Chronic liver disease

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Information
Disease name
Chronic liver disease
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00402402 Completed Phase 4 Comparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in Patients With Chronic Liver Disease October 2006 July 2007
NCT00629486 Completed N/A Genetic Polymorphisms of Interleukin-1B and TNF-A and HBV-Related Hepatocellular Carcinoma January 2007 May 2008
NCT00629603 Completed N/A Polymorphisms of Fibrosis-Relating Genes on Outcome of HCV-Related Chronic Liver Disease January 2007 September 2009
NCT00736840 Completed Phase 3 BreathID 13C-Methacetin Breath Test for Detecting Cirrhosis August 2008 September 2009
NCT00756171 Completed Phase 2/Phase 3 Colesevelam Versus Placebo in Cholestatic Pruritus September 2008 December 2009
NCT00945568 Completed N/A Preoperative Oral Supplementation With Branched-Chain Amino Acids (BCAA) Improves Postoperative Quality of Life May 2007 June 2009
NCT01008293 Completed Phase 2/Phase 3 Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life October 2009 October 2012
NCT01195181 Completed Phase 4 Different PEG-interferon and Ribavirin Schedules for Chronic Hepatitis C in the Real Clinical Practice. September 2005 August 2010
NCT01283230 Completed Evaluation of Liver Fibrosis Staging With Acoustic Radiation Force Impulse Elastography July 2010 April 2011
NCT01384565 Completed Phase 3 G-CSF and Erythropoetin in Survival of Patients With Decompensated Liver Disease July 2011 March 2013
NCT01393665 Completed Phase 2 Study to Evaluate Efficacy, Safety and Tolerability of PENNEL Capsule in the Patients With Chronic Liver Disease December 1996 October 1997
NCT01393678 Completed Phase 3 Study to Evaluate Efficacy and Safety of PENNEL Capsule in the Patients With Chronic Liver Disease November 1997 May 1998
NCT01600105 Completed Phase 4 Detection of Liver Fibrosis With Magnetic Resonance Imaging (MRI) October 2010 July 31, 2017
NCT01634698 Completed N/A Relative-dose-response Test (RDR) Adaptation for Chronic Liver Disease October 2007 December 2008
NCT01644656 Completed N/A Non-invasive Diagnosis of Portal Hypertension With Acoustic Radiation Force Impulse (ARFI) July 2012 September 2018
NCT01747772 Completed N/A Sonoelastography: Ultrasound Method to Measure Liver Fibrosis February 2010 February 14, 2014
NCT01825213 Completed Stratification of Patients With Chronic Liver Disease Using Multi Spectral CT November 2013 October 2016
NCT01851252 Completed Phase 1 MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy October 2013 August 2017
NCT01944878 Completed The Association With Peptic Ulcer Disease and Hepatic Vein Pressure Gradient May 2013 August 2013
NCT02084160 Completed Prediction Value of the BreathID 13C-Methacetin Breath Test for Hepatic Decompensation March 2014 November 2018
NCT02294292 Completed N/A Therapeutic Approach to Diastolic Dysfunction in Chronic Liver Disease Patients and Its Impact on Morbidity and Mortality July 1, 2014 August 31, 2016
NCT02347319 Completed Phase 4 To Evaluate the Efficacy of DDB/Garlic Oil in Patients With Elevated Transaminase Chronic Liver Disease April 2012 June 2013
NCT02359266 Completed N/A Vitamin D Improves Depression in Liver Patients December 2011 December 2013
NCT02389621 Completed Phase 3 Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Elective Invasive Procedures June 15, 2015 April 19, 2017
NCT02652221 Completed N/A Determination of Liver Stiffness in Chronic Liver Disease Patients by Acoustic Radiation Force Imaging (ARFI) Ultrasound June 2014 May 2016
NCT02715973 Completed N/A Nutritional Assessment Tool and Nutritional Intervention in Childhood Chronic Liver Disease January 1, 2016 October 31, 2017
NCT02802761 Completed Nutritional Assessment Tool in Childhood Chronic Liver Disease January 1, 2016 October 31, 2017
