chronic fatigue syndrome
Information
- Disease name
- chronic fatigue syndrome
- Disease ID
- DOID:8544
- Description
- "A syndrome that involves prolonged and severe tiredness or weariness that is unrelated to exertion, is not relieved by rest and for a minimum of six months and is not directly caused by other conditions." [url:http\://en.wikipedia.org/wiki/Chronic_fatigue_syndrome]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05167227 | Active, not recruiting | N/A | Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center? | November 30, 2021 | October 31, 2024 |
| NCT03075254 | Active, not recruiting | Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord | March 15, 2017 | December 13, 2024 | |
| NCT05323838 | Active, not recruiting | Influence of Co-diagnosis of Chronic Fatigue Syndrome in Patients With Fibromyalgia. | June 9, 2021 | November 16, 2024 | |
| NCT05664711 | Active, not recruiting | Phase 1 | Effect of Stellate Ganglion Block on ME/CFS | March 15, 2023 | May 2024 |
| NCT04622293 | Active, not recruiting | Phase 4 | A Trial of Solriamfetol in the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | April 27, 2021 | May 1, 2024 |
| NCT04532827 | Active, not recruiting | N/A | Web-based Rehabilitation for Persistent Physical Symptoms. | August 18, 2020 | September 30, 2023 |
| NCT02374112 | Active, not recruiting | N/A | Creatine Supplementation in Chronic Fatigue Syndrome | January 2016 | December 2023 |
| NCT05130099 | Active, not recruiting | N/A | A Complex Intervention for Chronically Fatigued Lymphoma Survivors | November 20, 2021 | June 30, 2025 |
| NCT00215813 | Available | Ampligen in Chronic Fatigue Syndrome | |||
| NCT00598585 | Completed | Phase 4 | Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS | July 2002 | December 2010 |
| NCT00810329 | Completed | Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome | July 2007 | April 2011 | |
| NCT00848692 | Completed | Phase 2/Phase 3 | Drug Intervention in Chronic Fatigue Syndrome | June 2008 | June 2010 |
| NCT00860236 | Completed | Phase 4 | Giardia Induced Fatigue and Functional Gastrointestinal Diseases | March 2009 | June 2010 |
| NCT00893438 | Completed | N/A | Efficacy of Web-based Cognitive Behavioural Treatment for Adolescents With Chronic Fatigue Syndrome | January 2008 | November 2011 |
| NCT00920777 | Completed | N/A | Survey and Cognitive Behavior Therapy for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis | May 2009 | May 2015 |
| NCT00997451 | Completed | N/A | Fatigue Self-Management in Primary Care | February 2009 | December 2011 |
| NCT01040429 | Completed | Phase 2 | The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial | February 2010 | November 2012 |
| NCT01046370 | Completed | N/A | A Pilot Study of Amygdala Retraining Program in Patients With Chronic Fatigue Syndrome, Chronic Fatigue and Fibromyalgia | October 2009 | May 2011 |
| NCT01071044 | Completed | Phase 4 | Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome | November 2009 | March 2011 |
| NCT01106339 | Completed | Immune Patterns in Pain Patients DSM-IV | August 2007 | April 2013 | |
| NCT01108549 | Completed | N/A | Treatment of Chronic Fatigue Syndrome and Fibromyalgia With D-ribose- a Multicenter Study | April 2009 | September 2009 |
| NCT01156909 | Completed | Phase 2 | B-cell Depletion Using the Monoclonal Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome | October 2010 | February 2014 |
| NCT01507701 | Completed | N/A | Pilot Study for the NorCAPITAL Trial | January 2010 | |
| NCT01512342 | Completed | Phase 2 | Pacing Activity Self-management for Patients With Chronic Fatigue Syndrome | August 2011 | August 2014 |
