Advanced cancer

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Disease name
Advanced cancer
Disease ID
Description
Disease area statistics
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Chromosome band
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Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03459222 Active, not recruiting Phase 1/Phase 2 An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have Spread May 30, 2018 November 10, 2026
NCT03561207 Active, not recruiting 3D Prediction of Patient-Specific Response June 11, 2018 December 2024
NCT05990920 Active, not recruiting Phase 1 Study of Allogeneic Blood-derived Natural Killer Cells to Evaluate Safety and Tolerability in Cancer Refractory to Conventional Therapy August 23, 2023 December 2024
NCT02743494 Active, not recruiting Phase 3 An Investigational Immuno-therapy Study of Nivolumab or Placebo in Participants With Resected Esophageal or Gastroesophageal Junction Cancer July 14, 2016 October 11, 2025
NCT03761017 Active, not recruiting Phase 1 MGD019 DART® Protein in Unresectable/Metastatic Cancer December 12, 2018 December 2024
NCT02069067 Active, not recruiting Observational Study of Incidence of Breakthrough Cancer Pain and How it is Treated December 2011 December 2023
NCT05663710 Active, not recruiting Phase 1/Phase 2 Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC June 30, 2023 October 30, 2027
NCT03994601 Active, not recruiting Phase 1/Phase 2 An Investigational Immunotherapy Study of BMS-986288 Alone and in Combination With Nivolumab in Advanced Solid Cancers September 6, 2019 May 14, 2025
NCT03568058 Active, not recruiting Phase 1 Personalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers July 26, 2018 December 2025
NCT05103358 Active, not recruiting Phase 2 Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1) February 15, 2022 December 31, 2025
NCT03775525 Active, not recruiting Phase 1 Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or in Combination With Capecitabine in Metastatic Hormone Receptor Positive Breast Cancer March 1, 2019 December 2023
NCT03352531 Active, not recruiting Phase 1 Study of the Safety, Pharmacokinetics, and Antitumor Activity of AK105 in Subjects With Advanced Solid Tumors December 22, 2017 October 2023
NCT03446040 Active, not recruiting Phase 1/Phase 2 An Investigational Immunotherapy Study of BMS-986258 Alone and in Combination With Nivolumab in Participants With Solid Cancers That Are Advanced or Have Spread March 8, 2018 April 15, 2025
NCT03674567 Active, not recruiting Phase 1/Phase 2 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab September 25, 2018 January 2025
NCT05047042 Active, not recruiting N/A A Feasibility Study of a Virtual Rehabilitation and Physical Activity Program for People With Advanced Cancer January 17, 2022 October 2024
NCT05025085 Active, not recruiting Phase 1 A Study Investigating AGEN1777 in Participants With Advanced Solid Tumors October 4, 2021 September 30, 2025
NCT04991480 Active, not recruiting Phase 1 A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors September 13, 2021 August 2025
NCT03440437 Active, not recruiting Phase 1/Phase 2 A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies April 16, 2018 June 2024
NCT03307785 Active, not recruiting Phase 1 Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042 October 12, 2017 August 30, 2024
NCT01087554 Active, not recruiting Phase 1 Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer March 2010 August 18, 2026
NCT03833479 Active, not recruiting Phase 2 TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation (ATOMICC) June 28, 2019 December 2025
NCT05840510 Active, not recruiting Phase 1/Phase 2 Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19) August 7, 2023 June 30, 2026
NCT03375437 Active, not recruiting N/A RNASARC - Molecular Screening Program of Soft Tissue Sarcomas With Complex Genomic Profile to Detect NTRK1/2/3, ROS1 or ALK Gene Fusions. February 15, 2018 January 15, 2025
NCT04435444 Active, not recruiting N/A Meaning-Centered Intervention for Muslim Patients Who Are Being Treated for Advanced Cancer June 15, 2020 June 2024
NCT03829501 Active, not recruiting Phase 1/Phase 2 Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer January 28, 2019 August 5, 2024
NCT03425565 Active, not recruiting Phase 2 A Study of Pembrolizumab in Patients With Advanced Gynaecological Clear Cell Cancer February 18, 2019 September 2024
NCT03510104 Active, not recruiting Phase 1 Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors May 22, 2018 July 2024
NCT04945928 Active, not recruiting N/A Safety and Feasibility of Surgery After Conversion Therapy for Locally Advanced and Advanced NSCLC August 27, 2021 June 5, 2026
NCT03909334 Active, not recruiting Phase 2 Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) July 25, 2019 June 2024
NCT03526679 Active, not recruiting Phase 1/Phase 2 Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma July 12, 2018 June 30, 2023
NCT04339062 Active, not recruiting Phase 1/Phase 2 Cemiplimab in AlloSCT/SOT Recipients With CSCC November 3, 2020 January 1, 2025
NCT02455505 Active, not recruiting Identifying Family Members in Need of Support While Caregiving and After Loss May 2015 May 2027
NCT04864418 Active, not recruiting Phase 1 AST-021p Study in Advanced Solid Tumors June 9, 2021 November 2023
NCT03013218 Active, not recruiting Phase 1 A Study of Evorpacept (ALX148) in Patients With Advanced Solid Tumors and Lymphoma (ASPEN-01) February 3, 2017 December 1, 2024
NCT04330664 Active, not recruiting Phase 1/Phase 2 Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2) April 22, 2020 December 24, 2024
NCT04065984 Active, not recruiting N/A Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES) April 14, 2019 March 1, 2026
NCT03029403 Active, not recruiting Phase 2 Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer February 12, 2018 February 12, 2025
NCT04310345 Active, not recruiting N/A Impact of Human-Animal Interactions on Children With Life-Threatening Conditions and Their Parents March 31, 2021 February 2025
NCT04012749 Active, not recruiting N/A UC Health Care Planning Study October 25, 2019 September 15, 2024
NCT03042156 Active, not recruiting Immunotherapy And Palliative Radiotherapy Combined In Patients With Advanced Malignancy January 10, 2017 June 2024
NCT01187199 Active, not recruiting Phase 1 Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer August 19, 2010 April 30, 2026
NCT04861987 Active, not recruiting Phase 1 A Study of the Safety and PK of PCS6422 (Eniluracil) With Capecitabine in Patients With Advanced, Refractory GI Tract Tumors June 18, 2021 August 10, 2024
NCT04837196 Active, not recruiting Phase 1/Phase 2 Study of ASP7517 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors Expressing WT1 Antigen December 6, 2021 June 30, 2024
NCT04121676 Active, not recruiting Phase 1 Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer September 26, 2019 June 2027
NCT00761618 Active, not recruiting Phase 2 Intrapleural Catheter Daily Versus Three Times a Week Drainage August 22, 2008 August 31, 2024
NCT04270864 Active, not recruiting Phase 1 Intratumoral Tilsotolimod, a TLR-9 Agonist, Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers April 10, 2020 February 2026
NCT03369223 Active, not recruiting Phase 1/Phase 2 A Study of BMS-986249 Alone and in Combination With Nivolumab in Advanced Solid Tumors December 6, 2017 September 19, 2024
NCT05298592 Active, not recruiting Phase 1 A Study of BMS-986406 as Monotherapy and Combination Therapies in Participants With Advanced Tumors March 31, 2022 July 15, 2024
NCT06107868 Active, not recruiting Phase 1 Phase 1 Study of RP-6306 With Carboplatin and Paclitaxel in TP53 Ovarian and Uterine Cancer March 20, 2024 December 4, 2026
NCT02711553 Active, not recruiting Phase 2 A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer May 19, 2016 December 31, 2025
NCT03763032 Active, not recruiting N/A Psychosocial Intervention in Latino Patients With Advanced Cancer January 23, 2018 July 2024
NCT00488072 Active, not recruiting Phase 2 Effects of Mirtazapine on Appetite in Advanced Cancer Patients September 20, 2006 December 31, 2025
NCT03195699 Active, not recruiting Phase 1 Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers November 15, 2017 December 1, 2024
NCT03177291 Active, not recruiting Phase 1 Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC September 26, 2017 June 2024
NCT03667716 Active, not recruiting Phase 1 COM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors. September 6, 2018 May 31, 2024
NCT05162443 Approved for marketing Expanded Access of Adagrasib (MRTX849) in Patients With Advanced Solid Tumors Who Have a KRAS G12C Mutation
NCT00710736 Completed Phase 1 A Study of ARRY-334543 and Capecitabine in Patients With Advanced Cancer June 2008 April 2011
NCT00736372 Completed Phase 1 A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer June 2008 August 2009
NCT00741403 Completed Phase 1 A Open Label Phase I/II Clinical Trial to Evaluate CPI-613 in Patients With Advanced Malignancies August 2008 December 2016
NCT00761644 Completed Phase 1 Doxil, Bevacizumab and Temsirolimus Trial August 21, 2008 March 28, 2019
NCT00770731 Completed Phase 1 Study of Temsirolimus, Topotecan, and Bortezomib September 2008 November 2012