NCT02859753 Completed N/A Comparison of Response and Recurrence Rates Following Percutaneous Microwave Coagulation Therapy Versus Percutaneous Radiofrequency Ablation January 15, 2014 March 18, 2020
NCT02973516 Completed Phase 2 Proof of Concept Study Concerning Efficacy of P03277 MR Imaging in HCC Diagnosis December 2016 April 4, 2019
NCT03087344 Completed N/A Postprandial Liver and Spleen Stiffness Measurements in the Noninvasive Diagnosis of Cirrhosis October 31, 2017 June 30, 2018
NCT03246048 Completed Long Term Follow-up of Hepatitis C Cured Patients January 2016 June 2021
NCT03440164 Completed Superior Silybin Bioavailability in Healthy Volunteers November 11, 2016 December 15, 2016
NCT03583996 Completed N/A The SHUNT-V Study for Varices January 23, 2019 May 7, 2021
NCT03704792 Completed N/A Validation of the Second Generation of the Controlled Attenuation Parameter (CAP) Using the MRI-PDFF as Reference September 24, 2019 November 30, 2021
NCT03847753 Completed Exploring the Comorbidity Between Mental Disorders and General Medical Conditions January 1, 2000 January 31, 2020
NCT04022941 Completed N/A Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease. April 1, 2017 December 31, 2018
NCT04099407 Completed Phase 2 Pirfenidone and Advanced Liver Fibrosis. August 1, 2019 December 31, 2020
NCT04146805 Completed Phase 1 Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BLD-0409 in Healthy Subjects January 10, 2020 April 12, 2021
NCT04246918 Completed N/A Effect of BCAA Supplementation on Muscle Mass, Muscle Quality and Molecular Markers of Muscle Regeneration in CLD Patients June 1, 2020 September 30, 2022
NCT04380493 Completed The Use of the Transient Elastography Paediatric Probe, Compared to the M Probe, Indirect Biomarkers and Histology May 2015 December 2019
NCT04384159 Completed Combination Diagnostic Strategies in NAFLD November 30, 2011 July 31, 2019
NCT04439084 Completed COVID-19 in Patients With Chronic Liver Diseases March 6, 2020 July 31, 2021
NCT04455464 Completed N/A Effect of Midodrine on HVPG in Advanced Chronic Liver Disease July 11, 2020 December 13, 2021
NCT04751045 Completed N/A Comparison and Outcomes of Endoscopic Ultrasound Liver Biopsies Versus Percutaneous Liver Biopsies October 25, 2020 October 1, 2021
NCT04775069 Completed Phase 4 Antibody Response to COVID-19 Vaccines in Liver Disease Patients May 21, 2021 September 30, 2023
NCT04806607 Completed N/A 19Gauge Fine Needle Biopsy (FNB) Versus 22Gauge FNB for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB) April 30, 2021 March 16, 2022
NCT05036603 Completed N/A Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns April 1, 2022 August 15, 2022
NCT05044663 Completed Liver and Splenic Stiffness in Predicting Esophageal Varices Needing Treatment in NASH Related Compensated Advanced Chronic Liver Disease. September 18, 2021 February 28, 2023
NCT05097963 Completed N/A A Study to Evaluate Liver Stiffness With Shear Wave Elastography January 19, 2022 January 12, 2023
NCT05224037 Completed N/A Comparative Efficacy of Liver Fibrosis and Steatosis Assessment With Fibroscan and iLivTouch January 21, 2022 December 31, 2022
NCT05241158 Completed N/A Impact of Counselling and Visual Aid on Anxiety in Endoscopic Patients August 16, 2018 February 4, 2020
NCT06267794 Completed Phase 2 Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis. June 26, 2015 March 24, 2023
NCT06272630 Enrolling by invitation Phase 4 Study to Evaluate the Efficacy and Safety of DWJ1464 in Patients With Chronic Liver Disease February 6, 2023 August 31, 2024
NCT05836246 Enrolling by invitation The Development of Quantitative Ultrasound Imaging Software Platform September 1, 2020 March 31, 2026
