Necrotizing Enterocolitis
Information
- Disease name
- Necrotizing Enterocolitis
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03554278 | Active, not recruiting | Alteration of Stool Microbiota in Preterm Infants With Anemia | October 9, 2018 | October 31, 2024 | |
| NCT06202911 | Active, not recruiting | Phase 4 | Effect of Oral N-Acetyl Cysteine in Prevention of Necrotizing Enterocolitis in Preterm Neonates With Feeding Intolerance | January 1, 2023 | March 30, 2024 |
| NCT03797157 | Active, not recruiting | Phase 2/Phase 3 | Human Milk Fortification in Extremely Preterm Infants | February 1, 2019 | December 31, 2027 |
| NCT03717584 | Active, not recruiting | A Cohort Study of the Intestinal Microbiota of Premature Infants | December 23, 2018 | December 2026 | |
| NCT03978000 | Active, not recruiting | Phase 3 | IBP-9414 for the Prevention of Necrotizing Enterocolitis - The Connection Study | July 4, 2019 | July 2024 |
| NCT00315263 | Completed | Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology | April 2006 | July 2011 | |
| NCT00332592 | Completed | Intragastric and Peritoneal Microdialysis in Infants With Necrotizing Enterocolitis (NEC) | October 2006 | May 2010 | |
| NCT00392730 | Completed | Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children | August 2006 | December 2010 | |
| NCT00392977 | Completed | Brain Manganese Deposition in High Risk Neonates | August 2006 | December 2010 | |
| NCT00005888 | Completed | N/A | Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants | January 1997 | |
| NCT05033639 | Completed | Phase 1/Phase 2 | Efficacy Of Oral Melatonin To Prevent Necrotizing Enterocolitis | March 1, 2021 | December 31, 2021 |
| NCT00616876 | Completed | Phase 2 | Lactulose Supplementation in Premature Infants | February 2005 | January 2007 |
| NCT00621192 | Completed | Phase 1/Phase 2 | Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections | June 2008 | October 2009 |
| NCT00707785 | Completed | Phase 3 | Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis | December 2006 | June 2012 |
| NCT00787124 | Completed | Transfusions and Nitric Oxide Level in Preterm Infants | September 2008 | September 2009 | |
| NCT00828451 | Completed | N/A | Collaborative Research Group for Necrotizing Enterocolitis | May 2008 | December 2010 |
| NCT04344639 | Completed | Incidence, Risk Factors, Severity and Prognosis of Necrotizing Enterocolitis in Turkey | March 1, 2019 | April 1, 2020 | |
| NCT00840983 | Completed | Phase 1 | Effects of Delayed Cord Clamping in Very Low Birth Weight Infants | August 2003 | December 2006 |
| NCT04304807 | Completed | Phase 4 | Effect of Melatonin on Feeding Intolerance and Incidence of Necrotizing Enterocolitis in Preterm Infants | December 24, 2018 | December 31, 2019 |
| NCT04077333 | Completed | N/A | MISA to NRDS：a Multicenter Study in China | July 1, 2017 | March 30, 2019 |
| NCT04020939 | Completed | N/A | The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. | March 16, 2020 | March 10, 2021 |
| NCT01102738 | Completed | Defining the Intestinal Microbiota in Premature Neonates | January 2011 | June 2014 | |
| NCT03994341 | Completed | NEC Thermography Infrared Imaging Study | August 13, 2019 | April 2, 2020 | |
| NCT01126372 | Completed | Prediction of Feeding Problems in Prostaglandin-dependent Prematurely Born Infants With Congenital Heart Disease | May 2010 | June 2013 | |
| NCT01222585 | Completed | Phase 1 | Metronidazole Pharmacokinetics (PK) in Premature Infants | January 2011 | November 2011 |
