Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL10 MUTATION
IL10 MUTATION - Associated Disease
- Metabolic Diseases
- Source Database
- DisGeNET
- Description
- Adoptive transfer of B-1a cells into HFD-fed B cell-deficient mice rapidly improves insulin resistance and glucose tolerance through IL-10 and polyclonal IgM-dependent mechanisms, whereas transfer of B-2 cells worsens metabolic disease.
- Pubmed
- 25249575
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs