Glioma
Information
- Disease name
- Glioma
- Disease ID
- Description
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| SETD2 | 3 | 47,016,436 | 47,164,113 | 8 |
| TP53 | 17 | 7,668,421 | 7,687,490 | 8 |
| IDH1 | 2 | 208,236,265 | 208,254,322 | 6 |
| PTEN | 10 | 87,863,625 | 87,971,930 | 6 |
| PBRM1 | 3 | 52,547,990 | 52,679,713 | 4 |
| PIK3CA | 3 | 179,148,357 | 179,240,093 | 4 |
| IDH1 | 2 | 208,236,265 | 208,254,322 | 4 |
| CDKN2A | 9 | 21,968,056 | 21,974,866 | 4 |
| EGFR | 7 | 55,019,017 | 55,211,628 | 4 |
| RB1 | 13 | 48,303,751 | 48,481,890 | 2 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05611645 | Active, not recruiting | Phase 2 | Low-dose Bevacizumab With HSRT vs BVZ Alone for GBM at First Recurrence | October 1, 2022 | December 2025 |
| NCT01638533 | Active, not recruiting | Phase 1 | Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction | June 12, 2012 | March 5, 2025 |
| NCT03532295 | Active, not recruiting | Phase 2 | Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas | April 20, 2020 | April 25, 2026 |
| NCT03050736 | Active, not recruiting | Phase 2 | Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression | December 17, 2017 | December 30, 2023 |
| NCT03030066 | Active, not recruiting | N/A | Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas | January 19, 2017 | March 1, 2026 |
| NCT02781792 | Active, not recruiting | Phase 2 | Temozolomide Chronotherapy for High Grade Glioma | August 11, 2016 | July 14, 2024 |
| NCT02717962 | Active, not recruiting | Phase 2 | Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting | January 20, 2017 | March 30, 2024 |
| NCT02658279 | Active, not recruiting | N/A | Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype | January 22, 2016 | January 2025 |
| NCT03514069 | Active, not recruiting | Phase 1 | Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma | June 5, 2018 | December 31, 2024 |
| NCT02549833 | Active, not recruiting | Phase 1 | Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma | October 17, 2016 | August 31, 2024 |
| NCT03739372 | Active, not recruiting | N/A | Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma | November 28, 2018 | January 1, 2027 |
| NCT02481349 | Active, not recruiting | N/A | Couples-Based Yoga Program in Improving Quality of Life in Patients With High-Grade Glioma Undergoing Radiation Therapy and Their Partners | June 16, 2015 | April 30, 2025 |
| NCT06036381 | Active, not recruiting | Spatial and Temporal Characterization of Gliomas Using Radiomic Analysis | February 15, 2024 | December 2026 | |
| NCT02481154 | Active, not recruiting | Phase 1 | Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation | June 2015 | March 2024 |
| NCT03500991 | Active, not recruiting | Phase 1 | HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors | July 26, 2018 | July 26, 2039 |
| NCT02465060 | Active, not recruiting | Phase 2 | Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) | August 17, 2015 | December 31, 2025 |
| NCT03496181 | Active, not recruiting | Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently | March 30, 2018 | September 2024 | |
| NCT03343197 | Active, not recruiting | Phase 1 | Study of AG-120 and AG-881 in Subjects With Low Grade Glioma | March 20, 2018 | May 2025 |
| NCT03295396 | Active, not recruiting | Phase 2 | ONC201 in Adults With Recurrent H3 K27M-mutant Glioma | October 31, 2017 | September 30, 2023 |
| NCT03638167 | Active, not recruiting | Phase 1 | EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors | March 19, 2019 | March 2040 |
| NCT04539574 | Active, not recruiting | N/A | An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors | September 4, 2020 | December 31, 2024 |
| NCT04521686 | Active, not recruiting | Phase 1 | Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations | October 16, 2020 | May 2025 |
| NCT01743950 | Active, not recruiting | Phase 2 | A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab | December 3, 2012 | December 2025 |
| NCT01204684 | Active, not recruiting | Phase 2 | Dendritic Cell Vaccine for Patients With Brain Tumors | October 8, 2010 | January 31, 2026 |
| NCT04870580 | Active, not recruiting | N/A | [18F] FDOPA PET Imaging in Glioma: Feasibility Study for PET Guided Brain Biopsy | September 1, 2021 | May 1, 2024 |
| NCT03180502 | Active, not recruiting | Phase 2 | Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma | August 2, 2017 | January 2030 |
| NCT01682187 | Active, not recruiting | Phase 1 | A Dose-Escalation Study in Participants With Recurrent Malignant Glioma | December 15, 2005 | September 30, 2024 |
| NCT04617002 | Available | Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas | |||
| NCT05592743 | Available | Vorasidenib Expanded Access Program | |||
| NCT00424554 | Completed | Phase 2 | Low-dose Temozolomide for 2 Weeks on Brain Tumor Enzyme in Patients With Gliomas (P04602 AM1) (Completed) | September 26, 2006 | February 16, 2011 |
| NCT00463203 | Completed | Phase 2 | Bevacizumab and Irinotecan for Patients With Primary Brain Tumors and Progression After Standard Therapy | March 2007 | June 2011 |
| NCT00526812 | Completed | Phase 1 | A Safety Study of RTA 744 in Patients With Recurrent High-Grade Gliomas | November 30, 2005 | |
| NCT00532948 | Completed | Phase 1 | A Study of Xeloda (Capecitabine) Plus Radiation Therapy in Children With Newly Diagnosed Gliomas | May 2007 | October 2010 |
| NCT00694330 | Completed | Phase 1 | Vaccination With Lethally Irradiated Glioma Cells Mixed With GM-K562 Cells in Patients Undergoing Craniotomy For Recurrent Tumor | June 2008 | August 2009 |
| NCT00705198 | Completed | Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062) | September 2006 | July 2016 | |
| NCT00723827 | Completed | Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2) | March 2008 | September 2011 | |
| NCT00727506 | Completed | Phase 2 | BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant Glioma | July 14, 2008 | May 25, 2016 |
| NCT00782626 | Completed | Phase 2 | Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas | June 2009 | August 2012 |
| NCT00795457 | Completed | Early Phase 1 | Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas | January 2009 | July 2015 |
| NCT00795665 | Completed | Phase 2 | Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma | June 2008 | December 2015 |
| NCT00939315 | Completed | Multimodal Diagnostic Assessment of Cerebral Gliomas With FET & FCH PET/CT, and Magnetic Resonance Imaging/Spectroscopy | July 2009 | January 2016 | |
| NCT00979173 | Completed | Phase 1 | Pharmacokinetics (PK) Study of AC480 for Recurrent Glioma | November 2009 | June 2012 |
| NCT00979810 | Completed | N/A | Image-Guided Stereotactic Biopsy of High Grade Gliomas | September 16, 2009 | February 24, 2020 |
| NCT01020292 | Completed | Phase 1 | A Trial of the Protease Inhibitor Nelfinavir and Concurrent Radiation and Temozolomide in Patients With WHO Grade IV Glioma | April 2009 | December 2017 |
| NCT01081223 | Completed | Phase 1/Phase 2 | Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma | April 2010 | March 2011 |
| NCT01125800 | Completed | Phase 1/Phase 2 | A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB | February 2011 | October 2014 |
| NCT01137604 | Completed | Phase 2 | A Study in Subjects With Recurrent Malignant Glioma | November 9, 2010 | October 28, 2014 |
| NCT01138813 | Completed | Development of Magnetic Resonance Spectroscopy (MRS) Biomarkers of Tumor Metabolism (MK-0000-145) | March 2009 | February 2010 | |
| NCT01140568 | Completed | Phase 2 | Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant Gliomas | April 21, 2010 | January 2019 |
| NCT01158651 | Completed | Phase 2 | Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas | July 10, 2010 | October 26, 2017 |
| NCT01166308 | Completed | N/A | Carbon Ion Radiotherapy for Recurrent Gliomas | December 2010 | April 2016 |
| NCT01212731 | Completed | Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study | September 2010 | October 17, 2017 | |
| NCT01220271 | Completed | Phase 1/Phase 2 | A Study Combining LY2157299 With Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma | April 2011 | November 2016 |
| NCT01331135 | Completed | Phase 1 | Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors | April 2011 | August 9, 2017 |
| NCT00001148 | Completed | Detecting Malignant Brain Tumor Cells in the Bloodstream During Surgery to Remove the Tumor | October 1999 | January 2005 | |
| NCT00001171 | Completed | Evaluation of Factors in Human Brain Tumors | July 1979 | September 2005 | |
| NCT00001502 | Completed | Phase 1 | A Pediatric Phase I Trial of RMP-7 and Carboplatin in Brain Tumors | April 1996 | March 2000 |
| NCT00001573 | Completed | Phase 1 | A Phase I Study of SU101 in Pediatric Patients With Refractory Malignancy | March 1997 | May 2000 |
| NCT00009035 | Completed | Natural History of Patients With Brain and Spinal Cord Tumors | January 22, 2001 | September 11, 2018 | |
| NCT00028158 | Completed | Phase 1/Phase 2 | Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain Cancer | December 2001 | October 2003 |
| NCT00038441 | Completed | Phase 1/Phase 2 | Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas | September 1995 | August 2005 |
| NCT00040573 | Completed | Phase 1/Phase 2 | Safety and Tolerability Study of 131I-TM-601 to Treat Adult Patients With Recurrent Glioma. | June 2002 | August 2003 |
| NCT00047879 | Completed | Phase 2 | Phase II Trial of Peginterferon Alpha-2b and Thalidomide in Adults With Recurrent Gliomas | October 2002 | June 2009 |
| NCT00059020 | Completed | The Role of Gene Changes in Brain Tumor Formation and Growth | April 2003 | November 2004 | |
| NCT00080054 | Completed | Phase 1 | A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas | ||
| NCT00107003 | Completed | Phase 2 | GW572016 to Treat Recurrent Malignant Brain Tumors | March 30, 2005 | November 30, 2012 |
| NCT00108069 | Completed | Phase 2 | Tamoxifen and Bortezomib to Treat Recurrent Brain Tumors | April 2005 | March 2013 |
| NCT00137488 | Completed | Angiogenic Profile and Non-invasive Imaging May Predict Tumor Progression of High Risk Group Low Grade Glioma (LGG) | November 2005 | ||
| NCT00147160 | Completed | Phase 2 | Phase II Cisplatin + Temozolomide in Malignant Glial Tumours in Children and Adolescents | October 2003 | December 2007 |
| NCT00165360 | Completed | Phase 2 | Prolonged Daily Temozolomide for Low-Grade Glioma | September 2001 | September 2009 |
| NCT00185848 | Completed | Phase 1 | Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis | April 2005 | June 2013 |
| NCT00213278 | Completed | Phase 2 | Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma | January 2002 | September 2012 |
| NCT00214175 | Completed | Determination of Fraction Size Equivalent Dose (FED) Levels for Intracranial Conformal Avoidance Radiotherapy | June 2004 | January 2011 | |
| NCT00250211 | Completed | Phase 1/Phase 2 | Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide | March 2005 | April 2011 |
| NCT00338026 | Completed | Phase 1 | A Phase I Study of ECO-4601 in Patients With Advanced Cancer | February 2006 | August 2007 |
| NCT00339352 | Completed | A Family Study of Adults With Glioma | March 11, 1999 | December 3, 2020 | |
| NCT00350727 | Completed | Phase 2 | Pazopanib In Combination With Lapatinib In Adult Patients With Relapsed Malignant Glioma | December 2006 | December 2009 |
| NCT00352820 | Completed | Experience of Brain Tumor Caregivers | April 2006 | December 2006 | |
| NCT00379132 | Completed | Phase 1 | 131-I-TM-601 Study in Adults With Solid Tumors | August 2006 | August 2008 |
| NCT00392171 | Completed | Phase 2 | The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601) | June 9, 2006 | September 15, 2009 |
| NCT00404495 | Completed | Phase 2 | Combination of Irinotecan and Temozolomide in Children With Brain Tumors. | April 2007 | December 2011 |
| NCT00409214 | Completed | Phase 2 | Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litx™ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma | November 2006 | |
| NCT00412542 | Completed | Phase 2 | Thalidomide and Temozolomide or Camptothecin-11 (CPT-11) in Patients With Gliomas | October 2003 | October 2009 |
| NCT01394692 | Completed | N/A | Comparative Study of Intraoperative MRI-guided vs. Conventional Glioma Surgery | October 2007 | January 2011 |
| NCT01450826 | Completed | Phase 2 | Emend and Ondansetron Compared to Ondansetron Alone to Prevent CINV in Glioma Patients Receiving Temozolomide | June 24, 2014 | April 21, 2017 |
| NCT01460706 | Completed | Phase 2/Phase 3 | Imaging Malignant Glioma With 68Ga-DOTATOC PET/CT | October 2011 | December 2013 |
| NCT01465347 | Completed | Phase 1/Phase 2 | Safety and Efficacy of Trans Sodium Crocetinate (TSC) With Radiation and Temozolomide in Newly Diagnosed Glioblastoma | February 2012 | February 2016 |
| NCT01478178 | Completed | Phase 1/Phase 2 | Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma | October 2011 | October 2016 |
| NCT01479686 | Completed | Phase 3 | iMRI Guided Resection in Cerebral Glioma Surgery | September 2011 | March 2021 |
| NCT01491893 | Completed | Phase 1 | PVSRIPO for Recurrent Glioblastoma (GBM) | April 25, 2012 | October 1, 2021 |
| NCT01502280 | Completed | Phase 3 | Fluorescence-guided Surgery for Low- and High-grade Gliomas | November 2010 | June 2018 |
| NCT01595139 | Completed | MicroRNAs in Patients With Neurofibromatosis Type 1 | February 2012 | July 2015 | |
| NCT01598454 | Completed | Phase 1 | Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides | February 2011 | June 2015 |
| NCT01661400 | Completed | Phase 1 | Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors | October 26, 2012 | December 27, 2023 |
| NCT01792310 | Completed | Phase 1/Phase 2 | A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours | May 2013 | September 2016 |
| NCT01811524 | Completed | The Etiology and Progression of Brain Tumors | September 1983 | March 2012 | |
| NCT01813877 | Completed | N/A | Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma | August 22, 2012 | January 14, 2020 |
| NCT01836536 | Completed | N/A | Search for a Link Between Response to Treatment and Circulating Leucocytes in High Grade Glioma Patients | September 2012 | August 2015 |
| NCT01967810 | Completed | Phase 2 | ANG1005 in Patients With Recurrent High-Grade Glioma | October 2013 | September 2017 |
| NCT01999270 | Completed | Phase 1 | Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors | April 2013 | May 2016 |
| NCT02010606 | Completed | Phase 1 | Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma | January 8, 2014 | July 10, 2021 |
| NCT02022800 | Completed | N/A | Prospective Study on Oncologic Cerebral Imagery Contribution by 18F-FDOPA Position Emission Tomography (PET) | November 2013 | June 2016 |
| NCT02052648 | Completed | Phase 1/Phase 2 | Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors | March 2014 | June 20, 2019 |
| NCT02073994 | Completed | Phase 1 | Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation | March 1, 2014 | January 4, 2024 |
| NCT02082119 | Completed | N/A | Hypofractionated IMRT With Temozolomide for HGG | July 2013 | May 2016 |
| NCT02099487 | Completed | Phase 2 | Hypofractionated Imrt (Vmat-Ra) For Elderly Patients With Newly Diagnosed High Grade Glioma | July 2013 | May 2016 |
