Delirium
Information
- Disease name
- Delirium
- Disease ID
- Description
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| NDUFS4 | 5 | 53,560,639 | 53,683,338 | 4 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04099472 | Active, not recruiting | N/A | Partnering With Family Members to Prevent, Detect and Manage Delirium in Critically Ill Patients. | January 13, 2020 | February 8, 2024 |
| NCT05638945 | Active, not recruiting | N/A | Determining the Preliminary Efficacy of the Emergency Department Delirium Screening and Detection Program | November 28, 2022 | May 2024 |
| NCT05299346 | Active, not recruiting | Post-ICU Follow-up Study in Covid-19 Patients | October 1, 2020 | June 1, 2023 | |
| NCT03624595 | Active, not recruiting | N/A | Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery | April 16, 2019 | August 2024 |
| NCT03480061 | Active, not recruiting | Phase 4 | Dexmedetomidine to Reduce the Incidence of POCD After Open Cardiac Surgery | August 9, 2018 | December 2024 |
| NCT03928236 | Active, not recruiting | N/A | Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium | November 18, 2019 | April 30, 2024 |
| NCT03098459 | Active, not recruiting | Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study | November 2, 2017 | October 2027 | |
| NCT03021486 | Active, not recruiting | Phase 2/Phase 3 | Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer | June 5, 2017 | June 30, 2025 |
| NCT03019133 | Active, not recruiting | N/A | Trial to Evaluate the Effects of Sound Modulation on Critically Ill Patients | December 2016 | December 31, 2024 |
| NCT04742673 | Active, not recruiting | Phase 2 | Maximizing trEatment of Neurological Dysfunction Using INtravenous Guanfacine Study | May 4, 2021 | December 31, 2025 |
| NCT05606328 | Active, not recruiting | N/A | Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program | February 28, 2023 | May 2024 |
| NCT03905668 | Active, not recruiting | Fundamental Intelligent Building Blocks of the Intensive Care Unit (ICU) of the Future: Intelligent ICU of the Future | February 3, 2016 | July 2024 | |
| NCT03392376 | Active, not recruiting | Phase 4 | Agents Intervening Against Delirium in Intensive Care Unit | June 13, 2018 | July 2023 |
| NCT03385993 | Active, not recruiting | N/A | Digital Rehabilitation Environment Augmenting Medical System | January 16, 2018 | December 2024 |
| NCT06176625 | Active, not recruiting | N/A | Sight and Hearing Investigation Into Effects on Delirium | January 11, 2023 | August 31, 2024 |
| NCT04602988 | Active, not recruiting | Study to Assess and Monitor Brain Activity | August 10, 2020 | August 2025 | |
| NCT03182335 | Active, not recruiting | Vasopressor SAT Study | April 28, 2014 | June 2024 | |
| NCT03840577 | Active, not recruiting | N/A | BIS-Guided Sedation in Critically Ill Patients Under Deep Sedation | April 1, 2019 | January 1, 2024 |
| NCT03743649 | Active, not recruiting | Phase 2/Phase 3 | Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care | July 17, 2019 | December 31, 2026 |
| NCT00392795 | Active, not recruiting | The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors | January 2007 | December 2025 | |
| NCT02465307 | Active, not recruiting | Intelligent Intensive Care Unit | February 2016 | May 30, 2025 | |
| NCT04247646 | Active, not recruiting | N/A | SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty | October 1, 2020 | December 31, 2028 |
| NCT02299037 | Active, not recruiting | Predicting the Risk of Post-operative Delirium: Use of Neuropsychology, Serum and CSF Biomarkers and Genetics to Predict Risk of Post-operative Delirium | March 2012 | February 2025 | |
| NCT03147937 | Active, not recruiting | Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2) | May 1, 2017 | December 2024 | |
| NCT00699946 | Completed | N/A | Prophylactic Olanzapine Versus Placebo for Prevention of Postoperative Delirium After Joint Replacement Surgery | January 2005 | October 2007 |
| NCT00714194 | Completed | Early Phase 1 | Effect of Daily Interruption of Continuous Sedation on Delirium, Sleep Perception in Intensive Care Unit (ICU) Patients | July 2008 | September 2009 |
| NCT00784576 | Completed | Incidence and Predictors of Delirium After Cardiac Surgery | November 2004 | October 2008 | |
| NCT00791648 | Completed | N/A | Short-term Atorvastatin's Effect on Acute Kidney Injury Following Cardiac Surgery | July 2009 | December 2014 |
| NCT00819988 | Completed | Phase 3 | Pregabalin in the Prevention of Postoperative Delirium and Pain | May 2009 | October 2011 |
| NCT00835159 | Completed | Phase 4 | Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial | December 2008 | October 2010 |
| NCT00842608 | Completed | N/A | Pharmacological Management of Delirium | February 2009 | July 2015 |
| NCT00873379 | Completed | Phase 3 | Melatonin Supplementation for Delirium Prevention in Acutely Hospitalized Elderly | October 2007 | March 2008 |
| NCT00911677 | Completed | Does APOE-e4 Predict Delirium and Cognitive Dysfunction After Surgery? | August 2005 | May 2009 | |
| NCT00919698 | Completed | Delirium in Mechanically Ventilated Patients | June 2010 | October 2013 | |
| NCT00991913 | Completed | Risk Factors of Recovery Room Delirium After Elective Non-cardiovascular Surgery | June 1, 2010 | June 30, 2010 | |
| NCT01009268 | Completed | N/A | The Effect of a Pre- and Postoperative Orthogeriatric Service | September 2009 | December 2012 |
| NCT01029080 | Completed | Cerebrovascular Autoregulation During Sepsis | December 2009 | March 2011 | |
| NCT01136148 | Completed | N/A | Trial of a Medical and Mental Health Unit for Older People | July 2010 | June 2012 |
| NCT01151865 | Completed | Phase 2/Phase 3 | Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation | February 2011 | December 2013 |
| NCT01162343 | Completed | Delirium in the Emergency Department: Novel Screening | July 2009 | February 2012 | |
| NCT01187667 | Completed | Evaluation of Delirium Prevention in Critically Ill Patients | August 2010 | October 2011 | |
| NCT01199276 | Completed | Phase 2 | Hip Fracture Surgery in Elderly Patients | September 2010 | October 2014 |
| NCT01211522 | Completed | Phase 3 | The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study | December 14, 2011 | July 19, 2018 |
| NCT01249755 | Completed | International Validation of a Delirium Prediction Model for ICU Patients | November 2011 | August 2012 | |
| NCT01267682 | Completed | Phase 2 | Cognitive Intervention For Delirium in Dementia | January 2011 | March 2016 |
| NCT01274819 | Completed | N/A | Dynamic Light Application to Prevent ICU Acquired Delirium | July 2011 | September 2013 |
| NCT01278524 | Completed | International Multicenter Study One Day Prevalence Observational Study for Delirium on ICU | January 2011 | January 2011 | |
| NCT01280097 | Completed | Study of Sleep and Delirium in the Intensive Care Unit (ICU) | December 2010 | November 2012 | |
| NCT01291368 | Completed | Sedation Influence on Delirium and Post-traumatic Stress-disorder as a Result of Hospitalization in Intensive Care | September 2009 | February 2012 | |
| NCT01322672 | Completed | Peri-Anesthetic Imaging of Cognitive Dysfunction | March 2011 | August 27, 2015 | |
| NCT01356810 | Completed | N/A | Prophylactic Environmental Management of Delirium | September 2009 | June 2010 |
| NCT01362270 | Completed | N/A | Acupuncture for Sedation in the Intensive Care Unit (ICU) | July 2011 | July 2015 |
| NCT01362959 | Completed | Phase 4 | Nicotine Replacement Therapy in the Intensive Care Unit | June 2012 | August 2016 |
| NCT01378741 | Completed | N/A | Reducing Delirium After Cardiac Surgery: A Multifaceted Approach Of Perioperative Care | April 2011 | April 2015 |
| NCT01487317 | Completed | Phase 3 | Rivastigmine in the Management of Delirium | June 2011 | February 2016 |
| NCT01505465 | Completed | N/A | Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery | February 2012 | June 2013 |
| NCT01530308 | Completed | Phase 4 | Haloperidol Prophylaxis in Older Emergency Department Patients | November 2012 | October 2015 |
| NCT01539733 | Completed | N/A | Early Recognition and Optimal Treatment of Delirium in Patients With Advanced Cancer | March 2010 | April 2017 |
| NCT01555996 | Completed | N/A | Early Occupational Therapy for Delirium Prevention in Older Patients Admitted to Critical Care Unit | April 2011 | December 2012 |
| NCT01574950 | Completed | Impact of Impaired Cerebral Autoregulation on Postoperative Delirium in Elderly Patients Undergoing Spine Surgery | March 2012 | June 2014 | |
| NCT01616914 | Completed | Subclinical Delirium and Clinical Outcome | January 2010 | August 2012 | |
| NCT01628185 | Completed | Pain Assessment in the Intensive Care Unit | January 2012 | July 2014 | |
| NCT01651897 | Completed | Delirium in the Emergency Department and Its Extension Into Hospitalization | March 1, 2012 | April 30, 2015 | |
| NCT02206880 | Completed | The Delirium-CS Canada Study | November 2014 | July 2018 | |
| NCT00095251 | Completed | Phase 2 | MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status | August 2004 | December 2016 |
| NCT00096863 | Completed | Phase 2 | The MIND Study: Modifying the INcidence of Delirium | December 2004 | July 2007 |
| NCT00182832 | Completed | N/A | e-CHAMP: Enhancing Care for Hospitalized Older Adults With Memory Problems | June 2006 | December 2008 |
| NCT00182845 | Completed | Phase 4 | Donepezil in the Prevention of Post-Operative Cognitive Decline | February 2005 | April 2007 |
| NCT00182884 | Completed | Phase 4 | Donepezil in Preventing Delirium in Hospitalized Elderly | July 2004 | April 2007 |
| NCT00182936 | Completed | Phase 3 | A Trial to Reduce Delirium in Aged Post Acute Patients | May 2000 | June 2004 |