NCT05809141 Not yet recruiting Comparison Between Thromboelastography and Conventional Coagulation Tests in Pediatrics With Chronic Liver Disease April 1, 2023 March 31, 2024
NCT05965843 Not yet recruiting Intervention, Prognosis and Mechanism of Covid-19 Infection in Patients With Underlying Diseases August 2023 December 2024
NCT06387745 Not yet recruiting N/A Referral of Patients to Hepatology With Hepatoscope May 2024 December 2025
NCT05095714 Not yet recruiting N/A FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer. December 1, 2021 December 1, 2027
NCT05788627 Not yet recruiting Phase 4 Effectiveness of Oral Lactulose Versus Lactulose Enema in Hepatic Encephalopathy April 2023 November 2023
NCT06318949 Not yet recruiting N/A Albumin Modifications as Early Biomarkers of Chronic Liver Diseases June 1, 2024 December 1, 2029
NCT05744713 Not yet recruiting An Observational Study of Patients With Chronic Liver Disease May 1, 2023 December 31, 2037
NCT05312853 Not yet recruiting Evaluating the Diagnostic and Predictive Value of Non-invasive Tests (NITs) on the Progression of Chronic Liver Disease. January 15, 2024 December 31, 2034
NCT06432582 Recruiting hepatomiR cACLD Study May 15, 2024 June 2026
NCT05661331 Recruiting VIATORR Device Registry February 21, 2023 January 10, 2028
NCT05849558 Recruiting Phase 4 Study to Compare the Efficacy & Safety of Ursoplus Capsules vs. UDCA vs. Placebo Among Chronic Liver Disease Patients February 22, 2022 December 31, 2023
NCT02037867 Recruiting Nottingham Community Liver Biomarkers Cohort May 2013 May 2033
NCT02060565 Recruiting Prognosis Value of Non-invasive Methods for the Diagnosis of Chronic Liver Disease February 2014 February 2034
NCT05532124 Recruiting Phase 2 Part A: In Patients With Chronic Liver Diseases, LAENNEC (Human Placenta Hydrolysate) is to Assess Safety and Tolerability After the Doses of Doses. Part B: Part A, it is to Determine the Optimal Dose by Evaluating Two Capacity and Placebo Groups. June 1, 2021 June 2023
NCT04802954 Recruiting N/A Risk Stratification of Hepatocarcinogenesis Using a Deep Learning Based Clinical, Biological and Ultrasound Model in High-risk Patients September 1, 2021 September 2025
NCT06160635 Recruiting D-SOLVE Cohorts (Cohort A and B) February 22, 2023 September 30, 2026
NCT04915287 Recruiting Phase 4 Efficacy of Avatrombopag in Thrombocytopenic Patients With Chronic Liver Disease Undergoing an Elective Procedure June 6, 2021 July 31, 2023
NCT04943978 Recruiting Prospective Studies on Immunopathogenesis of Liver Fibrosis February 1, 2014 January 31, 2026
NCT05653830 Recruiting Observational Clinical Study of the Natural Course and Long-term Prognosis of Patients With Chronic Liver Disease October 1, 2022 December 31, 2025
NCT06227988 Recruiting ASSESSMENT OF SURGICAL RISK IN PATIENTS WITH CHRONIC LIVER DISEASE USING VOCAL PENN SCORE June 20, 2023 July 30, 2025
NCT03840928 Recruiting PatientSpot Formerly Known as ArthritisPower April 1, 2015 March 1, 2025
NCT05335603 Recruiting An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis August 24, 2020 August 2036
NCT04588077 Recruiting Phase 4 Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis September 14, 2020 July 1, 2024
NCT05204251 Recruiting Evaluation of the Quality of Life in Patients Referred for Transjugular Intrahepatic Portosystemic Shunt April 11, 2022 April 2024
NCT02650011 Suspended Clinical Features and Natural History of Acute-on-Chronic Liver Failure in Korean Patients With Chronic Liver Disease October 2015 December 2018
NCT02530567 Terminated N/A Non-invasive Evaluation of Portal Pressure by MRI October 2015 July 2019
NCT01433016 Terminated Phase 2 Detection of Hepatocellular Carcinoma (HCC) With Octanoate Breath ID Test Compared to MRI November 2011 May 2013
NCT02499185 Terminated Phase 4 Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative Patients April 1, 2015 August 31, 2017