| NCT02105233 | Completed | Phase 1 | Improving Ultrasound Images in Brain Tumor Surgery With the Use of Brain Mimicking Fluid | February 2014 | May 2016 |
| NCT02115074 | Completed | Phase 1 | Safety of Fluvastatin-Celebrex Association in Low-grade and High Grade Optico-chiasmatic Gliomas | June 2014 | January 2022 |
| NCT02122822 | Completed | Phase 1 | Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96 | July 2013 | May 2017 |
| NCT02162732 | Completed | N/A | Molecular-Guided Therapy for Childhood Cancer | July 8, 2014 | January 18, 2024 |
| NCT02234297 | Completed | Phase 1 | Safety Study of BLZ-100 in Adult Subjects With Glioma Undergoing Surgery | October 2014 | March 2016 |
| NCT02253212 | Completed | Phase 1/Phase 2 | Safety of BBB Opening With the SonoCloud | July 2014 | July 2018 |
| NCT02273739 | Completed | Phase 1/Phase 2 | Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation | December 8, 2014 | June 3, 2016 |
| NCT02439164 | Completed | N/A | Sedatives' Effects on Neurological Function in Patients With Eloquent Area Glioma | May 26, 2015 | March 21, 2017 |
| NCT02444546 | Completed | Phase 1 | Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors | June 21, 2015 | November 21, 2022 |
| NCT02454634 | Completed | Phase 1 | Phase I Trial of IDH1 Peptide Vaccine in IDH1R132H-mutated Grade III-IV Gliomas | June 2015 | September 19, 2017 |
| NCT02496741 | Completed | Phase 1/Phase 2 | Metformin And Chloroquine in IDH1/2-mutated Solid Tumors | November 2015 | November 18, 2019 |
| NCT02502708 | Completed | Phase 1 | Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors | October 2015 | February 28, 2020 |
| NCT02518061 | Completed | 11C-Methionine PET as Prognostic Marker of Gliomas | July 2015 | December 31, 2018 | |
| NCT02520492 | Completed | N/A | Non Invasive Measurements of Intracranial Pressure in Patients With Malignant Glioma | April 3, 2015 | January 15, 2020 |
| NCT02666066 | Completed | Radiomics for Prediction of Survival in GBM | January 2016 | July 2018 | |
| NCT02678975 | Completed | Phase 2/Phase 3 | Disulfiram in Recurrent Glioblastoma | January 2017 | January 15, 2021 |
| NCT02717455 | Completed | Phase 1 | Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma | June 28, 2016 | March 31, 2024 |
| NCT02728024 | Completed | Assessing Psychosocial and Supportive Care Needs in Patients With Gliomas | March 2014 | June 2015 | |
| NCT02747407 | Completed | Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors | May 2016 | September 9, 2021 | |
| NCT02798406 | Completed | Phase 2 | Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects | October 6, 2016 | June 30, 2021 |
| NCT02805179 | Completed | Phase 2 | A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma | September 22, 2016 | November 18, 2020 |
| NCT02854644 | Completed | N/A | Study of the Anti-tumoral Immune Response | January 27, 2014 | October 27, 2021 |
| NCT02879682 | Completed | Phase 2/Phase 3 | nTMS for Motor Mapping of Rolandic Lesions | August 2016 | April 2023 |
| NCT02901925 | Completed | Early Phase 1 | A Microdose Evaluation Study of ABY-029 in Recurrent Glioma | February 13, 2017 | June 29, 2021 |
| NCT02919865 | Completed | N/A | MR Perfusion Methods in Patients With Suspected Recurrent High Grade Gliomas | December 13, 2017 | August 3, 2021 |
| NCT02960230 | Completed | Phase 1/Phase 2 | H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas | November 18, 2016 | December 31, 2023 |
| NCT02978261 | Completed | Phase 1 | Study of a c-Met Inhibitor PLB1001 in Patients With PTPRZ1-MET Fusion Gene Positive Recurrent High-grade Gliomas | September 2016 | December 2018 |
| NCT03009318 | Completed | N/A | MRS and 11C-methionine PET/CT in the Diagnosis of Glioma | January 2012 | December 2017 |
| NCT03027388 | Completed | Phase 2 | Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma | January 9, 2019 | August 31, 2022 |
| NCT03072134 | Completed | Phase 1 | Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma | April 24, 2017 | July 1, 2021 |
| NCT03082846 | Completed | N/A | Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial | January 1, 2014 | December 3, 2016 |
| NCT03212157 | Completed | N/A | GlucoCEST MRI in Oncology | January 6, 2017 | October 8, 2019 |
| NCT03242824 | Completed | Phase 2 | The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma | September 29, 2017 | June 16, 2021 |
| NCT03257618 | Completed | N/A | Quality of Life and Neurocognitive Functioning | July 27, 2017 | December 31, 2021 |
| NCT03323450 | Completed | N/A | Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory | October 20, 2017 | June 1, 2020 |
| NCT03434262 | Completed | Phase 1 | SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors | March 5, 2018 | May 24, 2024 |
| NCT03551249 | Completed | N/A | Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption | March 26, 2019 | December 31, 2023 |
| NCT03626896 | Completed | N/A | Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients | August 17, 2018 | June 19, 2019 |
| NCT03706625 | Completed | Integrated Discovery of New Immuno-Molecular Actionable Biomarkers for Tumors With Immune-suppressed Environment | November 20, 2018 | July 6, 2023 | |
| NCT03722355 | Completed | Phase 3 | Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma | November 9, 1990 | October 18, 2002 |
| NCT03877861 | Completed | Validation of Readiband™ Actigraph and Associated Sleep/Wake Classification Algorithms | March 15, 2018 | May 1, 2021 | |
| NCT03900689 | Completed | Social Determinants of Health in Glioblastoma Population | May 22, 2019 | March 27, 2022 | |
| NCT03973892 | Completed | Remote Brain Microhaemorrhages May Predict Haematoma in Glioma Patients Treated With Radiation Therapy | January 2015 | January 2016 | |
| NCT04001257 | Completed | 18F-Fluoro-Ethyl-Tyrosine (FET) Positron Emission Tomography (PET) and Grading Glioma | June 17, 2019 | September 17, 2019 | |
| NCT04055688 | Completed | Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas | August 15, 2019 | February 23, 2021 | |
| NCT04056910 | Completed | Phase 2 | Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant Tumors | September 20, 2021 | November 13, 2023 |
| NCT04097535 | Completed | Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRI | December 6, 2018 | August 7, 2020 | |
| NCT04114370 | Completed | Early Phase 1 | Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma | October 22, 2019 | September 30, 2021 |
| NCT04205357 | Completed | Phase 1 | Sulfasalazine and Stereotactic Radiosurgery for Recurrent Glioblastoma | March 1, 2020 | October 14, 2022 |
| NCT04423094 | Completed | Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas | November 1, 2016 | March 30, 2019 | |
| NCT04446416 | Completed | N/A | Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients | July 21, 2020 | August 4, 2023 |
| NCT04719806 | Completed | MR Textural Analysis in Low Grade Gliomas | January 1, 2010 | May 1, 2019 | |
| NCT04752267 | Completed | Early Phase 1 | 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases | February 15, 2021 | September 18, 2023 |
| NCT04809597 | Completed | Does Notch Regulate Glioma Proliferation ? | January 1, 2012 | January 20, 2021 | |
| NCT05028400 | Completed | N/A | Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery | February 1, 2022 | March 11, 2022 |
| NCT05039346 | Completed | Quality of Life and Patient Needs in Advanced High Grade Gliomas | February 11, 2012 | January 30, 2023 | |
| NCT05604365 | Completed | N/A | FearLess in Cognitively Intact Patients With Glioma | November 7, 2022 | November 14, 2023 |
