Metabolic Diseases

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Information
Disease name
Metabolic Diseases
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06060509 Active, not recruiting N/A Study on the Effects of Wheat and Corn Germ Blend Oil on Antioxidation and Immune Regulation of Dyslipidemia Population March 1, 2023 November 30, 2023
NCT01745471 Active, not recruiting Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL) December 6, 2012 June 2024
NCT01174875 Active, not recruiting Growing Up in Singapore Towards Healthy Outcomes June 2009 July 2029
NCT05256654 Active, not recruiting Phase 2 A Study of LY3561774 in Participants With Mixed Dyslipidemia July 20, 2022 June 3, 2024
NCT02710370 Active, not recruiting Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans February 2016 August 31, 2026
NCT00192621 Completed Phase 4 Seronegatives and Metabolic Abnormalities Protocol 2 (SAMA002): Study to Compare the Effect of Kaletra and Combivir® in HIV-Negative Healthy Subjects November 2004 December 2006
NCT00362180 Completed Phase 2 Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration July 2006 September 2010
NCT00446264 Completed Phase 2 Islet Allotransplantation With Steroid Free Immunosuppression May 2003 February 2009
NCT00477594 Completed Phase 2 Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia May 2007 July 2011
NCT00550706 Completed Drug Utilization Prevalence in a Pediatric Care Medical Center October 2007 April 2008
NCT00607373 Completed Phase 3 Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia July 2007 March 2009
NCT00622765 Completed Phase 2 A Study of the Safety and Effectiveness of JNJ-16269110 (R256918) in Overweight and Obese Patients November 2007 June 2008
NCT00686491 Completed Respiratory Health of Elite Athletes June 2007 December 2010
NCT00694109 Completed Phase 3 An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia April 2008 September 2014
NCT00707746 Completed Phase 2 Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects October 2008 January 2011
NCT01041677 Completed Phase 2 A Study of the Safety of R256918 in Obese Patients February 2008 October 2008
NCT01103245 Completed Phase 1 Aldosterone and the Metabolic Syndrome March 2010 September 2013
NCT01237574 Completed Multicentre Prospective Cohort Study of Patients With Chronic Alcoholic and/or Metabolic Liver Disease November 23, 2010 December 12, 2020
NCT00119379 Completed Phase 2 Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adults April 2005 October 2008
NCT00119405 Completed Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs) April 2005 November 2010
NCT00128154 Completed N/A Chromium Picolinate for the Treatment of Metabolic Syndrome January 2004 December 2005
NCT00129792 Completed N/A Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome January 2005 April 2014
NCT01301456 Completed Phase 1 Single-Dose And Multiple-Dose Safety And Tolerability Study Of PF-04856883 In Type 2 Diabetic Adult Females March 2011 April 2012
NCT01435382 Completed Phase 1 A Pharmacokinetic and Pharmacodynamic Study of PF-04950615 (RN316) in Subjects With Hypercholesterolemia October 2011 April 2012
NCT01435603 Completed N/A Intervening in Diabetes With Healthy Eating, Activity, and Linkages To Healthcare - The I-D-HEALTH Study August 2011 September 2016
NCT01454232 Completed N/A Adaptation of Human Gut Microbiota to Energetic Restriction June 7, 2011 September 14, 2018
NCT01474161 Completed Phase 1 Comparative Bioavailability - Gender Effect - Single and Multiple Ascending Dose Safety and Pharmacokinetic Study of GFT505 November 2011 November 2012
NCT01616082 Completed N/A Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II) September 2011 November 2012
NCT01655017 Completed N/A Fibrosis a New Pathological Actor in Adipose Tissue February 8, 2012 April 6, 2018
NCT01681173 Completed N/A OPTIFIT-Optimal Fiber Trial for Diabetes Prevention May 2010 December 2014
