ovarian carcinoma (Cancer)

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Information
Disease name
ovarian carcinoma
Disease ID
DOID:4001
Description
"An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary." [url:https\://www.cancer.gov/types/ovarian]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02194387 Active, not recruiting N/A Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members September 17, 2014 September 30, 2025
NCT04917744 Active, not recruiting Metabolite Levels in Ovarian Cancer Patients Receiving Maintenance PARP Inhibitors April 1, 2021 March 19, 2025
NCT03839524 Active, not recruiting Phase 1 A Trial Evaluating TG4050 in Ovarian Carcinoma. December 9, 2019 December 2025
NCT05194735 Active, not recruiting Phase 1/Phase 2 Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors April 4, 2022 November 30, 2024
NCT01696994 Active, not recruiting N/A Screening for Ovarian Cancer in Older Patients (PLCO Screening Trial) November 16, 1993 March 11, 2025
NCT02345265 Active, not recruiting Phase 2 Testing the Combination of the Study Drugs Cediranib and Olaparib in Recurrent Ovarian Cancer May 23, 2016 August 9, 2024
NCT01366144 Active, not recruiting Phase 1 Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction June 20, 2011 March 5, 2025
NCT02419495 Active, not recruiting Phase 1 Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies June 26, 2015 December 31, 2024
NCT02465060 Active, not recruiting Phase 2 Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) August 17, 2015 December 31, 2025
NCT02487693 Active, not recruiting Phase 2 Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for the Patients With Ovarian Carcinoma July 2015 June 2040
NCT03748186 Active, not recruiting Phase 1 Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers February 1, 2019 November 2024
NCT01907789 Active, not recruiting N/A Prophylactic Salpingectomy With Delayed Oophorectomy August 26, 2013 December 31, 2030
NCT04310826 Active, not recruiting N/A Dietary Magnesium in Preventing Low Blood Magnesium Levels in Patients With Ovarian Cancer Receiving Carboplatin Chemotherapy April 23, 2019 April 1, 2024
NCT02584478 Active, not recruiting Phase 3 Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002) December 2015 December 2024
NCT05446870 Active, not recruiting Phase 2 Pembrolizumab With Chemotherapy and MK-4830 for Treating Participants With Ovarian Cancer (MK-4830-002) July 25, 2022 December 26, 2024
NCT04257045 Active, not recruiting Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their Relatives August 21, 2019 April 30, 2024
NCT03965481 Active, not recruiting N/A PET/MR Versus CECT Scans in Imaging Patients With Ovarian Cancer or Highly Suspected Ovarian Cancer May 12, 2018 April 30, 2025
NCT02124421 Active, not recruiting Phase 2 HOT: HIPEC in Ovarian Cancer as Initial Treatment April 2014 April 2028
NCT05200364 Active, not recruiting Phase 1 A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer March 22, 2022 January 2026
NCT04905082 Active, not recruiting N/A HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics December 30, 2021 June 30, 2024
NCT04902144 Completed N/A Clinical Outcomes for Offering Genetic Testing in a Tiered Approach August 3, 2020 December 31, 2021
NCT01481701 Completed Phase 2 A Trial Evaluating Efficacy and Safety of Oxaliplatin With 5-Fluorouracil in Patients With Recurrent Ovarian Carcinoma October 2008 May 2014
NCT01519869 Completed Phase 2 Trial of Chemotherapy in Ovarian, Fallopian Tube and Peritoneal Carcinoma March 2012 October 11, 2019
NCT01657747 Completed N/A Whole-body Diffusion MRI for Staging, Response Prediction and Detecting Tumor Recurrence in Patients With Ovarian Cancer November 2011 March 2015
NCT01689714 Completed Phase 2 Safety and Efficacy of Folatescan (Technetium TC 99M EC20) in Patients With Suspected Ovarian Carcinoma or Recurrent Endometrial Carcinoma August 2003 August 2005
NCT01709487 Completed Phase 1/Phase 2 Feasibility Study of HIPEC for Patients With Stage III or Only Pleural Stage IV Ovarian Carcinoma in First Line Therapy May 2010 October 2015
NCT02025985 Completed Phase 2 Study of KPT-330 (Selinexor) in Female Patients With Advanced Gynaecologic Malignancies April 9, 2014 March 29, 2017
NCT02159989 Completed Phase 1 Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery June 18, 2014 January 29, 2024
NCT02166905 Completed Phase 1/Phase 2 DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, and IDO1 Inhibitor INCB024360 in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission October 10, 2014 August 20, 2020
