meningitis
Information
- Disease name
- meningitis
- Disease ID
- DOID:9471
- Description
- "A central nervous system disease that is characterized by an inflammation of the pia-arachnoid meninges. It can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells." [url:http\://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mmed.section.5162]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04190303 | Active, not recruiting | BIGlobal Intervention Study: Improving Diagnosis and Management of Suspected Brain Infections Globally | February 17, 2021 | December 31, 2024 | |
| NCT05093829 | Active, not recruiting | Phase 3 | Meningococcal Serogroup ACYWX Conjugate Vaccine in Comparison With MenACWY-TT Conjugate Vaccine | March 24, 2022 | July 2025 |
| NCT00219401 | Completed | Phase 2 | Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea | May 2005 | May 2010 |
| NCT00254995 | Completed | Descriptive, Post-marketing, Surveillance Safety Study of Menactra Vaccine | July 2005 | May 2013 | |
| NCT00258856 | Completed | Phase 2 | Persistence of Antibodies in Children Aged 7 to 15 Years Who Previously Received One Dose of Menactra® or Menomune® | January 2006 | November 2007 |
| NCT00269477 | Completed | Phase 2 | Persistence of Antibodies in Adolescents and Adults 15 to 23 Years Who Received One Dose of Menactra® or Menomune® | December 2005 | December 2007 |
| NCT00325130 | Completed | Phase 3 | Concomitant Use of Gardasil (V501) (Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diphtheria, Tetanus, Pertussis Vaccine and Meningococcal Conjugate Vaccine in Adolescents (V501-025) | April 2006 | April 2007 |
| NCT00371878 | Completed | Phase 4 | Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Lung Fluid of Adults With and Without HIV Infection | February 2003 | October 2003 |
| NCT00427076 | Completed | Phase 3 | Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections | June 2007 | June 2014 |
| NCT03314779 | Completed | Combined Intracerebral and Jugular Bulb Microdialysis | August 28, 2017 | July 1, 2018 | |
| NCT00119080 | Completed | Phase 4 | Effect of Meningococcal Conjugate Vaccine on Meningococcal Carriage | August 2006 | May 2007 |
| NCT02842853 | Completed | Phase 3 | Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine | July 15, 2016 | February 28, 2017 |
| NCT02842866 | Completed | Phase 3 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Adults 56 Years and Older | July 15, 2016 | February 13, 2017 |
| NCT02858661 | Completed | N/A | Improving the Diagnosis of Meningitis in Emergency Rooms | March 30, 2013 | October 27, 2022 |
| NCT02864927 | Completed | Phase 4 | Postmarketing Surveillance Study for Use of Menactra® in the Republic of Korea | July 21, 2016 | June 12, 2019 |
| NCT02881957 | Completed | Phase 2/Phase 3 | Hypovitaminosis D in Neurocritical Patients | October 10, 2016 | October 10, 2018 |
| NCT02910037 | Completed | N/A | Precision Diagnosis of Acute Infectious Diseases; Neuroinflammatory Cohort | June 1, 2016 | July 31, 2017 |
| NCT02943902 | Completed | Phase 3 | Reduced PCV Dosing Schedules in South African Infants | January 9, 2017 | February 26, 2019 |
| NCT02955797 | Completed | Phase 3 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Toddlers | February 24, 2017 | October 26, 2017 |
| NCT03077438 | Completed | Phase 3 | Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Children Aged 2 to 9 Years | February 17, 2017 | October 10, 2017 |
| NCT03112031 | Completed | Phase 2 | Treatment With Tamoxifen in Cryptococcal Meningitis | October 10, 2017 | July 17, 2018 |
| NCT03205358 | Completed | Phase 2 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Toddlers | March 31, 2015 | August 19, 2015 |