| NCT05873946 | Completed | Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma Surgery | June 1, 2018 | July 30, 2023 | |
| NCT06199388 | Completed | Development and Validation of a Deep Learning-Based Survival Prediction Model for Pediatric Glioma Patients: A Retrospective Study Using the SEER Database and Chinese Data | September 20, 2022 | December 20, 2023 | |
| NCT05739500 | Enrolling by invitation | MRI-based Computer Aided Diagnosis Software (V1) for Glioma | December 1, 2022 | December 31, 2025 | |
| NCT03134131 | No longer available | Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline High Grade Gliomas | |||
| NCT05392374 | No longer available | Expanded Access Use of ONC201 in a Patient With Diffuse Intrinsic Pontine Gliomas | |||
| NCT06413706 | Not yet recruiting | Phase 2 | A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy | June 2024 | February 2028 |
| NCT05958472 | Not yet recruiting | Navigating the Clinical Research Process for Glioma | August 2024 | August 2026 | |
| NCT05788445 | Not yet recruiting | N/A | High-frequency nrTMS on the Contralateral Broca Mirror Area for Glioma Patients With Early Postoperative Aphasia | April 2023 | May 2025 |
| NCT05555550 | Not yet recruiting | Early Phase 1 | Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG | July 2024 | September 2026 |
| NCT05901844 | Not yet recruiting | N/A | Evaluate the Accuracy of Raman IVD Analyzer in the Diagnosis of Gliomas During Surgery | June 2023 | October 2024 |
| NCT05460507 | Not yet recruiting | Phase 1 | Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment | January 2, 2023 | January 31, 2025 |
| NCT05707728 | Not yet recruiting | Evaluation of Role of Intraoperative Ultrasound in Gross Total Resection of Gliomas | March 2023 | October 2024 | |
| NCT06408428 | Not yet recruiting | N/A | Glioma Intraoperative MicroElectroCorticoGraphy | September 2024 | October 2026 |
| NCT06397560 | Not yet recruiting | N/A | PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial | June 2024 | June 2028 |
| NCT05850377 | Not yet recruiting | 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas | June 1, 2023 | May 31, 2026 | |
| NCT05140785 | Not yet recruiting | N/A | Mapping Molecular Markers of Brain Tumour Activity Using MRI | May 1, 2022 | May 1, 2027 |
| NCT06099743 | Not yet recruiting | N/A | ASCENT Intervention for Brain Tumor Patients | May 1, 2024 | May 1, 2029 |
| NCT06241391 | Not yet recruiting | N/A | Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas | February 2024 | February 2025 |
| NCT06329570 | Not yet recruiting | Phase 1/Phase 2 | Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) | July 1, 2024 | March 31, 2027 |
| NCT06043765 | Not yet recruiting | N/A | Reducing Cognitive Impairment in Glioma With Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training | September 2023 | August 2026 |
| NCT06116903 | Not yet recruiting | N/A | Clinical Relevance of Detecting Molecular Abnormalities in Glial Tumor Exosomes | December 15, 2023 | December 15, 2025 |
| NCT06344130 | Not yet recruiting | Phase 1 | Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma | June 23, 2024 | December 31, 2027 |
| NCT06368310 | Not yet recruiting | N/A | FIH Clinical Investigation of Graphene Electrodes for Brain Mapping | May 28, 2024 | January 31, 2025 |
| NCT04745156 | Not yet recruiting | N/A | A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas | August 1, 2024 | September 2025 |
| NCT05700071 | Not yet recruiting | N/A | MRS of Glioma Genomics | February 15, 2023 | November 24, 2026 |
| NCT06368934 | Not yet recruiting | N/A | Sub-lobectomy for IDH Wild-type and TERT Promoter Mutant Glioblastoma | April 8, 2024 | June 2027 |
| NCT06417372 | Not yet recruiting | Intraoperative Fluorescent Staining Combined With Microsurgery for Gliomas | May 15, 2024 | December 31, 2025 | |
| NCT06180434 | Not yet recruiting | Short Term Outcomes After PRoton And photoN radiOtherapy for IDH Mutated Grade 2 and 3 Gliomas | February 1, 2024 | November 1, 2025 | |
| NCT06043232 | Recruiting | MMR/MSI Phenotypes in Prediction of Tumor Vaccine Benefit for Gliomas | September 2023 | March 2026 | |
| NCT05580562 | Recruiting | Phase 3 | ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) | January 23, 2023 | August 2026 |
| NCT03048084 | Recruiting | Phase 4 | Seizure Treatment in Glioma | February 1, 2018 | January 1, 2028 |
| NCT05577416 | Recruiting | Early Phase 1 | A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma | October 11, 2022 | December 1, 2025 |
| NCT05576103 | Recruiting | Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients | January 2015 | December 2026 | |
| NCT06055517 | Recruiting | N/A | Use of Pulsed Low-dose Rate Re-irradiation for Recurrent Glioma (PULSAR) | May 26, 2023 | May 26, 2028 |
| NCT01906385 | Recruiting | Phase 1/Phase 2 | Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT) | June 3, 2015 | January 2025 |
| NCT05569434 | Recruiting | Phase 1/Phase 2 | 68Ga-P16-093 PET/CT Imaging in Glioma Patients | November 28, 2021 | December 2024 |
| NCT03152318 | Recruiting | Phase 1 | A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 | July 18, 2017 | December 2025 |
| NCT05553041 | Recruiting | Early Phase 1 | 18F-Fluciclovine PET-MRI in High-grade Glioma | August 7, 2023 | December 2026 |
| NCT05538130 | Recruiting | Phase 1 | A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors | November 30, 2022 | September 28, 2028 |
| NCT01772771 | Recruiting | Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program | March 1, 2012 | March 1, 2033 | |
| NCT06102837 | Recruiting | Tumor Vaccines for Solid Tumors | October 2023 | October 2027 | |
| NCT05512403 | Recruiting | Phase 3 | Evaluation of Diagnostic Performances of 18F-FDOPA PET KInetics | June 13, 2023 | October 30, 2026 |
| NCT05859659 | Recruiting | Clinical, patHOlogical and Imaging Project of nEuro-oncology (HOPE) | January 1, 2022 | December 31, 2024 | |
| NCT06156150 | Recruiting | The Role of B7-H4 in Tumor Vaccine | November 26, 2023 | December 31, 2026 | |
| NCT05511324 | Recruiting | N/A | Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients | October 21, 2022 | August 31, 2024 |
| NCT05500391 | Recruiting | Phase 2 | Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring | February 28, 2024 | October 2029 |
| NCT05489783 | Recruiting | Glioma Developmental and HyperActive Ras Tumor (DHART) Board | July 29, 2022 | July 29, 2025 | |
| NCT05486923 | Recruiting | Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population | September 19, 2022 | June 1, 2024 | |
| NCT05464992 | Recruiting | N/A | Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI | December 28, 2022 | December 28, 2036 |
| NCT06161519 | Recruiting | Phase 1/Phase 2 | PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications | January 31, 2024 | November 14, 2033 |
| NCT05413304 | Recruiting | Phase 1 | Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis | April 7, 2023 | August 31, 2026 |
| NCT05386043 | Recruiting | Registering Genomics and Imaging of Tumors (ReGIT) | July 18, 2023 | July 17, 2027 | |
| NCT05383872 | Recruiting | N/A | Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors | August 8, 2022 | March 2025 |
| NCT05355701 | Recruiting | Phase 1 | A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. | July 5, 2022 | March 5, 2029 |
| NCT05352685 | Recruiting | N/A | Effects of Propofol on Auditory Event-related Potentials and Brain Functional Connectivity in Patients With Supratentorial Glioma | May 18, 2022 | September 30, 2024 |
| NCT05345002 | Recruiting | Phase 2 | All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma | November 16, 2022 | June 1, 2027 |