| NCT00257868 | Completed | Phase 3 | Rivastigmine for the Prevention of Postoperative Delirium in Patients Undergoing Cardiac Surgery | January 2006 | July 2007 |
| NCT00351299 | Completed | Phase 2 | Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium | January 2006 | October 2012 |
| NCT00400062 | Completed | MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care | July 1, 2007 | December 1, 2017 | |
| NCT00400790 | Completed | N/A | Organ Protection for Coronary Artery Bypass Graft (CABG): Propofol Versus Desflurane | September 2007 | January 2010 |
| NCT00409370 | Completed | Phase 3 | Trial of Safety Nets In Hospitalized Patients | April 2003 | February 2005 |
| NCT00417664 | Completed | Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients | April 2002 | April 2004 | |
| NCT00429676 | Completed | Phase 2 | Pilot Study of Haloperidol to Treat Critical Illness Delirium | December 2005 | September 2007 |
| NCT00469482 | Completed | N/A | The SOMNUS Study: Sedative Optimization Via Monitoring Neurological Status | June 2007 | September 2016 |
| NCT00493714 | Completed | Delirium Recall in Advanced Cancer Patients | July 2005 | December 2007 | |
| NCT00505804 | Completed | Phase 2 | A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium | January 2005 | November 2008 |
| NCT00507481 | Completed | Evaluation of Risk Factors of Sleep Quality in Intensive Care Unit | January 2006 | September 2007 | |
| NCT00533884 | Completed | Neurocognitive Functioning in Patients With Newly Diagnosed Upper Aerodigestive Tract Cancer Receiving Treatment at Henry-Joyce Cancer Clinic | October 2007 | June 2013 | |
| NCT00564434 | Completed | Postoperative Delirium in Hip Fracture Patients | May 2005 | January 2007 | |
| NCT00586196 | Completed | Phase 2 | Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period | January 2007 | February 2013 |
| NCT00590707 | Completed | N/A | Post-Operative Delirium in Elderly Surgical Patients | January 2005 | May 2017 |
| NCT00604773 | Completed | Incidence of Delirium in Critically Ill Patients in a Dutch University Hospital | February 2008 | February 2009 | |
| NCT00693121 | Completed | Phase 4 | Amantadine for Treatment of Symptoms of the Post-traumatic Confusional State | April 2003 | March 2019 |
| NCT01690988 | Completed | Phase 3 | The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial | February 1, 2014 | July 2017 |
| NCT01720914 | Completed | Instruments for Delirium Assessment Regarding to Analgesia Sedation and Ventilator Status | November 2012 | December 2015 | |
| NCT01739933 | Completed | Phase 3 | The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure | May 15, 2013 | July 2019 |
| NCT01774240 | Completed | N/A | Incidence, Severity and Treatment of Delirium in Cardiac Surgery Patients: A Before-after Study | April 2012 | December 2012 |
| NCT01775982 | Completed | Validation of a French Version of the Confusion Assessment Method (CAM) | April 2014 | February 2, 2016 | |
| NCT01785290 | Completed | Phase 4 | pRophylactic halopEriDol Use for Delirium in iCu patiEnts With a High Risk for Delirium | June 2013 | March 2017 |
| NCT01791296 | Completed | Phase 4 | Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients? | January 2011 | December 2016 |
| NCT01811459 | Completed | Phase 3 | Trial Comparing Haloperidol, Quetiapine and Placebo in the Pharmacological Treatment of Delirium | February 2013 | September 2016 |
| NCT01816685 | Completed | N/A | Effect of CPAP on Postoperative Delirium | June 2013 | June 2014 |
| NCT01827501 | Completed | N/A | Avoidance of Delirium in Older Patients After Major Non-cardiac Surgery | April 2013 | February 2021 |
| NCT01836302 | Completed | Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study) | August 2012 | December 2013 | |
| NCT01902277 | Completed | ICU Delirium: a One-week Snapshot of Burden Across the Eastern UK Region | June 2012 | July 2012 | |
| NCT01904760 | Completed | Phase 4 | Dexmedetomidine to Prevent Agitation After Free Flap Surgery | June 2013 | |
| NCT01916889 | Completed | N/A | 4-question "RACY" Delirium Screening Tool Validation Study | September 2013 | April 2015 |
| NCT01980251 | Completed | Delirium, Electroencephalographic Alterations and Cortical Spreading Depression (CSD) in Critical Illness | October 2013 | September 2015 | |
| NCT01982656 | Completed | N/A | Massage Technique for Pain, Anxiety and Delirium in SAH Patients | December 2013 | February 22, 2018 |
| NCT01983384 | Completed | N/A | Anesthetic Depth and Postoperative Delirium Trial - 2 | July 2015 | October 2017 |
| NCT01998997 | Completed | N/A | A Family Intervention for Delirium Prevention | March 2014 | December 2014 |
| NCT02032030 | Completed | Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys | July 2012 | October 21, 2020 | |
| NCT02035436 | Completed | N/A | Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Me-chanical Ventilation - Effects on Cognitive Function | January 2014 | March 2019 |
| NCT02045004 | Completed | Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfunction | July 14, 2015 | November 2018 | |
| NCT02054169 | Completed | Feasibility of the Modified Confusion Assessment Method for the Emergency Department (mCAM-ED) | August 2013 | ||
| NCT02068170 | Completed | Risk of QT-prolongation and Torsade de Pointes in Patients Treated With Acute Medication in a University Hospital | February 2014 | June 2015 | |
| NCT02084394 | Completed | Cerebral Blood Flow During CPB During Cardiac Surgery and the Presence of Post op Delirium | June 2013 | February 2016 | |
| NCT02086981 | Completed | The DETEcT Study - Delirium in Elderly paTiEnts Admitted to Trauma | February 2014 | January 2015 | |
| NCT02096068 | Completed | Phase 4 | Neuroprotection With Dexmedetomidine in Patients Undergoing Elective Cardiac or Abdominal Surgery (Neuprodex) | July 2014 | July 2018 |
| NCT02131545 | Completed | Phase 1 | Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine | June 2014 | July 2016 |
| NCT02190903 | Completed | N/A | A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia | October 2013 | April 2015 |
| NCT00006349 | Completed | Phase 3 | Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer | February 2001 | January 2007 |
| NCT02213900 | Completed | Phase 4 | Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy | September 2013 | December 2015 |
| NCT02230605 | Completed | N/A | Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial) | July 2015 | August 20, 2019 |
| NCT02267538 | Completed | Phase 4 | Dexmedetomidine and Delirium in Patients After Cardiac Surgery | November 2014 | November 2015 |
| NCT02275182 | Completed | Phase 4 | Impact of Dexmedetomidine on the Post-Operative Cognition Dysfunction(POCD) in Geriatric Patients | October 2014 | February 20, 2017 |
| NCT02315846 | Completed | Acetylcholinesterase in Postoperative Delirium | January 2014 | July 2014 | |
| NCT02323984 | Completed | Postoperative Delirium in Hip Arthroplasty Patients | January 2014 | March 2016 | |
| NCT02324153 | Completed | Phase 2 | Ramelteon in the Prevention of Post-operative Delirium | March 24, 2017 | June 26, 2019 |
| NCT02344043 | Completed | Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness | March 2014 | September 2016 | |
| NCT02356523 | Completed | Incidence and Prognostic Value of Delirium in Patients With Acute Coronary Syndromes | January 2014 | October 2015 | |
| NCT02374177 | Completed | The Effects of Anaesthetic Agents on Postoperative Delirium | November 2014 | February 2015 | |
| NCT02382445 | Completed | N/A | Anesthesia Depth Increases the Degree of Postoperative Dementia, Delirium, and Cognitive Dysfunction | January 2014 | May 8, 2017 |
| NCT02383004 | Completed | N/A | Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube Placement | February 2015 | November 2016 |
| NCT02400892 | Completed | Patent Foramen Ovale and the Risk of Postoperative Delirium Following Elective Hip and Knee Arthroplasty Surgeries | March 2015 | June 2016 | |
| NCT02404181 | Completed | Validation of a Delirium Monitor | March 2014 | December 1, 2016 | |
| NCT02413554 | Completed | Phase 4 | Rivastigmine Patch Effect on the Post-operative Delirium in Patients at Risk of Dementia. | April 2013 | April 2015 |
| NCT02466373 | Completed | Phase 3 | Pharmacokinetics and Clinical Effects of Escalating Doses of Clonidine in ICU Patients | December 2016 | April 5, 2018 |
| NCT02481115 | Completed | Validation of the PreSchool Confusion Assessment Method for the Intensive Care Unit (psCAM-ICU) | February 2013 | October 2014 | |
| NCT02518646 | Completed | DElirium prediCtIon in the intenSIve Care Unit: Head to Head comparisON of Two Delirium Prediction Models | September 2015 | December 2016 | |
| NCT02532530 | Completed | N/A | Peri-operative Monitoring of Cerebral Oxygenation and the Onset of Delirium in Patients Undergoing Cardiac Surgery | June 2015 | March 1, 2018 |
| NCT02536417 | Completed | Phase 3 | Efficacy of Melatonin in Decreasing the Incidence of Delirium in End of Life Patients | June 29, 2016 | September 2020 |
| NCT02546765 | Completed | Phase 4 | Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery | October 2015 | July 2019 |
| NCT02548923 | Completed | Phase 4 | Dexmedetomidine Versus Propofol for Prolonged Sedation in Critically Ill Trauma and Surgical Patients | November 2014 | April 2015 |
| NCT02548975 | Completed | Risk Factors for Delirium Following Cardiac Surgery | November 2009 | November 2016 | |
| NCT02554253 | Completed | Phase 2 | The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction | September 2015 | December 2020 |
| NCT02558777 | Completed | N/A | Pilot Study of a Multicomponent Nurse Intervention to Reduce Delirium in Hospitalized Older Adults | October 2013 | February 2014 |
