diabetic retinopathy

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Information
Disease name
diabetic retinopathy
Disease ID
DOID:8947
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03922932 Active, not recruiting WF and PR OCTA in Diabetic Retinopathy August 30, 2017 December 2025
NCT03694145 Active, not recruiting Predicting Diabetic Retinopathy From Risk Factor Data and Digital Retinal Images October 25, 2018 July 31, 2024
NCT04505566 Active, not recruiting Phase 1 INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study November 9, 2020 December 2025
NCT02330042 Active, not recruiting OCT Biomarkers for Diabetic Retinopathy September 2014 December 2024
NCT04503551 Active, not recruiting Phase 3 A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm August 10, 2020 May 7, 2024
NCT02119689 Active, not recruiting Vascular Reparative Mechanism in Diabetes October 30, 2011 October 30, 2024
NCT05808699 Active, not recruiting Camera Qualification Study March 3, 2023 November 30, 2024
NCT04708145 Active, not recruiting Phase 4 Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial June 1, 2021 September 2024
NCT05581225 Active, not recruiting Prediction of Progression of Retinal Ischemia in Diabetes December 2, 2022 October 31, 2028
NCT06150495 Active, not recruiting Glycemic Control and Retinal Microvascular Changes January 1, 2019 December 31, 2025
NCT05112445 Active, not recruiting Retinal Ischemia Characterization in Diabetes - "RICHARD" May 3, 2022 August 14, 2024
NCT05007262 Active, not recruiting Phase 2 Tangningtongluo Tablet in the Treatment of Non-proliferative Diabetic Retinopathy August 31, 2021 December 31, 2023
NCT04782128 Active, not recruiting Phase 2 Evaluation of RC28-E Injection in Diabetic Retinopathy May 25, 2021 July 2024
NCT04328207 Active, not recruiting N/A Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits November 18, 2020 September 29, 2024
NCT04271709 Active, not recruiting N/A Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT) September 30, 2019 September 29, 2024
NCT01736059 Active, not recruiting Phase 1 Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy July 2012 October 2025
NCT00119535 Completed N/A Study to Evaluate the Effectiveness of a Program Developed to Improve Eye Care for Veterans With Diabetes August 2004 December 2005
NCT00130845 Completed Phase 3 Octreotide Acetate in Microspheres in Patients With Diabetic Retinopathy February 2000 December 2005
NCT00131144 Completed Phase 3 Octreotide Acetate in Microspheres in Patients With Diabetic Retinopathy November 1999 December 2005
NCT00155454 Completed N/A Intravitreal Long Acting Gas in the Prevention of Early Postoperative Vitreous Hemorrhage in Diabetic Vitrectomy September 2004 December 2012
NCT00198471 Completed Phase 2 Assessment of Intravitreous Injections of Vitrase for Inducing Posterior Vitreous Detachment July 2005 November 2006
NCT00198497 Completed Phase 3 Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage June 1999 June 2003
NCT00198510 Completed Phase 3 Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage November 1998 March 2003
NCT00231023 Completed Phase 2 Triamcinolone Acetonide Injections to Treat Diabetic Macular Edema September 2005 May 2006
NCT00266695 Completed Phase 3 Treatment for Completers of the Study B7A-MC-MBCM January 2006 August 2008
NCT00295828 Completed Phase 1 A Pilot Study for the Treatment of Iris Neovascularization With Macugen January 2006 September 2008
NCT00336323 Completed Phase 2 A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin) June 2006 February 2008
NCT00337298 Completed N/A The Effect of Amlodipine and Lisinopril on Retinal Autoregulation in Type 1 Diabetes July 2006 February 2009
NCT00343603 Completed Tracking Optical Coherence Tomography October 2004 January 2011
NCT00355680 Completed Phase 3 Green Laser Photocoagulation Study in Proliferative Diabetic Retinopathy December 2005 July 2006
NCT00385333 Completed Phase 2 Metabolic Mapping to Measure Retinal Metabolism September 29, 2006 September 16, 2010
NCT00387582 Completed Phase 2 Efficacy Study of Lucentis in the Treatment of Diabetic Macular Edema July 2006 February 2009
NCT00401115 Completed Phase 1 Safety and Tolerability of MS-R001 in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy September 2006 June 2008
NCT00403195 Completed Clinical and Pathophysiological Description of Ocular Ischemic Syndrome November 2006 January 2009
NCT00406991 Completed Phase 2 Retinal Blood Flow and Microthrombi in Type 1 Diabetes June 2003 March 2006
NCT00411333 Completed Early Phase 1 Vascular Remodeling and the Effects of Angiogenic Inhibition in Diabetic Retinopathy July 2006 July 2009
NCT00411970 Completed Phase 4 20- Versus 23- Gauge System for Pars Plana Vitrectomy September 2004 October 2007
NCT00414999 Completed Phase 1 A Phase 1 Safety Study of TG100801 Eye Drops in Healthy Volunteers November 2006 February 2007
NCT00423059 Completed N/A Intravitreal Bevacizumab for Proliferative Diabetic Retinopathy December 2006 March 2007
NCT00442156 Completed The Course of Response to Focal Photocoagulation for DME January 2007 June 2008
NCT00443521 Completed Phase 2/Phase 3 Triamcinolone as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative Diabetic Retinopathy March 2005 July 2006
NCT00444600 Completed Phase 3 Laser-Ranibizumab-Triamcinolone for Diabetic Macular Edema March 2007 February 2014
NCT00500097 Completed N/A Diabetic Retinopathy and Diabetic Macular Edema Screening by Non-Physicians With Limited Training May 2005 June 2006
NCT00511875 Completed Phase 2 Evaluation of Doxycycline Verses Placebo for the Treatment of Severe Nonproliferative or Mild or Moderate Proliferative Diabetic Retinopathy July 2008 May 2012
NCT00542178 Completed Phase 3 Evaluating How the Treatments in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study Affect Diabetic Retinopathy (The ACCORD Eye Study) October 2003 December 2009
