Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL10 MUTATION
IL10 MUTATION - Associated Disease
- IMMUNE SUPPRESSION
- Source Database
- DisGeNET
- Description
- The combination of oral delivery of bioencapsulated FIX and intravenous replacement therapy induced a complex, interleukin-10 (IL-10)-dependent, antigen-specific systemic immune suppression of pathogenic antibody formation (immunoglobulin [Ig] 1/inhibitors, IgE) in hemophilia B mice.
- Pubmed
- 25700434
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
Drugs