NCT00785226 Completed Phase 1/Phase 2 RDEA119 and Sorafenib Combination Dose Escalation Study November 2008 April 2012
NCT00798252 Completed Phase 1 Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers March 2009 May 2015
NCT00833326 Completed Phase 1 A Study of ARRY-334543 and Docetaxel in Patients With Advanced Cancer January 2009 July 2010
NCT00862524 Completed Phase 1/Phase 2 A Study of ARRY-334543 and Gemcitabine in Patients With Advanced Cancer and Pancreatic Cancer March 2009 February 2011
NCT00878267 Completed Patient-Reported Outcomes (PRO)-Based Palliative and Hospice Care Practice: A Qualitative Study March 2009 September 2011
NCT00881569 Completed Phase 1 Extended Use Protocol for Participants With Cancer to Receive Continued Treatment With CS-7017 March 2009 September 2011
NCT00895128 Completed Phase 1 Study of Erlotinib in Combination With Dasatinib April 2009
NCT00895687 Completed Phase 1 Study of Erlotinib in Combination With Bortezomib April 2009
NCT00907738 Completed Phase 2 A Continuation Clinical Trial of Oral Vorinostat (MK-0683) in Advanced Cancers (MK-0683-007) August 2005 June 2010
NCT00933361 Completed Phase 1/Phase 2 Individual Dose-escalated Bi-daily Subcutaneously (sc) Ghrelin in Cancer Cachexia: a Phase I/II Study June 2009 December 2011
NCT00940381 Completed Phase 1 Sirolimus and Cetuximab in Advanced Malignancies July 2009 May 2014
NCT00949390 Completed Complementary and Alternative Medicine Usage Among Participants Enrolled in Phase I Oncology Clinical Trials July 2009 April 2016
NCT00951262 Completed Phase 4 Intervention Study on Life Review Among Advanced Cancer Patients in Fuzhou, China February 2009 June 2010
NCT00951574 Completed Phase 3 Prevention of Venous and Arterial Thromboembolism, in Cancer Patients Undergoing Chemotherapy, With a Low Molecular Weight Heparin (Nadroparin Calcium) October 2003 July 2008
NCT00955812 Completed Phase 1 STAT3 Inhibitor for Solid Tumors June 2009 November 2012
NCT00965341 Completed Phase 3 Testosterone Replacement for Fatigue in Male Hypogonadic Advanced Cancer Patients September 2009 September 2012
NCT00970125 Completed N/A Using Video Images to Improve Advance Care Planning in Patients With Cancer August 2009 June 2011
NCT00980122 Completed Aggressiveness of Care at the End of Life in Cancer Patients March 2008
NCT00980239 Completed Phase 1 HAI Irinotecan + IV Bevacizumab, Bevacizumab & Oxaliplatin or Bevacizumab & Cetuximab in Advanced Cancers Metastatic to Liver September 2009 August 2015
NCT00994578 Completed N/A Intervention Study of Communication in Oncologist-Patient Encounters November 2010 April 2014
NCT01015222 Completed Phase 1 Dasatinib, Bevacizumab, Paclitaxel in Patients With Advanced Malignancies November 2009 May 27, 2021
NCT01048008 Completed Phase 1 Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer September 2010 November 2013
NCT01054313 Completed Phase 1 Docetaxel and Sirolimus in Patients With Advanced Malignancies January 2010 October 2014
NCT01072266 Completed Phase 1 A Dose-escalation Study in Subjects With Advanced Malignancies January 2010 January 2013
NCT01081301 Completed Phase 2 Living With Hope Program for Rural Women Caregivers January 2009 March 2012
NCT01113476 Completed Phase 1 Nab-paclitaxel, Gemcitabine, and Bevacizumab in Advanced Malignancies April 27, 2010 August 12, 2022
NCT01115790 Completed Phase 1 A Phase 1 Study in Participants With Advanced Cancer February 2010 January 2016
NCT01143779 Completed Phase 1 FLT-PET as an Imaging Biomarker With Temsirolimus, Topotecan, and Bortezomib June 2010 December 27, 2021
NCT01152203 Completed Phase 1 Bendamustine and Bevacizumab for Advanced Cancers June 2010 May 2014
NCT01158404 Completed Phase 1 Notch Inhibitor in Advanced Cancer July 2010 August 2012
NCT01197170 Completed Phase 1 Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance September 7, 2010 January 13, 2021
NCT05910541 Completed N/A The Efficacy of Multisession Mindful Breathing in Symptom Reduction Among Patients With Advanced Cancers January 2, 2020 March 31, 2020
NCT01212107 Completed Phase 1 A Phase 1 Study of LY2874455 in Participants With Advanced Cancer December 2010 February 2015
NCT01214629 Completed Phase 1 A Study for Participants With Advanced Cancer July 2007 May 2012
NCT01214642 Completed Phase 1 A Dose-Escalation Study for Patients With Advanced Cancer May 2008 June 2012
NCT01226485 Completed Phase 1 A Study in Advanced Cancer September 2010 October 2017
NCT01241929 Completed N/A Using Videos in Advance Care Planning for Patients With Advanced Cancer April 2009 April 2012
NCT01245621 Completed N/A Study of Palliative Care Intervention for Advanced Cancer Patients and Their Caregivers -Educate Nurture Advise Before Life Ends (ENABLE III) October 2010 September 2013
NCT01262651 Completed Phase 3 Sativex® for Relieving Persistent Pain in Participants With Advanced Cancer November 25, 2010 July 2, 2015
NCT01287520 Completed Phase 1 A Study of LY2090314 in Patients With Advanced or Metastatic Cancer November 2007 April 2011
NCT01287546 Completed Phase 1 A Study of LY2875358 in Participants With Advanced Cancer April 13, 2010 October 26, 2016
NCT01295632 Completed Phase 1 Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049) February 2011 August 2015
NCT01296568 Completed Phase 1 C14 Study in Oncology Patients With Advanced and/or Metastatic Solid Tumors February 2011 February 2012
NCT01337089 Completed Phase 3 Long Term Safety of Sativex Oromucosal Spray (Sativex®; Nabiximols) as Adjunctive Therapy in Patients With Uncontrolled Persistent Chronic Cancer Related Pain January 19, 2011 January 27, 2016
NCT01339871 Completed Phase 1 Study of Pazopanib and Vorinostat in Patients With Advanced Malignancies April 20, 2011 June 7, 2017
NCT01358110 Completed N/A Emergency Department-Based Palliative Care for Advanced Cancer Patients May 2011 January 2015
NCT01361607 Completed Phase 3 Sativex® for Relieving Persistent Pain in Patients With Advanced Cancer May 27, 2011 November 24, 2014
NCT01367795 Completed Surgical Procedures for Advanced Tumor Disease. A Prospective Study Evaluating Quality of Life July 2010 October 2014
NCT01393990 Completed Phase 1 A Study of LY2228820 in Participants With Advanced Cancer September 4, 2008 December 14, 2013
NCT01394016 Completed Phase 1 A Phase 1 Study of LY2835219 In Participants With Advanced Cancer December 7, 2009 April 12, 2022
NCT01417065 Completed Early Phase 1 Temsirolimus In Phase 0 August 2010
NCT01423903 Completed Phase 1 Phase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer February 2010 April 2013
NCT01424566 Completed Phase 3 A Two-Part Study of Sativex® Oromucosal Spray for Relieving Uncontrolled Persistent Pain in Patients With Advanced Cancer June 29, 2012 December 28, 2015
NCT01443390 Completed An Ancillary Pilot Trial Using Whole Genome Sequencing In Patients With Advance Refractory Cancer September 2011 March 2013
NCT01444157 Completed Phase 3 Family and Coping Oriented Palliative Homecare Nursing Aimed at Advanced Cancer Patients October 2011 April 2014
NCT01462383 Completed The Role of the EKG in Anticancer Drug Development January 2011 November 2011
NCT01463982 Completed Phase 1 Phase I of OratecanTM in Combination With Capecitabine in Patients With Advanced Solid Malignancies December 2010 December 2013
NCT01505153 Completed Phase 1 Phase I Intratumoral Pbi-shRNA STMN1 LP in Advanced and/or Metastatic Cancer February 2012 April 13, 2017
NCT01524224 Completed Phase 1 A Dose-Escalation Study in Participants With Advanced Cancer January 2008 January 2016
NCT01538537 Completed Phase 1 Safety of ON 01910.Na as a 3-day Infusion in Patients With Advanced Cancer August 2006 January 2012
NCT01538563 Completed Phase 1 Safety of 24-Hour Infusion of ON 01910.Na in Patients With Advanced Cancer June 2006 November 2011
NCT01539733 Completed N/A Early Recognition and Optimal Treatment of Delirium in Patients With Advanced Cancer March 2010 April 2017
NCT01543841 Completed Laboratory Testing for Tie-2 Expressing Monocytes (TEMs) in Blood August 2012 January 2014
NCT00085787 Completed Phase 1 A Study of ARRY-142886 in Patients With Advanced Cancer June 2004 February 2007
NCT01567345 Completed N/A Intrathecal Morphine Administration Using Implantable Pump With Continuous or Programmable Flow January 14, 2009 October 2010
NCT01576406 Completed Phase 1 Hepatic Impairment Study For Crizotinib In Advanced Cancer Patients July 2012 June 2016
NCT01583777 Completed Phase 1 Phase I Mass Balance, PK and Safety Study of 14C-Labeled Belinostat in Patients With Advanced Cancer September 2013 April 2015
NCT01596140 Completed Phase 1 Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer December 18, 2012 June 1, 2020
NCT01644968 Completed Phase 1 Phase 1 Study of Anti-OX40 in Patients With Advanced Cancer November 2003 April 2017
NCT01655225 Completed Phase 1 A Study of LY3023414 in Participants With Advanced Cancer July 31, 2012 February 2, 2022
NCT01660360 Completed Phase 1 Phase I Trial of Tanibirumab in Advanced or Metastatic Cancer November 2011 September 2013
NCT05364905 Completed Patients Characteristics, Treatment Pattern & Outcomes of Patients With Advanced, Recurrent or Metastatic Endometrial Carcinoma May 9, 2022 November 22, 2022
NCT01693991 Completed Phase 1 Randomized Controlled Trial of the Meaning-Making Intervention (MMi) October 2012 December 2013
NCT05315427 Completed Impact of Music Therapy on Pain in Patients Treated for Advanced Cancer May 2, 2022 January 5, 2023