| NCT03822104 | Completed | N/A | Bovine Colostrum as a Human Milk Fortifier for Preterm Infants | May 1, 2019 | July 8, 2021 |
| NCT01306838 | Completed | Early Phase 1 | Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy | October 2009 | October 2014 |
| NCT03643458 | Completed | Splanchnic Oxygenation Response to Feeds in Preterm Neonates: Effect of Red Blood Cell Transfusion | June 1, 2013 | June 30, 2014 | |
| NCT01340469 | Completed | Phase 3 | Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants | January 2005 | June 2008 |
| NCT01441427 | Completed | Phase 1/Phase 2 | Enteral Granulocyte Colony Stimulating Factor and Erythropoietin Early in Life Increases Feeding Tolerance in Preterm Infants: A Randomized Controlled Trial | January 2010 | August 2011 |
| NCT03551600 | Completed | Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus | October 2015 | June 30, 2022 | |
| NCT03537365 | Completed | N/A | Bovine Colostrum as a Fortifier Added to Human Milk for Preterm Infants | December 4, 2017 | February 28, 2022 |
| NCT01531179 | Completed | Phase 3 | Lactobacillus Reuteri for Prevention of Necrotizing Enterocolitis in Very Low-birth Weight Infants | February 2012 | February 2013 |
| NCT01603368 | Completed | Phase 2 | Prophylactic Probiotics to Extremely Low Birth Weight Prematures | June 2012 | December 2015 |
| NCT01670916 | Completed | Probiotics to Prevent NEC - a Historical Control Study | March 2010 | June 2013 | |
| NCT01727609 | Completed | N/A | Speed of Increasing Milk Feeds Trial | June 2013 | May 10, 2018 |
| NCT03278847 | Completed | Optimising Newborn Nutrition During Therapeutic Hypothermia. | January 1, 2010 | January 1, 2021 | |
| NCT01735578 | Completed | Splanchnic Tissue Oxygenation During Enteral Feedings in Anemic Premature Infants at Risk for Necrotizing Enterocolitis | October 2012 | April 2015 | |
| NCT01745510 | Completed | Phase 1/Phase 2 | Enteral Administration of Docosahexaenoic Acid to Prevent Necrotizing Enterocolitis in Preterm Neonates | October 2012 | October 2017 |
| NCT01751477 | Completed | Infloran® for Prevention of Necrotizing Enterocolitis | September 2010 | October 2012 | |
| NCT03258957 | Completed | N/A | Pilot Study of the Feasibility of Feeding Preterm Infants With Fresh Versus Frozen Mother's Own Breast Milk in the NICU | January 1, 2016 | December 31, 2017 |
| NCT03085277 | Completed | N/A | Bovine Colostrum for Preterm Newborns | July 1, 2017 | November 18, 2020 |
| NCT02650869 | Completed | Phase 3 | Role of Probiotics for Prevention of NEC in Preterm VLBW Infants | July 2012 | December 2015 |
| NCT01868737 | Completed | Phase 3 | Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature Infants | July 2011 | August 2012 |
| NCT01954017 | Completed | Phase 1 | STP206 for the Prevention of Necrotizing Enterocolitis (NEC) | January 30, 2014 | October 22, 2018 |
| NCT01958320 | Completed | Phase 2 | Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus | December 2013 | June 2017 |
| NCT02472769 | Completed | Phase 2 | IBP-9414 for the Prevention of Necrotizing Enterocolitis | May 27, 2016 | August 7, 2017 |
| NCT02054091 | Completed | N/A | Feeding Bovine Colostrum to Preterm Infants | February 2014 | January 2017 |
| NCT02073214 | Completed | N/A | Effects of Oral Probiotic Supplementation on the Clinical Status of Very-low-birth-weight Preterm Neonates. | April 2012 | December 2013 |
| NCT02347475 | Completed | SMA Flow Patterns in Neonatal Transfusion | January 2015 | December 2017 | |
