hepatitis A
Information
- Disease name
- hepatitis A
- Disease ID
- DOID:12549
- Description
- "A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus, which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice." [url:http\://www.cdc.gov/hepatitis/HAV/index.htm, url:http\://www.cdc.gov/hepatitis/Resources/Professionals/PDFs/ABCTable.pdf]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06058416 | Active, not recruiting | Phase 4 | Immunogenicity and Safety of Hepatitis A Among People Aged 18-50 Years Old | October 24, 2023 | December 31, 2029 |
| NCT00139113 | Completed | Phase 4 | Immunogenicity Study of an Inactivated Hepatitis A Vaccine in Infants and Young Children | September 1996 | June 2001 |
| NCT00139139 | Completed | N/A | A Study to Compare the Efficacy of Hepatitis A Vaccine and Immune Globulin When Given After Exposure to Hepatitis A | September 2003 | May 2005 |
| NCT00197002 | Completed | Phase 3 | Immune Response & Safety of a Hepatitis A Vaccine Given Together With a Pneumococcal Vaccine in Healthy Children 15 m of Age | September 11, 2003 | January 16, 2006 |
| NCT00197015 | Completed | Phase 3 | Immunogenicity & Safety of Hepatitis A Vaccine Co-admin With a Measles/Mumps/Rubella & a Varicella Vaccine in Children | October 6, 2003 | June 9, 2009 |
| NCT00197119 | Completed | Phase 3 | Long-Term Follow-Up Studies at Year 6, 7, 8, 9, 10: 2 Formulations of Combined Hepatitis A/B Vaccine Compared in Subjects Aged 12-15 Years | May 2004 | June 2004 |
| NCT00197171 | Completed | Phase 3 | Long Term F/U Studies at Y5&6 to Demonstrate the Equivalence of 2 Vaccination Schedules of Combined Hepatitis A & B Vaccine | September 2003 | December 2003 |
| NCT00197184 | Completed | Phase 3 | Long Term Follow-up Study at Years 2, 3, 4 and 5 Where 2 Dosing Schedules of the Combined Hepatitis A and B Vaccine Were Compared | November 1, 2003 | March 10, 2004 |
| NCT00197236 | Completed | Phase 3 | Immunogenicity and Safety of Havrix™ Co-Administered With a Diphtheria, Tetanus and Pertussis and a Haemophilus b Vaccine in Children Aged 15 Months | November 11, 2003 | December 3, 2007 |
| NCT00197249 | Completed | Phase 3 | Comparative Study in Healthy Adults Aged 18-50 Yrs Administered With Hepatyrix or Havrix+Typherix or Tiphim Vi, to Compare Reactogenicity & Immunogenicity | May 2002 | November 2005 |
| NCT00237991 | Completed | Safety of GlaxoSmithKline (GSK) Biologicals Hepatitis A Vaccine in Korean Population | June 2005 | ||
| NCT00244374 | Completed | N/A | A Randomized Trial of Vaccine Adherence in Young Injection Drug Users | August 2004 | June 2008 |
| NCT00289718 | Completed | Phase 3 | Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,1,6 Month Schedule | November 1, 2004 | March 2, 2005 |
| NCT00289731 | Completed | Phase 4 | Effect of Risk Factors Likely to Influence Immuno of Combined Hepatitis A & B Vacc vs Monovalent Hepatitis A & B Vacc | November 24, 2003 | December 21, 2004 |
| NCT00289744 | Completed | Phase 3 | Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,6 Month Schedule | February 16, 2004 | April 15, 2009 |
| NCT00289757 | Completed | Phase 4 | Long-Term Immune Persistence of GlaxoSmithKline Biologicals' Inactivated Hepatitis A Vaccine, Injected According to 0, 6-month Schedule | January 1, 2004 | March 1, 2013 |
| NCT00291876 | Completed | Phase 4 | Long-Term Immune Persistence of GlaxoSmithKline Biologicals' Inactivated Hepatitis A Vaccine Injected According to a 0, 12-month Schedule | January 1, 2004 | March 1, 2013 |
| NCT00313950 | Completed | Phase 4 | Immunogenicity and Safety of Hepatitis A Vaccine Given at the Same Time of Measles, Mumps, Rubella Combined Vaccine | September 2006 | April 2010 |
| NCT00326183 | Completed | Phase 4 | Hepatitis A Vaccine, Inactivated and Measles, Mumps, Rubella and Varicella Virus Vaccine Live Safety Study (V251-066)(COMPLETED) | March 26, 2007 | January 15, 2008 |
| NCT00338351 | Completed | Phase 2 | Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' 10-valent Pneumococcal Conjugate Vaccine. | April 2006 | October 2006 |