NCT01705782 Completed N/A The Effects of Amino Acid Supplement During Acute Inflammation. October 2012 December 2013
NCT01708681 Completed N/A Lean Seafood Intake and Postprandial Metabolism October 2012 September 2015
NCT01719913 Completed N/A The Effect of Gluten on Gut Microbiome and Metabolic Health. October 2012 November 2013
NCT01723748 Completed N/A Somatostatin Analogue Treatment of Acromegaly: Molecular Aspects December 2012 May 2015
NCT01737164 Completed N/A Effect of Age on Glucose and Lipid Metabolism September 2010 December 2015
NCT01792986 Completed N/A The Fasting II Study February 2013 June 2013
NCT01917760 Completed Pharmacokinetics Study of Gamma-aminobutyric Acid July 2013 December 2014
NCT01935791 Completed N/A Investigating Brown Adipose Tissue Activation in Humans July 2013 November 5, 2018
NCT01968720 Completed Phase 2 Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia October 2013 April 2014
NCT02102737 Completed Phase 2 Comparison of A New Technique of Measure of the Insulin Resistance By Scintigraphy With the Reference Technique May 13, 2014 March 2018
NCT02135575 Completed N/A Effects of Exercise Training on Cardiovascular Health in Middle-aged Women May 2014 July 2017
NCT02275429 Completed N/A Metabolic Disorders in Ultramarathon Runners During and After the Reunion Island Madmen's Diagonal October 2014 November 2014
NCT02380846 Completed N/A The Metabolic Effects of Consuming Carbohydrate With Different Protein Types September 2013 October 8, 2018
NCT02402985 Completed N/A Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics September 2013 March 2015
NCT02449148 Completed N/A Nutrition and Energy Restriction for Cancer Prevention May 2015 May 2017
NCT02455765 Completed N/A Glycemic Response of Co-ingesting Carbohydrate and Amino Acids June 2014 October 2015
NCT02644759 Completed Phase 1/Phase 2 Transplantation of Autologous Stem Cells for the Treatment of Type 1 Diabetes Mellitus February 2014 May 2018
NCT02715063 Completed N/A Cardiometabolic HIIT-RT Study January 2016 January 2017
NCT02738385 Completed N/A Intensity Training and Cardiovascular Health in Colombian Adults June 2015 October 2016
NCT02782208 Completed N/A Lipolytic Effects of GH in Hypopituitary Patients in Vivo February 10, 2016 December 22, 2016
NCT02782221 Completed N/A Lipolytic Effects of GH in Human Subjects in Vivo May 30, 2016 January 15, 2017
NCT02789683 Completed N/A Effects of Emulsification and Lipid Droplet Size on Postprandial Metabolic Responses July 2015 September 2016
NCT02929472 Completed N/A Effect of a Multicomponent Intervention in Children and Adolescents May 2015 November 2015
NCT03199638 Completed N/A Exercise Snacks and Glutamine to Improve Glucose Control in Adolescents With Type 1 Diabetes April 1, 2016 June 30, 2017
NCT03358745 Completed N/A Impact of Meal Order on Postprandial Cardiometabolic Risk Markers June 1, 2016 December 1, 2018
NCT03941392 Completed Nutritional Study in Spanish Pediatric Population October 2, 2018 August 31, 2019
NCT04539340 Completed Phase 1 A Multi-cohort Study of the Tolerance, Safety, and Pharmacokinetics of GNR-055 in Healthy Volunteers February 28, 2020 September 8, 2020
NCT04977739 Completed Research on the Application and Mechanism of New Biological Probes in Biomedicine August 3, 2021 July 25, 2022
NCT01196533 Completed N/A A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters August 2010 August 2014
NCT00111358 Completed N/A Study of Lifestyle Modification in HIV Lipodystrophy June 2003 October 2006
NCT00628199 Enrolling by invitation Study to Create Potential Cell-Based Therapies to Treat Human Disease and Disability September 2007 January 2030
NCT06138821 Not yet recruiting Phase 4 ESG vs GLP-1RA vs ESG + GLP-1RA in Patients With Obesity, NAFLD and Advanced Fibrosis: A Randomized Controlled Trial July 2024 December 2025
NCT06000605 Not yet recruiting N/A Brain Substrate Switch to Ketones and Lactate October 1, 2023 January 1, 2024
