depressive disorder
Information
- Disease name
- depressive disorder
- Disease ID
- DOID:1596
- Description
- "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function." [url:https\://my.clevelandclinic.org/health/diseases/9290-depression, url:https\://pubmed.ncbi.nlm.nih.gov/31550874/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05812443 | Active, not recruiting | N/A | Assessment of Sleep Quality and Mental Health After Using Meditation | April 10, 2023 | March 2024 |
| NCT04513080 | Active, not recruiting | N/A | Message-Based Psychotherapy and Digital Treatment Sequences for Depression | March 2, 2020 | August 31, 2024 |
| NCT04427579 | Active, not recruiting | Anxiety and Depression in COPD; Prevalence, Detection and Prognosis | June 15, 2018 | December 2025 | |
| NCT05211466 | Active, not recruiting | Digital Care Chains in Health Care - a Study of Care Consumption, Care Quality, Work Environment and Well-being | January 17, 2022 | November 1, 2025 | |
| NCT05574491 | Active, not recruiting | N/A | Effectiveness of Traditional and Computerized Versions of Super Skills for Life in Children | February 7, 2023 | December 31, 2024 |
| NCT04162847 | Active, not recruiting | N/A | Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations | October 7, 2019 | December 2024 |
| NCT06234371 | Active, not recruiting | N/A | Financial Incentives for Veteran Therapy Completion | January 2, 2024 | January 2, 2028 |
| NCT05095662 | Active, not recruiting | Establish a Specific Cohort Database for Depressive Disorders | June 1, 2021 | December 31, 2026 | |
| NCT04016402 | Active, not recruiting | Imaging to Improve Brain Stimulation | October 24, 2019 | September 30, 2024 | |
| NCT03674138 | Active, not recruiting | N/A | Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients | September 12, 2018 | October 2, 2024 |
| NCT05923476 | Active, not recruiting | Early Phase 1 | Electroconvulsive Therapy and Concomitant Lithium in Depressive Disorder: A Pilot Study | June 1, 2023 | June 30, 2025 |
| NCT04893447 | Active, not recruiting | N/A | Suicide Prevention Among Recipients of Care | May 20, 2021 | July 16, 2024 |
| NCT03250026 | Active, not recruiting | N/A | Cooperation for Primary Care Patients on Sick Leave for CMD: Care Manager and Workplace Intervention - CO-WORK-CARE | December 5, 2017 | December 31, 2024 |
| NCT04777006 | Active, not recruiting | Phase 4 | Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform | September 1, 2021 | June 30, 2025 |
| NCT03096886 | Active, not recruiting | N/A | Novel Neural Circuit Biomarkers of Major Depression Response to CCBT | June 5, 2017 | October 23, 2024 |
| NCT05543265 | Active, not recruiting | N/A | Bridging the Gap From Postpartum to Primary Care | November 3, 2022 | June 2024 |
| NCT00057642 | Completed | N/A | Improving Retention of Hispanics Receiving Antidepressant Therapy | September 2002 | August 2006 |
| NCT00069459 | Completed | Phase 1 | Seasonal Affective Depression (SAD) Study | September 23, 2003 | June 3, 2004 |
| NCT00070694 | Completed | Phase 2 | An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression | September 2003 | October 2004 |
| NCT00071110 | Completed | Phase 2 | Electroacupuncture for Major Depression | March 2004 | May 2007 |
| NCT00073359 | Completed | Phase 1/Phase 2 | Effects of Therapist Behavior on the Treatment of Depressed Adolescents | February 2003 | November 2005 |
| NCT00092911 | Completed | Phase 3 | Study Evaluating DVS-233 SR in Adult Outpatients With Major Depressive Disorder | May 2005 | |
| NCT00096798 | Completed | Phase 3 | Ethyl Eicosapentanoic Acid (Ethyl-EPA) for Treating Major Depression | September 2001 | August 2007 |
| NCT00135512 | Completed | Phase 2 | Study Of 323U66 SR In Major Depressive Disorder | December 1, 2004 | May 28, 2007 |
| NCT00184379 | Completed | N/A | Effects of Psychoeducation of Relatives to Patients With Serious Mental Illness | April 2005 | June 2010 |
| NCT00184418 | Completed | The Immune System and Psychiatric Disorders | January 2005 | January 2008 | |
| NCT00185575 | Completed | N/A | Duloxetine for the Treatment of Dysthymia | September 2004 | April 2006 |
| NCT00191061 | Completed | Phase 4 | A Comparison of Tolerability and Efficacy of Different Doses of Duloxetine for the Treatment of Major Depressive Disorder | October 2004 | January 2006 |
| NCT00202462 | Completed | N/A | The Effect of Testosterone on Mood and Quality of Life | November 2002 | November 2006 |
| NCT00214682 | Completed | Phase 2 | Beyond Ageing Project: A Study for the Prevention of Depression | October 2005 | January 2011 |
| NCT00223652 | Completed | Phase 2 | Telephone Administered Psychotherapy for the Treatment of Depression for Veterans in Rural Areas | March 2006 | April 2010 |
| NCT00250601 | Completed | Phase 3 | An Eight-week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression | April 2005 | July 2007 |
| NCT00250614 | Completed | Phase 3 | An Eight-week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression | April 2005 | October 2006 |
| NCT00250627 | Completed | Phase 3 | An Eight-Week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression | December 2004 | December 2006 |
| NCT00250653 | Completed | Phase 3 | A Fifty-two-week Study to Evaluate the Safety of Saredutant in Adult and Elderly Patients With Depression | May 2005 | April 2007 |
| NCT00253071 | Completed | N/A | Early Integrated Intervention in Severe Affective Disorders | December 2005 | March 2012 |
| NCT00256113 | Completed | Phase 3 | An Eight-week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression | December 2004 | December 2006 |
| NCT00264628 | Completed | GW679769 In Fibromyalgia | October 2005 | September 2006 | |
| NCT00285740 | Completed | N/A | Group Cognitive Behavioral Therapy to Treat Depression in an Epilepsy Clinic Setting | August 2005 | January 2007 |
| NCT00285831 | Completed | Mild Depression 2 Week Observational Study | December 2005 | March 2009 | |
| NCT00296517 | Completed | Phase 3 | Study In Patients With Depression Not Responding to Selective Serotonin Re-uptake Inhibitors | January 19, 2006 | March 28, 2008 |
| NCT00299403 | Completed | Phase 2/Phase 3 | The Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation (rTMS)Compared to ECT | May 2002 | May 2007 |
| NCT00304161 | Completed | Phase 4 | Effectiveness of Antidepressant Treatment for Depression in People With Parkinson's Disease | July 2004 | December 2008 |
| NCT00319319 | Completed | Phase 2 | Nicotinic Receptor Augmentation of SSRI Antidepressants | January 2003 | January 2007 |
| NCT00319709 | Completed | Phase 3 | An Eight-Week Study to Evaluate the Efficacy and Safety of SR58611A in Elderly Patients With Depression | April 2006 | August 2007 |
| NCT00336713 | Completed | Phase 3 | A 24-52-week Study to Evaluate the Long-term Efficacy and Safety of Saredutant in Patients With Depression (MAGENTA) | May 2006 | April 2008 |
| NCT00344682 | Completed | Phase 4 | Memantine Augmentation of Antidepressants | June 2006 | December 2011 |
| NCT00345098 | Completed | Phase 3 | A Study of SR58611A in the Prevention of Depression Relapse in Patients With Major Depressive Disorder | May 2006 | February 2008 |
| NCT00358631 | Completed | Phase 2 | An Eight-Week Study Evaluating the Efficacy and Tolerability of Two Doses of SSR149415 in Outpatients With Major Depressive Disorder | July 2006 | December 2007 |
| NCT00361491 | Completed | Phase 2 | An Eight-Week Study Evaluating the Efficacy of Two Fixed Doses (250 mg Twice Daily and 100 mg Twice Daily) of SSR149415 in Patients With Major Depressive Disorder | August 2006 | September 2007 |
