Respiratory Distress Syndrome, Newborn
Information
- Disease name
- Respiratory Distress Syndrome, Newborn
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT01039285 | Completed | Phase 4 | Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia | December 2009 | June 2022 |
| NCT00368485 | Completed | Phase 1 | Neural Control of Non-invasive Ventilation in the Preterm | August 2006 | June 2008 |
| NCT00486850 | Completed | Phase 4 | Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress | October 2006 | January 2009 |
| NCT00501982 | Completed | Phase 4 | Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Study | March 2007 | May 2008 |
| NCT00556738 | Completed | N/A | Intrapulmonary Percussive Ventilation (IPV) Versus Nasal Continuous Positive Airway Pressure Ventilation (nCPAP) in Transient Respiratory Distress of the Newborn | November 2007 | December 2009 |
| NCT00739115 | Completed | N/A | The Use of Heliox Via Nasal CPAP to Prevent Early CPAP Failure in Premature Infants: A Feasibility Study | September 2008 | August 2011 |
| NCT00751959 | Completed | N/A | Surfactant Application During Spontaneous Breathing With Continuous Positive Airway Pressure (CPAP) in Premature Infants < 27 Weeks | April 2009 | June 2012 |
| NCT00810186 | Completed | Continuous Monitoring of Lung Ventilation | April 2009 | August 2015 | |
| NCT00814099 | Completed | Phase 3 | Sedation Management in Pediatric Patients With Acute Respiratory Failure (The RESTORE Study) | January 2009 | December 2013 |
| NCT00828243 | Completed | Genetic Regulation of Surfactant Deficiency | November 2007 | March 2013 | |
| NCT01042600 | Completed | Phase 4 | Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation | December 2009 | November 2012 |
| NCT01102543 | Completed | Observational Study on the Prophylactic Use of Curosurf in Neonatal Respiratory Distress Syndrome (RDS) | March 2010 | March 2011 | |
| NCT01203488 | Completed | Phase 1/Phase 2 | Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants | January 1996 | July 1999 |
| NCT01242462 | Completed | Phase 1/Phase 2 | Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial | October 2011 | May 2013 |
| NCT01255826 | Completed | Phase 2 | Ventilatory Management of the Preterm Neonate in the Delivery Room | January 2012 | December 2013 |
| NCT01526226 | Completed | N/A | Patient Comfort During High Flow Nasal Cannula Versus Nasal Continuous Airway Pressure (CPAP) | February 2012 | May 2013 |
| NCT01688440 | Completed | Early Phase 1 | ETCare: Safety and Preliminary Efficacy Trial | June 2005 | September 2005 |
| NCT01941524 | Completed | Phase 4 | Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations | March 3, 2013 | June 20, 2015 |
| NCT02267018 | Completed | N/A | Diaphragm Electrical Activity of Preterm Infants on nCPAP Versus NIHFV | August 2016 | June 30, 2020 |
| NCT02294630 | Completed | Phase 1/Phase 2 | Aerosolized Surfactant in Neonatal RDS | December 2014 | July 2020 |
| NCT02332304 | Completed | Phase 3 | Amniotic Fluid Optical Density Determination as a Test for Assessment of Fetal Lung Maturity. | May 2014 | December 2014 |
| NCT02452476 | Completed | Phase 2 | A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC) | January 21, 2016 | May 24, 2018 |
| NCT02788110 | Completed | N/A | Work of Breathing During Non-invasive Ventilation in Premature Neonates | August 2016 | June 2018 |
| NCT02860325 | Completed | N/A | NIV-NAVA Versus Nasal Continuous Positive Airway Pressure (nCPAP) or Non Synchronized NIPPV | August 1, 2016 | December 2017 |
| NCT03081611 | Completed | N/A | RAM Cannula VS Short Nasal Prongs for Delivering NIPPV in Preterm Infants | January 1, 2018 | January 30, 2020 |
| NCT03120585 | Completed | N/A | Fluid Restriction in Respiratory Distress of the Newborn | March 1, 2017 | March 31, 2021 |
| NCT03165305 | Completed | N/A | The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term Infants | April 1, 2018 | June 1, 2019 |
| NCT03366714 | Completed | N/A | RAM Cannula Versus Short Bi-nasal Cannula in Respiratory Distress Syndrome | April 1, 2017 | August 15, 2018 |
| NCT04107090 | Completed | N/A | Role of Lung Ultrasound In Assessment Of Recruitment Maneuvers In Ventilated Preterms With Respiratory Distress Syndrome and Its Correlation With Tracheal IL-6 Level | January 20, 2018 | May 20, 2019 |
| NCT04137783 | Completed | ABCA3 Gene and RDS in Late Preterm and Term Infants | May 1, 2019 | December 1, 2020 | |
| NCT04238273 | Completed | High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure for Respiratory Support of Preterm Neonates | January 31, 2018 | January 1, 2020 | |
| NCT04244890 | Completed | Feasibility of Uninterrupted Infant Respiratory Support Treatment | February 21, 2020 | February 1, 2023 | |
| NCT04333563 | Completed | N/A | Non-invasive Neurally Adjusted Ventilator Assist or Continuous Positive Airway Pressure in Preterm Infants | April 14, 2020 | April 30, 2022 |
| NCT04391634 | Completed | N/A | Cerebral and Circulatory Effects of Neonatal Volume Targeted Ventilation | August 1, 2017 | May 30, 2018 |
| NCT04406142 | Completed | N/A | Surfactant Administration Via Thin Catheter Using a Specially Adapted Video Laryngoscope - the VISUAL Method | July 15, 2018 | February 28, 2022 |
| NCT04500353 | Completed | N/A | Routine Or Selective Application of a Face Mask for Preterm Infants at Birth: the ROSA Trial | October 11, 2020 | May 9, 2023 |
| NCT05260424 | Completed | Predictors for Nasal Intermittent Positive Pressure Ventilation Failure for Premature Infants With Respiratory Distress Syndrome | December 1, 2020 | February 1, 2024 | |
| NCT05399628 | Completed | N/A | LISA Catheter With Marked vs. Unmarked Tip in Extremely Low Birth Weight Infants With RDS | June 6, 2022 | June 11, 2022 |
| NCT05796128 | Completed | N/A | NIPPV vs.nCPAP During LISA Procedure | October 1, 2020 | January 23, 2023 |
| NCT00014859 | Completed | Epidemiology of Surfactant Protein-B Deficiency | June 1, 2001 | April 26, 2024 | |
| NCT00244101 | Completed | Phase 3 | Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress Syndrome | August 2003 | June 2011 |
| NCT05961683 | Not yet recruiting | N/A | Evaluating Pressures During Non-invasive Ventilation Utilizing NIV Plus Software | August 1, 2023 | September 30, 2024 |
| NCT05961670 | Not yet recruiting | Application of Lung Near-Infrared Spectroscopy (NIRS) in Preterm Infants | August 1, 2023 | September 30, 2024 | |
| NCT05629910 | Not yet recruiting | N/A | NeO2Matic-Pilot Trial | January 1, 2024 | July 1, 2025 |
| NCT05594030 | Not yet recruiting | Thoracic Fluid Content by Electric Bioimpedance Versus Lung Ultrasound in Preterm Neonates With Respiratory Distress | November 1, 2022 | December 2023 | |
| NCT05638568 | Not yet recruiting | N/A | Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment | July 1, 2024 | January 1, 2029 |
| NCT05719298 | Not yet recruiting | N/A | Infant Respiratory Interface and Accessories Evaluation Study | February 2023 | January 2026 |
| NCT06394583 | Not yet recruiting | LUS AT BIRTH IN INFANTS BORN BEFORE 26 WEEKS | June 30, 2024 | December 1, 2029 | |
| NCT06446453 | Not yet recruiting | N/A | Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure | June 2024 | May 2025 |
| NCT03346343 | Recruiting | N/A | Pulmonary Function Using Non-invasive Forced Oscillometry | December 6, 2017 | May 2027 |
| NCT05198375 | Recruiting | N/A | Lung UltrasouNd Guided Surfactant Therapy in Preterm Infants (LUNG Study) | April 5, 2022 | July 31, 2024 |
| NCT03938532 | Recruiting | N/A | Feasibility and Impact of Volume Targeted Ventilation in the Delivery Room | July 11, 2019 | December 31, 2024 |
| NCT05427929 | Recruiting | N/A | Measuring Diaphragm Electrical Activity in Neonates Using a Smaller Inter-electrode Distance | January 12, 2023 | June 2024 |
