tropical spastic paraparesis

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Information
Disease name
tropical spastic paraparesis
Disease ID
DOID:321
Description
"A viral infectious disease that results in inflammation located in spinal cord, has_material_basis_in Human T-lymphotropic virus 1, which is transmitted by sexual contact, and transmitted by breast feeding. The infection has symptom spastic weakness of both legs, has symptom muscle stiffness, has symptom sensory disturbance, and has symptom spasms." [url:http\://en.wikipedia.org/wiki/Tropical_spastic_paraparesis, url:http\://www.merckmanuals.com/professional/sec16/ch224/ch224k.html]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00034723 Completed MRI Brain Studies in Patients With HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis April 2002 March 2004
NCT02655471 Completed Early Phase 1 Effect of Raltegravir in Patients With Acute Tropical Spastic Paraparesis - Human T-Lymphotropic Virus 1 Infection July 1, 2017 March 15, 2019
NCT00001785 Completed Phase 2 Recombinant Human Interferon Beta-1a (Avonex) for the Treatment of Patients With HTLV-1-Associated Myelopathy (HAM) September 1998 September 2004
NCT00001156 Completed Assessment of Patients With Multiple Sclerosis (MS) January 23, 1976 February 1, 2010
NCT01472263 Completed Phase 3 Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases September 2009 September 2012
NCT01651819 Completed N/A Urological Physical Therapy in HTLV-1 With Urinary Symptoms March 1, 2012 July 30, 2015
NCT00001778 Recruiting Evaluation of Patients With HAM/TSP April 6, 1998
Disase is a (Disease Ontology)
DOID:934
Cross Reference ID (Disease Ontology)
ICD10CM:G04.1
Cross Reference ID (Disease Ontology)
MESH:D015493
Cross Reference ID (Disease Ontology)
MIM:159580
Cross Reference ID (Disease Ontology)
NCI:C179058
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:45129002
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0030481
Exact Synonym (Disease Ontology)
HTLV-associated myelopathy
Exact Synonym (Disease Ontology)
Tropical spastic paralysis
Exact Synonym (Disease Ontology)
Tropical spastic paraplegia
OrphaNumber from OrphaNet (Orphanet)
289326