Systemic Inflammatory Response Syndrome
Information
- Disease name
- Systemic Inflammatory Response Syndrome
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05229822 | Active, not recruiting | Bacterial Translocation Markers as Predictors of Infectious and Inflammatory Complications in Acute Bowel Obstruction | March 1, 2021 | December 31, 2023 | |
| NCT03807414 | Active, not recruiting | Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients | June 28, 2019 | December 31, 2024 | |
| NCT04681066 | Active, not recruiting | Phase 2 | A Study of Auxora in Patients With Acute Pancreatitis and Accompanying SIRS | March 24, 2021 | September 2024 |
| NCT00356746 | Completed | Inflammatory Response During Anesthesia and Surgery | March 2006 | March 2009 | |
| NCT00417235 | Completed | Phase 4 | Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU Patients | January 2007 | June 2008 |
| NCT00438269 | Completed | Phase 2 | Pilot Study of the Utility of Empiric Antibiotic Therapy for Suspected ICU-Acquired Infection | February 2003 | March 2005 |
| NCT00448968 | Completed | The Utility of Ischemia Modified Albumin (IMA) in Sepsis | March 2007 | September 2007 | |
| NCT00459511 | Completed | The Importance of Adrenomedullin (AM) on ACTH-Cortisol-Glucose Axis | January 2006 | October 2006 | |
| NCT00490828 | Completed | Phase 4 | Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery | June 2007 | August 2008 |
| NCT00519350 | Completed | Towards a High-fat Feeding Intervention Study: Identification of Markers for Inflammation and Organ Damage | August 2007 | June 2009 | |
| NCT00706771 | Completed | Phase 2 | Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study | February 2010 | September 2012 |
| NCT00708747 | Completed | Phase 4 | Biseko Versus Albumin in Systemic Inflammatory Response Syndrome (SIRS) Patients | July 1996 | September 2003 |
| NCT05469048 | Completed | Near Patient Molecular Testing in Sepsis | March 12, 2020 | October 31, 2022 | |
| NCT00219375 | Completed | Phase 4 | Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan | June 2004 | |
| NCT00293592 | Completed | N/A | Dexamethasone for Cardiac Surgery Trial | May 2006 | December 2012 |
| NCT01296074 | Completed | N/A | Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response | March 2011 | August 2011 |
| NCT01322074 | Completed | Systemic Inflammation Versus Acute Pain in Total Knee Arthroplasty (TKA) | August 2009 | October 2011 | |
| NCT01388725 | Completed | Comparison the Value of Several Biomarkers of Sepsis | September 2009 | July 2011 | |
| NCT01592526 | Completed | Early Phase 1 | Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers | June 2012 | December 2015 |
| NCT01636232 | Completed | Vitamin D and Critically Ill Patients | October 2011 | December 2011 | |
| NCT01708759 | Completed | IL8 Monitoring and Its Correlation With 251-gene Polymorphism | November 2012 | February 2013 | |
| NCT01752348 | Completed | N/A | Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals. | February 2013 | November 2014 |
| NCT01998139 | Completed | Endothelial Microparticles as a Biomarker for Diagnosis and Prognosis in Early Sepsis | July 2013 | February 2019 | |
| NCT02077491 | Completed | N/A | The Effect of Protein and Resistance Training on Muscle Mass in Acutely Ill Old Medical Patients | April 2013 | May 2014 |
| NCT02193477 | Completed | N/A | Effect of TEAS on the Incidence Rate of SIRS in Patients Undergoing Abdominal Surgery | July 2014 | January 2015 |
| NCT02308371 | Completed | N/A | PPV to Guide Fluid Management in the PICU | November 2014 | June 2016 |
| NCT02320539 | Completed | MicroRNA Diagnostics in Subarachnoid Hemorrhage 2 | November 2014 | May 2015 | |
| NCT02321072 | Completed | Phase 4 | Optimal Oxygenation in the Intensive Care Unit | February 2015 | May 2019 |
| NCT02324140 | Completed | Inflammatory Response in Aortic Valve Replacement | June 2012 | May 2015 | |
| NCT02399397 | Completed | Phase 4 | Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics | February 2014 | December 2015 |
| NCT02455180 | Completed | Phase 4 | Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients | March 2015 | November 2016 |
| NCT02518087 | Completed | N/A | Increased Adsorption Membranes During Cardiopulmonary Bypass | September 2016 | January 15, 2022 |
| NCT02563652 | Completed | Can Biomarkers Aid in the Prediction of Postoperative Pain and Circulatory Instability After Major Abdominal Surgery? | September 2015 | September 2018 | |
| NCT02568410 | Completed | Platelets as Regulators of Inflammation in Cardiac Surgery | October 2015 | May 2019 | |
