Liver neoplasms

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Information
Disease name
Liver neoplasms
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03651154 Active, not recruiting N/A Hypovolemic Phlebotomy to Reduce Blood Transfusions in Major Hepatic Resections September 28, 2018 March 2024
NCT06278701 Active, not recruiting N/A The Effect of Late-evening Snacks on Patients With Primary Hepatocellular Carcinoma After Hepatectomy November 1, 2023 July 30, 2025
NCT04682847 Active, not recruiting Radiotherapy With Iron Oxide Nanoparticles (SPION) on MR-Linac for Primary & Metastatic Hepatic Cancers November 19, 2020 December 31, 2024
NCT02501980 Active, not recruiting Hepatocellular Cancer (HCC) Screening in Zhongshan City January 2012 December 2024
NCT04572633 Active, not recruiting N/A The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy January 27, 2021 July 2026
NCT04573881 Active, not recruiting N/A The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK) June 4, 2021 July 2026
NCT00122876 Completed Phase 1/Phase 2 Tumor Ablation With Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC) April 2005 October 2006
NCT00143403 Completed Phase 3 Comparing Irinotecan and 5 FU/FA To 5-FU/FA After Resection Of Liver Metastases For Colorectal Cancer December 2001 September 2009
NCT00149396 Completed Phase 1/Phase 2 Safety & Efficacy of NV1020 in Colorectal Cancer Metastatic to the Liver July 2004 December 2008
NCT00152906 Completed Phase 1/Phase 2 Stereotactic Radiotherapy (SRT) Liver (COLD 1) July 2003 July 10, 2020
NCT00178243 Completed Phase 1/Phase 2 Feasibility of Treatment of Cancer Involving the Liver With High Dose Radiation
NCT00222664 Completed Phase 4 Qidong Hepatitis B Intervention Study September 1983 December 2004
NCT00247676 Completed Phase 2 An International Phase 2 Study Of SU011248 In Patients With Inoperable Liver Cancer February 2006 February 2009
NCT00327652 Completed Phase 1 Study of Safety and Tolerability of Intravenous CRS-100 in Adults With Carcinoma and Liver Metastases October 2006
NCT00341484 Completed Genetic Susceptibility to Oncogenic Viruses June 1, 1998 June 5, 2007
NCT00355355 Completed Phase 3 A Phase 3 Study of Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC) July 2006 September 2012
NCT00392366 Completed N/A Laser Interstitial Thermal Therapy Under "Real Time" MRI Guidance for "Minimal Invasive" Treatment of Liver Metastasis July 2006 July 2008
NCT00441376 Completed Phase 1 A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver February 2007 December 2009
NCT01033240 Completed Phase 2 CS1008- in Combination With Sorafenib Compared to Sorafenib Alone in Subjects With Advanced Liver Cancer July 9, 2010 September 9, 2013
NCT00041808 Completed Phase 1/Phase 2 Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver July 2001 April 2003
NCT00068068 Completed Phase 2 Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases October 2003
NCT00081848 Completed Phase 1 Vaccine Therapy and Radiation to Liver Metastasis in Patients With CEA-Positive Solid Tumors April 20, 2004 August 23, 2007
NCT00083785 Completed Phase 2 Study of the Litx™ System Combined With Chemotherapy in Patients With Colorectal Liver Metastases May 2004
NCT00094003 Completed Phase 1 Study of NS-9 in Patients With Liver Metastases September 2002
NCT00493883 Completed Phase 1/Phase 2 Use of TheraSphere® Yttrium-90 Glass Microspheres for Primary and Metastatic Liver Tumors December 2006 December 2011
NCT00584402 Completed N/A Contrast Sonography for Evaluation of Liver Tumors Prior to Radiofrequency Ablation April 2007 March 2009
NCT00681499 Completed Quality of Life After Liver Resection February 2008 January 2014