| NCT03206541 | Completed | Neurologic Manifestations of the Arbovirus Infection in Colombia | January 1, 2016 | December 31, 2019 | |
| NCT00002010 | Completed | N/A | Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis | ||
| NCT03378258 | Completed | Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. | November 9, 2017 | June 30, 2019 | |
| NCT03710278 | Completed | The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat) | December 21, 2017 | January 23, 2019 | |
| NCT03796546 | Completed | Pediatric Infectious Disease Precision Medicine Using Sequencing Evaluation of CSF | January 22, 2019 | October 7, 2020 | |
| NCT03826056 | Completed | N/A | Neurology Inpatient Clinical Education Trial | February 1, 2019 | December 7, 2021 |
| NCT03900091 | Completed | Paediatric Infections Point-Of-Care | April 1, 2019 | July 24, 2020 | |
| NCT03967210 | Completed | Epidemiological, Clinical, Microbiological and Outcome Description of Patients With Klebsiella sp Meningitis | July 5, 2019 | January 13, 2020 | |
| NCT04080921 | Completed | Phase 1/Phase 2 | Stem Cell Transplantation In-patient With Neurological Sequelae Due to Encephalitis or Meningitis | June 16, 2014 | August 30, 2019 |
| NCT04275284 | Completed | Persistence of Immunogenicity Following Reduced PCV Dosing Schedules in South African Children | February 14, 2020 | December 1, 2022 | |
| NCT04325685 | Completed | N/A | The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia | January 1, 2020 | November 7, 2023 |
| NCT04794881 | Completed | N/A | Repeat Lumbar Puncture at 24 Versus 48 Hours After Traumatic Lumbar Puncture in Neonates | March 18, 2019 | December 1, 2020 |
| NCT04823026 | Completed | Host RNA Profiles to Detect Infections in Young Infants | May 15, 2020 | December 31, 2021 | |
| NCT05259683 | Completed | Febrile Infant Diagnostic Assessment and Outcome Study | August 1, 2022 | December 31, 2023 | |
| NCT05370573 | Completed | Brazil ICU Encephalitis Surveillance | June 1, 2019 | January 1, 2022 | |
| NCT06334796 | Completed | Early Phase 1 | Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology | October 1, 2023 | January 1, 2024 |
| NCT00459316 | Completed | Phase 1/Phase 2 | Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth | June 2007 | March 2013 |
| NCT00495690 | Completed | Phase 3 | Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease | November 2004 | May 2008 |
| NCT00539032 | Completed | Phase 3 | Immunology and Safety of Menactra® in Children in Saudi Arabia | September 2007 | February 2009 |
| NCT00631995 | Completed | Phase 1 | Safety and Immunogenicity of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Toddlers | April 2008 | April 2009 |
| NCT00643916 | Completed | Phase 2 | Study of a Tetravalent Meningococcal Diphtheria Toxoid Conjugate Vaccine in Toddlers 9 to 18 Months of Age | December 2004 | October 2007 |
| NCT00700635 | Completed | Phase 2 | Dose Comparison Study of Menactra® in US Children | June 2008 | October 2009 |
| NCT00700713 | Completed | Phase 2 | Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study MTA26 | June 2008 | March 2009 |
| NCT00707785 | Completed | Phase 3 | Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis | December 2006 | June 2012 |
| NCT00714402 | Completed | Procalcitonin Level and Kinetics in Children With Bacterial Infections | August 2008 | ||
| NCT00728260 | Completed | 36-Month Post-marketing Surveillance and Analysis of Menactra Vaccine in 2-10 Year Olds | July 2005 | May 2013 | |
| NCT00771849 | Completed | Phase 2 | Study of Antibody Responses After a Dose of Tetravalent Meningococcal Diphtheria Conjugate Vaccine in Children | August 2003 | May 2004 |
| NCT00772070 | Completed | Phase 2 | Study of Reduced Dose of Menomune® in Children Who Previously Received Meningococcal Diphtheria Toxoid Conjugate Vaccine | March 2003 | May 2004 |