NCT01833923 Completed Phase 1 A Phase I Study of Anlotinib on Tolerance and Pharmacokinetics May 2011 October 2015
NCT01863485 Completed Phase 1 Phase 1 Study of CM082 (X-82) Tablets in Advanced Cancer Patients in China May 2013 May 2016
NCT01864681 Completed Phase 2 Combination of Metformin With Gefitinib to Treat NSCLC May 2013 June 4, 2018
NCT01901237 Completed N/A Yoga for Adolescent and Young Adult Non-Curative Cancer Patients September 2013 June 13, 2017
NCT01954316 Completed Phase 1 A Study of CFI-400945 Fumarate in Patients With Advanced Cancer March 2014 July 22, 2021
NCT01976143 Completed Phase 1 A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety February 2014 September 2016
NCT01976910 Completed Phase 1 Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer" September 2010 October 2013
NCT01977638 Completed Phase 1 Phase 1 Trial of CXD101 in Patients With Advanced Cancer February 14, 2014 October 14, 2022
NCT05137782 Completed N/A The Science of the Art of Palliative Care January 3, 2023 November 30, 2023
NCT02014909 Completed Phase 1 A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced Tumors January 2014 June 5, 2017
NCT02082210 Completed Phase 1/Phase 2 A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer March 7, 2014 January 24, 2018
NCT00147225 Completed Phase 1/Phase 2 AMG 531 in Patients With Advanced Malignancy Receiving Treatment With Carboplatin August 2005 March 2013
NCT05103488 Completed N/A Comprehensive Palliative Care for Cancer Patients in Vietnam May 7, 2020 April 30, 2021
NCT02193633 Completed Phase 1 A Phase I Trial of the Combination of AZD2014 and Weekly Paclitaxel. April 26, 2013 November 15, 2017
NCT02219711 Completed Phase 1 Phase 1/1b Study of MGCD516 in Patients With Advanced Cancer August 2014 April 27, 2022
NCT02245204 Completed Phase 1 Phase I Studies of Chlorogenic Acid for Injection for Tolerance and Pharmacokinetic of Advanced Cancers September 2014 October 2016
NCT02332317 Completed N/A Early, Integrated, Specialized Palliative Rehabilitation December 2014 June 2018
NCT02338622 Completed Phase 1 Trial of Olaparib in Combination With AZD5363 (ComPAKT) March 31, 2014 March 21, 2017
NCT04975256 Completed Phase 1 Adagrasib in Combination With BI 1701963 in Patients With Cancer (KRYSTAL 14) August 12, 2021 November 15, 2022
NCT02357108 Completed N/A Message: Study of Patients' Perception of Physician's Compassion May 2013 August 2015
NCT02383212 Completed Phase 1 Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies February 2, 2015 November 18, 2019
NCT02383368 Completed Phase 1 A Dose Escalation and Expansion Study of ASP4132 to Subjects With Advanced Refractory Tumors and Lymphoma March 23, 2015 April 27, 2018
NCT02407990 Completed Phase 1 Study of the Safety, Pharmacokinetics and Antitumor Activities of BGB-A317 in Participants With Advanced Tumors June 2, 2015 August 12, 2020
NCT02418624 Completed Phase 1 Phase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced Cancer May 2015 January 2019
NCT02430467 Completed N/A Caregiver-Guided Pain Management Training in Palliative Care July 2015 October 4, 2019
NCT04869267 Completed N/A Acceptance and Commitment Therapy in Patients With Advanced Lung Cancer July 1, 2021 January 7, 2022
NCT02470715 Completed Identifying Molecular Drivers of Cancer April 2014 May 22, 2018
NCT02507544 Completed Phase 1 A Safety and Pharmacokinetic Study of TRX-818 Administered Orally to Patients With Advanced Cancer September 2015 May 20, 2019
NCT02529553 Completed Phase 1 A Study of LY3076226 in Participants With Advanced or Metastatic Cancer September 2015 March 28, 2018
NCT02583932 Completed Phase 3 Randomized Controlled Trial of the Meaning-Making Intervention (MMi) In Newly Diagnosed Advanced Cancer October 2015 August 2020
NCT02642016 Completed Phase 1 A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid Tumors December 2015 June 4, 2019
NCT02655289 Completed N/A Transcutaneous Electrical Nerve Stimulation (TENS) for Advanced Cancer Pain Patients February 2016 March 2018
NCT02658890 Completed Phase 1/Phase 2 An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread April 14, 2016 October 26, 2021
NCT04772690 Completed N/A Balance, Activity and Quality of Life May 1, 2021 December 24, 2021
NCT04738305 Completed N/A Feasibility of Dignity Therapy Intervention on Cancer Patients in Charge to an Hospital Palliative Care Unit. June 2016 December 2017
NCT02703298 Completed Phase 1 Safety and Pharmacokinetic Study of TRX-818 in Asian Solid Tumor Patients March 25, 2016 May 3, 2018
NCT02712229 Completed N/A A Primary Palliative Care Intervention for Patients With Advanced Cancer July 27, 2016 October 15, 2020
NCT02737475 Completed Phase 1/Phase 2 An Investigational Immuno-Therapy Study of Experimental Medication BMS-986178 by Itself or in Combination With Nivolumab and/or Ipilimumab in Participants With Solid Cancers That Are Advanced or Have Spread June 17, 2016 November 2, 2020
NCT02745769 Completed Phase 1 A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents October 21, 2016 January 22, 2019
NCT04678921 Completed Phase 1 Study of TJ210001 Administered in Subjects With Relapsed or Refractory Advanced Solid Tumors December 17, 2020 November 21, 2022
NCT04640714 Completed N/A Care Transition Intervention for Patients With Cancer January 7, 2021 July 14, 2021
NCT02777710 Completed Phase 1 Evaluation of Safety and Activity of an Anti-PDL1 Antibody (DURVALUMAB) Combined With CSF-1R TKI (PEXIDARTINIB) in Patients With Metastatic/Advanced Pancreatic or Colorectal Cancers June 2016 December 2019
NCT02778126 Completed Phase 1 A Study of Prexasertib (LY2606368) in Participants With Advanced Cancer September 22, 2016 July 27, 2017
NCT04626349 Completed N/A International Study to Evaluate Two Programs of Support for Patients With Advanced Cancer and Their Families February 24, 2021 November 30, 2023
NCT04606940 Completed Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN) October 19, 2020 October 12, 2021
NCT04480008 Completed N/A Resilient Living Program for Patients With Advanced Cancer and Their Caregivers July 15, 2020 December 27, 2021
NCT02825563 Completed Phase 1 A Phase I Study of Anlotinib on Pharmacokinetics to Assess the Effect of High Fat Diet in Advanced Cancer Patients June 2016 August 15, 2018
NCT02841124 Completed N/A Decision to Limit or Withdraw Specific Therapies for Advanced Cancer and Hematological Malignancies. January 2011 August 2011
NCT02857270 Completed Phase 1 A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer September 29, 2016 October 24, 2022
NCT02860780 Completed Phase 1 A Study of Prexasertib (LY2606368) in Combination With Ralimetinib in Participants With Advanced or Metastatic Cancer August 10, 2016 May 15, 2017
NCT02884726 Completed Phase 1 Phase 1 Study of Mesothelin-ADC October 14, 2016 September 6, 2017
NCT04471818 Completed Phase 1/Phase 2 Ketamine or Placebo in Patients With Major Depression and Advanced Cancer September 19, 2019 July 30, 2023
NCT02919696 Completed Phase 1 A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers August 7, 2017 September 3, 2019
NCT02930876 Completed Phase 2 Feasibility of Home vs. Hospital Based Resistance Training for Advanced Cancer Patients July 2016 February 8, 2017
NCT02944136 Completed N/A Collaborative Care Intervention for Cancer Caregivers December 2016 March 7, 2023
NCT02957565 Completed N/A Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During an Outpatient Palliative Care Visit November 3, 2016 January 2, 2020
NCT02966509 Completed N/A Engagement of Patients With Advanced Cancer August 2013 December 2016
NCT02980289 Completed DAnish Nausea Study In Advanced Cancer-Epidemiology: A Danish Multicenter Trial to Investigate the Prevalence and Treatment of Nausea and/or Vomiting in Patients With Advanced Cancer. February 2016 July 1, 2018
NCT02992171 Completed N/A Primary Palliative Care for Patients With Advanced Hematologic Malignancies May 2, 2017 March 19, 2020
NCT04386057 Completed Phase 2 LY3214996 +/- HCQ in Pancreatic Cancer May 27, 2020 February 5, 2024
NCT02996110 Completed Phase 2 A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma February 2, 2017 November 23, 2021
NCT04336124 Completed Phase 1 Safety and Pharmacokinetic Study of CVM-1118 Extended-Release in Advanced Cancer Patients May 25, 2020 April 8, 2022
NCT04335253 Completed Phase 1 First-In-Human Study of EOS884448 in Participants With Advanced Cancers. February 18, 2020 April 7, 2022
NCT03027284 Completed Phase 1 A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancer February 3, 2017 March 17, 2020
NCT03040102 Completed N/A Randomized Study of a Hospice Video Educational Tool for Patients With Advanced Cancer and Their Caregivers March 9, 2017 February 1, 2019
NCT03094780 Completed N/A Quality of Life Intervention for Patients Receiving Radiation Therapy for Advanced Cancer Treatment and Their Caregivers July 2016 February 21, 2019
NCT03098550 Completed Phase 1/Phase 2 A Study to Test the Safety and Effectiveness of Nivolumab Combined With Daratumumab in Patients With Pancreatic, Non-Small Cell Lung or Triple Negative Breast Cancers, That Have Advanced or Have Spread June 15, 2017 July 6, 2020
NCT04303091 Completed N/A The Feasibility of a Physical Activity Intervention for Advanced Multiple Myeloma Patients March 2, 2018 December 20, 2018