NCT00788697 Completed Phase 3 SonoVue®-Enhanced Ultrasound Versus Unenhanced US for Focal Liver Lesion Characterization September 2009 July 2013
NCT00829413 Completed Phase 3 SonoVue®-Enhanced Ultrasound (US) Versus Unenhanced US for Focal Liver Lesion Characterization June 2010 July 2013
NCT00922181 Completed N/A Single-probe Microwave Ablation (MWA) of Metastatic Liver Cancer August 2008 April 2009
NCT00001587 Completed Phase 1 A Phase I Study of Isolated Hepatic Portal and Arterial Perfusion (IHP) With Escalating Dose Melphalan for Primary or Metastatic Unresectable Cancers of the Liver September 1997 March 2001
NCT01043523 Completed Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions. December 2009 April 2013
NCT01099631 Completed Phase 1 IL-2 Expressing, Attenuated Salmonella Typhimurium in Unresectable Hepatic Spread April 2010 June 2014
NCT01177007 Completed Phase 2 Intra-arterial Y-90 TheraSpheres for Hepatic Metastases From Solid Tumors September 2010 August 2014
NCT01218854 Completed Phase 1 A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy March 20, 2012 November 16, 2016
NCT01306058 Completed Phase 1/Phase 2 Sorafenib and TRC105 in Hepatocellular Cancer February 11, 2011 June 9, 2017
NCT01307878 Completed Phase 3 New Adjuvant Chemotherapy of Asymptomatic Resectable Primary Lesion With Unresectable Liver-limited Metastases June 2012 June 2021
NCT01394497 Completed Phase 2 Use of N-Acetylcysteine During Liver Procurement December 2006 July 2009
NCT01528878 Completed N/A Safety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastases April 2009 January 28, 2016
NCT01612325 Completed Phase 2 Radioactive Holmium Microspheres for the Treatment of Unresectable Liver Metastases May 2012 August 2015
NCT01738217 Completed Phase 1/Phase 2 Assessment of Indocyanine Green as a Near-Infrared Fluorescent Contrast Agent for Image-guided Liver Surgery April 2013 June 2015
NCT01785212 Completed N/A The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the Liver March 2013 April 2015
NCT01895673 Completed PET-MRI After Radiofrequency Ablation (RFA) or Microwave Ablation (MWA) June 2013 June 2016
NCT02018107 Completed N/A PET/CT-Assessment of Liver Tumor Ablation January 2014 February 16, 2019
NCT02094625 Completed Phase 1 NAC to Prevent Cisplatin-induced Hearing Loss March 2016 August 2021
NCT02312817 Completed N/A RCT of Screening Strategies Among Patients at High Risk for Developing HCC in a Safety-net Health System December 2014 August 2017
NCT02338778 Completed Phase 1/Phase 2 Safety and Efficacy Study of Mix Vaccine in Hepatocyte Carcinoma Patient January 2015 August 2015
NCT02404909 Completed Inferior Vena Cava Index in Patients Undergoing Liver Resection January 2005 December 2014
NCT02454686 Completed Fibroscan Predicts Complications After Hepatectomy February 2012 May 2015
NCT02456285 Completed Colorectal Cancer With Liver-limited Synchronous Metastases: an Inception Cohort Study of Standardised Care Pathways May 20, 2015 April 30, 2017
NCT02489838 Completed Lung Dose in Patients Treated With Yttrium-90 for Hepatocellular Carcinoma February 3, 2012 August 7, 2019
NCT02548910 Completed N/A Phlebotomy to Prevent Blood Loss in Major Hepatic Resections April 2016 March 2018
NCT02582918 Completed N/A Texas Hepatocellular Carcinoma Consortium (THCCC) Project 5 March 26, 2018 June 30, 2022
NCT02649868 Completed Phase 2 LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment With Transarterial Embolization (TAE) Alone or Combined With Thermal Ablation January 12, 2016 December 2, 2023
NCT02760537 Completed N/A Lay Health Worker Model to Reduce Liver Cancer Disparities in Asian Americans April 2013 October 2014