| NCT05310448 | Recruiting | N/A | Tumor Treating Fields for the Treatment of Brainstem Gliomas | May 11, 2022 | November 8, 2025 |
| NCT06454097 | Recruiting | N/A | Study on Radiogenomics Features Associated With Radiochemotherapy Sensitivity in Gliomas | January 23, 2024 | December 31, 2024 |
| NCT05303519 | Recruiting | Phase 2 | Safusidenib Phase 2 Study in IDH1 Mutant Glioma | June 5, 2023 | July 31, 2027 |
| NCT05274919 | Recruiting | Vascular Signature Mapping of Brain Tumor Genotypes | August 16, 2022 | May 2024 | |
| NCT05259605 | Recruiting | Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification | March 28, 2023 | December 15, 2026 | |
| NCT05188508 | Recruiting | Phase 2 | Pembrolizumab, Olaparib, and Temozolomide for People With Glioma | January 14, 2022 | January 2025 |
| NCT03684109 | Recruiting | N/A | Non-invasive Glioma Characterization Through Molecular Imaging | January 25, 2019 | January 2025 |
| NCT03687957 | Recruiting | Phase 1/Phase 2 | rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-severe Lymphopenic Gliomas Following Radiation and Temzolomide | January 4, 2019 | January 31, 2032 |
| NCT05182905 | Recruiting | Early Phase 1 | AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients | March 9, 2022 | January 2025 |
| NCT06234319 | Recruiting | CXCR4 PET/MRI Targeted Imaging for Grading Diagnosis, Molecular Typing, and Prognostic Evaluation of Brain Glioma | February 15, 2024 | December 31, 2025 | |
| NCT03718767 | Recruiting | Phase 2 | Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype | March 27, 2019 | February 27, 2026 |
| NCT03728673 | Recruiting | Phase 2 | A Study Utilizing Escitalopram in Glioma Patients | March 6, 2019 | August 2025 |
| NCT05076513 | Recruiting | Early Phase 1 | Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma | October 29, 2021 | February 2025 |
| NCT03739411 | Recruiting | Phase 1 | Hyperpolarized Imaging in Diagnosing Participants With Glioma | December 9, 2015 | June 30, 2024 |
| NCT05062772 | Recruiting | Brain Tumor Intraoperative Ultrasound Database | May 25, 2022 | December 30, 2023 | |
| NCT03796273 | Recruiting | Early Phase 1 | Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases | March 13, 2019 | September 2024 |
| NCT05049148 | Recruiting | N/A | Platelets Activation in Brain Neoplasms | October 20, 2022 | January 20, 2028 |
| NCT03865355 | Recruiting | Blood and Cerebrospinal Fluid Metabolomic Profile in Glioma Patients | March 13, 2019 | April 11, 2029 | |
| NCT02686229 | Recruiting | Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients With Low Grade Gliomas | November 15, 2015 | December 2036 | |
| NCT06294418 | Recruiting | N/A | FCI in Post-operative Low Grade Gliomas | February 15, 2024 | March 2025 |
| NCT06326411 | Recruiting | Phase 1 | A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors | April 9, 2024 | November 2029 |
| NCT05045027 | Recruiting | Early Phase 1 | Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma | September 1, 2021 | September 10, 2027 |
| NCT06412952 | Recruiting | Early Phase 1 | 68Ga-NOTA-RM26 PET/CT in Glioma Patients | October 1, 2022 | May 31, 2024 |
| NCT03952598 | Recruiting | N/A | Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy | October 16, 2019 | December 31, 2025 |
| NCT03964909 | Recruiting | N/A | Resting-State Functional MRI in Glioma Patients Before and After Surgery | April 24, 2017 | December 31, 2026 |
| NCT06327048 | Recruiting | N/A | Application of Cognitive Training Based on Remind Strategy in Glioma Patients With Cognitive Impairment | March 6, 2024 | December 1, 2024 |
| NCT03975959 | Recruiting | N/A | Memory Perception Assessment in Central/Non-central Nervous System Cancers | May 10, 2019 | October 30, 2024 |
| NCT04975139 | Recruiting | Cognitive Changes of IDH-mutant and IDH-wildtype Glioma Patients After Chemoradiotherapy With Radiation Dose to the Resting State Networks | September 2, 2020 | October 31, 2033 | |
| NCT03991832 | Recruiting | Phase 2 | Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors | December 31, 2019 | March 31, 2025 |
| NCT04943913 | Recruiting | Early Phase 1 | Study on TIL for the Treatment of Brain Glioma | May 6, 2021 | May 31, 2025 |
| NCT06330337 | Recruiting | Phase 3 | Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma | April 1, 2024 | December 31, 2027 |
| NCT04065776 | Recruiting | N/A | Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma | August 28, 2019 | July 2028 |
| NCT06348693 | Recruiting | Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness | April 19, 2017 | November 21, 2025 | |
| NCT06355908 | Recruiting | Phase 1 | IL13Rα2 CAR-T for Patients With r/r Glioma | March 21, 2024 | May 1, 2027 |
| NCT04931732 | Recruiting | The circTeloDIAG: Liquid Biopsy for Glioma Tumor | November 4, 2021 | November 2026 | |
| NCT04181684 | Recruiting | N/A | LITT Followed by Hypofractionated RT for Recurrent Gliomas | January 8, 2020 | December 2026 |
| NCT04185038 | Recruiting | Phase 1 | Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors | December 11, 2019 | May 2041 |
| NCT04186832 | Recruiting | N/A | Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy | September 28, 2020 | December 31, 2024 |
| NCT04916015 | Recruiting | Histomolecular Profiles of Gliomas in Children and Adolescent/Young Adults | June 1, 2021 | October 2023 | |
| NCT06363162 | Recruiting | N/A | Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery | December 1, 2022 | December 31, 2025 |
| NCT04215211 | Recruiting | MR Based Survival Prediction of Glioma Patients Using Artificial Intelligence | January 1, 2017 | June 1, 2027 | |
| NCT04215224 | Recruiting | Histopathology Images Based Survival Prediction of Glioma Patients Using Artificial Intelligence | January 1, 2017 | June 1, 2027 | |
| NCT04216537 | Recruiting | Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas | January 1, 2018 | June 1, 2025 | |
| NCT04217018 | Recruiting | MR Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence | January 1, 2017 | June 1, 2027 | |
| NCT04217044 | Recruiting | Histopathology Images Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence | January 1, 2017 | June 1, 2027 | |
| NCT04233788 | Recruiting | Metabolic Characterization of Space Occupying Lesions of the Brain | September 1, 2021 | August 31, 2023 | |
| NCT04274283 | Recruiting | Tessa Jowell BRAIN MATRIX - Platform Study | November 24, 2020 | March 1, 2027 | |
| NCT04309552 | Recruiting | Phase 1 | Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma | February 1, 2021 | December 2024 |
| NCT04373720 | Recruiting | N/A | MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas | March 20, 2020 | December 31, 2024 |
| NCT04772456 | Recruiting | Phase 1 | Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas | August 11, 2020 | December 31, 2026 |
| NCT04391595 | Recruiting | Early Phase 1 | LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients | July 8, 2020 | February 2025 |
| NCT06387979 | Recruiting | Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer Using Pathology Biopsies | October 26, 2020 | October 15, 2025 | |
| NCT06381726 | Recruiting | N/A | Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life | March 7, 2024 | February 28, 2028 |
| NCT04712214 | Recruiting | N/A | Use of Non-invasive Optical Analysis in Neurosurgery | March 28, 2021 | October 30, 2023 |
| NCT04699773 | Recruiting | N/A | LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138) | February 20, 2021 | December 2027 |
| NCT04687969 | Recruiting | Multimodal Machine Learning Characterization of Solid Tumors | October 23, 2022 | August 31, 2024 | |