NCT03104699 Completed Phase 1/Phase 2 Study of AGEN2034 in Advanced Tumors and Cervical Cancer April 11, 2017 June 15, 2022
NCT04257617 Completed Phase 1 A Trial of ZL-1201 in Subjects With Advanced Cancer May 11, 2020 January 19, 2023
NCT04254926 Completed N/A Impact of a Resource-based Life Review Intervention on Advanced Cancer Patients April 6, 2019 August 18, 2021
NCT00278902 Completed Phase 1 A Study of ARRY-334543 in Patients With Advanced Cancer January 2006 June 2009
NCT03137121 Completed Phase 2/Phase 3 Olanzapine for the Treatment of Chronic Nausea and/or Vomiting in Advanced Cancer Patients July 12, 2017 September 15, 2020
NCT03140137 Completed Immune Checkpoint Inhibitors and Pre-existing Autoimmune Diseases January 21, 2017 January 4, 2018
NCT03168035 Completed Phase 1 Study of NC-4016 in Patients With Advanced Solid Tumors or Lymphoma November 2013 April 2017
NCT03181854 Completed N/A Randomized Controlled Trial of Integrated Early Palliative Care September 8, 2017 June 30, 2019
NCT03192943 Completed Phase 1 A Study of BMS-986205 Given in Combination With Nivolumab in Patients With Advanced Tumors June 23, 2017 December 11, 2018
NCT02666183 Completed N/A Online Information and Support for Distance Caregivers April 6, 2016 April 16, 2020
NCT03765099 Completed N/A Animal-Assisted Interactions in Children With Life-Threatening Conditions and Their Parents February 21, 2019 December 31, 2022
NCT03780816 Completed Variation in Cancer Centers' End-of-Life Quality July 5, 2019 July 15, 2021
NCT00421135 Completed Phase 1 A Protocol for the Safety and Tolerance of Intravenous Isophosphoramide Mustard (IPM) in Patients With Advanced Cancer February 2006 October 2007
NCT03792750 Completed Phase 1/Phase 2 A Study of BMS-986205 Alone and in Combination With Nivolumab in Chinese Patients With Advanced Malignant Solid Tumors December 31, 2018 December 18, 2020
NCT00423410 Completed Phase 1 A Safety Study of EPC2407, A Anti-Cancer Drug With Vascular Disrupting Activity: In Patients With Advanced Cancer December 2006 September 2009
NCT03833817 Completed N/A Patient-caregiver Communication Intervention for Prognostic Understanding September 20, 2020 January 18, 2022
NCT03823313 Completed N/A Feasibility, Acceptability and Preliminary Effects of the Spiritual Care Assessment and Intervention December 10, 2018 August 28, 2019
NCT00423722 Completed N/A Parenteral Hydration in Advanced Cancer Patients January 9, 2007 May 2013
NCT00424099 Completed Phase 2/Phase 3 Methylphenidate and a Nursing Telephone Intervention for Fatigue January 9, 2007 November 22, 2021
NCT00429234 Completed Phase 1 Gemcitabine and Dasatinib in Advanced Solid Tumors January 2007 February 2013
NCT00438620 Completed The Feasibility of Physical Activity in Advanced Cancer Patients October 2006
NCT00450541 Completed Fatigue Experience in Cancer Patients March 2007 April 2010
NCT00477243 Completed Locus of Control and Spirituality in Palliative Care Patients June 3, 2004 August 11, 2017
NCT00489593 Completed Phase 1 Olanzapine in Patients With Advanced Cancer and Weight Loss October 2006 December 2013
NCT00493714 Completed Delirium Recall in Advanced Cancer Patients July 2005 December 2007
NCT00505544 Completed Measuring Sleep Disturbance Among Cancer Patients August 2005 July 11, 2022
NCT00507754 Completed Latent Tuberculosis Infection in Cancer Patients June 2007 May 2011
NCT00507962 Completed Phase 1 Cisplatin HAI Study in Patients With Advanced Cancer and Dominant Liver Involvement March 2005 May 2011
NCT00508326 Completed Phase 1 Paclitaxel Administered by HAI to Patients With Advanced Cancer and Dominant Liver Involvement October 2005 October 2010
NCT00512291 Completed N/A Subcutaneous Olanzapine for Hyperactive or Mixed Delirium June 2005 August 2009
NCT00513162 Completed Phase 1 Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases July 2007
NCT00106626 Completed Phase 1 Suberoylanilide Hydroxamic Acid in Advanced Solid Tumors August 2005 December 2007
NCT00518739 Completed Phase 1 MK2461 in Patients With Advanced Cancer (2461-001)(COMPLETED) February 2007 December 2008
NCT00530907 Completed Phase 1 Valproic Acid and Bevacizumab in Patients With Advanced Cancer June 2007 November 2013
NCT00543153 Completed The Exceptional Patient in Cancer Care August 2007 August 2010
NCT00543504 Completed Phase 1 Bevacizumab in Multiple Phase I Combinations October 10, 2007 April 29, 2020
NCT00551850 Completed Phase 1 A Safety Study of an Oral EGFR Inhibitor, AV-412, Administered Three Times Weekly in Advanced Solid Tumor Patients October 2007 May 2010
NCT00559182 Completed Phase 1 A Study of MK-8033 in Patients With Advanced Solid Tumors (MK-8033-001) December 5, 2007 July 9, 2010
NCT00581880 Completed Measuring Hope and Hopelessness in Cancer January 2005 January 2009
NCT06323135 Completed Nutrition Assessment in Advanced Cancer Patients September 17, 2019 September 11, 2023
NCT00591890 Completed Phase 1 Phase IB Study of Indibulin Using Positron-Emission Tomography (PET) Scans October 2007 March 2009
NCT06118125 Completed Delay to Diagnosis in Digestive Cancerology by the General Practitioner Related to Covid-19 Pandemic Confinement June 1, 2019 September 1, 2022
NCT00608803 Completed Phase 1 Phase 1 Study of ZIO-201-T in Combination With Doxorubicin in Solid Tumors January 2008 January 2009
NCT00610194 Completed Phase 1 Phase 1 Dose-escalation PK/PD Trial in Advanced Cancer Patients November 28, 2007 August 1, 2012
NCT00610493 Completed Phase 1 Bevacizumab and Temsirolimus in Patients With Advanced Malignancy January 25, 2008 November 28, 2017
NCT00621725 Completed Phase 1 Phase 1 PK Study of Cediranib in Single and Multiple Doses in Hepatically Impaired Patients With Solid Tumours January 2008 January 2014
NCT00625638 Completed N/A Interactive Voice Response System in Advanced Cancer Patients January 28, 2008 December 2, 2022
NCT00629200 Completed Phase 1 Sodium Stibogluconate With Interferon Alpha-2b for Patients With Advanced Malignancies September 13, 2006 February 10, 2010
NCT00629473 Completed Phase 1 Phase 1 Clinical Trial of NPI-0052 in Patients With Advanced Malignancies July 2007 April 2013
NCT00634257 Completed Spirituality/Religiosity in Patients and Caregivers February 22, 2008 February 10, 2022
NCT00637702 Completed Phase 1 A Study of ARRY-334543 in Patients With Advanced Cancer February 2008 October 2012
NCT00656461 Completed Phase 1 Phase 1 Study of MKC-1 in Patients With Advanced Cancer March 2008 November 2009
NCT00658671 Completed Phase 1 A Dose-Escalation Study of ENMD-2076 Administered Orally to Patients With Advanced Cancer April 2008 June 2012
NCT00664170 Completed Phase 1 A Bioequivalence Study of Docetaxel for Injectable Emulsion (ANX-514) in Patients With Advanced Cancer April 2008 April 2009
NCT00667485 Completed Phase 1 Rapamycin Plus Bevacizumab in Advanced Cancers April 2008 May 2012
NCT00682994 Completed N/A Patient and Family Decision Making in the Palliative Care Setting March 2008 August 2012
NCT00687349 Completed Phase 3 Improving Clinician Communication Skills (ICCS) April 2007 March 2013
NCT00687505 Completed Phase 1 Safety Study of FP-1039 To Treat Cancer July 2008 June 2011
NCT00688038 Completed Phase 4 Correlation of MR Thermal Imaging to Actual Size of Ablation During Laser Ablation Therapy May 13, 2008 September 12, 2017
NCT00697632 Completed Phase 1 Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies June 2008 January 2019
NCT00698841 Completed Phase 2 Study to Evaluate the Effect of Cetuximab on Corrected QT (QTc) Interval Changes in Patients With Advanced Malignancies From Solid Tumors February 2009 February 2010
NCT00707135 Completed Phase 1 Rapamycin in Advanced Cancers June 2005 December 2008
NCT00708591 Completed Phase 1 Study of Rapamycin Plus Ketoconazole in Advanced Cancers October 2004 December 2008
NCT00708773 Completed Phase 1 Genotype-Directed Dose-Escalation Study of Irinotecan in Patients With Advanced Solid Tumors February 2006 August 2016
NCT00709176 Completed N/A Outcomes of Triaged Family Care in Advanced Cancer June 2005 May 2010
NCT03475251 Completed Phase 1 A Study of CS1003 in Subjects With Advanced Solid Tumors May 9, 2018 May 31, 2021
NCT03507166 Completed Phase 2 A Phase II Study of RC48-ADC in Subjects With HER2 Positive Metastatic or Unresectable Urothelial Cancer December 28, 2017 October 29, 2018
NCT03980041 Completed Phase 2 Study to Evaluate the Efficacy/Safety of IPI-549 in Combination With Nivolumab in Patients With Advanced Urothelial Carcinoma (MARIO-275) September 25, 2019 November 15, 2022
NCT03532997 Completed N/A Extra Layer Of Support October 1, 2018 January 7, 2020
NCT03536728 Completed Phase 1 Oral AMXT 1501 Dicaprate in Combination With DFMO June 12, 2018 April 21, 2023
NCT03979118 Completed Exercise Prescription in Patients With Bone Metastases October 15, 2019 January 31, 2022
NCT03954067 Completed Phase 1 A Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors August 8, 2019 April 19, 2024
NCT03565757 Completed N/A Stress Management and Resilience Training (SMART) Intervention for Family Caregivers of Individuals With Advanced Cancer July 19, 2018 December 31, 2020
NCT03579628 Completed Phase 1 AsiDNA (a DNA Repair Inhibitor) Administered IntraVenously in Advanced Solid Tumors April 5, 2018 February 20, 2022
NCT03941262 Completed Phase 1 Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy July 15, 2019 February 17, 2023