| NCT02574234 | Completed | N/A | Influence of Apelin Levels on Postoperative Cognitive Disorders After Orthopedic Surgery in Elderlies (APOCOGNIT) | March 30, 2016 | March 12, 2018 |
| NCT02587039 | Completed | N/A | An Intervention to Reduce Delirium After Cardiac Surgery | June 2014 | December 2015 |
| NCT02590796 | Completed | Validating Studies to Assess the Diagnostic Accuracy of a Software Application for Detection and Monitoring of Attentional Deficits in Delirium | October 12, 2015 | March 22, 2018 | |
| NCT02594982 | Completed | N/A | DANish DELIrium Study On Neurointensive Care Patients | August 2015 | July 2016 |
| NCT02597231 | Completed | Phase 1/Phase 2 | Melatonin and Sleep in Preventing Delirium in the Hospital | November 2015 | December 31, 2016 |
| NCT02599428 | Completed | Recovery After ICU Treatment: A Prospective Cohort Study | February 2016 | May 2018 | |
| NCT02603380 | Completed | Feasibility of a Software App for Testing Inattention in Delirium | March 2015 | June 2015 | |
| NCT02603731 | Completed | Delirium at the Intensive Care Unit - a Retrospective Cohort Study | August 2015 | February 2016 | |
| NCT02628925 | Completed | Nu-DESC DK: The Danish Version of the Nursing Delirium Screening Scale | September 2014 | April 2015 | |
| NCT02662257 | Completed | N/A | Impact of Anesthesia Maintenance Methods on Incidence of Postoperative Delirium | April 1, 2015 | November 26, 2017 |
| NCT02681731 | Completed | Impact of Neuromonitoring During Cardiac Procedures | March 2016 | December 31, 2017 | |
| NCT02688179 | Completed | Neuroinflammation and Postoperative Delirium in Cardiac Surgery | January 2016 | March 2017 | |
| NCT02706522 | Completed | N/A | Effect of Oral Carbohydrate on Serum S-100β Protein and Development of Postoperative Delirium in Elderly Patients | October 24, 2016 | January 26, 2017 |
| NCT02708823 | Completed | Standardization of a Novel Self-administered Tablet Computer-based Clinical Screening Tool for Adverse Postoperative Cognitive Outcomes | December 2016 | April 2017 | |
| NCT02743689 | Completed | Perioperative Risk Factors for Intensive Care Delirium After Cardiac Surgery | March 2015 | ||
| NCT02761330 | Completed | N/A | Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia | April 2016 | September 11, 2019 |
| NCT02782143 | Completed | Testing the Validity of the "Modified Confusion Assessment Method for the Emergency Department" (mCAM-ED)" | November 2015 | September 2016 | |
| NCT02809937 | Completed | Phase 4 | Dexmedetomidine and Long-term Outcome in Elderly Patients After Surgery | May 2011 | June 2017 |
| NCT02838706 | Completed | Elderly With Hip Fracture and Perioperative Hemoglobin and Perfusion Index Levels | May 2016 | December 1, 2016 | |
| NCT02863081 | Completed | Helping Older Persons Emerge Stronger | July 2016 | July 1, 2017 | |
| NCT02890927 | Completed | N/A | Geriatric-CO-mAnagement for Cardiology Patients in the Hospital | September 2016 | July 2019 |
| NCT02908464 | Completed | N/A | Prevention of Early Postoperative Decline | November 2016 | September 2019 |
| NCT02926417 | Completed | Interventions for Postoperative Delirium: Biomarker-2 (IPOD-B2) | June 2016 | November 26, 2019 | |
| NCT02932358 | Completed | N/A | Effectiveness and Safety of a Flexible Family Visitation Model for Delirium Prevention in Adult Intensive Care Units: a Cluster-randomized, Crossover Trial (The ICU Visits Study) | April 28, 2017 | June 22, 2018 |
| NCT02954861 | Completed | A Study to Identify the Incidence of Post Traumatic Stress Symptoms in Patients With Delirium Following Cardiac Surgery | April 7, 2016 | May 10, 2018 | |
| NCT02963961 | Completed | N/A | Cognitive Training for the Prevention of Postoperative Delirium | April 6, 2017 | May 18, 2018 |
| NCT02964221 | Completed | Cognitive Changes After Major Joint Replacement | June 15, 2016 | May 1, 2017 | |
| NCT02978352 | Completed | N/A | A Comparison of Learning Method (CAM-ICU) Between E-learning and Conventional Face-to-face Lecture and Demonstration | January 2017 | March 2017 |
| NCT02979782 | Completed | Neurological Outcome After Minimal Invasive Coronary Artery Bypass Graft | December 2016 | August 2018 | |
| NCT02994979 | Completed | N/A | Nursing Assistant Intervention to Prevent Delirium in Nursing Homes | November 2016 | August 28, 2018 |
| NCT03002701 | Completed | N/A | The Impact of Nursing Delirium Preventive Interventions in the Intensive Care Unit | December 31, 2016 | May 31, 2020 |
| NCT03012984 | Completed | N/A | Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium | January 6, 2017 | June 11, 2022 |
| NCT03023839 | Completed | Incidence and Risk Factors for Delirium in Severely Injured Patients | February 2015 | January 2017 | |
| NCT03050021 | Completed | Risk Factors for Delirium in Critically Ill Surgical Patients | April 1, 2013 | August 30, 2015 | |
| NCT03064308 | Completed | N/A | The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery | June 26, 2017 | July 27, 2018 |
| NCT03066232 | Completed | Delirium in Home-dwelling Old People Receiving Home Nursing Care | May 11, 2015 | July 8, 2018 | |
| NCT03078946 | Completed | Phase 4 | Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery | March 2013 | April 2015 |
| NCT03095417 | Completed | N/A | Improving the Recovery and Outcome Every Day After the ICU | September 25, 2017 | December 15, 2022 |
| NCT03095443 | Completed | N/A | Decreasing Delirium Through Music | December 1, 2016 | December 31, 2018 |
| NCT03098472 | Completed | Cholinesterase Activity and DeliriUm During Critical Illness Study | May 8, 2017 | February 1, 2021 | |
| NCT03110185 | Completed | N/A | Postoperative Delirium: Brain Vulnerability and Recovery | November 25, 2015 | March 8, 2019 |
| NCT03125252 | Completed | N/A | Impact of Non-pharmacological Prevention Measures on the Incidence of Delirium in Adult Intensive Care Units | October 27, 2016 | November 2020 |
| NCT03128671 | Completed | N/A | Family Automated Voice Reorientation Study | May 19, 2017 | May 17, 2021 |
| NCT03133845 | Completed | N/A | Shaping Anesthetic Techniques to Reduce Post-operative Delirium | October 2015 | May 25, 2020 |
| NCT03133858 | Completed | Longitudinal Cohort Study - for the Treatment of Acute Postoperative Pain and Postoperative Delirium, Postoperative Cognitive Dysfunctions, and Chronic Pain. | November 9, 2017 | November 28, 2021 | |
| NCT03194360 | Completed | Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit | December 1, 2015 | January 15, 2017 | |
| NCT03199768 | Completed | Delirium in Geriatric Hospital Single-bed and Multibed Rooms | September 15, 2016 | December 31, 2017 | |
| NCT03199859 | Completed | Early Diagnosis and Treatment Standardization of Delirium | May 17, 2016 | December 31, 2018 | |
| NCT03246165 | Completed | Predictive Factors and Complications of Delirium | September 1, 2011 | June 30, 2015 | |
| NCT03251651 | Completed | N/A | Intraoperative Sedatives and Postoperative Deilirium | June 15, 2017 | October 15, 2021 |
| NCT03252054 | Completed | Memory and Attention Disorders and Malnutrition in Hospital Setting | September 1, 2016 | May 31, 2018 | |
| NCT03263442 | Completed | Phase 2 | High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation | October 16, 2017 | August 10, 2020 |
| NCT03273335 | Completed | Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults | June 15, 2017 | October 21, 2022 | |
| NCT03277118 | Completed | Quantifying Activity Using Wireless Wearable Technology | April 18, 2017 | August 18, 2019 | |
| NCT03287401 | Completed | Prediction of PACU Delirium Using EEG - German Validation Study | September 19, 2017 | December 6, 2019 | |
| NCT03293550 | Completed | Can a New EEG Based Tool Predict Post-operative Delirium and Cognitive Dysfunction? | December 31, 2017 | September 6, 2020 | |
| NCT03313115 | Completed | Sleep/Wake Protocol Implementation to Improve Sleep Quality in the ICU | October 11, 2017 | March 14, 2018 | |
| NCT03317067 | Completed | Phase 3 | Effects of Dexmedetomidine on Delirium Duration of Non-intubated ICU Patients (4D Trial) | December 21, 2017 | February 23, 2023 |
| NCT03317106 | Completed | the Incidence and the Association Between Motor Subtypes and Outcome of Delirium in Ischemic Stroke Patients | August 8, 2017 | August 31, 2018 | |
| NCT03330236 | Completed | N/A | EEG - Guided Anesthetic Care and Postoperative Delirium | October 13, 2017 | September 6, 2019 |
| NCT03349411 | Completed | Spatial Neglect and Delirium After Stroke | July 18, 2017 | December 30, 2020 | |
| NCT03379129 | Completed | Family ICU Delirium Detection Study | November 6, 2017 | September 14, 2018 | |
| NCT03436472 | Completed | N/A | Dexmedetomidine and 5-year Outcome in Elderly Patients After Surgery | June 1, 2017 | April 1, 2019 |
| NCT03470662 | Completed | N/A | Prevention of Delirium Among Elderly Patients With Hip Fractures | March 1, 2017 | September 30, 2017 |
| NCT03471520 | Completed | N/A | Earplugs and Eye Masks for Reducing Delirium | August 6, 2018 | December 8, 2018 |
| NCT03489551 | Completed | Phase 4 | Feasibility of Prophylactic Haldol to Prevent Delirium in Cancer Patients | November 2011 | October 2013 |
| NCT03498560 | Completed | Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium | November 1, 2018 | September 1, 2019 | |
| NCT03528798 | Completed | Analysis of Medication Data With the ApoMining-Database | October 22, 2014 | September 25, 2017 | |
| NCT03541408 | Completed | N/A | Preventative Delirium Protocol in Elderly Patients | May 1, 2016 | April 1, 2021 |
| NCT03550495 | Completed | N/A | A Multidisciplinary Delirium Prevention Strategy Involving Psychiatry in the ICU | April 16, 2018 | June 1, 2019 |