| NCT01534130 | Completed | N/A | Acupuncture for the Sleep Disorder of Chronic Fatigue Syndrome | April 2011 | August 2012 |
| NCT01650636 | Completed | N/A | Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process | October 2010 | May 2017 |
| NCT01651754 | Completed | N/A | Humoral and Cellular Immune Responses After Influenza Vaccination in Patients With Postcancer Fatigue and in Patients With Chronic Fatigue Syndrome | September 2010 | June 2012 |
| NCT01686074 | Completed | Motor Control in Chronic Fatigue Syndrome and Fibromyalgia | September 2012 | December 2014 | |
| NCT01689467 | Completed | N/A | Efficacy and Safety of Fermented Velvet Antler Extract on Fatigue Recovery After Exercise | April 25, 2013 | June 26, 2014 |
| NCT01742013 | Completed | Phase 3 | Investigator Initiated Clinical Study to Explore the Efficacy and Safety of Human Placenta Hydrolysate in the Chronic Fatigue Patients | January 2013 | September 2013 |
| NCT01765725 | Completed | N/A | Coping With Chronic Fatigue Syndrome: Development of a Community-based Patient Education Program | April 2011 | December 2016 |
| NCT06463106 | Completed | Endothelial Dysfunction in Post-infection Fatigue Syndromes | June 1, 2021 | December 1, 2022 | |
| NCT00100412 | Completed | N/A | Hyporeactivity and Gulf War Illness | October 1999 | September 2002 |
| NCT00215800 | Completed | Phase 3 | The Study of the Safety and Efficacy of Ampligen in Chronic Fatigue Syndrome | December 1998 | February 2004 |
| NCT00252629 | Completed | N/A | Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment | November 2005 | November 2010 |
| NCT00433355 | Completed | Epstein-Barr Virus as a Possible Cause for Chronic Fatigue Syndrome | January 2007 | October 2008 | |
| NCT00468013 | Completed | N/A | A Computer-Based Intervention for Medically Unexplained Physical Symptoms | March 2007 | March 2010 |
| NCT00478465 | Completed | Phase 1/Phase 2 | Valganciclovir (Valcyte) for Chronic Fatigue Syndrome Patients Who Have Elevated Antibody Titers Against Human Herpes Virus 6 (HHV-6)and Epstein-Barr Virus (EBV) | May 2007 | August 2007 |
| NCT00540254 | Completed | Phase 1/Phase 2 | Behavioral Insomnia Therapy With Chronic Fatigue Syndrome | September 2007 | July 2010 |
| NCT00580619 | Completed | Phase 1 | Autonomic Nervous System and Chronic Fatigue Syndrome | April 2007 | January 2017 |
| NCT01806246 | Completed | N/A | A Rehabilitation Program for Adolescents With Chronic Fatigue Syndrome | February 2013 | September 2015 |
| NCT01873482 | Completed | N/A | Traditional African Healing Ceremony in a U.S. Population | May 2014 | |
| NCT02055898 | Completed | Phase 4 | SWS And Daytime Functioning in Chronic FatiguE Syndrome (SAFFE) | April 2014 | August 2015 |
| NCT02063126 | Completed | Phase 2/Phase 3 | Clinical Trial to Measure the Maximun HR After ReConnect ® Supplementation vs. Placebo in CFS. | January 2013 | December 2013 |
| NCT02075489 | Completed | N/A | Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans | September 2012 | October 2017 |
| NCT02082730 | Completed | N/A | The Feasibility, Acceptability and Clinical Utility of a New Remote-mobile Technology Intervention (ASARM) for CFS/ME in a Paediatric Population | January 2013 | August 1, 2014 |
| NCT02094820 | Completed | Psychological Wellbeing in Chronic Fatigue Syndrome | May 2014 | January 2015 | |
| NCT02108210 | Completed | Phase 2/Phase 3 | Cytokine Inhibition in Chronic Fatigue Syndrome Patients | June 2014 | May 2016 |
| NCT02213679 | Completed | N/A | Guanidinoacetic Acid Loading for Chronic Fatigue Syndrome | August 2014 | July 2015 |
| NCT02669212 | Completed | N/A | Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health | October 10, 2016 | January 11, 2022 |