| NCT00289770 | Completed | Phase 3 | Long-term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,1,6 Mth Schedule in Healthy Adults | November 1, 2004 | December 20, 2004 |
| NCT01405677 | Completed | Phase 2 | Safety and Immunogenicity of a Paediatric Dose of Virosomal Hepatitis A Vaccine | June 2004 | April 2012 |
| NCT01453348 | Completed | Phase 3 | Study to Evaluate the Safety and Immunogenicity of Combined Hepatitis A/B Vaccine With MenACWY-CRM Conjugate Vaccine | October 2011 | January 2012 |
| NCT01838070 | Completed | Regulatory Post-Marketing Surveillance Study for Hepatitis A Vaccine (AVAXIM 160U) | April 2013 | May 2016 | |
| NCT01865968 | Completed | Phase 4 | Comparison of Immunogenicity and Safety of Inactivated and Live Attenuated Hepatitis A Vaccines in Young Adults | October 2008 | September 2012 |
| NCT01949857 | Completed | Phase 4 | The Immunogenicity and Safety of Inactivated and Live Attenuated Hepatitis A Vaccines | September 2013 | June 2016 |
| NCT02002065 | Completed | The Fifth-year Follow-up Study for the Phase IV Clinical Trial of Hepatitis A Vaccine in Healthy Children | October 2008 | June 2014 | |
| NCT02011763 | Completed | Phase 4 | Safety of Two Doses of Avaxim® 80U Pediatric (Inactivated Hepatitis A Vaccine) in Toddlers, Children and Adolescents | December 2013 | August 2015 |
| NCT02112890 | Completed | Study to Assess Seroprevalence of Hepatitis A, Hepatitis B and Bordetella Pertussis in Mexico | December 10, 2014 | May 2, 2016 | |
| NCT02300792 | Completed | Phase 2 | The Effects of Honey, as a Dietary Supplement in Children With Hepatitis A | November 2013 | November 2014 |
| NCT02445703 | Completed | Phase 4 | Comparison of Immunization Schedules of Inactivated Hepatitis A Vaccine and Combined Hepatitis A and Hepatitis B Vaccine | May 2014 | June 2016 |
| NCT02601040 | Completed | Phase 4 | Immunogenicity and Safety of Inactivated and Live Attenuated Hepatitis A Vaccines | November 2011 | October 2015 |
| NCT03312699 | Completed | Phase 1 | Effects of Aging on Primary and Secondary Vaccine Responses in a 15-Year Longitudinal Cohort | September 19, 2017 | December 31, 2023 |
| NCT03855176 | Completed | Phase 4 | Effectiveness of Booster With 1 or 2 Doses of HAV Vaccine Among HIV-infected Patients | September 12, 2017 | December 30, 2022 |
| NCT04638335 | Completed | What is the Anti-HAV Seroprevalence of Travelers >60 Years or Having Lived in a Tropical Country for >5 Years | October 6, 2019 | March 31, 2022 | |
| NCT00483470 | Completed | Phase 3 | Immunogenicity and Safety of Sanofi Pasteur's AVAXIM 80U Pediatric Vaccine Followed by Booster Dose | June 2007 | August 2008 |
| NCT00534885 | Completed | Phase 4 | Safety, Immunogenicity, and Immune Persistence Study of an Inactivated Hepatitis A Vaccine | March 2006 | October 2017 |
| NCT00603252 | Completed | Phase 4 | Study to Show That the Combined Hepatitis A and B Vaccine is Non-inferior to Monovalent Vaccines in Adults | January 2008 | June 2008 |
| NCT00621764 | Completed | Phase 2 | Immunogenicity and Safety of ChimeriVax™ Japanese Encephalitis Vaccine in Thai Toddlers and Children | March 2008 | May 2013 |
| NCT00684671 | Completed | Phase 4 | Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination | May 26, 2008 | November 3, 2008 |
| NCT00735644 | Completed | Phase 3 | Study of ChimeriVax™-Japanese Encephalitis Vaccine in Toddlers in Thailand and the Philippines | August 2008 | August 2009 |
| NCT00875485 | Completed | Phase 4 | Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™ | May 1, 2009 | July 1, 2014 |
| NCT01000324 | Completed | Phase 4 | Antibody Persistence & Immune Memory in Healthy Adults Previously Vaccinated With Twinrix Adult | November 6, 2009 | July 25, 2014 |
| NCT01037114 | Completed | Phase 4 | Long-term Persistence Study in Healthy Adults Previously Vaccinated With Twinrix Adult | January 27, 2010 | February 28, 2014 |
