Barrett esophagus
Information
- Disease name
- Barrett esophagus
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05846971 | Active, not recruiting | N/A | Clinical Utility of Methylation-based Prognostic Assay for Barrett's Esophagus | January 26, 2021 | December 31, 2023 |
| NCT00431756 | Active, not recruiting | Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus | May 1, 2002 | May 1, 2025 | |
| NCT03459339 | Active, not recruiting | N/A | Coordinating Center: Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy | April 4, 2017 | December 2026 |
| NCT02994693 | Active, not recruiting | Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy | December 2016 | December 2027 | |
| NCT05578677 | Active, not recruiting | N/A | Endoscopic Biopsy Techniques in Barrett's Esophagus Patients | June 23, 2021 | December 30, 2024 |
| NCT03835663 | Active, not recruiting | The Bacterial Composition of the Stomach in Reflux Disease | June 4, 2018 | December 31, 2024 | |
| NCT02521285 | Active, not recruiting | Phase 2 | Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation | January 15, 2016 | March 5, 2025 |
| NCT00576498 | Completed | N/A | Novel Imaging Techniques in Barrett's Esophagus | October 2005 | May 2009 |
| NCT00587652 | Completed | Methylene Blue Chromoendoscopy in Barrett's Esophagus | December 2002 | December 2009 | |
| NCT00795184 | Completed | N/A | Detection Of Neoplastic Tissue in Barrett's Esophagus With In vivO Probe-based Confocal Endomicroscopy | November 2008 | February 2010 |
| NCT00848237 | Completed | N/A | HALO Patient Registry: Ablation of Barrett's Esophagus | July 2007 | July 2014 |
| NCT00955019 | Completed | Novel Method of Surveillance in Barrett's Esophagus | October 2007 | September 2009 | |
| NCT01032044 | Completed | N/A | CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia | February 2010 | April 2011 |
| NCT01097304 | Completed | Phase 2 | Ursodiol in Treating Patients With Barrett Esophagus and Low-Grade Dysplasia | April 2010 | July 2014 |
| NCT01391208 | Completed | Phase 1 | Esophageal Protocol for Detection of Neoplasia in the Digestive Tract | February 2011 | June 2012 |
| NCT01447927 | Completed | Phase 2 | Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus | June 2012 | September 2013 |
| NCT04656392 | Completed | N/A | Early Detection of Barrett's Esophagus in Participants With Reflux Symptoms in Primary Care | April 20, 2021 | March 11, 2024 |
| NCT00233935 | Completed | Phase 1 | Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus | November 2005 | November 2010 |
| NCT00282672 | Completed | N/A | Ablation of Intestinal Metaplasia Containing Dysplasia | February 2006 | August 2014 |
| NCT00411151 | Completed | Phase 2 | Efficacy and Safety of Sunitinib in Metastatic Gastric Cancer | December 2006 | August 2009 |
| NCT00449995 | Completed | N/A | Confocal Laserscanning Microscopy for Detection of Barretts Esophagus | March 2007 | November 2008 |
| NCT00474903 | Completed | Phase 2 | Esomeprazole Magnesium With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett Esophagus | April 2007 | June 2011 |
| NCT00489268 | Completed | N/A | Micro-Layer Ablation of Barrett's Metaplasia- A Two-Phase, Multi-Center Trial - Extension of Follow-up to 5 Years | November 2003 | October 2009 |
| NCT01802203 | Completed | trūFreeze® Spray Cryotherapy Patient Registry | April 2013 | April 2022 | |
| NCT02199002 | Completed | N/A | Acid Pocket: Position and Aspiration | July 2014 | December 31, 2017 |
| NCT02284802 | Completed | N/A | Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy | September 10, 2014 | March 10, 2023 |
| NCT02451124 | Completed | N/A | Non-endoscopic Brushing of the Esophagus Using a Non-endoscopic Inflatable Balloon of the Esophagus in Screening for Barrett Esophagus | July 2015 | January 29, 2017 |