NCT00545870 Completed Phase 3 Bevacizumab Versus Ranibizumab for Diabetic Retinopathy June 2008 April 2013
NCT00548197 Completed Phase 1 Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment February 2007 March 2008
NCT00556114 Completed A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging January 2007 July 2013
NCT00594152 Completed Phase 3 Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT) January 1993 January 1995
NCT00596297 Completed Phase 1/Phase 2 Preoperative Bevacizumab for Vitreous Hemorrhage November 2007 September 2008
NCT00604383 Completed Phase 3 Protein Kinase C (PKC) Inhibitor-Diabetic Retinopathy Phase 3 Study March 2001 June 2005
NCT00619034 Completed N/A Pharmacological Intervention in Diabetic Retinopathy September 2007 December 2010
NCT00647439 Completed Genetics and Markers of Degenerative and Inflammatory Eye Diseases March 27, 2008 December 4, 2018
NCT00000151 Completed Phase 3 Early Treatment Diabetic Retinopathy Study (ETDRS) December 1979
NCT00000153 Completed Phase 3 Krypton-Argon Regression of Neovascularization Study (KARNS) December 1984
NCT00000154 Completed Phase 3 Diabetic Retinopathy Vitrectomy Study (DRVS) October 1976
NCT00000159 Completed Phase 3 Sorbinil Retinopathy Trial (SRT) August 1983
NCT00000160 Completed Phase 3 Diabetic Retinopathy Study (DRS) January 1972
NCT00001346 Completed Diabetic Retinopathy and Visual Function Study November 1992 October 2000
NCT00001395 Completed Long Term Follow-Up of Diabetic Retinopathy March 1994 August 2000
NCT00001612 Completed Long-Term Follow-Up of Patients Enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS) May 1997 August 2000
NCT00001733 Completed Screening for Studies on Retinovascular Diseases March 6, 1998 July 2, 2008
NCT00005761 Completed Blood Factors and Diabetic Retinopathy May 23, 2000 December 7, 2010
NCT00035906 Completed Phase 2 Research Study in Patients With Persistent Macular Edema October 2001 August 2004
NCT00041444 Completed Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye Study June 2002 November 2006
NCT00069056 Completed Phase 1 Pilot Study of Laser Photocoagulation Therapy for Diabetic Macular Edema September 10, 2003 August 15, 2007
NCT00090519 Completed Phase 3 Reduction in the Occurrence of Center-Involved Diabetic Macular Edema February 2004 April 2010
NCT00101764 Completed Phase 1 Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorders January 5, 2005 May 20, 2008
NCT00105404 Completed Phase 3 Treatment of Diabetic Macular Edema: Triamcinolone Injections Vs. Laser Photocoagulation March 9, 2005 October 30, 2006
NCT00690768 Completed Phase 2 Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA) March 2008 May 2008
NCT00709319 Completed Evaluation of Vitrectomy for Diabetic Macular Edema July 2005 February 2009
NCT00711490 Completed Phase 1/Phase 2 Sirolimus to Treat Diabetic Macular Edema July 2008 January 2011
NCT00712842 Completed Neurovascular Coupling in Patients With Early Stage Diabetes Retinopathy January 2007 December 2011
NCT00720317 Completed Diabetic Retinopathy and Sickle Trait May 2008 July 2010
NCT00763802 Completed Validation of a Predictive Model to Estimate the Risk of Conversion to Clinically Significant Macular Edema and/or Vision Loss in Mild Nonproliferative Diabetic Retinopathy in Diabetes Type 2 September 2007 May 2011
NCT00797134 Completed Retinal Thickness Analysis Using Optical Coherence Tomography November 2008 July 2010
NCT00797524 Completed Function and Structure Imaging in Different Retinal Diseases: Retinal Leakage Analyzer Versus Optical Coherence Tomography November 2008 October 2010
NCT00799695 Completed N/A Diabetic Retina Exam Rate Does Not Increase With Phone Reminders in Non-HMO Population January 2008 November 2008
NCT00804921 Completed Phase 2 Effectiveness of Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis in Intraocular Pressure (IOP) After Bevacizumab
NCT00806169 Completed Phase 3 Combined Triple Therapy in Diabetic Retinopathy (DRP) April 2006 November 2008
NCT00840541 Completed Phenotyping Diabetic Retinopathy January 2009 January 2012
NCT00864838 Completed Phase 2 Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis for Ocular Hypertension Control After Intravitreal Bevacizumab June 2008 March 2009
NCT00886392 Completed Diabetic Macular Edema Severity at Diagnosis June 2006 April 2008
NCT00900887 Completed Phase 2 Topic Antiinflammatory Therapy Added to Selective Photocoagulation in Macular Edema April 2008 March 2015
NCT00904592 Completed N/A A Study on Traditional Chinese Medicine (TCM) Comprehensive Protocol of Prevention and Control in Diabetic Retinopathy September 2008 April 2011
NCT00906659 Completed Visual Function, Center Point Thickness and Macular Volume After Photocoagulation January 2006 March 2008
NCT00917553 Completed Phase 2 Evaluation of Effect of Doxycycline Verses Placebo on Retinal Function and Diabetic Retinopathy July 2009 July 2012
NCT00970723 Completed N/A High Blood Pressure and Sleep Apnea in Diabetic Macular Edema September 2009 January 2014
NCT01075347 Completed Phase 1 Topical Autologous Serum Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries March 2007 March 2008
NCT01102946 Completed Phase 2 Panretinal Photocoagulation (PRP) Plus Ranibizumab for Proliferative Diabetic Retinopathy February 2009 February 2011
NCT01115257 Completed N/A Severe Proliferative Diabetic Retinopathy October 2001
NCT01131650 Completed Prevalence of Diabetic Retinopathy in São José do Rio Preto-SP-Brazil March 2009 May 2010
NCT01179555 Completed N/A Confronting Unequal Eye Care in Pennsylvania October 2010 May 2014
NCT01189461 Completed Phase 3 Study To Evaluate Safety And Tolerability Of Pegaptanib Sodium In Patients With Diabetic Macular Edema January 2011 July 2012