| NCT00366652 | Completed | Phase 3 | Study Evaluating the Effects of DVS SR and Duloxetine on the Pharmacokinetics of Desipramine in Healthy Subjects | September 2006 | September 2006 |
| NCT00369343 | Completed | Phase 3 | Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women | September 2006 | July 2008 |
| NCT00406003 | Completed | Phase 1 | Single Dose Pharmacokinetic (PK) Study Of Paroxetine CR(12.5-37.5mg) In Healthy Chinese Subjects | March 24, 2006 | April 26, 2006 |
| NCT00406432 | Completed | Phase 1 | A Repeat Dose Pharmacokinetic Study Of Paroxetine CR Tablet In Healthy Chinese Subjects | May 9, 2006 | June 2, 2006 |
| NCT00406640 | Completed | Phase 3 | Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) vs. Escitalopram in Postmenopausal Women | December 2006 | October 2008 |
| NCT00415142 | Completed | Phase 3 | An Eight-week Study Evaluating the Efficacy of a 100mg Dose of Saredutant Once Daily, in Elderly Patients With Major Depressive Disorder | December 2006 | February 2008 |
| NCT00419471 | Completed | Phase 4 | Escitalopram in Depressive Patients With Acute Coronary Artery Syndrome | May 2007 | March 2013 |
| NCT00420641 | Completed | Phase 2 | MDD POC Study GSK372475 Subjects Depressive Disease | December 19, 2006 | October 15, 2008 |
| NCT00429260 | Completed | Phase 3 | A Study Evaluating the Safety and Tolerability of Abrupt Discontinuation of Saredutant in Patients With Depression | January 2007 | June 2007 |
| NCT00437827 | Completed | N/A | rEEG Guided Pharmacotherapy of Subjects With Depression Treatment Failure | August 2006 | October 2009 |
| NCT00438685 | Completed | Phase 1 | Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders | October 2004 | September 2010 |
| NCT00439868 | Completed | Phase 1 | A Study To Evaluate The Effect Of WELLBUTRIN XL On Intraocular Pressure | February 16, 2007 | June 8, 2007 |
| NCT00448058 | Completed | Phase 2 | A Study Of New Medicine (GSK 372475) For The Treatment Of Depression | April 2007 | December 2008 |
| NCT00488098 | Completed | Phase 1 | GSK372475 Bioequivalence Study | July 2007 | |
| NCT00511654 | Completed | Phase 1 | 28-day Repeat Dose and Drug Interaction Study With Orvepitant (GW823296) | June 12, 2007 | January 11, 2008 |
| NCT00520507 | Completed | Phase 4 | An Investigation of the Sleep Architecture and Consequent Cognitive Changes in Olanzapine-Treated Depressed Patients | October 2007 | May 2009 |
| NCT00525837 | Completed | N/A | Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient Smokers | September 2007 | March 2008 |
| NCT00551083 | Completed | N/A | Efficacy Study of a Computer Decision Support System to Treat Depression | March 2005 | June 2006 |
| NCT00606996 | Completed | Phase 2 | Group Therapy for Women Prisoners With Comorbid Substance Use and Depression | July 2006 | December 2009 |
| NCT00618865 | Completed | N/A | Omega-3 Fatty Acids for Major Depressive Disorder During Pregnancy | June 2004 | June 2004 |
| NCT00662428 | Completed | N/A | Increasing Cost-effectiveness of Inpatient Treatment of Affective Disorders | May 2008 | August 2011 |
| NCT00691535 | Completed | Genetics of Symptomatology and Treatment Response in Psychotic Major Depression | October 2003 | ||
| NCT00728208 | Completed | Phase 1 | GSK372475 PK Study in Healthy Volunteers | July 28, 2008 | December 29, 2008 |
| NCT00749359 | Completed | Phase 1 | PAXIL CR Bioequivalence Study | July 7, 2008 | September 16, 2008 |
| NCT00843011 | Completed | Phase 1 | Food and Relative Bioavailability Study | August 28, 2008 | October 23, 2008 |
| NCT00866294 | Completed | Phase 3 | Controlled-release Paroxetine in Major Depressive Disorder (Double-blind, Placebo-controlled Study) | April 2009 | February 2010 |
| NCT00886730 | Completed | Phase 1/Phase 2 | Primary Care Patients With Depression for Internet-Based Social Support | October 2008 | May 2011 |
| NCT00896363 | Completed | Phase 2 | Safety and Efficacy Study in Patients With Major Depressive Disorder | April 23, 2009 | February 9, 2010 |
| NCT00938184 | Completed | Phase 1 | Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects | July 14, 2009 | September 2, 2009 |
| NCT01000857 | Completed | Phase 1 | Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects | November 5, 2009 | February 25, 2010 |
| NCT01123642 | Completed | Project SERVE: Post Deployment Functioning | October 2010 | September 2014 | |
| NCT00001285 | Completed | Effects of Sex Hormones on Circadian Rhythm in Men and Women | August 1991 | June 2000 | |
| NCT00001415 | Completed | Glucocorticoid Effects on Cellular Cytokine Release | May 1994 | July 2000 | |
| NCT00001435 | Completed | Psychosocial Correlates and Coping Strategies Associated With Long-Term Survival of HIV-Infected Children | April 1995 | December 2000 | |
| NCT00001483 | Completed | Phase 2 | Acute Effectiveness of Additional Drugs to the Standard Treatment of Depression | June 1995 | May 2002 |
| NCT00001487 | Completed | Phase 2 | Treatment of Mid-Life-Related Mood Disorders | June 1995 | April 2004 |
| NCT00001659 | Completed | Consequences of Conjugal Bereavement in Adults | July 1997 | May 2002 | |
| NCT00001770 | Completed | Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety) | March 1998 | March 2003 | |
| NCT00018655 | Completed | Phase 2 | Integrated Intervention for Substance Abusers With Depressive Disorders | April 2000 | September 2012 |
| NCT00027001 | Completed | N/A | Qigong Therapy For Heart Device Patients | September 2000 | June 2003 |
| NCT00036309 | Completed | Phase 3 | Duloxetine Versus Placebo in the Prevention of Relapse of Major Depressive Disorder | May 2002 | July 2003 |
| NCT00044681 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Risperidone to Augment SSRI Therapy in Patients With Treatment-resistant Depression | October 2002 | March 2004 |
| NCT00044798 | Completed | Phase 3 | Magnetic Stimulation Therapy for Treating Vascular Depression | September 2001 | August 2008 |
| NCT00045773 | Completed | Treatment Outcome of Vascular Depression | April 2001 | April 2006 | |
| NCT00045916 | Completed | Phase 4 | Optimizing Electroconvulsive Therapy for Depression | February 2001 | December 2006 |
| NCT00057551 | Completed | Phase 4 | Research Evaluating the Value of Augmenting Medication With Psychotherapy | April 2003 | March 2007 |
| NCT01065597 | Completed | Phase 1 | Nonconvulsive Electrotherapy: a Proof-of-concept Trial | May 2010 | April 2014 |
| NCT01077596 | Completed | Carcinogenicity Study of Bupropion | June 2008 | March 2010 | |
| NCT01081197 | Completed | Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic | March 2010 | May 2013 | |
| NCT01093053 | Completed | N/A | Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations | September 2010 | September 2013 |
| NCT01096316 | Completed | N/A | Depression Attention for Women Now (The DAWN Study) | November 2009 | May 2015 |
| NCT01106313 | Completed | Insulin Resistance in Patients With Major Depression | July 2009 | January 2016 | |
| NCT01117753 | Completed | Phase 2 | Research on Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders | July 2009 | June 2014 |
| NCT00001232 | Completed | The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders | July 1988 | June 2000 | |
| NCT01153802 | Completed | Phase 1 | An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain DAT and SERT Occupancy,Pharmacokinetics and Safety of Single Oral Doses of GSK1360707, Using 11C- PE2I and 11C-DASB as PET Ligands | April 3, 2009 | October 12, 2009 |
| NCT01165255 | Completed | Bupropion and Specific Cardiovascular Malformations | June 2010 | December 2010 | |
| NCT01316926 | Completed | Phase 1 | Paxil CR Bioequivalence Study Brazil | September 9, 2009 | October 5, 2009 |