| NCT02383264 | Completed | Splanchnic Oxygenation After the First Enteral Feed in Preterm Infants: Prediction of Feeding Tolerance. | February 2013 | March 2015 | |
| NCT02444624 | Completed | Clostridium and Neonatal Necrotizing Enterocolitis Pathophysiology : Clinical and Molecular Approaches | May 28, 2015 | September 13, 2019 | |
| NCT02400697 | Completed | Placental Transfusion Project for Preterm Infants | September 2014 | December 2016 | |
| NCT00059449 | Completed | Role of Epidermal Growth Factor (EGF) in Development of Necrotizing Enterocolitis | |||
| NCT06422000 | Completed | Phase 3 | Effect of Pentoxifylline Versus Probiotic on Preterm Neonates With Necrotizing Enterocolitis | June 30, 2022 | December 30, 2023 |
| NCT00252681 | Completed | N/A | Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants | July 1999 | June 2005 |
| NCT05311228 | Completed | Phase 4 | The Efect of Azithromicyn on Bronchopulmonary Displasia in Extremely Preterm and Very Preterm Infant | June 8, 2021 | April 1, 2022 |
| NCT05228847 | Not yet recruiting | N/A | Human Milk-derived Fortification in Preterm Infants | January 15, 2023 | May 30, 2025 |
| NCT04696003 | Not yet recruiting | Phase 3 | Treatment of Classic Mid-trimester PPROM by Means of Continuous Amnioinfusion | January 1, 2021 | May 30, 2025 |
| NCT06045130 | Not yet recruiting | PUFAs in Preterm Infants | September 21, 2023 | August 31, 2026 | |
| NCT06118801 | Not yet recruiting | N/A | The Effect of Probiotics Added to the Mother's Diet on Preterm Babies | November 2023 | March 2024 |
| NCT06319326 | Not yet recruiting | Intestinal Perfusion After Feeding in Preterm and Term Infants | April 2, 2024 | August 31, 2024 | |
| NCT06333405 | Not yet recruiting | N/A | Fecal Microbiota Transplantation (FMT) as a Prophylaxis of Necrotizing Enterocolitis (NEC) - Clinical Study | May 1, 2024 | January 31, 2025 |
| NCT04584320 | Recruiting | Identification of Clostridium Butyricum and Clostridium Neonatal in the Digestive Microbiota of Premature Infants Before 34 Weeks and Developing or Not Ulcerative Necrotizing Enterocolitis (NEC) During Hospitalization | October 18, 2021 | October 2025 | |
| NCT05604846 | Recruiting | N/A | Probiotic Supplementation in Extremely Preterm Infants in Scandinavia | December 16, 2022 | December 2026 |
| NCT04074824 | Recruiting | A Genome-Wide Association Study for Neonatal Diseases | September 1, 2018 | October 31, 2024 | |
| NCT04284280 | Recruiting | N/A | Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants | February 15, 2020 | February 1, 2027 |
| NCT03210831 | Recruiting | Early Predictors of Necrotizing Enterocolitis in Neonates | September 6, 2017 | December 2026 | |
| NCT05573113 | Recruiting | N/A | Comparative Effectiveness Trial for Diagnosis of Necrotizing Enterocolitis | November 1, 2022 | December 31, 2025 |
| NCT05544097 | Recruiting | N/A | Spectral Analysis of Bowel Sounds in Preterm Babies of Less Than 32 Weeks of Amenorrhea (WA) as Predictive Factor of Enterocolitis | September 6, 2022 | November 2025 |
| NCT06315738 | Recruiting | Phase 1/Phase 2 | Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis | May 29, 2024 | August 2027 |
| NCT05279664 | Recruiting | Phase 2 | RIC-NEC Randomized Controlled Trial | February 9, 2023 | May 1, 2027 |
| NCT06032676 | Recruiting | Qualitative Study of Surgeons With Prospective Patient Follow-up | January 1, 2024 | October 1, 2028 | |
| NCT05272579 | Recruiting | Early Phase 1 | PrePhage - Faecal Bacteriophage Transfer for Enhanced Gastrointestinal Tract Maturation in Preterm Infants | November 7, 2023 | December 31, 2024 |