| NCT04543201 | Recruiting | N/A | Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma | August 26, 2021 | July 31, 2026 |
| NCT05803057 | Recruiting | N/A | Accelerating Motor Recovering in Patients With SMA Syndrome After Glioma Surgery by Using nrTMS | April 1, 2023 | March 31, 2025 |
| NCT05916313 | Recruiting | Phase 1 | A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3 | December 13, 2023 | August 17, 2026 |
| NCT05773326 | Recruiting | Early Phase 1 | Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG | May 15, 2023 | April 30, 2026 |
| NCT05937776 | Recruiting | Developing a New Metabolic Imaging Approach (aMRI) for Evaluating Neurological Disease in Patients With Gliomas | December 11, 2023 | December 31, 2024 | |
| NCT05770544 | Recruiting | Phase 2/Phase 3 | DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. | June 2024 | October 2029 |
| NCT05768178 | Recruiting | Phase 2/Phase 3 | DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. | March 1, 2023 | October 2029 |
| NCT00870129 | Recruiting | N/A | Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors | March 2009 | September 2024 |
| NCT02372409 | Recruiting | Phase 2 | Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors | August 14, 2015 | August 31, 2030 |
| NCT02800486 | Recruiting | Phase 2 | Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA | May 2016 | May 2026 |
| NCT05964153 | Recruiting | N/A | Analysis of Circulating DNA in Blood Samples of Glioma-affected Patients | January 31, 2023 | January 31, 2024 |
| NCT05727605 | Recruiting | N/A | Neurocognition After Radiotherapy in CNS- and Skull-base Tumors | February 8, 2023 | February 1, 2027 |
| NCT05968053 | Recruiting | Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi) | September 25, 2023 | December 31, 2025 | |
| NCT05976490 | Recruiting | N/A | NeuroPathways Intervention for Brain Tumor Patients | October 16, 2023 | April 10, 2026 |
| NCT05979064 | Recruiting | N/A | Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) | April 4, 2023 | April 2027 |
| NCT05990244 | Recruiting | N/A | Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion | July 1, 2023 | July 1, 2025 |
| NCT05686798 | Recruiting | Phase 1 | Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma. | November 29, 2022 | October 2024 |
| NCT06011109 | Recruiting | Phase 1/Phase 2 | Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab | December 13, 2023 | January 31, 2025 |
| NCT05672043 | Recruiting | Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China | January 1, 2023 | December 31, 2032 | |
| NCT06018870 | Recruiting | MRI Contrast Clearance Analysis for Glioma Grading and Genotyping | June 1, 2023 | June 30, 2024 | |
| NCT05635435 | Recruiting | Immune and Inflammatory Indices in Peripheral Blood Predict Prognosis of Glioma and Correlate With Grades and Subtypes | October 13, 2006 | December 20, 2023 | |
| NCT05607407 | Recruiting | Phase 2 | Methimazole in Patients With Progressive Glioblastoma | January 30, 2023 | January 2026 |
| NCT00909558 | Suspended | Phase 1 | Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on Cancer | May 2009 | |
| NCT03095248 | Suspended | Phase 2 | Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors | May 8, 2017 | June 2025 |
| NCT03322813 | Suspended | N/A | ExAblate Blood Brain Barrier Disruption (BBBD) for Planned Surgery in Suspected Infiltrating Glioma | October 2023 | December 2024 |
| NCT03868943 | Suspended | Phase 2 | Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma | January 27, 2021 | July 2025 |
| NCT04222309 | Suspended | Phase 1 | Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) | January 6, 2020 | January 31, 2025 |
| NCT04667715 | Suspended | N/A | Safety and Effectiveness of Blood-Brain Barrier Disruption (BBBD) in Subjects With Suspected Infiltrating Glioma | December 2024 | June 2026 |
| NCT03352427 | Terminated | Phase 2 | Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations | December 6, 2017 | May 15, 2019 |
| NCT01502605 | Terminated | Phase 1 | Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas | September 2012 | June 2016 |
| NCT00360828 | Terminated | Phase 2 | Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas | February 2006 | October 2010 |
| NCT00108056 | Terminated | Phase 1 | Enzastaurin to Treat Recurrent Brain Tumor | April 7, 2005 | April 1, 2014 |
| NCT04541225 | Terminated | Phase 1 | Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors | December 8, 2020 | August 31, 2022 |
| NCT01044966 | Terminated | Phase 1/Phase 2 | A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma | September 2009 | September 2014 |
| NCT03335280 | Terminated | 68Ga-citrate PET/MR Imaging for Glioma | February 26, 2019 | April 24, 2020 | |
| NCT01263821 | Terminated | N/A | Image Guided Therapy in the Treatment of Gliomas | August 2009 | April 2014 |
| NCT04424966 | Terminated | Early Phase 1 | Infigratinib in Recurrent High-Grade Glioma Patients | July 21, 2020 | April 27, 2023 |
| NCT01351519 | Terminated | Phase 2 | A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors | May 2011 | January 2015 |
| NCT01229644 | Terminated | Phase 2 | Study of Crenolanib, a Selective and Potent Inhibitor of PDGFR, for the Treatment of Adult Gliomas | April 2011 | December 2012 |
| NCT01116661 | Terminated | Phase 2 | Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the Brain | August 2010 | February 28, 2019 |
| NCT02743078 | Terminated | Phase 2 | Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma | May 9, 2017 | October 15, 2019 |
| NCT02433392 | Terminated | Phase 1 | Study of Intraparenchymal Therapy as Adjunct Therapy in Patients With Recurrent, Resectable Glioblastoma Multiforme. | December 2011 | July 2015 |
| NCT03181581 | Terminated | Phase 2 | Improving Ultrasound Images in Brain Tumour Surgery With the Use of an Acoustic Coupling Fluid Mimicking Brain Tissue. | March 1, 2017 | December 31, 2018 |
| NCT04556929 | Terminated | N/A | Enhanced Detection in Glioma Excision | September 21, 2020 | November 3, 2021 |
| NCT02507232 | Terminated | Early Phase 1 | Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas | April 17, 2017 | July 27, 2020 |
| NCT03843814 | Terminated | N/A | Pilot Study Using Amide Proton Transfer Magnetic Resonance Imaging Distinguishing Glioma | August 2014 | December 13, 2017 |
| NCT02387840 | Terminated | N/A | Feasibility and Clinically Application of Magnetic Resonance Fingerprinting | March 2015 | July 31, 2019 |
| NCT03168919 | Terminated | N/A | Image-Based Quantitative Assessment of Acute Radiation-Induced Changes in Glioma | October 6, 2016 | June 12, 2018 |
| NCT03149575 | Terminated | Phase 3 | VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM | October 27, 2017 | August 31, 2019 |
| NCT02386241 | Terminated | Identification of Genomic Changes in Families Having Multiple Members With Tumors | March 2015 | July 31, 2019 | |
| NCT01902771 | Terminated | Phase 1 | Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors | September 3, 2013 | January 26, 2017 |
| NCT03436433 | Terminated | Phase 2 | Seizure Prophylaxis in Patients With Glioma or Brain Metastasis | January 31, 2019 | December 4, 2020 |
| NCT00880061 | Terminated | Phase 1 | An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma | April 7, 2009 | June 5, 2015 |
| NCT01986348 | Terminated | Phase 2 | Study Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Participants With Recurrent Gliomas | March 3, 2014 | January 23, 2020 |
| NCT05875935 | Terminated | N/A | Assessment of Awake Surgery With Electrocorticographic Recordings in the Management of Gliomas and Correlation With Imaging Data (ECoG) | December 17, 2021 | May 31, 2022 |
