thymoma (Cancer)
Information
- Disease name
- thymoma
- Disease ID
- DOID:3275
- Description
- "A thymus cancer that derives_from epithelial cells located_in the thymus. The tumor cells in a thymoma look similar to the normal cells of the thymus, grow slowly, and rarely spread beyond the thymus." [url:http\://cancergenome.nih.gov/cancersselected/Thymoma, url:http\://en.wikipedia.org/wiki/Thymoma, url:http\://www.cancer.gov/cancertopics/pdq/treatment/thymoma/patient/page1]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05682742 | Active, not recruiting | N/A | Clinical Investigation of the da Vinci Surgical System | December 12, 2022 | August 31, 2028 |
| NCT05150210 | Active, not recruiting | N/A | SP Thoracic IDE Study | July 20, 2022 | July 2028 |
| NCT04375267 | Active, not recruiting | Phase 1 | 177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours | April 23, 2020 | June 30, 2024 |
| NCT01025089 | Active, not recruiting | Phase 2 | Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma | December 2009 | December 2024 |
| NCT05455840 | Active, not recruiting | N/A | A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Anterior Mediastinal Disease | August 3, 2022 | April 11, 2024 |
| NCT03968315 | Active, not recruiting | N/A | An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent Thymoma | June 8, 2011 | April 30, 2025 |
| NCT01621568 | Active, not recruiting | Phase 2 | Sunitinib for Advanced Thymus Cancer Following Earlier Treatment | May 15, 2012 | July 31, 2024 |
| NCT03921671 | Active, not recruiting | Phase 2 | Ramucirumab and Carbo-Paclitaxel for Untreated Thymic Carcinoma / B3 Thymoma With Carcinoma (RELEVENT) | November 1, 2018 | July 16, 2024 |
| NCT00965627 | Completed | Biology of Thymic Tumors | June 2008 | August 2009 | |
| NCT01102192 | Completed | The Role of the Thymus in Myasthenia Gravis | August 2007 | December 2012 | |
| NCT01272817 | Completed | N/A | Nonmyeloablative Allogeneic Transplant | October 2001 | October 2015 |
| NCT01364727 | Completed | Phase 2 | A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic Malignancies | June 2011 | December 31, 2018 |
| NCT00010257 | Completed | Phase 2 | Carboplatin Combined With Paclitaxel in Treating Patients With Advanced Thymoma | June 19, 2001 | August 2012 |
| NCT00198133 | Completed | Phase 2 | Phase II Study of Alimta (Pemetrexed) Treatment of Advanced Thymoma and Thymic Carcinoma | January 2005 | May 2012 |
| NCT00332969 | Completed | Phase 2 | Efficacy of Octreotide Treatment in Patients With Primary Inoperable Thymoma | September 2005 | |
| NCT00369889 | Completed | Phase 2 | A Study to Test the Safety and Efficacy of Erlotinib Plus Bevacizumab to Treat Advanced Thymoma and Thymic Cancer | August 2006 | September 2007 |
| NCT00387868 | Completed | Phase 2 | Preoperative Treatment of Patients With High Risk Thymoma | October 2006 | November 2014 |
| NCT00589290 | Completed | Phase 2 | Belinostat (PXD101) to Treat Tumors of the Thymus at an Advanced Stage | December 2007 | June 2014 |
| NCT00921739 | Completed | Phase 1 | Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies | September 11, 2009 | November 2016 |
| NCT00965250 | Completed | Phase 2 | Multicenter Phase II Study of IMC-A12 in Patients With Thymoma and Thymic Carcinoma Who Have Been Previously Treated With Chemotherapy | August 2009 | June 2016 |
| NCT02220855 | Completed | Phase 2 | A Study of BKM120 (Buparlisib) in Relapsed or Refractory Thymomas | October 1, 2014 | March 9, 2021 |
| NCT03023319 | Completed | Phase 1 | Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors | December 10, 2019 | May 10, 2022 |
| NCT03078699 | Completed | N/A | Prospective Study of Stereotactic Body Radiation Therapy for Thymoma Inoma: Therapeutic Effect and Toxicity Assessment | January 1, 2005 | September 1, 2016 |
| NCT03288662 | Completed | N/A | Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors | October 1, 2013 | July 31, 2017 |
| NCT03517488 | Completed | Phase 1 | A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors | July 10, 2018 | September 6, 2022 |
| NCT04577495 | Completed | Prognostic Factors in Patients Submitted to Surgical Treatment for Thymoma | January 2005 | March 31, 2020 | |