NCT02834780 Completed Phase 1 Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma December 28, 2016 February 23, 2022
NCT03045952 Completed N/A Percutaneous Microwave Ablation Under Ultrasound Guidance for Liver Cancer: a Multicenter Analysis January 2013 December 2020
NCT03289273 Completed Observational Study to Evaluate, Under Real-world Practice Conditions, the Safety and Effectiveness of Regorafenib in Patients Diagnosed With Unresectable Hepatocellular Carcinoma (uHCC) September 13, 2017 June 21, 2022
NCT03338543 Completed N/A PENS or TENS for Pain in Liver Cancer November 1, 2017 August 30, 2019
NCT03405909 Completed Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study April 21, 2018 April 6, 2019
NCT03577067 Completed Complicated Outcome Prediction After Liver Resection February 2015 March 2017
NCT03630978 Completed Impact of Sarcopenia on Postoperative Outcomes of Patients Undergoing Liver Resection July 1, 2018 December 20, 2019
NCT03888859 Completed Early Phase 1 ET1402L1-ARTEMIS™2 T Cells in Alpha Fetoprotein (AFP) Expressing Hepatocellular Carcinoma December 6, 2017 December 8, 2020
NCT04246125 Completed Patient Skin Dose in Interventional Radiology October 13, 2020 June 7, 2022
NCT04618367 Completed N/A HAIC Combined With Lenvatinib and Sintilimab for Hepatocellular Carcinoma With PVTT January 1, 2021 December 30, 2022
NCT04618692 Completed N/A Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation December 2, 2020 March 30, 2023
NCT05164406 Completed Impact of Blood Salvage Therapy on Outcomes After Oncologic Liver Surgery January 1, 2018 February 28, 2021
NCT05225207 Completed A Study of Lenvima (Lenvatinib) in Korean Unresectable Hepatocellular Carcinoma (uHCC) Participants May 28, 2019 January 31, 2022
NCT05261113 Completed CE-IOUS Impact on Surgical Strategy of Liver Tumours and Liver Metastases January 1, 2017 June 30, 2021
NCT06271109 Enrolling by invitation Short Term Surgical Outcomes of Anatomical Versus Non Anatomical Laparoscopic Liver Resection for Liver Tumors December 1, 2021 June 1, 2025
NCT02960620 No longer available Therasphere for Unresectable Primary or Secondary Liver Neoplasia
NCT06050200 Not yet recruiting N/A TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery May 2024 May 2029
NCT06261814 Not yet recruiting Phase 2 Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors August 31, 2024 January 1, 2028
NCT04641923 Not yet recruiting N/A The Efficacy of a Topical Anti-adhesive Film for Decreasing Perihepatic Adhesions in Repeat Hepatic Surgery November 2022 June 2025
NCT04962958 Not yet recruiting Phase 2 Hepatic Artery Infusion Chemotherapy Plus Donafenib in Patients With Hepatocellular Carcinoma After Surgery July 1, 2023 August 2024
NCT04825470 Not yet recruiting N/A Liver Transplantation for Unresectable GIST Liver Metastases May 2022 December 2025
NCT05817994 Not yet recruiting Endoscopic Ultrasound Guided Liver Biopsy and Portal Pressure Registry April 2023 July 2023
NCT04954521 Recruiting Anlotinib for Hepatocellular Carcinoma June 30, 2021 July 5, 2024
NCT05531864 Recruiting N/A Ultrasound-guided Continuous Low Serratus Anterior Plane Block in Hepatocellular Carcinoma Surgery January 1, 2021 February 29, 2024
NCT03715517 Recruiting N/A Spinal Anesthesia For Enhanced Recovery After Liver Surgery October 4, 2018 January 2026
NCT04008797 Recruiting Phase 1 A Study of E7386 in Combination With Other Anticancer Drug in Participants With Solid Tumor July 11, 2019 March 15, 2027
NCT04075305 Recruiting The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study February 1, 2019 May 1, 2025
NCT06059885 Recruiting Phase 2 Tislelizumab Plus TKI as Adjuvant Therapy Versus Active Surveillance in Patients With HCC December 22, 2021 December 20, 2025