NCT01201161 Completed Phase 2 Ranibizumab for Diabetic Traction Retinal Detachment December 2008 January 2010
NCT01202461 Completed Phase 1 Triple Therapy of Pars Plana Vitrectomy and Grid/Focal Laser for Diabetic Macular Edema (DME) August 2010 September 2010
NCT01220804 Completed Evaluation of Blood-retinal Barrier Functional Alterations by Optical Coherence Tomography November 2010 March 2013
NCT01223612 Completed Phase 4 Lucentis (Ranibizumab) in Diabetic Macular Oedema: a Treatment Evaluation October 2010 July 2012
NCT01225653 Completed Phase 4 Topical Application of Latanoprost in Diabetic Retinopathy November 2010 December 2014
NCT01255293 Completed N/A Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments November 2010 October 2012
NCT01257815 Completed Phase 4 Ranibizumab Treatment of Diabetic Macular Oedema With Bimonthly Monitoring After a Phase of Initial Treatment January 2011 April 2013
NCT01270542 Completed N/A Avastin for PDR (Proliferative Diabetic Retinopathy) June 2009 July 2012
NCT01295775 Completed Phase 2 Diabetic Retinopathy Sulodexide Study February 2009 May 2011
NCT01298076 Completed Phase 2 Intravitreal Bevacizumab (Avastin®) Versus Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema October 2010 September 2014
NCT01306981 Completed Phase 4 Ranibizumab in Diabetic Vitrectomy. A Prospective, Randomised Controlled Trial of Ranibizumab Pre-treatment in Diabetic Vitrectomy - a Pilot Study March 30, 2011 March 12, 2013
NCT01323348 Completed Phase 3 Effect of Diabetes Education During Retinal Ophthalmology Visits on Diabetes Control October 2011 January 2015
NCT01364129 Completed N/A The Comparative Effectiveness of Telemedicine to Detect Diabetic Retinopathy August 2006 June 2012
NCT01373476 Completed Phase 2 Multicentre, Randomized, Controlled Trial of Qideng Mingmu Capsule in The Treatment of Diabetic Retinopathy March 2011 March 2013
NCT01415037 Completed Annular Array Ultrasound in Ophthalmology October 2011 December 2016
NCT01440660 Completed Phenotypes of Nonproliferative Diabetic Retinopathy in DM 2 Patients Identified by OCT, CFP, RLA and mfERG (DIAMARKER) January 2012 September 2014
NCT01445899 Completed Phase 2 PF-04523655 Dose Escalation Study, and Evaluation of PF-04523655 With/Without Ranibizumab in Diabetic Macular Edema (DME) February 2012 November 2013
NCT01476449 Completed Phase 2 Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema November 2011 September 2016
NCT01504724 Completed Phase 4 Effect of the Adjunctive IVB Before PRP August 2011 August 2013
NCT01614327 Completed Computer-based Screening for Diabetic Retinopathy August 2012 February 24, 2015
NCT01622816 Completed Comparing Visual Acuity Measurements (How Well You Can See) Using a Standard ETDRS Chart & a Handheld ETDRS Chart March 2012 March 2014
NCT01625598 Completed Computer Detection of Diabetic Retinopathy Compared to Clinical Examination April 2012 April 2014
NCT01628289 Completed N/A The Cost-effectiveness of Screening for Diabetic Retinopathy in Hong Kong February 2009 August 2010
NCT01692938 Completed Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO October 2012 November 2012
NCT01694212 Completed N/A Preoperative Topic Diclofenac as a Prevention of Postoperative Macular Edema in Patients With Diabetic Retinopathy October 2012 December 2016
NCT01726075 Completed Phase 2/Phase 3 Trial to Assess the Efficacy of Neuroprotective Drugs Administered Topically to Prevent or Arrest Diabetic Retinopathy February 2013 November 2015
NCT01728883 Completed Diabetic Retinopathy And the Myvisiontrack® (DRAMA) Study April 2013 March 2017
NCT01743781 Completed N/A Uptake of Comprehensive Eye Examination Trial July 2013 September 2013
NCT01744132 Completed N/A Overcoming Barriers in Vision Care Utilization of African Americans With Diabetes October 2012 October 2016
NCT01746563 Completed Phase 1/Phase 2 Intravitreal Ranibizumab Combined With Panretinal Photocoagulation in Patients With Proliferative Diabetic Retinopathy May 2011 August 2012
NCT01785667 Completed Incidence of Retinopathy and Associated Risk Factors in Children and Young Adults With Type 1 Diabetes in Denmark January 2011 February 2013
NCT01787669 Completed Phase 2 Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema June 2013 October 2017
NCT01824862 Completed Reduction of Foveal Sensitivity in Eyes With Diabetic Macular Edema January 2013 July 2013
NCT01837121 Completed N/A a Trial of Using SMS Reminder Among Diabetic Retinopathy Patients in Rural China January 2015 June 2017
NCT01871207 Completed Serum and Intraocular Levels of Erythropoietin and VEGF in Type 2 Diabetes Patients With Proliferative Retinopathy May 2011 January 2012
NCT01875783 Completed N/A OCT Screening for Diabetic Macular Edema at Primary Diabetes Care Visits March 17, 2014 July 15, 2016
NCT01908816 Completed Phase 3 An Open-label Extended Clinical Protocol of Ranibizumab to Evaluate Safety and Efficacy in Rare VEGF Driven Ocular Diseases. September 26, 2013 January 8, 2016
NCT01927315 Completed Phase 4 Effects of Fenofibrate on Endothelial Progenitor Cells in Diabetes August 2013 December 2019
NCT01946997 Completed Evaluation of the Retina of Subjects Without Diabetes Mellitus and Subjects With Diabetes Mellitus Without Diabetic Retinopathy Using Optical Coherence Tomography July 2006 December 2010
NCT01950663 Completed N/A RETeval Study for Diabetic Retinopathy September 2013 April 2014
NCT01988246 Completed Phase 1/Phase 2 Prevention of Macular Edema In Patients With Diabetic Retinopathy Undergoing Cataract Surgery December 2013 January 14, 2020
NCT02040441 Completed Phase 2/Phase 3 Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuria March 2014 November 2018
NCT02077127 Completed Monocyte Chemoattractant Protein-1 2518A/G Polymorphism September 2011 April 2013
