed | Phase 4 | To Determine if Olanzapine is More Cost Effective Than Haloperidol for the Treatment of Schizophrenia | March 1998 | |
| NCT00216528 | Completed | Phase 4 | A Study to Evaluate Symptomatic Remission in Schizophrenia With Long Acting Risperidone Microspheres | July 2005 | April 2007 |
| NCT01942161 | Completed | Phase 2/Phase 3 | A Short Treatment Study of Aripiprazole in Pediatric Patients With Schizophrenia | August 2010 | November 2014 |
| NCT00129441 | Completed | Phase 2 | Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study | August 2005 | January 2008 |
| NCT01075295 | Completed | N/A | Prevention of Weight Gain in Early Psychoses | February 2010 | December 2012 |
| NCT02386605 | Completed | N/A | Motivational Negative Symptoms in Schizophrenia: Intervention and Biomarkers | March 28, 2016 | June 30, 2020 |
| NCT00304616 | Completed | Phase 4 | SWitching to Abilify Trial (SWAT) | October 2004 | October 2007 |
| NCT01175135 | Completed | Phase 2 | An Inpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Treatment Of Acute Exacerbation Of Schizophrenia | October 2010 | August 2011 |
| NCT04158167 | Completed | N/A | Neurobiological Effects of Oxytocin in Schizophrenia - Imaging Study | September 1, 2013 | December 30, 2018 |
| NCT00362804 | Completed | N/A | Tetrabenazine for Partial Responders | February 2002 | January 2006 |
| NCT00206557 | Completed | Phase 2 | The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study | October 2002 | April 2007 |
| NCT04251195 | Completed | N/A | Verbal Memory Training Using Virtual Reality in Schizophrenia | February 12, 2019 | February 17, 2023 |
| NCT04094207 | Completed | Phase 1/Phase 2 | Pentoxifylline as an Adjunctive in Treatment of Negative Symptoms in Chronic Schizophrenia | January 1, 2019 | September 30, 2022 |
| NCT02232529 | Completed | Phase 1 | Pharmacokinetic Study of MIN-101 in Healthy Subjects | September 2014 | February 2015 |
| NCT00212836 | Completed | Phase 3 | Efficacy and Safety of Asenapine Compared With Olanzapine in Patients With Persistent Negative Symptoms of Schizophrenia (25543)(COMPLETED)(P05817) | April 21, 2005 | August 2, 2007 |
| NCT00463372 | Completed | Phase 1 | Study Investigating the Safety and Tolerability of Multiple Doses of PF-02545920 in Subjects With Schizophrenia | October 2006 | May 2007 |
| NCT01044914 | Completed | Genes, Intermediate Phenotypes and Response to Quetiapine RX | December 2009 | October 2010 | |
| NCT00728728 | Completed | Phase 2 | Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia | December 2009 | December 2015 |
| NCT01318850 | Completed | N/A | Effects of Cognitive Remediation Therapy on Schizophrenia Patients Through Functional Magnetic Resonance Imaging | January 2008 | December 2010 |
| NCT01781000 | Completed | N/A | Cerebral Reorganization in Schizophrenia | December 2011 | April 2014 |
| NCT03860597 | Completed | Phase 4 | Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia | April 1, 2018 | March 31, 2021 |
| NCT02011750 | Completed | Phase 4 | Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii Infection in Early Course Schizophrenia | April 1, 2013 | December 31, 2017 |
| NCT00561561 | Completed | N/A | Sensorimotor Gating in Schizophrenia | June 2001 | August 26, 2011 |
| NCT01662310 | Completed | Phase 3 | An Efficacy Study of Paliperidone for the Prevention of Relapse in Participants With Schizophrenia | June 2011 | April 2013 |
| NCT00500201 | Completed | Phase 1 | A Healthy Volunteer Study to Assess the Relative Bioavailability of 2 Forms of SB773812 Tablets. | May 24, 2007 | July 25, 2007 |
| NCT00535132 | Completed | Phase 4 | Study to Measure Drug Satisfaction of Patients With Schizophrenia After Switching From Risperidone to Paliperidone | October 2007 | July 2008 |
| NCT00482430 | Completed | Phase 2 | MK0557 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0557-027) | September 2007 | October 2008 |
| NCT00814996 | Completed | Social Functioning in Schizophrenia | August 2008 | August 2008 | |
| NCT01622166 | Completed | N/A | Art Therapy in Acute Schizophrenia | August 2011 | January 2013 |
| NCT04078048 | Completed | N/A | Role of Antioxidants (Vitamin C and E) in the Management of Schizophrenia | April 27, 2017 | November 15, 2017 |
| NCT00140192 | Completed | Phase 3 | Creatine Treatment in Psychiatric Disorders | September 2004 | March 2006 |
| NCT01529515 | Completed | Phase 3 | A Study of Paliperidone Palmitate 3 Month Formulation for the Treatment of Patients With Schizophrenia | May 2012 | April 2014 |
| NCT00290121 | Completed | Phase 4 | Appetite Increase in Schizophrenia Patients Treated With Atypical Antipsychotics | September 2006 | June 2008 |
| NCT05500651 | Completed | N/A | Dance and Movement Therapy in Patients With Schizophrenia | September 1, 2022 | February 15, 2023 |
| NCT05779241 | Completed | Phase 3 | Study to Evaluate the Pharmacokinetics (PK) and Safety/Tolerability of Long-Acting Oral LYN-005 | April 13, 2023 | December 1, 2023 |
| NCT03281629 | Completed | N/A | Circuitry-Guided Smoking Cessation in Schizophrenia | October 19, 2018 | February 15, 2022 |
| NCT00151424 | Completed | Phase 3 | Efficacy and Safety of Asenapine With Placebo and Olanzapine (41022)(P05947) | February 15, 2005 | February 6, 2006 |
| NCT01401491 | Completed | Phase 4 | Treatment Strategy for Refractory Schizophrenia: Drug Interaction Between Clozapine and Fluvoxamine | January 2008 | December 2010 |
| NCT00034749 | Completed | Phase 3 | The Efficacy and Safety of Risperidone in the Treatment of Adolescents With Schizophrenia | April 2001 | March 2006 |
| NCT02411695 | Completed | Phase 1 | Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral Brexpiprazole (OPC- 34712) in Adolescents With Schizophrenia | March 2015 | January 2017 |
| NCT01559272 | Completed | Phase 1 | A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Paliperidone Palmitate in Patients With Schizophrenia | February 21, 2008 | May 24, 2014 |
| NCT01995864 | Completed | N/A | Critical Time Intervention-Task Shifting: Randomized Controlled Trial | February 2014 | June 1, 2020 |
| NCT00000374 | Completed | Phase 4 | Treatment for First-Episode Schizophrenia | September 1998 | May 2007 |
| NCT00458367 | Completed | RiSPECT: Risperdal Safety Protocol Evaluation Consta Treatment, a Post Authorization Safety Survey to Obtain Information on the Safety and Efficacy of Risperidone When Used in Routine Clinical Practice | June 2002 | October 2006 | |
| NCT01593774 | Completed | Phase 2 | Melatonin for Prevention of Metabolic Side Effects of Olanzapine | May 2012 | March 2013 |
| NCT00714818 | Completed | Phase 3 | Impact of Genetic Counseling for Female First Degree Relatives of Individuals With Mental Illness | August 2008 | November 2011 |
| NCT01545310 | Completed | Phase 1 | A Positron Emission Tomography Study of SLV354 in Healthy Subjects and Subjects With Schizophrenia | May 2011 | July 2012 |
| NCT01425684 | Completed | Brain Circuits in Schizophrenia and Smoking | December 20, 2010 | April 2021 | |
| NCT00567203 | Completed | Phase 1 | A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia | November 2007 | May 2008 |
| NCT02880462 | Completed | Phase 2 | A 6-month Study to Evaluate Sulforaphane add-on Effects in Treatment of Schizophrenia | December 26, 2016 | May 20, 2019 |
| NCT00752427 | Completed | Phase 3 | 24-Week Open Label Extension to a Randomized, 6-Week Double Blind, Placebo Controlled Study, to Evaluate the Safety and Tolerability of Flexible Doses of Extended Release OROS® Paliperidone in the Treatment of Geriatric Subjects With Schizophrenia | June 2004 | November 2005 |
| NCT01001702 | Completed | Phase 3 | Oral Aripiprazole Open-Label Rollover Study | April 2006 | July 2012 |
| NCT04115319 | Completed | Phase 3 | A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia. | November 15, 2019 | December 30, 2022 |
| NCT01081769 | Completed | Phase 3 | Prevention of Relapse With Injectable Paliperidone Palmitate Versus Oral Antipsychotics | February 2010 | February 2013 |
| NCT01614093 | Completed | Phase 4 | Effects of Intranasal Oxytocin on Satiety Signaling in People With Schizophrenia | June 2012 | January 2014 |
| NCT00567034 | Completed | Phase 1 | Augmenting Zyprexa With Naltrexone to Ameliorate Metabolic Side-Effects | December 2006 | December 2011 |
| NCT00934466 | Completed | Phase 1 | Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008) | July 2009 | December 2009 |
| NCT02906553 | Completed | N/A | The Role of Nitric Oxide in Cognition in Schizophrenia | September 2016 | April 2019 |
| NCT03621774 | Completed | N/A | Mobile CBT for Negative Symptoms | March 27, 2019 | August 31, 2022 |
| NCT00088075 | Completed | Phase 3 | Investigate Risperidone for the Treatment of Schizophrenia in Adolescents | August 2004 | December 2005 |
| NCT06043206 | Completed | Bariatric Surgery in Patients With Schizophrenia | October 1, 2022 | June 30, 2023 | |
| NCT01392482 | Completed | IBIS: Italian Burden of Illness on Schizophrenia & Bipolar Disorder | July 2011 | September 2012 | |
| NCT01325363 | Completed | N/A | Magnetoencephalographic (MEG) Evidence for Novel Metaphor Processing Among Schizophrenic Patients | April 2011 | December 2011 |
| NCT00349973 | Completed | N/A | Clinical Trial of Dipyridamole in Schizophrenia | May 2001 | September 2011 |
| NCT02685748 | Completed | Phase 2/Phase 3 | Aspirin in Young Psychotic Patients | July 20, 2017 | December 31, 2019 |
| NCT01629355 | Completed | Auditory Brainstem Response as a Diagnostic Tool in Schizophrenia and Bipolar Disorder | July 2012 | August 2015 | |
| NCT01556763 | Completed | Phase 1 | Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia | April 2008 | August 2008 |
| NCT00686101 | Completed | Knowledge and Perception of Smoking Risks/Consequences | December 2007 | June 2009 | |
| NCT00940394 | Completed | Phase 2 | Effectiveness of Family Group Interventions for People With Schizophrenia | January 2007 | December 2011 |
| NCT01410357 | Completed | N/A | Improving Outcomes for Individuals With Serious Mental Illness and Diabetes | July 2011 | July 2015 |
| NCT00102479 | Completed | Phase 2 | Aripiprazole Pharmacokinetics (PK) and Tolerability Study in Children and Adolescents | July 2004 | July 2005 |
| NCT00838669 | Completed | Phase 1 | A Study of the Effect of Food and Posture on the Pharmacokinetics of a Single Dose of ER OROS Paliperidone | August 2005 | December 2005 |
| NCT00158223 | Completed | Phase 4 | Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia | October 2004 | February 2009 |
| NCT05137158 | Completed | N/A | iTBS on Negative Symptoms and Cognitive Function in Schizophrenia | October 15, 2022 | June 14, 2024 |
| NCT00434980 | Completed | N/A | Family-Directed Cognitive Adaptation Program for Individuals With Schizophrenia | February 2005 | February 2015 |
| NCT00094640 | Completed | Phase 1 | Pharmacokinetic Characterization of Intramuscular Olanzapine Depot | ||
| NCT03663465 | Completed | N/A | The Effect of Hawthorn on Lipoprotein Cholesterol Ratio in Schizophrenics With Antipsychotics | January 1, 2013 | July 31, 2014 |
| NCT03189810 | Completed | N/A | Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cannabis Use and Cognitive Outcomes in Schizophrenia | June 1, 2017 | June 30, 2021 |
| NCT03345342 | Completed | Phase 3 | A Study of Paliperidone Palmitate 6-Month Formulation | November 20, 2017 | May 8, 2020 |
| NCT04990414 | Completed | Phase 2 | Cognitive Behaviour Therapy for Voices and Dissociation | November 24, 2013 | January 29, 2019 |
| NCT00205660 | Completed | Phase 4 | Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole | February 2005 | August 2009 |
| NCT00725075 | Completed | Phase 2 | Adjuvant Treatment With a Glycine Uptake Inhibitor in Participants With Negative Symptoms of Schizophrenia (P05695) (MK-8435-001) | April 10, 2007 | October 24, 2008 |
| NCT00235352 | Completed | Phase 2/Phase 3 | Trial of Ampakine Added to Clozapine, Olanzapine or Risperidone in Patients With Schizophrenia | February 2002 | February 2007 |
| NCT02716584 | Completed | N/A | Benefits of Physical Exercise in Schizophrenia | September 1, 2016 | July 12, 2018 |
| NCT00447941 | Completed | Phase 1 | Safety, PK and PD Study in Healthy Male Japanese Subjects | June 2006 | August 2006 |
| NCT00621777 | Completed | Phase 4 | A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder | February 2008 | May 2013 |
| NCT03568500 | Completed | Phase 4 | A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an Oral Atypical Antipsychotic | May 21, 2018 | September 6, 2019 |
| NCT00001544 | Completed | Genetic Aspects of Neurologic and Psychiatric Disorders | April 1996 | March 2004 | |
| NCT00090324 | Completed | Phase 3 | Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Adolescent Patients With Schizophrenia | September 2004 | June 2007 |
| NCT00210769 | Completed | Phase 3 | A Study of the Long-term Safety and Tolerability and the Long-term Effectiveness of Extended-release Oral Paliperidone in Patients Diagnosed With Schizophrenia | January 2004 | December 2005 |
| NCT03360695 | Completed | N/A | Bridge: Proactive Psychiatry Consultation and Case Management for Patients With Cancer | December 11, 2017 | December 1, 2022 |
| NCT02566356 | Completed | Early Phase 1 | Adult Study Oxytocin - fMRI | September 2012 | September 2017 |
| NCT00403247 | Completed | N/A | Effect of High-Dose B-Complex Vitamins on the Symptoms of Schizophrenia | July 2004 | July 2007 |
| NCT00264069 | Completed | ADH.E.R.E.: Therapeutic ADHerence and Treatment Strategies: A Mental Health Registry | June 2005 | June 2006 | |
| NCT03317769 | Completed | N/A | Creating Live Interactions to Mitigate Barriers | April 1, 2018 | June 6, 2019 |
| NCT00156637 | Completed | N/A | A Study of Strategies to Improve Schizophrenia Treatment | June 2005 | March 2008 |
| NCT00208143 | Completed | Phase 4 | Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia | November 2003 | December 2005 |
| NCT01315002 | Completed | N/A | Nicotine Effects on Endophenotypes of Schizophrenia | July 2008 | March 2012 |
| NCT03621540 | Completed | N/A | Augmentation of Working Memory Training With Transcranial Direct Current Stimulation in Patients With Schizophrenia | April 20, 2018 | May 30, 2023 |
| NCT01053429 | Completed | A Non-Interventional Post-Marketing Surveillance Study to Evaluate the Safety and Efficacy of Zeldox Capsule | June 2005 | February 2010 | |
| NCT03810755 | Completed | N/A | EfiKroniK Research Program: Physical Exercise for People With Chronic Pathologies | January 10, 2018 | December 31, 2022 |
| NCT00205738 | Completed | N/A | Janssen - Glucose Regulation/Risp/Olanz | July 2000 | October 2006 |
| NCT00677898 | Completed | N/A | A Patient-Centered Approach to Improve Screening for Side Effects of Second Generation Antipsychotics (SGAs) | March 2010 | June 2013 |
| NCT00805454 | Completed | Phase 1 | Positron Emission Tomagraphy (PET) Study Following a Single Oral Dose of OPC-34712 | December 2008 | July 2009 |
| NCT03425552 | Completed | Phase 1/Phase 2 | A Clinical Study to Evaluate the Bioavailability Between Two Products Containing Paliperidone 100 mg in the Form of a Prolonged Release Suspension for Injection in Patients With Schizophrenia Who Are Already Stabilized in This Treatment | March 11, 2018 | May 2, 2019 |
| NCT00448890 | Completed | Phase 1 | Evaluation of Single and Repeat Doses of GSK729327 in Healthy Volunteers | November 2006 | January 2009 |
| NCT01009047 | Completed | Phase 3 | An Efficacy and Safety Study of Extended-Release (ER) Paliperidone in Adolescent Participants With Schizophrenia | December 2009 | June 2012 |
| NCT02349880 | Completed | N/A | A Shared Decision-making Training for Inpatients With Schizophrenia | October 2011 | March 2015 |
| NCT00304655 | Completed | Phase 4 | Acute Psychosis Treatment in the Long Term, Unitary Group Study (APLUS) | July 2004 | October 2007 |
| NCT02121106 | Completed | N/A | Remote Cognitive Remediation | September 2013 | September 2016 |
| NCT01549041 | Completed | Phase 4 | Once-Daily Asenapine for Schizophrenia | April 2012 | November 2013 |
| NCT00297947 | Completed | Phase 2/Phase 3 | High Dose of Quetiapine in Treating Subjects With Treatment Refractory Schizophrenia or Schizoaffective Disorder | December 2004 | October 2014 |
| NCT04182113 | Completed | N/A | rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia | November 8, 2019 | June 30, 2022 |
| NCT00361166 | Completed | Phase 2 | Antipsychotic and Motor Effects of ACP-103 When Administered in Combination With Haloperidol and Risperidone | August 2005 | March 2007 |
| NCT06326840 | Completed | N/A | Clinical Efficacy and Adverse Reactions of Antipsychotic Treatment | May 31, 2010 | June 10, 2011 |
| NCT02069925 | Completed | N/A | STEP-ED: Reducing Duration of Untreated Psychosis and Its Impact in the U.S. | February 1, 2014 | August 18, 2020 |
| NCT05486312 | Completed | N/A | 7-week Study With CT-155 in People With Schizophrenia | July 5, 2022 | December 12, 2022 |
| NCT02892422 | Completed | Phase 3 | Flexible-dose, Long-term Safety Study of Lu AF35700 in Adult Patients With Schizophrenia | August 2016 | October 10, 2019 |
| NCT01561859 | Completed | N/A | Brain Imaging, Cognitive Enhancement and Early Schizophrenia | June 2012 | June 2018 |
| NCT00763438 | Completed | Phase 4 | Safety Study of an Antipsychotic, Sertindole, to Treat Schizophrenia | November 2007 | October 2010 |
| NCT04703530 | Completed | N/A | Effect of Hot Footbath on the Sleep Quality | December 1, 2019 | July 31, 2020 |
| NCT01527305 | Completed | Phase 4 | A Study to Evaluate the Effectiveness and Safety of Paliperidone Palmitate in Subjects With Acute Schizophrenia | June 2012 | December 2013 |
| NCT00515671 | Completed | N/A | Illness Management and Recovery for Veterans With Severe Mental Illness | January 2008 | September 2013 |
| NCT03662425 | Completed | N/A | Effects of Oxytocin on Negative Symptoms and Social Cognition in Schizophrenia and Its Possible Mechanisms | July 21, 2018 | March 31, 2020 |
| NCT03379597 | Completed | N/A | A 12-weeks Study to Evaluate the Dietary Fiber and Probiotics Treatment in Prevention and Intervention of Weight-gain and Cognitive Impairment of Schizophrenia or Bipolar Disorder | November 30, 2017 | June 30, 2021 |