| NCT01339247 | Completed | Phase 1 | Paxil CR Bioequivalence Study Brazil - Fed Administration | October 20, 2009 | November 16, 2009 |
| NCT01360632 | Completed | Phase 3 | Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial) | June 2011 | September 2013 |
| NCT01360645 | Completed | Phase 3 | Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial) | July 2011 | June 2013 |
| NCT01360866 | Completed | Phase 3 | Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) | October 2011 | May 18, 2017 |
| NCT01399502 | Completed | Phase 1/Phase 2 | Promotion of Self-help Strategies for Depression | November 2011 | December 2012 |
| NCT01407575 | Completed | Phase 3 | Buprenorphine for Treatment Resistant Depression | September 2011 | August 2013 |
| NCT01424449 | Completed | Phase 1 | A PET Study in Healthy Volunteers | January 2010 | July 2010 |
| NCT01491035 | Completed | Phase 2 | Pharmacokinetics and Tolerability of Vortioxetine (Lu AA21004) in Child and Adolescent Patients With Depressive or Anxiety Disorder | April 2012 | June 2015 |
| NCT01528748 | Completed | Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence | April 2011 | July 2018 | |
| NCT01596608 | Completed | N/A | Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive Disorder | February 2012 | June 2019 |
| NCT01597661 | Completed | Bupropion & Cardio Birth Defect (Slone) | September 2011 | August 2012 | |
| NCT01643642 | Completed | N/A | Cost- Effectiveness Study of Brief Interventions for Mood and Anxiety Disorders | March 2010 | December 2012 |
| NCT01727726 | Completed | Phase 3 | A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial | December 2012 | November 10, 2016 |
| NCT01778907 | Completed | Phase 4 | Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE) | February 2013 | June 2017 |
| NCT01829100 | Completed | N/A | Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression | September 2009 | June 2012 |
| NCT01983033 | Completed | N/A | Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission | October 2013 | December 2016 |
| NCT02069912 | Completed | N/A | Multifaceted Depression and Cardiovascular Program | November 2006 | February 2009 |
| NCT02087579 | Completed | Phase 1 | Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants | February 2014 | December 2014 |
| NCT02151162 | Completed | N/A | Happy Nurse Project: Lifestyle Interventions to Maintain Healthy Mental State in Hospital Nurses | June 11, 2014 | September 6, 2016 |
| NCT02156128 | Completed | N/A | Subjective Memory Complaints, Objective Memory Performance and Cognitive Training | October 2013 | April 2015 |
| NCT02196506 | Completed | Phase 3 | Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress | July 2014 | May 2016 |
| NCT02224508 | Completed | Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks | September 2014 | January 2016 | |
| NCT02231268 | Completed | Observational Study to Assess a 6-months Treatment With Gladem | September 2000 | ||
| NCT02263872 | Completed | Phase 4 | Minocycline as an Adjunct for the Treatment of Depressive Symptoms: Pilot Randomized Controlled Trial | October 2014 | August 2016 |
| NCT02286024 | Completed | Study of Morphological and Perfusion Imaging Predictors of Pejorative Outcome in Major Depressive Disorder | November 3, 2014 | August 5, 2021 | |
| NCT02306551 | Completed | Well Being And Resilience: Mechanisms of Transmission of Health and Risk | September 2014 | September 2021 | |
| NCT02332239 | Completed | N/A | Text-Message-Based Depression Prevention for High-Risk Youth in the ED | February 2015 | May 2017 |
| NCT02346539 | Completed | Phase 1 | Effect of Nicotine on Brain Reward Pathways | February 2015 | November 2017 |
| NCT02405715 | Completed | Phase 2 | Therapy With an Oxytocin Adjunct for Major Depression | February 2015 | August 2016 |
| NCT02407704 | Completed | Phase 4 | A Multi-level Life-span Characterization of Adult-depression and Effects of Medication and Exercise | March 2015 | December 2016 |
| NCT02452892 | Completed | N/A | Low Field Magnetic Stimulation (LFMS) in Subjects With Treatment-Resistant Depression (TRD) | September 2015 | October 2016 |
| NCT02466477 | Completed | Phase 4 | Pharmacogenomic Decision Support With GeneSight Psychotropic to Guide the Treatment of Major Depressive Disorder | June 2015 | September 2019 |
| NCT02495142 | Completed | Psychosocial Issues and Bariatric Surgery | July 2010 | June 30, 2019 | |
| NCT02498392 | Completed | Phase 2 | An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress | October 7, 2015 | February 4, 2019 |
| NCT02499094 | Completed | N/A | Modeling and Predicting Real World Behavior Using Mobile Sensor Data on Patients With Major Depressive Disorder | December 2014 | |
| NCT02542891 | Completed | N/A | European Comparative Effectiveness Research on Internet-based Depression Treatment | September 2015 | September 15, 2018 |
| NCT02561156 | Completed | Phase 1 | TAK-653 Escalating Single and Multiple Dose Study in Healthy Participants | August 26, 2015 | September 23, 2017 |
| NCT02579642 | Completed | Phase 4 | Effects of Low-dose Ketamine as an Adjunct to Propofol-based Anesthesia for Electroconvulsive Therapy | October 2015 | May 2019 |
| NCT02664467 | Completed | N/A | Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project | May 2016 | November 2020 |
| NCT02675712 | Completed | Effect of African Drumming in Mood Disorders | April 2015 | August 2015 | |
| NCT02676882 | Completed | N/A | EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy | January 24, 2017 | November 30, 2018 |
| NCT02707887 | Completed | N/A | Technology Enhanced Behavioral Activation Treatment for Substance Use | January 2016 | December 2020 |
| NCT02741622 | Completed | N/A | Brain Derived Neurotropic Factor Response to Aerobic Exercise Intensity in Depressive Patients. | March 2016 | December 2016 |
| NCT02804867 | Completed | Spot Depression Study | March 2016 | September 2016 | |
| NCT02839837 | Completed | N/A | Acute Aerobic Exercise and Neuroplasticity in Depression | May 2016 | December 2018 |
| NCT02897843 | Completed | N/A | The Effect of Transcranial Direct Current Stimulation on Cognitive Side Effects of Electroconvulsive Therapy | February 16, 2017 | April 19, 2019 |
| NCT02939560 | Completed | N/A | TMS for Adults With Autism and Depression | September 2016 | September 20, 2018 |
| NCT02945735 | Completed | N/A | Gaze Contingent Feedback in Major Depressive Disorder (MDD) | November 6, 2016 | January 7, 2019 |
| NCT03040388 | Completed | Exploring Effects of Electroconvulsive Therapy on the Human Brain in Depression - The Danish ECT/MRI Study | August 9, 2017 | June 11, 2020 | |
| NCT03043560 | Completed | Phase 2 | Study to Treat Major Depressive Disorder With a New Medication | September 25, 2017 | August 30, 2019 |
| NCT03049813 | Completed | N/A | Virtual Reality Job Interview Training in Severe Mental Illness | June 1, 2017 | July 31, 2022 |
| NCT03193112 | Completed | Melatonin Decreases Eye Pressure in Normotensive Patients | June 16, 2017 | June 15, 2018 | |
| NCT03203395 | Completed | N/A | Screening for Depression and Anxiety in Patients With Heart Disease | January 1, 2017 | October 1, 2017 |
| NCT03219879 | Completed | N/A | Telephone-administered Relapse Prevention for Depression | September 29, 2017 | April 8, 2023 |
| NCT03226743 | Completed | N/A | Collaborative and Stepped Care in Mental Health (COMET) | July 12, 2018 | October 7, 2022 |
| NCT03228394 | Completed | Phase 2 | A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression | June 27, 2017 | May 10, 2020 |
| NCT03287986 | Completed | Brain Markers of Suicide Risk and Psychological Pain in Elderly Depressed Patients | August 18, 2017 | December 13, 2019 | |