| NCT02455648 | Completed | N/A | Autologous Cell Sheets Transplantation After ESD in the Esophagus | January 2012 | March 25, 2018 |
| NCT02549053 | Completed | N/A | Prevalence of Human Papillomavirus in Barrett Esophagus Compared With Controls | February 2012 | February 2015 |
| NCT02560623 | Completed | N/A | A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus | October 15, 2015 | July 8, 2021 |
| NCT02606292 | Completed | Early Phase 1 | Photoacoustic Endoscopy of Barrett's Esophagus | August 2014 | August 2016 |
| NCT02688114 | Completed | N/A | Healing of the Esophageal Mucosa After RFA of Barrett's Esophagus | October 18, 2017 | January 29, 2020 |
| NCT02729948 | Completed | N/A | Tethered Capsule Endoscope in Screening Patients With Barrett Esophagus | July 28, 2016 | August 3, 2017 |
| NCT02890979 | Completed | N/A | Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease | August 3, 2016 | October 10, 2017 |
| NCT03008980 | Completed | WATS3D for the Detection of Esophageal Dysplasia | May 2014 | December 2018 | |
| NCT03015389 | Completed | Wide Area Transepithelial Sample Esophageal Biopsy Combined With Computer Assisted 3-Dimensional Tissue Analysis (WATS3D) For the Detection of High Grade Esophageal Dysplasia and Adenocarcinoma | September 27, 2017 | February 18, 2019 | |
| NCT03060642 | Completed | The Microenvironment in Barrett's Esophagus | February 1, 2018 | November 30, 2022 | |
| NCT03073226 | Completed | N/A | A Prospective Study Comparing the Accuracy of Olympus Lucera Spectrum Technology vs Olympus Lucera Elite Technology in the in Vivo Diagnosis of Barrett's Oesophagus and Colorectal Polyps: The ELITE Study | February 6, 2016 | February 6, 2018 |
| NCT03097666 | Completed | N/A | Evaluation of Safety and Dose Response Using C2 CryoBalloon™ Swipe Ablation System for Barrett's Esophagus | March 20, 2017 | November 1, 2018 |
| NCT03167970 | Completed | Evaluation of Performance Characteristics of Capsule Endoscopy With PillCam UGI Capsule Compared to Standard Endoscopy | May 3, 2017 | January 14, 2018 | |
| NCT03191604 | Completed | Impact of NBI on Patients Undergoing Endoscopic Eradication Therapy | November 1, 2017 | May 10, 2019 | |
| NCT03205501 | Completed | Phase 1 | Molecular Fluorescence Endoscopy of (Pre)Malignant Esophageal Lesions | February 9, 2017 | September 1, 2019 |
| NCT03375060 | Completed | Histology Post-Endoscopic Eradication Therapy (EET) | August 2, 2017 | November 5, 2017 | |
| NCT03387982 | Completed | Balloon Cryotherapy vs. Radiofrequency Ablation Pain Study | November 1, 2017 | February 16, 2021 | |
| NCT03388047 | Completed | N/A | Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus | January 1, 2018 | December 31, 2020 |
| NCT03434834 | Completed | N/A | OCT Pilot in Esophagus | September 25, 2018 | March 25, 2020 |
| NCT03468634 | Completed | N/A | Raman Probe for In-vivo Diagnostics (During Oesophageal) Endoscopy | September 21, 2023 | April 23, 2024 |
| NCT03589443 | Completed | Phase 1 | Study of Multiplexed Heptapeptides for Detection of Neoplasia in the Esophagus | May 10, 2018 | February 4, 2019 |
| NCT03859557 | Completed | The Evaluation of Patients With Esophageal and Foregut Disorders With WATS (Wide Area Transepithelial Sample With 3-Dimensional Computer-Assisted Analysis) vs. 4-Quadrant Forceps Biopsy | October 1, 2017 | December 31, 2018 | |
| NCT03990025 | Completed | N/A | Linked Color Imaging vs White Light Imaging for Detection of Gastric Cancer Precursors | March 27, 2019 | October 17, 2020 |
| NCT04293458 | Completed | N/A | Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BE | February 28, 2020 | August 22, 2022 |