NCT03857087 Completed 68Ga-PSMA PET in Diagnosing Metastasis in Patients With Ovarian Cancer April 2, 2018 June 30, 2022
NCT02297958 Completed Impact of Fas/FasL in Chemotherapy Response in Epithelial Ovarian Carcinoma January 15, 2015 July 27, 2019
NCT02315469 Completed Comprehensive Patient Questionnaires in Predicting Complications in Older Patients With Gynecologic Cancer Undergoing Surgery February 10, 2015 February 9, 2019
NCT03756818 Completed Phase 1 TAK-659 and Paclitaxel in Treating Patients With Advanced Solid Tumors March 5, 2019 February 23, 2023
NCT02578888 Completed N/A Palliative Care in Improving Quality of Life in Patients With High Risk Primary or Recurrent Gynecologic Malignancies April 2015 April 2019
NCT02584465 Completed Phase 2 REGorafenib vsTamoxifen in Patients With Platinum-sensitive OVARian Carcinoma and Isolated Biological Progression August 28, 2015 September 19, 2021
NCT02595281 Completed N/A HE4 as a Relapse Biomarker in Ovarian Cancers April 1, 2016 July 18, 2022
NCT03562533 Completed Real-World Effectiveness of PLD in Platinum- Sensitive Recurrent Ovarian Cancer May 17, 2018 December 17, 2018
NCT03517488 Completed Phase 1 A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors July 10, 2018 September 6, 2022
NCT03027479 Completed N/A Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss March 1, 2017 July 16, 2019
NCT03379376 Completed N/A EHealth Mindful Movement and Breathing in Improving Outcomes in Participants Undergoing Gynecologic Surgery April 5, 2018 November 2, 2018
NCT03372720 Completed N/A Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors May 11, 2018 April 12, 2022
NCT03085225 Completed Phase 1 Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas. May 5, 2017 January 4, 2022
NCT03180294 Completed Phase 2 Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer May 31, 2017 February 22, 2021
NCT00181701 Completed Phase 2 Intraperitoneal Paclitaxel and Carboplatin in the Treatment of Women With Carcinoma of Mullerian Origin October 2004 May 2006
NCT00183794 Completed Phase 2 Clinical Trial of Docetaxel in Combination With Gemcitabine in Platinum-Resistant Ovarian Cancer and Primary Peritoneal Carcinoma November 2002 May 2010
NCT00214058 Completed Phase 2 Weekly Carboplatin/Docetaxel for Recurrent Ovarian/Peritoneal Cancer August 2002 February 2006
NCT00305695 Completed Phase 2 Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries November 28, 2005
NCT00445887 Completed Phase 2 Levonorgestrel in Preventing Ovarian Cancer in Patients at High Risk for Ovarian Cancer March 10, 2008
NCT00474669 Completed Phase 1 A Phase I Study of Intraperitoneal Hyperthermic Docetaxel June 2007 December 2009
NCT00623831 Completed Phase 1 A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen May 2007 May 2013
NCT05001347 Completed Phase 2 A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors November 2, 2021 February 8, 2023
NCT00679783 Completed Phase 2 Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer July 8, 2008 July 20, 2022
NCT00721890 Completed Phase 2 Green Tea Intake for the Maintenance of Complete Remission in Women With Advanced Ovarian Carcinoma June 2008 June 2013
NCT00756847 Completed Phase 1 Safety Study of XL147 (SAR245408), in Combination With Paclitaxel and Carboplatin in Adults With Solid Tumors September 2008 October 2012
NCT00853307 Completed Phase 2 MLN8237 for Treatment of Participants With Ovarian, Fallopian Tube, or Peritoneal Carcinoma March 23, 2009 January 27, 2011
NCT00862355 Completed Phase 1 Bioequivalence Study of SPARC147609 in Patients With Ovarian Cancer March 2010 January 2011
NCT00868192 Completed Phase 2 Trial of Pemetrexed and Bevacizumab for Recurrent Ovarian Primary Peritoneal Carcinoma May 2008 December 2012
NCT00892736 Completed Phase 1 Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy April 20, 2009 May 19, 2017
NCT00989651 Completed Phase 1 Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer October 28, 2009 April 10, 2020
NCT01091428 Completed Phase 2 Alisertib (MLN8237) in Participants With Ovarian, Fallopian Tube or Peritoneal Cancer Preceded by Phase 1 Study of MLN8237 Plus Paclitaxel Treatment of Ovary or Breast Cancer April 16, 2010 July 19, 2017
NCT01295489 Completed Biomarkers in Patients With Previously Untreated Invasive Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer March 2011