| NCT02668406 | Completed | Study to Obtain Blood and Voided Urine Samples to Improve the Diagnosis of Melioidosis | February 2016 | September 30, 2018 | |
| NCT02728921 | Completed | Phase 4 | The Importance of Albumin Infusion Rate for Plasma Volume Expansion Following Major Abdominal Surgery | April 2014 | November 2016 |
| NCT02852902 | Completed | Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study. | January 1, 2016 | January 1, 2018 | |
| NCT02866825 | Completed | Phase 2 | Studying Complement Inhibition in Complex Cardiac Surgery | May 2016 | January 2017 |
| NCT02898948 | Completed | Procalcitonin (PCT) as a Diagnostic Marker of Bacterial Infection in the Patients Admitted for Fever and/or Inflammatory Syndrome to the Internal Medicine Department | February 11, 2016 | October 18, 2016 | |
| NCT02902939 | Completed | N/A | Myeloid-Derived Supressor Cells in Cardiac Surgery Patients | September 2016 | July 19, 2018 |
| NCT02927054 | Completed | N/A | Effect of Education on Resident Physician Knowledge of Sepsis | July 2014 | September 2016 |
| NCT03085615 | Completed | N/A | Feeding the Critically Ill During Phases of Altered Redox Status | March 15, 2017 | October 13, 2018 |
| NCT03125941 | Completed | Phase 4 | High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy | March 27, 2017 | April 22, 2018 |
| NCT03314831 | Completed | The Role of Myristic Acid in Serum for Early Diagnosis of Sepsis and Comparison With Selected Biomarkers of Sepsis | October 24, 2017 | December 31, 2022 | |
| NCT03401190 | Completed | Phase 2 | CM4620 Injectable Emulsion Versus Supportive Care in Patients With Acute Pancreatitis and SIRS | March 12, 2018 | April 30, 2019 |
| NCT03427307 | Completed | Serum Level of Lipopolysaccharide-binding Protein (LBP) and Atherosclerosis in Hemodialysis Patients | June 3, 2018 | January 31, 2021 | |
| NCT03589495 | Completed | Phase 4 | Safety and Efficacy of Adding Intravenous N-acetyl Cysteine in Colon Surgeries | July 30, 2015 | October 15, 2016 |
| NCT03604731 | Completed | Persistent Multiorgan Failure in Intensive Care Units | January 1, 2017 | September 1, 2020 | |
| NCT03863015 | Completed | Phase 2 | IL-6 Inhibition for Modulating Inflammation After Cardiac Arrest | March 4, 2019 | June 30, 2020 |
| NCT03876041 | Completed | Phase 4 | Evaluation of Corticosteroid in Systemic Inflammatory Response Syndrome | September 1, 2019 | November 1, 2020 |
| NCT04624776 | Completed | Phase 2 | Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest | October 10, 2020 | February 28, 2023 |
| NCT05213923 | Completed | N/A | ED Tracking Sheet Implementation | July 1, 2021 | June 1, 2022 |
| NCT00021502 | Completed | Phase 3 | Safety and Efficacy of PHP in the Treatment of Shock Associated With Systemic Inflammatory Response Syndrome (SIRS) | March 2001 | May 2004 |
| NCT05725798 | Completed | Perioperative Sitagliptin Medication for Reduction of the Inflammatory Response Associated With Cardiopulmonary Bypass | February 1, 2022 | August 1, 2023 | |
| NCT05979207 | Completed | Phase 1 | Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum | August 1, 2023 | October 30, 2023 |
| NCT01020409 | Completed | INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery | October 2009 | November 2012 | |
| NCT01042132 | Completed | N/A | Intramedullary Femoral Reaming, Human Study | May 2003 | May 2012 |
| NCT01167075 | Completed | N/A | A Study in Critically Ill Patients Investigating Tolerability and Efficacy of Low-volume Pharmaconutrition (Intestamin) | February 2006 | February 2009 |
| NCT05470907 | Enrolling by invitation | Registry for Hemoperfusion of Covid-19 ICU Patients | July 21, 2022 | September 30, 2024 | |
| NCT06195267 | Not yet recruiting | N/A | Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Sivelestat) VI | February 1, 2024 | December 31, 2025 |
| NCT05608096 | Recruiting | European Registry for Hemadsorption in Sepsis With the Seraph Filter | October 25, 2022 | December 30, 2025 | |
| NCT04033224 | Recruiting | Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure | July 16, 2019 | December 2024 | |
| NCT01904188 | Recruiting | Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate? | June 2015 | July 2027 | |
| NCT05172739 | Recruiting | Phase 4 | Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC | October 1, 2021 | November 1, 2026 |
| NCT05969275 | Recruiting | Phase 2 | Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock | February 14, 2024 | March 31, 2027 |
| NCT06052436 | Recruiting | Phase 1/Phase 2 | Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) | June 27, 2023 | December 31, 2027 |