NCT04634357 Recruiting Phase 1/Phase 2 ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma July 19, 2022 January 31, 2028
NCT05977764 Recruiting N/A Multimodal Ultrasound and Focal Liver Lesions (FLLs) March 13, 2020 December 30, 2024
NCT05931068 Recruiting Perioperative Energy Expenditure in Major Liver Resection May 1, 2023 August 31, 2024
NCT00051532 Terminated N/A Seocalcitol Versus Placebo in Advanced Hepatocellular Carcinoma September 1999 May 2004
NCT01098422 Terminated N/A A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver January 2010 February 2015
NCT00106054 Terminated Phase 2 Neoadjuvant Colorectal Cancer With Unresectable Liver Metastases January 2006 September 2006
NCT00152607 Terminated Phase 4 Orthotopic Liver Transplantation Using a Living Donor April 2000 September 2006
NCT03685591 Terminated Phase 1 PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors October 4, 2018 March 30, 2022
NCT02900248 Terminated CureOne Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated by Physician Choice October 2, 2017 March 29, 2019
NCT02958163 Terminated Phase 2 Clinical Trial Comparing TACE With TACE + SABR in Stage BCLC B HCC (HepSTAR) February 20, 2017 October 17, 2017
NCT01525069 Terminated Phase 1 Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma April 3, 2012 August 2, 2022
NCT00470340 Terminated Phase 3 Chemotherapy or Not, Following Complete Treatment of Hepatic Cancer in Cirrhotic Patients June 2007 November 2008
NCT00051545 Terminated Phase 3 Seocalcitol Versus Placebo in the Adjuvant Treatment of Hepatocellular Carcinoma November 1999 June 2004
NCT00145665 Terminated Phase 1/Phase 2 The Role of Fluorothymidine Positron Emission Tomography (FLT-PET) in Proliferation of Colorectal Liver Metastases January 2005 December 2012
NCT01744054 Terminated Phase 1 Microsphere Localization Using PET/MRI or PET/CT in Patients Following Radioembolization October 25, 2012 April 3, 2017
NCT01862718 Terminated Phase 1 Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms November 19, 2013 November 5, 2019
NCT02470533 Terminated Phase 2 Transarterial Chemoembolization Versus Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma April 30, 2015 April 30, 2020
NCT00763776 Terminated N/A Parenchyma Resection of Cirrhotic Liver by the Clamp Crushing Technique and the Ultrasonic Dissector July 2008 September 2010
NCT03349255 Terminated Phase 1 Clinical Study of ET1402L1-CAR T Cells in AFP Expressing Hepatocellular Carcinoma October 6, 2017 January 10, 2019
NCT01009593 Terminated Phase 3 Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC) January 2010 July 2012
NCT01924741 Unknown status Registry of Major Liver Resections Including ALPPS and Other Liver Resections in Two Stages August 2013 December 2016
NCT02405416 Unknown status N/A Infrahepatic Inferior Vena Cava Clamping Versus Selective Hepatic Vascular Exclusion Involving the Portal Triad Clamping March 2015 June 2017
NCT02413437 Unknown status N/A A Trial on Contrast-enhanced Ultrasound Versus Conventional Ultrasound Guided Biopsy of Liver Neoplasms April 2015 December 2017
NCT04627363 Unknown status Phase 2 HAIC Combined With Bevacizumab and Toripalimab for Advanced Hepatocellular Carcinama January 1, 2021 June 30, 2023
NCT00356161 Unknown status Phase 2 HAI Via Interventionally Implanted Port Catheter Systems April 2002 April 2008
NCT02521129 Unknown status Phase 1/Phase 2 A New Track Ablation Device for Liver Biopsy: A Feasibility Study September 2015 February 2016
NCT02647047 Unknown status N/A Spinal Versus Epidural Analgesia in Laparotomic Liver Surgery January 2016 December 2016
NCT02715089 Unknown status Precise Treatment in Hepatobiliary Cancers (PTHBC) December 2015 December 2018