| NCT04779177 | Completed | Phase 1 | Safety, Tolerability, and Pharmacokinetics of Lumateperone in Pediatric Patients With Schizophrenia or Schizoaffective Disorder | March 12, 2021 | July 30, 2022 |
| NCT01625897 | Completed | Phase 2/Phase 3 | A Long-Term Study of MP-214 in Patients With Chronic Phase or Elderly Schizophrenia | May 2012 | March 2015 |
| NCT02576613 | Completed | N/A | Modified Psychodynamic Psychotherapy for Patients With Schizophrenia | October 2015 | December 2022 |
| NCT00466323 | Completed | N/A | The Effectiveness of FMPO in Improving the Quality of Care for Persons With Severe Mental Illness. | September 2007 | June 2011 |
| NCT03280810 | Completed | N/A | Effects of a Psycho-corporal Training on Postural and Cognitive Dual-task Performances in Patients With Schizophrenia | December 2013 | December 2015 |
| NCT00330863 | Completed | Phase 4 | Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy | May 2006 | January 2011 |
| NCT04240496 | Completed | N/A | Clinical and Genetic Influencing Factors on Clozapine Pharmacokinetics | October 17, 2019 | December 14, 2019 |
| NCT00520650 | Completed | Phase 4 | Health Evaluation of Abilify Long-term Therapy | August 2006 | April 2009 |
| NCT00302432 | Completed | N/A | The Effect of Cigarette Holders, Plastic Menthol Cigarettes, and Cognitive Behavioral Therapy for Smoking Reduction Among Schizophrenia Inpatients: A Comparative Study | March 2006 | December 2007 |
| NCT00155649 | Completed | A Positional Cloning Study on Schizophrenia | April 2002 | April 2005 | |
| NCT00419016 | Completed | Association Between Schizophrenia and Cancer | |||
| NCT04987229 | Enrolling by invitation | Phase 3 | Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects | October 22, 2021 | September 2027 |
| NCT05304767 | Enrolling by invitation | Phase 3 | An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia | March 7, 2022 | February 2026 |
| NCT05100888 | Enrolling by invitation | N/A | Theta-burst rTMS in Schizophrenia to Ameliorate Negative and Cognitive Symptoms | July 11, 2022 | December 1, 2025 |
| NCT05703412 | Enrolling by invitation | N/A | Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness | February 14, 2023 | July 31, 2027 |
| NCT06440200 | Enrolling by invitation | N/A | Exploring the Health Effects of Group Game-based Activities on Individuals With Chronic Mental Illness | January 18, 2024 | August 30, 2024 |
| NCT04554121 | Enrolling by invitation | N/A | Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing | December 14, 2020 | May 1, 2025 |
| NCT05127837 | Enrolling by invitation | N/A | CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies | June 28, 2022 | February 12, 2024 |
| NCT05741528 | Enrolling by invitation | Phase 3 | An Extension Study to a Clinical Study That Will Continue to Evaluate the Effectiveness and Safety of SEP-363856 in People With Schizophrenia That Switch to SEP-363856 From Their From Their Current Antipsychotic Medication | March 31, 2023 | January 10, 2025 |
| NCT05567848 | Enrolling by invitation | Phase 1/Phase 2 | Accelerated TMS in Psychosis | November 29, 2022 | January 2025 |
| NCT01088386 | Enrolling by invitation | Zyprexa® Relprevv™ Patient Care Program | March 2010 | June 2026 | |
| NCT04323566 | Enrolling by invitation | Phase 2 | Rituximab Treatment for Psychosis and/or Obsessive Compulsive Disorder With Probable Immune System Involvement | May 1, 2022 | May 1, 2026 |
| NCT05784961 | Not yet recruiting | N/A | Impact of tDCS on Cannabis Craving in Schizophrenia | March 1, 2024 | June 20, 2027 |
| NCT05457127 | Not yet recruiting | N/A | Obstructive Sleep Apnea Treatment in Serious Mental Illness | January 1, 2024 | November 2026 |
| NCT06278246 | Not yet recruiting | Investigating the Muscarinic System in Schizophrenia Using Positron Emission Tomography | February 2024 | February 2029 | |
| NCT05165316 | Not yet recruiting | European Long-acting Antipsychotics in Schizophrenia Trial-II | December 2021 | August 2025 | |
| NCT06456983 | Not yet recruiting | N/A | Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST Trial | April 2025 | July 2028 |
| NCT05528146 | Not yet recruiting | N/A | Effects of Psyllium on Constipation in Schizo-phrenic: A Randomized Controlled Crossover Trial | December 1, 2022 | August 31, 2023 |
| NCT03543553 | Not yet recruiting | From Brain Currents to Interpersonal Flow: Investigating the Social Processing Stream of Schizophrenia | January 1, 2025 | March 31, 2027 | |
| NCT05866107 | Not yet recruiting | N/A | App and Body Fat Scale in the Management of Overweight Patients | October 15, 2023 | December 31, 2024 |
| NCT05823805 | Not yet recruiting | N/A | Approaches For ThE pRioritization of Patients in priMAry Care Post-COVID To Reduce Health Inequities (AFTERMATH) | March 2024 | March 2025 |
| NCT06060886 | Not yet recruiting | Phase 4 | Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis | November 1, 2023 | December 31, 2025 |
| NCT05770375 | Not yet recruiting | Phase 1/Phase 2 | Tolerability of MDMA in Schizophrenia | August 1, 2024 | March 2026 |
| NCT06251193 | Not yet recruiting | N/A | Optimizing CBSST With Executive Function Training for Schizophrenia | March 15, 2024 | February 1, 2027 |
| NCT06303596 | Not yet recruiting | N/A | Hippotherapy in Patients With Schizophrenia | March 20, 2024 | October 1, 2024 |
| NCT06155682 | Not yet recruiting | N/A | TMS for Inhibition Enhancement in Schizophrenia | March 2025 | December 2028 |
| NCT06142422 | Not yet recruiting | N/A | Intermittent Theta Burst Stimulation of the Precuneus | April 2024 | June 2026 |
| NCT02670447 | Not yet recruiting | Early Identification of Patients Presenting a First Psychotic Episode, Non Answering to First Line Support Strategies | September 2024 | August 2030 | |
| NCT06284096 | Not yet recruiting | N/A | The Personal Recovery Based Psychoeducation For Schizophrenia | June 2024 | June 2024 |
| NCT06397950 | Not yet recruiting | Correlates of Fatigue in People With Schizophrenia | May 2024 | August 2025 | |
| NCT03575000 | Not yet recruiting | Phase 4 | Bromocriptine for Patients With Schizophrenia and Prediabetes | July 1, 2024 | April 30, 2026 |
| NCT05948111 | Not yet recruiting | Assessment of Schizophrenia Patients' Clinical Study Experiences | August 2024 | August 2026 | |
| NCT05469815 | Not yet recruiting | N/A | Lost Children Society (LCS), Online Therapeutic Tabletop Role-playing Game for Early-onset Schizophrenia Patients | September 1, 2024 | January 1, 2026 |
| NCT05778591 | Not yet recruiting | Phase 2 | Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia | June 1, 2024 | April 1, 2025 |
| NCT06043778 | Not yet recruiting | N/A | Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India | January 2025 | December 2028 |
| NCT04332601 | Not yet recruiting | N/A | Assessment of the Efficacy of a Fatigue Management Therapy in Schizophrenia | February 2022 | November 2025 |
| NCT05440955 | Not yet recruiting | N/A | tDCS for Cognitive Impairment Associated With Recent-onset Schizophrenia | June 1, 2023 | June 1, 2027 |
| NCT04655235 | Not yet recruiting | Translational Investigation of the Glutamatergic and GABAergic System in Schizophrenia | June 1, 2022 | March 2030 | |
| NCT06345963 | Not yet recruiting | N/A | Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1) | May 1, 2024 | May 1, 2030 |
| NCT06107764 | Not yet recruiting | N/A | Cerebellar Modulation of Cognition in Psychosis | April 2024 | December 2029 |
| NCT06184165 | Not yet recruiting | N/A | Stratifying Psychoses for Personalized REpetitive TMS in Persistent NEgative Symptoms Alleviation | March 1, 2024 | November 1, 2028 |
| NCT06384521 | Not yet recruiting | N/A | Lifestyle MIND- Feasibility of Wait-list Control | June 2024 | May 2025 |
| NCT06208176 | Not yet recruiting | N/A | HD-tDCS for Hallucinations | February 28, 2024 | July 30, 2028 |
| NCT06315972 | Not yet recruiting | Phase 2 | Combining Clemastine and Aerobic Exercise to Treat Cognitive Dysfunction in Schizophrenia by Targeting Myelin Plasticity | April 2024 | April 2028 |
| NCT05416658 | Not yet recruiting | N/A | Shared Decision Making for Antipsychotic Medications | January 1, 2025 | June 30, 2025 |
| NCT05974527 | Not yet recruiting | Phase 4 | Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in the Emergency Department | September 1, 2023 | June 30, 2026 |
| NCT05731414 | Not yet recruiting | N/A | Outcomes From Remediation and Behavioural Intervention Techniques | March 1, 2023 | January 31, 2027 |
| NCT05978921 | Not yet recruiting | N/A | Physical Exercise in Patients With Schizophrenia | March 1, 2024 | May 1, 2024 |
| NCT05580211 | Not yet recruiting | N/A | Neuromodulation for Schizophrenia | October 15, 2022 | January 30, 2026 |
| NCT04798131 | Not yet recruiting | N/A | fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations | December 2022 | July 2026 |
| NCT06361407 | Not yet recruiting | N/A | Sensory and Cognitive Predictions, and Their Disruptions in Schizophrenia | May 1, 2024 | February 28, 2028 |
| NCT05870722 | Not yet recruiting | An In Depth Study Evaluating The Experiences of Patients In Schizophrenia Research | June 2024 | June 2026 | |
| NCT05964790 | Not yet recruiting | Phase 1/Phase 2 | Safety, Tolerability, Pharmacokinetics and Efficacy Study of HS-10380 in Patients With Schizophrenia | July 30, 2023 | December 30, 2024 |
| NCT06275451 | Not yet recruiting | Qualitative Study of Emotional Regulation in Schizophrenia | February 2024 | January 2026 | |
| NCT06347848 | Not yet recruiting | N/A | The Effect of Psychoeducation Focused on Reducing Internalized Stigma | April 30, 2024 | September 1, 2024 |
| NCT06376734 | Not yet recruiting | Phase 2 | Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness | June 1, 2024 | June 1, 2030 |
| NCT05808244 | Not yet recruiting | N/A | Tele-group Cognitive Behavioural Family Intervention (tgCBFI) for People With Schizophrenia and Their Families | April 2023 | February 2024 |
| NCT05850585 | Not yet recruiting | N/A | A Study of the Efficacy of Fecal Microbiota Transplantation(FMT) in the Treatment of Schizophrenia | July 2023 | December 2026 |
| NCT05448430 | Not yet recruiting | N/A | iTBS Can Increase Frontal Dopamine Release in PET Dopamine Imaging. | July 15, 2022 | July 1, 2024 |
| NCT06286202 | Not yet recruiting | N/A | Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial | May 2024 | July 2027 |
| NCT05725785 | Not yet recruiting | N/A | Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness | June 1, 2023 | March 31, 2025 |
| NCT06386588 | Not yet recruiting | N/A | The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia | May 1, 2024 | December 31, 2027 |
| NCT06442462 | Not yet recruiting | Phase 2 | Study of SPG302 in Adults With Schizophrenia | July 2024 | October 2025 |
| NCT06340789 | Not yet recruiting | Phase 2 | Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate | April 10, 2024 | April 30, 2025 |
| NCT06058702 | Not yet recruiting | Phase 1 | Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans | July 1, 2024 | December 31, 2028 |
| NCT06115200 | Not yet recruiting | Norwegian Adult Mental Health Registry | January 1, 2024 | December 31, 2030 | |
| NCT03974620 | Not yet recruiting | N/A | Individual Placement and Support and/or Cognitive Remediation Therapy Added to TAU in Patients With Early Schizophrenia | December 1, 2024 | December 30, 2024 |
| NCT06301074 | Not yet recruiting | Phase 1 | The Phase I Study of HS-10509 in Chinese Adult Subjects | March 2024 | October 2024 |
| NCT05435300 | Recruiting | Does tDCS Change Synaptic Density in the Brains of Patients With Schizophrenia | September 17, 2021 | September 2024 | |
| NCT06197048 | Recruiting | N/A | Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psychosis or Bipolar Affective Disorder | September 25, 2023 | December 1, 2028 |
| NCT05939765 | Recruiting | Pharmacologic Treatment in Legal Offenders With Schizophrenia, a Prospective Observational Mirror Image Study. | August 2, 2023 | April 30, 2025 | |
| NCT06276361 | Recruiting | Phase 1 | Pharmacokinetics, Safety and Tolerability of Different Formulations and Dose Strengths of Quarterly Risperidone (QUAR) in Patients With Schizophrenia | September 26, 2023 | May 2026 |
| NCT05102929 | Recruiting | N/A | Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia | November 5, 2021 | August 2026 |
| NCT05358899 | Recruiting | N/A | Accelerated cTBS on Metabolic Dysfunction in People With Schizophrenia | June 1, 2022 | May 1, 2023 |
| NCT04038840 | Recruiting | Phase 1 | Imaging Synapses With [11C] UCB-J in the Human Brain | August 1, 2019 | December 2025 |
| NCT04352569 | Recruiting | N/A | Efficacy of tDCS in the Treatment of Resistant Auditory Hallucinations in Schizophrenia | May 3, 2016 | March 10, 2026 |
| NCT04857983 | Recruiting | Phase 2/Phase 3 | Memantine Augmentation of Targeted Cognitive Training in Schizophrenia | July 6, 2021 | December 30, 2024 |
| NCT03943537 | Recruiting | Phase 2 | Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders | October 1, 2019 | January 26, 2024 |
| NCT05766007 | Recruiting | Long-acting Injectable Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum | August 1, 2023 | August 2025 | |
| NCT05299749 | Recruiting | N/A | Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations | March 1, 2022 | June 30, 2025 |
| NCT06446856 | Recruiting | EVEN - Effects of VR on Empathy for Nature in Patients With Psychosis and Depressive Disorders | May 27, 2024 | August 1, 2024 | |
| NCT04298450 | Recruiting | N/A | ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention | September 21, 2020 | December 2025 |
| NCT05030272 | Recruiting | N/A | Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings | September 21, 2021 | April 1, 2025 |
| NCT06066112 | Recruiting | Phase 1 | Study on the Bioequivalence of Amisulpride Orally Disintegrating Tablets in Human Body | September 20, 2023 | March 31, 2024 |
| NCT05303064 | Recruiting | Phase 3 | Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder | June 30, 2022 | September 2026 |
| NCT05227690 | Recruiting | Phase 2 | A Trial of 10 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia | June 30, 2022 | December 2024 |
| NCT06003036 | Recruiting | N/A | Accelerated Transcranial Magnetic Stimulation for People With Schizophrenia Treated With Clozapine | December 1, 2023 | September 2025 |
| NCT05966610 | Recruiting | Bizarreness and Anomalous Self Experiences in Schizophrenia | July 12, 2023 | September 1, 2024 | |
| NCT05951660 | Recruiting | N/A | Sex, Psychopharmacology, and Diabetes | August 24, 2023 | July 31, 2025 |
| NCT05542212 | Recruiting | N/A | Intra-cortical Inhibition and Cognitive Deficits in Schizophrenia | September 28, 2022 | February 2024 |
| NCT03817502 | Recruiting | Phase 3 | Efficacy and Safety of Cariprazine in the Treatment of Adolescent Participants (13 to 17 Years of Age) With Schizophrenia | June 6, 2019 | April 1, 2025 |
| NCT04278339 | Recruiting | N/A | Study of Electrophysiological Markers Related to the Cognitive and Affective Processes Behind Empathic Behaviour in Schizophrenic Spectrum Disorder | October 10, 2020 | October 2025 |
| NCT01392885 | Recruiting | Brain Health and Exercise in Schizophrenia | July 2011 | December 2026 | |
| NCT05023252 | Recruiting | N/A | Mobile Self-Tracking | October 18, 2021 | September 30, 2024 |
| NCT05686239 | Recruiting | Phase 2 | A Study to Evaluate RL-007 in the Treatment of Cognitive Impairment Associated With Schizophrenia (CIAS) | December 8, 2022 | November 15, 2024 |
| NCT00178932 | Recruiting | N/A | Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors | November 1998 | December 2023 |
| NCT06159322 | Recruiting | Characterizing Response to Antipsychotics in Schizophrenia | January 1, 2023 | January 30, 2024 | |
| NCT04226898 | Recruiting | Phase 2 | Synbiotic Compound to Reduce Symptoms of Schizophrenia | February 21, 2022 | January 2025 |
| NCT04887792 | Recruiting | Phase 1/Phase 2 | Acetazolamide for Treatment Resistant Schizophrenia | February 1, 2022 | June 30, 2025 |
| NCT05268809 | Recruiting | N/A | Can Neural Network Instability in Schizophrenia be Improved With a Very Low Carbohydrate Ketogenic Diet? | April 21, 2022 | February 2025 |
| NCT05491538 | Recruiting | N/A | Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness | December 1, 2022 | November 30, 2024 |
| NCT04086160 | Recruiting | N/A | Effects of Transcranial Direct Current Stimulation (tDCS) on Motor Function in Schizophrenia Patients and Individuals at Risk for Psychotic Onset | August 22, 2019 | December 31, 2023 |
| NCT05599373 | Recruiting | N/A | Optimal rTMS for Cognitive Deficits and Negative Symptoms in Schizophrenia | January 1, 2020 | December 31, 2023 |
| NCT04144231 | Recruiting | N/A | Cognitive Behavioral Therapy for Insomnia (CBT-I) in Schizophrenia(SLEEPINS) | December 19, 2019 | September 6, 2024 |
| NCT05838560 | Recruiting | Phase 2 | Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders | July 1, 2023 | May 1, 2026 |
| NCT05208190 | Recruiting | Phase 4 | Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial | March 17, 2022 | February 28, 2027 |
| NCT05911529 | Recruiting | N/A | Motivational Interviewing for Patients With Acute Psychosis | March 15, 2023 | November 30, 2023 |
| NCT02765880 | Recruiting | N/A | Time,Self and Spontaneous Mental Activities in Patients With Psychotic Disorders | March 16, 2017 | September 2025 |
| NCT03183609 | Recruiting | N/A | Confirmatory Efficacy Trial of a Gluten-Free Diet in a Subgroup of Persons With Schizophrenia Who Have High Levels of IgG Anti-Gliadin Antibodies (AGA IG) | July 10, 2017 | July 30, 2025 |
| NCT04629352 | Recruiting | N/A | Effect of Neuroplasticity Modulation in tDCS Treatment Response Among Schizophrenia Patients With Auditory Hallucination | December 1, 2020 | August 31, 2025 |
| NCT06182787 | Recruiting | Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient | May 18, 2022 | January 19, 2024 | |
| NCT05193578 | Recruiting | Phase 2 | Home-based Intervention With Semaglutide Treatment Of Neuroleptica-Related Prediabetes | January 1, 2022 | December 30, 2024 |
| NCT03271866 | Recruiting | N/A | Metformin Treatment on Cognitive Impairment of Schizophrenia Co-morbid Metabolic Syndrome | August 28, 2017 | December 31, 2023 |
| NCT05648591 | Recruiting | Phase 4 | Safety and Tolerability of Open-Labeled Iloperidone in Adolescents | May 24, 2023 | September 2024 |