| NCT00815152 | Terminated | N/A | Coping With High Grade Glioma | December 2008 | October 2009 |
| NCT00389090 | Terminated | Phase 2 | A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma | October 2006 | February 2009 |
| NCT02029690 | Terminated | Phase 1 | Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin | April 23, 2014 | June 2020 |
| NCT00031538 | Terminated | Genetic Analysis of Brain Tumors | March 1, 2002 | April 29, 2015 | |
| NCT02783495 | Terminated | N/A | Feasibility And Efficacy Of An iPad-Based Cognitive Rehabilitation Program In Brain Tumor Patients | July 19, 2016 | January 17, 2019 |
| NCT00038389 | Terminated | Phase 1 | Study of Vioxx and Radiation Therapy for Brainstem Glioma | October 2001 | January 2005 |
| NCT02986815 | Terminated | N/A | [11C]Acetate PET in Patients With Glioma | January 24, 2017 | May 5, 2020 |
| NCT02371031 | Terminated | Phase 1 | FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas | March 2015 | July 2016 |
| NCT02279992 | Terminated | Early Phase 1 | Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases | March 27, 2012 | February 11, 2016 |
| NCT02481960 | Terminated | Phase 1/Phase 2 | Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma | February 21, 2012 | December 18, 2015 |
| NCT03593993 | Terminated | A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas | May 19, 2018 | July 7, 2023 | |
| NCT02924038 | Terminated | Phase 1 | A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG) | April 3, 2017 | December 31, 2022 |
| NCT02176720 | Terminated | Phase 1 | Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma | May 2014 | March 2016 |
| NCT02833701 | Terminated | Phase 1 | Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma | March 2016 | March 2019 |
| NCT03463733 | Unknown status | Phase 1 | Hydroxy-urea and Temozolomide in Patients With a Recurrent Malignant Brain Tumor (Glioblastoma) | March 2, 2018 | June 1, 2022 |
| NCT05459441 | Unknown status | Early Phase 1 | Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases | January 1, 2022 | December 31, 2023 |
| NCT01473485 | Unknown status | N/A | ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors | April 2011 | December 2022 |
| NCT03423992 | Unknown status | Phase 1 | Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas | March 2, 2018 | January 30, 2023 |
| NCT03407781 | Unknown status | Early Phase 1 | IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Lower Grade Glioma | January 1, 2016 | December 30, 2018 |
| NCT03390062 | Unknown status | Phase 2 | A Study of Apatinib in Recurrent or Recurrent High-grade Glioma | January 4, 2018 | August 1, 2020 |
| NCT01525459 | Unknown status | Gene Expression, Immunological Status and Metabolome in Glioma Patients | December 2010 | December 2012 | |
| NCT01567202 | Unknown status | Phase 2 | Study of DC Vaccination Against Glioblastoma | March 2012 | February 1, 2021 |
| NCT01579253 | Unknown status | Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients | April 2012 | ||
| NCT00660621 | Unknown status | Phase 2 | A Phase II Study Of Gliadel, Concomitant Temozolomide And Radiation, Followed By Dose Dense Therapy With Temozolomide Plus Bevacizumab For Newly Diagnosed Malignant High Grade Glioma | April 2008 | December 2010 |
| NCT01641003 | Unknown status | Isolation and Characterization of Cancer Stem Cells Using iFP Technique | July 2012 | June 2015 | |
| NCT00686387 | Unknown status | Establishment of a Brain and Spinal Tumor Tissue Bank | May 2008 | May 2013 | |
| NCT01798771 | Unknown status | N/A | Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery | March 2013 | February 2016 |
| NCT01801371 | Unknown status | Early Phase 1 | 68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma | October 2012 | December 2017 |
| NCT01801852 | Unknown status | N/A | Autologous Natural Killer T Cells Infusion for the Treatment of Cancer | January 2013 | June 2017 |
| NCT03102203 | Unknown status | Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Clinical Trial With Multimodality MR Imaging | June 8, 2016 | December 2018 | |
| NCT03058198 | Unknown status | N/A | The Research on 89Zr-ABT806 PET Imaging in High Grade Glioma | January 2017 | December 2020 |
| NCT00813787 | Unknown status | Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components | February 2009 | April 2015 | |
| NCT00045968 | Unknown status | Phase 3 | Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer | December 2006 | |
| NCT02119338 | Unknown status | N/A | 5-ALA in Recurrent Glioma | February 2014 | September 2017 |
| NCT02941302 | Unknown status | N/A | Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study | October 1, 2016 | December 31, 2018 |
| NCT00575796 | Unknown status | Phase 2 | Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs) | October 2007 | October 2019 |
| NCT04550663 | Unknown status | Phase 1 | NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors | September 25, 2020 | March 25, 2023 |
| NCT00122239 | Unknown status | A Study of Gene Polymorphisms and Normal Tissue Radiation Injury in Patients Treated for Breast, Prostate, Brain, Lung, and Head and Neck Cancers | January 2005 | February 2017 | |
| NCT02676687 | Unknown status | N/A | Supratotal Resection for Gliomas Within Noneloquent Areas | January 2016 | December 2018 |
| NCT04668508 | Unknown status | Phase 2 | Anlotinib to Malignant Brainstem Glioma | November 24, 2020 | January 1, 2023 |
| NCT04539431 | Unknown status | Glioma Brain Tumours - E12513 - SensiScreen Glioma | January 7, 2022 | December 31, 2022 | |
| NCT04689321 | Unknown status | Revision of the EORTC QLQ-BN20 Questionnaire | December 19, 2018 | January 1, 2024 | |
| NCT00330109 | Unknown status | N/A | Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology | June 2006 | December 2017 |
| NCT04706338 | Unknown status | N/A | Transcranial Magnetic Stimulation in the Rehabilitation of Postoperative Motor Dysfunction. | January 15, 2021 | January 1, 2022 |
| NCT04461002 | Unknown status | Evaluation of the Correlation Between Molecular Phenotype and Radiological Signature (by PET-scanner and MRI) of Incident WHO II and III Grade Gliomas. | September 30, 2019 | December 31, 2021 | |
| NCT04425798 | Unknown status | Connectivity Alterations After Levetiracetam Application | May 25, 2022 | September 30, 2022 | |
| NCT04738110 | Unknown status | Post-operative Imaging in High Grade Glioma: is Management Influenced? | July 20, 2020 | December 16, 2022 | |
| NCT04407039 | Unknown status | Establishment and Evaluation of Multimodal Image Recognition System of Glioma Based on Deep Learning | December 30, 2021 | December 30, 2022 | |
| NCT04388033 | Unknown status | Phase 1/Phase 2 | Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients. | December 2020 | December 2023 |
| NCT04781764 | Unknown status | The Study of Microglia/Macrophages Involved Dynamic Evolution of Glioma Microenvironment and the Function and Visualization of Targeted Molecules of Glioma | November 9, 2020 | December 31, 2022 | |
| NCT04792437 | Unknown status | Research on Precise Immune Prevention and Treatment of Glioma Based on Multi-omics Sequencing Data | March 10, 2021 | September 30, 2022 | |
| NCT04220424 | Unknown status | Glioma Patients Registry Based on Radiological, Histopathological and Genetic Analysis | November 1, 2018 | March 1, 2022 | |
| NCT04902586 | Unknown status | N/A | Effect of Radiotherapy Concurrent of TTFields in Patients With Glioblastoma | June 19, 2021 | July 19, 2022 |
| NCT04194593 | Unknown status | Biomarker-based Algorithm for Diagnosis of Glioma | December 1, 2018 | March 1, 2021 | |
