Central Nervous System Neoplasms

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Information
Disease name
Central Nervous System Neoplasms
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04525014 Active, not recruiting Phase 1 RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors January 26, 2023 December 31, 2024
NCT01180881 Active, not recruiting Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment October 2009 June 2024
NCT00329589 Completed Phase 1 A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients September 2005 June 2010
NCT00822432 Completed Coproporphyrine Isomers and Methotrexate Elimination October 2007 August 2011
NCT00185848 Completed Phase 1 Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis April 2005 June 2013
NCT00328458 Completed Phase 1 EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients February 2004 July 2009
NCT01931098 Completed Phase 2 Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab December 10, 2015 September 12, 2019
NCT02291822 Completed Retrospective Study of MRI in Pediatric Patients November 2014 December 2015
NCT03147989 Completed Retrospective Study of MRI With MULTIHANCE at 0.10 and 0.05 mmol/Kg Dose in CNS Patients May 18, 2017 March 16, 2018
NCT03188354 Completed N/A Diagnostic Assessment of 18F-fluciclovine and 18F-FDG -PET/MRI of Primary Central Nervous System Lymphoma November 1, 2017 December 31, 2023
NCT03257631 Completed Phase 2 A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors September 18, 2017 September 14, 2023
NCT03434262 Completed Phase 1 SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors March 5, 2018 May 24, 2024
NCT03750188 Completed Evaluation of Safety and Efficacy of ProHance in Pediatric Patients <2yrs November 1, 2018 October 16, 2019
NCT05850377 Not yet recruiting 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas June 1, 2023 May 31, 2026
NCT04541082 Recruiting Phase 1 Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms October 26, 2020 February 2025
NCT04859543 Recruiting N/A Pediatric Prospective Personalized Immune and Target Identification Trial February 1, 2021 December 31, 2024
NCT05835687 Recruiting Phase 1 Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors April 27, 2023 March 2028
NCT05386108 Recruiting Phase 1/Phase 2 Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/HER2- Breast Cancer August 31, 2022 December 2025
NCT01582152 Terminated Phase 1/Phase 2 Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma July 2012 March 2016
NCT04096716 Terminated Phase 1 Mapping Draining Lymph Nodes in CNS Malignancies December 3, 2019 April 30, 2022
NCT00629187 Terminated Phase 1 Safety Study of High Dose Temozolomide to Treat Relapsed/Refractory Central Nervous System (CNS) Malignancy April 2004 April 2012
NCT02095353 Terminated Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients September 1, 2014 March 7, 2017
NCT02692898 Terminated Biomarker Analysis of Central Nervous System Tumors February 25, 2016 November 15, 2019
NCT04671368 Unknown status N/A Diagnostic Efficiency of Artificial Intelligence for Surgical Neuropathology February 2021 February 2022
NCT01579253 Unknown status Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients April 2012
MeSH unique ID (MeSH (Medical Subject Headings))
D016543