NCT02085681 Completed N/A Study of Effectiveness of Telemedicine in Identifying Diabetic Retinopathy Cases May 2014 March 2015
NCT02099981 Completed Phase 1 Restoration of Retinal Vascular Responses in Type 1 Diabetic Patients July 2016 December 2017
NCT02121340 Completed N/A Collaborative Care for Depression and Diabetic Retinopathy in African Americans May 2014 December 2018
NCT02126423 Completed Resistance to Antibiotics in Patients Receiving Eye Injections May 2014 September 2014
NCT02217306 Completed Contrast Sensitivity and Diabetic Macular Edema January 2014 August 2014
NCT02232503 Completed Prevalence of DIAbetic RETinopathy and Impact of Genetic Factors in the Development of Diabetic Retinopathy of Patients With Type 1 and 2 Diabetes Mellitus in SlovaKia February 2015 November 2015
NCT02249897 Completed Phase 4 PRELIMINARY EVALUATION OF PHARMACOLOGICAL LOWERING OF AGEs January 2015 December 2017
NCT02311504 Completed Eye Screening in German Secondary Diabetes Care Centers January 2014 September 2015
NCT02326259 Completed Evaluation of Progression of Diabetic Retinopathy With Rapid Correction of Hyperglycemia March 2015 March 2022
NCT02334137 Completed A Pilot Project to Assess the Impact of Diabetes Education During Ophthalmology Visits November 2014 December 2015
NCT02339909 Completed N/A Incentives in Diabetic Eye Assessment by Screening March 2015 July 2016
NCT02366468 Completed Phase 4 Study of Efficacy of Ranibizumab in Different Regimens in Patients With Diabetic Macula Edema February 23, 2015 June 8, 2017
NCT02390245 Completed N/A Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study September 2014 August 2020
NCT02391558 Completed Clinical Evaluation of Noninvasive OCT Angiography Using a Zeiss OCT Prototype to Compare to Fluorescein Angiography September 2015 April 2016
NCT02432547 Completed Phase 4 Laser Therapy Combined With Intravitreal Aflibercept vs Intravitreal Aflibercept Monotherapy (LADAMO) June 15, 2017 May 24, 2022
NCT02457975 Completed Early Phase 1 Photobiomodulation for the Treatment of Diabetic Macular Edema June 2015 August 30, 2019
NCT02475109 Completed Phase 1 Study of Topical Ocular PAN-90806 in PDR August 2015 July 2016
NCT02521116 Completed N/A Comparison of Retinal Oxygenation and Retinal Vessel Diameters in Healthy Subjects and Patients With Diabetic Retinopathy or Retinal Vein Occlusion Between DVA and Oxymap February 2016 February 28, 2018
NCT02559180 Completed Phase 4 Treatment of Diabetic Macular Edema With Aflibercept in Subjects Previously Treated With Ranibizumab or Bevacizumab October 2015 December 2020
NCT02579837 Completed N/A CLEAR SIGHT: A Trial of Non-Mydriatic Ultra-Widefield Retinal Imaging to Screen for Diabetic Eye Disease March 2016 December 2020
NCT02590094 Completed N/A Preoperative Bevacizumab and Ziv-Aflibercept Administration in PDR Subjects Undergoing PPV October 2015 January 4, 2019
NCT02621580 Completed N/A Investigating the Structural and Functional Changes to the Retina Following PRP in Diabetic Retinopathy Patients September 2012 August 2017
NCT02625649 Completed Effect of Gastric Bypass Surgery on Diabetes Status and Microvascular Complications in Obese Type 2 Diabetic Patients January 2016 June 2017
NCT02634333 Completed Phase 3 Anti-VEGF Treatment for Prevention of PDR/DME January 2016 May 11, 2022
NCT02637245 Completed Imaging Parameters and DME Treatment Response May 2015 December 2017
NCT02645383 Completed N/A PASCAL Laser Platform Produces Less Pain Responses Compared To Conventional Laser System May 2014 June 2015
NCT02647515 Completed Phase 4 Intravitreal Ranibizumab Injection as Adjuvant in the Treatment of Postvitrectomy Diabetic Vitreous Hemorrhage Accompanied by Neovascular Glaucoma January 2013 December 2014
NCT02662010 Completed The Relationship Between Advanced Glycation Endproducts and Diabetes March 2016 January 17, 2020
NCT02691312 Completed Pediatric Type 1 Diabetes and Retinopathy July 2016 December 27, 2018
NCT02691429 Completed N/A Applicability of the Acai Fruit (Euterpe Oleracea) Dye for Chromovitrectomy in Humans February 2016 May 2017
NCT02806830 Completed N/A Ocular Discomfort Assessment After Intravitreal Injections April 2016 July 1, 2017
NCT02816073 Completed N/A Pattern Scanning Laser Pan-retinal Photocoagulation in Proliferative Diabetic Retinopathy December 2012 April 2016
NCT02823600 Completed N/A Feasibility Study of Retinal Screening Using the RetinaVue 100 Camera in Outpatient Dialysis Centers July 2016 May 2017
NCT02866734 Completed N/A Diabetic Retinopathy Screening in Private Practice September 1, 2016 June 1, 2018
NCT02874313 Completed Phase 4 CPAP Effect on the Progression of Diabetic Retinopathy in Patients With Sleep Apnea August 2016 March 2021
NCT02876393 Completed A Systematic Study of Retinal Structure and Function in Diabetic Macular Oedema November 2014 January 2017
NCT02876744 Completed Correlation Between Macular Ischemia and Peripheral Ischemia in Patients With Diabetes April 4, 2017 December 15, 2020
NCT02924311 Completed Routine Clinical Practice for Use of Intravitreal Aflibercept Treatment in Patients With Diabetic Macular Edema September 21, 2016 December 6, 2019
NCT02927561 Completed Automated Diagnostic Test for Diabetic Retinopathy in Brazilian Mass Screening June 2015 September 2016
NCT02963441 Completed A Multi-center Study to Evaluate Performance of an Automated Device for the Detection of Diabetic Retinopathy January 2017 December 2017
NCT03010397 Completed Progression of Diabetic Retinopathy. Identification of Signs and Surrogate Outcomes December 2016 March 6, 2019
NCT03030729 Completed Macular Thickness Measurements Using Retinal-thickness OCT March 14, 2017 January 14, 2018
NCT03069729 Completed Thermal Screening for Early Diabetic Peripheral Neuropathy (DPN) March 8, 2017 September 1, 2019