| NCT05805397 | Recruiting | N/A | Effectiveness of Motivation Skills Training (MST) | April 15, 2024 | November 2025 |
| NCT05929352 | Recruiting | N/A | Song-making In a Group (SING) | October 14, 2022 | May 31, 2025 |
| NCT03432000 | Recruiting | N/A | Links Between Perception of Temporal Order Judgment and Causality in Schizophrenia | February 1, 2018 | December 31, 2022 |
| NCT05956951 | Recruiting | N/A | Restoring Spindle and Thalamocortical Efficiency in Early-Course Schizophrenia Patients Using Auditory Stimulation | July 20, 2023 | June 2028 |
| NCT06361667 | Recruiting | N/A | Culture and Well-being: Art as Prescription Therapy ("Art on Prescription") | March 20, 2024 | January 15, 2025 |
| NCT03140475 | Recruiting | Explorations of the Normal Neural Behavioral and Pathological Bases of Metacognition | April 27, 2017 | September 27, 2024 | |
| NCT05480046 | Recruiting | Non-interventional Study of Risperidone ISM® in Schizophrenia Patients Hospitalised Due to a Relapse | October 18, 2022 | June 2024 | |
| NCT02796859 | Recruiting | Phase 1/Phase 2 | Siltuximab in Schizophrenia | May 2016 | December 31, 2023 |
| NCT04917302 | Recruiting | Phase 2 | Combination of NMDA-enhancing and Anti-inflammatory Treatments for Schizophrenia | October 13, 2020 | December 2024 |
| NCT05838625 | Recruiting | Phase 3 | Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia | March 31, 2023 | July 18, 2025 |
| NCT05660018 | Recruiting | N/A | TMS Related Biomarker Assessments | January 7, 2023 | December 2028 |
| NCT05667961 | Recruiting | Predictors of Functional Remission in Discharged Patients With Schizophrenia After Long-term Drug Discontinuation | September 15, 2022 | December 2025 | |
| NCT06236048 | Recruiting | Energetics and Glutamate in Schizophrenia | March 1, 2024 | December 1, 2028 | |
| NCT05582980 | Recruiting | N/A | Online HD-tDCS Over the Left DLPFC During a Working Memory Task for Treating Negative Symptoms of Schizophrenia | June 15, 2020 | May 31, 2024 |
| NCT06231732 | Recruiting | N/A | The Hi-tACS on Cognitive Function in Patients With Schizophrenia: a Pilot Study | November 14, 2023 | June 1, 2024 |
| NCT02639702 | Recruiting | Phase 4 | Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia | August 2016 | December 2026 |
| NCT05211947 | Recruiting | Phase 3 | A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study | March 3, 2022 | February 24, 2026 |
| NCT05159349 | Recruiting | Mental Health During the Whole Life Cycle of Community Patients With Schizophrenia | December 1, 2021 | December 2024 | |
| NCT05109065 | Recruiting | Peripheral Immune System in Individuals With Schizophrenia | March 1, 2021 | June 1, 2025 | |
| NCT05240976 | Recruiting | Phase 2 | Combination of NMDA-enhancing and Anti-inflammatory Treatments for Ultra-resistant Schizophrenia | February 23, 2022 | March 2027 |
| NCT02926859 | Recruiting | Phase 2 | Enhancing Recovery in Early Schizophrenia | April 8, 2017 | December 2025 |
| NCT04745143 | Recruiting | Phase 2 | Monotherapy of an NMDA Enhancer for Schizophrenia | January 1, 2018 | December 2025 |
| NCT05973110 | Recruiting | N/A | Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis | July 31, 2023 | February 2026 |
| NCT05809401 | Recruiting | N/A | Pragmatic Assessment and Treatment for the Health System | November 13, 2019 | July 31, 2025 |
| NCT05877716 | Recruiting | N/A | EPI-MINN: Targeting Cognition and Motivation - National | May 30, 2023 | July 2025 |
| NCT02848885 | Recruiting | N/A | The Effects of tDCS on Illness Awareness in Schizophrenia | August 2016 | December 31, 2024 |
| NCT04414930 | Recruiting | Phase 2 | Pharmacologic Augmentation of Targeted Cognitive Training in Schizophrenia | November 9, 2020 | December 2024 |
| NCT05724953 | Recruiting | Phase 1 | Alexithymia Intervention for Suicide | October 1, 2023 | May 30, 2025 |
| NCT06336616 | Recruiting | N/A | Getting Out of the House: Using Behavioral Activation to Increase Community Participation | February 15, 2024 | December 2026 |
| NCT05670197 | Recruiting | Service User and Staff Views on Digital Remote Monitoring for Psychosis | November 1, 2022 | December 31, 2023 | |
| NCT05389345 | Recruiting | N/A | tDCS and Executive Function Training for Schizophrenia | May 1, 2021 | December 31, 2023 |
| NCT05783063 | Recruiting | N/A | iTBS for Increased Appetite Induced by Antipsychotics | August 1, 2023 | December 1, 2024 |
| NCT05340348 | Recruiting | N/A | Patientheque in Patients With a Psychosis . | July 25, 2022 | July 25, 2032 |
| NCT05074732 | Recruiting | Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study. | December 1, 2019 | December 31, 2027 | |
| NCT05956327 | Recruiting | N/A | Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training | September 29, 2023 | September 2026 |
| NCT05748990 | Recruiting | N/A | Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia | April 1, 2023 | April 1, 2025 |
| NCT02455193 | Recruiting | N/A | Neuronal Effects of Exercise in Schizophrenia | August 2014 | July 2025 |
| NCT01888627 | Recruiting | N/A | Integrated Care in Psychotic Disorders With Severe Mental Illness | May 2007 | December 2025 |
| NCT05919823 | Recruiting | Phase 3 | A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 Schizophrenia | May 29, 2023 | May 2025 |
| NCT05664594 | Recruiting | N/A | State Representation in Early Psychosis - Project 4 | July 31, 2022 | March 31, 2025 |
| NCT05316883 | Recruiting | Phase 4 | Biomarkers in Clozapine-responding Schizophrenia | February 28, 2021 | December 31, 2024 |
| NCT05296720 | Recruiting | N/A | EEG and Behavioral Correlates of Temporal Prediction in the Tactile Modality in Schizophrenia | April 13, 2023 | October 2025 |
| NCT05473741 | Recruiting | Risk of Breakthrough Symptoms With Long-Acting Injectable Medications | January 9, 2023 | December 31, 2025 | |
| NCT06007105 | Recruiting | N/A | SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities | July 18, 2023 | January 31, 2024 |
| NCT05341804 | Recruiting | N/A | Cognitive and Balance Dual Task Training for People With Schizophrenia | May 10, 2022 | July 31, 2024 |
| NCT06226779 | Recruiting | N/A | Baduanjin Versus Brisk Walking for Cognition in Schizophrenia | January 16, 2024 | February 15, 2025 |
| NCT05110157 | Recruiting | Phase 3 | Journey Study: Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as Adjunctive Treatment for Schizophrenia | November 29, 2021 | September 2024 |
| NCT03873922 | Recruiting | N/A | Ketogenic Diet for Psychotic Disorders | March 15, 2021 | December 31, 2025 |
| NCT04916626 | Recruiting | N/A | The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis | May 6, 2021 | September 2025 |
| NCT05036590 | Recruiting | N/A | Efficiency Assessment of BREFORM. A Multicentric Stepped-wedge Randomized Control Trial. | April 5, 2022 | December 31, 2024 |
| NCT03601026 | Recruiting | N/A | Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use | November 1, 2019 | September 1, 2024 |
| NCT03794076 | Recruiting | Phase 1/Phase 2 | Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia | April 1, 2019 | August 2024 |
| NCT04871048 | Recruiting | N/A | Examining tDCS Effect on Cannabis Use Disorder in Patients With Schizophrenia | February 15, 2023 | March 1, 2026 |
| NCT04892199 | Recruiting | Phase 4 | Does GLP-1RA Prevent Deterioration of Metabolic State in Prediabetic and Diabetic Patients Treated With Antipsychotic Medication? | September 1, 2021 | December 31, 2024 |
| NCT04986072 | Recruiting | Phase 2 | Sodium Nitroprusside in Early Course Schizophrenia | March 14, 2022 | December 22, 2024 |
| NCT06236451 | Recruiting | Phase 4 | Atypical Antipsychotic-induced Mitochondrial Dysfunction in Patients With Schizophrenia | April 5, 2024 | September 30, 2025 |
| NCT05025605 | Recruiting | Phase 1 | Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder | August 27, 2021 | July 31, 2024 |
| NCT00024622 | Recruiting | PET Scanning in Parkinson s Disease | March 15, 2002 | ||
| NCT04580134 | Recruiting | Phase 4 | CLOZAPINE Response in Biotype-1 | March 1, 2022 | March 31, 2026 |
| NCT04859504 | Recruiting | N/A | Developing Dual-channel Transcranial Alternating Current Stimulations Targeting Negative Symptoms in Schizophrenia | April 1, 2021 | December 31, 2024 |
| NCT05968638 | Recruiting | N/A | Ketogenic Diet in People With Schizophrenia | September 1, 2023 | August 1, 2027 |
| NCT05273164 | Recruiting | N/A | State Representation in Early Psychosis | December 1, 2021 | March 31, 2025 |
| NCT06044038 | Recruiting | N/A | Exercise Intervention for People With Schizophrenia (CREW) | December 1, 2017 | December 31, 2025 |
| NCT04318977 | Recruiting | N/A | rTMS Add on Value for Amelioration of Negative Symptoms of Schizophrenia | February 1, 2020 | April 30, 2024 |
| NCT05351736 | Recruiting | Phase 4 | Impact of Structural and Myelin Abnormalities on Cognitive Impairments in Recent-onset Schizophrenia - Before and After Lurasidone Treatment (MARYLU) | January 26, 2022 | April 28, 2024 |
| NCT05389787 | Recruiting | N/A | Impact of Cerebellar TMS on Brain and Cognitive Functions in Schizophrenia: a Pilot Study | August 18, 2022 | August 31, 2025 |
| NCT04368039 | Recruiting | N/A | Normobaric Oxygen Therapy for Individuals With First-Episode Psychosis | December 4, 2019 | December 7, 2025 |
| NCT06118268 | Recruiting | N/A | iTBS to Enhance Social Cognition in People With Psychosis | April 18, 2023 | April 2027 |
| NCT04940663 | Recruiting | N/A | Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness | July 13, 2022 | June 2026 |
| NCT03814967 | Recruiting | N/A | Effects of Brain Stimulation on Higher-Order Cognition | May 22, 2019 | June 30, 2024 |
| NCT06021197 | Recruiting | Phase 2 | NMDA-enhancing Treatment for Cognitive Dysfunction of Schizophrenia | October 12, 2023 | March 2028 |
| NCT04004416 | Recruiting | Phase 4 | Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis | January 16, 2020 | February 28, 2025 |
| NCT06155786 | Recruiting | N/A | Cognitive Effects of tDCS and tRNS in Schizophrenia | January 1, 2023 | February 22, 2024 |
| NCT01730781 | Recruiting | Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning | July 2010 | December 2024 | |
| NCT05276050 | Recruiting | N/A | Circuitry-Guided Smoking Cessation in Schizophrenia (UH3) | June 1, 2022 | June 30, 2026 |
| NCT06045897 | Recruiting | N/A | EEG Microstates Across At-Risk Mental States | May 30, 2023 | July 30, 2026 |
| NCT06176456 | Recruiting | N/A | Personalized Prospective Study Evaluation of the Efficacy and Safety of Noninvasive Neuromodulation of TMS in Subjects With Catatonia | November 1, 2023 | November 1, 2024 |
| NCT05756855 | Recruiting | N/A | Young Adults With Violent Behavior During Early Psychosis | March 19, 2024 | August 2027 |
| NCT05698589 | Recruiting | N/A | COMpassion for Psychiatric Disorders And Self-Stigma | April 3, 2023 | March 1, 2028 |
| NCT06315283 | Recruiting | Phase 1 | An Open-Label Trial to Assess the Comparative Bioavailability of TV-44749 to Oral Olanzapine in Participants With Schizophrenia | March 20, 2024 | April 15, 2025 |
| NCT05464563 | Recruiting | N/A | Study by Electroencephalography of the Link Between the Lack of Self-compassion and the Disorder of Empathy in Schizophrenia | March 22, 2022 | March 2025 |
| NCT05724810 | Recruiting | N/A | Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia | April 4, 2023 | August 31, 2028 |
| NCT06002958 | Recruiting | N/A | Horyzons: Implementation and Integration in Clinical Practice | January 8, 2024 | October 31, 2024 |
| NCT04929795 | Recruiting | N/A | Effects of Music Beat on Motor Function in Individuals at Risk for Psychotic Onset and Schizophrenia Patients | August 11, 2021 | December 31, 2023 |
| NCT06407154 | Recruiting | Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study, 2nd Wave | May 21, 2024 | September 30, 2024 | |
| NCT06423651 | Recruiting | N/A | Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum Disorders | September 1, 2022 | December 31, 2025 |
| NCT03971487 | Recruiting | Phase 1/Phase 2 | Ocrelizumab for Psychosis by Autoimmunity | October 1, 2019 | October 30, 2025 |
| NCT04414215 | Recruiting | N/A | Cognitive Training for Emotion Regulation in Psychotic Disorders | June 1, 2020 | December 31, 2023 |
| NCT04296604 | Recruiting | N/A | Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations | September 2014 | September 2024 |
| NCT05859698 | Recruiting | Phase 4 | Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia | May 25, 2023 | December 2024 |
| NCT05204407 | Recruiting | N/A | Luteolin for the Treatment of People With Schizophrenia | June 13, 2022 | March 2025 |
| NCT05945277 | Recruiting | N/A | Critical Time Intervention-Peer Support | July 1, 2023 | December 31, 2025 |
| NCT04497857 | Recruiting | N/A | Academic-Community EPINET (AC-EPINET) | March 16, 2022 | August 31, 2024 |
| NCT05838573 | Recruiting | Phase 3 | Metformin Treatment on Cognitive Impairment of Schizophrenia | May 8, 2023 | December 30, 2025 |
| NCT05662306 | Recruiting | Phase 4 | C-Cog in Early Course Schizophrenia Study | January 23, 2024 | July 31, 2025 |
| NCT06179108 | Recruiting | Phase 2 | Randomized, Double-blinded, Placebo-controlled, Evaluating the Treatment With LB-102 in Patients With Acute Schizophrenia | December 4, 2023 | December 31, 2025 |
| NCT06225115 | Recruiting | Phase 1 | A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of KYN-5356 in Healthy Subjects Aged 18 to 55 Years | December 21, 2023 | July 2024 |
| NCT05328518 | Recruiting | Soft Tissue Tenderness and Fibromyalgia Among Schizophrenia Patients. | June 10, 2021 | September 10, 2024 | |
| NCT00004571 | Recruiting | Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers | February 17, 2000 | ||
| NCT06005766 | Recruiting | N/A | The Efficacy of Metacognitive Skills Training in the Context of Forensic Psychiatric Care | September 1, 2023 | December 2026 |
| NCT05017532 | Recruiting | N/A | Cognitive Remediation for Social Cognition in Schizophrenia and Related Disorders | January 6, 2022 | December 2024 |
| NCT05310955 | Recruiting | N/A | Intervention Effect of Shen-based Qigong Exercise on Residual Symptoms of Schizophrenia | August 16, 2022 | June 2023 |
| NCT04118283 | Recruiting | N/A | Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness | March 18, 2021 | January 31, 2025 |
| NCT03314129 | Recruiting | N/A | Remediation of Visual Perceptual Impairments in People With Schizophrenia | June 1, 2018 | August 31, 2025 |
| NCT05329363 | Recruiting | N/A | Evaluation of the Individual Early Psychoeducation Program for Schizophrenic Disorders in Inpatients | June 17, 2022 | June 2027 |
| NCT04578756 | Recruiting | Phase 3 | Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder | February 1, 2021 | September 15, 2025 |
| NCT02874573 | Recruiting | Phase 1 | Tocilizumab in Schizophrenia | September 2016 | December 31, 2023 |
| NCT06036316 | Recruiting | N/A | Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients With Psychosis | January 23, 2024 | January 23, 2026 |
| NCT05823532 | Recruiting | Phase 4 | Anti-Inflammatory Challenge in Schizophrenia | April 18, 2024 | March 2028 |
| NCT04099940 | Recruiting | N/A | Virtual Reality Avatar Therapy for People Hearing Voices | July 1, 2021 | December 31, 2025 |
| NCT04807530 | Recruiting | N/A | Medial-prefrontal Enhancement During Schizophrenia Systems Imaging | November 12, 2020 | December 30, 2026 |
| NCT06245213 | Recruiting | Phase 2 | A Study of ANAVEX3-71 in Adults With Schizophrenia | March 15, 2024 | May 15, 2025 |
| NCT04005794 | Recruiting | N/A | Virtual Reality Training for Social Skills in Schizophrenia - Comparison With Cognitive Training | October 15, 2021 | December 30, 2023 |
| NCT05157620 | Recruiting | N/A | Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness | October 24, 2022 | February 27, 2026 |
| NCT04681807 | Recruiting | N/A | Social Cognition in Youth Who Have a First Degree Relative With Schizophrenia | July 21, 2021 | October 31, 2024 |
| NCT04752449 | Recruiting | N/A | Virtual Cognitive Behavioural Therapy for Psychosis | February 1, 2021 | October 2023 |
| NCT05598450 | Recruiting | N/A | rTMS for Auditory Hallucinations Guided by Magnetoencephalography | July 1, 2023 | December 2025 |
| NCT02640911 | Recruiting | An Observational Study on Atypical Antipsychotics Long-term Treatment Patients With Schizophrenia | November 2010 | May 2033 | |
| NCT05635266 | Recruiting | Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives | October 26, 2021 | October 2025 | |
| NCT03649581 | Recruiting | N/A | Investigation of Neurophysiological Markers, Possibly Specific of Two Subforms of Psychotic Disorders | February 28, 2019 | February 2, 2027 |
| NCT06304233 | Recruiting | The Protein Disrupted in Schizophrenia 1 (DISC1) as a Novel Biomarker for Cardiac Disease | December 13, 2023 | June 2038 | |
| NCT04761861 | Recruiting | Phase 2 | Vildagliptin for Treatment of Antipsychotic-induced Dyslipidemia | February 16, 2021 | December 31, 2025 |
| NCT05380583 | Recruiting | N/A | Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study | May 19, 2022 | June 30, 2025 |
| NCT04011774 | Recruiting | N/A | Planning Your Everyday Life in Virtual Reality : a Study in Schizophrenia; | October 9, 2018 | August 9, 2024 |
| NCT03217110 | Recruiting | N/A | Cerebellar Stimulation and Cognitive Control | November 30, 2017 | August 1, 2024 |
| NCT04143126 | Recruiting | N/A | Promoting Activity and Cognitive Enrichment in Schizophrenia (PACES) | October 1, 2019 | June 30, 2025 |
| NCT04013555 | Recruiting | Phase 1/Phase 2 | The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia | January 20, 2020 | June 30, 2024 |
| NCT04911010 | Recruiting | N/A | Effectiveness of Trauma Therapy in Patients With PTSD and Comorbid Psychotic Disorder | January 20, 2021 | September 2025 |
| NCT00001486 | Recruiting | Genetic Study of Schizophrenia | July 15, 1995 | ||
| NCT05527210 | Recruiting | N/A | Prebiotic Treatment in People With Schizophrenia | January 25, 2023 | January 31, 2026 |
| NCT05643196 | Recruiting | Phase 2 | Focused Ultrasound Modulation of the Globus Pallidus Interna in Schizophrenia | April 6, 2023 | August 7, 2024 |