| NCT00777257 | Completed | Phase 4 | Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap Vaccine | April 2005 | September 2007 |
| NCT00777790 | Completed | Phase 2 | Study of a Booster Dose of Meningococcal Diphtheria Toxoid Conjugate Vaccine in Adolescents | February 2004 | April 2005 |
| NCT00806195 | Completed | Phase 3 | Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants | December 2008 | November 2011 |
| NCT00850603 | Completed | Phase 4 | Safety and Immunogenicity of Intradermal Versus Subcutaneous Doses of Menomune® | October 2002 | November 2004 |
| NCT00862277 | Completed | Persistence of Bactericidal Antibodies in Adolescents and Adults Who Had Received a Single Dose of Menactra® Vaccine | December 2008 | December 2009 | |
| NCT00901940 | Completed | Phase 3 | Understanding the Immune Response to Meningitis Vaccines | June 2009 | October 2010 |
| NCT01049035 | Completed | Phase 2 | A Study of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Infants and Toddlers | December 16, 2009 | February 13, 2012 |
| NCT01086969 | Completed | Phase 3 | A Study of Meningococcal Vaccine, Menactra® in Healthy Subjects in India | June 2010 | June 2011 |
| NCT01119482 | Completed | Phase 4 | Study on the Impact of Vaccination With a Conjugate Vaccine on Meningococcal Carriage | May 2010 | June 2012 |
| NCT01239043 | Completed | Phase 2 | Antibody Persistence and Response to Re-vaccination With Either Menactra® or Menomune® 3 Years After Initial Vaccination | November 2010 | February 2012 |
| NCT01270503 | Completed | Phase 4 | Post-Marketing Safety Study of Menactra® in Healthy Children, Adolescents, and Adults in the Philippines | December 2010 | July 2014 |
| NCT01323270 | Completed | Phase 2 | A Trial to Assess the Safety, Tolerability and Immunogenicity of Repevax and rLP2086 Vaccine When Given Together in Healthy Subjects Aged >=11 to <19 Years. | March 18, 2011 | February 19, 2013 |
| NCT01359449 | Completed | Phase 3 | Study of Two Doses of Menactra® or One Dose of Monovalent Meningococcal Group C Vaccine With Routine Immunizations | May 2011 | November 2012 |
| NCT01396798 | Completed | Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E. | February 2011 | March 2012 | |
| NCT01430611 | Completed | Phase 4 | Study of Sanofi Pasteur and Lanzhou Institute's Meningococcal (Group A and C) Polysaccharide Vaccine in Children | August 2011 | November 2012 |
| NCT01442675 | Completed | Phase 2 | Study of a Single Dose of Menactra® Vaccine 4-6 Years After Prior Menactra Vaccine | September 2011 | December 2012 |
| NCT01519713 | Completed | Phase 3 | Study of a Single Dose of Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine (SP284) in Japanese Subjects | January 2012 | December 2012 |
| NCT01554124 | Completed | Phase 1/Phase 2 | Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days of Age With Probable and Confirmed Meningitis | February 2013 | December 2014 |
| NCT01580033 | Completed | Phase 3 | Phase 3 Study of A Group A, C Polysaccharide Meningococcal and Type b Haemophilus Influenzal Conjugate Vaccine | April 2012 | November 2012 |
| NCT01593514 | Completed | Phase 4 | Understanding the Immune Response to Two Different Meningitis Vaccines | December 2012 | |
| NCT01642589 | Completed | Phase 3 | Safety and Immunogenicity Study for Use of Menactra® Versus Adacel® in Subjects 11 to 55 Years of Age in South Korea | July 2012 | June 2013 |
| NCT01659996 | Completed | Phase 4 | Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age | July 2012 | September 2015 |
| NCT01661725 | Completed | Phase 1 | Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 001 | April 2006 | May 2006 |