NCT03071068 Completed Phase 2 A Study to Evaluate the Safety and Efficacy of THR-317 for the Treatment of Diabetic Macular Oedema (DME) December 22, 2016 April 2018
NCT03078231 Completed Pilot Assessment of EyeArt as an Automated Diabetic Retinopathy Screening Tool February 17, 2017 April 24, 2017
NCT03112005 Completed Assessment of EyeArt as an Automated Diabetic Retinopathy Screening Tool April 17, 2017 May 31, 2018
NCT03150654 Completed N/A The Effect of Laser Treatment on Macular Pigment of Eye in Cases With Diabetes October 1, 2015 July 12, 2016
NCT03238963 Completed Phase 2 A Study That Tests BI 1467335 in Patients With Diabetic Eye Disease (Diabetic Retinopathy). It Looks at the Way BI 1467335 is Taken up, the Effects it Has, and How Well it is Tolerated. September 19, 2017 May 14, 2020
NCT03278587 Completed N/A Village-Integrated Eye Worker Trial II - Pilot May 31, 2018 March 1, 2020
NCT03374020 Completed Retinal Imaging Using NOTAL-OCT January 17, 2017 December 1, 2018
NCT03403283 Completed Dyslipidemia and Diabetic Retinopathy January 2014 April 30, 2023
NCT03437018 Completed MONITORING OF MODERATE DIABETIC RETINOPATHY BY TELE-EXPERTISE October 10, 2019 June 16, 2022
NCT03439345 Completed Phase 4 Lowering Events in Non-proliferative Retinopathy in Scotland July 23, 2018 February 16, 2024
NCT03453281 Completed Phase 4 Early Anatomical, Physiological, and Clinical Changes in Diabetic Macular Edema After Intravitreal Aflibercept Injection October 10, 2017 May 18, 2018
NCT03476967 Completed Effect of Laser Treatment for Diabetic Retinopathy on the Optic Disc Topography January 2014 January 2017
NCT03478306 Completed Phase 3 Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm March 27, 2018 June 12, 2021
NCT03499223 Completed Phase 2 A Study to Evaluate THR-317 and Ranibizumab Combination Treatment for Diabetic Macular Oedema (DME) April 20, 2018 July 18, 2019
NCT03511898 Completed Phase 1 A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME) May 18, 2018 May 22, 2019
NCT03528720 Completed Evaluation System and Clinical Application for Diabetic Retinopathy June 13, 2017 April 30, 2018
NCT03531294 Completed Phase 2 Intravitreal Aflibercept as Indicated by Real-Time Objective Imaging to Achieve Diabetic Retinopathy Improvement May 23, 2018 April 9, 2021
NCT03571659 Completed Comparison of Different Fluence Settings for Yellow Subthreshold Laser Treatment in Diabetic Macular Edema December 22, 2014 August 11, 2015
NCT03658980 Completed N/A Integrating DR Into Mainstream Health System in Bangladesh December 15, 2018 August 31, 2019
NCT03660345 Completed Phase 3 PPV With Internal Limiting Membrane Peeling for Treatment-Naïve DME September 4, 2018 May 4, 2021
NCT03660371 Completed N/A ILM Peeling in PDR Patients Undergoing PPV for VH September 4, 2018 March 4, 2020
NCT03660384 Completed N/A Silicone Oil Versus Gas in PDR Patients Undergoing Vitrectomy September 4, 2018 March 4, 2020
NCT03666923 Completed Phase 1 A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME) September 17, 2018 November 20, 2019
NCT03672656 Completed N/A Pattern Laser Versus Conventional Laser in Diabetic Retinopathy January 1, 2008 January 25, 2014
NCT03702374 Completed Phase 3 Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy September 26, 2018 December 31, 2020
NCT03821753 Completed The Effect of the Glycemic Variability on Macular Retinal Microcirculation and Cognitive Functions in Patient With Type 1 Diabetes January 7, 2019 July 8, 2021
NCT03843840 Completed Dual Wavelength OCT February 15, 2019 October 21, 2020
NCT03902925 Completed Phase 1/Phase 2 Pain During Pars Plana Vitrectomy With Sub-tenon Anesthesia January 1, 2019 October 31, 2019
NCT03904056 Completed N/A ETDRS PRP With IVR Versus Retinal Photocoagulation Targeted to Ischemic Retina With IVR for the Treatment of PDR January 1, 2014 July 1, 2017
NCT03912961 Completed The Santa Cruz Diabetic Retinopathy Utilizing Artificial Intelligence Study January 21, 2019 October 15, 2019
NCT03956797 Completed N/A Long Term Safety of Cooling Anesthesia for Intravitreal Injection April 15, 2019 April 2, 2021
NCT03962296 Completed Phase 4 A Multicenter, Randomized, Double-blind Non-inferiority Trial to Evaluate the Efficacy and Safety of Entelon® November 21, 2012 January 26, 2015
NCT03973762 Completed N/A A Blinded, Self-control Trial to Evaluate an Artificial Intelligence Based CAD System for Diabetic Retinography May 31, 2019 August 15, 2020
NCT04009980 Completed N/A Long-term Retinal Changes After Topical Citicoline Administration in Patients With Mild Signs of Diabetic Retinopathy in Type 1 Diabetes Mellitus. September 23, 2015 June 7, 2019
NCT04018326 Completed Loss to Follow-up in PDR Patients May 1, 2013 December 25, 2018
NCT04018482 Completed Phase 4 Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study) July 16, 2019 August 14, 2019
NCT04018833 Completed Intravitreal Ranibizumab or Aflibercept After Bevacizumab in Diabetic Macular Edema January 1, 2012 June 30, 2016
NCT04071977 Completed Phase 2 Combined Antioxidant Therapy on Oxidative Stress in Aqueous and Vitreous Humor of Diabetic Retinopathy Patients March 25, 2020 December 31, 2021
NCT04132401 Completed N/A AI for the Detection of Retinal Disease and Glaucoma in Patients With Diabetes Mellitus in Primary Care May 1, 2021 September 26, 2023
NCT04141891 Completed N/A Advancing Understanding of Transportation Options December 12, 2019 December 21, 2023
NCT04160988 Completed A Single-center, Retrospective Study to Evaluate the Clinical Performance of Artificial Intelligence Medical Assisted Diagnostic Software (VeriSee DR) for Screening of Diabetic Retinopathy in Patients With Diabetes Mellitus December 16, 2019 May 11, 2020
NCT04265261 Completed Phase 2 A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy June 5, 2020 July 19, 2023