| NCT05824117 | Recruiting | N/A | Enhancing Educational and Vocational Recovery in Adolescents and Young Adults With Early Psychosis Through Supported Employment and Education. | October 18, 2022 | March 31, 2025 |
| NCT05443724 | Recruiting | Phase 2 | A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia | September 2, 2022 | February 2026 |
| NCT05326347 | Recruiting | Phase 3 | A Long-term Administration Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With Schizophrenia | May 31, 2022 | July 2025 |
| NCT06067984 | Recruiting | Phase 3 | An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia | September 12, 2023 | October 24, 2024 |
| NCT06387771 | Recruiting | Phase 2 | Evaluation of Tolcapone as a Cognitive Enhancer in Schizophrenia | September 22, 2014 | |
| NCT04324944 | Recruiting | N/A | Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness | July 5, 2022 | March 31, 2025 |
| NCT02853019 | Recruiting | N/A | Emotion and Motivation in Patients With Psychosis | February 2, 2017 | June 2025 |
| NCT04867681 | Recruiting | N/A | Study of the Impact on the Therapeutic Alliance of a Short Initial Psychoeducation Programme in Patients With Early Schizophrenia | December 8, 2021 | December 1, 2024 |
| NCT05646264 | Recruiting | Phase 4 | A Study on the Efficacy of Agomelatine Combined With Antipsychotics to Treat Negative Symptoms in Schizophrenia | January 1, 2023 | August 1, 2023 |
| NCT04436757 | Recruiting | N/A | Self and Body-esteem in Socio-professional Rehabilitation | June 22, 2020 | June 2023 |
| NCT05538832 | Recruiting | Early Phase 1 | Remote State Representation in Early Psychosis | July 27, 2022 | March 31, 2025 |
| NCT04959201 | Recruiting | Phase 2 | Combination of NMDA-enhancing and Antioxidant Treatments for Schizophrenia | November 30, 2020 | March 2025 |
| NCT04951700 | Recruiting | Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia | July 1, 2021 | April 30, 2027 | |
| NCT05837598 | Recruiting | N/A | Adapting the Tumor Board Model for Mental Illness and Cancer | May 31, 2023 | May 31, 2024 |
| NCT02647437 | Recruiting | N/A | Effects of Low-dose Levetiracetam on Clinical Symptoms, Cognition and Hippocampal Hyperactivity in Schizophrenia | June 2013 | June 2024 |
| NCT05516121 | Recruiting | Phase 1 | VLT-015 in Patients With Schizophrenia | February 1, 2021 | October 30, 2022 |
| NCT01980147 | Recruiting | N/A | Skills for Wellness | March 22, 2014 | June 30, 2024 |
| NCT05145413 | Recruiting | Phase 3 | A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia | November 12, 2021 | February 2025 |
| NCT06229210 | Recruiting | Phase 3 | Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia or Bipolar Disorder | January 25, 2024 | December 2027 |
| NCT06105151 | Recruiting | Phase 1 | Study of the Safety, Tolerability, Pharmacokinetics and Food Effects of VV119 Capsules in Chinese Healthy Volunteers | October 27, 2023 | December 2024 |
| NCT02878408 | Recruiting | N/A | Immuno-Genetic, Inflammation, Retro-Virus, Environment | November 2014 | November 2025 |
| NCT06389266 | Recruiting | N/A | Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia | June 15, 2023 | January 10, 2029 |
| NCT05413486 | Recruiting | Sleep, Obesity and Mental Disease - Biological Markers for the Evaluation of Circadian Rhythmicity | April 4, 2022 | July 31, 2024 | |
| NCT05890183 | Recruiting | N/A | Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode | May 23, 2023 | May 31, 2028 |
| NCT06123897 | Recruiting | Establishing a Clinical Database and Biobank for Schizophrenia：A Cohort Study | January 1, 2024 | December 31, 2028 | |
| NCT04968223 | Recruiting | Neural Correlates of Social Touch and Interoceptive Perception as Potential Biomarker for Impaired Social Functioning | August 16, 2021 | July 2024 | |
| NCT05480592 | Recruiting | Phase 1 | A Study of HS-10380 in Chinese Participants | August 1, 2022 | July 30, 2023 |
| NCT04946916 | Recruiting | N/A | Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease | October 22, 2021 | October 22, 2025 |
| NCT06071858 | Recruiting | N/A | Enhanced Coordinated Specialty Care for Early Psychosis | February 1, 2024 | October 2028 |
| NCT05206292 | Recruiting | N/A | Estimating Prevalence of Inherited Disorders of Sulfur Amino Acids Metabolism in Patients With Psychotic Disorders. | January 12, 2023 | June 1, 2025 |
| NCT05661448 | Recruiting | N/A | Promoting Cognitive Health in Schizophrenia | April 15, 2023 | August 31, 2029 |
| NCT05343598 | Recruiting | N/A | Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia | October 13, 2021 | October 31, 2026 |
| NCT06174116 | Recruiting | Phase 4 | Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia | April 2, 2024 | November 2026 |
| NCT04370730 | Recruiting | N/A | Dimensional and Developmental Profiles of Psychosis in Children and Adolescents | June 2, 2021 | October 1, 2026 |
| NCT05252039 | Recruiting | N/A | Goals in Focus: CBT for Motivational Negative Symptoms of Psychosis | March 1, 2020 | December 2024 |
| NCT00001246 | Recruiting | Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers | June 19, 1990 | ||
| NCT05278156 | Recruiting | Phase 2 | Efficacy, Safety and Pharmacokinetics Study of CPL500036 (PDE10A Inhibitor) in Patients With Schizophrenia | May 19, 2021 | July 2024 |
| NCT04025905 | Recruiting | N/A | Social Cognition Training and Vocational Rehabilitation | February 14, 2020 | June 15, 2025 |
| NCT03911726 | Recruiting | N/A | Do Antipsychotic Agents Induce Supersensitivity in Humans: A Combined PET/MRI Study in Patients With Schizophrenia | August 1, 2020 | December 31, 2024 |
| NCT04113993 | Recruiting | Phase 4 | Bazedoxifene -Treatment for Women With Schizophrenia | October 7, 2019 | December 31, 2025 |
| NCT05184335 | Recruiting | Phase 3 | Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia | January 24, 2022 | October 31, 2024 |
| NCT00001247 | Recruiting | Inpatient Evaluation of Adults With Schizophrenia | September 15, 1989 | ||
| NCT06061952 | Recruiting | N/A | CAE for Poorly Adherent Individuals With Schizophrenia | January 16, 2024 | April 30, 2025 |
| NCT02755623 | Recruiting | N/A | Structural and Functional Correlates of Clinical Response to rTMS Treatment in Schizophrenia Patients With Resistant Auditory Hallucinations | October 14, 2015 | October 8, 2025 |
| NCT05899348 | Recruiting | N/A | iTEST: Introspective Accuracy as a Novel Target for Functioning in Psychotic Disorders | October 1, 2023 | February 1, 2025 |
| NCT03495024 | Recruiting | Phase 4 | Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates | January 1, 2019 | June 30, 2020 |
| NCT06038955 | Recruiting | N/A | Effect of Immersive Virtual Reality-based Cognitive Remediation in Patients With Mood - or Psychosis Spectrum Disorders | October 1, 2022 | June 1, 2025 |
| NCT05830903 | Recruiting | N/A | Develop a Novel Occupational Training Program for Schizophrenia Patients Based on Virtual Reality Techniques | January 1, 2020 | December 31, 2023 |
| NCT05282186 | Recruiting | N/A | What the Nose Knows: Hedonic Capacity, Psychosocial Interventions and Outcomes in Schizophrenia | September 2, 2022 | February 28, 2025 |
| NCT00942981 | Recruiting | Functional Relevance of Dopamine Receptors in Healthy Controls and Patients With Schizophrenia: Characterization Through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography | November 13, 2009 | ||
| NCT06431009 | Recruiting | The Danish Region Midt Schizophrenia Cohort | February 20, 2024 | December 31, 2026 | |
| NCT06036108 | Recruiting | Phase 1 | Food Effect Study of Brexpiprazole Once-weekly (QW) Formulation in Patients With Schizophrenia | October 3, 2023 | January 2025 |
| NCT04267003 | Recruiting | N/A | Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia | January 9, 2020 | August 31, 2024 |
| NCT04395157 | Recruiting | Optimizing Cognitive Remediation | December 1, 2020 | April 30, 2025 | |
| NCT04300946 | Recruiting | Time Prediction and Cerebellum: Magnetic Transcranial Stimulation (TMS) in Healthy Volunteers | October 10, 2021 | October 1, 2023 | |
| NCT05545111 | Recruiting | Phase 2 | Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-1117568 in Adults With Schizophrenia | October 4, 2022 | December 2024 |
| NCT05957484 | Recruiting | N/A | The Effects of Non-invasive Neuromodulation on Illness Awareness in Schizophrenia | September 12, 2023 | September 15, 2026 |
| NCT05227703 | Recruiting | Phase 2 | A Trial of 15 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia | June 30, 2022 | December 2024 |
| NCT03708315 | Recruiting | Phase 2 | BXCL501 for Agitation in Schizophrenia | March 9, 2020 | June 2025 |
| NCT04783571 | Recruiting | N/A | Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia | April 13, 2020 | December 2024 |
| NCT05462340 | Recruiting | Phase 1 | PET Imaging Study of α7 and α4β2-nAChR in Schizophrenia | August 18, 2022 | May 31, 2024 |
| NCT05833009 | Recruiting | N/A | Acupuncture Treatment for Schizophrenia-related Central Obesity | October 1, 2022 | September 30, 2024 |
| NCT04001114 | Recruiting | N/A | Cigarette Smoking in Smokers With and Without Schizophrenia | July 15, 2021 | December 2023 |
| NCT06253546 | Recruiting | Phase 1 | Safety, Tolerability, and Pharmacokinetic Study of TV-44749 in Chinese Patients With Schizophrenia | March 28, 2024 | January 31, 2025 |
| NCT04610697 | Recruiting | N/A | Cognitive Remediation in Forensic Mental Health Care | February 10, 2020 | February 10, 2025 |
| NCT06278532 | Recruiting | Validation of the Lithuanian Version of the BNSS, CDSS, and the SCoRS | December 11, 2023 | December 11, 2026 | |
| NCT04518319 | Suspended | Phase 2 | Clinical Intervention on Cognitive Impairment of Schizophrenia With Metabolic Syndrome | October 1, 2020 | November 2024 |
| NCT02724917 | Suspended | Phase 1/Phase 2 | Safety, Tolerability, and Pharmacokinetics of APN1125 in Subjects With Schizophrenia | April 2016 | December 2016 |
| NCT02108899 | Suspended | N/A | Retrieval Practice and Schizophrenia | May 2014 | December 2022 |
| NCT00172497 | Suspended | Aggressive Acts Among Patients With Schizophrenia | August 2001 | October 2005 | |
| NCT05046353 | Suspended | Phase 1/Phase 2 | D-serine AudRem: R33 Phase | December 1, 2022 | August 31, 2025 |
| NCT03930225 | Suspended | N/A | Effectiveness of A Stigma Directed Interventional Program in Schizophrenia | April 16, 2019 | May 31, 2022 |
| NCT00197483 | Suspended | Effective Adjunctive Use of Pergolide for Cognitive Impairment and Negative Symptoms in Schizophrenia | March 2003 | ||
| NCT01908192 | Terminated | Phase 2/Phase 3 | Adaptive Phase II Study to Evaluate the Safety & Efficacy of NaBen® | June 2014 | October 26, 2023 |
| NCT00712075 | Terminated | N/A | Functional Rehabilitation for Older Patients With Schizophrenia | July 2008 | November 2010 |
| NCT00364429 | Terminated | Phase 1 | SPECT Investigation Of The NMDA Receptor System In Healthy Volunteers And Patients With Schizophrenia | July 2005 | July 2005 |
| NCT03588728 | Terminated | N/A | tDCS and Cognitive Training Intervention for Chronic Smokers With Schizophrenia | July 23, 2018 | March 12, 2020 |
| NCT01817387 | Terminated | N/A | Enhancing Motivation in Recent Onset Schizophrenia | July 2014 | March 20, 2018 |
| NCT01595503 | Terminated | N/A | Transcranial Magnetic Stimulation for the Treatment of Auditory Hallucinations in Schizophrenia | May 2011 | August 2012 |
| NCT01913327 | Terminated | Phase 4 | Antipsychotic Effects on Brain Function in Schizophrenia | April 2013 | January 2017 |
| NCT02614586 | Terminated | Phase 1 | Evaluation of TAK-058 and Ondansetron on P50 Auditory Gating in Participants With Stable Schizophrenia | December 2015 | April 2016 |
| NCT01764568 | Terminated | N/A | Contrasting Group Therapy Methods for Psychosis | January 2013 | June 2022 |
| NCT00857818 | Terminated | Phase 3 | Trial Comparing the Effects of Aripiprazole With Those of Standard of Care on Non-HDL Cholesterol in Patients With Schizophrenia or Bipolar I Disorder Who Have Metabolic Syndrome | April 2009 | March 2010 |
| NCT05961163 | Terminated | Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study | July 24, 2023 | September 3, 2023 | |
| NCT01465074 | Terminated | N/A | Effects of Acute Nicotine Treatment on Neuroplasticity and Memory in Patients With Schizophrenia | November 2011 | April 2013 |
| NCT03132571 | Terminated | Phase 2 | Naltrexone-Bupropion Versus Placebo-Bupropion for Weight Loss in Schizophrenia | June 1, 2017 | July 31, 2018 |
| NCT02572206 | Terminated | Phase 1 | PET Imaging Study of Amish and Mennonite Patients With CNTNAP2 Mutations | September 2015 | June 2016 |
| NCT00508157 | Terminated | Phase 4 | A Phase 4 Study to Assess the Effects of Aripiprazole Versus Other Atypical Antipsychotics in the Treatment of Schizophrenic Patients With Metabolic Syndrome | November 2007 | March 2009 |
| NCT03793712 | Terminated | Phase 2 | Study With Lu AF11167 for the Treatment of Negative Symptoms in Patients With Schizophrenia | December 27, 2018 | September 3, 2020 |
| NCT00206947 | Terminated | Phase 2 | The CAMPUS Project: Cholinergic Augmentation of Cognitive Deficits in Schizophrenia | December 2002 | January 2005 |
| NCT03929497 | Terminated | Phase 2 | Flexible-dose Long-term Extension Study of Lu AF11167 in Patients With Schizophrenia With Prominent Negative Symptoms | April 22, 2019 | September 14, 2020 |
| NCT02949232 | Terminated | Phase 4 | Prednisolone Addition for Patients With Recent-onset Psychotic Disorder | July 2014 | May 2019 |
| NCT00169039 | Terminated | Phase 4 | Clozapine Versus Chlorpromazine for Treatment-Unresponsive Schizophrenia | December 1994 | February 2002 |
| NCT03257592 | Terminated | Phase 1 | Positron Emission Tomography (PET) Imaging of Glial Activation in Psychotic Disease States | August 2010 | April 2018 |
| NCT02462473 | Terminated | Phase 2 | A Study to Assess the Clinical Utility of Antipsychotic Medication Levels in Plasma as Determined by Liquid Chromatography-Tandem Mass Spectrometry | May 2015 | January 2016 |
| NCT00547118 | Terminated | Phase 2 | The Effects of Rimonabant, on Weight and Metabolic Risk Factors | November 2007 | March 2009 |
| NCT00257192 | Terminated | Phase 3 | Safety And Efficacy Of Ziprasidone In Adolescents With Schizophrenia | April 2006 | March 2009 |
| NCT01328093 | Terminated | Phase 3 | A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients | April 2011 | October 2012 |
| NCT00457899 | Terminated | Phase 3 | Rapid Versus Conventional Titration of Quetiapine in Schizophrenia/Schizoaffective Disorder | July 2007 | September 2007 |
| NCT01832766 | Terminated | Phase 1/Phase 2 | The Effects of Cannabis Use in People With Schizophrenia on Clinical, Neuropsychological and Physiological Phenotypes | June 2005 | May 2011 |
| NCT02227563 | Terminated | N/A | tDCS & Auditory Hallucinations in Schizophrenia | March 2014 | August 2016 |
| NCT00288353 | Terminated | Phase 3 | Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes | January 2006 | December 2008 |
| NCT00044083 | Terminated | Phase 2 | Clinical Trial of Tolcapone for Cognition in Schizophrenia | August 2002 | December 2015 |
| NCT02764164 | Terminated | N/A | Transcranial Direct Current Stimulation (TDCS) for Auditory Hallucinations in Early Onset Schizophrenia (EOS) | January 2015 | August 2016 |
| NCT03892889 | Terminated | Phase 3 | A Trial in Adult Participants With Schizophrenia Treated Prospectively for 6-months With Abilify MyCite® | April 29, 2019 | September 29, 2020 |
| NCT01420575 | Terminated | N/A | Decision Aid to Facilitate Shared Decision Making During Treatment in Schizophrenia | October 2010 | August 2012 |
| NCT04548622 | Terminated | N/A | Bilateral Repetitive Transcranial Magnetic Stimulation for Auditory Hallucinations Results | September 2012 | October 2016 |
| NCT00511628 | Terminated | Study on the Safety of Risperidone on Obese or Overweight Patients With Schizophrenia | July 2001 | January 2003 | |
| NCT01368458 | Terminated | N/A | Conversion to Antipsychotic Monotherapy | December 2007 | July 2008 |
| NCT03900754 | Terminated | Phase 2 | A Pharmaco-imaging Approach to Predicting Social Functioning and Clinical Responses to Oxytocin Administration in Schizophrenia | January 13, 2020 | January 31, 2024 |
| NCT01244542 | Terminated | N/A | Pain and Schizophrenia | August 2011 | January 2015 |
| NCT03817528 | Terminated | Phase 2 | ITI-007 (Lumateperone Tosylate) for Schizophrenia | March 1, 2019 | September 23, 2020 |
| NCT01576640 | Terminated | Phase 4 | Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia | December 2005 | October 2007 |
| NCT01568216 | Terminated | Phase 2 | 20101299: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms | May 2012 | June 2013 |
| NCT02968121 | Terminated | Phase 1 | Safety and Tolerability Study of Single-dose Administration of Brexpiprazole in Adult Subjects With Schizophrenia | January 2017 | December 14, 2017 |
| NCT01077791 | Terminated | Phase 2 | A Study of a Remediation Program of Social Cognition in Schizophrenia | July 2008 | September 2010 |
| NCT01900522 | Terminated | Phase 1 | Safety and Tolerability of Multiple Doses of ITI-214 in Healthy Adults and in Adults With Stable Schizophrenia | July 2013 | December 2014 |
| NCT02374567 | Terminated | Phase 3 | Pharmacovigilance in Gerontopsychiatric Patients | January 2015 | June 28, 2017 |
| NCT00169091 | Terminated | Phase 4 | Clozapine Versus Haloperidol for Treating the First Episode of Schizophrenia | March 1996 | October 2003 |
| NCT00211562 | Terminated | Phase 3 | Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids | October 2005 | |
| NCT02796144 | Terminated | Phase 4 | MEtformin and Lorcaserin for WeighT Loss in Schizophrenia | September 2016 | February 14, 2020 |
| NCT01874756 | Terminated | Phase 2 | The Efficacy and Safety of a Selective Estrogen Receptor Beta Agonist (LY500307) for Negative Symptoms and Cognitive Impairment Associated With Schizophrenia | June 2013 | December 2017 |
| NCT00570063 | Terminated | Phase 2 | Double Blind, Randomized, 3 Week Inpatient Study To Evaluate The Safety & Efficacy Of PF-02545920 Compared With Placebo | November 2007 | February 18, 2008 |
| NCT03593213 | Terminated | Phase 3 | Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Participants With Schizophrenia | July 30, 2018 | February 11, 2021 |
| NCT00605995 | Terminated | N/A | Add-on Simvastatin in Schizophrenia Trial | February 2008 | August 2011 |