NCT01756690 Terminated Predicting Lung Injury From Transfusion in Patients With Liver Disease October 2011 December 2016
NCT00599352 Terminated N/A Hypovitaminosis D and an Inadequate PTH Response in Chronic Liver Disease Patients January 2008 January 2013
NCT02086708 Terminated N/A Ultrasound Method to Measure Fibrosis of the Liver in Children June 2010 March 2015
NCT00678587 Terminated Phase 3 Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocytopenia Undergoing Elective Invasive Procedures June 2008 October 2009
NCT02949375 Terminated Phase 2 Trial to Examine the Effect of Two Doses of GRI-0621 in Patients With Chronic Liver Disease September 2015 June 2019
NCT04015570 Unknown status N/A Efficacy and Safety of Plasma Exchange Compared to Standard Medical Therapy in Patients With Severe Drug Induced Liver Injury With or Without Underlying Chronic Liver Disease. July 9, 2019 July 1, 2020
NCT03212872 Unknown status N/A Blood Ammonia as Predictor for Esophageal Varices and Risk of Bleeding July 7, 2016 December 31, 2018
NCT03492879 Unknown status N/A Non Invasive Electrical Impedance Technology (EIT) for Diagnosing Liver Diseases Severity May 15, 2018 May 30, 2019
NCT05296434 Unknown status Delta Radiomics for Liver Function Evaluation April 1, 2022 December 31, 2022
NCT00629668 Unknown status N/A Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease January 2007 December 2007
NCT00630006 Unknown status N/A Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease January 2007 December 2008
NCT05397860 Unknown status N/A Radiofrequency Ablation With Gradual Radiofrequency Energy Increment for Hepatocellular Carcinoma Treatment January 6, 2020 August 30, 2023
NCT01205074 Unknown status Phase 2/Phase 3 ¹³C-Methacetin Breath Test (MBT) Methodology Study September 2010
NCT01246388 Unknown status Non-Invasive Evaluation of Fibrosis and Steatosis in Chronic Hepatopathy May 2010 December 2014
NCT01335568 Unknown status Phase 1 Hepatocyte Matrix Implant Study Indonesia April 2011 December 2012
NCT01337440 Unknown status Phase 4 Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver Diseases April 2010 March 2013
NCT04526548 Unknown status A Diagnostic Study on Patients With Drug-induced Liver Injury October 2020 October 2021
NCT04622449 Unknown status Etiopathogenesis of Anemia in Chronic Liver Disease September 1, 2020 December 31, 2021
NCT04734496 Unknown status Evaluation of the Mechanisms of Sarcopenia in Chronic Inflammatory Disease: Protocol for a Prospective Cohort Study January 1, 2019 September 1, 2021
NCT04774601 Unknown status Elastography in Chronic Liver Disease in Children June 2022 September 2023
NCT01948687 Unknown status Real Time Elastography in Liver Fibrosis August 2013 November 2014
NCT02184000 Unknown status The Role of Strain Elastography in Staging Liver Fibrosis March 2014 September 2014
NCT02618798 Unknown status Hepatic Venous Pressure Gradient and Platelet Activation in Chronic Liver Disease January 2014 January 2016
NCT05118308 Unknown status N/A EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement November 4, 2021 December 4, 2023
NCT01314508 Withdrawn N/A Increlex Treatment of Children With Chronic Liver Disease and Short Stature June 2011
NCT02899325 Withdrawn FDGal PET/CT to Detect Hepatocellular Carcinoma October 2019 October 2021
NCT00424684 Withdrawn N/A Comparison of the Quantiferon®-TB GOLD (in Tube) Assay With Tuberculin Skin Testing for Detecting Latent Tuberculosis Infection in Patients With Chronic Liver Disease Being Evaluated for or Awaiting Liver Transplantation January 2007
NCT04775056 Withdrawn A Study to Evaluate Vaccines Against COVID-19 in the Real World August 2022 December 31, 2023
MedGen concept unique identifier (MedGen Concept name)
C0341439
MedGen unique identifier (MedGen Concept name)
574392