NCT04302012 Completed Assessment of EyeArt Performance With Retinal Imaging Devices December 18, 2019 February 27, 2020
NCT04359771 Completed Phase 4 Transfoveal Micropulse Laser for Center Involving Diabetic Macular Edema January 22, 2018 September 25, 2018
NCT04378972 Completed Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy September 16, 2019 December 2, 2019
NCT04418427 Completed Phase 2 ADVM-022 Intravitreal Gene Therapy for DME May 28, 2020 November 22, 2022
NCT04424290 Completed Phase 1/Phase 2 HORNBILL: A Study to Test Different Doses of BI 764524 in Patients Who Have Had Laser Treatment for a Type of Diabetic Eye Disease Called Diabetic Retinopathy With Diabetic Macular Ischemia June 12, 2020 April 28, 2023
NCT04477707 Completed A Study That Uses Data From Routine Eye Examinations of Patients Participating in Studies FIDELIO-DKD and FIGARO-DKD to Explore Whether Finerenone Can Delay the Progression of a Diabetes Complication That Affects the Eyes (Diabetic Retinopathy ,DR) July 23, 2020 June 25, 2021
NCT04527107 Completed Phase 2 A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema July 31, 2020 November 22, 2023
NCT04610749 Completed Diabetic Retinopathy as a Marker of Cognitive Dysfunction and Depression November 25, 2020 February 25, 2022
NCT04612868 Completed N/A Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Fundus Images October 16, 2020 December 26, 2021
NCT04619303 Completed Phase 4 Intravitreal Dexamethasone vs Bevacizumab in Aboriginal People With DMO February 7, 2017 February 14, 2020
NCT04637217 Completed Retinal Neurodegenerative and Vascular Changes in Diabetic Patients July 1, 2018 July 1, 2019
NCT04674254 Completed Phase 4 Macular Perfusion Changes After Anti-VEGF Versus Targeted Retinal Photocoagulation in Proliferative Diabetic Retinopathy March 30, 2021 March 15, 2023
NCT04692688 Completed Phase 2 Study of the Safety and Efficacy of APX3330 in Diabetic Retinopathy April 8, 2021 January 25, 2023
NCT04722991 Completed Phase 2 Non-proliferative Diabetic Retinopathy Treated With Runcaciguat March 17, 2021 April 22, 2024
NCT04723160 Completed Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph August 10, 2020 May 30, 2021
NCT04729023 Completed N/A Pars Plana Vitrectomy Combined With Phacoemulsification Cataract Surgery in Phakic Diabetes Retinopathy Patients February 1, 2021 September 5, 2022
NCT04732208 Completed Automated Screening of Diabetic Retinopathy Using a Smartphone-based Camera April 20, 2022 August 24, 2022
NCT04774822 Completed Validation Study of RETINA-AI Galaxy™, an Automated Diabetic Retinopathy Screening Device March 25, 2021 August 31, 2021
NCT04795726 Completed N/A A Study That Uses Data From Routine Eye Examinations of Patients Participating in Studies FIDELIO-DKD and FIGARO-DKD to Explore Whether Finerenone Can Delay the Progression of a Diabetes Complication That Affects the Eyes (Diabetic Retinopathy, DR) March 10, 2021 June 30, 2021
NCT04829084 Completed N/A Augmenting Referral Pathway to Improve Uptake of Retinal Services by Diabetic Patients February 26, 2021 December 30, 2021
NCT04834648 Completed N/A Improve Timely Referral Flow and Compliance of Diabetic Retinopathy Patients March 15, 2021 December 30, 2021
NCT04885153 Completed N/A Effects of Oral Fenofibrate on Retinal Thickness and Macular Volume November 1, 2016 July 1, 2017
NCT04905459 Completed ARDA Software for the Detection of mtmDR September 30, 2021 May 23, 2022
NCT04919499 Completed Phase 1/Phase 2 A Study of BI 765128 in Patients With an Eye Condition Called Diabetic Macular Ischemia Who Have Received Laser Treatment July 30, 2021 August 7, 2023
NCT04930224 Completed Serum GPER-1 and Oxidant/Antioxidant Levels on Retinopathy in Diabetic Patients July 1, 2019 April 25, 2020
NCT04984200 Completed Assessment of EyeArt Performance With Retinal Cameras July 13, 2021 August 19, 2022
NCT05022615 Completed Comparing 3 Imaging Systems September 29, 2021 March 7, 2023
NCT05105620 Completed Deep Learning for Fluorescein Angiography and Optical Coherence Tomography Macular Thickness Map Image Translation August 1, 2018 February 1, 2021
NCT05135195 Completed N/A A Virtual Reality Platform Simulating Visual Impairment for Testing of Electronic Travel Aids and Performing Orientation and Mobility Training October 24, 2021 October 20, 2022
NCT05182580 Completed N/A Bangladesh PRODUCTIVity in Eyecare Trial March 20, 2022 July 31, 2022
NCT05223556 Completed Self-testing Diagnosis Imaging Model for Diabetic Retinopathy February 1, 2022 December 30, 2022
NCT05231174 Completed N/A Efficacy of Using Large Language Model to Assist in Diabetic Retinopathy Detection May 1, 2023 July 30, 2023
NCT05344690 Completed SLMAP and EPO Genetic Polymorphism in Diabetic Retinopathy May 20, 2022 June 30, 2023
NCT05368623 Completed Validation Study of RETINA-AI Galaxy™ v2.0, an Automated Diabetic Retinopathy Screening Device November 3, 2022 March 31, 2023
NCT05409235 Completed Phase 2 Nesvategrast (OTT166) in Diabetic Retinopathy (DR) July 29, 2022 December 29, 2023
NCT05417152 Completed Single In-Clinic Encounter With the Notal Vision Home OCT by DME Patients June 29, 2022 March 30, 2023
NCT05441072 Completed Validation of Bulbicam for DR- and AMD-patients December 19, 2022 June 15, 2023
NCT05491746 Completed N/A Diabetic Retinopathy Tethered Augmented Reality With Eye4 Study July 1, 2022 October 1, 2022
NCT05543564 Completed Prophylactic PRP in Moderate NPDR February 1, 2019 March 31, 2020
NCT05600179 Completed OCTA in Epivascular Glia After Dex Implant January 1, 2021 September 30, 2022
NCT05608265 Completed N/A Real-time Eye Tracking and Imaging of the Eye in Diabetic Retinopathy Patients August 31, 2022 March 21, 2023
NCT05686421 Completed N/A Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp Configurations March 30, 2023 April 28, 2023