| NCT03288714 | Completed | N/A | Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder | November 27, 2017 | June 1, 2019 |
| NCT03311529 | Completed | N/A | Effectiveness and Underlying Mechanisms of Applied Relaxation as Indicated Preventive Intervention | September 1, 2016 | December 30, 2019 |
| NCT03315793 | Completed | Phase 3 | A Study of Duloxetine (LY248686) in Japanese Children and Adolescents With Depressive Disorder | December 4, 2017 | November 8, 2019 |
| NCT03348865 | Completed | N/A | Fertility Life Counselling Aid- FeLiCiA | November 20, 2017 | June 30, 2018 |
| NCT03363750 | Completed | N/A | Study of Mind-Body Skills Groups for Adolescents With Depression in Primary Care | January 25, 2018 | September 4, 2019 |
| NCT03448809 | Completed | N/A | Randomized Feasibility Trial of Mind My Mind | December 8, 2015 | April 2, 2017 |
| NCT03460756 | Completed | Phase 2 | A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression | December 28, 2017 | July 5, 2019 |
| NCT03536442 | Completed | Promoting Attachment Through Healing | January 1, 2018 | December 1, 2018 | |
| NCT03572790 | Completed | N/A | Effects of Seven Day Prucalopride Administration in Healthy Volunteers | June 11, 2018 | May 17, 2019 |
| NCT03610373 | Completed | N/A | Testing Psychosocial Treatment Planning Methods for Youth Anxiety and Depression | October 4, 2016 | August 27, 2019 |
| NCT03646526 | Completed | Phase 1 | Bioavailability Study of Amitriptyline Hydrochloride Tablets | April 4, 2018 | January 31, 2019 |
| NCT03646539 | Completed | N/A | RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood | October 1, 2018 | July 4, 2019 |
| NCT03652220 | Completed | N/A | Meditation Based Lifestyle Modification in Depression | August 27, 2018 | July 20, 2020 |
| NCT03668457 | Completed | N/A | A Multi-component Intervention to Improve Medication Adherence in People With Depressive Disorders | March 1, 2020 | November 1, 2022 |
| NCT03692988 | Completed | N/A | Dignity Therapy for Patients With Early Dementia and Their Family | October 1, 2018 | May 31, 2021 |
| NCT03768830 | Completed | N/A | Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals | October 1, 2018 | February 5, 2019 |
| NCT03863366 | Completed | N/A | Effects of Acute Prucalopride Administration in Healthy Volunteers | February 7, 2017 | August 8, 2017 |
| NCT03897699 | Completed | N/A | Mindful Breathing and tDCS for Depression | March 1, 2019 | October 1, 2021 |
| NCT03907995 | Completed | N/A | Peer-led Group Intervention for Coping With Disaster | May 29, 2019 | December 31, 2019 |
| NCT03915821 | Completed | N/A | Memory Changes in Patients With Major Depression Disorder Treated With ECT | December 15, 2020 | March 30, 2022 |
| NCT03920475 | Completed | The Role of Inflammatory Processes in Development and Treatment of Depression | August 5, 2015 | March 6, 2018 | |
| NCT03925038 | Completed | N/A | Electronic Communication Augmented Mental Health Care | April 1, 2019 | February 19, 2024 |
| NCT03932825 | Completed | Phase 2 | Nitrous Oxide for Major Depressive Disorder | April 1, 2019 | March 31, 2021 |
| NCT03941301 | Completed | N/A | Light Therapy on Major Depression Disorder | June 1, 2019 | June 30, 2020 |
| NCT03971942 | Completed | N/A | Neutral and Positive Attention Bias Modification Training for Young Adults With Depressive Symptoms | December 24, 2017 | March 30, 2019 |
| NCT03981406 | Completed | N/A | Palliative Care and Quality of Life in Idiopathic Pulmonary Fibrosis | September 15, 2017 | March 1, 2019 |
| NCT03991650 | Completed | Monitoring Telemedicine Platform in Patients With Anxiety Symptoms and Alcohol Use Disorder | February 1, 2019 | November 5, 2019 | |
| NCT03995186 | Completed | N/A | Effects of Behavioural Activation on Emotional Cognition and Mood | February 20, 2019 | September 30, 2021 |
| NCT04008576 | Completed | N/A | Feasibility of a Group Blended Transdiagnostic CBT Protocol for Emotional Disorders | October 1, 2022 | June 30, 2023 |
| NCT04081519 | Completed | N/A | Stimulation of Parieto-hippocampal Connectivity in Patients With Major Depressive Disorder | August 2, 2016 | June 22, 2018 |
| NCT04091139 | Completed | Phase 2/Phase 3 | Research of Unified Protocol for the Treatment of Common Mental Disorders in Adolescents in Hong Kong | September 24, 2019 | May 22, 2020 |
| NCT04180683 | Completed | Comparison Study of the Different Abbreviated Versions of the Geriatric Depression Scale | March 1, 2020 | November 30, 2020 | |
| NCT04182061 | Completed | N/A | Internet Transdiagnostic-CBT for Anxiety and Depression in Adolescents | November 15, 2019 | September 30, 2023 |
| NCT04400162 | Completed | N/A | Augmentation of Depression Treatment by Gamified Network Retraining | May 14, 2020 | March 15, 2021 |
| NCT04433767 | Completed | Phase 2 | Depressed Mood Improvement Through Nicotine Dosing 2 | December 15, 2020 | October 7, 2022 |
| NCT04469322 | Completed | N/A | Pharmacogenetic Implementation Trial in Veterans With Treatment Refractory Depression | September 30, 2014 | June 26, 2018 |
| NCT04503343 | Completed | N/A | Effects of Non-drug Therapy on Cognitive Function in Healthy Individuals and Patients With First Episode Depression | July 30, 2020 | June 30, 2022 |
| NCT04584879 | Completed | N/A | Transdiagnostic Treatment Personalization | October 28, 2019 | September 15, 2020 |
| NCT04603235 | Completed | N/A | Manual-based Art Therapy for Adolescents With Depression | January 1, 2019 | October 8, 2020 |
| NCT04612777 | Completed | N/A | A Trial of "Opening Doors to Recovery" for Persons With Serious Mental Illnesses | June 15, 2014 | May 31, 2020 |
| NCT04616157 | Completed | N/A | Internet-based Cognitive Behavioral Therapy for Adolescents With Sleep Problems- a Feasibility Trial | September 1, 2018 | July 1, 2020 |
| NCT04635748 | Completed | Feasibility of Collateral Information Review and Its Impact on Clinical Decision-Making | December 3, 2019 | March 14, 2020 | |
| NCT04916275 | Completed | Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During the COVID-19 Pandemic | May 27, 2021 | August 31, 2021 | |
| NCT04965740 | Completed | Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids | June 4, 2021 | February 15, 2022 | |
| NCT04994470 | Completed | N/A | Web-based Self-help Intervention for Adolescents With Acute or Remitted Major Depressive Disorder | January 4, 2021 | May 2, 2022 |
| NCT05047627 | Completed | N/A | Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder | September 15, 2021 | March 1, 2023 |
| NCT05121831 | Completed | Phase 1 | A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of DGX-001 | February 24, 2022 | November 6, 2022 |
| NCT05223842 | Completed | N/A | Family Promoting Positive Emotions Pilot Study | December 1, 2021 | January 20, 2023 |
| NCT05264792 | Completed | N/A | Remote Coaching for Supporting the Implementation of Depression Care in Primary Care in Rural India | October 6, 2022 | December 31, 2023 |
| NCT05300204 | Completed | N/A | Evaluation of a Website to Improve Depression Literacy in Adolescents With Depression | January 4, 2021 | May 2, 2022 |
| NCT05300217 | Completed | N/A | Evaluation of a Website to Improve Depression Literacy in Adoldescents | January 4, 2021 | May 2, 2022 |
| NCT05326178 | Completed | N/A | Evaluation of a Website to Improve Depression Literacy in Parents of Healthy Adolescents | January 12, 2021 | May 2, 2022 |
| NCT05335564 | Completed | N/A | Evaluation of a Website to Improve Depression Literacy in Parents of Adolescents With Depression | January 20, 2021 | May 2, 2022 |