| NCT03553719 | Completed | Enhancing European Management of Analgesia, Sedation and Delirium | October 23, 2018 | May 31, 2020 | |
| NCT03572517 | Completed | N/A | Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position | September 1, 2017 | September 25, 2018 |
| NCT03573479 | Completed | Early Rehabilitation in Critically Ill Children - The PICU Liber8 Study | January 3, 2019 | October 30, 2020 | |
| NCT03588689 | Completed | Phase 4 | Continuous Fascia Iliaca Block for Acute Hip Fractures | May 7, 2018 | May 1, 2019 |
| NCT03604809 | Completed | N/A | Guided Occupational Therapist Cognitive Interventions in Critically Ill Patients | June 15, 2019 | November 30, 2020 |
| NCT03642249 | Completed | N/A | Education for Recognition and Management of Delirium | November 5, 2019 | December 31, 2019 |
| NCT03715244 | Completed | Rate of Postoperative Delirium and Postoperative Cognitive Dysfunction After Spinal Anesthesia | March 12, 2019 | July 14, 2022 | |
| NCT03724201 | Completed | Neuronal Damage In Delirium Study | July 30, 2018 | May 1, 2019 | |
| NCT03729011 | Completed | Phase 4 | Delirium Reduction by Volatile Anesthesia in Cardiac Surgery | January 9, 2019 | January 11, 2024 |
| NCT03773874 | Completed | Assessment of Analgesia, Sedation, Physical Restraints and Delirium in Spanish Intensive Care Units | February 12, 2018 | March 11, 2018 | |
| NCT03776526 | Completed | Researching the Effects of Sleep on STep Count dUring the Postoperative Period | March 1, 2018 | June 30, 2019 | |
| NCT03813459 | Completed | Subsyndromal Delirium in Intensive Care Unit | August 1, 2018 | March 31, 2020 | |
| NCT03832192 | Completed | Phase 2 | Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delirium: a Multi-Site Clinical Study | January 8, 2019 | January 7, 2021 |
| NCT03930719 | Completed | Post-stroke Delirium Screening | April 22, 2019 | August 31, 2019 | |
| NCT03931070 | Completed | Phase 4 | The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU | May 9, 2019 | February 1, 2022 |
| NCT03934645 | Completed | Comparison of Delirium Evaluation Tools Effectiveness in Intensive Care Patients | November 1, 2017 | November 1, 2019 | |
| NCT03944694 | Completed | White Cell Ratios as Markers of Delirium and Outcome in Acute Ischemic Stroke. | June 30, 2015 | March 31, 2019 | |
| NCT03966274 | Completed | DeltaScan Validation Study for the Assessment of Delirium in the ICU and on Wards | February 16, 2019 | February 12, 2021 | |
| NCT03967496 | Completed | Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors | January 1, 2019 | March 31, 2019 | |
| NCT03972384 | Completed | N/A | A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults | January 21, 2022 | March 1, 2023 |
| NCT03980782 | Completed | N/A | The Effect of Music Therapy on Delirium | June 5, 2019 | September 30, 2019 |
| NCT04007523 | Completed | N/A | Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR) | November 21, 2019 | July 27, 2022 |
| NCT04016740 | Completed | Early Phase 1 | The PATHFINDER Study: A Feasibility Trial | August 20, 2019 | July 7, 2020 |
| NCT04041947 | Completed | Delirium Assessment in the Pediatric Intensive Care Unit | November 1, 2018 | December 1, 2019 | |
| NCT04042649 | Completed | N/A | Environmental Intervention on Delirious Patients | June 1, 2013 | October 31, 2014 |
| NCT04046458 | Completed | N/A | De-escalating Vital Sign Checks | March 11, 2019 | November 4, 2019 |
| NCT04068311 | Completed | N/A | Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit | July 1, 2019 | December 30, 2023 |
| NCT04080557 | Completed | Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit Dismissal | November 1, 2018 | February 28, 2019 | |
| NCT04111900 | Completed | N/A | Effect of Sleep on the Recovery of Patients Admitted to the ICU | February 27, 2017 | January 31, 2020 |
| NCT04168268 | Completed | Patient-reported Outcome Measures After Post-anesthesia Care Unit Delirium | November 28, 2017 | December 11, 2018 | |
| NCT04188795 | Completed | N/A | Evaluation of the Effectiveness of Delirium Preventive Care Protocol | May 25, 2018 | April 1, 2019 |
| NCT04189666 | Completed | Phase 1/Phase 2 | Rivastigmine Patch Compared to Melatonin Patch in Prevention of Postoperative Delirium | November 18, 2019 | May 1, 2020 |
| NCT04214106 | Completed | Thiamine Administration and Prevalence of Delirium in the Intensive Care Unit: A Before-after Study | February 19, 2020 | January 1, 2021 | |
| NCT04218461 | Completed | PREdiction of DELIRium in Medical ICU Patients | November 5, 2019 | April 30, 2020 | |
| NCT04219735 | Completed | Phase 2 | Effect of Minocycline on Delirium Incidence in Critically Ill Patients | January 30, 2020 | November 30, 2021 |
| NCT04270331 | Completed | N/A | Assessment and Management of Pain, Agitation, Delirium and Sleep Deprivation (PADS) in ICU by PADS Protocol, Thailand | April 1, 2020 | June 30, 2021 |
| NCT04359914 | Completed | Neurocognitive Impairment in Patients With COVID-19 | April 15, 2020 | December 31, 2023 | |
| NCT04393909 | Completed | N/A | Improving Safety of Diagnosis and Therapy in the Inpatient Setting | July 1, 2019 | December 30, 2021 |
| NCT04401514 | Completed | N/A | Does Rocking Charis Calm Delirious Patients in the Intensive Care Unit | June 1, 2020 | November 13, 2022 |
| NCT04422925 | Completed | s100β, NSE n GFAP in Living Donor Hepatectomy and Delirium | September 1, 2019 | December 1, 2021 | |
| NCT04433416 | Completed | Hypertension and Controlled Hypotension in the Elderly | June 14, 2020 | December 7, 2020 | |
| NCT04467762 | Completed | Neurocognitive Impairment in Pediatric Patients With Meningoencephalitis and Sepsis-associated Encephalopathy | August 3, 2020 | October 31, 2022 | |
| NCT04551508 | Completed | Delirium Screening 3 Methods Study | September 9, 2020 | November 1, 2021 | |
| NCT04571944 | Completed | Phase 3 | Efficacy and Safety of Suvorexant (MK-4305) for Reducing Incidence of Delirium in Japanese Participants at High Risk of Delirium (MK-4305-085) | October 22, 2020 | December 23, 2022 |
| NCT04578886 | Completed | Phase 3 | The Effect of Guanfacine on Delirium in Critically Ill Patients | November 23, 2020 | April 1, 2023 |
| NCT04589767 | Completed | Validation Study of the "CORNELL ASSESSMENT PEDIATRIC DELIRIUM" (CAPD)" Scale in Italian Language | January 1, 2020 | September 30, 2021 | |
| NCT04643834 | Completed | Cerebral Monitoring and Post-operative Delirium and Outcomes | November 21, 2019 | November 30, 2023 | |
| NCT04652622 | Completed | N/A | Use of a Novel Digital Therapeutic Intervention for the Management of Delirium in the Acute Care Environment | March 16, 2021 | December 5, 2022 |
| NCT04737733 | Completed | N/A | Effects of a Dementia-friendly Program | November 22, 2018 | June 16, 2020 |
| NCT04760392 | Completed | N/A | Goal-directed Mobilization of Medical Inpatients | September 13, 2021 | April 18, 2023 |
| NCT04771793 | Completed | Physical Restraint of Critically Ill Patients | September 1, 2021 | March 14, 2023 | |
| NCT04785157 | Completed | Neurotropism and Neuroinflammation in COVID-19 Patients With Delirium. | June 1, 2021 | June 30, 2022 | |
| NCT04816344 | Completed | Emergence Delirium in Children for Magnetic Resonance Imaging | July 1, 2018 | November 1, 2018 | |
| NCT04818827 | Completed | Ketamine Infusion as Sedative Analgesic in Severe ARDS | February 1, 2020 | February 14, 2021 | |
| NCT04846322 | Completed | Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department | March 1, 2021 | August 15, 2022 | |
| NCT04880967 | Completed | Feasibility of an App to Measure Patient Stressors in an Intensive Care Unit (ICU Feel Better App)- a Before-and-after Study | July 4, 2023 | October 11, 2023 | |
| NCT04986488 | Completed | INCIDENCE OF Delirium After Cardiac SURGERY Surgery | July 1, 2018 | December 30, 2018 | |
| NCT05076162 | Completed | Vitamin D Level and Emergence Delirium in Children | February 1, 2019 | February 1, 2021 | |
| NCT05089097 | Completed | Assessment of Postoperative Delirium With CAM ICU Score in Patients Treated With Serotoninergic Reuptake (SSRI) Inhibitors and Undergoing Intervention of Heart Surgery on Pump | June 4, 2020 | September 15, 2021 | |
| NCT05209555 | Completed | Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement) | January 10, 2022 | December 31, 2022 | |
| NCT05218720 | Completed | Delirium and EuroSCORE II in Cardiac Surgery | March 1, 2022 | May 23, 2023 | |
| NCT05236907 | Completed | N/A | The Efficacy of Oral Melatonin in Preventing Postoperative Delirium for Patients Undergoing Orthopedic Surgery Under General Anesthesia | July 1, 2020 | November 1, 2020 |
| NCT05242887 | Completed | Validation of the 3D-CAM and the UB-CAM in French | March 31, 2022 | March 27, 2024 | |
| NCT05273827 | Completed | Effect of Neoadjuvant Anti-PD-1 Immunotherapy on Perioperative Analgesia and Postoperative Delirium | March 22, 2022 | January 2, 2024 | |
| NCT05384964 | Completed | Nurses' Knowledge, Barriers and Practices in the Assessment of Delirium in the Intensive Care Unit | May 1, 2022 | February 28, 2023 | |
| NCT05395559 | Completed | Prevalence and Recognition of Cognitive Impairment in Hospitalized Patients: a Flash Mob Study | September 21, 2022 | September 21, 2022 | |
| NCT05565703 | Completed | N/A | The Use of PARO to Decrease Agitation in Persons With Dementia and/or Delirium | October 30, 2018 | October 30, 2023 |
| NCT05567718 | Completed | The Relationship Between Fasting Time and Delirium | January 1, 2022 | September 1, 2022 | |
| NCT05579093 | Completed | Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia | October 1, 2019 | September 20, 2021 | |
| NCT05656703 | Completed | N/A | Anesthesia Depth Increases Delirium Incidence | September 1, 2015 | March 15, 2021 |