| NCT05001113 | Completed | N/A | Surgery for Masaoka-Koga I-II Thymoma | August 15, 2021 | August 17, 2022 |
| NCT01385722 | Enrolling by invitation | Molecular Analysis of Thoracic Malignancies | August 2011 | June 2031 | |
| NCT06029621 | Recruiting | N/A | Robot-assisted vs VATS for Thymoma | November 20, 2023 | September 19, 2030 |
| NCT03076554 | Recruiting | Phase 2 | A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy | April 19, 2017 | June 30, 2025 |
| NCT06086327 | Recruiting | Early Phase 1 | Application of 68Ga-Pentixafor PET/CT for Thymoma | June 22, 2023 | December 31, 2024 |
| NCT01950572 | Recruiting | Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma | September 9, 2013 | ||
| NCT04072393 | Recruiting | N/A | Cardiac Rehabilitation for Patients Receiving Radiation Therapy for Thoracic Cancers | January 15, 2021 | March 31, 2025 |
| NCT04162691 | Recruiting | Single Cell Sequencing Analysis of Thymoma | June 6, 2020 | December 31, 2023 | |
| NCT06248515 | Recruiting | Phase 2 | A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors | April 25, 2024 | December 2026 |
| NCT06301945 | Recruiting | Artificial Intelligence Prediction Tool in Thymic Epithelial Tumors | August 1, 2023 | August 1, 2027 | |
| NCT05214612 | Recruiting | Predictors and Prognostic Factors of Myasthenia Gravis Outcome | January 1, 2022 | August 31, 2024 | |
| NCT05255965 | Recruiting | IL-8+ naïve T Cells as a Biomarker for Thymoma Identification | September 1, 2022 | December 31, 2025 | |
| NCT05262582 | Recruiting | N/A | Comparison of Single Port and Two Ports Robotic Assisted Thoracic Surgery for Thymectomy | May 10, 2022 | January 1, 2025 |
| NCT02633553 | Recruiting | N/A | Adjuvant Radiotherapy for Stage II/III Thymoma After Complete Resection | January 10, 2018 | December 2029 |
| NCT06010277 | Recruiting | Phase 4 | Folinic Acid for Prevention of Pemetrexed-induced Toxicity | February 6, 2023 | January 2024 |
| NCT02062632 | Terminated | Phase 2 | Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy | April 14, 2014 | November 6, 2017 |
| NCT01100944 | Terminated | Phase 1/Phase 2 | A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, Malignancies | March 4, 2010 | October 21, 2015 |
| NCT00818090 | Terminated | Phase 2 | Paclitaxel and Cisplatin for Thymic Neoplasm | September 2008 | November 2011 |
| NCT03193437 | Terminated | Phase 2 | Selinexor in Patients With Advanced Thymic Epithelial Tumor Progressing After Primary Chemotherapy | April 3, 2018 | January 31, 2022 |
| NCT01258868 | Terminated | Phase 1 | Tumor Cell Vaccines With ISCOMATRIX Adjuvant and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers and Malignant Pleural Mesotheliomas | December 1, 2010 | June 13, 2016 |
| NCT03290183 | Unknown status | Confocal Laser Endomicroscopy in Pleural Malignancies | August 28, 2017 | March 1, 2019 | |
| NCT02014805 | Unknown status | Phase 3 | Postoperative Conformal Radiotherapy for Stage II-III B Type Thymoma | July 2013 | July 2022 |
| NCT03613272 | Unknown status | N/A | The Curative Effect of Extended Thymectomy Performed Through Subxiphoid-right VATS Approach With Elevation of Sternum | July 1, 2018 | December 1, 2023 |
| NCT01242072 | Unknown status | Phase 1 | Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies | November 2010 | December 2012 |
| NCT03466827 | Unknown status | Phase 2 | Selinexor in Patients With Advanced Thymoma and Thymic Carcinoma | October 12, 2017 | July 1, 2020 |
| NCT05407649 | Unknown status | Phase 2 | Abscopal Effect of Radiotherapy in Combination With rhGM-CSF for Advanced Thymic Epithelial Tumours | January 1, 2016 | December 30, 2023 |
| NCT02948855 | Withdrawn | Regulation of LncRNA For Breg in Patients With Thymoma and Autoimmune Diseases | October 2016 | May 2018 |
- Disase is a (Disease Ontology)
- DOID:3277
- Cross Reference ID (Disease Ontology)
- ICDO:8580/3
- Cross Reference ID (Disease Ontology)
- MESH:D013945
- Cross Reference ID (Disease Ontology)
- NCI:C3411
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:444231005
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0040100
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0100522
- OrphaNumber from OrphaNet (Orphanet)
- 99867
- MeSH unique ID (MeSH (Medical Subject Headings))
- D013945