Annotation Detail

Information
Associated Genes
IL10
Associated Variants
IL10 MUTATION
IL10 MUTATION
Associated Disease
leishmaniasis
Source Database
DisGeNET
Description
The redirection of the immune response elicited against the LiPABP family (from IL-10 towards IFN-γ mediated responses) by genetic vaccination was able to induce a partial protection against the development of the disease in a highly susceptible murine model of leishmaniasis.
Pubmed
25955652
Section of the abstract supporting the evidence
CONCLUSION/SIGNIFICANCE
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.125991584229095
Drugs