NCT06422455 Not yet recruiting N/A Access to Genetic Testing in Underserved Patients With Cancer July 1, 2024 July 1, 2027
NCT01445275 Not yet recruiting Cost of Cancer Risk Management in Women at Elevated Genetic Risk for Ovarian Cancer Who Participated on GOG-0199 January 2100
NCT05591560 Not yet recruiting N/A Itraconazole in Advanced Ovarian Cancer October 2022 October 2024
NCT05714306 Not yet recruiting Phase 1/Phase 2 PEP-DC and OC-DC Vaccine in High Grade Serous Ovarian Carcinoma June 2023 March 2030
NCT05949424 Not yet recruiting Phase 4 OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults May 2024 March 2025
NCT06321484 Not yet recruiting Phase 1 Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer May 2024 October 31, 2031
NCT06393543 Not yet recruiting International Registration of Isolated STIC: to Report and Investigate the Risk of Serous Peritoneal Carcinomatosis June 2024 June 2034
NCT04147494 Recruiting Early Phase 1 Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues November 5, 2019 October 17, 2031
NCT04251052 Recruiting N/A A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer September 1, 2020 June 23, 2037
NCT05927818 Recruiting N/A Sentinel Lymph Node Biopsy in Early-Stage Ovarian Cancer April 15, 2023 January 15, 2026
NCT05773859 Recruiting Phase 1/Phase 2 NEOadjuvant Dendritic Cell Vaccination for Ovarian Cancer March 17, 2023 October 2024
NCT05415527 Recruiting N/A Evaluation of Pretreatment Sarcopenia in Patients With Inoperable High-grade Ovarian Carcinoma as Part of Optimised Management June 11, 2022 January 2026
NCT05429970 Recruiting N/A A Study Comparing Perioperative Stress Reduction vs. Standard of Care in Ovarian Cancer (PRESERVE) June 17, 2022 June 17, 2025
NCT06420973 Recruiting Phase 2 RC48 Treatment for Platinum Sensitive Recurrent Ovarian Cancer With HER2 Expression May 16, 2024 September 17, 2027
NCT05494580 Recruiting Phase 1/Phase 2 Pamiparib Plus Surufatinib in Patients With Platinum-resistant Ovarian Cancer September 22, 2022 August 10, 2025
NCT05498597 Recruiting Phase 1 AMT-151 in Patients With Selected Advanced Solid Tumours January 25, 2023 October 30, 2024
NCT05576519 Recruiting Immunohistochemical Expression of Epithelial Cell Adhesion Molecule (EpCAM) in Epithelial Ovarian Carcinoma June 1, 2017 December 30, 2022
NCT06299163 Recruiting Phase 1 NM32-2668 in Adult Patients With Selected Advanced Solid Tumors May 1, 2024 December 31, 2027
NCT05610501 Recruiting Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses. May 1, 2021 April 30, 2024
NCT02073500 Recruiting Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies September 2009 August 2027
NCT03296826 Recruiting Prospective Cohort Study of Germline Variant Carriers With BRCA1 or BRCA2 November 8, 2017 March 31, 2032
NCT03842982 Recruiting Phase 3 Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer (CHIPPI) April 1, 2019 August 1, 2028
NCT04562623 Recruiting Prospective Study of Immune Alterations in Operable Breast and Ovarian Carcinoma July 1, 2021 July 2031
NCT06285097 Recruiting Phase 1 A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors February 8, 2024 April 29, 2028
NCT03150121 Recruiting N/A Biomarkers for Early Detection of Ovarian Cancer Using Uterine Lavage June 29, 2014 December 31, 2024
NCT04686682 Recruiting Phase 1/Phase 2 A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors May 7, 2021 September 2024
NCT04851119 Recruiting Phase 1/Phase 2 Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors November 8, 2021 June 30, 2028
NCT04878094 Recruiting Phase 3 A Study of Intra-operative Imaging in Women With Ovarian Cancer May 3, 2021 May 3, 2025
NCT03604315 Recruiting Phase 1 Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF December 18, 2018 June 30, 2027
NCT06264921 Recruiting Phase 1 A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors February 23, 2024 May 2025
NCT06216561 Recruiting Phase 1 Intraperitoneal LSTA1 in CRS-HIPEC November 30, 2023 December 2029
NCT04981119 Recruiting Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing October 29, 2021 December 2026
NCT04997096 Recruiting N/A Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy April 2, 2022 April 30, 2025
NCT05001282 Recruiting Phase 1/Phase 2 A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα) September 13, 2021 June 15, 2025
NCT06172478 Recruiting Phase 2 A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors February 26, 2024 April 30, 2026
