pemphigus
Information
- Disease name
- pemphigus
- Disease ID
- DOID:9182
- Description
- "An autoimmune disease of skin and connective tissue that is characterized by blistering of the outer layer of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals), causing lesions and blisters that are easily ruptured." [url:https\://en.wikipedia.org/wiki/Pemphigus, url:https\://medlineplus.gov/pemphigus.html, url:https\://rarediseases.org/rare-diseases/pemphigus/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04400994 | Active, not recruiting | Phase 2 | IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus | June 20, 2020 | December 31, 2025 |
| NCT00127764 | Completed | Phase 2/Phase 3 | European Trial of Adjuvant Oral Glucocorticoid Pulse Therapy in Pemphigus | January 2001 | April 2005 |
| NCT00213512 | Completed | Phase 2/Phase 3 | Effect of Anti CD20 in Pemphigus Desease | June 2003 | October 2008 |
| NCT00010413 | Completed | Phase 2 | Phase II Study of High-Dose Cyclophosphamide in Patients With Refractory Pemphigus | April 1999 | |
| NCT00283712 | Completed | Phase 2 | Use of Infliximab for the Treatment of Pemphigus Vulgaris | March 2006 | March 2011 |
| NCT00656656 | Completed | Phase 2 | Immunoadsorption, Dexamethasone Pulse Therapy and Rituximab for Pemphigus | January 2008 | July 2011 |
| NCT00960713 | Completed | The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders | June 2009 | January 2012 | |
| NCT01299857 | Completed | Phase 3 | Long-term Clinical and Biological Evaluation of Patients With Severe Forms of Pemphigus Treated by Rituximab | June 2011 | June 2012 |
| NCT06454357 | Not yet recruiting | Phase 2/Phase 3 | A Clinical Study of B007 in the Treatment of Pemphigus. | June 30, 2024 | December 31, 2026 |
| NCT05898308 | Not yet recruiting | Phase 4 | Comparison of a Personalized Maintenance Therapy With the Standard Treatment in Pemphigus | September 1, 2023 | July 1, 2031 |
| NCT06285435 | Not yet recruiting | Coagulation Activation in Patients With Pemphigus | March 1, 2024 | February 2026 | |
| NCT05954416 | Recruiting | FARD (RaDiCo Cohort) (RaDiCo-FARD) | March 7, 2018 | March 7, 2027 | |
| NCT05534776 | Recruiting | Validation of 5-Point Investigator Global Assessments for Pemphigus | September 21, 2022 | August 30, 2023 | |
| NCT03075904 | Terminated | Phase 1/Phase 2 | A Safety and Dose-Finding Study of SYNT001 in Subjects With Pemphigus (Vulgaris or Foliaceus) | July 18, 2017 | January 16, 2019 |
| NCT03762265 | Terminated | Phase 3 | A Study of PRN1008 in Patients With Pemphigus | January 8, 2019 | December 17, 2021 |
| NCT01313923 | Terminated | Early Phase 1 | Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis Pemphigus | February 2011 | October 2014 |
| NCT01559155 | Terminated | Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous Pemphigoid | November 5, 2013 | June 9, 2015 | |
| NCT02613910 | Terminated | Phase 3 | Long-Term Extension Study of Ofatumumab in Subjects With Pemphigus Vulgaris | December 23, 2015 | March 23, 2016 |
| NCT00278642 | Terminated | Phase 1 | Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders | September 2002 | September 2011 |
| NCT02365675 | Unknown status | N/A | Wound Dressings for Pemphigus and Pemphigoid | January 2015 | June 2016 |
| NCT01974518 | Unknown status | Phase 3 | Comparative Study of Rituximab Versus Combination of Rituximab and Intravenous Cyclophosphamide in Severe Pemphigus | November 2013 | June 2015 |
| NCT02237313 | Unknown status | N/A | Identification of Vulnerability Factors in the Course of Pemphigus Patients | July 2015 | November 2018 |
| NCT01338103 | Unknown status | N/A | Treatment of Pemphigus Patients With Rituximab 1000mgX2 and Assessment of Immune Status Via Cylex | January 2010 | June 2012 |
| NCT05284929 | Unknown status | Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population | May 17, 2017 | March 17, 2023 |
- Disase is a (Disease Ontology)
- DOID:0060039
- Cross Reference ID (Disease Ontology)
- GARD:7352
- Cross Reference ID (Disease Ontology)
- ICD10CM:L10
- Cross Reference ID (Disease Ontology)
- ICD9CM:694.4
- Cross Reference ID (Disease Ontology)
- MESH:D010392
- Cross Reference ID (Disease Ontology)
- NCI:C34909
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:156355008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0030807
- ICD10 preferred id (Insert disease from ICD10)
- D0009653
- ICD10 class code (Insert disease from ICD10)
- L10
- MeSH unique ID (MeSH (Medical Subject Headings))
- D010392