NCT05857943 Completed N/A Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Funduscopic Images March 29, 2023 October 10, 2023
NCT06038968 Completed Early Phase 1 Methotrexate Infusion and Intrasilicone Injection During Diabetic Vitrectomy September 1, 2022 January 1, 2024
NCT06173245 Completed N/A Subfoveal Choroidal Thickness and Visual Acuity After Intravitreal Injection of Ranibizumab in Diabetic Retinopathy February 1, 2021 February 1, 2023
NCT06213896 Completed Detecting Eye Diseases Via Hybrid Deep Learning Algorithms From Fundus Images March 1, 2023 April 18, 2024
NCT05773495 Enrolling by invitation N/A Implementation of Teleophthalmology in Urban Health Systems Study March 19, 2024 August 2026
NCT05254535 Enrolling by invitation N/A I-TRUST: Implementation of Teleophthalmology in Rural Health Systems Study March 28, 2023 January 31, 2027
NCT05074342 Enrolling by invitation Project Open - Use of Administrative Health Data to Increase Diabetic Retinopathy Screening February 1, 2022 December 31, 2024
NCT05057403 Enrolling by invitation UK Imaging Diabetes Study Seeing Diabetes Clearly May 30, 2022 June 2034
NCT05132660 Enrolling by invitation Early Phase 1 Treating Early Stage Diabetic Retinopathy July 1, 2022 December 31, 2028
NCT03076697 Enrolling by invitation Smartphone Screening for Eye Diseases April 16, 2015 August 30, 2028
NCT05276778 Enrolling by invitation Diabetic Retinopathy Screening in General Practice February 28, 2022 July 2023
NCT05607810 Enrolling by invitation Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT) August 10, 2022 March 2026
NCT05773209 Not yet recruiting N/A Choroidal and Retinal Changes After RLRL Therapy in Diabetes and Diabetic Retinopathy April 30, 2023 December 30, 2023
NCT05527535 Not yet recruiting Expansion of Integrated AI Solution for Diabetic Retinopathy Screening in Thailand October 3, 2022 September 30, 2023
NCT04699864 Not yet recruiting N/A Evaluation of NeoRetina Artificial Intelligence Algorithm for the Screening of Diabetic Retinopathy at the CHUM April 2024 December 2026
NCT06076720 Not yet recruiting N/A Evaluation of New Head-mounted Visual Aids Among Patients With Low Vision October 10, 2023 October 10, 2024
NCT06272565 Not yet recruiting Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage March 1, 2024 December 30, 2026
NCT05778370 Not yet recruiting Correlation Between HBA1c Level and Thickness of Both Macula and Choroid in Patients With Type 2 Diabetes Mellitus April 15, 2023 December 1, 2023
NCT06154746 Not yet recruiting Analysis of Risk Factors of Diabetic Retinopathy June 2024 June 2025
NCT06191094 Not yet recruiting Phase 4 Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy August 2024 January 2027
NCT06146699 Not yet recruiting Prevalence of Diabetic Retinopathy in Type 2 Diabetic Patients December 2023 February 2025
NCT05324189 Not yet recruiting Automated AI-based System for Early Diagnosis of Diabetic Retinopathy April 18, 2022 December 1, 2024
NCT06257082 Not yet recruiting N/A Video-based Patient Education Intervention for Diabetic Eye Screening in Latinx Communities September 2024 September 2025
NCT05992415 Not yet recruiting N/A New York City Eye Study (NYCES) July 1, 2024 June 30, 2029
NCT05806957 Not yet recruiting Pivotal Trial to Assess the Clinical Performance of Ophthal-360 for the Detection of Diabetic Retinopathy June 1, 2023 September 30, 2024
NCT06343961 Not yet recruiting N/A Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy April 18, 2024 December 2025
NCT04794907 Not yet recruiting Retinal Care Data Repository December 31, 2022 December 2030
NCT04008121 Not yet recruiting Early Phase 1 Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium April 2024 July 2024
NCT06188013 Not yet recruiting Proteomic Study of Plasma Exosomes in Patients With Diabetic Retinopathy January 2, 2024 June 30, 2024
NCT06423274 Not yet recruiting Comparing Artificial Intelligence for Assisted Diagnosis of Diabetic Retinopathy May 10, 2024 December 31, 2025
NCT06198543 Not yet recruiting Study on Exosome Changes in Patients With Proliferative Diabetic Retinopathy January 2024 April 2025
NCT05471986 Not yet recruiting Multicenter Diagnostic Clinical Performance Study For Automated Detection of Diabetic Retinopathy August 1, 2024 December 1, 2024
NCT04499820 Recruiting N/A Effect of OMEGA3 Supplementation in Diabetic Retinopathy June 26, 2020 November 25, 2024
NCT05147701 Recruiting Phase 1 Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Eye Diseases February 1, 2022 January 2026
NCT01320345 Recruiting Phase 3 The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye. November 3, 2016 December 2025
NCT04650165 Recruiting 10-year Progression of Diabetic Retinopathy: Identification of Signs and Surrogate Outcomes June 1, 2021 December 31, 2024
NCT05282680 Recruiting The Hong Kong Diabetes Biobank February 1, 2014 December 31, 2063
NCT04661358 Recruiting Phase 3 Fenofibrate for Prevention of DR Worsening March 5, 2021 April 2029
NCT05836194 Recruiting Evaluation of Diabetic Retinopathy Using Ultra-Widefield Fundus Images Compared With Two-Field Fundus Images February 1, 2023 June 30, 2024
NCT02587741 Recruiting Early Phase 1 Comparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens July 2015 July 2025
NCT06321302 Recruiting Phase 2 A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy May 7, 2024 November 11, 2026
NCT05883072 Recruiting Exploring the Effectiveness of AI Generative Models for Diabetic Patients January 5, 2023 December 31, 2026
NCT05902650 Recruiting Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy January 1, 2021 December 31, 2023
NCT05930561 Recruiting Phase 2 4D-150 in Patients With Diabetic Macular Edema August 9, 2023 July 1, 2028
NCT03680794 Recruiting N/A Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies June 27, 2018 February 1, 2025