| NCT05732584 | Completed | N/A | Effect of Auditory Stimulation by Family Voices in Preventing Delirium: A Randomized Controlled Trial | March 25, 2023 | November 15, 2023 |
| NCT05793632 | Completed | Phase 2 | Quetiapine in Prevention of Delirium | March 1, 2023 | April 15, 2023 |
| NCT05815550 | Completed | Delirium Related to Proton Pump Inhibitors Use | February 9, 2022 | February 10, 2022 | |
| NCT05932394 | Completed | N/A | Projection of Visual Material on Postoperative Delirium in Patients Undergoing Cardiac Surgery | July 1, 2021 | June 26, 2023 |
| NCT05963958 | Completed | N/A | HD-Tdcs and Pharmacological Intervention For Delirium In Critical Patients With COVID-19 | April 14, 2021 | January 30, 2023 |
| NCT06187389 | Completed | Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium | March 1, 2023 | June 1, 2023 | |
| NCT06334796 | Completed | Early Phase 1 | Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology | October 1, 2023 | January 1, 2024 |
| NCT06339385 | Completed | Management of PADIS in Emergency Intensive Care Unit | June 13, 2021 | August 12, 2021 | |
| NCT06344013 | Completed | The ABCDEF Bundle in Critical Care: a French National Survey Still a Long Way to go! | July 1, 2022 | July 31, 2022 | |
| NCT05431595 | Enrolling by invitation | Phase 2/Phase 3 | Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy | July 19, 2022 | February 2, 2027 |
| NCT06117761 | Enrolling by invitation | N/A | Combined Activity and Cognitive Intervention for ICU Survivors | December 1, 2023 | February 12, 2026 |
| NCT05220761 | Enrolling by invitation | Family Assessment of Pediatric Delirium | August 9, 2021 | June 2024 | |
| NCT04834427 | Enrolling by invitation | Phase 4 | Safety and Efficacy Evaluation of S (+) - Ketamine in Children | April 20, 2022 | December 4, 2024 |
| NCT06232317 | Enrolling by invitation | N/A | Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients | December 9, 2023 | December 31, 2024 |
| NCT06063161 | Enrolling by invitation | N/A | Music Therapy to Prevent Hospital-acquired Delirium in Parkinson's Disease and Dementia With Lewy Bodies | April 1, 2024 | December 1, 2025 |
| NCT06153472 | Not yet recruiting | N/A | Effectiveness of a Virtual Reality-Based Sensory Stimulation Intervention in Preventing Delirium in Intensive Care Units | January 2024 | December 2026 |
| NCT03806413 | Not yet recruiting | Post-surgical Delirium in Patients Undergoing Open Heart Surgery. | October 1, 2024 | December 31, 2024 | |
| NCT06030453 | Not yet recruiting | N/A | Using SMART HOME Strategy to Reduce the Incidence of Delirium in the Intensive Care Unit | January 1, 2024 | December 31, 2024 |
| NCT06460363 | Not yet recruiting | N/A | Transcranial Alternating Current Stimulation on Patients With Delirium and Critical Illness (DeliTACS) | September 1, 2024 | December 31, 2028 |
| NCT06222866 | Not yet recruiting | Anticoagulation and Inflammation Monitoring in Patients After Heart and Vascular Interventions | March 1, 2024 | April 1, 2026 | |
| NCT04575753 | Not yet recruiting | Evaluating the Role of Pre-existing Resolvins in the Resolution of ICU Delirium | October 7, 2023 | May 30, 2024 | |
| NCT06206473 | Not yet recruiting | N/A | Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients | April 1, 2024 | December 1, 2025 |
| NCT06192615 | Not yet recruiting | Phase 3 | Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II) | April 1, 2024 | March 31, 2029 |
| NCT06411561 | Not yet recruiting | N/A | A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors | July 1, 2024 | May 31, 2027 |
| NCT06394778 | Not yet recruiting | Electroencephalogram Characteristics of Surgical Anesthetized Patients and Postoperative. Dilirium | April 22, 2024 | April 15, 2027 | |
| NCT03415061 | Not yet recruiting | N/A | Effect of Intranasal Insulin on POCD and POD | November 1, 2021 | November 30, 2024 |
| NCT06242275 | Not yet recruiting | Perioperative Salivary Alpha-amylase as a Predictor of Delirium After Lower Extremity Vascular Bypass Surgery | February 10, 2024 | July 1, 2024 | |
| NCT05872529 | Not yet recruiting | N/A | Turkish Precision Anaesthesia Study Project | July 2023 | July 2025 |
| NCT01876355 | Not yet recruiting | Phase 3 | The Effect of Clonidine-enhanced Sedation on Delirium in Ventilated Critically Ill Patients | January 2024 | June 2025 |
| NCT06268080 | Not yet recruiting | N/A | Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery | March 31, 2024 | December 31, 2028 |
| NCT05085808 | Not yet recruiting | Phase 4 | RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) | March 1, 2025 | December 1, 2026 |
| NCT06184945 | Not yet recruiting | N/A | Behavioral Economic & Staffing Strategies in the ICU | July 1, 2024 | April 1, 2028 |
| NCT06038136 | Not yet recruiting | N/A | Post-Stroke Enhancement of Delirium Outcomes With Reduction in Neuro-checks | May 1, 2024 | April 1, 2025 |
| NCT05841368 | Not yet recruiting | DELIRIUM SCREENING, INCIDENCE AND MANAGEMENT OBSERVATIONAL STUDY IN 2024 - THE CZECH REPUBLIC | January 1, 2024 | July 31, 2024 | |
| NCT06294158 | Not yet recruiting | Light and Noise: Objectively Assessing Environmental Risk Factors for Delirium in the ICU | April 2024 | November 2025 | |
| NCT06326424 | Not yet recruiting | Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department | April 10, 2024 | March 1, 2025 | |
| NCT03806439 | Not yet recruiting | Post-surgical Delirium in Patients Undergoing Radical Cystectomy. | November 25, 2024 | November 24, 2025 | |
| NCT06240897 | Not yet recruiting | N/A | CURATE.Dtx as a Diagnostic and Management Tool for Delirium | February 2024 | April 2024 |
| NCT06285721 | Not yet recruiting | N/A | Delirium Treatment With Transcranial Electrical Stimulation | February 26, 2024 | March 31, 2027 |
| NCT06403410 | Not yet recruiting | N/A | Delirium Prevention Guideline for Intensive Care Patients | June 15, 2024 | December 15, 2024 |
| NCT06115863 | Not yet recruiting | N/A | Effect of Early Cognitive Stimulation Interventions on Delirium and Cognitive Functions Among Critically Ill Patients | November 2023 | November 2024 |
| NCT05029050 | Recruiting | Phase 4 | Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery | January 17, 2022 | January 2025 |
| NCT05060614 | Recruiting | Analyses of Cerebrospinalfluid in Patients With Delirium | September 1, 2016 | December 30, 2027 | |
| NCT05069428 | Recruiting | Phase 4 | Delirium Reduction With Ramelteon | March 26, 2023 | December 2025 |
| NCT05084482 | Recruiting | External Validation of Delirium Prediction Models for Intensive Care Patients | January 1, 2022 | September 30, 2023 | |
| NCT03124303 | Recruiting | Interventions for Postoperative Delirium: Biomarker-3 | February 13, 2017 | December 2025 | |
| NCT05105906 | Recruiting | Post-operative Delirium (POD) in Patients Undergoing Hip Fracture Surgery | May 1, 2021 | June 30, 2024 | |
| NCT03141619 | Recruiting | Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness-2 | October 13, 2017 | June 2025 | |
| NCT05677646 | Recruiting | Wearable Sensors for Delirium Detection at an Early Stage (WeSen_delirium) | November 23, 2022 | September 30, 2025 | |
| NCT05713877 | Recruiting | Phase 2 | Melatonin for Treatment of Delirium in Critically Ill Adult Patients | February 1, 2023 | November 30, 2024 |
| NCT06071793 | Recruiting | N/A | Family Integration in Therapy Activities in the Intensive Care Unit: The FIT-ICU Feasibility Study | November 30, 2023 | March 21, 2025 |
| NCT04740567 | Recruiting | N/A | Early Cognitive Intervention in Delirium | February 9, 2021 | September 1, 2024 |
| NCT06194474 | Recruiting | Study on Biomarkers of Postoperative Delirium in Elderly Cardiac Surgery Patients | September 5, 2022 | February 2024 | |
| NCT04750395 | Recruiting | Phase 2 | Comparing Haloperidol and Olanzapine in Treating Terminal Delirium | September 1, 2021 | May 2024 |
| NCT04007432 | Recruiting | N/A | Nocturnal Hypoxia in Geriatric Patients After Hip Fracture | November 5, 2020 | November 5, 2025 |
| NCT06076668 | Recruiting | N/A | Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium | October 16, 2023 | October 20, 2024 |
| NCT05786833 | Recruiting | N/A | Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair | March 20, 2023 | October 20, 2023 |
| NCT04792983 | Recruiting | Cognition and the Immunology of Postoperative Outcomes | September 6, 2019 | July 31, 2025 | |
| NCT05801289 | Recruiting | N/A | Quetiapine as Prophylaxis for Delirium in CABG | December 4, 2022 | April 2023 |
| NCT04801589 | Recruiting | Phase 3 | Goal-Directed Sedation in Mechanically Ventilated Infants and Children | May 10, 2021 | January 1, 2027 |
| NCT05811208 | Recruiting | Use of Pupillometry for Pain Assessment in ICU Patients With Delirium | May 1, 2023 | January 1, 2026 | |
| NCT06150339 | Recruiting | N/A | Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibility Study | March 1, 2024 | October 2024 |
| NCT04832568 | Recruiting | Perioperative EEG-Monitoring and Postoperative Delirium in Patients Undergoing Cardiovascular Surgery | June 17, 2021 | December 2023 | |
| NCT05403268 | Recruiting | N/A | The EARLY DELTA Trial | March 2, 2022 | March 2, 2026 |
| NCT06161480 | Recruiting | N/A | Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium | October 6, 2023 | August 29, 2024 |
| NCT05195034 | Recruiting | N/A | Effect of Dexmedetomidine on Postoperative Delirium After Awake Craniotomies | March 31, 2022 | December 31, 2025 |
| NCT02905812 | Recruiting | N/A | Pilot Clinical Trial of an Integrative Intervention to Improve Critically Ill Patients' Delirium and Related Outcomes | March 1, 2019 | May 2024 |