| NCT02807649 | Completed | N/A | Effect of Ginko and Cistanche Against Fatigue Symptoms | May 2015 | December 2015 |
| NCT02970240 | Completed | Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy | June 2014 | November 2020 | |
| NCT03029377 | Completed | N/A | Noradrenergic and Stress-Related Etiologies of Chronic Fatigue Syndrome | January 2017 | February 23, 2018 |
| NCT03186027 | Completed | N/A | Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis | June 28, 2017 | September 1, 2021 |
| NCT03497585 | Completed | Developing an Activity Pacing Framework: Feasibility and Acceptability | May 21, 2018 | December 31, 2019 | |
| NCT03562325 | Completed | N/A | ACT for ME/CFS - an Open Case Trial | November 10, 2012 | October 31, 2017 |
| NCT03567811 | Completed | N/A | Exertional Exhaustion in Chronic Fatigue Syndrome | August 1, 2013 | July 31, 2018 |
| NCT03613129 | Completed | Phase 1/Phase 2 | Clinical Trial to Investigate CT38 in the Treatment of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome | July 23, 2018 | April 30, 2019 |
| NCT03674541 | Completed | Phase 2 | The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome | January 14, 2020 | December 20, 2021 |
| NCT03691987 | Completed | Phase 2 | The Comeback Study | February 15, 2019 | December 31, 2023 |
| NCT03844412 | Completed | Phase 2 | Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments | November 4, 2019 | May 30, 2024 |
| NCT04026425 | Completed | N/A | Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS | August 1, 2018 | March 31, 2023 |
| NCT04301609 | Completed | N/A | Clinical Trial to Assess the Improvement of Fatigue, Sleep Problems, Anxiety / Depression, Neurovegetatives Alterations and Quality of Life After the Administration of ImmunoVita® in Chronic Fatigue Syndrome Patients | November 10, 2021 | January 31, 2023 |
| NCT04381780 | Completed | N/A | Treatment of Fibromyalgia With Recovery Factors | May 6, 2020 | January 15, 2021 |
| NCT04381793 | Completed | N/A | Treatment of CFS & Fibromyalgia With Recovery Factors | May 20, 2019 | July 4, 2020 |
| NCT04399330 | Completed | ME/CFS, Hypermobility and Craniocervical Obstructions | June 1, 2019 | September 30, 2019 | |
| NCT04741841 | Completed | N/A | Effect of Probiotics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | March 30, 2020 | June 30, 2021 |
| NCT04859257 | Completed | Exploring the Biological Basis of Chronic Fatigue Syndrome | May 26, 2021 | December 1, 2021 | |
| NCT05013606 | Completed | N/A | Hydrogen Water Treatment for Chronic Fatigue Syndrome | April 1, 2019 | June 1, 2021 |
| NCT05608629 | Completed | N/A | Vagus Nerve Stimulation as Treatment for Long Covid | June 6, 2022 | December 5, 2022 |
| NCT05611606 | Completed | Welfare Benefits in Functional Somatic Disorders | November 10, 2011 | August 30, 2015 | |
| NCT05631860 | Completed | Psychological Risk Factors for Functional Somatic Disorders | November 10, 2011 | August 30, 2022 | |
| NCT05730660 | Completed | N/A | Quercetin Phytosome® Chronic Fatigue Syndrome | September 1, 2022 | January 31, 2023 |
| NCT05811663 | Completed | Health Care Use and Costs of Functional Somatic Disorders | November 10, 2011 | August 30, 2015 | |
| NCT05973136 | Completed | N/A | Telerehabilitation for Post COVID-19 Condition | April 1, 2022 | August 8, 2022 |
| NCT06006715 | Completed | Psychiatric Disorders and Functional Somatic Disorders | November 10, 2011 | August 30, 2022 | |
| NCT00032461 | Completed | Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans | November 1998 | April 2001 | |
| NCT06145867 | Enrolling by invitation | N/A | A Feasibility Study: Assessing Photobiomodulation in Myalgic Encephalomyelitis | April 24, 2024 | August 1, 2024 |