| NCT04122521 | Unknown status | Radiogenomic and Prognosis Analysis in Glioma | January 12, 2020 | February 2021 | |
| NCT04953468 | Unknown status | Expression of ANXA2 in the Extracellular Space in the Microenvironment of Periumoral Edema Promotes Glioma Invasion | February 19, 2021 | August 1, 2023 | |
| NCT04970615 | Unknown status | Educating Brain Tumor Patients Using Patient-specific Actual-size Three-dimensional Printed Models | May 15, 2021 | December 15, 2023 | |
| NCT05019196 | Unknown status | fMRI Study of Functional Reorganization in Glioma Patients | September 1, 2021 | December 31, 2022 | |
| NCT05025969 | Unknown status | Evaluation of the Incidence of NTRK Gene Fusion in Adult Brain Tumours | September 2021 | February 2022 | |
| NCT03971812 | Unknown status | Organoids Derived From Induced-Pluripotent Stem Cells (iPS) From Patients With High Grade Astrocytoma | June 7, 2019 | December 6, 2020 | |
| NCT03941626 | Unknown status | Phase 1/Phase 2 | Autologous CAR-T/TCR-T Cell Immunotherapy for Solid Malignancies | September 1, 2019 | December 1, 2021 |
| NCT03741244 | Unknown status | Phase 2 | TMZ Plus Apatinib in Newly Diagnosed High-grade Glioma：RCT | May 6, 2019 | February 2023 |
| NCT05133154 | Unknown status | N/A | LIQUID BIOPSY IN Low-grade Glioma Patients | January 5, 2022 | April 2023 |
| NCT03716986 | Unknown status | N/A | Multimodal Imaging of Hypoxia in Gliomas | November 1, 2018 | November 1, 2019 |
| NCT05143775 | Unknown status | N/A | Strategic Intervention on Preserving Language Function During Awake Craniotomy | December 2021 | June 2024 |
| NCT05143788 | Unknown status | N/A | Strategic Intervention on Preserving Motor Function During Awake Craniotomy | December 2021 | December 2023 |
| NCT03690570 | Unknown status | Long Term Follow up of Patients Under 5 Years of Age With High Grade Glioma Diagnosed in France Between 1990 and 2015 | May 9, 2018 | May 9, 2019 | |
| NCT03641391 | Unknown status | N/A | Awake Intraoperative Language Mapping and Chinese Probabilistic Map Construction | September 1, 2018 | December 1, 2023 |
| NCT05188534 | Unknown status | ZOOMit-fMRI Identifies Language Functional Cortex | February 1, 2022 | December 31, 2022 | |
| NCT03638206 | Unknown status | Phase 1/Phase 2 | Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies | March 1, 2018 | March 1, 2023 |
| NCT00418899 | Unknown status | Gliogene: Brain Tumor Linkage Study | February 12, 2004 | September 1, 2022 | |
| NCT03531333 | Unknown status | N/A | Intraoperative Ultrasound Guided Glioma Surgery; a Randomised, Controlled Trial. | November 1, 2016 | August 1, 2020 |
| NCT00454935 | Unknown status | Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy | April 2007 | October 2008 | |
| NCT00256425 | Unknown status | Phase 3 | Cognitive Rehabilitation of Glioma Patients | October 2003 | September 2007 |
| NCT00660283 | Unknown status | Phase 2 | A Phase II Study of Gliadel, Concomitant Temozolomide and Radiation, Followed By Dose Dense Therapy With Temozolomide For Newly Diagnosed Malignant High Grade Glioma | January 2009 | December 2010 |
| NCT01403311 | Unknown status | Phase 2 | A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain | October 2010 | March 2015 |
| NCT02272452 | Unknown status | Assistance in Neurosurgery (ExtempoRMN) | October 2014 | ||
| NCT02795364 | Unknown status | N/A | Study About the Validity of MRS-guided Resection on Prognosis High-grade Glioma Gliomas | June 2016 | May 2018 |
| NCT02327442 | Unknown status | 68Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and Applications in Glioma Patients or Breast Cancer Patients | June 2014 | December 2015 | |
| NCT02345824 | Unknown status | Phase 1 | Early-Phase Study to Assess Inhibitor Ribociclib in Patients With Recurrent Glioblastoma or Anaplastic Glioma | March 2016 | January 2020 |
| NCT02363075 | Unknown status | Phase 3 | Dexamfetamine Sulphate in Patients With Glioma Suffering From Severe Asthenia | April 2013 | January 2018 |
| NCT02402075 | Unknown status | Spinal Motor Evoked Potentials in Brain Surgery | January 2014 | December 2015 | |
| NCT02771301 | Unknown status | N/A | Safety and Efficacy of IDH1R132H-DC Vaccine in Gliomas | February 2016 | January 2019 |
| NCT02520882 | Unknown status | Early Phase 1 | 68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas | January 2015 | December 2017 |
| NCT00977327 | Unknown status | N/A | Comparison of Neuro-navigational Systems for Resection-Control of Brain Tumors | September 2009 | |
| NCT02597335 | Unknown status | N/A | Non Invasive Detection of IDH1/2 Mutation in Gliomas | April 2015 | April 2018 |
| NCT02622620 | Unknown status | Study on Neuroepithelial Tumor Grading and Pseudoprogression After Glioma Therapy Using Advanced Functional MRI Techniques | July 2016 | November 2018 | |
| NCT02652897 | Unknown status | Hemostasis Alterations in Neurosurgical Patients | May 2016 | March 2019 | |
| NCT01778088 | Withdrawn | Phase 2 | Open-Label Study of I-131-CLR1404 in Subjects With Recurrent Glioma | May 2014 | January 2015 |
| NCT04051047 | Withdrawn | Early Phase 1 | Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma | November 30, 2019 | December 2021 |
| NCT02754362 | Withdrawn | Phase 2 | A Toll-like Receptor Agonist as an Adjuvant to Tumor Associated Antigens (TAA) Mixed With Montanide ISA-51 VG With Bevacizumab for Patients With Recurrent Glioblastoma | November 2016 | June 2019 |
| NCT03193463 | Withdrawn | Early Phase 1 | Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy | November 3, 2017 | November 19, 2018 |
| NCT01182883 | Withdrawn | Phase 1 | A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors | July 28, 2010 | April 4, 2012 |
| NCT05373381 | Withdrawn | N/A | The KetoGlioma (Ketogenic Glioma) Study | May 18, 2022 | May 18, 2022 |
| NCT00985036 | Withdrawn | Vascular Endothelial Growth Factor (VEGF) Levels in Brain Tumor Patients | September 2009 | January 2012 | |
| NCT02919332 | Withdrawn | Delayed 18F-FDG PET/CT in Improving Visualization of Brain Tumors in Patients With Glioblastoma | June 8, 2016 | December 12, 2018 | |
| NCT03632317 | Withdrawn | Phase 2 | A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas | October 2019 | October 2025 |
| NCT05061251 | Withdrawn | Early Phase 1 | Surgical Window of Opportunity Study of Orally Administered BAY 2402234 in Recurrent Glioma | December 1, 2021 | December 1, 2023 |
| NCT05672082 | Withdrawn | N/A | Contribution of [18F]DPA-714 PET for Grading and Exploration of the Inflammatory Microenvironment of Glioma. | October 1, 2023 | April 1, 2025 |
| NCT02713984 | Withdrawn | Phase 1/Phase 2 | A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer | March 2016 | July 2019 |
| NCT03935269 | Withdrawn | N/A | Cereset for Caregivers | March 2024 | September 2024 |
| NCT02689336 | Withdrawn | Phase 2 | Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors | August 6, 2016 | May 31, 2020 |
| NCT02977689 | Withdrawn | Phase 2 | Trial of IDH305 in IDH1 Mutant Grade II or III Glioma | April 2018 | April 2020 |
| NCT02987010 | Withdrawn | Phase 2 | Phase 2 Study of IDH305 in Low Grade Gliomas | January 2017 | January 2019 |
| NCT01861990 | Withdrawn | Phase 1 | Valproic Acid in Childhood Progressive Brain Tumors | May 2013 | December 2013 |
| NCT00734864 | Withdrawn | Phase 1 | Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma | June 2009 | June 2012 |
| NCT03990597 | Withdrawn | Phase 1 | StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord | August 19, 2019 | November 24, 2020 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0009733
- OMIM Phenotype Series Number (OMIM)
- PS137800
- MeSH unique ID (MeSH (Medical Subject Headings))
- D005910