| NCT05384704 | Completed | N/A | A Single Group Study of Empower@Home-an Internet Cognitive Behavioral Therapy Intervention | May 23, 2022 | March 30, 2024 |
| NCT05418283 | Completed | N/A | Effects of 12-week Exercise Program on Sleep Quality and Fear of Death in Geriatric Individuals | June 10, 2022 | November 30, 2022 |
| NCT05446519 | Completed | Anxiety and / or Depressive Disorders in a Population of French Airline Pilot | September 1, 2022 | April 30, 2023 | |
| NCT05462652 | Completed | N/A | Self-guided Treatment for Adolescents Navigating Depression | July 28, 2022 | April 21, 2023 |
| NCT05482724 | Completed | N/A | Super Skills for Life Effectiveness in Clinical Settings | May 2, 2018 | December 14, 2022 |
| NCT05516238 | Completed | N/A | Systematic Use of Telepsychiatry for Outpatients | April 21, 2021 | April 26, 2022 |
| NCT05589090 | Completed | N/A | Super Skills for Life Effectiveness in the Online Modality | October 1, 2017 | December 1, 2022 |
| NCT05593276 | Completed | N/A | The Preliminary Effects of Empower@Home | January 5, 2023 | January 30, 2024 |
| NCT05601063 | Completed | Ascertaining Diagnosis Classification With Elicited Speech | October 1, 2020 | September 1, 2022 | |
| NCT05685758 | Completed | N/A | A Treatment for Depression Via a Gamified Mobile Phone Application Based on a New Cognitive Model | November 3, 2022 | July 31, 2023 |
| NCT05686408 | Completed | Phase 2 | Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD) | March 2, 2023 | September 29, 2023 |
| NCT05698420 | Completed | Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients | March 1, 2020 | October 31, 2020 | |
| NCT05732740 | Completed | N/A | Empower@Home:Connected - Feasibility and Preliminary Effect Study | January 17, 2023 | September 22, 2023 |
| NCT05959187 | Completed | N/A | A Single-center Randomized Controlled Study on the Effect of Pharmacogenomics Trial on Clinical Efficacy in Patients With Depression | July 15, 2020 | March 30, 2023 |
| NCT06094907 | Completed | Phase 2 | Safety, Tolerability and Antidepressant Effects of DMT in Patients With Depression | October 9, 2023 | March 30, 2024 |
| NCT06153004 | Completed | Phase 3 | OptimizeD Pilot Study | August 1, 2023 | March 31, 2024 |
| NCT06165445 | Completed | N/A | Optimizing tDCS Protocol for Clinical Use in Major Depressive Disorder | June 1, 2021 | March 1, 2023 |
| NCT06369805 | Completed | EVALUATION OF BLOOD BIOMARKER-BASED DIAGNOSTIC AID IN OUTPATIENTS SUFFERING FROM DEPRESSION | June 2, 2021 | November 17, 2022 | |
| NCT06280170 | Enrolling by invitation | N/A | AI to Support Mental Health Case Management Providers | February 19, 2024 | December 31, 2025 |
| NCT06440460 | Enrolling by invitation | Intergenerational Study of War-Affected Youth | May 27, 2024 | November 30, 2026 | |
| NCT05127837 | Enrolling by invitation | N/A | CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies | June 28, 2022 | February 12, 2024 |
| NCT05701345 | Enrolling by invitation | N/A | Study of Virtual Reality-based Medical Device for Patients With Depressive Disorder | March 9, 2023 | December 15, 2024 |
| NCT05251779 | Not yet recruiting | Early Phase 1 | A Clinical Study on the Effects of Inhalation of Volatile Oil of Cang-Ai Via the Nose on Patients With Depression | November 1, 2022 | December 1, 2022 |
| NCT06036160 | Not yet recruiting | N/A | Feasibility of Integrated Care of Depression in Primary Care Pathways | April 1, 2024 | November 1, 2026 |
| NCT06206226 | Not yet recruiting | N/A | The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study | August 2024 | August 2025 |
| NCT05927987 | Not yet recruiting | N/A | Feasibility and Acceptability of Problem Management Plus (PM+) for Prisoners in the Netherlands - a Pilot RCT | April 1, 2024 | December 31, 2024 |
| NCT06170801 | Not yet recruiting | N/A | Group Intervention for Interpersonal Skills | April 2024 | August 2026 |
| NCT06235411 | Not yet recruiting | N/A | Psilocybin in Alcohol Use Disorder With Comorbid Depression | January 2024 | July 2025 |
| NCT05547711 | Not yet recruiting | N/A | Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Recruited in an Outpatient Setting | October 15, 2022 | October 15, 2032 |
| NCT05423405 | Not yet recruiting | N/A | The Efficacy of Acupressure Therapy on Patient With Depression | August 1, 2022 | September 1, 2024 |
| NCT05867823 | Not yet recruiting | N/A | OcupApp: Occupational Self-analysis Intervention Through an Mobile Application | September 15, 2023 | July 1, 2024 |
| NCT05266560 | Not yet recruiting | Early Phase 1 | Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients | March 1, 2022 | December 31, 2024 |
| NCT06412315 | Not yet recruiting | N/A | 7T Amygdala and Citalopram Study | July 2024 | October 31, 2025 |
| NCT06072898 | Not yet recruiting | Phase 2 | A Randomized Neuroimaging Trial of Psilocybin in Depression | August 2024 | November 2027 |
| NCT06195436 | Not yet recruiting | N/A | Efficacy of Acceptance and Commitment Therapy on Serum GDF-15 Levels in Older Adults With and Without Depression: a Non-randomized Intervention Study | August 1, 2024 | January 1, 2026 |
| NCT06422559 | Not yet recruiting | N/A | Accelerated Intermittent Theta Burst Stimulation in Unipolar Versus Bipolar Depression | June 1, 2024 | January 1, 2025 |
| NCT05172375 | Not yet recruiting | N/A | Development of a Model for Shared Care in the Interface Between General Practice and Mental Health Care | January 1, 2023 | December 31, 2023 |
| NCT06105762 | Not yet recruiting | N/A | Ketogenic Diet for Depression | January 1, 2024 | July 1, 2027 |
| NCT05146427 | Not yet recruiting | N/A | Pilot Study: Investigating Mood Changes After Slow-wave Enhancement | January 1, 2025 | October 1, 2025 |
| NCT05730062 | Not yet recruiting | Phase 1 | Influence of Oxycodone on Individuals Taking an SSRI | March 15, 2023 | April 15, 2025 |
| NCT04977271 | Not yet recruiting | Phase 4 | Mood Disorders in Head and Neck Cancer Patients | July 28, 2024 | September 2028 |
| NCT06382532 | Not yet recruiting | Diagnosis of Depressive Disorder Malinger Using the Niacin Skin Response Test (NSRT) | May 1, 2024 | May 1, 2026 | |
| NCT05927129 | Recruiting | N/A | Research on the Biological Mechanism of the Efficacy of Psychotherapy for Depression Based on the fNIRS | January 1, 2022 | December 31, 2024 |
| NCT05989451 | Recruiting | N/A | Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders | September 1, 2023 | October 2026 |
| NCT04436757 | Recruiting | N/A | Self and Body-esteem in Socio-professional Rehabilitation | June 22, 2020 | June 2023 |
| NCT05641623 | Recruiting | Phase 2 | OSU6162 as add-on in SSRI/SNRI-resistant Depression | April 21, 2022 | August 31, 2026 |
| NCT06038409 | Recruiting | Ketamine Treatment Plans for Chronic Conditions | January 1, 2023 | June 1, 2024 | |
| NCT05637320 | Recruiting | N/A | Big Feelings: A Study on Children's Emotions in Therapy | October 1, 2022 | December 31, 2027 |
| NCT04572321 | Recruiting | Youth Depression and Suicide Research Network | August 26, 2020 | September 2032 | |
| NCT05631184 | Recruiting | N/A | Self-administered Acupressure for Depression | December 15, 2022 | December 31, 2025 |
| NCT06038721 | Recruiting | N/A | Unified Protocol: Community Connections | September 25, 2023 | September 25, 2028 |
| NCT06061653 | Recruiting | N/A | Augmentation of Interpersonal Psychotherapy With High-Definition Transcranial Direct Current Stimulation for Adolescent Depression | October 1, 2023 | December 31, 2025 |
| NCT03984084 | Recruiting | Biological Classification of Mental Disorders | June 9, 2015 | December 31, 2025 | |
| NCT06080646 | Recruiting | Reward Processing and Depressive Subtypes: Identifying Neural Biotypes | June 1, 2021 | September 1, 2025 | |
