leishmaniasis

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Information
Disease name
leishmaniasis
Disease ID
DOID:9065
Description
"A parasitic protozoa infectious disease that involves infection caused by protozoan parasite of the genus Leishmania, which is transmitted by the bite of sand fly (subfamily Phlebotominae)." [url:http\://www.cdc.gov/ncidod/dpd/parasites/leishmania/factsht_leishmania.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02530697 Active, not recruiting Phase 2 The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil August 2015 August 2026
NCT00004755 Completed Phase 2 Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Brazil September 1995
NCT00373568 Completed Phase 1/Phase 2 Miltefosine (Long Course) for Bolivian Mucosal Leishmaniasis April 2005 December 2007
NCT00373776 Completed Phase 1/Phase 2 Miltefosine for Mucosal Leishmaniasis April 2004 May 2006
NCT00401297 Completed Th1/Th2 Polarization and Linkage to L. Viannia Infection Outcomes December 2006 April 2010
NCT00401349 Completed Expression of Mif Alleles in Individuals With Leishmaniasis December 2006 April 2010
NCT00401557 Completed Mechanisms Relating to the Distinct in Vitro Susceptibility of Human Macrophages to L. Viannia Infection December 2006 April 2010
NCT00657618 Completed Phase 1/Phase 2 Use of Sodium Stibogluconate as a Treatment for Leishmaniasis October 2004 April 2015
NCT00662012 Completed Phase 2 Sodium Stibogluconate Treatment of Leishmaniasis June 2002 December 2007
NCT01300975 Completed Phase 2 Intralesional Antimony for Bolivian Cutaneous Leishmaniasis January 2011 July 2012
NCT01377974 Completed Phase 2 Clinical Trial of Miltefosine to Treat Mucosal Leishmaniasis July 2009 December 2014
NCT00001169 Completed Clinical Investigation of Infections Due to Leishmanial Parasites December 1979 February 2001
NCT01484548 Completed Phase 1 Phase 1 LEISH-F3 Vaccine Trial in Healthy Adult Volunteers January 2012 May 2013
NCT01751048 Completed Phase 1 LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccine March 2013 January 2015
NCT02656797 Completed Phase 2 Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis January 30, 2018 October 1, 2021
NCT03294161 Completed Phase 2 Fourth-generation Immucillin Derivative DI4G Associated Therapy in Cutaneous Leishmaniasis December 2014 June 2017
NCT03641339 Completed N/A Defining Skin Immunity of a Bite of Key Insect Vectors in Humans September 5, 2018 May 20, 2020
NCT03993093 Completed Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART Centre June 1, 2019 March 15, 2020
NCT04504435 Completed Phase 1 Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy Participants September 29, 2020 January 11, 2024
NCT04512742 Completed N/A A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand Flies October 16, 2021 November 1, 2023
NCT05449717 Recruiting Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan May 31, 2022 May 31, 2026
NCT00344188 Recruiting Diagnosis and Treatment of Leishmania Infections November 30, 2001
NCT03784248 Recruiting Mediterranean Visceral Leishmaniasis With Leishmania Infantum July 3, 2019 August 15, 2024
NCT06307171 Recruiting N/A Human Leishmaniasis: Antigen Recognition Pattern and Study of New Potential Biomarkers May 22, 2023 November 2026
NCT06124144 Terminated Phase 1 Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adults June 21, 2023 February 27, 2024
NCT03874234 Terminated Phase 1 Safety, Tolerability and Pharmacokinetics (PKs) Investigation of GSK3186899 in Healthy Subjects April 30, 2019 October 17, 2019
NCT03009422 Unknown status N/A Fractional CO2 Laser With Topical Pentostam Treatment for Cutaneous Leishmaniasis. November 2014 June 2017
NCT02429505 Withdrawn Treatment of Leishmaniasis With Impavido® (Miltefosine): Higher-Weight Patient Registry July 2015 March 2020
NCT01437020 Withdrawn Phase 1/Phase 2 SCH708980 With and Without AmBisome for Visceral Leishmaniasis
Disase is a (Disease Ontology)
DOID:2789
Cross Reference ID (Disease Ontology)
GARD:6881
Cross Reference ID (Disease Ontology)
ICD10CM:B55
Cross Reference ID (Disease Ontology)
ICD9CM:085
Cross Reference ID (Disease Ontology)
MESH:D007896
Cross Reference ID (Disease Ontology)
NCI:C34767
Cross Reference ID (Disease Ontology)
ORDO:507
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:266206004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0023281
Disase Synonym (Disease Ontology)
Post Kala-Azar Dermal Leishmaniasis
Disase Synonym (Disease Ontology)
post-kala-azar dermal infectious disease by leishmaniasis
Disase Synonym (Disease Ontology)
Post-kala-azar dermal leishmaniasis
OrphaNumber from OrphaNet (Orphanet)
507
ICD10 preferred id (Insert disease from ICD10)
D0000741
ICD10 class code (Insert disease from ICD10)
B55
MeSH unique ID (MeSH (Medical Subject Headings))
D007896