| NCT04301986 | Completed | N/A | Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's Esophagus | August 11, 2020 | May 10, 2022 |
| NCT04329000 | Completed | N/A | On-demand PPI Therapy is Effective on Controlling Symptoms in Patients With Barrett's Esophagus. | February 2, 2010 | December 8, 2019 |
| NCT04392167 | Completed | N/A | a/LCI-OCT Pilot in Esophagus | November 24, 2020 | November 29, 2022 |
| NCT04587310 | Completed | Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study | October 1, 2008 | September 20, 2020 | |
| NCT00217087 | Completed | Phase 2 | Endoscopic Therapy of Early Cancer in Barretts Esophagus | September 2005 | June 2012 |
| NCT05200325 | Completed | N/A | Clinical Utility Evidence for TissueCypher® | June 6, 2021 | December 15, 2021 |
| NCT05628441 | Completed | Real-time Computer Aided Detection of Barrett's Neoplasia | May 16, 2022 | October 13, 2022 | |
| NCT06381583 | Completed | A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma | April 15, 2023 | April 24, 2024 | |
| NCT03853772 | Enrolling by invitation | The Johns Hopkins Heartburn Center Registry | April 27, 2019 | December 2025 | |
| NCT04561791 | Enrolling by invitation | N/A | Evaluation of Tethered Capsule Endomicroscopy as a Screening Tool for Barrett's Esophagus in the Primary Care Setting | January 2, 2019 | December 31, 2029 |
| NCT05216133 | Enrolling by invitation | Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN) | March 22, 2023 | July 2024 | |
| NCT04457193 | Enrolling by invitation | Outcomes After Transoral Incisionless Fundoplication (TIF) Following Successful Endoscopic Ablation for Barrett's Esophagus | June 7, 2018 | June 7, 2027 | |
| NCT03311451 | Enrolling by invitation | N/A | C2 CryoBalloon™ 180 Ablation System Dose De-escalation Study. | January 16, 2023 | December 1, 2025 |
| NCT06008522 | Not yet recruiting | N/A | Safety and Feasibility of Immuno-OCT | April 1, 2024 | March 1, 2025 |
| NCT05706025 | Not yet recruiting | Phase 1 | Pilot Study to Evaluate Utility of EnteroTracker® as a Minimally Invasive Sampling Method to Screen for Barrett's Esophagus and Esophageal Cancer | March 1, 2023 | June 1, 2025 |
| NCT03546660 | Not yet recruiting | N/A | Imaging of the Esophagus Using a SECM Capsule | January 1, 2025 | December 30, 2027 |
| NCT06346054 | Not yet recruiting | N/A | Molecular Assessment for Gastro-Esophageal Cancer | July 1, 2024 | July 1, 2029 |
| NCT05107219 | Recruiting | Phase 1 | GCC Agonist Signal in the Small Intestine | November 30, 2022 | February 1, 2025 |
| NCT05530343 | Recruiting | N/A | Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance | October 3, 2022 | March 2026 |
| NCT03427346 | Recruiting | N/A | Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection | December 2016 | October 2025 |
| NCT03554356 | Recruiting | N/A | Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE) | September 4, 2018 | December 2026 |
| NCT05642338 | Recruiting | A Multicenter Prospective Cohort Study Comparing Random Biopsies Versus Wide-Area Transepithelial Brush-Sampling (WATS) for Surveillance of Barrett's Esophagus, the WATS-EURO2 Study | November 1, 2022 | May 1, 2027 | |
| NCT03830801 | Recruiting | N/A | Pilot Study for OCT Guided In Vivo Laser Capture Microdissection for Assessing the Prognosis of Barrett's Esophagus | December 6, 2017 | December 2026 |
| NCT05690958 | Recruiting | Public's Intended Uptake and Views on Organization of Esophageal Cancer Screening | February 13, 2023 | July 1, 2023 | |
| NCT03961945 | Recruiting | N/A | Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma | July 1, 2021 | January 2, 2027 |
| NCT04001478 | Recruiting | Non-invasive Testing for Early oEesophageal Cancer and Dysplasia | October 1, 2019 | October 31, 2024 | |