| NCT03314155 | Recruiting | N/A | Cerebral Neuroinflammation During Major Depressive Episode | December 7, 2018 | January 2024 |
| NCT06091163 | Recruiting | N/A | Ketogenic Diet for Treatment-Resistant Depression: Dietary Interventions for MEntal Health Study (DIME) | February 22, 2024 | March 2025 |
| NCT05932706 | Recruiting | N/A | Intervention Effect of High Definition Transcranial Alternating Current Stimulation (HD-tACS) on Depressive Disorder | September 1, 2022 | December 31, 2024 |
| NCT04666974 | Recruiting | N/A | Delivering iCBT to Address Mental Health Challenges in Correctional Officers and Other Public Safety Personnel | July 1, 2020 | December 30, 2024 |
| NCT06446856 | Recruiting | EVEN - Effects of VR on Empathy for Nature in Patients With Psychosis and Depressive Disorders | May 27, 2024 | August 1, 2024 | |
| NCT06369792 | Recruiting | PROSPECTIVE EVALUATION OF BLOOD BIOMARKERS AS AN AID TO DIAGNOSTIC AND TREATMENT IN DRUG-NAIVE PATIENTS WITH DEPRESSION | October 20, 2020 | December 31, 2024 | |
| NCT04747340 | Recruiting | N/A | Clinical Effectiveness of TARA Compared to Standard Treatment for Adolescents and Young Adults With Depression | March 12, 2021 | January 1, 2029 |
| NCT06361667 | Recruiting | N/A | Culture and Well-being: Art as Prescription Therapy ("Art on Prescription") | March 20, 2024 | January 15, 2025 |
| NCT05944926 | Recruiting | Phase 3 | Improving Outcomes in Depression in Primary Care in a Low Resource Setting | March 18, 2024 | December 30, 2026 |
| NCT05945342 | Recruiting | N/A | Development and Application of Comprehensive Intervention Techniques for Adolescent Depression | January 31, 2023 | June 30, 2025 |
| NCT04763330 | Recruiting | N/A | Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy | January 24, 2022 | March 31, 2026 |
| NCT05870501 | Recruiting | N/A | Synaptic Imaging and Network Activity in Treatment Resistant Depression | October 20, 2021 | September 11, 2023 |
| NCT05581277 | Recruiting | N/A | Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) in People With Post Covid-19 Condition. | January 15, 2023 | September 30, 2023 |
| NCT04857944 | Recruiting | N/A | Improving Depressive Symptoms Through Personalised Exercise and Activation | June 7, 2021 | September 30, 2024 |
| NCT05850442 | Recruiting | The Relationship Between Fibromyalgia Syndrome Parameters With Disease-Pain Severity and the Quality Of Life | April 1, 2023 | December 1, 2023 | |
| NCT06412562 | Recruiting | M3VAS Validation in Polish Population | May 9, 2024 | September 2026 | |
| NCT03222570 | Recruiting | Phase 2 | An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression | February 26, 2018 | December 2024 |
| NCT04990401 | Recruiting | N/A | Behavioral Activation Teletherapy to Increase Physical Activity | August 31, 2021 | December 2024 |
| NCT05551468 | Recruiting | N/A | StayFine: Personalised Relapse Prevention of Anxiety and Mood Disorders in Youths | December 16, 2019 | December 15, 2025 |
| NCT06109480 | Recruiting | N/A | Effect of HD-tDCS Assisted ECT for Depression Disorder | January 1, 2023 | December 31, 2025 |
| NCT06133309 | Recruiting | N/A | Phenomenological Explorations of the Esketamine-Induced Transient Dissociative State | March 19, 2024 | December 2024 |
| NCT05828056 | Recruiting | Prediction on the Recurrence of Manic and Depressive Episodes in Bipolar Disorder | March 2, 2020 | December 31, 2024 | |
| NCT05792540 | Recruiting | Phase 2 | Clinical Study to Evaluate the Possible Efficacy of Dapagliflozin and Atorvastatin in Patients With Major Depressive Disorders | June 6, 2023 | March 20, 2025 |
| NCT05548699 | Recruiting | Precision Mental Health in Diabetes - Subtypes of Mental Health, Trajectories, and Patterns With Glycaemic Control | May 2, 2023 | December 31, 2024 | |
| NCT05120232 | Recruiting | N/A | Flourishing and Virtue in Cognitive-Behavioral Therapy for Anxiety and Depressive Disorders | March 8, 2021 | July 1, 2023 |
| NCT05543083 | Recruiting | N/A | Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes | June 2, 2023 | April 30, 2027 |
| NCT05463562 | Recruiting | Multimodal Biomarkers of Electroconvulsive Therapy in Severe and Treatment-resistant Depression | February 24, 2022 | February 23, 2025 | |
| NCT06143293 | Recruiting | N/A | RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS | December 15, 2023 | December 15, 2025 |
| NCT05503966 | Recruiting | N/A | Combining Antidepressants and Attention Bias Modification in Depression | September 22, 2022 | December 30, 2024 |
| NCT05489835 | Recruiting | Work-Health-Life-Balance - Mental Resilience, Stability & Healthy Nutrition | January 11, 2023 | December 30, 2024 | |
| NCT05925322 | Recruiting | N/A | Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality | September 18, 2023 | September 30, 2028 |
| NCT05786066 | Recruiting | Phase 2 | The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects | April 3, 2023 | March 2033 |
| NCT06155201 | Recruiting | N/A | Development and Application of Intelligent Diagnosis and Treatment Norms for Children and Adolescents With Mental Disorders | November 1, 2022 | December 31, 2025 |
| NCT05280015 | Recruiting | Phase 2 | Microbiotherapy in Characterized Depressive Disorder | June 8, 2022 | December 2024 |
| NCT05400252 | Recruiting | N/A | Whole Health in VA Mental Health: Omnis Salutis | February 1, 2023 | October 31, 2026 |
| NCT05388461 | Recruiting | Acute Efficacy and 6 Months Follow up After Electroconvulsive Therapy | March 13, 2013 | December 2028 | |
| NCT02521012 | Recruiting | N/A | Follow-up Study With Clinical Vitamin D Supplementation Trial on Patients With Depression (DepFuD) | November 2015 | October 2025 |
| NCT06187454 | Recruiting | N/A | Transcranial Direct Current Stimulation for Depression | September 8, 2020 | December 31, 2026 |
| NCT06182722 | Recruiting | Association of Peripheral Immune Cells With Antidepressant Treatment Response | March 13, 2024 | December 2025 | |
| NCT06182787 | Recruiting | Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient | May 18, 2022 | January 19, 2024 | |
| NCT05768126 | Recruiting | Phase 4 | Prediction of ECT Treatment Response and Reduction of Cognitive Side-effects Using EEG and Rivastigmine | September 29, 2021 | January 2026 |
| NCT05371665 | Recruiting | N/A | Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children | March 28, 2022 | August 31, 2024 |
| NCT04160286 | Recruiting | The Danish Neuropsychological Study of the Adverse Effects of ECT | November 12, 2020 | December 2023 | |
| NCT05746546 | Recruiting | Phase 2 | Depressed Mood Improvement Through Nicotine Dosing-3 (Depressed MIND3) Extension | April 15, 2023 | October 31, 2026 |
| NCT05746273 | Recruiting | Phase 2 | Depressed Mood Improvement Through Nicotine Dosing 3 | April 15, 2023 | September 30, 2026 |
| NCT06408012 | Recruiting | An Innovative Master Platform for Clinical Trials in Mood Disorders | October 17, 2023 | March 31, 2026 | |
| NCT05962879 | Recruiting | N/A | Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness | March 22, 2024 | July 31, 2027 |
| NCT05963581 | Recruiting | N/A | Oxford Social Movement Activation Study | July 17, 2023 | July 16, 2024 |
| NCT03626103 | Recruiting | N/A | Intervention to Prevent Peer Violence & Depressive Symptoms Among At-Risk Adolescents | August 1, 2018 | February 2025 |
| NCT05708222 | Recruiting | Sleep Signal Analysis for Current Major Depressive Episode (SAMDE) | September 1, 2022 | June 2024 | |
| NCT06407154 | Recruiting | Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study, 2nd Wave | May 21, 2024 | September 30, 2024 | |