NCT02663388 Recruiting Epigenetic Mechanisms and Severe Obesity (Biological Tissue Collection) January 2016 January 2026
NCT06017986 Recruiting N/A The Effect of Processing on Food Reward July 1, 2023 July 1, 2026
NCT04958109 Recruiting Phase 1 Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test October 28, 2021 August 2024
NCT05272670 Recruiting N/A Digital Foot Self-Management Program for Older-Diabetes February 15, 2022 August 31, 2022
NCT05208281 Recruiting Phase 2/Phase 3 A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II November 30, 2021 March 2028
NCT05894122 Recruiting Evaluation of Capillary Blood Collection Devices (Mitra® and HemaPEN®) December 13, 2023 December 12, 2025
NCT05236374 Recruiting N/A Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc October 1, 2022 September 4, 2025
NCT02650622 Recruiting Genetic and Metabolic Disease in Children June 2015 May 2025
NCT06003153 Recruiting Phase 4 GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH March 12, 2024 May 31, 2027
NCT04168580 Recruiting Phase 1/Phase 2 Brown Adipose Tissue as a Therapeutic for the Metabolic and Cardiac Dysfunction With Senescence (BATSR) November 7, 2019 December 2024
NCT06425042 Recruiting N/A Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity March 1, 2024 March 2026
NCT06301243 Recruiting N/A Molecular Signature of Inactivity Induced Exercise Responsiveness January 1, 2024 December 31, 2025
NCT00387114 Terminated Phase 3 Effect of an Anti-Oxidant Treatment on Resistin Serum Levels.A Randomized Study June 2005 November 2005
NCT02512679 Terminated Phase 2 Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells February 2007 February 2014
NCT02440945 Terminated N/A Use of the DBS for the Follow-up of Blood Clinical Parameters of Old People October 16, 2013 October 16, 2015
NCT01963650 Terminated Natural History Study of Children With Metachromatic Leukodystrophy November 2, 2015 April 8, 2016
NCT02292121 Terminated N/A Intestinal Permeability in Obesity February 24, 2014 March 17, 2016
NCT01345578 Terminated Phase 1 Hepatocyte Transplantation for Liver Based Metabolic Disorders March 2011 March 31, 2022
NCT00935766 Terminated Phase 3 Effect of Fish Oil (Omega-3 Fatty Acids) on Arteries September 2009 March 2012
NCT02903199 Unknown status N/A Whey Protein Effect on Glycaemic and Appetite Responses in T2D July 2015 October 2016
NCT01317186 Unknown status The Role of FGF23 and Asymmetric Dimethylarginine (ADMA) in Chronic Kidney Disease March 2011
NCT02629926 Unknown status Transitional Growth Hormone (GH) Use in Growth Hormone Deficient (GHD) Cancer Survivors October 2010
NCT01475682 Unknown status Long Term Cardiovascular Complications in Men With Obstructive Sleep Apnea November 2011 May 2015
NCT02677831 Unknown status Healthy Aging Longitudinal Study in Taiwan July 2008 December 2020
NCT00707668 Unknown status Chung-ju Metabolic Disease Cohort (CMC) Study May 2007 February 2016
NCT05284162 Unknown status N/A Health Coaching Programme on Health Promoting Behaviours in Middle-Aged Adults With Cardiometabolic Risk April 1, 2021 March 1, 2023
NCT00997165 Unknown status Impact of Adipose Tissue Repartition on the Time Course of Vascular Dysfunction - the NUMEVOX Cohort March 2008 March 2017
NCT02917655 Unknown status N/A P.A.R.Q.V.E III - Comparison of the Educational Program With and Without Multidisciplinary Care November 1, 2016 July 15, 2021
NCT01916603 Unknown status N/A Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development September 2013 March 2017
NCT02119572 Unknown status N/A Impact of Peer Support on Diabetes in China
NCT04429737 Unknown status N/A The Effects of Freshwater Clam Extract on Blood Sugar, and Lipid Profile in Prediabetes Patients March 1, 2017 March 2022
NCT02305914 Unknown status Follow-up Study of Complications of Acute Pancreatitis November 2014 May 2016
NCT01927913 Withdrawn Phase 2 Treatment of Iron Overload Requiring Chelation Therapy November 20, 2014 October 30, 2015
MeSH unique ID (MeSH (Medical Subject Headings))
D008659