| NCT04214119 | Recruiting | EsophaCap for the Detection of Early Esophageal Carcinoma | January 12, 2016 | December 19, 2025 | |
| NCT05753748 | Recruiting | N/A | Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia | January 24, 2023 | February 1, 2028 |
| NCT04295811 | Recruiting | N/A | Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC | June 18, 2020 | December 2023 |
| NCT05778851 | Recruiting | N/A | Clinical Utility of a Non Endoscopic Device EsoCheck and Biomarker EsoGuard as Alternative to Endoscopy for Screening for Barrett's Esophagus in At Risk Population | April 12, 2023 | June 1, 2024 |
| NCT04312633 | Recruiting | Clinical Utility of WATS3D: A 5-Year Prospective Study | April 1, 2020 | April 1, 2025 | |
| NCT05965999 | Recruiting | Lucid Registry Study | April 11, 2023 | June 1, 2024 | |
| NCT06030180 | Recruiting | N/A | CLUE: CLinical Utility Study of EsoGuard | February 23, 2023 | September 29, 2023 |
| NCT04867590 | Recruiting | N/A | A Study Comparing the Effectiveness of EndoRotor Versus Radiofrequency in Treating Barrett's Esophagus | March 25, 2022 | May 2027 |
| NCT04939051 | Recruiting | Phase 2 | Obeticholic Acid for Prevention in Barrett's Esophagus | January 3, 2024 | September 29, 2026 |
| NCT05051475 | Recruiting | N/A | Endoscopic Radiofrequency Ablation Versus Hybrid Argon Plasma Coagulation in the Treatment of Barrett's Esophagus | December 1, 2021 | December 31, 2023 |
| NCT05056051 | Recruiting | N/A | Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus | October 1, 2020 | June 30, 2025 |
| NCT05524844 | Recruiting | The Microbiome, Bile Acids, and Notch in Barrett's Esophagus (BE) | February 9, 2021 | December 2025 | |
| NCT05133102 | Recruiting | Longitudinal Oral Microbiome Sampling for BE | March 19, 2021 | August 2025 | |
| NCT06071845 | Recruiting | N/A | Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples | October 16, 2023 | December 1, 2025 |
| NCT05210049 | Recruiting | N/A | Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in Veterans | March 1, 2022 | August 31, 2024 |
| NCT05229783 | Recruiting | N/A | High Resolution Virtual Chromoendoscopy Versus Seattle Protocol for the Surveillance of Barrett's Esophagus | May 11, 2022 | September 30, 2025 |
| NCT05247346 | Recruiting | N/A | Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo Measurements | July 1, 2022 | December 1, 2024 |
| NCT05463796 | Recruiting | InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer | April 25, 2023 | March 25, 2032 | |
| NCT05468008 | Recruiting | Endoscopic Submucosal Dissection (ESD) | February 4, 2022 | December 2027 | |
| NCT03222635 | Recruiting | N/A | Prospective Endoscopic Follow-up of Patients With Submucosal and High Risk Mucosal Esophageal Adenocarcinoma | July 25, 2017 | July 25, 2028 |
| NCT03366012 | Suspended | N/A | Rapid Assessment of Esophageal Adenocarcinoma Risk Test | August 1, 2018 | December 2024 |
| NCT03852576 | Terminated | Phase 1 | Phase 1B Study of KSP/QRH Dimer for Detection of Neoplasia in the Esophagus | May 9, 2019 | November 18, 2020 |
| NCT02988934 | Terminated | The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. Registry | April 2016 | February 7, 2023 | |
| NCT00321958 | Terminated | Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal Cancer | April 2006 | May 2007 | |
| NCT05579444 | Terminated | Systems Biology of Gastrointestinal and Related Diseases | November 11, 2022 | November 29, 2023 | |
| NCT04642690 | Terminated | Nitrates and IL-8 in Barrett's Esophagus | September 24, 2020 | December 9, 2022 | |
| NCT00576992 | Terminated | Demographics and Findings of Upper Endoscopy Patients | January 2003 | May 2017 | |