| NCT03409653 | Enrolling by invitation | Complex Chronic Diseases Program Data Registry | June 12, 2017 | September 30, 2025 | |
| NCT06235177 | Not yet recruiting | Early Phase 1 | Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues | July 24, 2024 | September 19, 2025 |
| NCT06170645 | Not yet recruiting | N/A | Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue | June 2024 | August 2025 |
| NCT04403854 | Not yet recruiting | Structural Problems in Brainstem and Cervical Spine Cord in ME/CFS | April 1, 2021 | March 31, 2026 | |
| NCT06245642 | Not yet recruiting | Phase 4 | Compound Xiwujia Granules Treat Chronic Fatigue Syndrome | March 1, 2024 | November 1, 2025 |
| NCT06011135 | Not yet recruiting | Exploring Worry in CFS/ME | October 1, 2023 | May 31, 2024 | |
| NCT05967494 | Not yet recruiting | Discovering Trends in Chronic Fatigue Syndrome Patients' Clinical Study Experiences | August 2024 | August 2026 | |
| NCT04955587 | Recruiting | A Longitudinal Study on Longstanding Complicated Fatigue | August 24, 2021 | August 2025 | |
| NCT04542161 | Recruiting | Phase 2 | Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | September 1, 2020 | April 30, 2025 |
| NCT05454683 | Recruiting | N/A | Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | September 5, 2022 | December 31, 2024 |
| NCT04363606 | Recruiting | N/A | Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability | May 27, 2020 | December 2024 |
| NCT04740736 | Recruiting | N/A | Cardiovascular Analysis of PEM | August 31, 2021 | February 28, 2025 |
| NCT05967052 | Recruiting | Phase 2 | Investigation of Treating Chronic Fatigue Syndrome After COVID With Pharmacotherapy (Pregabalin) or Complex Rehabilitation | October 24, 2023 | March 1, 2028 |
| NCT05741112 | Recruiting | N/A | The Long COVID-19 Wearable Device Study | November 16, 2023 | December 1, 2025 |
| NCT05525598 | Recruiting | N/A | Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders | August 24, 2022 | June 1, 2026 |
| NCT05236465 | Recruiting | N/A | A 3-day Course for CFS/ME | March 21, 2022 | April 1, 2026 |
| NCT03807973 | Recruiting | Phase 1 | Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes. | October 5, 2021 | October 5, 2025 |
| NCT03759522 | Recruiting | Phase 1 | Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714. | February 3, 2019 | April 10, 2025 |
| NCT05587777 | Recruiting | Monitoring of Chronic Conditions in Breast Cancer | June 15, 2022 | June 15, 2028 | |
| NCT06128967 | Recruiting | Phase 3 | A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial | October 18, 2023 | May 18, 2025 |
| NCT05719493 | Recruiting | N/A | Effectiveness and Health Benefits of a Nutritional, Chronobiological and Physical Exercise Intervention in Fibromyalgia and Chronic Fatigue Syndrome (SYNCHRONIZE +) | October 4, 2021 | March 2024 |
| NCT02018497 | Recruiting | Essential Hypotension and Allostasis Registry | January 1995 | June 30, 2024 | |
| NCT00498485 | Terminated | Phase 4 | Use of Xyrem to Improve Sleep in Chronic Fatigue Syndrome | May 2007 | December 2008 |
| NCT02174003 | Terminated | Whole Body Hyperthermia Registry Study | June 2014 | ||
| NCT01156922 | Terminated | Phase 2 | B-cell Depletion Using the Monoclonal Anti-CD20 Antibody Rituximab in Very Severe Chronic Fatigue Syndrome | June 2010 | April 2016 |
| NCT00983502 | Terminated | Pilot Study of Alternative Treatments of Unexplained Chronic Fatigue | August 2008 | October 2010 | |
| NCT00977171 | Terminated | Phase 2 | Study To Assess The Clinical Benefit Of Droxidopa In Subjects With Chronic Fatigue Syndrome | July 2010 | October 2011 |
| NCT01730495 | Terminated | Phase 2 | Tumor Necrosis Factor-alpha Inhibition Using Etanercept in Chronic Fatigue Syndrome | October 2012 | August 2014 |