NCT00408226 Completed Phase 1/Phase 2 Safety Study of MKC-1 Combined With Pemetrexed to Treat Advanced Cancer and Non-Small Cell Lung Cancer October 2006 January 2012
NCT03610243 Completed N/A Patient-centered Self-administered Acupressure for Fatigue Management in Chinese Advanced Cancer Patients August 7, 2018 May 31, 2019
NCT03936959 Completed Phase 1 A Study of LY3434172, a PD-1 and PD-L1 Bispecific Antibody, in Advanced Cancer May 24, 2019 April 29, 2021
NCT03661632 Completed Phase 1 An Investigational Immunotherapy Study of BMS-986310 Administered Alone and in Combination With Nivolumab in Patients With Advanced Solid Tumors September 11, 2018 December 29, 2020
NCT03668847 Completed Phase 2 DM-CHOC-PEN for Brain Tumors in AYA Subjects January 1, 2019 September 30, 2021
NCT03851146 Completed Phase 1 A Study of Anti-Lewis Y Chimeric Antigen Receptor-T Cells (LeY-CAR-T) in Patients With Solid Tumours November 24, 2016 April 1, 2022
NCT03714958 Completed Phase 1 Trametinib + HDM201 in CRC Patients With RAS/RAF Mutant and TP53 Wild-type Advanced/Metastatic Colorectal Cancer Mutant and TP53 Wild-type December 20, 2018 September 12, 2023
NCT03717298 Completed Phase 2 Evaluation of Ocoxin-Viusid® in Advanced Pancreatic Adenocarcinoma October 30, 2018 January 20, 2023
NCT03837132 Completed Early Palliative Care on Quality of Life of Patients With Advanced Pancreas Cancer October 15, 2018 June 30, 2021
NCT03730142 Completed Phase 1 A Study of WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma October 25, 2018 July 25, 2020
NCT03745807 Completed Phase 1 An Investigational Study of NKTR-214 Combined With Nivolumab in Japanese Participants With Advanced Solid Tumors April 9, 2019 December 18, 2019
NCT03751995 Completed N/A POEM (Practice of Embracing Each Moment) Study (Delivery Science) October 31, 2018 April 29, 2020
NCT03203876 Completed Phase 1 A Safety Study of Lirilumab in Combination With Nivolumab or in Combination With Nivolumab and Ipilimumab in Advanced and/or Metastatic Solid Tumors July 14, 2017 August 6, 2020
NCT03207360 Completed N/A Pain Coping Skills and Meaning-Centered Intervention November 17, 2017 February 11, 2020
NCT04200963 Completed Phase 1 A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma December 18, 2019 July 18, 2023
NCT04193319 Completed Phase 1 Effect of Fluconazole on PK of Fluzoparib in Healthy Male Subjects July 19, 2019 September 12, 2019
NCT04149704 Completed N/A Videos for Advance Care Planning in Young Adults December 13, 2019 May 5, 2022
NCT03252678 Completed N/A Efficacy of Self-education Program for Advanced Care Planning(RCT) August 17, 2017 February 28, 2018
NCT03254173 Completed Phase 2/Phase 3 Mirtazapine for Treatment of Cancer Associated Anorexia-cachexia March 26, 2018 October 17, 2019
NCT04148937 Completed Phase 1 A Study of the CD73 Inhibitor LY3475070 Alone or in Combination With Pembrolizumab in Participants With Advanced Cancer January 16, 2020 June 20, 2022
NCT03260712 Completed Phase 2 Pembrolizumab in Biliary Tract Cancer January 7, 2020 August 31, 2023
NCT03285633 Completed N/A Telephone-Based Mindfulness CBT for Patients in Community Settings With Advanced Cancer January 3, 2018 September 8, 2018
NCT03312842 Completed Phase 1 A Phase Ia/Ib Study of CS1001 in Subjects With Advanced Solid Tumors October 19, 2017 February 16, 2022
NCT03316157 Completed N/A Exercise and Nutritional Rehabilitation in Patients With Cancer January 30, 2018 July 3, 2019
NCT03323489 Completed N/A Celiac Plexus Radio-Surgery for Pain Management January 1, 2018 May 1, 2022
NCT04071262 Completed Phase 1 A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer December 20, 2019 August 30, 2021
NCT03325985 Completed N/A Emergency Medicine Palliative Care Access March 28, 2018 August 24, 2023
NCT03335540 Completed Phase 1 An Adaptive Study to Match Patients With Solid Tumors to Various Immunotherapy Combinations Based Upon a Broad Biomarker Assessment May 7, 2018 August 25, 2021
NCT03356223 Completed Phase 2 Evaluation of ABEMACICLIB Monotherapy in Patients With Locally Advanced/Metastatic Head and Neck Cancer After Failure of Platinum and Cetuximab or Anti-EGFR-based Therapy and Harboring an Homozygous Deletion of CDKN2A, and/or an Amplification of CCND1 and/or of CDK6 February 5, 2018 December 5, 2022
NCT03371004 Completed Phase 1 DM-CHOC-PEN Plus Radiation for Brain Tumors February 5, 2016 October 1, 2022
NCT00385476 Completed Cancer Patients' Medication Knowledge in the Emergency Center August 2005 February 2009
NCT03408314 Completed N/A The PediQUEST Response Intervention Study March 1, 2018 September 14, 2022
NCT03411200 Completed N/A Patient Activation Through Counseling, Exercise and Mobilization April 4, 2018 July 1, 2020
NCT03432247 Completed N/A Pain Management Support Study for Patients With Advanced Cancer February 1, 2018 December 31, 2021
NCT05407844 Enrolling by invitation N/A Community Health Worker Based Intervention to Improve Palliative Care November 2, 2023 September 1, 2027
NCT04289155 No longer available Individual Patient Compassionate Use of GX-I7
NCT02889445 No longer available A Phase I Trial of DM-CHOC-PEN in Adolescent and Young Adult (AYA) Subjects With Advanced Cancers
NCT06090513 Not yet recruiting Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients October 18, 2023 October 18, 2025
NCT06117709 Not yet recruiting N/A Integrated Smartphone Technology to Alleviate Malignant Pain (I-STAMP) Testing August 2024 April 30, 2025
NCT06346197 Not yet recruiting Phase 3 Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas May 15, 2024 May 15, 2028
NCT05749549 Not yet recruiting Phase 1/Phase 2 Phase I/IIa Study of BR1733 in Subjects With Advanced Cancers April 2023 May 2026
NCT06363201 Not yet recruiting N/A Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours April 28, 2024 December 15, 2025
NCT05885984 Not yet recruiting N/A Acceptance and Commitment Therapy on Fatigue Interference in Patients With Advanced Lung Cancer and Caregiver Burden (ACT) July 2023 January 2024
NCT05917990 Not yet recruiting N/A Dyadic Text-Messaging Micro-Intervention May 2024 July 2026
NCT05988697 Not yet recruiting Evaluate the Efficacy and Safety of Aspirin in Combination With Trametinib and Dabrafenib November 1, 2023 April 1, 2027
NCT06001749 Not yet recruiting Phase 2 Psilocybin in Cancer Pain Study July 2024 December 31, 2026
NCT06190886 Not yet recruiting Phase 1 A First-in-human (FIH), Multicenter, Open-Label, Phase I Study of PTX-912 in Patients With Locally Advanced/Metastatic Solid Tumors April 27, 2024 July 24, 2026
NCT06416085 Not yet recruiting Phase 2 Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer June 1, 2024 June 15, 2026
NCT06093425 Not yet recruiting Phase 3 Combination of TST001, Nivolumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma October 31, 2023 January 31, 2026
NCT06067087 Not yet recruiting Prognostic Understanding in ESC (ProgESC Study) November 15, 2023 October 31, 2024
NCT04599608 Not yet recruiting Prediction of Drug Response Using an Ex Vivo Organ Culture (EVOC) on Fresh Human Tumour Samples From Metastatic Patients February 2021 January 2026
NCT06082128 Not yet recruiting N/A FOCUSau: A Dyadic Digital Health Intervention to Improve the Wellbeing of People With Advanced Cancer and Their Carers December 2023 August 2025
NCT06420609 Not yet recruiting N/A Efficacy of a Proactive Approach to Death Thoughts in People With Advanced Cancer May 14, 2024 December 21, 2025
NCT06457997 Not yet recruiting Phase 1 A Study of PHN-010 in Patients With Advanced Solid Tumors July 2024 July 2027
NCT06389097 Not yet recruiting SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization May 2024 May 2029
NCT05735496 Not yet recruiting Phase 1 Clinical Trial of the TQB2102 Injection in Patients With Advanced Cancers February 2023 October 2024
NCT05408507 Recruiting N/A Care Planning Framework in Advanced Cancer (ABC123) February 15, 2022 December 2026
NCT00515060 Recruiting Psychophysical Studies of Cancer Therapy Pain January 23, 2001 April 30, 2025
NCT02112188 Recruiting Meaning-Centered Counseling for Chinese Patients Who Are Being Treated for Advanced Cancer April 2014 February 15, 2025
NCT02628067 Recruiting Phase 2 Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) December 18, 2015 May 4, 2027
NCT03129139 Recruiting Phase 1 A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors October 10, 2017 December 1, 2024
NCT03175224 Recruiting Phase 2 APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors September 27, 2017 November 30, 2026
NCT03391479 Recruiting Phase 2 A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy August 15, 2018 December 31, 2024
NCT03503149 Recruiting Molecular Tumor Board at the Center for Personalized Medicine Tübingen March 1, 2018 March 1, 2028
NCT03605771 Recruiting Descriptive Observational Study on the Characteristics of Advanced and Metastatic Melanoma in Spain August 7, 2018 December 2024
NCT03785249 Recruiting Phase 1/Phase 2 Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1 December 26, 2018 January 2026
NCT03810339 Recruiting Phase 2 Toripalimab as Monotherapy in Participants With POLE or POLD-1 Mutated and Non-MSI-H Advanced Solid Tumors January 15, 2019 January 15, 2024
NCT03829254 Recruiting Phase 1/Phase 2 A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma June 17, 2019 June 2024