| NCT01738698 | Terminated | Phase 3 | Adjunctive SPD489 to Antipsychotic Medication in Clinically Stable Adults With Persistent Predominant Negative Symptoms of Schizophrenia | November 1, 2012 | April 1, 2013 |
| NCT01712646 | Terminated | Phase 1/Phase 2 | Daily Intranasal Oxytocin for Childhood-Onset Schizophrenia | October 5, 2012 | |
| NCT04421456 | Terminated | Phase 2 | Trial to Investigate the Safety and Efficacy of GWP42003-P Versus Placebo as Adjunctive Therapy in Participants With Schizophrenia Experiencing Inadequate Response to Ongoing Antipsychotic Treatment | August 18, 2020 | March 16, 2022 |
| NCT01454453 | Terminated | Phase 4 | Optimisation of Antipsychotic Drug Use in Older People | May 2012 | July 2015 |
| NCT00929370 | Terminated | Phase 1 | A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam. | July 2008 | March 2009 |
| NCT00314613 | Terminated | Phase 4 | Functional Brain Imaging and Employment in First-Episode Psychotic Patients Treated With Risperdal | April 2006 | |
| NCT00396214 | Terminated | Phase 3 | Compare the Effects of Bifeprunox and Quetiapine on Weight Changes in Stable Schizophrenic Patients | April 2007 | January 2008 |
| NCT01971073 | Terminated | N/A | Transcranial Direct Current Stimulation Influences on Cognitive Inhibition in Schizophrenia | January 2015 | March 7, 2018 |
| NCT02021201 | Terminated | Phase 4 | The Effect of Sertindole and Risperidone on Endophenotypic Markers of Schizophrenia | July 2008 | July 2013 |
| NCT00645515 | Terminated | Phase 3 | A Study Comparing the Safety and Efficacy of Ziprasidone and Risperidone for the Treatment of Chronic Schizophrenia | June 2003 | December 2003 |
| NCT03608137 | Terminated | N/A | Cannabis and Thought Disorder in Schizophrenia | December 7, 2018 | December 31, 2022 |
| NCT01943019 | Terminated | Phase 1 | Linagliptin in Schizophrenia Patients | August 2013 | August 2018 |
| NCT04203056 | Terminated | Phase 4 | Aripiprazole Lauroxil for Preventing Psychotic Relapse After an Initial Schizophrenia Episode | December 16, 2019 | October 1, 2022 |
| NCT04210557 | Terminated | N/A | Models of Auditory Hallucination | February 27, 2020 | April 1, 2021 |
| NCT00861497 | Terminated | Phase 3 | Bifeprunox Extension to Extension Study in Patients With Schizophrenia | January 2006 | July 2009 |
| NCT01615185 | Terminated | Phase 4 | A Randomized, Double-blind, Comparison of the Efficacy and Safety of Amisulpride Versus Low-dose Amisulpride Plus Low-dose Sulpiride in the Treatment of Schizophrenia | January 2008 | December 2011 |
| NCT00934635 | Terminated | Phase 4 | A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls | September 2009 | December 2009 |
| NCT00515489 | Terminated | Study on the Safety and Effectiveness of Risperidone Treatment of Acute Psychotic Patients | November 2001 | August 2002 | |
| NCT02715765 | Terminated | N/A | The Use of Transcranial Electrical Stimulation for Hallucinations | July 2016 | July 2016 |
| NCT00366704 | Terminated | Phase 3 | Study Comparing Bifeprunox to Risperidone in Treatment of Outpatients With Schizophrenia With Weight as Primary Endpoint | November 2006 | March 2008 |
| NCT01670071 | Terminated | Phase 4 | A Study to Evaluate the Effect of Oral Paliperidone Extended-Release and Oral Risperidone Immediate-Release on Cognitive Function in Clinically Stable Patients With Schizophrenia | January 2013 | June 2015 |
| NCT01177709 | Terminated | N/A | Metformin for Weight Loss in Schizophrenia | May 2008 | April 2011 |
| NCT00418873 | Terminated | Phase 4 | Zotepine Versus Risperidone in Aggressive Schizophrenic Patients of Acute Ward | March 2007 | December 2009 |
| NCT00314327 | Terminated | Phase 4 | Optimizing Response in Psychosis Study | April 2006 | November 2013 |
| NCT02234752 | Terminated | Phase 2 | Galantamine and Memantine Combination for Cognitive Impairments in Schizophrenia | September 2014 | July 2016 |
| NCT00155636 | Terminated | A Study on Etiological Factors of Schizophrenia | January 2002 | December 2005 | |
| NCT02746965 | Terminated | N/A | Magnetic Seizure Therapy for Schizophrenia | March 1, 2017 | July 30, 2018 |
| NCT02140788 | Terminated | Phase 4 | Effects of Metformin and Fish Oil on Treatment With Clozapine | May 2011 | February 2013 |
| NCT01592201 | Terminated | Phase 4 | A Comparative Study of Patient Satisfaction Between Continued Administration of Previous Antipsychotics Versus Switched Administration to Paliperidone ER in Non-satisfied Patients With Previous Antipsychotic Drug | July 2012 | June 2013 |
| NCT01654640 | Terminated | Phase 4 | The Effect of Metformin on Obesity and Metabolic Disturbance in Patients Taking Clozapine | September 2012 | April 2015 |
| NCT02717130 | Terminated | N/A | Aripiprazole, Abilify Maintena Collaborative Clinical Protocol | June 8, 2016 | May 25, 2017 |
| NCT00159757 | Terminated | Phase 4 | 12 Week Open, Non-Comparative Switch Study Of Oral Ziprazidone In Previously Treated Schizophrenic Patients | November 2003 | February 2005 |
| NCT00617214 | Terminated | Schizophrenic Patients Taking Part in Integrated Care Program | January 2008 | December 2008 | |
| NCT01760889 | Terminated | Phase 3 | SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia | February 1, 2013 | April 1, 2013 |
| NCT00757497 | Terminated | Phase 1 | Transcranial Direct Current Brain Stimulation to Treat Patients With Childhood-Onset Schizophrenia | September 17, 2008 | August 18, 2015 |
| NCT02261519 | Terminated | Phase 2/Phase 3 | Study to Evaluate Safety & Efficacy of NaBen® as Add-on Treatment for Schizophrenia in Adults | March 29, 2017 | November 29, 2023 |
| NCT04975035 | Terminated | Phase 1/Phase 2 | A Prospective, Open-ended, Multi-center Study of Schizophrenia Patients Switching to Zolodine | January 1, 2012 | July 1, 2012 |
| NCT00498004 | Terminated | Phase 4 | Quality of Life (QOL) in Female Patient With Schizophrenia | August 2007 | September 2008 |
| NCT00669903 | Terminated | Phase 2 | Study to Asses Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of AZD0328 in Patients With Schizophrenia | April 2008 | November 2008 |
| NCT03040505 | Terminated | Future Mental Projections in Schizophrenia | April 5, 2017 | October 20, 2019 | |
| NCT01192594 | Terminated | Phase 3 | Milestones of Adjustment Post-Psychosis | November 2009 | January 2013 |
| NCT00049738 | Terminated | Screening for Childhood-Onset Psychotic Disorders | October 29, 2002 | October 5, 2017 | |
| NCT00715377 | Terminated | N/A | Anticholinergic Burden in Schizophrenia | June 2007 | December 2011 |
| NCT01894984 | Terminated | An Observational Study to Evaluate Efficacy and Safety of Risperidone Long-Acting Injection for Treatment of Schizophrenia | January 2007 | December 2009 | |
| NCT00439634 | Terminated | Phase 2 | Efficacy and Safety of AVE1625 as a Co-treatment With Antipsychotic Therapy in Schizophrenia | February 2007 | September 2009 |
| NCT03261817 | Terminated | N/A | A Controlled Study With Remote Web-based Adapted Physical Activity (e-APA) in Psychotic Disorders | September 29, 2017 | June 22, 2021 |
| NCT00975611 | Terminated | Phase 4 | Study of Amantadine for Risperidone Consta or Paliperidone Treated Patients to Decrease Prolactin Elevation | October 2009 | January 2012 |
| NCT00931996 | Terminated | N/A | Oculomotor and Spatial Cognition Deficits in Schizophrenia | June 2009 | November 2011 |
| NCT02149823 | Terminated | Phase 1 | Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations | September 2013 | June 14, 2022 |
| NCT01137799 | Terminated | Phase 1 | The Effect of JNJ-39393406 on Event Related Potentials in Stable Schizophrenic Patients | August 2009 | March 2011 |
| NCT00211380 | Terminated | N/A | Cognitive Improvement With Aripiprazole (Abilify) in Patients With Schizophrenia (SFBRI) | August 2003 | February 2006 |
| NCT02512367 | Terminated | N/A | Evaluate the Efficacy of a Global Dental Health Promotion Program on Dental Hygiene in Patients With Schizophrenia. | April 20, 2017 | October 5, 2020 |
| NCT01929889 | Terminated | Phase 4 | Assessing the Effects of Fanapt® on Social Cognition in Schizophrenia | April 2012 | October 2014 |
| NCT03077347 | Terminated | N/A | The Effects of tDCS on the Neuronal Mechanisms of Cognitive Control in Schizophrenia | April 1, 2017 | February 23, 2023 |
| NCT01624831 | Terminated | Social Cognition in Longstanding Psychosis | November 2011 | November 2015 | |
| NCT01621737 | Terminated | N/A | Antipsychotic Effects of Oxytocin | June 2011 | December 2018 |
| NCT02144155 | Terminated | N/A | Open-label Study of the Efficacy of Intranasal Oxytocin in Schizophrenia | March 2012 | December 2014 |
| NCT03643159 | Terminated | Phase 4 | A Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite Versus Virtual Matched Controls in Adults With Schizophrenia, Bipolar 1 Disorder, and Major Depressive Disorder | June 28, 2018 | October 17, 2018 |
| NCT03637296 | Terminated | N/A | Adapting Critical Time Intervention to Support Inpatient Medical Care Transition | May 1, 2019 | December 31, 2020 |
| NCT00704509 | Terminated | Phase 3 | Efficacy of Bifeprunox in Patients With Schizophrenia | June 2008 | November 2009 |
| NCT05213143 | Terminated | Phase 4 | The Safety and Efficacy of Lurasidone In Subjects With Schizophrenia Switched From Olanzapine | December 30, 2021 | November 18, 2022 |
| NCT03602716 | Terminated | N/A | High-Definition Transcranial Direct Current Stimulation as a Treatment of Negative Symptoms of Schizophrenia | October 16, 2018 | September 26, 2020 |
| NCT03092687 | Terminated | Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core | March 21, 2017 | August 29, 2019 | |
| NCT02657941 | Terminated | N/A | Early and Short Psycho-educational Lifestyle Intervention | December 9, 2015 | November 14, 2017 |
| NCT00734435 | Terminated | Phase 2 | Olanzapine Given in Combination With Zonisamide SR to Prevent Weight Gain in Schizophrenic Subjects | September 2008 | December 2008 |
| NCT02983058 | Terminated | N/A | PET Imaging Study of Amish and Mennonite Patients With CNTNAP2 Mutations | November 2016 | July 2017 |
| NCT02242578 | Terminated | N/A | Treating Refractory Schizophrenia With rTMS | January 24, 2011 | June 11, 2018 |
| NCT00148590 | Terminated | Phase 3 | Memantine for the Prevention of Cognitive Dysfunction and Negative Symptoms in Patients With Acute Schizophrenia | November 2005 | December 2008 |
| NCT02739347 | Terminated | N/A | Non-Invasive Direct Current Stimulation for Cognition in Schizophrenia | May 2016 | June 2019 |
| NCT01139125 | Terminated | N/A | An Open Trial of Cysteamine Treatment in Schizophrenia | September 2009 | June 2012 |
| NCT03838484 | Terminated | N/A | Effects of Transdermal Nicotine on Response Inhibition to Emotional Cues in Schizophrenia | May 10, 2019 | February 24, 2020 |
| NCT00947375 | Terminated | Phase 4 | Lamictal TM, Haloperidol Decanoate in Schizophrenia | January 2005 | January 2007 |
| NCT00169026 | Terminated | Phase 4 | Alcoholism and Schizophrenia: Effects of Clozapine | May 1999 | January 2004 |
| NCT03896945 | Terminated | Phase 2/Phase 3 | Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Negative Symptoms of Schizophrenia | February 15, 2019 | May 23, 2023 |
| NCT00488891 | Terminated | The Paliperidone ER Observational Study of Economic, Functional, and Clinical Outcomes in Patients With Schizophrenia | April 2007 | October 2007 | |
| NCT01509053 | Terminated | Phase 3 | Open-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics Versus IM Depot Aripiprazole | January 2012 | October 2012 |
| NCT02131415 | Terminated | Real Life Assessment of Abilify Maintena | May 2014 | February 15, 2017 | |
| NCT00216281 | Terminated | Phase 3 | Efficacy and Safety Study of Clozapine Augmented by Atomoxetine Versus Clozapine Augmented by Placebo in Patients With Chronic Resistant Schizophrenia | September 2005 | September 2008 |
| NCT00486798 | Terminated | Phase 3 | FAST-A Study to Evaluate the Efficacy and Safety of Quetiapin IR in Patients With Acute Psychosis | May 2007 | August 2007 |
| NCT00232349 | Terminated | Phase 4 | Efficacy of Galantamine to Treat Schizophrenia | February 2005 | June 2007 |
| NCT00209027 | Terminated | N/A | The Effects of Aripiprazole on the Processing of Rewards in Schizophrenia | April 2005 | April 2011 |
| NCT01324297 | Terminated | The Topical Niacin Skin Flush Test in First Episode Psychosis | December 2011 | July 2016 | |
| NCT01307800 | Terminated | Phase 3 | A Study of LY2140023 in Patients With Schizophrenia | March 2011 | September 2012 |
| NCT02476708 | Terminated | N/A | A Pilot Trial of Curcumin Effects on Cognition in Schizophrenia | February 11, 2016 | August 24, 2017 |
| NCT01487083 | Terminated | Phase 3 | A Long-Term Study in Schizophrenia | December 2011 | October 2012 |
| NCT03852706 | Terminated | N/A | EEG-based Neurofeedback for Auditory Verbal Hallucinations (HALFEED) | March 1, 2019 | March 25, 2022 |
| NCT00517075 | Terminated | Phase 2 | Treatment of Negative Symptoms of Schizophrenia With Transcranial Magnetic Stimulation (TMS) | September 2004 | June 2011 |
| NCT00265382 | Terminated | Phase 3 | Safety And Tolerability Of Ziprasidone In Adolescents With Schizophrenia | June 2006 | June 2009 |
| NCT00001260 | Terminated | Brain Tissue Collection for Neuropathological Studies | May 29, 1990 | June 16, 2017 | |
| NCT01363349 | Terminated | Phase 2/Phase 3 | Phase IIb-III Study of BL-1020 Small Molecule for Schizophrenia | May 2011 | April 2013 |
| NCT01834638 | Terminated | Phase 2 | Long-term Safety and Efficacy of ABT-126 in Subjects With Schizophrenia: An Extension Study for Subjects Completing Study M10-855 (NCT01655680) | March 2013 | November 2014 |
| NCT00712270 | Terminated | Phase 4 | Best Event Schizophrenia Trial--A Randomized Double-Blind Trial of Aripiprazole and Risperidone in Schizophrenia | April 2005 | November 2010 |
| NCT01760993 | Terminated | Phase 3 | Long-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia | February 1, 2013 | April 1, 2013 |
| NCT00211302 | Terminated | N/A | Cognitive Improvement With Aripiprazole (Abilify) in Patients With Schizophrenia (BMS) | August 2003 | February 2006 |
| NCT00575848 | Terminated | Phase 1 | Study of the Effects of Glycine on Symptoms and Memory in Patients With Schizophrenia | December 2007 | October 2008 |
| NCT00001198 | Terminated | Evaluating Genetic Risk Factors for Childhood-Onset Schizophrenia | March 19, 1984 | October 10, 2017 | |
| NCT00366327 | Terminated | Phase 3 | Study Evaluating Bifeprunox in Patients With Schizophrenia. | January 2007 | March 2008 |
| NCT01063335 | Terminated | Imaging Cannabinoid CB1 Receptors in Schizophrenia | February 1, 2010 | September 20, 2012 | |
| NCT01125358 | Terminated | Phase 2 | A Study in Schizophrenic Patients | May 2010 | September 2012 |
| NCT02505022 | Terminated | Role Functioning Changes NOS | January 2016 | January 2021 | |
| NCT01568229 | Terminated | Phase 2 | 20110165: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms (Study 165) | May 2012 | August 2013 |
| NCT00591318 | Terminated | Phase 1/Phase 2 | A Placebo-controlled Efficacy Study of IV Ceftriaxone for Refractory Psychosis | October 10, 2007 | March 17, 2011 |
| NCT00681629 | Terminated | Phase 4 | Schizophrenic Patients in Integrated Care | July 2008 | November 2008 |
| NCT01851603 | Terminated | Phase 1 | Phase I Study to Evaluate the Safety and Pharmacokinetics of Oral Doses of Anvylic-3288 in Healthy Subjects | June 2013 | August 2016 |
| NCT04742413 | Terminated | A 12-Month Observational Prospective Cohort Study to Analyze Cardiometabolic Profile Changes to Switch to Lurasidone in Patients With Schizophrenia. RESPECT Study. | December 29, 2020 | March 15, 2022 | |
| NCT00184509 | Terminated | Phase 3 | Continued Early Intervention for Recent-onset Schizophrenia | February 1993 | May 1998 |
| NCT03318640 | Terminated | N/A | Mindfulness and Cognition in Schizophrenia | September 11, 2018 | July 12, 2021 |
| NCT00852631 | Terminated | Phase 3 | Seroquel XR in Adults With Schizophrenia | February 2009 | May 2010 |
| NCT04825860 | Terminated | Phase 2/Phase 3 | A Clinical Trial to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic People With Schizophrenia, Followed by an Open-label Extension Phase | March 29, 2021 | October 19, 2023 |
| NCT01939548 | Terminated | Phase 2 | An Outpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Adjunctive Treatment Of Sub-Optimally Controlled Symptoms of Schizophrenia | October 2013 | October 2014 |
| NCT02435095 | Terminated | Phase 4 | Antipsychotic Induced Structural and Functional Brain Changes | May 2015 | August 2020 |
| NCT05359081 | Terminated | Phase 3 | A Clinical Trial to Evaluate the Long-term Safety and Tolerability of SEP-363856 in Patients With Schizophrenia in Japan | May 16, 2022 | March 28, 2024 |
| NCT03868839 | Terminated | Phase 2 | Telmisartan Pilot Study on Treatment Resistant Schizophrenia | February 1, 2019 | October 7, 2020 |
| NCT02383095 | Terminated | N/A | Efficiency of Art-therapy in Psychotic Disorders | May 27, 2015 | October 2019 |
| NCT00885690 | Terminated | N/A | Comparing the Effects of Sertindole and Olanzapine on Cognition (SEROLA) | April 2009 | November 2012 |
| NCT00256997 | Terminated | Phase 4 | A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Participants With a History of Being Poorly Compliant With Taking Their Medication | January 2006 | April 2009 |
| NCT03351244 | Terminated | Phase 2 | This Study Tests Whether BI 409306 Prevents Patients With Schizophrenia From Becoming Worse. This Study Looks at How Well Patients Tolerate BI 409306 and How Effective it is Over 6 Months | December 7, 2017 | March 31, 2021 |
| NCT01129674 | Terminated | Phase 2/Phase 3 | A Long-Term, Open-Label, Study on Schizophrenia | June 2010 | October 2012 |
| NCT00645229 | Terminated | Phase 3 | A Study of the Efficacy and Safety of Ziprasidone in Patients With Acute Exacerbation of Schizophrenia or Schizoaffective Disorder | September 2004 | March 2005 |
| NCT01011101 | Terminated | Internal Monitoring of Eye Movement in Schizophrenia | November 2, 2009 | August 16, 2016 | |
| NCT03220438 | Terminated | N/A | TMS Enhancement of Visual Plasticity in Schizophrenia | September 27, 2017 | July 16, 2019 |
| NCT00977522 | Terminated | Phase 2 | A Study Of PF-03463275 As Add-On Therapy In Outpatients With Persistent Negative Symptoms Of Schizophrenia | November 2009 | September 2010 |