| NCT05397626 | Unknown status | Phase 1 | Biofeedback and Hydrogen Water as Treatments for Chronic Fatigue Syndrome | May 23, 2022 | May 23, 2023 |
| NCT00071162 | Unknown status | Genetics of Fibromyalgia | September 1999 | ||
| NCT04100915 | Unknown status | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in ME/CFS | March 2, 2020 | July 2023 | |
| NCT01793415 | Unknown status | Phase 1/Phase 2 | Treatment of Chronic Fatigue Syndrome (CFS) With Iodinated Activated Charcoal (IodoCarb®) | February 2013 | December 2013 |
| NCT04593225 | Unknown status | N/A | Effectiveness of VIRTUAL SFCAMINA STUDY | April 21, 2020 | January 21, 2022 |
| NCT01893619 | Unknown status | Observational Research on Use of Immunoprop Supplement in Chronic Fatigue Syndrome | June 2013 | December 2013 | |
| NCT01908036 | Unknown status | Use of a Monitor in ME/CFS | July 2013 | December 2013 | |
| NCT04667611 | Unknown status | Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study | March 9, 2020 | December 2023 | |
| NCT02847845 | Unknown status | N/A | A Clinical Study About Improvement of Chronic Fatigue After Taking Red Ginseng | June 2016 | June 2017 |
| NCT02854683 | Unknown status | Phase 1 | Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients | February 2016 | December 2021 |
| NCT02924831 | Unknown status | Phase 2 | High-tech Acupuncture for Treatment of Chronic Fatigue Syndrome | November 2016 | July 2018 |
| NCT02948556 | Unknown status | ME/CFS: Activity Patterns and Autonomic Dysfunction | June 2016 | May 2020 | |
| NCT02964533 | Unknown status | N/A | Thunder-Fire Moxibustion Therapy for Chronic Fatigue Syndrome on Shenque Acupoint: a Randomized Controlled Trial | November 2016 | |
| NCT05273372 | Unknown status | N/A | RESTORE ME -- RCT of Oxaloacetate on Improving Fatigue in ME/CFS | March 15, 2022 | December 31, 2022 |
| NCT03254823 | Unknown status | Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | March 28, 2018 | September 30, 2020 | |
| NCT03331419 | Unknown status | Exercise-related Post-exertional Malaise | November 2017 | October 2018 | |
| NCT03502044 | Unknown status | N/A | New MRT Imaging Biomarkers and Treatment With Kinetic Oscillatory Stimulation (KOS) in Nasal Cavity for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | April 17, 2018 | June 15, 2020 |
| NCT01584934 | Withdrawn | Phase 4 | Sodium Oxybate in Patients With Chronic Fatigue Syndrome. | June 2013 | December 2015 |
| NCT04870476 | Withdrawn | N/A | Feasibility and Acceptability of the Internet-delivered Treatment "One Step at the Time" for Bodily Distress Syndrome | September 19, 2021 | November 15, 2021 |
| NCT01872351 | Withdrawn | Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder | November 2011 | November 2012 | |
| NCT01471652 | Withdrawn | Phase 2 | Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder | March 2012 | February 2013 |
| NCT03849326 | Withdrawn | N/A | Chronic Fatigue Etiology in Intensive Care Unit Survivors: the Role of Neuromuscular Function | December 2023 | April 2025 |
- Disase is a (Disease Ontology)
- DOID:225
- Cross Reference ID (Disease Ontology)
- GARD:7121
- Cross Reference ID (Disease Ontology)
- ICD10CM:G93.32
- Cross Reference ID (Disease Ontology)
- ICD9CM:780.71
- Cross Reference ID (Disease Ontology)
- MESH:D015673
- Cross Reference ID (Disease Ontology)
- NCI:C3037
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:193054000
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0015674
- Exact Synonym (Disease Ontology)
- CFS
- Exact Synonym (Disease Ontology)
- Myalgic encephalitis
- Exact Synonym (Disease Ontology)
- Myalgic encephalomyelitis
- Exact Synonym (Disease Ontology)
- Postviral fatigue syndrome