NCT03832855 Recruiting Phase 1 Assessing the Immunogenicity of pING-hHER3FL July 13, 2020 September 1, 2025
NCT03860272 Recruiting Phase 1 Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer April 1, 2019 December 2026
NCT03875781 Recruiting Phase 3 Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer June 5, 2019 December 5, 2026
NCT04095208 Recruiting Phase 2 Combination of Nivolumab Plus Relatlimab in Patients With Advanced or Metastatic Soft-tissue Sarcoma: a Proof-of-concept Randomized Phase II Study February 27, 2020 December 2025
NCT04146298 Recruiting Phase 1/Phase 2 Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer October 21, 2021 March 2025
NCT04204434 Recruiting Biomarkers For Immune Checkpoint Inhibitors November 29, 2016 September 2024
NCT04237805 Recruiting Phase 1/Phase 2 A Phase I/II Clinical Study of SAF-189s in Non-small Cell Lung Cancer (NSCLC) Patients November 14, 2016 March 31, 2026
NCT04321954 Recruiting Phase 2 Lenvatinib in Locally Advanced Invasive Thyroid Cancer March 9, 2021 March 2025
NCT04354246 Recruiting Phase 1 COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies March 31, 2020 March 30, 2025
NCT04396821 Recruiting Phase 1/Phase 2 A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors May 28, 2020 December 31, 2024
NCT04406662 Recruiting Routine Evaluation of People Living With Cancer July 15, 2020 August 8, 2029
NCT04407013 Recruiting N/A Enhanced Supportive Care for Advanced Cancer Patients: Evaluation of Standardized Care Pathway June 23, 2020 February 2024
NCT04419532 Recruiting Phase 1 A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors October 9, 2020 December 31, 2024
NCT04467593 Recruiting N/A Safety Study of Whole Body Hyperthermia for Advanced Cancer July 28, 2021 December 2024
NCT04495296 Recruiting Phase 1/Phase 2 A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors August 13, 2020 November 1, 2024
NCT04495790 Recruiting AIMS Cancer Outcomes Study May 18, 2020 December 31, 2030
NCT04590885 Recruiting N/A Coping Together: Couple-based Interventions for Cancer October 20, 2020 December 31, 2024
NCT04606238 Recruiting N/A Decision Aid to Support Advanced Cancer Patients October 1, 2019 April 1, 2023
NCT04648202 Recruiting Phase 1 FS120 Phase 1/1b Study in Patients With Advanced Malignancies November 18, 2020 March 1, 2026
NCT04648254 Recruiting Phase 1 Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor in Patients With Advanced Solid Tumor November 18, 2020 February 28, 2025
NCT04657068 Recruiting Phase 1/Phase 2 A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors December 13, 2020 June 2025
NCT04672603 Recruiting N/A Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal Cancer April 8, 2021 May 1, 2025
NCT04740424 Recruiting Phase 1 FS222 First in Human Study in Patients With Advanced Malignancies December 14, 2020 May 2025
NCT04757155 Recruiting N/A Phase II RCT of an Internet-adaptation of Managing Cancer and Living Meaningfully (iCALM) October 13, 2021 January 31, 2025
NCT04823377 Recruiting N/A Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer. September 24, 2021 September 20, 2026
NCT04833023 Recruiting Phase 3 HALO Trial: Haloperidol vs Olanzapine in Hyperactive Delirium in Palliative Care Patients; A Multi-Centre, Randomised-Controlled Trial May 18, 2022 December 2024
NCT04840004 Recruiting Phase 2 Efficacy and Safety of PVT-1 Treatment in Patients With Advanced Non-Small Cell Lung Cancer March 10, 2021 December 31, 2025
NCT04900818 Recruiting Phase 1 Study of TJ033721 in Subjects With Advanced or Metastatic Solid Tumors June 29, 2021 December 2024
NCT04936568 Recruiting N/A Palliative Care Referral System (PCRS) for Cancer Patients With Advanced Disease July 14, 2021 December 2023
NCT05004116 Recruiting Phase 1/Phase 2 A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor Cancer August 9, 2021 August 2028
NCT05028218 Recruiting Phase 1 A Clinical Study of TQB3824 in Subjects With Advanced Cancer August 31, 2021 December 2024
NCT05045040 Recruiting N/A Empathetic Communication Facilitation Program for Early Initiation of End-of-life Discussions September 6, 2021 September 2023
NCT05060432 Recruiting Phase 1/Phase 2 Study of EOS-448 With Standard of Care and/or Investigational Therapies in Participants With Advanced Solid Tumors September 6, 2021 January 2025
NCT05076552 Recruiting Phase 1 A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer February 17, 2023 July 2025
NCT05076760 Recruiting Phase 1 MEM-288 Oncolytic Virus Alone and in Combination With Nivolumab in Solid Tumors Including Non-Small Cell Lung Cancer February 23, 2022 November 2026
NCT05082259 Recruiting Phase 1 ASTEROID: A Trial of ASTX660 in Combination With Pembrolizumab March 2, 2022 March 16, 2026
NCT05113199 Recruiting N/A Virtual Dignity Therapy for Palliative Care Patients With Advanced Cancer November 18, 2021 October 31, 2025
NCT05159245 Recruiting Phase 2 The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs December 10, 2021 November 25, 2026
NCT05166694 Recruiting N/A Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions November 30, 2022 November 1, 2025
NCT05192512 Recruiting Phase 1 Clinical Trial of the TQB2928 Injection in Patients With Advanced Cancers January 24, 2022 January 2025
NCT05204147 Recruiting Phase 1 Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic Cancers June 2, 2022 August 7, 2025
NCT05257590 Recruiting Phase 2 CVM-1118 in Combination With Nivolumab for Unresectable Advanced Hepatocellular Carcinoma May 23, 2022 March 31, 2026
NCT05270213 Recruiting Phase 1 Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors July 11, 2022 October 2025
NCT05276310 Recruiting Phase 1 A Study of IMC-002 in Patients With Advanced Cancer Failed to Standard Therapy May 10, 2022 December 31, 2026
NCT05315999 Recruiting Phase 2 Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care May 3, 2022 May 2025
NCT05320588 Recruiting Phase 1/Phase 2 A Study in Patients With Advanced Cancers March 25, 2022 April 2027
NCT05375994 Recruiting Phase 1/Phase 2 Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients August 1, 2022 January 1, 2025
NCT05394103 Recruiting Phase 1/Phase 2 Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors August 30, 2022 August 30, 2026
NCT05394675 Recruiting Phase 1 A Study of DS-9606a in Patients With Advanced Solid Tumors May 31, 2022 February 19, 2026
NCT05398484 Recruiting Phase 2/Phase 3 Psilocybin Therapy in Advanced Cancer May 24, 2023 January 1, 2027
NCT05403801 Recruiting N/A STAMP+CBT mHealth for Cancer Pain July 1, 2022 December 31, 2023
NCT05420519 Recruiting Phase 1 Clinical Study of CD70-targeted CAR-T Therapy for Advanced/Advanced Renal Cancer December 31, 2021 December 31, 2024
NCT05426330 Recruiting Advanced Cancer Patients' and Their Primary Caregivers' Willingness to Communicate About Advance Care Planning (ACP) October 4, 2021 October 4, 2024
NCT05450419 Recruiting N/A The Role of Vitamin D3 Supplementation in Advanced Cancer Patients With Pain July 1, 2021 June 30, 2025
NCT05498597 Recruiting Phase 1 AMT-151 in Patients With Selected Advanced Solid Tumours January 25, 2023 October 30, 2024
NCT05500508 Recruiting Phase 1/Phase 2 Oral AMXT 1501 Dicaprate in Combination With IV DFMO November 29, 2022 September 30, 2024
NCT05557045 Recruiting Phase 1 A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815 October 10, 2022 April 1, 2028
NCT05584111 Recruiting Phase 1 Oral Administration of STC-15 in Subjects With Advanced Malignancies November 15, 2022 May 30, 2025
NCT05605509 Recruiting Phase 2 RP-6306 in Patients With Advanced Cancer May 24, 2023 June 2025
NCT05714553 Recruiting Phase 1/Phase 2 NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours March 8, 2023 January 2025
NCT05735080 Recruiting Phase 1/Phase 2 Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer March 28, 2023 June 2026
NCT05782361 Recruiting Phase 1 POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC May 3, 2023 February 1, 2028
NCT05802420 Recruiting N/A The Value of Molecular Residual Disease Monitoring Based on ctDNA in Advanced or Metastatic Pancreatic Cancer February 1, 2023 February 1, 2025
NCT05812677 Recruiting Early Phase 1 A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Cervical and Endometrial Cancer February 6, 2023 February 6, 2026
NCT05853575 Recruiting Phase 2 Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21) February 1, 2024 September 2025
NCT05859074 Recruiting Phase 1 A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer May 4, 2023 May 4, 2028
NCT05864144 Recruiting Phase 1/Phase 2 A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors May 31, 2023 June 2027
NCT05877430 Recruiting Phase 1/Phase 2 Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer September 11, 2023 October 2027
NCT05884788 Recruiting Study of the Life Stories of Patients Making a Request for Euthanasia, in the Context of Advanced Cancer. June 1, 2023 March 2024
NCT05891171 Recruiting Phase 1 Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers October 13, 2023 August 2025
NCT05894421 Recruiting Phase 1 TQB2223 Injection in Combination With Penpulimab in Patients With Advanced Cancers June 6, 2023 January 2026
NCT05971277 Recruiting Home And Locally Observed - Tracking (HALO-Trak) January 30, 2023 April 1, 2026
NCT06010875 Recruiting Phase 1 A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors November 30, 2023 September 30, 2026