| NCT00701753 | Terminated | A Pharmacogenetic Investigation of Antipsychotics in Schizophrenia and Schizophrenia-Like Psychoses | May 2008 | March 2009 | |
| NCT03544333 | Terminated | N/A | Boost rTMS for Auditory Verbal Hallucinations | April 16, 2018 | January 22, 2019 |
| NCT02435836 | Terminated | Phase 3 | A Follow-on Study of the Long-Term Safety of Aripiprazole in Patients With Chronic Schizophrenia | April 1998 | December 2012 |
| NCT00629252 | Terminated | N/A | The Effect of Sertindole on Sensory Gating and Cognition in Schizophrenic Patients | February 2008 | August 2012 |
| NCT04109950 | Terminated | Phase 3 | A Clinical Study to Evaluate the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia | October 4, 2019 | November 9, 2023 |
| NCT01491490 | Terminated | Phase 2 | Treatment on Iatrogenic Weight Gain and Dyslipidaemia Associated With Olanzapine | October 2011 | October 2012 |
| NCT05643170 | Terminated | Phase 3 | An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia | November 8, 2022 | March 8, 2023 |
| NCT05654870 | Terminated | Phase 3 | Study to Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as an Adjunctive Treatment for Schizophrenia | January 5, 2023 | November 8, 2023 |
| NCT04033978 | Terminated | N/A | Cerebral Impact of Cognitive Remediation for People Suffering From Schizophrenia | December 17, 2019 | June 17, 2023 |
| NCT00658645 | Terminated | Phase 3 | Efficacy of Bifeprunox in Patients With Schizophrenia | March 2008 | November 2009 |
| NCT00419653 | Terminated | Phase 4 | Modulation of Regional Brain Activation in Schizophrenic Patients by Pharmacological Therapy | January 2003 | September 2007 |
| NCT00946985 | Terminated | Phase 4 | 28-30 Month Study Comparing Paliperidone Palmitate With Oral Risperidone for Treating Adults Diagnosed With Schizophrenia Within the Past 5 Years | June 2009 | March 2010 |
| NCT01071135 | Terminated | Phase 3 | Quetiapine XR in Schizophrenic Patients | September 2009 | August 2010 |
| NCT01568203 | Terminated | Phase 1 | First-in-Human Study to Evaluate AMG 579 in Healthy Subjects and Patients With Stable Schizophrenia | September 2011 | June 2012 |
| NCT00548327 | Terminated | Phase 2 | The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype | October 2007 | November 2011 |
| NCT00412620 | Terminated | Phase 2 | An Evaluation of the Safety and Efficacy of ABT-925 in Subjects With Acute Exacerbation of Schizophrenia | December 2006 | October 2007 |
| NCT00998608 | Terminated | Phase 4 | Comparison of the Efficacy and Safety of Risperidone Versus Risperidone Plus Low Dose of Haloperidol in the Treatment of Schizophrenia | August 2007 | October 2009 |
| NCT01813955 | Terminated | Early Phase 1 | Phosphodiesterase (PDE) Inhibitors Effect on Cognitive Deficits Associated to Schizophrenia | June 2011 | June 2013 |
| NCT00506909 | Terminated | N/A | Oxytocin Add on Study for Stable Schizophrenic Patients | March 2008 | March 2014 |
| NCT03209778 | Terminated | N/A | Involuntary Memories Investigation in Schizophrenia | September 29, 2017 | December 15, 2019 |
| NCT04533724 | Unknown status | Early Phase 1 | Study on the Gut Microbial Mechanism of Negative Symptoms of Schizophrenia | October 1, 2020 | September 30, 2022 |
| NCT01078870 | Unknown status | Phase 4 | Trial for Antidepressant Treatment for Negative Symptom of Schizophrenia With NRG1 Risk Genotype | February 2010 | January 2011 |
| NCT05159336 | Unknown status | N/A | Transcranial Alternating Current Stimulation (tACS) for Auditory Hallucinations | November 16, 2021 | May 28, 2023 |
| NCT04124744 | Unknown status | N/A | A Pilot Randomised Controlled Trial of a Health Champion Intervention | April 2, 2020 | May 30, 2022 |
| NCT02823639 | Unknown status | N/A | Efficacy and Mechanisms of Transcranial Direct Current Stimulation (tDCS) - Effects on Working Memory in Schizophrenia | October 2015 | October 2022 |
| NCT04446234 | Unknown status | Phase 4 | Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building | May 2021 | December 31, 2022 |
| NCT02841345 | Unknown status | N/A | Characterization of Emotional Processing of Information in Bipolar Disorder and Schizophrenic Patients | December 2011 | February 29, 2020 |
| NCT03481465 | Unknown status | Searching for Early Biomarkers of Long-term Hepatic, Metabolic and Endothelial Dysfunction in Non-affective Psychosis | February 12, 2018 | December 2020 | |
| NCT02842034 | Unknown status | N/A | Repetitive Transcranial Magnetic Stimulation for the Treatment of Negative Symptoms in Schizophrenia Patients. | July 2016 | December 2018 |
| NCT02627716 | Unknown status | N/A | Joint Crisis Plan Effectiveness in Preventing Relapses in Schizophrenia and Schizoaffective Disorder | December 2014 | July 2022 |
| NCT02110017 | Unknown status | N/A | Exploration of Neural Bases in Social Cognition | September 2013 | September 2015 |
| NCT03972735 | Unknown status | N/A | Assessment of the Effectiveness of the NECT Program | February 10, 2020 | April 1, 2023 |
| NCT03369795 | Unknown status | Phase 2 | Add-on Methotrexate for the Treatment of Schizophrenia | December 15, 2017 | January 1, 2020 |
| NCT00645580 | Unknown status | N/A | Genetic Expression in Schizophrenics Treated With SSRI Augmentation: Relationship to Clinical and Cognitive Function | April 2008 | April 2009 |
| NCT03240380 | Unknown status | N/A | Joint Crisis Plans or Crisis Cards for People With Severe Mental Disorders to Reduce Coercion in Psychiatric Care. | May 1, 2017 | June 30, 2019 |
| NCT04276012 | Unknown status | N/A | Effectiveness of a Cardiovascular Risk Intervention Program in Patients With Schizophrenia (PRISCA) | January 20, 2020 | February 28, 2021 |
| NCT03007303 | Unknown status | The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients | June 2016 | July 2020 | |
| NCT01561742 | Unknown status | N/A | Minocycline Augmentation in Schizophrenia | February 2012 | January 2015 |
| NCT02159001 | Unknown status | N/A | Electroconvulsive Therapy in Clozapine-resistant Schizophrenia | June 2014 | June 2018 |
| NCT02529163 | Unknown status | N/A | Evaluating the Efficacy of a Late-Life Schizophrenia Integrated Care Pathway to Treat Acute Psychotic Symptoms | August 2015 | July 2019 |
| NCT01315587 | Unknown status | Phase 2 | Repetitive Transcranial Magnetic Stimulation and Intermittent Theta Burst (iTBS) in Schizophrenia | January 2011 | January 2017 |
| NCT04399096 | Unknown status | Sound and Vision: A Collaboration Between Service-users, Artists and the Public to Explore the Lived Experience of Hallucinations | December 1, 2020 | December 2021 | |
| NCT03414151 | Unknown status | Gut Microbiome in AP Naive | February 7, 2018 | March 2022 | |
| NCT00564096 | Unknown status | Phase 2/Phase 3 | Transcranial Magnetic Stimulation (TMS) in Schizophrenia | October 2008 | December 2011 |
| NCT00300651 | Unknown status | Phase 3 | Trial of Cognitive Behavioral Therapy for Schizophrenia | March 2006 | August 2009 |
| NCT03862209 | Unknown status | N/A | Community-based Mental Health Care for People With Severe and Enduring Mental Ill Health (RECOVER-E) Croatia | January 1, 2018 | July 1, 2021 |
| NCT04481217 | Unknown status | N/A | Cognitive Factors Mediating the Relationship Between Childhood Trauma and Auditory Hallucinations in Schizophrenia | September 4, 2020 | July 2023 |
| NCT00330226 | Unknown status | Efficacy and Safety of Psychopharmacotherapy in Patients With Schizophrenia or Bipolar Disorders | January 2006 | December 2012 | |
| NCT00395915 | Unknown status | Phase 4 | Randomized Evaluation of the Effectiveness of Clozapine and Aripiprazole Versus Clozapine and Haloperidol in the Treatment of Schizophrenia | September 2006 | December 2009 |
| NCT02591498 | Unknown status | Phase 3 | Computerized Cognitive Training for Schizophrenia in Brazil | January 2014 | December 2019 |
| NCT02552758 | Unknown status | N/A | The Influence of Omega-3 Fatty Acid on the Violence of Schizophrenia Patient and the Possible Mechanism | May 2015 | December 2016 |
| NCT00352339 | Unknown status | Phase 4 | The New Strategy for Pharmacological Treatment in People With Schizophrenia | August 2006 | December 2010 |
| NCT03302364 | Unknown status | A Research in Pharmacogenomics and Accurate Medication of Risperidone | October 22, 2017 | June 2020 | |
| NCT02986490 | Unknown status | N/A | Magnesium Variations and Cardiometabolic Risk in Patients With Antipsychotic Drugs | September 2014 | December 2017 |
| NCT05068765 | Unknown status | N/A | The Effect of the Psychoeducation Program on the Subjective Well-being of Caregivers | October 1, 2021 | December 30, 2022 |
| NCT02366117 | Unknown status | N/A | Rehabilitation and Quality of Life in Residential Units for People With Longer Term Mental Health Problems | April 2012 | February 2015 |
| NCT03881449 | Unknown status | Phase 4 | DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole | April 4, 2019 | November 2021 |
| NCT03080194 | Unknown status | Phase 4 | The Effect of a Community-based LAI-treated Management Model on the Violence Risk of Patients With Schizophrenia | April 2017 | April 2018 |
| NCT02652832 | Unknown status | N/A | Effects of Noninvasive Brain Stimulation Techniques on BDNF Levels | December 2010 | June 30, 2019 |
| NCT03223844 | Unknown status | N/A | Influence of Amphetamine-induced Sensitization on Dopamine Synthesis and Release | January 1, 2018 | December 2021 |
| NCT02423096 | Unknown status | Neuroendocrine and Metabolite Substrates in Schizophrenia | December 2013 | December 2016 | |
| NCT04177719 | Unknown status | N/A | Neurobiological Effects of Oxytocin in Schizophrenia | November 8, 2019 | April 2022 |
| NCT03922425 | Unknown status | N/A | Community-based Mental Health Care for People With Severe and Enduring Mental III Health | January 1, 2018 | June 1, 2022 |
| NCT00278668 | Unknown status | ECT Schizophrenia Serotonin Study | October 2006 | October 2006 | |
| NCT03510325 | Unknown status | Phase 4 | Chinese First Episode Schizophrenia's Optimal Dynamic Antipsychotic Treatment Regime | October 1, 2018 | September 1, 2021 |
| NCT03790085 | Unknown status | Early Phase 1 | Identification of Multi-modal Bio-markers for Early Diagnosis and Treatment Prediction in Schizophrenia Individuals | September 1, 2018 | December 31, 2020 |
| NCT01490567 | Unknown status | Phase 4 | A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia | June 2011 | June 2012 |
| NCT01689181 | Unknown status | Apathy in Schizophrenia | June 2012 | September 2013 | |
| NCT03995420 | Unknown status | N/A | VR Therapy for Psychosis Negative Symptoms (V-NeST) | October 15, 2019 | April 30, 2021 |
| NCT02200588 | Unknown status | Longitudinal Long-term Study (10 Years) of the Sample of First Episode of Non-affective Psychosis: PAFIP | September 2014 | December 2020 | |
| NCT02453893 | Unknown status | Phase 3 | Risperidone-controlled,Multicentre Clinical Trial of Iloperidone in Patients With Schizophrenia | November 2013 | |
| NCT01045824 | Unknown status | Family-based Genetic Long-term Study of Brain Function in Schizophrenia | January 2008 | January 2014 | |
| NCT04562961 | Unknown status | N/A | Diagnostic Announcement to Relatives of Patients With Schizophrenia | October 10, 2020 | April 10, 2021 |
| NCT03261557 | Unknown status | N/A | Cognitive Behavioral Social Skills Training in Early Onset Psychosis | February 22, 2017 | September 2020 |
| NCT03469089 | Unknown status | Phase 1 | Touchscreen-based Cognitive Tests in Healthy Volunteers | March 12, 2018 | December 31, 2019 |
| NCT05243160 | Unknown status | N/A | Medication Review in Patients With Schizophrenia and Diabetes | February 11, 2022 | October 1, 2022 |
| NCT03708549 | Unknown status | Phase 4 | Comparison of Berberine and Metformin for the Treatment for MS in Schizophrenia Patients | December 1, 2021 | December 1, 2023 |
| NCT01324167 | Unknown status | Effects of Gene Polymorphisms on Metabolic Features in Clozapine-treated Patients With Schizophrenia | May 2010 | April 2011 | |
| NCT04237155 | Unknown status | N/A | French Source-monitoring Task | February 7, 2020 | February 1, 2024 |
| NCT02834208 | Unknown status | N/A | Emotion Endophenotypes in Schizophrenia | December 2015 | June 2019 |
| NCT00173329 | Unknown status | The Quality of Life of Patients With Severe Illnesses | August 2005 | July 2006 | |
| NCT00894296 | Unknown status | Magnetoencephalographic (MEG) Correlates of Negative Symptoms in Patients Suffering From Schizophrenia and Their Influence by Add-on Treatments | March 2009 | January 2013 | |
| NCT01182012 | Unknown status | Phase 4 | Reduction of Cardiovascular Risk in Severe Mental Illness | August 2010 | December 2012 |
| NCT00619437 | Unknown status | Genetics of Schizophrenia | April 2008 | December 2009 | |
| NCT00392249 | Unknown status | Phase 1/Phase 2 | Supervised Treatment of Schizophrenia, a Randomized Controlled Trial. | November 2006 | September 2008 |
| NCT04907279 | Unknown status | Aripiprazole Once-Monthly in Hospitalized Patients (INITIATE) | November 1, 2021 | June 2023 | |
| NCT01357005 | Unknown status | Expanding Rapid Ascertainment Networks of Schizophrenia Families in Taiwan | October 2010 | ||
| NCT00225602 | Unknown status | N/A | Assertive Community Treatment in Copenhagen | January 2004 | May 2006 |
| NCT02884518 | Unknown status | N/A | Predicting Antipsychotic Discontinuation in Psychosis | October 4, 2016 | December 2019 |
| NCT02378818 | Unknown status | N/A | Characterization of the Motivational Deficit in Schizophrenia and Depression | November 21, 2014 | January 2019 |
| NCT01792856 | Unknown status | N/A | Coaching Intervention for Patients With Early Psychosis | February 2013 | August 2015 |
| NCT05039489 | Unknown status | N/A | A Study on the Brain Mechanism of cTBS in Improving Medication-resistant Auditory Hallucinations in Schizophrenia | September 9, 2021 | November 30, 2023 |
| NCT01546467 | Unknown status | N/A | Cognitive Remediation in Early Phase Psychosis | September 2009 | December 2013 |
| NCT02884739 | Unknown status | Mental Healthcare in Older Adults With Schizophrenia | January 2010 | July 2018 | |
| NCT00111202 | Unknown status | Schizophrenia and Genetic Counseling | May 2005 | June 2006 | |
| NCT00138021 | Unknown status | N/A | Cognitive Remediation in Supported Employment at Human Service Center (HSC) | July 2005 | May 2008 |
| NCT00409201 | Unknown status | Phase 1 | Reboxetine Adjuvant Therapy for the Treatment of Schizophrenia | March 2006 | November 2006 |
| NCT03192631 | Unknown status | N/A | Financial Incentives to Improve Acceptance of Antipsychotic Injections | July 1, 2017 | December 31, 2021 |
| NCT02942459 | Unknown status | N/A | Music Therapy Towards Schizophrenia, Negative Symptoms | September 1, 2015 | December 31, 2020 |
| NCT03005574 | Unknown status | N/A | Comparing Thinking Skills for Work (TSW)Home Practice Program With Traditional TSW Program | January 2017 | December 2020 |
| NCT01903915 | Unknown status | Social Dysfunction and Brain Dysfunction in Patients With Schizophrenia | July 2012 | April 2015 | |
| NCT05301660 | Unknown status | Early Phase 1 | Effect of Nicotine Transdermal Patch on Cognitive Function and Glycolipid Metabolism in Non-smoking Schizophrenia | March 22, 2022 | February 15, 2023 |
| NCT02932059 | Unknown status | N/A | Evaluation of Metamemory Using a Semantic Construction Strategy in Patients With Schizophrenia | June 19, 2017 | September 2020 |
| NCT01249079 | Unknown status | Expanding Rapid Ascertainment Network of Schizophrenia Families in Taiwan | October 2010 | ||
| NCT02850445 | Unknown status | N/A | Trial and Follow-up of the Efficacy of Two-stage Integrated Treatment for Chinese Schizophrenia Inpatients | January 2012 | |
| NCT00006195 | Unknown status | N/A | Glucose Regulation During Risperidone and Olanzapine Treatment | ||
| NCT02426983 | Unknown status | Phase 1/Phase 2 | Pilot Study Using an NMDA Antagonist to Modulate Transcranial Direct Current Stimulation (tDCS) Effects on Sensory Discrimination | April 2015 | April 2016 |
| NCT01259232 | Unknown status | The Imaging Genetic Study of Schizophrenia and Family | September 2011 | December 2022 | |
| NCT01280305 | Unknown status | Phase 3 | Raloxifene in Treatment of Schizophrenia and Schizoaffective Disorder | March 2011 | March 2013 |
| NCT02210962 | Unknown status | Phase 4 | Omega-3 Fatty Acids Efficacy in First-episode of Schizophrenia | September 2011 | February 2015 |
| NCT00192582 | Unknown status | N/A | AIMHI NT Relapse Prevention Trial | July 2005 | August 2007 |
| NCT01047215 | Unknown status | Phase 4 | Heart Rate Changes in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine | August 2009 | June 2010 |
| NCT03090490 | Unknown status | N/A | 10-year Follow-up of Clinical Outcome After Antipsychotic Treatment Discontinuation in Psychosis Individuals | September 2014 | December 2020 |
| NCT02095938 | Unknown status | Phase 4 | Association of Amisulpride Response in Schizophrenia With Brain Image | January 2014 | December 2015 |
| NCT04430309 | Unknown status | N/A | Baduanjin on Patients With Schizophrenia | April 10, 2021 | June 30, 2022 |
| NCT04551027 | Unknown status | N/A | Assessing the Effect of Compensatory Cognitive Intervention Among People With Severe Mental Illness | September 2020 | December 2021 |
| NCT00315081 | Unknown status | Phase 3 | Risperidone-Induced Hyperprolactinemia Treated With Bromocriptine | May 2006 | May 2008 |
| NCT01057849 | Unknown status | N/A | Standard Comprehensive Intervention to Treat First-episode Schizophrenia | September 2008 | |
| NCT02681822 | Unknown status | Multi-center Imaging Genetics Studies in China | November 2015 | December 2020 | |
| NCT00469664 | Unknown status | Phase 4 | Guanfacine Adjunctive Treatment to Atypical Antipsychotics for Cognitive Dysfunction in Schizophrenia | February 2000 | December 2008 |
| NCT01858857 | Unknown status | Geriatric Psychiatry and Pharmacovigilance | May 2013 | December 2015 | |
| NCT04143308 | Unknown status | N/A | The Effects of Simultaneous Training of Walking and Cognitive Tasks on Cognitive Functions of People With Schizophrenia | November 5, 2019 | July 31, 2021 |