| NCT04282915 | Recruiting | N/A | Reducing Stigma Among Healthcare Providers (RESHAPE-cRCT) | February 22, 2022 | December 2024 |
| NCT04304911 | Recruiting | N/A | UP in Blended Format for Transdiagnostic Treatment of Emotional Disorders in the Spanish National Health System | March 1, 2023 | June 2025 |
| NCT06399406 | Recruiting | Phase 2 | Mindfulness Engaged Neurostimulation for Depression | May 15, 2024 | April 30, 2026 |
| NCT05976659 | Recruiting | N/A | Home-based Neuromodulation to Target Depression And Memory Symptoms in Older Adults | January 24, 2023 | June 30, 2025 |
| NCT03740139 | Suspended | N/A | The Police-Mental Health Linkage System | February 6, 2019 | May 31, 2026 |
| NCT01794559 | Suspended | N/A | Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression | March 1, 2013 | June 30, 2022 |
| NCT00356655 | Terminated | N/A | The ACHIEVA Study of Enhanced Pharmacist Care on Antidepressant Use and Response | July 2006 | May 2008 |
| NCT00867360 | Terminated | Phase 3 | Treatment of Psychotic Major Depression With Mifepristone | August 2005 | May 2009 |
| NCT05961163 | Terminated | Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study | July 24, 2023 | September 3, 2023 | |
| NCT00812812 | Terminated | Phase 4 | Paxil Japanese Post Marketing Paediatric Study in Depression (Double-blind, Placebo Controlled Study) | March 2009 | February 2011 |
| NCT00725270 | Terminated | Phase 2/Phase 3 | Treatment of Schizoaffective Disorder Using Mifepristone | April 1998 | May 2009 |
| NCT00700609 | Terminated | Phase 2 | Family Based Treatment of Depressed Adolescents | June 2008 | December 2009 |
| NCT01046214 | Terminated | Phase 1 | Bupropion Hydrochloride 300 mg Extended Release Tablets Under Fasting Conditions | January 2010 | |
| NCT04650217 | Terminated | Phase 4 | Levodopa and Exercise for Older Adults With Depression and Psychomotor Slowing | October 7, 2021 | December 31, 2021 |
| NCT01307475 | Terminated | Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions | February 2011 | April 1, 2017 | |
| NCT04760938 | Terminated | N/A | Treating Adolescents With CBT and OBH | February 1, 2021 | December 1, 2021 |
| NCT00655226 | Terminated | N/A | Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients | March 2008 | May 2010 |
| NCT00622947 | Terminated | N/A | The Antidepressant Effect of Right Temporal Low Frequency rTMS Compared to Sham | February 2008 | February 2010 |
| NCT05051449 | Terminated | Phase 1 | Ketamine for OUD and Comorbid Depression (OUDCD) | April 4, 2022 | November 30, 2023 |
| NCT00611052 | Terminated | N/A | Prevention of Adolescent Major Depression | March 2008 | December 2013 |
| NCT01809340 | Terminated | Phase 2 | The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression | June 2013 | July 2014 |
| NCT01830088 | Terminated | N/A | Family Based Treatment of Depressed Adolescents (AHUS) | October 2013 | June 2016 |
| NCT01928264 | Terminated | N/A | Physical Activity in Insurance Medicine: Effects on Patients With Psychiatric Disorders | August 2013 | April 2014 |
| NCT01928446 | Terminated | Phase 2/Phase 3 | Lithium for Suicidal Behavior in Mood Disorders | July 8, 2015 | August 13, 2019 |
| NCT05351866 | Terminated | N/A | Digital Therapeutic for Adolescent Depressive Symptoms in Hematology, Oncology, and Weight Management | January 26, 2023 | June 26, 2023 |
| NCT05461599 | Terminated | N/A | Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology | August 25, 2022 | May 16, 2023 |
| NCT02863380 | Terminated | N/A | Personalized rTMS for Resistant Depression | May 4, 2016 | January 21, 2021 |
| NCT02969876 | Terminated | Phase 4 | Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine | August 24, 2017 | August 6, 2018 |
| NCT03068676 | Terminated | N/A | Internet-delivered Treatments for Depression and Anxiety in Primary Care (SUMMA) | February 8, 2017 | February 9, 2018 |
| NCT00997490 | Terminated | Phase 3 | Study of the Antidepressant Efficacy of a Combination Herbal Drug Preparation (NEURAPAS Balance) | January 2001 | February 2003 |
| NCT03152409 | Terminated | Phase 2 | Salicylic Augmentation in Depression | November 15, 2018 | February 16, 2021 |
| NCT00488670 | Terminated | Phase 3 | Escitalopram and Depression in Elderly Alzheimer's Patients | December 2010 | June 2011 |
| NCT00896441 | Terminated | N/A | Functional MRI Before and After Treatment for Depression | February 2009 | June 2014 |
| NCT03291431 | Terminated | N/A | Intermittent Theta Burst for the Treatment of Alcohol Use Disorders in Veterans | December 1, 2017 | July 30, 2022 |
| NCT03395353 | Terminated | Phase 3 | A Study of Duloxetine (LY248686) in the Treatment of Japanese Children and Adolescents With Depressive Disorder | January 29, 2018 | July 4, 2020 |
| NCT03537547 | Terminated | Phase 4 | Combinatorial Pharmacogenomics Testing in Treatment-Naïve Major Depressive Disorder | May 4, 2018 | August 19, 2019 |
| NCT00880048 | Terminated | Phase 2 | A Randomised, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive Disorder | March 11, 2009 | June 21, 2010 |
| NCT00380042 | Terminated | Phase 1 | Assessment of the Safety and Effectiveness of Cortical Stimulation in Subjects With Major Depressive Disorder | September 2006 | March 2009 |
| NCT05189587 | Unknown status | N/A | Home-based Transcranial Electrical Stimulation (TES) in Patients With Chronic Tinnitus | March 1, 2022 | June 30, 2023 |
| NCT04161209 | Unknown status | N/A | Citalopram and Stress Reactivity | October 11, 2019 | September 2020 |
| NCT04202042 | Unknown status | N/A | Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers | October 21, 2019 | November 2020 |
| NCT05322642 | Unknown status | N/A | Efficacy of the Unified Protocol for the Transdiagnostic Treatment (UP-A; Ehrenreich-May et al., 2018) for Adolescents With Moderate Emotional Symptoms in Educational Settings | December 1, 2021 | January 30, 2024 |
| NCT05385614 | Unknown status | N/A | Efficacy of Gamified Cognitive Control Training Using de:)Press on Depression Severity add-on to Treatment as Usual | May 2022 | June 2023 |
| NCT05294614 | Unknown status | N/A | Implementation of a Psychological Online Intervention for Low to Moderate Depression in Primary Health Care | March 30, 2022 | July 2023 |
| NCT02562703 | Unknown status | Phase 1/Phase 2 | tVNS for Depression | November 2015 | July 2016 |
| NCT05286645 | Unknown status | N/A | Intervention Effect of High Definition Transcranial Direct Current Stimulation (HD-tDCS) on Depressive Disorder | January 1, 2021 | December 30, 2023 |
| NCT02605278 | Unknown status | N/A | Multicomponent Program for the Integrated Management of Chronic Pain and Depression in Primary Care | January 2015 | December 2017 |
| NCT02267980 | Unknown status | Phase 4 | Effect of the Addition of Ketamine to Sevoflurane Anesthesia in Electroconvulsive Therapy | July 2014 | October 2014 |
| NCT04169230 | Unknown status | N/A | Citalopram and Self Emotional Processing | October 11, 2019 | September 2020 |
| NCT00337012 | Unknown status | The Effect of Duloxetine on Interoceptive Awareness | July 2007 | ||
| NCT01903655 | Unknown status | N/A | Study of the Telomere-telomerase System and the Expression of Candidate Genes in the Leukocytes of Patients With Depressive Disorder: Search for Peripheral Markers of Somatic Stress | April 2010 | |
| NCT01831440 | Unknown status | N/A | Pharmacotherapy and Psychotherapy for MDD After Remission on Psychology and Neuroimaging | January 2011 | December 2014 |
| NCT04160377 | Unknown status | Phase 2 | A Clinical Trial of Fluvoxamine for Melancholia | August 1, 2019 | September 30, 2022 |