NCT06081517 Recruiting Evaluating Disparities in Precision Oncology January 26, 2024 July 2029
NCT06092580 Recruiting Phase 1 Phase 1 Study of AWT020 in Advanced Cancer September 15, 2023 September 15, 2025
NCT06120075 Recruiting Phase 1 A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies January 19, 2024 November 2026
NCT06174987 Recruiting Phase 3 A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s) January 5, 2024 August 3, 2026
NCT06188624 Recruiting Phase 1 Clinical Trial of TQB2922 for Injection in Patients With Advanced Cancers February 1, 2024 December 2025
NCT06200155 Recruiting Phase 2 Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy April 16, 2024 December 31, 2026
NCT06210776 Recruiting A Study to Assess the Effectiveness of Trastuzumab Deruxtecan in Chinese Breast Cancer Patients (REFRESH) January 15, 2024 March 1, 2028
NCT06215950 Recruiting Phase 1 A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Gynecologic Cancer January 10, 2024 December 31, 2027
NCT06227728 Recruiting Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer. March 22, 2024 December 31, 2026
NCT06228326 Recruiting Phase 1 A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs April 17, 2024 February 2027
NCT06229158 Recruiting Assessment of the Quality and Sexual Health Needs of Patients With Advanced-stage Cancer February 5, 2024 September 13, 2024
NCT06239467 Recruiting Phase 1 First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer March 1, 2024 August 1, 2027
NCT06240767 Recruiting Phase 1 Clinical Study on the Treatment of Advanced Recurrent Tumors With Anticancer Mouse Characteristic Human Neutrophils November 1, 2023 December 31, 2025
NCT06242470 Recruiting Phase 1 A Study of MGC026 in Participants With Advanced Solid Tumors March 6, 2024 October 2028
NCT06285500 Recruiting Umbrella Study for Single Patient Treatments in Oncology February 1, 2024 February 1, 2029
NCT06302140 Recruiting Phase 1 A Mass Balance Study of [14C]-Nanatinostat and Relative Bioavailability Study of Nanatinostat in Patients With Advanced Cancers February 28, 2024 October 2025
NCT06338683 Recruiting Phase 3 Survival With Olanzapine in Patients With Locally Advanced or Metastatic Upper Gastrointestinal and Lung Cancer March 20, 2024 March 20, 2028
NCT06362369 Recruiting Phase 1/Phase 2 A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy May 20, 2024 December 31, 2028
NCT06405490 Recruiting Phase 2 NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC April 17, 2024 December 30, 2026
NCT06440005 Recruiting Phase 1 A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors May 2024 May 2027
NCT02130492 Suspended Phase 1/Phase 2 A Pilot Study Treatment of Malignant Tumors Using [18F] Fluorodeoxyglucose (FDG) May 2014 July 2025
NCT04001010 Suspended Phase 3 Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia July 2022 December 2023
NCT00607711 Suspended Phase 1 Study of Oral Palifosfamide Tris in Solid Tumors March 2008 November 2009
NCT03722186 Suspended Phase 1 Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of SHR-1603 in Subjects With Advanced Malignancies November 13, 2018 October 2021
NCT03120130 Suspended Phase 1 Study of Amblyomin-X in Advanced Solid Tumor February 15, 2021 May 22, 2022
NCT02318901 Terminated Phase 1/Phase 2 Pembrolizumab and Monoclonal Antibody Therapy in Advanced Cancer October 2014 August 2018
NCT00684242 Terminated Phase 2 Lenalidomide (Revlimid) for the Treatment of Refractory Cancer Pain May 2008 October 2011
NCT04250597 Terminated Phase 1 Study of GNX102 in Patients With Advanced Solid Tumors July 29, 2020 July 26, 2023
NCT01545921 Terminated N/A Cancer End Of Life Evaluation November 11, 2011 June 6, 2019
NCT01185548 Terminated Phase 1 A Drug Interaction Study of Tasisulam in Patients With Advanced Cancer or Lymphoma July 2010 December 2010
NCT03110107 Terminated Phase 1/Phase 2 First-In-Human Study of Monoclonal Antibody BMS-986218 by Itself and in Combination With Nivolumab in Participants With Advanced Solid Tumors May 4, 2017 April 4, 2024
NCT00606879 Terminated Phase 1 Safety Study of SGX523, a Small Molecule Met Inhibitor, to Treat Solid Tumors January 2008 June 2009
NCT01209832 Terminated Phase 1 A Tasisulam and Midazolam Drug Interaction Study in Cancer Patients September 2010 January 2011
NCT05525455 Terminated Phase 1/Phase 2 TT-816 as Monotherapy or in Combination With a PD-1 Inhibitor in Patients With Advanced Cancers (SEABEAM) (MK3475-E88) August 29, 2022 September 7, 2023
NCT00895024 Terminated Caregiver Assessments of the Quality of Home Hospice Care April 2009 September 28, 2020
NCT03582618 Terminated Phase 2 CVM-1118 and Sorafenib Combination in Subjects With Advanced Hepatocellular Carcinoma July 12, 2018 December 30, 2022
NCT02580045 Terminated Pharmacokinetics of Systemic Anti-Cancer Therapies in the Cerebrospinal Fluid (CSF) of Patients With Advanced Cancer April 1, 2016 February 22, 2018
NCT00504985 Terminated Fatigue in Emergency Center Patients August 2005 April 2008
NCT03525392 Terminated Phase 1 Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1. May 3, 2018 April 28, 2021
NCT00729833 Terminated Phase 1 Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid Tumors September 2008 April 2013
NCT03002831 Terminated Phase 2 Autologous Cytokine-induced Killer Cells Combined Chemotherapy in Advanced Pancreatic Cancer November 2016 October 2019
NCT02554812 Terminated Phase 1/Phase 2 A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley) November 9, 2015 March 23, 2023
NCT00634010 Terminated Phase 3 Morphine Versus Methadone As First Line Strong Opioid for Cancer Pain February 2008 January 2015
NCT03444753 Terminated Phase 1 An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed April 5, 2018 February 14, 2022
NCT02992977 Terminated Phase 1 Safety and Tolerability Study of AutoSynVax™ Vaccine in Subjects With Advanced Cancer January 2017 December 2019
NCT00529230 Terminated Prevalence of Secondary Hypogonadism in Male Patients on Chronic Opioid Therapy for Cancer-Related Pain Syndromes December 11, 2001 February 19, 2004
NCT00430014 Terminated Phase 1 Study of Atiprimod Treatment for Patients With Advanced Cancer March 2005 February 2012
NCT01347866 Terminated Phase 1 Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer October 2011 December 2015
NCT00625742 Terminated N/A Multimodal Treatment Strategy for Cancer Cachexia February 2008 June 2014
NCT01887041 Terminated Phase 4 Quality of Life After Biliodigestive Anastomosis (BDA) or Stents to Treat Biliary Obstruction in Pancreas Cancer January 2010 December 2015
NCT02136342 Terminated Phase 1 Phase 1 Trial of Chlorogenic Acid in Patients With Advanced Cancer May 2014
NCT04441099 Terminated Phase 1/Phase 2 NBE-002 in Patients With Advanced Solid Tumors June 19, 2020 August 14, 2023
NCT00352664 Terminated Phase 3 The Effect of Donepezil on Sedation and Other Symptoms November 2003 July 2007
NCT00385775 Terminated Phase 1 Study of XIAP Antisense for Advanced Cancers June 2006 November 2008
NCT02805660 Terminated Phase 1/Phase 2 Phase 1/2 Study of Mocetinostat and Durvalumab in Patients With Advanced Solid Tumors and NSCLC June 1, 2016 December 20, 2019
NCT00607399 Terminated Phase 1 Safety Study of SGX523, a Small Molecule Met Inhibitor, to Treat Solid Tumors January 2008 June 2009
NCT02750514 Terminated Phase 2 An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer May 9, 2016 January 29, 2020
NCT01688791 Terminated Phase 1 A Study of MK-8109 (Vintafolide) Given Alone or With Chemotherapy in Participants With Advanced Cancers (MK-8109-001) December 2012 September 2014
NCT02801097 Terminated Phase 1 RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer (PAYLOAD) August 30, 2016 December 9, 2019
NCT00704821 Terminated Phase 1 PTC299 for Treatment of Advanced Cancer July 3, 2008 February 24, 2012
NCT01394003 Terminated Phase 1 A Study of LY2584702 in Participants With Advanced Cancer November 2008 April 2011
NCT05128539 Terminated Phase 1 A Study Explore JS001+JS002 in Patients With Advanced Cancer February 10, 2022 November 10, 2023
NCT02423954 Terminated Phase 1/Phase 2 Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus) April 2015 November 1, 2017
NCT02341625 Terminated Phase 1/Phase 2 A Study of BMS-986148 in Patients With Select Advanced Solid Tumors June 19, 2015 May 7, 2020
NCT02331251 Terminated Phase 1/Phase 2 Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus) December 2014 January 2018
NCT03258541 Terminated N/A Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy January 15, 2017 May 2020
NCT01929941 Terminated Phase 1 An Open-Label Study of a Novel JAK-inhibitor, INCB047986, Given in Patients With Advanced Malignancies September 2013 August 2014
NCT03690154 Terminated Phase 1 A Phase 1 Study to Evaluate FN-1501 Monotherapy in Patients With Advanced Solid Tumors and R/R AML July 23, 2018 February 11, 2022
NCT02671955 Terminated Phase 1 A Study of Safety, Pharmacokinetics, Pharmacodynamics of JNJ-61610588 in Participants With Advanced Cancer January 2016 July 2017
NCT00832520 Terminated Phase 2 Phase II Study of Remeron for Cancer Patients Losing More Than 10% of Their Body Weight November 2008 June 2011
NCT05154630 Terminated Phase 1/Phase 2 Study on Tolerability and Pharmacokinetics of TQB2858 Injection in Subjects With Advanced Malignant Tumors January 14, 2022 June 30, 2023