| NCT05834569 | Recruiting | Phase 4 | Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients | June 15, 2023 | December 31, 2025 |
| NCT06172491 | Recruiting | Automating Delirium Severity in the ICU | January 15, 2023 | December 18, 2026 | |
| NCT02945085 | Recruiting | N/A | 3D Team Care for Cognitively Vulnerable Older Adults | March 6, 2017 | July 31, 2024 |
| NCT04081649 | Recruiting | Cerebral Oxygenation and Neurological Functioning After Cardiac Surgery | June 1, 2014 | June 30, 2025 | |
| NCT05127265 | Recruiting | Pervasive Sensing and AI in Intelligent ICU | May 24, 2021 | December 2024 | |
| NCT04937400 | Recruiting | Delirium in Children Undergoing Stem Cell Transplantation | July 12, 2021 | August 2026 | |
| NCT04091724 | Recruiting | Perioperative EEG-Monitoring and Emergence Delirium in Children | December 2, 2019 | January 2025 | |
| NCT04953767 | Recruiting | N/A | The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy | May 12, 2021 | August 31, 2024 |
| NCT04962815 | Recruiting | Ceribell Delirium Data Collection Study | November 10, 2021 | December 31, 2024 | |
| NCT06176144 | Recruiting | N/A | Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients | September 10, 2023 | September 2025 |
| NCT04093219 | Recruiting | Phase 3 | PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients | August 11, 2020 | October 2024 |
| NCT05836714 | Recruiting | Delirium Detection During Routine Patient Care | May 1, 2023 | May 31, 2024 | |
| NCT05114876 | Recruiting | N/A | Redesigning the Surgical Pathway (PROMoTE) | December 13, 2021 | December 2025 |
| NCT05321771 | Recruiting | N/A | Family Caregiver Role in Decreasing Delirium in Older Patients With Fractured Femur Using HELP Principles. | December 2, 2021 | June 30, 2025 |
| NCT05864482 | Recruiting | N/A | Psychosocial Nursing Interventions on Sleep, Anxiety and Delirium in Patients Undergoing Open Heart Surgery | May 9, 2023 | November 30, 2023 |
| NCT05113446 | Recruiting | MDD(Mild Cognitive Impairment Delirium Dementia) Cohort | July 1, 2021 | December 31, 2025 | |
| NCT05373017 | Recruiting | N/A | Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors | February 13, 2023 | January 31, 2028 |
| NCT05891873 | Recruiting | Delirium in the (Neuro)Intensive/Critical Care in the Adult and Paediatric Czech Populations | September 7, 2023 | December 2027 | |
| NCT05384613 | Recruiting | Evaluation of Quality Indicators on Analgesia, Sedation and Delirium in Intensive Care Patients and Their Impact on Outcome Indicators and Economic Indicators | May 12, 2022 | December 31, 2024 | |
| NCT05913531 | Recruiting | Retrospective Evaluation of Delirium Data From Previous Study Patients for Studies at the Clinic for Anesthesiology and Intensive Care Medicine CCM/CVK/CBF | May 23, 2023 | December 31, 2026 | |
| NCT05915377 | Recruiting | Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation | April 3, 2024 | December 2027 | |
| NCT05461092 | Recruiting | Early Phase 1 | Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion | January 1, 2024 | March 31, 2025 |
| NCT05307003 | Recruiting | Trazodone vs. Quetiapine for the Treatment of ICU Delirium | April 1, 2023 | December 2025 | |
| NCT05464355 | Recruiting | Biomarkers Associated With Postoperative Cognitive Dysfunction | January 5, 2023 | November 2029 | |
| NCT05929703 | Recruiting | N/A | Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders | December 4, 2023 | August 2027 |
| NCT05308290 | Recruiting | N/A | Optimizing Cerebral Autoregulation During Surgery | January 9, 2023 | September 12, 2025 |
| NCT04289142 | Recruiting | Phase 4 | Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients | December 1, 2019 | March 2026 |
| NCT05566275 | Recruiting | Remote Cognitive Assessment for Surgical Patients | June 29, 2022 | December 2023 | |
| NCT05972057 | Recruiting | Prediction Model of Long-term Cognitive Dysfunction and Delirium After Cardiac Surgery | August 1, 2023 | July 30, 2025 | |
| NCT04404959 | Recruiting | N/A | Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture | May 10, 2019 | December 31, 2023 |
| NCT05331118 | Recruiting | Perioperative Longitudinal Study of Complications and Long-term Outcomes | February 21, 2020 | February 21, 2040 | |
| NCT05999903 | Recruiting | Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors | September 13, 2023 | December 31, 2024 | |
| NCT05248035 | Recruiting | PupillOmetry for Prediction of DelirIUM | April 15, 2022 | June 2025 | |
| NCT06256354 | Recruiting | N/A | Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival | May 29, 2024 | January 2030 |
| NCT06007755 | Recruiting | Exploring of Serum Biomarkers of Delirium After Cardiovascular Surgery | September 1, 2023 | December 31, 2025 | |
| NCT04456985 | Recruiting | N/A | Effect of Preoperative Intervention With Folic Acid and Vitamin B12 on Postoperative Neurobehavioral Changes in Children | June 1, 2020 | June 30, 2025 |
| NCT06019078 | Recruiting | pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS | January 31, 2024 | January 2026 | |
| NCT05311761 | Recruiting | N/A | CogMe for the Prevention and Early Detection of Delirium | March 1, 2022 | December 31, 2024 |
| NCT05246644 | Recruiting | Phase 3 | IV Acetaminophen After Cardiac Surgery - PILOT | June 6, 2023 | December 15, 2024 |
| NCT03880084 | Recruiting | Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM) | August 1, 2019 | January 1, 2025 | |
| NCT04532606 | Recruiting | Phase 4 | Impact of Remimazolam on Prognosis After Bladder Cancer Surgery | February 5, 2021 | October 2025 |
| NCT06027788 | Recruiting | N/A | CTSN Embolic Protection Trial | September 6, 2023 | April 1, 2027 |
| NCT05623475 | Recruiting | N/A | Effects of Scenario-based Education Initiative and OSCE for Recognition and Management of Delirium | October 25, 2021 | June 30, 2023 |
| NCT06029244 | Recruiting | N/A | Eyecontrol coMmunication Platform for dEliRium manaGemEnt in Intensive Care Units (EMERGE) | March 1, 2024 | May 31, 2025 |
| NCT05640479 | Recruiting | Phase 4 | Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery | December 15, 2022 | May 15, 2023 |
| NCT06036017 | Recruiting | N/A | Care Bundle's Impact on Delirium Prevention in CABG Patients | January 1, 2024 | August 30, 2024 |
| NCT04635774 | Recruiting | Phase 1/Phase 2 | Post Operative Delirium Study | February 25, 2021 | December 31, 2023 |
| NCT05649800 | Recruiting | Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project | March 17, 2023 | August 26, 2026 | |
| NCT04722939 | Recruiting | Neurocognitive Outcomes for ICU Patients With Acute Kidney Injury | January 15, 2021 | January 1, 2027 | |
| NCT03562689 | Suspended | Cognitive Processing in Patients Surviving Delirium. Neuropsychological, EEG and Structural Brain Correlates. | March 1, 2019 | December 2020 | |
| NCT03718156 | Suspended | N/A | The Prevention Program for Alzheimer's Related Delirium (PREPARED) Trial | June 23, 2018 | June 2026 |
| NCT03172897 | Suspended | Phase 4 | Low-dose Dexmedetomidine in Mechanically Ventilated ICU Patients | August 20, 2017 | November 2022 |
| NCT04498585 | Suspended | N/A | Virtual Reality to Reduce Delirium | April 14, 2021 | June 2023 |
| NCT05118867 | Suspended | N/A | Improve the Patients' Recovery With Family- Caregivers to End Delirium | December 16, 2021 | December 2024 |
| NCT03628014 | Terminated | N/A | The Hospital Elder Life Program at the Jewish General Hospital | February 5, 2018 | May 30, 2018 |
| NCT01140529 | Terminated | Phase 3 | Dexmedetomidine for the Treatment of Delirium After Heart Surgery | May 2010 | June 2012 |
| NCT00704301 | Terminated | Phase 4 | Rivastigmine for Intensive Care Unit (ICU) Delirium | November 2008 | May 2010 |
| NCT02604459 | Terminated | N/A | Does Optimized General Anesthesia Care Reduce Postoperative Delirium? | June 1, 2015 | February 28, 2018 |
| NCT01343095 | Terminated | N/A | Direct Noise Reduction in the Intensive Care Units (ICU) Using Earplugs and Noise Canceling Headphones | May 2011 | June 2015 |
| NCT00303433 | Terminated | Phase 4 | Namenda to Prevent Post-Operative Delirium | March 2006 | September 2006 |
| NCT01956604 | Terminated | Phase 2 | The Oslo Study of Clonidine in Elderly Patients With Delirium | April 10, 2014 | September 12, 2017 |
| NCT01966315 | Terminated | The Comparison of Dexmedetomidine and Midazolam for the Sleep in Intensive Care Unit | October 2013 | December 2016 | |
| NCT01139996 | Terminated | Phase 4 | Use of Transdermal Clonidine in Trauma Patients | May 2010 | August 2012 |
| NCT01700816 | Terminated | N/A | Prevention of Delirium After Bone Marrow Transplantation | October 2012 | October 2013 |
| NCT00826553 | Terminated | Phase 1 | How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units | January 2009 | December 2013 |
| NCT02689388 | Terminated | N/A | Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery. | August 28, 2016 | December 31, 2018 |
| NCT03682874 | Terminated | Identifying Novel Aging Targets for Treatment of Delirium | October 10, 2018 | February 20, 2020 | |
| NCT02818764 | Terminated | Delirium, Intraoperative Cerebral Perfusion and EEG Abnormalities After Total Hip Arthroplasty | June 2016 | December 2020 | |
| NCT02807467 | Terminated | Phase 4 | Influence of Dexmedetomidine or Propofol on ICU Delirium | March 1, 2019 | February 11, 2023 |
| NCT04246892 | Terminated | Impact of Alarm Reduction on Delirium in ICU | February 3, 2020 | February 23, 2023 | |
| NCT00460473 | Terminated | Phase 3 | A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Hip Fracture Repair Surgery | April 2007 | November 2007 |
| NCT02056171 | Terminated | Phase 1/Phase 2 | Efficacy of Quetiapine for Pediatric Delirium | March 2015 | December 2016 |