NCT06290193 Recruiting Phase 2 Study of Acute Normovolemic Hemodilution (ANH) in People With Ovarian Cancer Who Are Having Primary Cytoreductive Surgery February 23, 2024 February 23, 2029
NCT06028932 Recruiting Phase 2 A Study of Sacituzumab Govitecan (IMMU-132) in Platinum-resistant Ovarian Cancer Patients January 8, 2024 November 1, 2027
NCT00488878 Recruiting Data Collection for Patients With Low Grade Ovarian or Peritoneal Tumors May 19, 2006 May 1, 2035
NCT01175772 Terminated Phase 2 Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy August 2010 April 2013
NCT02708511 Terminated Phase 1 Copper Cu 64-DOTA-B-Fab PET/CT in Imaging Patients With Ovarian and Breast Cancer August 2016 October 11, 2017
NCT02412124 Terminated N/A Peer-to-Peer Support Program in Improving Quality of Life Outcomes in Patients With Gynecologic Cancer and Their Caregivers July 2015 April 2018
NCT02218502 Terminated N/A Study Into a New Diagnostic Tool (Simple Ultrasound-based Rules) in Patients With Adnexal Masses September 2014 October 1, 2015
NCT03957096 Terminated Phase 1 A Safety Study of SGN-CD47M in Patients With Solid Tumors July 17, 2019 September 14, 2020
NCT01936974 Terminated Phase 2 (PGA) for Platinum-resistant/Refractory, Paclitaxel-Pretreated Recurrent Ovarian and Peritoneal Carcinoma September 2013 August 2015
NCT04442126 Terminated Phase 1/Phase 2 A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors August 19, 2020 February 6, 2024
NCT04628780 Terminated Phase 1 Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors December 16, 2020 May 26, 2023
NCT01312376 Terminated Phase 1 Autologous T-Cells Combined With Autologous OC-DC Vaccine in Ovarian Cancer March 2011 January 2019
NCT05012397 Terminated Phase 2 Milademetan in Advanced/Metastatic Solid Tumors November 1, 2021 October 15, 2023
NCT00312650 Terminated Phase 2 Doxil and Gemcitabine in Recurrent Ovarian Cancer April 2006 May 2006
NCT05261490 Terminated Phase 1/Phase 2 Study of Maplirpacept (PF-07901801) in Combination With PLD in Patients With Platinum-Resistant Ovarian Cancer August 1, 2022 February 15, 2024
NCT00047632 Terminated Phase 3 Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal Cancer October 2001 February 2006
NCT03029585 Terminated Phase 2 Phase II Study of Intraperitoneal NanoPac® in Patients With Ovarian Cancer April 19, 2017 November 4, 2019
NCT03382574 Terminated Early Phase 1 Pilot Study of Denosumab in BRCA1/2 Mutation Carriers Scheduled for Risk-Reducing Salpingo-Oophorectomy March 14, 2019 October 22, 2021
NCT02244502 Unknown status Phase 1/Phase 2 Safety, Feasibility and Effect of TTFields (200 kHz) Concomitant With Weekly Paclitaxel in Recurrent Ovarian Carcinoma (INNOVATE) September 2014 December 2016
NCT03302884 Unknown status N/A Circulating Tumor DNA as an Early Marker of Recurrence and Treatment Efficacy in Ovarian Carcinoma October 10, 2018 October 30, 2023
NCT00154986 Unknown status N/A IGFBP-3 in Ovarian Cancer Invasion August 2004 July 2005
NCT05311579 Unknown status Phase 2 Niraparib Plus Anlotinib for Recurrent Ovarian Cancer March 27, 2022 March 27, 2024
NCT05310344 Unknown status Phase 2 Albumin-bound Paclitaxel and Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer March 27, 2022 March 27, 2024
NCT00715286 Unknown status Phase 3 Neoadjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer (EOC): A Phase III Randomized Study November 2001 June 2009
NCT05180851 Unknown status Early Phase 1 Safety and Efficacy of Recombinant Oncolytic Adenovirus L-IFN Injection in Relapsed/Refractory Solid Tumors Clinical Study November 30, 2021 December 31, 2023
NCT02083536 Withdrawn Phase 1 LDFWART With Docetaxel in Patients With Platinum-Resistant Recurrent Ovarian Carcinoma May 2014
NCT00659399 Withdrawn Phase 1 Feasibility Study of Short Term Fondaparinux (Arixtra) in Chemotherapy-Pretreated Ovarian Carcinoma Patients at High Risk of Progression January 2008 November 2010
NCT02878980 Withdrawn N/A An Exercise Intervention Trial to Reduce Symptoms & Improve Clinical Outcomes of Platinum-Based Treatment in Ovarian Cancer Patients September 2, 2016 December 2018
NCT04602117 Withdrawn Phase 1 ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer July 28, 2021 November 17, 2021
NCT02530606 Withdrawn N/A Photoacoustic Imaging in Detecting Ovarian or Fallopian Tube Cancer September 2016 November 2018
Disase is a (Disease Ontology)
DOID:2151
Cross Reference ID (Disease Ontology)
EFO:0001075
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0677886
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0025318