| NCT03001245 | Unknown status | N/A | Interpersonal Counseling (IPC) for Treatment of Depression in Adolescents | September 2016 | December 2018 |
| NCT03034343 | Unknown status | N/A | Effectiveness of a Brief Psychological Mindfulness Based Intervention for the Treatment of Depression in Primary Care | October 2016 | June 2020 |
| NCT01801319 | Unknown status | N/A | A Clinical Evaluation of Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression | June 2011 | December 2017 |
| NCT00521911 | Unknown status | Phase 2 | Detection and Treatment of Depression in Patients Admitted to the General Hospital | August 2007 | December 2008 |
| NCT01796132 | Unknown status | Phase 4 | Antidepressants During Pregnancy and Lactation: Pharmacokinetics and Clinical Implications | August 2012 | December 2018 |
| NCT03064477 | Unknown status | N/A | The Unified Protocol for the Treatment of Emotional Disorders in Spanish Public Mental Health System | September 14, 2014 | December 30, 2021 |
| NCT03944213 | Unknown status | Resting-state Functional Connectivity Throughout a Course of iTBS in Major Depression | July 23, 2018 | June 1, 2024 | |
| NCT04124276 | Unknown status | N/A | Evaluation of Efficacy of Lycium Barbarum Polysaccharide in Patients With Major Depressive Disorder | November 1, 2019 | June 1, 2021 |
| NCT04123301 | Unknown status | N/A | Theta-Burst Stimulation in Major Depressive Episodes With Mixed Characteristics. | March 8, 2019 | May 1, 2021 |
| NCT03188575 | Unknown status | N/A | Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPT | June 15, 2017 | August 30, 2019 |
| NCT03219008 | Unknown status | Phase 4 | Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological Characteristics | August 1, 2017 | December 2020 |
| NCT04067076 | Unknown status | Massive Mental Health Screening Using Smartphones in 24 Pre-graduate Education Centers in Mexico City: TEDUCA Survey Protocol | August 26, 2019 | August 2020 | |
| NCT01467804 | Unknown status | N/A | Randomized Double Blinding Controlled Study on" Jia Wei Xiao Yao Jiaonang" Treating Mild to Moderate Major Depressive Disorder | November 2011 | December 2012 |
| NCT04826510 | Unknown status | Phase 4 | Efficacy and Safety of Peropirone Hydrochloride Tablets in the Treatment of Adolescent Bipolar Disorder Depression | November 25, 2020 | June 30, 2021 |
| NCT04756544 | Unknown status | Phase 3 | The Influence of Probiotic Supplementation on Depressive Symptoms, Inflammation and Oxidative Stress Parameters and Faecal Microbiota in Patients With Depression Depending on Metabolic Syndrome Comorbidity | December 17, 2020 | December 31, 2023 |
| NCT03243799 | Unknown status | N/A | Effectiveness of a Psychoeducational Group Intervention in Patients With Depression and Physical Comorbidity | November 6, 2017 | December 2019 |
| NCT04067063 | Unknown status | Population Screening Using Smartphone in Milpa Alta | August 26, 2019 | April 2021 | |
| NCT04716777 | Unknown status | N/A | Brief Transdiagnostic Group CBT for Adolescents With Internalizing Problems: A Randomized Waitlist Controlled Trial | October 15, 2020 | September 20, 2023 |
| NCT03934723 | Unknown status | N/A | Does Antidepressant Use Blunt Adaptations to Exercise? | June 15, 2019 | July 2020 |
| NCT04685083 | Unknown status | Research on Voice Intelligent Monitoring Technology for Early Warning of Recurrence of Depression Disorder | December 31, 2020 | December 31, 2022 | |
| NCT04633707 | Unknown status | N/A | Adjunctive Bright Light Therapy for Patients With Depression | March 2021 | July 2022 |
| NCT04582058 | Unknown status | N/A | Mobile Health For Pacemaker Patientes | May 22, 2018 | November 20, 2022 |
| NCT03324906 | Unknown status | N/A | Effects of Transcranial Direct Current Stimulation (tDCS) on Individuals With Prader-Willi Syndrome | May 8, 2017 | November 2019 |
| NCT04560192 | Unknown status | N/A | Mindfulness Based Emotion Regulation Therapy in the Treatment of Depressive Rumination | July 1, 2020 | June 30, 2022 |
| NCT03354351 | Unknown status | Comorbid Mental Disease and Heart Disease in Men | December 1, 2017 | December 31, 2019 | |
| NCT04449627 | Unknown status | Psychological Impact of Admission With Covid-19 During the SARS-CoV-2 Pandemic: Naturalistic Cohort Study With a Digital Intervention | August 31, 2020 | January 31, 2021 | |
| NCT04066985 | Unknown status | N/A | Targeting Adolescent Depressive Symptoms Via Brief, Web-Based Interventions | October 1, 2019 | October 31, 2020 |
| NCT04441515 | Unknown status | N/A | Music After Stroke To Enhance Rehabilitation | April 30, 2021 | December 30, 2023 |
| NCT04376697 | Unknown status | N/A | Repetitive Transcranial Magnetic Stimulation Trajectory of Outcomes Study | March 18, 2019 | December 2021 |
| NCT03491696 | Unknown status | Phase 4 | Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression. | December 22, 2018 | September 2022 |
| NCT03509077 | Unknown status | Study of Addiction Criteria in the Elderly | June 19, 2018 | June 19, 2019 | |
| NCT04246905 | Unknown status | Phase 2 | A 12-weeks Study to Evaluate Sulforaphane in the Treatment of Depression | July 15, 2020 | December 31, 2021 |
| NCT04034576 | Unknown status | N/A | Mindfulness and Relaxation Interventions in Individual Psychotherapies for Children and Adolescents | April 30, 2019 | February 2024 |
| NCT04242862 | Unknown status | Burn Out Among Medical Family Doctors | November 1, 2016 | June 1, 2022 | |
| NCT03607331 | Unknown status | Early Phase 1 | Auricular Concha Electro-acupuncture for the Treatment of Depression | September 17, 2018 | August 1, 2019 |
| NCT04234776 | Unknown status | Phase 4 | Intramuscular Ketamine Versus Aripiprazole and Escitalopram in the Treatment of Resistant Depression | April 3, 2018 | April 3, 2021 |
| NCT03623555 | Unknown status | Applied Social Neuroscience: the Building Resilience Among Women Project | March 1, 2019 | September 2020 | |
| NCT01916200 | Withdrawn | Phase 4 | Efficacy and Safety of Paroxetine Controlled Release for Major Depressive Disorder in Irritable Bowel Syndrome Patients | January 2014 | September 2014 |
| NCT02128568 | Withdrawn | N/A | Sub-Trial of the Youth Readiness Intervention (YRI): Treatment of Control Group and Addition of Stress Biomarkers | March 2014 | September 2017 |
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| NCT02238730 | Withdrawn | N/A | Ultrabrief Right Unilateral and Brief Pulse Bitemporal Electroconvulsive Therapy | September 2014 | February 15, 2017 |
| NCT04220125 | Withdrawn | Phase 4 | Preoperative Ketamine and Perioperative Depression | September 1, 2022 | February 2, 2023 |
| NCT01748708 | Withdrawn | N/A | Evaluating the Efficacy of Magnetic Seizure Therapy in Treatment Resistant Depression. | December 2016 | December 2016 |
| NCT01568684 | Withdrawn | Phase 1 | Brain Imaging, Genetics and Treatment for Major Depression | March 12, 2012 | December 11, 2012 |
| NCT00525928 | Withdrawn | N/A | Mood and Anti-craving Effects of Varenicline in Psychiatric Inpatients | October 2007 | October 2008 |
| NCT05594667 | Withdrawn | Phase 2 | Effect of SSRIs on Response to Psilocybin Therapy | January 1, 2023 | March 14, 2023 |
| NCT02410421 | Withdrawn | Phase 2 | e-PAT Neuromod Evaluation of Personalized rTMS for Resistant Depression | May 2020 |
- Disase is a (Disease Ontology)
- DOID:3324
- Cross Reference ID (Disease Ontology)
- ICD10CM:F33.9
- Cross Reference ID (Disease Ontology)
- MESH:D003863
- Cross Reference ID (Disease Ontology)
- NCI:C2982
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:41006004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0011570
- Exact Synonym (Disease Ontology)
- mental depression
- Disase Synonym (Disease Ontology)
- depression