| NCT00300391 | Terminated | Phase 3 | ORIC-I: Optimizing Recovery From Intensive Care: Mechanical Ventilation and Delirium | March 2006 | October 2011 |
| NCT02588742 | Terminated | N/A | The Effect of Melatonin on Postoperative Delirium in Elderly ICU Patients | February 2, 2015 | January 15, 2016 |
| NCT02654314 | Terminated | Phase 3 | Prevention of Delirium in Inpatients Utilizing Melatonin | July 2016 | November 3, 2017 |
| NCT03735927 | Terminated | N/A | Clinical Evaluation Program of DeltaScan (Ward) | January 1, 2019 | June 29, 2021 |
| NCT03735940 | Terminated | N/A | Clinical Evaluation Program of DeltaScan (ICU) | March 1, 2019 | June 29, 2021 |
| NCT00833300 | Terminated | N/A | Haloperidol vs Olanzapine for the Management of ICU Delirium | June 2008 | November 2011 |
| NCT02109081 | Terminated | Phase 4 | Dexamethasone and Postoperative Delirium | April 2014 | February 2021 |
| NCT00286936 | Terminated | Phase 4 | Incidence of Delirium in Hip Fracture Patients Randomized to Regular Hypnotics vs Placebo | February 2004 | January 2007 |
| NCT03342989 | Terminated | N/A | Speed of Processing Training for Cognitive Deficits After Delirium in Older Adults | August 13, 2018 | May 31, 2020 |
| NCT00599287 | Terminated | Phase 3 | Methylphenidate, Rivastigmine or Haloperidol in Hypoactive Delirium in Intensive Care Patients | February 2008 | May 2008 |
| NCT03337282 | Terminated | Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients | September 21, 2017 | September 30, 2021 | |
| NCT00954603 | Terminated | Phase 3 | A Double-blind, Randomized, Controlled Trial of Quetiapine Versus Haloperidol for the Treatment of Delirium | June 2009 | July 2012 |
| NCT00622011 | Terminated | Phase 4 | Risperidone and Zotepine in the Treatment of Delirium | January 2008 | March 2009 |
| NCT01698125 | Terminated | Autonomic Cardiovascular Control for Elderly Surgery Patients | October 2012 | November 2012 | |
| NCT04841122 | Terminated | N/A | Improved Patient Safety for Acute Restless Medical Patients With Supplemental Observation | April 19, 2021 | September 30, 2021 |
| NCT03200600 | Terminated | Phase 4 | Dexamethasone, Flurbiprofen Axetil and Delirium After Lung Cancer Surgery | August 2, 2017 | December 26, 2018 |
| NCT03628391 | Terminated | Phase 3 | Haloperidol for Delirium in Adult Critically Ill Patients | February 22, 2018 | January 23, 2021 |
| NCT00961389 | Unknown status | Validating a Delirium Prediction Model for Critically Ill Patients | May 2009 | October 2009 | |
| NCT05325827 | Unknown status | N/A | Effect of Ultrasound-guided H-FICB in Patients Undergoing Arthroscopic Knee Surgery | February 5, 2022 | February 5, 2023 |
| NCT05356078 | Unknown status | Association Between Prescription of Antidepressants and Delirium in the Elderly : Analysis From the World Health Organization Global Database | January 3, 2022 | June 3, 2022 | |
| NCT03569358 | Unknown status | N/A | Immersive Virtual Reality in Mechanically Ventilated Patients | July 2, 2018 | July 2, 2019 |
| NCT05442892 | Unknown status | N/A | Use of Near Infrared Spectroscopy (NIRS) as a Biomarker of Delirium in Hospitalized Older Adults Doing Physical Exercise | February 7, 2022 | February 27, 2023 |
| NCT03647436 | Unknown status | Incidence of Geriatric Syndromes Overlap | August 1, 2018 | December 31, 2019 | |
| NCT03655847 | Unknown status | Phase 4 | Acceptable Hemodynamic Changes in Dexmedetomidine for Single Intravenous Bolus Injection | May 23, 2018 | April 23, 2020 |
| NCT05525702 | Unknown status | N/A | VR Interventions to Reduce the Prevalence of Delirium in ICU Patients | April 18, 2022 | April 17, 2024 |
| NCT03807388 | Unknown status | N/A | ReMindCare App for Patients From First Episode of Psychosis Unit. | September 2019 | September 2023 |
| NCT03860714 | Unknown status | Correlation Between Urine UACR and Postoperative Neurocognitive Disorder in Elderly Patients With Non-cardiac Surgery | January 1, 2019 | May 30, 2020 | |
| NCT03949114 | Unknown status | N/A | Rehabilitation Intervention on Prevention of Postoperative Delirium | May 1, 2019 | October 31, 2021 |
| NCT04005196 | Unknown status | EEG Phase Synchrony, Sedation and Delirium in the CVICU | September 1, 2019 | June 1, 2020 | |
| NCT04078503 | Unknown status | Neuroinflammation During ICU-associated Delirium in Critically Ill Patients and Its Association With Structural and Functional Brain Alterations: a Nested Case-control Study | March 25, 2019 | June 25, 2021 | |
| NCT04084821 | Unknown status | Estimation of Delirium Data Completeness | October 2019 | November 2020 | |
| NCT04127500 | Unknown status | N/A | The Mechanism of Dexmedetomidine in Improving Delirium After Cardiac Surgery | August 1, 2019 | August 31, 2020 |
| NCT04151914 | Unknown status | Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary Bypass: a Prospective Observational Study | November 1, 2019 | August 2020 | |
| NCT01838733 | Unknown status | Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery | April 2014 | ||
| NCT04168515 | Unknown status | Lived Experiences and Impact of Delirium in Critically Ill Children: a Qualitative Study | September 10, 2019 | December 2021 | |
| NCT01952899 | Unknown status | The ICU DElirium in Clinical PracTice Implementation Evaluation Study Screening and Treatment | April 2012 | April 2016 | |
| NCT04216615 | Unknown status | Effect of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Orthopaedic Surgery. | January 4, 2020 | October 1, 2020 | |
| NCT02004665 | Unknown status | Incidence and Prognostic Value of DELIRIUM in Patients With Acute CORonary synDrome: an observatIonal Study | December 2013 | November 2016 | |
| NCT02025855 | Unknown status | Phase 4 | Adjunct Methadone to Decrease the Duration of Mechanical Ventilation in the Medical Intensive Care Unit | January 2014 | March 2015 |
| NCT04227873 | Unknown status | Sleep and Cognition After Ambulatory Hip and Knee Arthroplasty | March 2020 | July 2020 | |
| NCT00611377 | Unknown status | Study on the Incidence of Delirium in a Respiratory Weaning Centre | January 2007 | March 2008 | |
| NCT02078583 | Unknown status | Phase 4 | The Effect of Analgesia Based Sedation Protocol on Brain Function of Critical Care Patients | July 2014 | |
| NCT02080169 | Unknown status | Phase 4 | Safety and Efficacy of Combined Sedation With Midazolam and Dexmedetomidine in ICU Patients | February 2014 | December 2014 |
| NCT04312893 | Unknown status | N/A | The Effectiveness of Acupuncture for Delirium in Critically Ill Patients | March 12, 2020 | May 30, 2022 |
| NCT04320082 | Unknown status | Alteration of Blood-Brain-Barrier Permeability at Loss of Consciousness in Delirious Patients Recorded With Direct-Current Electroencephalography (ACDC) | August 10, 2020 | June 15, 2022 | |
| NCT02108795 | Unknown status | N/A | The Effect of Remifentanil Infusion During Emergence on the Incidence of Emergence Delirium | April 2014 | May 2016 |
| NCT02117726 | Unknown status | Phase 4 | Impact of Various Sedation Regimens on the Incidence of Delirium | May 2014 | |
| NCT02119078 | Unknown status | N/A | Acute Care for Elders (ACE) Program at OHSU Hospital | January 2014 | December 20, 2020 |
| NCT02241655 | Unknown status | N/A | Electroencephalography Guidance of Anesthesia | January 2015 | October 2020 |
| NCT02258386 | Unknown status | Assessment of Delirium in Hospitalized Patients | October 2014 | September 2017 | |
| NCT04406350 | Unknown status | N/A | Tight End-tidal Gas Control During Anesthesia to Decrease Postoperative Delirium Anesthetic Management | June 15, 2020 | December 31, 2021 |
| NCT02297763 | Unknown status | Phase 3 | Prophylactic Quetiapine on Delirium Prevention in Critically Ill Patients | March 2015 | |
| NCT01650896 | Unknown status | N/A | Prospective Randomised Controlled Trial of Delirium Management by Geriatric Medicine Versus General Medicine | July 2012 | July 2016 |
| NCT02305589 | Unknown status | The Clinical Changes Before and After Sugammadex in the Patients Undergoing Hip Surgery on the Aspect of Delirium | September 2014 | November 2016 | |
| NCT04505059 | Unknown status | N/A | Different Anesthetic Strategies on Postoperative Cognitive Function and Delirium in Patients Undergoing Cardiac Surgery | September 11, 2020 | January 18, 2023 |
| NCT04527341 | Unknown status | Postoperative Delirium in Cardiac Surgery ICU | January 1, 2021 | September 30, 2022 | |
| NCT04538469 | Unknown status | Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff | September 2020 | December 2021 | |
| NCT04544085 | Unknown status | N/A | A Study on Noise Exposure Status and the Effect of Noise Management in Pediatric Intensive Care Unit | July 16, 2020 | December 2020 |
| NCT04556227 | Unknown status | N/A | Simultaneous Recumbent Cycling and Cognitive Training | January 2021 | December 1, 2022 |
| NCT01623297 | Unknown status | Confusion in the Elderly After Colon Surgery | January 2012 | January 2015 | |
| NCT02528513 | Unknown status | Phase 4 | Midazolam Used Alone or Sequential Use of Midazolam and Propofol/Dexmedetomidine in Mechanically Ventilated Patients | December 2015 | February 2017 |
| NCT04589169 | Unknown status | Non-Invasive Eye Tracking for the Diagnosis of Delirium on ICU | December 7, 2020 | October 12, 2021 | |
| NCT04643548 | Unknown status | WHO Covid 19 - Neurological Abnormalities in SARS-CoV-2 ICU Patients | October 13, 2020 | August 13, 2021 | |
| NCT04649450 | Unknown status | N/A | MusiC to Prevent deliriUm During neuroSurgerY | July 9, 2020 | March 9, 2023 |
| NCT02564939 | Unknown status | Phase 4 | Ramelteon Prevention of Delirium - RCT | February 23, 2017 | June 2019 |
| NCT04733703 | Unknown status | Impact of Postanesthesia Care Unit Delirium on Postoperative Quality of Recovery | October 2021 | August 2022 | |