| NCT05213806 | Recruiting | N/A | WithHolding Enteral Feeds Around Blood Transfusion (International) | January 28, 2022 | December 31, 2025 |
| NCT04972734 | Recruiting | N/A | Cohort of Premature Newborns for Charaterization of the Digestive Microbiota in Ulcerative Necrotizing Enterocolitis in Premature Infants | July 2, 2021 | January 1, 2025 |
| NCT04912453 | Recruiting | N/A | Primary Anastomosis Versus Enterostomy in the Surgical Treatment of Necrotising Enterocolitis | July 1, 2021 | January 31, 2025 |
| NCT04801537 | Recruiting | Temperature of Extremities and Necrotizing Enterocolitis | January 1, 2021 | December 31, 2024 | |
| NCT04795453 | Recruiting | Assessment of Score System of Surgery in Necrotizing Enterocolitis(NEC) Patients | March 1, 2021 | December 31, 2024 | |
| NCT03631979 | Recruiting | N/A | Intestinal Lavage to Promote Enteral Feeding and Prevent Necrotizing Enterocolitis in Extremely Preterm Infants | August 15, 2018 | November 2031 |
| NCT01106209 | Suspended | Neutrophil Extracellular Trap Formation in Newborn Infants at Risk for Inflammatory Syndromes | April 2010 | March 31, 2023 | |
| NCT06035848 | Terminated | N/A | Components of Metabolic Derangement and Paracentesis for Determination of Surgery in Preterm Neonates With Necrotizing Enterocolitis. | February 1, 2022 | June 30, 2023 |
| NCT01735552 | Terminated | Transfusion-related Inflammatory Cytokine and Neutrophil Extracellular Trap Quantification in Neonates | June 2012 | April 2015 | |
| NCT03320785 | Terminated | Circulating Markers in Preterm Infants With Perinatal and Neonatal Inflammation | September 1, 2017 | December 31, 2021 | |
| NCT01330576 | Terminated | N/A | Therapeutic Controlled Hypothermia in the Treatment of Neonates With Severe Necrotizing Enterocolitis | August 2, 2010 | March 25, 2013 |
| NCT01156480 | Terminated | N/A | Anti-inflammatory Treatment at the Onset of Necrotizing Enterocolitis (NEC) in Preterm Infants | September 2009 | November 2012 |
| NCT01062828 | Terminated | Defining Normal Citrulline Levels as a Diagnostic Tool for Screening of Gastrointestinal Disease in Premature Infants | July 2009 | July 2017 | |
| NCT01062815 | Terminated | N/A | Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants | February 2009 | June 2010 |
| NCT00977912 | Terminated | N/A | Necrotizing Enterocolitis (Nec) and B. Lactis in Premature Babies | November 2009 | September 2013 |
| NCT00835874 | Terminated | N/A | Probiotic Administartion to Mothers of Preterm Infants to Prevent Necrotizing Enterocolitis and Sepsis | June 2007 | July 2009 |
| NCT01315821 | Unknown status | Phase 3 | Effect of Saccharomyces Boulardii on Necrotizing Enterocolitis in Very Low Birth Weight Infants | February 2011 | December 2011 |
| NCT03700957 | Unknown status | N/A | The Impact of Docosahexaenoic Acid on the Prevention of Necrotizing Enterocolitis in Preterm Neonates | October 2018 | September 2019 |
| NCT02552706 | Unknown status | N/A | The Efficacy and Mechanisms of Oral Probiotics in Preventing Necrotizing Enterocolitis | September 2014 | September 2017 |
| NCT01855347 | Unknown status | Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy | February 2016 | July 2016 | |
| NCT04541771 | Unknown status | Phase 2 | The Role of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis (NEC) in Pre-term Infants | October 2020 | January 2021 |
| NCT01336998 | Unknown status | N/A | Administration of Arginine Supplementation in Preterm Infants | June 2009 | |
