Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL10 MUTATION
IL10 MUTATION - Associated Disease
- chronic lymphocytic leukemia
- Source Database
- DisGeNET
- Description
- IPI-145 potently inhibits the CD40L/IL-2/IL-10 induced proliferation of CLL cells with an IC50 in sub-nanomolar range.
- Pubmed
- 25917267
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0127254303793718
Drugs