NCT01744249 Unknown status Phase 2/Phase 3 Sandostatin LAR and Axitinib vs Pbo in Pnts With Advanced Well-differentiated Non-pancreatic Neuroendocrine Carcinomas November 2011 October 2021
NCT04942756 Unknown status N/A GLYPALCARE STUDY - Multicenter, Randomized Study for Evaluating Continuous Glucose Monitoring (CGM) by Using FreeStyle Libre 2 (FSL2) for Preventing Hyperglycemia/Hypoglycemia Crisis in Advanced Oncological Patients. June 30, 2021 June 30, 2022
NCT00792896 Unknown status N/A Intervention Toward Truth-Telling and Advanced Directives in the Patient With Advanced or Metastatic Disease May 2008
NCT01527331 Unknown status N/A A ProspectiveTrial Using Video Images in Advance Care Planning in Hospitalized Seriously Ill Patients With Advanced Cancer June 2011
NCT05136937 Unknown status Phase 1 A Clinical Study of Intratumoral Administration of RT-01 in Patients With Advanced Solid Tumors November 1, 2021 June 1, 2023
NCT01983956 Unknown status N/A A Structured Early Palliative Care Intervention for Patients With Advanced Cancer - a Randomized Controlled Trial With a Nested Qualitative Study (SENS Trial) December 23, 2013 April 25, 2020
NCT03811379 Unknown status Phase 2 Toripalimab as Monotherapy for Patients With Small Cell Carcinoma of Esophagus Who Failed Chemotherapy November 21, 2018 December 30, 2021
NCT05142345 Unknown status N/A Care Transition Intervention for Hospitalized Patients With Advanced Cancer December 15, 2021 December 2023
NCT03900442 Unknown status Phase 1 Phase 1 Study of PTX-100 in Patients With Advanced Malignancies With PTCL Expansion Cohort September 1, 2019 April 30, 2023
NCT03922204 Unknown status Phase 1 A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies May 8, 2019 December 2022
NCT03645200 Unknown status Phase 1 Treatment of Carrying TP53 Harmful Mutations July 1, 2019 June 1, 2020
NCT03554889 Unknown status Phase 1 Immunotherapy of Advanced Cancer Using a Combination Nimotuzumab and NK Cells August 1, 2018 November 27, 2019
NCT03546426 Unknown status Phase 1 Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients With PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapies December 12, 2019 January 2024
NCT03986515 Unknown status Phase 2 Apatinib Plus SHR1210 in Advanced Mucosal Melanoma June 4, 2019 May 31, 2022
NCT03518970 Unknown status N/A Uncertainty in Illness in Palliative Care: an Intervention for Family Caregivers August 1, 2018 March 1, 2019
NCT04042597 Unknown status Phase 2 Anlotinib Hydrochloride Versus Imatinib Mesylate in Locally Advanced, Unresectable or Metastatic Chordoma July 18, 2019 December 31, 2021
NCT03387436 Unknown status N/A The "Hand-in-Hand Study": Improvement of Quality of Life in Palliative Cancer Patients Through Collaborative Advance Care Planning December 4, 2017 September 1, 2020
NCT03325218 Unknown status Survival Expectations and Hope Among Cancer Patients at End-of-Life April 1, 2018 August 31, 2021
NCT04089306 Unknown status Integration of Palliative Care in an Oncology and Hematology Unit October 1, 2019 May 2020
NCT04110223 Unknown status Validation Studies of Biomarkers for Precision Radiation Oncology in Locally Advanced Solid Tumors October 8, 2018 October 8, 2021
NCT04121039 Unknown status Phase 2 Study of the Apatinib Combine With POF Versus POF in Gastric Cancer December 2019 December 2023
NCT03261011 Unknown status Phase 1 Study of the Safety, Pharmacokinetics, and Antitumor Activity of AK104 in Subjects With Advanced Solid Tumors October 3, 2017 September 2020
NCT04124666 Unknown status Phase 1/Phase 2 Clinical Study of Granulocyte Infusion for Advanced Cancer December 1, 2019 September 30, 2022
NCT04141397 Unknown status Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer Care July 1, 2014 December 31, 2021
NCT03243643 Unknown status Phase 1 Tolerability, Safety, Pharmacokinetics and Efficacy of HS-10241 Single Agent or Combined With Apatinib in Patients With Advanced Solid Tumors August 8, 2017 December 2019
NCT03221400 Unknown status Phase 1/Phase 2 PEN-866 in Patients With Advanced Solid Malignancies August 29, 2017 June 2023
NCT03219775 Unknown status Phase 2 Tailored ImmunoTherapy Approach With Nivolumab in Subjects With Metastatic or Advanced Transitional Cell Carcinoma July 6, 2017 February 18, 2023
NCT01361529 Unknown status Phase 1 Safety Study of FLP Injection to Treat Tumor Patients June 2009 July 2011
NCT04257786 Unknown status N/A Primary Cyto-reductive Surgery Vs Neo-adjuvant Chemotherapy (NAC) in Epithelial Ovarian Cancer March 1, 2020 April 1, 2022
NCT03099330 Unknown status Phase 1 A Phase I Study of TQ-B3139 on Tolerance and Pharmacokinetics July 19, 2017 December 2018
NCT04308356 Unknown status Do Patients Want to Engage in Discussions Dedicated to Anticipating (DDA) Their Preferences of Care in the Event of Worsening Health Status? June 3, 2020 June 2022
NCT03030001 Unknown status Phase 1/Phase 2 PD-1 Antibody Expressing CAR T Cells for Mesothelin Positive Advanced Malignancies February 15, 2017 February 1, 2019
NCT04317651 Unknown status Crizotinib in ALK Rearranged Non-small-cell Lung Cancer May 16, 2019 June 2022
NCT04318808 Unknown status N/A Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer March 1, 2020 August 2022
NCT00214838 Unknown status Phase 1/Phase 2 An Open-Label Study of the Safety and Efficacy of Atiprimod Treatment for Patients With Advanced Cancer March 2005 March 2007
NCT03019276 Unknown status Phase 1 A Phase I Study of TQ-B3101 on Tolerance and Pharmacokinetics July 5, 2017 December 2018
NCT03008109 Unknown status Phase 3 Endostar Plus EGFR-TKI(Epidermal Growth Factor Receptor-Tyrosine-Kinase Inhibitor) as a Treatment of EGFR Mutation-positive NSCLC February 2017 November 2018
NCT02996838 Unknown status Phase 1 A Phase I Study of TQ-B3234 on Tolerance and Pharmacokinetics May 11, 2017 December 2020
NCT04376931 Unknown status Phase 1/Phase 2 A Prospective Dose Finding Study of Iscador Infusion December 1, 2020 July 1, 2023
NCT04385654 Unknown status Phase 2 Toripalimab Combined With Axitinib as Neoadjuvant Therapy for Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma June 2020 June 2022
NCT04398875 Unknown status N/A Adjunctive Effect of Acupuncture for Advanced Cancer Patients With Palliative Care: a Three-arm Randomized Trial September 1, 2020 August 31, 2023
NCT02944864 Unknown status Phase 1 A Phase I Study of TQ-B3395 on Tolerance and Pharmacokinetics August 13, 2017 October 2018
NCT00591422 Unknown status Phase 1 Phase I Study of Oral Darinaparsin (ZIO-101-C)in Advanced Solid Tumors and Non-Hodgkin's Lymphomas August 2007 June 2013
NCT02797795 Unknown status Phase 1 A Phase 1, Open-Label, Dose-Escalation Study of NEV801, Administered to Patients With Advanced Cancers December 2016 December 2021
NCT02779699 Unknown status Phase 1 A Study of AL2846 on Tolerance and Pharmacokinetics May 2016 October 2020
NCT01313247 Unknown status Phase 4 Paracetamol for Cancer Pain April 2011 December 2012
NCT02684318 Unknown status Phase 1/Phase 2 Study to Evaluate PM01183 in Combination With Olaparib in Advanced Solid Tumors July 2015 October 2019
NCT01611961 Unknown status Phase 1 Docetaxel Lipid Microsphere (DT-LM) for Injection in Chemotherapy Patients August 2012 December 2014
NCT05438342 Unknown status N/A An Expanded Clinical Study of Triple Therapy for Refractory Solid Tumors That Failed First-line Treatment for Recurrence and Metastasis November 1, 2021 October 31, 2023
NCT04859777 Unknown status Phase 1 A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors April 13, 2021 March 2023
NCT02469883 Unknown status Phase 1 A Study of Sinotecean on Tolerance and Pharmacokinetics March 2015 December 2016
NCT04943627 Withdrawn Phase 3 Balstilimab Versus Investigator Choice Chemotherapy in Patients With Recurrent Cervical Cancer (BRAVA) August 2, 2021 October 22, 2021
NCT02432612 Withdrawn Phase 1 A Study to Assess the Pharmacokinetic (PK) Properties of Sativex® in Patients With Advanced Cancer October 2015 October 2016
NCT03122249 Withdrawn N/A Oncology Associated Symptoms & Individualized Strategies March 10, 2017 September 20, 2019
NCT04158700 Withdrawn Phase 1/Phase 2 A Study of LY3200882 and Pembrolizumab in Participants With Advanced Cancer December 5, 2019 May 11, 2023
NCT03671720 Withdrawn Early Phase 1 Personalized Vaccine Generated by Autologous Dendritic Cells Pulsed With Autologous Whole Tumor Cell Lysate Treat Advanced Solid Tumor Patients With High Tumor Mutation Burden September 11, 2018 December 30, 2022
NCT03904342 Withdrawn N/A Sophie Pilot Implementation and Assessment January 2021 December 2021
NCT04584775 Withdrawn N/A Implementing Acupuncture and Chinese Herbal Medicine Into Palliative Care February 2021 July 2022
NCT02915172 Withdrawn Phase 1 Lenvatinib and Capecitabine in Patients With Advanced Malignancies December 2016
NCT02261051 Withdrawn Symptom Management, Quality of Life and Satisfaction With Care for Advanced Stage Cancers - Control Arm October 2014 September 2015
NCT05262842 Withdrawn Phase 1 JS001+IMP4297 in Patients With Advanced Cancer March 29, 2022 June 6, 2024
NCT03104335 Withdrawn Phase 2 Apatinib for Advanced Soft Tissue Sarcoma Patients: a Phase 2, Multicenter Trial April 1, 2017 March 1, 2020
NCT02747797 Withdrawn Phase 2 Lucitanib (E3810) in Patients With Advanced Cancer and FGFR, VEGFR, or PDGFR Pathway Aberrations April 2017 April 2022