Ovarian Serous Adenocarcinoma

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Information
Disease name
Ovarian Serous Adenocarcinoma
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02953457 Active, not recruiting Phase 2 Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer With BRCA1 or BRCA2 Mutation June 29, 2017 October 15, 2024
NCT00565851 Active, not recruiting Phase 3 Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer December 6, 2007 January 1, 2028
NCT05451849 Active, not recruiting Phase 1/Phase 2 A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer June 21, 2022 October 30, 2028
NCT01116648 Active, not recruiting Phase 1/Phase 2 Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer April 14, 2010 February 13, 2025
NCT01167712 Active, not recruiting Phase 3 Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer September 27, 2010 June 7, 2024
NCT02020707 Active, not recruiting Phase 1 Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers February 24, 2014 June 30, 2025
NCT02068794 Active, not recruiting Phase 1/Phase 2 MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer March 31, 2014 December 31, 2024
NCT02101788 Active, not recruiting Phase 2/Phase 3 Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer February 27, 2014 October 11, 2024
NCT02364713 Active, not recruiting Phase 2 MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer March 13, 2015 February 28, 2028
NCT02502266 Active, not recruiting Phase 2/Phase 3 Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer May 3, 2016 June 30, 2024
NCT04498117 Active, not recruiting Phase 3 Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery August 25, 2020 August 26, 2027
NCT01504126 Completed Early Phase 1 Propranolol Hydrochloride and Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer March 9, 2012 August 15, 2019
NCT00262847 Completed Phase 3 Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer September 2005 April 2015
NCT02016833 Completed Development of Immunological Assays for the Evaluation of Tumor Antigen Specific Immunity October 2013 December 2014
NCT02179970 Completed Phase 1 To Assess the Safety of Continuous IV Administration of Plerixafor in Patients With Advanced Pancreatic, Ovarian and Colorectal Cancers June 2015 December 14, 2018
NCT00888615 Completed Phase 2 Elesclomol Sodium and Paclitaxel in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer December 13, 2010 August 31, 2016
NCT00951496 Completed Phase 3 Bevacizumab and Intravenous or Intraperitoneal Chemotherapy in Treating Patients With Stage II-III Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer August 11, 2009 January 11, 2016
NCT00989651 Completed Phase 1 Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer October 28, 2009 April 10, 2020
NCT01074411 Completed Phase 1 Intraperitoneal Bortezomib and Carboplatin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer April 5, 2010 January 27, 2018
NCT01097746 Completed Phase 2 First-Line Treatment of Bevacizumab, Carboplatin, and Paclitaxel in Treating Participants With Stage III-IV Ovarian, Primary Peritoneal, and Fallopian Tube Cancer April 14, 2010 September 13, 2022
NCT05074472 Completed Phase 1/Phase 2 A Phase 1/2, First-in-Human, Open Label, Dose Escalation Study Of A CSP Targeting Functional Antibody in Solid Tumors January 14, 2022 September 30, 2023
NCT02853318 Completed Phase 2 Pembrolizumab, Bevacizumab, and Cyclophosphamide in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer September 1, 2016 June 30, 2021
NCT05605535 Recruiting Phase 2 Oregovomab Plus Chemotherapy in Neo-adjuvant Setting in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer February 7, 2023 May 15, 2026
NCT04575935 Recruiting Phase 3 Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial August 5, 2020 December 31, 2028
NCT04919629 Recruiting Phase 2 APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion February 17, 2023 December 1, 2025
NCT05001282 Recruiting Phase 1/Phase 2 A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα) September 13, 2021 June 15, 2025
NCT05415709 Recruiting Early Phase 1 Hyperthermic Intraperitoneal Chemotherapy With Cisplatin During Surgery or Cisplatin Before Surgery for the Treatment of Stage III or IV Ovarian, Fallopian Tube or Peritoneal Cancer June 13, 2022 December 31, 2024
NCT03641287 Terminated N/A The Effects of Exercise on Distress, Quality of Life, and Biomarkers in Ovarian Cancer Survivors December 5, 2018 September 30, 2022
NCT02923739 Terminated Phase 2 Paclitaxel and Bevacizumab With or Without Emactuzumab in Treating Patients With Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer May 5, 2017 September 27, 2022
NCT00108745 Unknown status Phase 3 Paclitaxel, Polyglutamate Paclitaxel, or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Peritoneal Cancer, or Fallopian Tube Cancer March 21, 2005 February 22, 2022
NCT00719303 Unknown status Phase 3 Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer June 18, 2012
NCT03648489 Unknown status Phase 2 Dual mTorc Inhibition in advanCed/Recurrent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (of Clear Cell, Endometrioid and High Grade Serous Type, and Carcinosarcoma) September 21, 2018 December 2022
NCT02627430 Withdrawn Phase 1 Talazoparib and HSP90 Inhibitor AT13387 in Treating Patients With Metastatic Advanced Solid Tumor or Recurrent Ovarian, Fallopian Tube, Primary Peritoneal, or Triple Negative Breast Cancer March 2016