| NCT01661738 | Completed | Phase 2 | Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 002 | May 2006 | June 2006 |
| NCT01661751 | Completed | Phase 3 | Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 003 | May 2006 | August 2006 |
| NCT01689155 | Completed | Post-licensure Safety Surveillance Study of Menactra Vaccine When Administered As a 2-dose Schedule to Children | June 2011 | April 2016 | |
| NCT01694524 | Completed | Nervous System Infections Among Patients With Febrile Seizure | June 2013 | March 2014 | |
| NCT01732627 | Completed | Phase 2 | Study of a Quadrivalent Meningococcal Conjugate Vaccine in Subjects Aged 56 and Older | November 12, 2012 | January 17, 2013 |
| NCT01745679 | Completed | Phase 4 | Pharmacological Study of High Doses of Ceftriaxone in Meningitidis | December 2012 | December 2015 |
| NCT01890759 | Completed | Phase 3 | Immunogenicity and Safety of Menactra® Vaccine in Subjects Aged 9 to 23 Months in India and in the Russian Federation | June 25, 2013 | April 12, 2016 |
| NCT01996007 | Completed | Understanding Pneumococcal Carriage and Disease | March 2014 | August 2015 | |
| NCT02003313 | Completed | Phase 3 | Immunogenicity and Safety of Group A, C, Y and W135 Meningococcal Polysaccharide Vaccine | November 2013 | July 2015 |
| NCT02003495 | Completed | Phase 3 | Immunogenicity and Safety of Meningococcal (A, C, Y and W135) Conjugate Vaccine | October 2013 | October 2014 |
| NCT02024282 | Completed | N/A | Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care | January 2013 | December 2014 |
| NCT02054091 | Completed | N/A | Feeding Bovine Colostrum to Preterm Infants | February 2014 | January 2017 |
| NCT02080559 | Completed | Phase 4 | Investigating the Immune Response to 4CMenB in Infants | July 21, 2014 | April 27, 2018 |
| NCT02199691 | Completed | Phase 2 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adolescents | July 22, 2014 | October 2, 2015 |
| NCT02526394 | Completed | Phase 4 | Pertussis and Meningitis C Concomitant Vaccination in Adolescents | September 2013 | March 31, 2017 |
| NCT02591290 | Completed | Phase 4 | Immunogenicity and Safety of Two-Dose Series of Menactra® in Japanese Healthy Adult Subjects | October 20, 2015 | March 16, 2016 |
| NCT02633787 | Completed | Phase 4 | Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Years Earlier | December 2015 | March 2016 |
| NCT02640404 | Completed | Phase 2 | Safety of a Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Healthy Subjects in Vietnam | June 6, 2016 | December 5, 2016 |
| NCT02699840 | Completed | Observational Safety Study of Menactra® Administered Under Standard Health Care Practice in the Russian Federation | February 2016 | July 25, 2016 | |
| NCT02752906 | Completed | Phase 3 | Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccine | April 15, 2016 | December 19, 2016 |
| NCT02806284 | Completed | Phase 2 | Pneumococci and Hib Vaccination After Neurotrauma or Neurosurgery | January 2001 | January 2010 |
| NCT02806882 | Completed | Phase 1 | Penetration of Ceftaroline Into Cerebrospinal Fluid(CSF) | April 29, 2015 | October 24, 2016 |
| NCT02841254 | Completed | Diagnostic Performance of Clinical Signs Patients Suspected of Meningitis to Emergencies | November 2014 | May 2016 | |
| NCT04722328 | Not yet recruiting | Establishment of Prevention and Control System of Central Nervous System Infection | March 1, 2021 | December 31, 2025 | |
| NCT06075732 | Not yet recruiting | N/A | ACTIVATE in Public Housing | July 1, 2024 | December 31, 2029 |
| NCT03418441 | Recruiting | Central Nervous System Infections in Denmark | January 1, 2015 | January 1, 2030 | |
| NCT06283901 | Recruiting | Improving Diagnosis and Prediction of Outcome in Patients With Severe Disorders of Consciousness | January 2, 2023 | September 1, 2025 | |