| NCT02396745 | Terminated | N/A | TECR & ECM Placement for Esophageal High Grade Dysplasia | January 25, 2016 | March 22, 2018 |
| NCT01129778 | Terminated | N/A | Assessment of Zegerid on Esophageal pH in Patients With Barrett's Esophagus | November 2009 | December 2010 |
| NCT03417570 | Terminated | N/A | Cap Assisted Upper Endoscopy Versus High Definition White Light Endoscopy and Narrow Band Imaging Alone In The Detection Of Visible Lesions Barrett's Esophagus: A Randomized Tandem Study | December 22, 2017 | November 17, 2021 |
| NCT00386594 | Terminated | N/A | Pilot Study of Oral 852A for Elimination of High-Grade Dysplasia in Barrett's Esophagus | October 2006 | October 2012 |
| NCT04151524 | Unknown status | Classification of Adenocarcinoma of the Esophagogastric Junction | October 23, 2019 | February 1, 2020 | |
| NCT03216135 | Unknown status | Microbiome Involvement With Barrett's Esophagus and Progression to Esophageal Adenocarcinoma | July 20, 2017 | December 2017 | |
| NCT03228407 | Unknown status | N/A | Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD) | April 28, 2017 | June 2018 |
| NCT04400136 | Unknown status | Early Phase 1 | PPI Therapy Impact on GERD After Sleeve Gastrectomy | July 1, 2020 | September 1, 2022 |
| NCT03471052 | Unknown status | N/A | Radiofrequency Ablation vs Sham Procedure for Symptomatic Cervical Inlet Patch | March 6, 2018 | September 30, 2021 |
| NCT04478929 | Unknown status | Early Detection of Barrett's Esophagus Through Deep Image Retrieval | August 2020 | August 2021 | |
| NCT01776346 | Unknown status | Barrett's Esophagus Patient Registry | January 2011 | December 2021 | |
| NCT04621474 | Unknown status | Non-magnified NBI in Barrett's Oesophagus Neoplasia Detection and Delineation | April 8, 2019 | April 8, 2021 | |
| NCT02310230 | Unknown status | N/A | An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI Endoscopy | September 2014 | December 2016 |
| NCT02407392 | Unknown status | N/A | "Using Dilute Vinegar to Find Changes in Cells During Endoscopy for Patients With Barrett's Oesophagus" (The ABBA Study) | July 2015 | September 2017 |
| NCT04818476 | Unknown status | Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus | February 10, 2020 | December 31, 2022 | |
| NCT02478996 | Unknown status | N/A | Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy | August 2015 | June 2019 |
| NCT02514525 | Unknown status | N/A | Multi-center Clinical Study to Evaluate the C2 CryoBalloon Focal Ablation System | March 2016 | June 2023 |
| NCT01618643 | Unknown status | Aceto-whitening in the Assessment of Gastrointestinal Neoplasia | November 2010 | November 2013 | |
| NCT04843397 | Unknown status | Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study | June 1, 2021 | September 15, 2022 | |
| NCT03877601 | Unknown status | Phase 2 | Detection of Early Esophageal Cancer by NIR-FME. | July 29, 2019 | October 1, 2021 |
| NCT03329534 | Unknown status | N/A | Gluten Related Disorders in Barrett's Esophagus | April 1, 2018 | December 30, 2018 |
| NCT02583087 | Unknown status | ESD for the Treatment of Early Barrett's Neoplasia | January 2, 2016 | April 2022 | |
| NCT01209013 | Withdrawn | Phase 3 | Safety of Photodynamic Therapy (PDT) in the Ablation of High-grade Dysplasia (HGD) in Barrett's Esophagus (BE) | ||
| NCT02004782 | Withdrawn | Phase 4 | Barretts oEsophageal Resection With Steroid Therapy Trial | March 2022 | June 2022 |
| NCT03670134 | Withdrawn | N/A | Predict Recurrence of Barrett's Esophagus After Complete Eradication of Intestinal Metaplasia | August 6, 2018 | October 2022 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0100580
- MeSH unique ID (MeSH (Medical Subject Headings))
- D001471