| NCT04520399 | Unknown status | Prediction of Violent Behavior in Patients With Schizophrenia by Multimodal Machine Learning | October 2020 | September 2022 | |
| NCT02127879 | Unknown status | N/A | Intensive Transcranial Magnetic Stimulation for Negative Symptoms in Schizophrenia | May 2014 | October 2016 |
| NCT03892473 | Unknown status | N/A | Community-based Mental Health Care for People With Severe and Enduring Mental III Health ( RECOVER-E ) | January 1, 2018 | June 1, 2022 |
| NCT03973853 | Unknown status | N/A | How Can a Driving Virtual Reality Tool Improve Quality of Life and Social Autonomy in Patients With Schizophrenia | June 25, 2019 | June 2023 |
| NCT02622048 | Unknown status | N/A | Understanding and Helping Families: Parents With Psychosis | September 2015 | July 2017 |
| NCT00215917 | Unknown status | Phase 1/Phase 2 | D-Serine Monotherapy for Schizophrenia | ||
| NCT05345548 | Unknown status | N/A | Sensitivity, Threshold, Tolerance and Pain Recognition in Schizophrenia Patients and Their Relatives. | August 29, 2019 | January 15, 2024 |
| NCT00685321 | Unknown status | N/A | Tolerability, Safety and Efficacy of the H1-coil Deep Transcranial Magnetic Stimulation in Subjects With Negative Symptoms and Cognitive Deficits of Schizophrenia | June 2008 | January 2013 |
| NCT01045720 | Unknown status | Phase 2 | The Treatment of 2 Chinese Medicines in Clozapine-induced Hypersalivation in Schizophrenia | January 2010 | March 2010 |
| NCT00789906 | Unknown status | Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia | July 2008 | ||
| NCT02826629 | Unknown status | N/A | "Manual Dexterity and Oculomotor Control in Schizophrenia" | July 26, 2016 | January 2019 |
| NCT00717509 | Unknown status | Association of Multiple Genetic Polymorphisms With Clozapine-Associated Metabolic Change in Schizophrenia | October 2007 | October 2009 | |
| NCT02093858 | Unknown status | The Mechanism of TCF7L2 and SLC30A8 on Antipsychotic-induced Metabolic Syndrome | April 2014 | December 2017 | |
| NCT05339347 | Unknown status | Phase 2 | Schizophrenia Treatment With Photoneuromodulation | August 1, 2021 | September 30, 2022 |
| NCT04430868 | Unknown status | N/A | Lifestyle Redesign For Schizophrenia | July 1, 2020 | November 30, 2020 |
| NCT01474395 | Unknown status | Phase 2 | N-methyl-D-aspartic Acid (NMDA) and Cognitive Remediation in Schizophrenia | March 2012 | June 2013 |
| NCT03552237 | Unknown status | N/A | Effect of Dietary Fiber Supplement on the Intestinal Microbiota Among Schizophrenia Patients | June 20, 2018 | December 30, 2018 |
| NCT03576911 | Unknown status | N/A | A Randomised Controlled Trial of Coenzyme Q10 in Patients With Schizophrenia and Schizoaffective Disorder | November 2016 | August 2019 |
| NCT00789022 | Unknown status | Glutamatergic Amino Acids and Oxytocin Levels in the Plasma of Patients in First Psychotic Episode (FPE)- Before and After Neuroleptic Treatment | January 2009 | ||
| NCT00435721 | Unknown status | Phase 1 | Families Coping With Mental Illness Program | June 2002 | August 2005 |
| NCT02746510 | Unknown status | N/A | Validation of a Clinical Screening Grid for Syndromic Schizophrenia | July 2016 | December 2023 |
| NCT00885716 | Unknown status | N/A | A Shared Decision Making Training for Inpatients With Schizophrenia | May 2009 | |
| NCT01769014 | Unknown status | Adherence and Quality of Life in People With Schizophrenia and Schizoaffective Disorder | January 2013 | December 2013 | |
| NCT03146364 | Unknown status | N/A | Evaluation of Executive Function With Virtual Reality Among People With Schizophrenia | July 1, 2017 | August 1, 2018 |
| NCT02588014 | Unknown status | The Neural Bases of Early Visual and Auditory Processing and Emotion Recognition Deficits in Schizophrenia | November 2015 | December 2019 | |
| NCT00166738 | Unknown status | Analysis of Genomic DNA Alterations in Familial Schizophrenia | September 2005 | December 2005 | |
| NCT03790345 | Unknown status | Phase 2/Phase 3 | Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics | September 3, 2019 | November 3, 2021 |
| NCT04144075 | Unknown status | N/A | Application of a Mindfulness and Self-Compassion Program in Patients With Schizophrenia. Randomized Controlled Trial. | May 1, 2020 | February 15, 2021 |
| NCT03163706 | Unknown status | N/A | Evaluation of Stroop Effect in Patients With Schizophrenia | September 21, 2016 | June 2019 |
| NCT00646256 | Unknown status | N/A | Cognitive Determinants of Psychoeducation and Information in Psychoses | February 2006 | |
| NCT03284294 | Unknown status | Phase 3 | Influence of Vitamin D Supplementation on Serum BDNF Level and Cognitive Function in Schizophrenia | April 15, 2020 | December 2020 |
| NCT03117452 | Unknown status | N/A | Evaluation of a Visual Remediation Intervention for Schizophrenia | February 23, 2017 | February 28, 2019 |
| NCT00569764 | Unknown status | Effect on Metabolic Parameters of Abilify in SPR | December 2007 | October 2009 | |
| NCT02511509 | Unknown status | N/A | Bifrontal and Bitemporal Electroconvulsive Therapy (ECT) in Treatment of Patients With Schizophrenia | September 2015 | July 2019 |
| NCT05208021 | Unknown status | N/A | The Effect of Psychoeducation Program on Healthy Living Behaviors | March 29, 2021 | April 2022 |
| NCT01389908 | Unknown status | N/A | A Follow up Study of Intramuscular Olanzapine Depot in Patients With Schizophrenia or Schizoaffective Disorder | June 2011 | |
| NCT04147897 | Unknown status | N/A | Implementing mHealth for Schizophrenia in Community Mental Health Settings | June 16, 2020 | April 1, 2024 |
| NCT02040883 | Unknown status | Phase 4 | Tandospirone Combined With Atypical Antipsychotic Drugs in Schizophrenia | February 2014 | December 2014 |
| NCT02282085 | Unknown status | Phase 4 | Treatment Study Comparing Aripiprazole Once Monthly With Standard of Care Medication in Outpatients With Schizophrenia | December 2014 | |
| NCT00204087 | Unknown status | Phase 3 | Psychological Intervention for Persons in the Early Initial Prodromal State | January 2001 | June 2005 |
| NCT00788970 | Unknown status | N/A | Shiatsu Adjuvant Therapy And Placebo For Schizophrenia | January 2009 | December 2011 |
| NCT02916303 | Unknown status | Cost-effectiveness of Interventions in First-episode Psychosis | June 2016 | December 2020 | |
| NCT01133080 | Unknown status | Phase 4 | Minocycline as an Adjunctive Therapy for Schizophrenia: a Randomized Controlled Study | June 2010 | January 2013 |
| NCT04335916 | Unknown status | Survey on Pre-ECT Evaluation and ECT Application | April 1, 2020 | November 1, 2020 | |
| NCT03829124 | Unknown status | Phase 4 | Comparison of Ketamine Combine Propofol vs Propofol Anesthesia in Schizophrenia Electroconvulsive Therapy | May 24, 2019 | April 20, 2021 |
| NCT03730831 | Unknown status | N/A | Narrative Exposure Therapy in Patients With Psychotic Disorders and a Posttraumatic Stress Disorder | January 1, 2018 | December 31, 2020 |
| NCT00172770 | Unknown status | The Establishment of the Early Intervention Program for Patients With Schizophrenia | August 2004 | July 2006 | |
| NCT00725855 | Unknown status | Phase 2 | A Single-Center, Double-Blind (DB) Study of MEM 3454 on P50 Sensory Gating and Mismatch Negativity in Schizophrenia Patients | August 2008 | April 2009 |
| NCT03781115 | Unknown status | Phase 1 | Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia | November 20, 2017 | January 2023 |
| NCT00480844 | Unknown status | Phase 4 | Comparison of Cognitive Functions of Schizophrenic Patients Treated With Sertindole Versus Risperidone | October 2008 | |
| NCT02431949 | Unknown status | The Music Study in Refractory Psychosis | June 2015 | May 2017 | |
| NCT03729791 | Unknown status | N/A | The Effect of tDCS on Schizophrenia With Negative Symptoms | December 1, 2019 | December 1, 2020 |
| NCT00071604 | Unknown status | N/A | Medication Adherence in Older People With Psychosis | September 2002 | May 2007 |
| NCT04278027 | Unknown status | N/A | Cognitive Remediation Therapy in Schizophrenia: Effects on Epigenetics | January 3, 2017 | June 15, 2020 |
| NCT00563017 | Unknown status | N/A | Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone | October 2004 | November 2005 |
| NCT03802838 | Unknown status | Phase 4 | Clinical Evaluation of Acupuncture Treatment for Negative Symptoms of Schizophrenia | October 1, 2017 | September 30, 2019 |
| NCT05168007 | Unknown status | Phase 3 | Study Evaluating the Efficacy and Safety of WID-RGC20(Cariprazine) in Patients With Schizophrenia | November 19, 2021 | July 31, 2023 |
| NCT04476836 | Unknown status | N/A | Animal-Assisted Therapy in Patients With Schizophrenia | August 1, 2020 | December 1, 2020 |
| NCT02532491 | Unknown status | Phase 4 | Effectiveness of Second Generation Antipsychotics in First Episode Psychosis Patients: 1-year Follow-up | May 2014 | December 2020 |
| NCT01083381 | Unknown status | Phase 2 | Is MS14 Helpful in Schizophrenia? | February 2010 | April 2011 |
| NCT01370291 | Unknown status | Phase 3 | Repetitive Transcranial Magnetic Stimulation for First-episode Schizophrenia Patients | June 2011 | December 2013 |
| NCT01300364 | Unknown status | Phase 4 | Reboxetine and Citalopram as an Adjunct Treatment to Second Generation Antipsychotics in the Treatment of Negative Symptoms of Schizophrenia | November 2008 | |
| NCT02533232 | Unknown status | Phase 1 | Minocycline Augmentation of Clozapine for Treatment Resistant Schizophrenia | August 30, 2022 | December 30, 2022 |
| NCT00560677 | Unknown status | Schizophrenia and PTSD Project: Health, Interventions, and Risk/Resilience Evaluation(SAPPHIRE Study) | March 2007 | December 2023 | |
| NCT04173598 | Unknown status | N/A | Cognitive Remediation Program for Family Caregivers in Schizophrenia | February 6, 2020 | March 2021 |
| NCT00173069 | Unknown status | A Study on Psychopathological Progress of Early Schizophrenia-Like Disorder (SOPRES) | January 2006 | December 2010 | |
| NCT00986167 | Unknown status | Phase 4 | Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry | October 2009 | October 2010 |
| NCT04012684 | Unknown status | N/A | rTMS on Mismatch Negativity of Schizophrenia | September 5, 2019 | February 28, 2021 |
| NCT05498571 | Unknown status | Risk Prediction Model of Cardiovascular Events in Patients With Schizophrenia | December 1, 2021 | December 31, 2022 | |
| NCT03996122 | Unknown status | Research of Anatomo-functional Biomarkers in Schizophrenia | April 4, 2019 | October 4, 2021 | |
| NCT05073640 | Unknown status | Phase 1/Phase 2 | Pentoxifylline Add-on Therapy for Schizophrenia | April 20, 2019 | December 2022 |
| NCT00999505 | Unknown status | Phase 3 | Amantadine as Adjunctive Therapy to Antipsychotics in Schizophrenia | May 2010 | September 2011 |
| NCT02907437 | Unknown status | Phase 3 | Minocycline add-on to Antipsychotics for the Treatment of Negative and Cognitive Symptoms in Schizophrenia | January 2015 | January 2018 |
| NCT00916201 | Unknown status | Phase 1 | Evaluation Study of New Compounds With Potential Use in Schizophrenia | June 2020 | December 2022 |
| NCT03071484 | Unknown status | N/A | Efficacy of Transcranial Direct Current Stimulation in Treatment of Cognitive Deficits in Early Stages of Psychosis | August 2020 | August 2021 |
| NCT05233657 | Unknown status | Phase 1 | A Safety，Tolerability and Pharmacokinetics Clinical Trial of JX11502MA Capsule | January 4, 2020 | February 28, 2022 |
| NCT04020588 | Unknown status | Phase 4 | Anti-inflammatories and Adolescent Schizophrenia | February 25, 2019 | December 2020 |
| NCT00737256 | Unknown status | Phase 2 | A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence | August 2008 | May 2014 |
| NCT02916121 | Unknown status | N/A | Potential Intervention Strategy With Folic Acid and Vitamin B12 in Patients With Schizophrenia | October 2016 | December 2018 |
| NCT03675750 | Unknown status | Effects of Hyperprolactinemia Induced by Antipsychotic Drugs on Bone Metabolism | July 1, 2018 | October 31, 2020 | |
| NCT01563016 | Unknown status | N/A | Glucose as a Mediator of Self-control Performances in Patients With Schizophrenia | April 2012 | April 2013 |
| NCT02337439 | Unknown status | N/A | Perceptual Deficits in Schizophrenia | August 2014 | December 2018 |
| NCT02439099 | Unknown status | Retinoic Acid Homeostasis in Neuropsychiatric Diseases | March 2015 | December 2022 | |
| NCT02715128 | Unknown status | N/A | Disorder-tailored Transcranial Direct Current Stimulation (tDCS) of the Prefrontal Cortex | March 2016 | January 2022 |
| NCT04064476 | Unknown status | The Effect of Long-acting Antipsychotics on Schizophrenia Patients With Violence Risk | August 18, 2019 | September 15, 2021 | |
| NCT02879591 | Unknown status | N/A | Enhancing Social Interaction With an AlterEgo Artificial Agent | April 2014 | September 2016 |
| NCT03999112 | Unknown status | N/A | Effect of Metacognitive Therapy on Negative Symptoms: a Case Series | January 22, 2020 | April 2020 |
| NCT03090503 | Unknown status | Phase 4 | Effectiveness of Second Generation Antipsychotics in First Episode Psychosis Patients: 3-year Follow-up | June 2014 | June 2021 |
| NCT04781179 | Unknown status | N/A | Study of the Effectiveness of Mental Contrasting and Implementation Intention in the Management of Apathy in Schizophrenia | February 22, 2022 | September 2023 |
| NCT03476473 | Unknown status | Early Detection of Respiratory Disorders in Psychosis | February 16, 2018 | December 2020 | |
| NCT02708316 | Unknown status | The Gut Metagenome Research of Schizophrenia | April 2016 | December 2022 | |
| NCT03188133 | Unknown status | N/A | Visual Information Processing in Schizophrenia Patients With Visual Hallucinations | October 17, 2017 | October 31, 2020 |
| NCT04987151 | Unknown status | N/A | The Effects of Different Modalities of Exercise in Patients With Schizophrenia | October 2021 | July 2022 |
| NCT04268797 | Unknown status | N/A | TMS in Treatment of Schizophrenia Negative Symptoms | November 4, 2019 | March 15, 2023 |
| NCT05174533 | Unknown status | Prevalence of Cardiovascular Disorders in Patients Aged 40 and More With Schizophrenia | January 12, 2022 | July 12, 2022 | |
| NCT00182494 | Unknown status | Phase 4 | Diabetes Prevention Program in Schizophrenia [DPPS] | February 2005 | January 2009 |
| NCT03575442 | Unknown status | N/A | "Art Therapy" in Acute Psychiatry | April 1, 2017 | December 2020 |
| NCT02805088 | Unknown status | N/A | Emotions in Schizophrenia and Bipolar Disorders: a Common Vulnerability? | February 2014 | |
| NCT04839926 | Unknown status | Phase 1 | A Single Ascending Dose Study Of CY150112 After Single Oral Administration in Healthy Chinese Subjects | March 2, 2021 | August 1, 2021 |
| NCT03693794 | Unknown status | A Study in Italy About Evidence Based Psychosocial/Rehabilitative Interventions in Patients With Early Schizophrenia Treated Continuously With Antipsychotics | December 15, 2017 | December 1, 2020 | |
| NCT04641780 | Unknown status | "Brexpiprazole (Rexulti™) Safety and Efficacy Among Filipino Patients (RAISE) - A Post Marketing Surveillance Program" | August 17, 2019 | March 2024 | |
| NCT00518999 | Unknown status | Emotional and Cognitive Abilites of Schizophrenia Patients at Various Time Points | August 2007 | August 2008 | |
| NCT01045629 | Unknown status | Competence Ability Study in People With Schizophrenia | October 2009 | June 2010 | |
| NCT03807388 | Unknown status | N/A | ReMindCare App for Patients From First Episode of Psychosis Unit. | September 2019 | September 2023 |
| NCT01477918 | Unknown status | Prevalence of Metabolic Syndrome in Patients With Schizophrenia in Korea | December 2011 | ||
| NCT02926976 | Unknown status | N/A | The Optimal Treatment for Treatment-resistant Schizophrenia | November 2016 | September 2019 |
| NCT01250847 | Unknown status | Phase 4 | Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS) | November 2010 | October 2012 |
| NCT03000985 | Unknown status | N/A | Evaluation of a Psychoeducation Program for Families Caregivers of Schizophrenic Patients : Randomized Study in Two Arms | April 2016 | December 2021 |
| NCT02880995 | Unknown status | N/A | [18 Fluorine(F)]DOPA Determinants and Predictors of Treatment Response in Psychosis | November 1, 2017 | December 2019 |
| NCT04148963 | Unknown status | Phase 3 | A Study of Staccato Loxapine (ADASUVE®) for Inhalation | December 1, 2019 | August 1, 2020 |
| NCT03509597 | Unknown status | N/A | Brain Image Markers Associated With Cognitive Training and Aerobic Exercise in Schizophrenia | March 1, 2017 | June 1, 2020 |
| NCT03702933 | Unknown status | D-serine in Schizophrenia | September 1, 2018 | December 1, 2021 | |
| NCT03130465 | Unknown status | Aripiprazole Once-monthly Versus Daily Oral Atypical Antipsychotic Treatment in Patients With Recent-onset Schizophrenia | July 13, 2017 | January 31, 2020 | |
| NCT01903707 | Unknown status | N/A | Cognitive Remediation in Schizophrenia | May 2013 | October 2015 |
| NCT02245607 | Unknown status | N/A | Compensatory Cognitive Training in Clinical High Risk Latino Youth | October 2014 | February 1, 2021 |
| NCT00220714 | Unknown status | Phase 4 | PREvent First Episode Relapse (PREFER) | November 2004 | December 2007 |
| NCT01167556 | Unknown status | N/A | Family Motivational Intervention in Schizophrenia | March 2006 | February 2011 |
| NCT03237052 | Unknown status | N/A | Validating and Optimizing Model of Antipsychotics Selection | January 1, 2018 | December 2020 |
| NCT03837340 | Unknown status | N/A | Community-based Mental Health Care for People With Severe and Enduring Mental Ill Health | January 1, 2018 | June 1, 2022 |
| NCT03608462 | Unknown status | N/A | Modulation of Repetitive Transcranial Magnetic Stimulation on Hippocampal Neurogenesis and Functional Network in Patients With Schizophrenia | April 1, 2019 | December 31, 2021 |
| NCT03756610 | Unknown status | N/A | Transcranial Alternating Current Stimulation (tACS) for Cognitive Impairments in Patients With Schizophrenia | November 2018 | March 2020 |
| NCT02868307 | Unknown status | N/A | Response Shift and Quality of Life in Patients Suffering From Schizophrenia and Their Caregivers | July 2012 | January 2017 |
| NCT02013232 | Unknown status | N/A | Adjunctive Aripiprazole in the Treatment of Risperidone-Induced Hyperprolactinemia | February 2013 | February 2014 |