| NCT01160081 | Completed | Seroprevalence Study of Hepatitis A, Varicella-Zoster, Cytomegalovirus, Herpes Simplex and Bordetella Pertussis | March 2010 | September 2010 | |
| NCT01252680 | Completed | Phase 4 | Immunogenicity and Interchangeability of Two Inactivated Hepatitis A Vaccines | April 2010 | May 2011 |
| NCT01307436 | Completed | Phase 3 | Long Term Follow-up of a Study to Assess the Safety and Immunogenicity of a Hepatitis A Vaccine Administered With and in the Absence of DTPaHibIPV, OPV and MMR Vaccines | March 14, 2007 | July 8, 2013 |
| NCT01341808 | Completed | Phase 4 | Immunogenicity of Hepatitis A Vaccine in Inflammatory Bowel Disease (IBD) Patients | April 2011 | March 2013 |
| NCT01349829 | Completed | Phase 4 | A Study to Evaluate the Safety and Immunogenicity of the Hepatitis A Virus Vaccine HAVpur in Healthy Young Children | March 2010 | April 2011 |
| NCT01353989 | Completed | Hepatitis A Vaccination in the Elderly | July 2010 | July 2015 | |
| NCT06184230 | Not yet recruiting | Phase 4 | Persistence of Hepatitis A Antibody in Healthy Adults ~32 Years Post Vaccination. | January 2024 | June 2025 |
| NCT06298708 | Not yet recruiting | Phase 3 | Immunogenicity and Safety of Inactivated and Live-attenuated HAV Vaccine Among Thai Healthy Children and Adolescents | April 2024 | June 2025 |
| NCT06460545 | Not yet recruiting | Phase 4 | Phase IV Study of Concomitant Administration of the sIPV and HepA | June 15, 2024 | December 15, 2027 |
| NCT05613127 | Not yet recruiting | Phase 3 | To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in Healthy Children Aged From 24mons-15yrs | December 2022 | November 2024 |
| NCT00119743 | Terminated | Phase 3 | A Efficacy Against Otitis Media in Children With 11 Valent Pneumococcal Vaccine | October 2000 | June 2004 |
| NCT00451984 | Unknown status | Phase 3 | Hepatitis Vaccination in HIV Infection: Role of Adjuvant Interleukin-2 | March 2007 | |
| NCT03231605 | Unknown status | Phase 4 | Comparative Immunogenicity Study of Two Hepatitis A Vaccines | July 26, 2017 | December 29, 2017 |
| NCT00926419 | Unknown status | Phase 2/Phase 3 | Serological Evaluation of Varicella and Hepatitis A Vaccines Using Injector Delivery | June 2009 | May 2010 |
| NCT03330171 | Unknown status | Phase 4 | Safety and Immunogenicity of Measles Vaccine, Varicella Vaccine and Hepatitis-A Vaccine | April 10, 2017 | December 1, 2022 |
| NCT02605538 | Withdrawn | N/A | Hepatitis B in Cystic Fibrosis and Latent Tuberculosis Respectively | September 1, 2015 | December 31, 2025 |
| NCT02124785 | Withdrawn | Phase 4 | Evaluation of the Long-term Persistence of Hepatitis A Antibodies in Healthy Adults Who Were Vaccinated 21-25 Years Earlier With GlaxoSmithKline (GSK) Biologicals' Hepatitis A Vaccine, Havrix® | May 2015 | July 2019 |
| NCT03183492 | Withdrawn | Phase 4 | Immunogenicity and Persistence of GlaxoSmithKline (GSK) Biologicals' Havrix® in Healthy Adult Subjects Vaccinated at Infancy Under the Hepatitis A Universal Mass Vaccination (UMV) Program in Israel | May 7, 2018 | January 28, 2019 |
| NCT03445416 | Withdrawn | N/A | Increasing Healthcare Engagement Via Routine Vaccination Among Young Black Men Who Have Sex With Men | September 2018 | August 2020 |
| NCT02135666 | Withdrawn | Phase 4 | Evaluation of the Long-term Hepatitis A and B Antibody Persistence in Healthy Adult Subjects, Primed 16 to 20 Years Earlier With GSK Biologicals' Combined Hepatitis A and B Vaccine, Twinrix® (SB208127) in Study HAB-084 (208127/084) | May 2015 | October 2019 |
- Disase is a (Disease Ontology)
- DOID:934
- Cross Reference ID (Disease Ontology)
- MESH:D006506
- Cross Reference ID (Disease Ontology)
- NCI:C3096
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:40468003
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0019159
- Exact Synonym (Disease Ontology)
- Viral hepatitis, type A
- Disase Synonym (Disease Ontology)
- Viral hepatitis A
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006506