| NCT06122987 | Recruiting | Phase 4 | Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock | December 4, 2023 | January 2025 |
| NCT05663216 | Recruiting | Determinants of Vascular Leakage During Systemic Inflammatory Response Syndrome | May 31, 2023 | July 1, 2028 | |
| NCT06028789 | Recruiting | AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis | April 1, 2022 | June 30, 2024 | |
| NCT04580680 | Recruiting | Extracorporeal Blood Purification Therapy in Critically Ill Patients (GlobalARRT) | November 1, 2020 | September 30, 2024 | |
| NCT05637281 | Recruiting | N/A | Clinical Efficacy of Indomethacin in Early Treatment of Acute Pancreatitis | December 11, 2022 | December 11, 2023 |
| NCT06057207 | Recruiting | Perioperative Adiponectin and Postoperative Inflammatory Response After Major Abdominal Surgery | July 27, 2023 | December 1, 2024 | |
| NCT00708799 | Terminated | Phase 2 | Efficacy of Macrolide Immunomodulation in Severe Sepsis. | November 2007 | November 2013 |
| NCT00773110 | Terminated | Phase 2 | Study of Albumin to Reduce Inflammation Following Surgery | December 2008 | May 2011 |
| NCT00875888 | Terminated | N/A | High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic Shock | February 2004 | June 2009 |
| NCT03066388 | Terminated | N/A | Accuracy of Pulse Pressure Variations Measured by a Non Invasive Digital Device to Predict Fluid Responsiveness | April 2012 | June 2013 |
| NCT00159926 | Terminated | Phase 3 | Cleansing of Suction Blood in Cardiac Surgery for Reduced Inflammatory Response | January 2003 | February 2004 |
| NCT01731106 | Terminated | Cerebral Autoregulation in Non Neurological Critical Patients. | June 2012 | March 2018 | |
| NCT03407287 | Terminated | Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status | January 8, 2018 | December 1, 2020 | |
| NCT01838525 | Unknown status | Alpha-1-acid Glycoprotein as a Biomarker of Developmental Diagnosing and Monitoring Effectiveness in Sepsis | April 2011 | June 2013 | |
| NCT02055105 | Unknown status | N/A | Modulation of Molecular Fingerprinting in Pediatric Sepsis | March 2014 | August 2015 |
| NCT03369275 | Unknown status | Phase 2 | Cellular Immunotherapy for Septic Shock | March 2018 | October 2020 |
| NCT03145220 | Unknown status | Phase 2 | Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG) | June 2016 | October 2018 |
| NCT02279147 | Unknown status | Phase 1/Phase 2 | Cholinergic Anti-inflammatory Pathway in Prevention & Treatment of the SIRS in Patients With Jaundice After Operation. | August 2014 | September 2017 |
| NCT00254176 | Unknown status | Phase 2/Phase 3 | Cysteine Supplementation in Critically Ill Neonates | September 2006 | July 2011 |
| NCT02820090 | Unknown status | The Predictive Effect of the Inflammatory Response on the Evacuation of Mechanical Ventilation and the Mechanism | May 2014 | April 2017 | |
| NCT03283345 | Unknown status | N/A | Effect of Menstrual Cycle on Traumatic Systemic Response | June 2008 | November 2018 |
| NCT03001687 | Unknown status | N/A | Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients | January 2017 | December 2017 |
| NCT02957175 | Unknown status | Immunophenotyping of Patients With Postoperative SIRS | November 2016 | May 2021 | |
| NCT03617796 | Unknown status | Prognostic Value of CD64 Marker for Patients in Intensive Care Unit | September 10, 2018 | December 31, 2018 | |
| NCT00427388 | Unknown status | Phase 4 | Steroids In caRdiac Surgery Trial (SIRS Trial) | June 2007 | August 2014 |
| NCT01157299 | Unknown status | Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO | September 2009 | September 2010 | |
| NCT04687384 | Unknown status | N/A | Systemic and Peritoneal Inflammatory Response In Robotic-assisted And Laparoscopic Surgery for Colon Cancer | August 1, 2021 | September 1, 2022 |
| NCT03939273 | Unknown status | N/A | The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery | March 2022 | March 2023 |
| NCT00994877 | Unknown status | Thromboelastography in in Patients With Sepsis | March 2009 | May 2010 | |
| NCT00893932 | Unknown status | Leptin: a Therapeutic Option for Treating Catabolic States and Malnutrition in Critically Ill Patients | August 2008 | December 2009 | |
| NCT01579396 | Withdrawn | N/A | High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery | April 2012 | December 2013 |
| NCT00739557 | Withdrawn | A Pilot Study to Evaluate the Systemic Inflammatory Response of Thoracoabdominal Aortic Aneurysm Repair. | August 2008 | August 2009 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D018746