NCT02729493 Unknown status N/A Study Evaluating the Efficacy and Safety With CAR-T for Liver Cancer November 14, 2015 November 2019
NCT02758977 Unknown status N/A Associating Liver Partition With Portal Vein Ligation for Staged Hepatectomy (ALPPS) vs. Two-Stage Hepatectomy (TSH) for Marginally Resectable Colorectal Liver Metastases (CRLM) May 2016
NCT02969096 Unknown status Phase 2 Clinical Study of Targeted Cryoablation Therapy in the Treatment of Hepatic Carcinoma October 2016 December 2018
NCT05068180 Unknown status Phase 4 Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients October 5, 2021 April 10, 2022
NCT03143140 Unknown status N/A The Effect of Percutaneous Radiofrequency Ablation of Feeding Arterial for Hepatocellular Carcinoma May 22, 2014 December 1, 2018
NCT00659022 Unknown status Phase 2 Neo-adjuvant Therapy and the Effect on Synchronous Metastatic Growth July 2008 April 2014
NCT03223142 Unknown status N/A Standardization of Multi-modal Tumor Ablation Therapy System July 2017 July 2020
NCT03585166 Unknown status Nursing Fro Laparoscopic vs. Open Hepatectomy October 1, 2017 October 31, 2023
NCT03592550 Unknown status The eValuation of Image Guidance of Stereotactic Body Radiotherapy Using Ultrasound: Assessment in Liver September 2018 December 2019
NCT01214343 Unknown status Phase 3 Comparing Efficacy of Sorafenib Versus Sorafenib in Combination With Low-dose FP in Patients With Advanced HCC October 2010 September 2013
NCT01423708 Unknown status Phase 2 Everolimus in de Novo Liver Transplantation: a Multicentre Randomized Study February 2010 January 2014
NCT01436721 Unknown status Phase 2/Phase 3 Use of an Oxidized Regenerated Cellulose After Hepatic Surgery August 2011 December 2011
NCT01465425 Unknown status Extracolonic Findings on Computed Tomography (CT) Colonography September 2011 December 2019
NCT01556815 Unknown status Phase 2 Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma May 2012 May 2015
NCT01564810 Unknown status Phase 4 Cetuximab in Combination With Chemotherapy for the Treatment of Metastatic Colorectal Cancer September 2006 September 2015
NCT01567631 Unknown status N/A Classical Procedure Versus Intrahepatic Glisson's Approach January 2012 December 2017
NCT03965546 Unknown status Early Phase 1 ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer May 30, 2019 June 2022
NCT04218253 Unknown status N/A Clinical Application of Nutrition Support Package Before Hepatectomy October 1, 2019 June 30, 2022
NCT02363218 Unknown status Phase 2 Study on Effectiveness and Safety of Hepatocellular Carcinoma Patients Treated With CyberKnife May 2014 December 2017
NCT01972503 Unknown status Phase 4 Intraoperative Intraportal Chemotherapy Combined With Adjuvant Chemotherapy for Stage II and III Colorectal Cancer June 2008 September 2015
NCT02036008 Unknown status N/A Gadofosveset Trisodium (Ablavar, Gdfos) in Distinguishing Hemangiomas and Metastases: A Prospective Trial August 2013 July 2015
NCT04518852 Unknown status Phase 2 TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC September 14, 2020 January 31, 2023
NCT02168608 Unknown status N/A Remote Ischemia Precondition (RIPC) for Hepatic Protection in Patients Undergoing Hepatectomy September 2014 June 2016
NCT02192671 Unknown status Phase 3 HR Versus RFA for HCC in Patients With PHT May 2015 December 2022
NCT01711450 Withdrawn N/A Success of Paravertebral Blocks in Analgesia for Interventional Hepatic Procedures December 2012 June 2013
NCT01281943 Withdrawn Phase 2 Study of Pegylated Liposomal Doxorubicin and Temsirolimus in Patients With Advanced Hepatocellular Cancer June 2011 May 2014
MeSH unique ID (MeSH (Medical Subject Headings))
D008113