| NCT02591589 | Unknown status | N/A | Intraoperative Oxygen Concentration and Neurocognition After Cardiac Surgery | July 2015 | March 1, 2021 |
| NCT04758936 | Unknown status | Phase 4 | Clonidine vs. Dexmedetomidine in Agitated Delirium in Intensive Care Patients | February 1, 2021 | February 28, 2023 |
| NCT02615340 | Unknown status | Phase 2 | Melatonin for Prevention of Delirium in Critically Ill Patients | October 12, 2017 | October 12, 2019 |
| NCT02637882 | Unknown status | Phase 2 | The Effect of Applying Multidisciplinary Bundle Intervention on the Delirium Incidence in Critically Ill Patients | December 2015 | December 2016 |
| NCT02644980 | Unknown status | Phase 4 | Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery | December 2015 | August 2016 |
| NCT02691013 | Unknown status | N/A | The Impact of Ramelteon on Sleep and Delirium in Patients Who Undergo Pulmonary Thromboendarterectomy (PTE) Surgery | February 2016 | December 1, 2022 |
| NCT02699801 | Unknown status | N/A | Dexmedetomidine Use in ICU Sedation and Postoperative Recovery in Elderly Patients and Post-cardiac Surgery | January 2016 | February 2018 |
| NCT02707016 | Unknown status | N/A | Different Doses of Sevoflurane During Induction of Anesthesia on Emergence Delirium in Children | December 2015 | December 2016 |
| NCT04812041 | Unknown status | Relationship Between Delirium Severity by CAM-ICU 7 and 4C Mortality Score of the COVID-19 Patients in ICU | January 21, 2021 | May 25, 2021 | |
| NCT02782429 | Unknown status | Phase 4 | The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery | April 2016 | |
| NCT02801851 | Unknown status | N/A | Delirium Screening of the Elderly in the Emergency Department | July 2015 | June 2017 |
| NCT04846023 | Unknown status | N/A | Pediatric Delirium Screening in the PICU Via EEG | September 2021 | September 2023 |
| NCT02892968 | Unknown status | N/A | ED Ultrasonographic Regional Anesthesia to Prevent Incident Delirium in Hip Fracture Patients | September 2016 | December 2021 |
| NCT04853706 | Unknown status | N/A | Validation of the 3D-CAM Turkish Version | April 18, 2021 | December 18, 2021 |
| NCT04876937 | Unknown status | N/A | Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients | May 28, 2021 | April 2024 |
| NCT02948374 | Unknown status | Biomarkers in Cerebrospinal Fluid in Critical Care Patients With Delirium | October 2016 | December 2018 | |
| NCT04920734 | Unknown status | Description of Therapy Options and Successes in the Long-term Course of Delirium in the Recovery Room - CESARO II | October 1, 2021 | June 2023 | |
| NCT04950738 | Unknown status | N/A | The Effectiveness of Acupuncture for Complications in Critically Ill Patients | August 1, 2021 | September 30, 2022 |
| NCT03013790 | Unknown status | Phase 4 | Melatonin Use in the Intensive Care Elderly Population | December 2016 | January 2018 |
| NCT01343433 | Unknown status | Influence of Light Therapy on Confusion in Patients at the Intensive Care Unit | March 2011 | May 2011 | |
| NCT05000476 | Unknown status | N/A | Using Eye Mask and Earplugs on Prevention of Delirium | February 21, 2020 | September 21, 2021 |
| NCT05055895 | Unknown status | Association of Anticholinergic Burden With Onset of Delirium in Older Adults With Alzheimer Dementia: | January 1, 2005 | December 2022 | |
| NCT05082623 | Unknown status | N/A | The Effect of Music on Delirium, Pain, Need of Sedation, Anxiety and Vital Parameters | September 14, 2020 | October 2021 |
| NCT05108207 | Unknown status | N/A | A Software to Prevent Delirium (PREVEDEL) in Hospitalized Older Adults | August 1, 2021 | January 15, 2023 |
| NCT01267630 | Unknown status | The Validity of the Thai Version of the Confusion Assessment Method | January 2011 | November 2011 | |
| NCT03149783 | Unknown status | Phase 2 | Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores | February 13, 2018 | October 31, 2021 |
| NCT03158909 | Unknown status | N/A | Trial of a Non-pharmacological Intervention to Prevent Delirium Among Elderly In-patients | January 15, 2020 | July 30, 2020 |
| NCT03165539 | Unknown status | Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients | September 2015 | February 2019 | |
| NCT03199950 | Unknown status | Phase 4 | PROfylactic Haloperidol in Patients Defined as High Risk for DElirium With Delirium Risk mOdel | June 23, 2017 | November 23, 2018 |
| NCT03218358 | Unknown status | Effect of the Intra-abdominal Pressure on the Risk of Delirium in Mechanically Ventilated Patients. | July 1, 2016 | October 1, 2020 | |
| NCT05172583 | Unknown status | N/A | Nursing Intervention to Reduce Incidence and Duration of Delirium in Patients in Intensive Care | July 5, 2021 | March 31, 2022 |
| NCT05178680 | Unknown status | N/A | Combination of Music and Relaxing Light on the Patient's Anxiety After Cardiac Surgery in the Intensive Care Unit | May 13, 2022 | June 2023 |
| NCT03256500 | Unknown status | N/A | Transcranial Direct Current Stimulation for the Treatment of Delirium | September 2016 | June 30, 2020 |
| NCT03323619 | Unknown status | Impact of Anesthesia Technique on Post-operative Delirium After Transcatheter Aortic Valve Implantation | November 2, 2017 | November 2, 2020 | |
| NCT03324867 | Unknown status | N/A | The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery. | April 2022 | April 2023 |
| NCT03351985 | Unknown status | The Study of Post-operation Delirium and Prognosis of Cardiac Surgery Patients | December 1, 2017 | August 31, 2018 | |
| NCT03355053 | Unknown status | Phase 2 | Investigation of Sleep in the Intensive Care Unit | June 1, 2018 | April 1, 2023 |
| NCT03423875 | Unknown status | N/A | Predicting Emergency Department Delirium With an Interactive Customizable Tablet to Prevent Repeat Visits | March 1, 2018 | March 2020 |
| NCT02903901 | Withdrawn | Phase 4 | Melatonin for Prevention of Post- Operative Delirium Pilot Study Protocol | June 2015 | June 2018 |
| NCT02856737 | Withdrawn | N/A | Reducing Delirium in the Surgical Intensive Care Unit | August 2016 | July 2017 |
| NCT02840591 | Withdrawn | Phase 4 | Ramelteon and Citicoline for Delirium | July 2016 | November 2017 |
| NCT02673450 | Withdrawn | PER3 Clock Gene Polymorphism, Clock Gene Expression and Delirium in the Intensive Care Unit. | September 2018 | September 2020 | |
| NCT00464763 | Withdrawn | Phase 3 | A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Heart Surgery | April 2007 | September 2007 |
| NCT03293927 | Withdrawn | Phase 2 | Polypharmacy-related Adverse Events in Critically Ill Children | April 9, 2018 | July 1, 2019 |
| NCT02394418 | Withdrawn | Phase 4 | Effect of Sevoflurane, Propofol and Dexmedetomidine on Delirium & Neuroinflammation in Mechanically Ventilated Patients | September 1, 2017 | August 2018 |
| NCT02366299 | Withdrawn | Phase 4 | Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS. | February 2015 | December 2018 |
| NCT02282241 | Withdrawn | Phase 4 | Melatonin for Delirium Prophylaxis | February 2016 | September 2021 |
| NCT03518996 | Withdrawn | N/A | Non-Invasive Brain Stimulation and Delirium | September 1, 2018 | December 1, 2022 |
| NCT03732443 | Withdrawn | FAM-CAM Translation and Validation Into German | January 1, 2019 | March 31, 2019 | |
| NCT04382170 | Withdrawn | Phase 2 | Dexmedetomidine Sublingual Film for the Management of Agitation in Delirium: Safety and Preliminary Efficacy | June 2020 | June 2021 |
| NCT02119806 | Withdrawn | Phase 4 | Decreasing the Incidence of Delirium After Cardiac Surgery | August 2017 | August 2017 |
| NCT02118688 | Withdrawn | Phase 4 | Efficacy and Safety of Risperidone and Trazodone Monotherapy and Combination Therapy in Critically Ill Patients With Delirium | March 2011 | March 2016 |
| NCT04249141 | Withdrawn | Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts | January 28, 2020 | July 31, 2023 | |
| NCT03572257 | Withdrawn | Phase 2/Phase 3 | Quetiapine Treatment for Pediatric Delirium | April 15, 2019 | March 2, 2020 |
| NCT05313386 | Withdrawn | Phase 2 | Study of BXCL501 In Agitation Associated With Delirium in ICU Patients | February 23, 2021 | February 21, 2022 |
| NCT01162369 | Withdrawn | Brief Delirium Assessments in Non-Intensive Care Unit (ICU) Patients | July 2013 | July 2016 | |
| NCT05003102 | Withdrawn | Phase 4 | Dexmedetomidine Cycling and Sleep in the Pediatric ICU | February 20, 2023 | June 30, 2023 |
| NCT01353378 | Withdrawn | Phase 4 | Use of Dexmedetomidine in Children Undergoing Oral Maxillofacial Surgery to Decrease Emergence Delirium | June 2011 | December 2011 |
| NCT03360474 | Withdrawn | N/A | Implementation of a Delirium Screening | June 2018 | December 2018 |
| NCT04954261 | Withdrawn | Delirium Detection in Pediatric Intensive Care Unit Through a French Translation of the CAPD : a French Monocentric Observational Study | December 6, 2018 | December 6, 2018 | |
| NCT02028260 | Withdrawn | Phase 3 | Modafinil Versus Placebo for Hypoactive Delirium in the Critically Ill | January 2014 | October 2015 |
| NCT04881097 | Withdrawn | Cognitive Function and Health-related Quality of Life After Neuro-intensive Care | August 1, 2021 | August 1, 2025 | |
| NCT01727375 | Withdrawn | N/A | Prevention of Delirium With Light in the Intensive Care Unit | July 2013 | November 2016 |
| NCT01687751 | Withdrawn | Phase 2 | Pilot Study Comparing Treatment With Dexmedetomidine to Midazolam for Symptom Control in Advanced Cancer Patients | November 2012 | November 2014 |
| NCT00786318 | Withdrawn | Phase 4 | Ziprasidone vs Standard Therapy for Agitated Patients in the ED | September 2008 | July 2011 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0031258
- MeSH unique ID (MeSH (Medical Subject Headings))
- D003693