| NCT03627377 | Unknown status | N/A | Multi-component Intervention for Diabetes in Adults With Serious Mental Illness | December 28, 2018 | May 31, 2022 |
| NCT03542903 | Unknown status | N/A | ECT in Ultra-resistant Schizophrenia | July 4, 2018 | October 4, 2023 |
| NCT01672554 | Unknown status | Phase 3 | Clinical Benefits of Seroquel XR in Anxiety Disorder | December 2008 | October 2013 |
| NCT04123223 | Unknown status | N/A | Comparing Cognitive Remediation Approaches for Schizophrenia | November 1, 2019 | July 2022 |
| NCT02134418 | Unknown status | N/A | Evaluation of Social Skills Intervention on Cognitive Function in Schizophrenia | March 2015 | March 2016 |
| NCT03883204 | Unknown status | Phase 4 | Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: 3-years Follow-up | January 1, 2015 | December 2020 |
| NCT01215383 | Unknown status | The Antiatherogenic Properties of HDL in Psychiatric Patients With and Without Antipsychotic Therapy | November 2010 | ||
| NCT00138775 | Unknown status | Phase 2 | Israel Multicenter D-Serine Study (IMSER) for the Treatment of Schizophrenia | October 2004 | October 2007 |
| NCT02964923 | Unknown status | Genes Polymorphisms and Metabolic Effects of the Second Generation Antipsychotic Drugs in Patients With Schizophrenia | April 2016 | December 2017 | |
| NCT02714894 | Unknown status | Response to Clozapine in Treatment Resistant Schizophrenia: A Longitudinal Magnetic Resonance Spectroscopy Study | April 2016 | July 30, 2022 | |
| NCT00813436 | Unknown status | Phase 2 | The Effect of Intranasal Administration of Oxytocin on Empathic Abilities. | May 2008 | January 2010 |
| NCT04393896 | Unknown status | N/A | Assessing a WeChat-based Integrative Family Intervention (WIFI) for Schizophrenia | September 1, 2021 | June 30, 2022 |
| NCT00698295 | Unknown status | Linear and Non-linear Analysis of EEG Changes in Schizophrenia After Atypical Antipsychotics Medication | September 2004 | September 2010 | |
| NCT03919760 | Unknown status | Early Psychosis Intervention - Spreading Evidence-based Treatment | January 3, 2020 | May 31, 2024 | |
| NCT05322031 | Unknown status | Phase 4 | The Impact of Aripiprazole Long-acting on Myelin and Cognition in the Onset of Schizophrenia | January 1, 2022 | December 31, 2022 |
| NCT02935998 | Unknown status | Phase 4 | The Efficacy And Safety Of Intramuscular Ziprasidone For Three Days In Patients With Psychotic Agitation | October 2016 | December 2017 |
| NCT00155207 | Unknown status | A Study on Risk Mutations of Vulnerability Genes of Schizophrenia | May 2005 | April 2008 | |
| NCT01075373 | Unknown status | A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations | March 2009 | November 2010 | |
| NCT04314154 | Unknown status | Using Clinical Process Indicators, Patient Reported Outcome Measures (PROMs), and Patient Reported Experience Measures (PREMs) to Improve the Quality and Continuity of Care for Psychiatric Patients | April 15, 2020 | April 15, 2022 | |
| NCT00825045 | Unknown status | N/A | Dopamine D2 and D3 Receptor Occupancy and Clinical Response in Older Patients With Schizophrenia | December 2008 | December 2020 |
| NCT02329119 | Unknown status | N/A | Psychiatric Disorders and Electrophysiological Markers | September 2015 | February 2019 |
| NCT01831986 | Unknown status | N/A | Pregnenolone and L-theanine Augmentation in the Treatment for Schizophrenia and Schizoaffective Disorders | January 2011 | December 2013 |
| NCT02882204 | Unknown status | Tracking Outcomes in Psychosis | March 1, 2016 | December 1, 2023 | |
| NCT00861003 | Unknown status | An Adherence Study of Antipsychotic Medication in Outpatients With Schizophrenia or Schizoaffective Disorder | April 2009 | August 2010 | |
| NCT00567099 | Unknown status | N/A | Remediation of Schizophrenia Sensory Gating Deficit With Aripiprazole | August 2003 | September 2008 |
| NCT02650102 | Unknown status | Phase 1/Phase 2 | The Role of miR-30 Family Dysregulation in Response to Antipsychotic Treatment | January 2013 | December 2016 |
| NCT04432116 | Unknown status | N/A | Time and Virtual Reality in Schizophrenia and Bipolar Disorder | September 2020 | December 2023 |
| NCT00465283 | Unknown status | Phase 4 | Donepezil Double Blind Trial for ECT Memory Disfunction | May 2007 | January 2010 |
| NCT00937261 | Unknown status | Phase 4 | Contrasting the Brain Effects of Risperidone and Invega With Functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) Scanning | July 2009 | January 2011 |
| NCT01398189 | Unknown status | N/A | F-18 Altanserin PET Study of Patients Receiving Clozapine | July 2011 | July 2015 |
| NCT01936220 | Unknown status | N/A | Relapse Prevention in First Episode Schizophrenia: a 5 Year Trial | September 1997 | February 2016 |
| NCT02001103 | Unknown status | Phase 3 | Memantine add-on for Cognitive and Negative Symptoms of Schizophrenia | January 2014 | December 2017 |
| NCT01295411 | Unknown status | N/A | Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia | January 2011 | September 2015 |
| NCT05192304 | Unknown status | Phase 1 | Evaluate the Safety, Tolerability and Pharmacokinetic Profile of TPN672 Tablets Maleate in Patients With Schizophrenia | February 1, 2022 | March 1, 2024 |
| NCT01946295 | Unknown status | Phase 2/Phase 3 | Famotidine in Schizophrenia | March 2014 | August 2016 |
| NCT01167348 | Unknown status | N/A | The Effectiveness Of Auricular Acupressure On Body Weight Parameters On Patients With Schizophrenia | June 2010 | August 2010 |
| NCT00914030 | Unknown status | Visual Exploration and Attention: Studies in Patients With Schizophrenia and Autism Spectrum Disorders | June 2009 | December 2016 | |
| NCT02205437 | Unknown status | Novel Candidate Genes for Treatment Response to Antipsychotics in Schizophrenia | January 2015 | December 2020 | |
| NCT00221585 | Unknown status | The National Danish Schizophrenia Project | October 1997 | July 2005 | |
| NCT01729572 | Unknown status | N/A | Measuring the Effect of Remote Monitoring of Treatment Adherence on the Risk of Re-admission of Ambulatory Schizophrenic Patients | January 2014 | August 2015 |
| NCT00708396 | Unknown status | Phase 4 | Tolerability And Efficacy Of High Dose Escitalopram In The Treatment Of Patients Suffering From Schizophrenia And Obsessive-Compulsive Disorder (OCD) - An Open Label Study | July 2008 | July 2010 |
| NCT00141947 | Unknown status | Phase 3 | Bexarotene Treatment in Schizophrenia | September 2005 | September 2006 |
| NCT01459029 | Unknown status | Phase 2 | High Dose D-Serine as Adjuvant Treatment for Recent Onset Schizophrenia | November 2011 | October 2014 |
| NCT00305474 | Unknown status | Phase 4 | Identification and Treatment of the Liability to Develop Schizophrenia | December 2003 | |
| NCT01362478 | Unknown status | Gene Promoter DNA Methylations and Their Relationships With Endophenotypes in Patients With Schizophrenia | August 2011 | July 2014 | |
| NCT03413527 | Unknown status | Phase 2/Phase 3 | rTMS Treatment for Positive and Negative Symptoms of Schizophrenia | February 2016 | February 2020 |
| NCT01300637 | Unknown status | N/A | Effects of Adjunctive Metformin on Metabolic Profiles in Clozapine-treated Schizophrenic Patients | November 2008 | July 2011 |
| NCT03522220 | Unknown status | N/A | Augmentation of Neuronal Network Plasticity in Schizophrenia | September 1, 2016 | December 31, 2019 |
| NCT02433717 | Unknown status | Phase 4 | A Pharmacokinetic Study of Paliperidone ER | April 2015 | February 2016 |
| NCT00686400 | Unknown status | A German Multicenter Study on Toxoplasma Gondii in First-episode Schizophrenia | May 2008 | May 2011 | |
| NCT02233556 | Unknown status | N/A | Effect of Memantine on ERP in Early Schizophrenia and Healthy Subjects | February 2014 | December 2016 |
| NCT00186771 | Unknown status | Phase 4 | Magnetic Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia | November 2004 | January 2015 |
| NCT04291469 | Unknown status | N/A | Antipsychotic Effects of Probiotics and Prebiotics on Patients With Schizophrenia | March 3, 2022 | December 2022 |
| NCT01012830 | Unknown status | Phase 4 | Huperzine-A to Help With Mental Problems and the Inability to Care for Onself in Patients With Schizophrenia | December 2009 | April 2011 |
| NCT03434210 | Unknown status | N/A | The Effect of a Community-based LAT-treated Management Model on the Violence Risk of Patients With Schizophrenia | May 5, 2018 | October 2020 |
| NCT02665611 | Unknown status | N/A | Remote Monitoring and Support for Patients With Schizophrenia, Schizoaffective or Bipolar Disorder on Adherence | February 2016 | January 2018 |
| NCT04553835 | Unknown status | N/A | Effects of Rhythmic Auditory Stimulation on Movements in Individuals at Risk for Psychotic Onset and Schizophrenia Patients | August 31, 2020 | December 31, 2022 |
| NCT02322918 | Unknown status | The BC Psychosis Program Biobank and Database for Genetic Polymorphisms and Their Associations With Psychosis Disorder | July 2014 | July 2018 | |
| NCT00569504 | Unknown status | Prevalence of the Metabolic Syndrome in SPR Taking Antipsychotics | December 2007 | September 2009 | |
| NCT04093518 | Unknown status | Phase 3 | Estradiol as add-on to Antipsychotics | December 2, 2019 | November 1, 2020 |
| NCT00465920 | Unknown status | Phase 2 | Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis | May 2007 | April 2010 |
| NCT03523741 | Unknown status | Therapeutic Drug Monitoring for Individualized Clozapine Therapy | June 13, 2018 | December 31, 2020 | |
| NCT01375894 | Unknown status | N/A | Body Movement Imitation and Perspective Perception Among Psychiatric Patients | March 2012 | December 2012 |
| NCT01320982 | Unknown status | Phase 3 | Minocycline, Acetylsalicylic Acid or Pramipexole vs Placebo in Patients With Schizophrenia or Schizoaffective Disorder | March 2011 | July 2012 |
| NCT02885792 | Unknown status | N/A | Coronary Artery Disease in Patients Suffering From Schizophrenia | September 2015 | September 2020 |
| NCT02205684 | Unknown status | N/A | Effects of Physical Activity in Psychosis | August 2014 | December 2019 |
| NCT01749124 | Unknown status | N/A | My Coach Connect: An Automated Telephone-based Reporting System for Patients With Mental Illness | December 2012 | June 2017 |
| NCT00418912 | Unknown status | Family Study in Schizophrenia | March 2007 | January 2009 | |
| NCT03965598 | Unknown status | Study on Predictiors and Mechanism of Conversion to Psychosis in Individuals at Ultra-high Risk Group | November 1, 2016 | December 31, 2022 | |
| NCT02197286 | Withdrawn | Phase 2 | Targeted Vitamin D Treatment of Schizophrenia-Associated Hyperprolinemia | February 2015 | |
| NCT01448499 | Withdrawn | N/A | Clozapine Versus Amisulpride in Treatment-resistant Schizophrenia Patients | October 2011 | |
| NCT00964041 | Withdrawn | Phase 4 | Once Weekly D-cycloserine for Schizophrenia | July 2009 | June 2011 |
| NCT01123317 | Withdrawn | N/A | Brain Blood Flow Changes Elicited by Oxytocin in Volunteers With and Without Schizophrenia | July 2010 | January 2013 |
| NCT00189995 | Withdrawn | Phase 3 | Clozapine IM and Aggression in Schizophrenic Patients | ||
| NCT05338424 | Withdrawn | Exercise Target Brain Oscillations in Psychosis | July 1, 2022 | September 30, 2022 | |
| NCT03842345 | Withdrawn | DELPhI Evaluation of Psychiatric Conditions | March 2020 | February 2021 | |
| NCT02240446 | Withdrawn | N/A | Non-Invasive Brain Stimulation for Medication-Resistant Auditory Hallucinations in Schizophrenia Patients | June 2013 | December 2018 |
| NCT00672464 | Withdrawn | Phase 4 | Cardio Risk of Acute Schizophrenia Olanzapine Duke | April 2008 | February 2010 |
| NCT00988728 | Withdrawn | Phase 2 | Efficacy & Safety of SCH 900435 in Schizophrenia (Study P06079)(WITHDRAWN) | February 2011 | July 2012 |
| NCT02603458 | Withdrawn | Phase 2 | NRX-1074 in Early Course Schizophrenia | ||
| NCT00838227 | Withdrawn | Phase 2 | Modafinil Augmentation in Chronic Schizophrenia and Schizoaffective Disorder | February 2008 | June 2012 |
| NCT03736291 | Withdrawn | N/A | The Effect of Repetitive Transcranial Magnetic Stimulation in Schizophrenia | December 2019 | June 2021 |
| NCT03994965 | Withdrawn | Phase 2 | The Sub-Sero Study | January 2020 | January 2025 |
| NCT01758887 | Withdrawn | Antipsychotic Discontinuation in High-risk Subjects | December 2012 | September 2016 | |
| NCT00892021 | Withdrawn | Phase 1 | Study Evaluating the Effects of Multiple Doses of NSA-789 in Subjects With Schizophrenia or Schizoaffective Disorder | May 2009 | October 2009 |
| NCT01584466 | Withdrawn | N/A | Long Acting Paliperidone in Dually Diagnosed People With Schizophrenia: An Open-label Pilot Study | January 2014 | January 2014 |
| NCT03464162 | Withdrawn | N/A | OnTrackNY With the Option of Social Network Meetings | April 11, 2018 | January 11, 2019 |
| NCT03407950 | Withdrawn | N/A | Cognitive Remediation Program for Hospitalized in the Long Term Patients With Deficit Schizophrenia | January 2018 | September 2021 |
| NCT03062553 | Withdrawn | N/A | Enhancement of Treatment of Delusions in Schizophrenia Through Neuromodulation | February 1, 2019 | December 15, 2020 |
| NCT03263533 | Withdrawn | Early Phase 1 | HDAC Inhibitor Augmentation to Clozapine | April 2017 | February 2019 |
| NCT01981811 | Withdrawn | Phase 2 | Adherence to Treatment, Safety and Tolerability Study of the Medical Information Device #1 (MIND1) in Subjects With Schizophrenia or Bipolar I Disorder | March 2014 | December 2014 |
| NCT03271814 | Withdrawn | Phase 1 | Brain Biomarker on Inflammation Response | January 1, 2025 | December 15, 2025 |
| NCT01623726 | Withdrawn | Phase 2 | Transcranial Direct Current Stimulation (tDCS) as Therapeutical Strategy for Negative Symptoms in Schizophrenia | August 2012 | August 2014 |
| NCT05119894 | Withdrawn | Phase 1 | A Clinical Pharmacology Trial of Brexpiprazole Long Acting Injectable (LAI) Administered as a Single Dose in Patients With Schizophrenia | November 22, 2021 | December 6, 2021 |
| NCT03497299 | Withdrawn | Phase 2 | Combining rTMS With Varenicline to Prevent Smoking Lapse in Schizophrenia | July 1, 2018 | August 31, 2022 |
| NCT01567124 | Withdrawn | Phase 4 | Alleviating the Metabolic Side Effects of Antipsychotic Medications | May 2012 | |
| NCT00768612 | Withdrawn | Phase 2 | Study Evaluating Safety and Tolerability of Vabicaserin in Patients With Sudden Worsening of Schizophrenia | November 2008 | July 2009 |
| NCT00440843 | Withdrawn | Phase 3 | Zyprexa and Task Engagement in Schizophrenia | February 2007 | June 2012 |
| NCT00000372 | Withdrawn | Phase 3 | Glycine and D-Cycloserine in Schizophrenia | March 1998 | November 2005 |
| NCT03999190 | Withdrawn | Imaging Dopamine D2 Agonist Binding Sites in Schizophrenia | July 2019 | July 2025 | |
| NCT03071939 | Withdrawn | N/A | Cognate Patient Care Insight Scale | January 2, 2018 | April 2, 2020 |
| NCT01246128 | Withdrawn | Nicotinic Receptor Density in Smoking and Nonsmoking Schizophrenics | October 31, 2010 | July 12, 2011 | |
| NCT00801567 | Withdrawn | N/A | Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic Stimulation | June 2010 | June 2010 |
| NCT04068857 | Withdrawn | N/A | Repetitive Transcranial Magnetic Stimulation (rTMS) Self-Referential Processing (rTMS-SRP) | September 2019 | December 2020 |
| NCT04065360 | Withdrawn | N/A | Group Cognitive Behavioural Family Intervention (CBFI) for People With Schizophrenia and Their Families | January 2021 | December 2022 |
| NCT02661347 | Withdrawn | N/A | Transcranial Direct Current Stimulation for Hallucinations in First-Episode Schizophrenia | February 2016 | December 1, 2016 |
| NCT04054973 | Withdrawn | Phase 2 | L-arginine Study for Persistent Symptoms of Schizophrenia | September 11, 2019 | December 31, 2021 |
| NCT01193166 | Withdrawn | Phase 4 | Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital | August 2010 | September 2012 |
| NCT00425815 | Withdrawn | Phase 2 | Org 24448 (Ampakine) for Cognitive Deficits in Schizophrenia | April 2009 | April 2009 |
| NCT00934908 | Withdrawn | N/A | Prevention of Weight Gain and Dyslipidemia by Green Tea in Patients Initiating Therapy With Olanzapine | March 2009 | March 2009 |
| NCT02286206 | Withdrawn | Phase 4 | Study of the Effect of Dosing on Clozapine Levels | January 2015 | December 2017 |
| NCT00781794 | Withdrawn | Phase 1 | Study Evaluating The Effects Of Single Oral Doses Of NSA-789 On Auditory P50 Suppression In Schizophrenic Patients | January 2009 | August 2009 |
| NCT02538081 | Withdrawn | Phase 1/Phase 2 | Nicotinic Receptors and Schizophrenia | August 2015 | August 2016 |
| NCT00534898 | Withdrawn | Phase 3 | Bexarotene and Fenretinide as Addition to Antipsychotic Treatment in Schizophrenia Patients | ||
| NCT03061136 | Withdrawn | Phase 4 | Clonazepam Effects on Brain Oscillations and Cognition in Schizophrenia | October 2016 | October 2017 |
| NCT00743847 | Withdrawn | Phase 2 | A 6-Week Multicenter Trial Of Varenicline Tartrate For Cognitive Impairment In Subjects With Schizophrenia | March 2009 | November 2009 |
| NCT05140135 | Withdrawn | N/A | Effectiveness and Mechanisms of Recovery Oriented Cognitive Therapy | January 11, 2021 | December 31, 2025 |
| NCT02758067 | Withdrawn | Phase 3 | Comparison of the Effectiveness of Brexpiprazole With That of Risperidone | June 2016 | |
| NCT00702793 | Withdrawn | Phase 4 | Safety and Tolerability of Varenicline in Schizophrenia (SATOVA) | April 2008 | May 2012 |
| NCT03758495 | Withdrawn | Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and Depression | November 1, 2018 | November 2, 2018 | |
| NCT01905605 | Withdrawn | Phase 1/Phase 2 | Phosphatidylcholine Supplementation in Infants | September 2013 | January 2017 |
- Disase is a (Disease Ontology)
- DOID:2468
- Cross Reference ID (Disease Ontology)
- ICD10CM:F20
- Cross Reference ID (Disease Ontology)
- ICD9CM:295
- Cross Reference ID (Disease Ontology)
- MESH:D012559
- Cross Reference ID (Disease Ontology)
- MIM:181500
- Cross Reference ID (Disease Ontology)
- NCI:C3362
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:58214004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0036341
- Exact Synonym (Disease Ontology)
- schizophrenia-1
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0100753
- ICD10 preferred id (Insert disease from ICD10)
- D0004477
- ICD10 class code (Insert disease from ICD10)
- F20