| NCT05065424 | Recruiting | Phase 4 | Premedication for Less Invasive Surfactant Administration Study (PRELISA) | March 14, 2022 | November 2024 |
| NCT04984057 | Recruiting | N/A | Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome | August 1, 2021 | December 31, 2024 |
| NCT04914806 | Recruiting | Infantile NO Replenishment as a New Therapeutic Possibility | June 1, 2021 | December 31, 2025 | |
| NCT02852928 | Recruiting | European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and Biobank | December 2013 | December 2029 | |
| NCT06007547 | Recruiting | Phase 4 | Prophylactic Minimally Invasive Surfactant Evaluation | January 1, 2024 | July 31, 2027 |
| NCT00005776 | Terminated | Phase 3 | Inhaled Nitric Oxide Study for Respiratory Failure in Newborns | October 1995 | May 1998 |
| NCT00139256 | Terminated | Phase 2/Phase 3 | Antepartum Betamethasone Treatment for Prevention of Respiratory Distress in Infants Born by Elective Cesarean Section | August 2005 | September 2007 |
| NCT00215540 | Terminated | Phase 2 | SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants. | February 2005 | July 2006 |
| NCT00486395 | Terminated | Phase 3 | Will CPAP Reduce Length Of Respiratory Support In Premature Infants? | September 2007 | February 2011 |
| NCT00599651 | Terminated | N/A | Randomized Controlled Trial of Surfactant Administration by Laryngeal Mask Airway (LMA) | June 2005 | December 2009 |
| NCT03121612 | Terminated | N/A | Comparison of CPAP Machines With Reusable vs Disposable Circuits | August 1, 2017 | October 15, 2018 |
| NCT00005773 | Terminated | Phase 3 | Early Inhaled Nitric Oxide for Respiratory Failure in Newborns | August 1998 | August 2003 |
| NCT01467076 | Terminated | Phase 2 | Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) | November 2011 | June 2012 |
| NCT04264156 | Terminated | Phase 2 | A Safety and Efficacy Study of Lucinactant for Inhalation in Preterm Neonates 26 to 32 Weeks Gestational Age | April 18, 2020 | March 28, 2021 |
| NCT02164734 | Terminated | Phase 4 | Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome | June 2014 | December 31, 2020 |
| NCT02168257 | Terminated | N/A | Neotech RAM Cannula Versus Conventional Binasal Prong Continuous Positive Airway Pressure (CPAP) to Treat Respiratory Distress in Low Birth Weight Neonates | June 2014 | February 2017 |
| NCT02340299 | Terminated | N/A | Nasal HFOV Versus Nasal CPAP to Reduce Post-extubation pCO2 | January 1, 2015 | December 31, 2017 |
| NCT01959009 | Unknown status | N/A | High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Blood Oxygenation and Stability of Oxygenation | August 2014 | June 2022 |
| NCT02050971 | Unknown status | Phase 1 | Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonates | October 2010 | December 2015 |
| NCT05230485 | Unknown status | N/A | Optimal High CPAP Pressures in Preterm Neonates Post-extubation | February 15, 2022 | February 15, 2024 |
| NCT01206946 | Unknown status | Phase 2 | Efficacy of Antenatal Steroids in Reducing Respiratory Morbidities in Late Preterm Infants | September 2010 | September 2013 |
| NCT03422549 | Unknown status | N/A | Diaphragmatic Electrical Activity in Preterm Infants on Non-Invasive Ventilation | July 1, 2018 | February 1, 2020 |
| NCT01173237 | Unknown status | Phase 4 | Efficacy Evaluation of Surfactant Administration Via Laryngeal Mask Airway | July 2011 | July 2013 |
| NCT02835209 | Withdrawn | Positioning During SBT in NICU Infants | November 2017 | September 2018 | |
| NCT03996317 | Withdrawn | N/A | Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities | June 2021 | December 30, 2022 |
| NCT00598429 | Withdrawn | Phase 2 | Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure | May 2008 | September 2008 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D012127