| NCT04664569 | Recruiting | National Bacterial Meningitis Study | January 1, 2001 | January 1, 2030 | |
| NCT03840928 | Recruiting | PatientSpot Formerly Known as ArthritisPower | April 1, 2015 | March 1, 2025 | |
| NCT00901602 | Recruiting | Lebanese Interhospital Pneumococcal Surveillance Program | October 2005 | October 2030 | |
| NCT05393492 | Recruiting | N/A | Regulating Emotions and Behaviors After Brain Injury | May 19, 2022 | December 2025 |
| NCT05637645 | Recruiting | N/A | Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section | November 22, 2022 | January 31, 2023 |
| NCT05496673 | Recruiting | N/A | Meningitis: Burden, Causes, Screening and Prevention in Rural Northern Uganda | September 1, 2022 | September 1, 2027 |
| NCT00772629 | Terminated | Phase 2 | Antibody Responses Following Meningococcal Tetravalent (A, C, Y, and W-135) Conjugate Vaccination in Healthy Adults | January 2004 | April 2004 |
| NCT01366651 | Terminated | Phase 1 | A Study of Doripenem in CerebrospinalFluid After Doripenem Administration in Pediatric Patients Less Than 1 Year of Age | March 2012 | June 2012 |
| NCT01522105 | Terminated | Phase 1 | Daptomycin in Pediatric Patients With Bacterial Meningitis | April 2012 | June 30, 2018 |
| NCT00074607 | Terminated | Phase 1 | Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine | December 2001 | April 2007 |
| NCT00428051 | Terminated | Colombia Epidemiologic Surveillance Study | September 2006 | October 2011 | |
| NCT01606150 | Terminated | N/A | Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain | November 2012 | July 2014 |
| NCT00317382 | Terminated | N/A | Does Static Ultrasound-Preview Reduce the Incidence of Difficult Lumbar Puncture? | December 2004 | October 2005 |
| NCT00927953 | Terminated | Phase 2 | Treatment of West Nile Virus With MGAWN1 | May 2009 | May 2011 |
| NCT01025271 | Terminated | N/A | Cerebrospinal Fluid Pharmacokinetics of Daptomycin | May 2010 | May 2011 |
| NCT05062642 | Unknown status | Validation of a Predictive Rule for the Diagnosis of Viral Meningitis in Adult Emergency Departments | August 26, 2021 | August 26, 2022 | |
| NCT04946682 | Unknown status | N/A | Optimal Encephalitis/Meningitis Roadmap Via Precise Diagnosis and Treatment | April 14, 2021 | April 30, 2023 |
| NCT03746665 | Unknown status | Phase 3 | Maternal Immunization With MenAfriVac™ | December 19, 2018 | August 2021 |
| NCT01619462 | Unknown status | Phase 3 | Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children | November 2011 | November 2016 |
| NCT02919293 | Unknown status | Phase 1/Phase 2 | Immunogenicity and Safety of Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine in Infants 2 to 5 Months of Age | August 2016 | May 2017 |
| NCT04917380 | Unknown status | The Clinical Character，Risk and Prognosis of Post-neurosurgical Intracranial Infection With Different Pathogens. | June 10, 2021 | October 30, 2021 | |
| NCT03445416 | Withdrawn | N/A | Increasing Healthcare Engagement Via Routine Vaccination Among Young Black Men Who Have Sex With Men | September 2018 | August 2020 |
| NCT02727465 | Withdrawn | Host-pathogen Interactions in Meningococcal Disease: Finding the Key That Fits the Lock | March 2016 | December 2019 |
- Disase is a (Disease Ontology)
- DOID:331
- Cross Reference ID (Disease Ontology)
- ICD10CM:G03
- Cross Reference ID (Disease Ontology)
- ICD9CM:322.9
- Cross Reference ID (Disease Ontology)
- MESH:D008581
- Cross Reference ID (Disease Ontology)
- NCI:C26828
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154983000
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0025289
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001287
- MeSH unique ID (MeSH (Medical Subject Headings))
- D008581