| NCT00254176 | Unknown status | Phase 2/Phase 3 | Cysteine Supplementation in Critically Ill Neonates | September 2006 | July 2011 |
| NCT03593252 | Unknown status | N/A | Bowel Preparation in Elective Pediatric Colorectal Surgery | January 1, 2022 | January 30, 2024 |
| NCT03578978 | Unknown status | A Panel of Biomarkers in Diagnosing Late-onset Neonatal Sepsis and Necrotizing Enterocolitis in Sibu Hospital | July 1, 2018 | August 31, 2021 | |
| NCT02405637 | Unknown status | Phase 1 | Simulated Amniotic Fluid In Preventing Feeding Intolerance and Necrotizing Enterocolitis VLBW Neonates | March 2014 | May 2015 |
| NCT01287559 | Unknown status | Monitoring Necrotizing Enterocolitis in Premature Infants | March 2011 | ||
| NCT02050971 | Unknown status | Phase 1 | Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonates | October 2010 | December 2015 |
| NCT02534090 | Unknown status | Evaluation of Feeding Intolerance in Premature Infants Using Near Infrared Spectroscopy | November 2015 | March 2016 | |
| NCT01441739 | Unknown status | Intestinal Failure in Necrotising Enterocolitis | September 2004 | September 2016 | |
| NCT00588718 | Unknown status | A Biologic Validation of Biomarkers of Progressive NEC & Sepsis | April 2007 | December 2019 | |
| NCT05121753 | Unknown status | Infant Formula Feeding and Necrotizing Enterocolitis in Newborns | February 15, 2022 | January 15, 2024 | |
| NCT01530828 | Unknown status | IRT in Infants With Intestinal Perforation | August 2010 | August 2014 | |
| NCT00437567 | Unknown status | Phase 2 | Prebiotics in the Prevention of Necrotizing Enterocolitis | July 2009 | July 2014 |
| NCT03431558 | Unknown status | Phase 3 | Bovine Lactoferrin and Neonatal Survival in Low Birth Weight Babies. | May 1, 2018 | May 2020 |
| NCT03302338 | Unknown status | Phase 1 | Simulated Amniotic Fluid Solution in Neonates Recovering From GIT Surgeries | July 2015 | October 2018 |
| NCT00271336 | Unknown status | Phase 2 | Pentoxifylline in the Treatment of NEC in Premature Neonates | January 2005 | March 2010 |
| NCT03257553 | Unknown status | N/A | Ultrasound, Doppler ,and Calprotectin in Necrotizing Enterocolitis Diagnosis | April 2018 | April 2019 |
| NCT01807858 | Unknown status | N/A | The Effects of Synbiotics on Morbidity and Mortality in Preterm Infants | October 2012 | December 2013 |
| NCT02796703 | Unknown status | Phase 2 | Heat Killed Probiotics in the Prevention of Necrotizing Enterocolitis | June 2016 | September 2020 |
| NCT02733718 | Unknown status | N/A | The Impact of Different Feeding Strategies During Packed Red Cell Transfusion on Intestinal Oxygenation | November 2015 | September 2017 |
| NCT02741648 | Unknown status | RBC Irradiation, Anemia and Gut Injury | July 2016 | April 2022 | |
| NCT00120159 | Unknown status | Necrotizing Enterocolitis (NEC) Surgical Database | December 2003 | ||
| NCT03869827 | Unknown status | Necrotizing Enterocolitis in Fetuses With Intrauterine Growth Restriction | September 1, 2018 | April 1, 2019 | |
| NCT01337921 | Withdrawn | N/A | A Multi-strain Synbiotic Versus a Multi-strain Probiotic in Premature Infants | June 2011 | June 16, 2011 |
| NCT04921696 | Withdrawn | Association of Red Blood Cell Transfusion, Anemia, and Necrotizing Enterocolitis | July 1, 2021 | December 31, 2026 | |
| NCT05055817 | Withdrawn | a Clinical Risk Score to Predict Bloody Stool in Neonates | October 1, 2021 | December 31, 2024 | |
| NCT01805206 | Withdrawn | Phase 2 | Prediction of NEC With Urinary iFABP | November 2014 | July 2016 |