NCT05138029 Recruiting Phase 3 Study on Precision Treatment of Diabetic Retinopathy Macular Edema Guided by Real-time OCT During Operation November 15, 2021 May 2024
NCT06003751 Recruiting Phase 2 A Study of PER-001 in Participants With Diabetic Retinopathy August 5, 2023 May 31, 2026
NCT03466177 Recruiting Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease March 1, 2018 December 31, 2025
NCT04805541 Recruiting Assessment of EyeCheckup as an Automated Diabetic Retinopathy Screening Tool February 1, 2022 July 2022
NCT06011798 Recruiting Phase 2 Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE) August 23, 2023 June 2025
NCT06343350 Recruiting OPTDR01 Feasibility for Automated Diabetic Retinopathy Detection April 1, 2024 December 30, 2024
NCT05494775 Recruiting N/A Effect of Corona Virus on Intravitreal Injections February 1, 2019 July 30, 2023
NCT06074731 Recruiting Diagnostic Possibilities in Ophthalmological Diseases Using Swept Source Optical Coherence Tomography June 1, 2017 December 2026
NCT04888598 Recruiting Microvascular Changes in OCT-angiography in Type 1 Diabetes Mellitus at the Onset of the Disease and After Optimization of Glycemic Control. June 1, 2021 June 2024
NCT06112691 Recruiting ARTIFICIAL INTELLIGENCE FOR MASS SCREENING OF THE DIABETIC RETINOPATHY IN THE CHERNIVTSI REGION (Pilot Study) February 1, 2022 November 2024
NCT06124586 Recruiting N/A Early Percutaneous Transluminal Angioplasty in Diabetic Foot Syndrome (PTA-DFS) February 1, 2024 November 1, 2028
NCT04935749 Recruiting Epidemiologic Assessment of Diabetic Retinopathy in Egypt Using Ultrawide Field Fundus Photographs July 1, 2021 April 1, 2026
NCT01496625 Recruiting National Eye Institute Biorepository for Retinal Diseases June 18, 2012
NCT03135327 Recruiting N/A Clinical Applications of Advanced Ophthalmic Imaging January 1, 2007 December 31, 2025
NCT03161652 Recruiting Phase 2 Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema May 24, 2017 June 2025
NCT03242031 Recruiting N/A Medico-economic Comparison Between Treatment With Panretinal Photocoagulation by Laser in 1 Session Versus 4 Sessions in Diabetic Retinopathy June 21, 2017 March 2024
NCT05079399 Recruiting Biomarker of Diabetic Retinopathy January 1, 2022 June 30, 2026
NCT06173232 Recruiting Assessment of Retinal Fundus Imaging Camera November 20, 2023 May 2024
NCT03403686 Recruiting Liver X Receptor (LXR) as a Novel Therapeutic Target in Diabetic Retinopathy (DR) January 11, 2018 December 31, 2024
NCT03403699 Recruiting Human iPSC for Repair of Vasodegenerative Vessels in Diabetic Retinopathy January 11, 2018 January 31, 2025
NCT05130385 Recruiting High Resolution Optical Coherence Tomography November 30, 2021 November 30, 2023
NCT06264427 Recruiting N/A Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland July 15, 2022 December 31, 2026
NCT04187443 Recruiting Phase 1 MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema June 2, 2020 January 31, 2024
NCT03713268 Recruiting Intraoperative OCT Guidance of Intraocular Surgery II September 30, 2018 May 31, 2025
NCT04240652 Recruiting The Diabetic Retinopathy Screening, Prevention and Control Program June 5, 2018 June 5, 2040
NCT05566717 Recruiting An Investigator-Initiated Study to Assess the Association of Diabetic Retinopathy Severity Scale (DRSS) With Level of Decreased Corneal Sensitivity July 1, 2022 October 31, 2022
NCT06183476 Recruiting N/A Circadian Amplification in Diabetic Retinopathy March 20, 2024 June 2026
NCT03752840 Recruiting N/A Village-Integrated Eye Worker Trial II April 21, 2019 December 31, 2024
NCT05188703 Recruiting N/A Patient Navigator Intervention for Diabetic Retinopathy July 25, 2022 December 1, 2025
NCT06287645 Recruiting Color Fundus Photograph With Experts Labelling May 12, 2022 June 30, 2026
NCT05615740 Recruiting N/A Prevention of Onset and Transition to an Advanced Form of Diabetic Retinopathy in Children May 2, 2022 December 2025
NCT03571217 Recruiting Shanghai Beixinjing Diabetic Eyes Study October 1, 2014 December 31, 2024
NCT06305416 Recruiting Phase 3 A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema March 30, 2024 April 2025
NCT04496817 Recruiting N/A Enriched Eggs for Retina Health in Type 2 Diabetes July 11, 2022 September 1, 2024
NCT04624737 Recruiting Intelligent Evaluation of Diabetic Retinopathy December 21, 2020 January 21, 2025
NCT05248334 Recruiting Phase 1 A Prospective Study of Ranibizumab in the Treatment of Postoperative Recurrent Vitreous Haemorrhage of Diabetic Retinopathy April 10, 2022 December 30, 2024
NCT05166122 Recruiting N/A Implementation of an Integrated System of Artificial Intelligence and Referral Tracking for Real-time Diabetic Retinopathy Screening January 1, 2022 September 30, 2022
NCT04505618 Recruiting N/A Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease October 1, 2019 September 1, 2025
NCT05752045 Recruiting N/A OphtAI Diagnostic Performance Validation for Automated Screening of Eye Diseases June 28, 2023 March 2024
NCT04547439 Recruiting Phase 2 Sleep, Diabetic Retinopathy and Melatonin February 3, 2021 June 2026
NCT06229379 Recruiting N/A The Effects of a Large Language Model on Clinical Questioning Skills September 1, 2023 June 2024
NCT04594603 Recruiting Changes of Macular Vasculature After Uncomplicated Phacoemulsification Surgery Using Optical Coherence Tomography Angiography April 13, 2021 December 30, 2024
NCT05038020 Terminated Phase 2 A Study to Evaluate the Efficacy of Oral AKST4290 in Participants With Moderately Severe to Severe Diabetic Retinopathy (CAPRI) August 17, 2021 April 19, 2022
NCT00001310 Terminated Tissue Studies of Human Eye Diseases March 5, 1992 September 16, 2015
NCT00248157 Terminated Phase 3 Extension Study of the Long-term Safety and Tolerability of Octreotide Acetate in Patients With Moderately Severe or Severe Non-proliferative Diabetic Retinopathy or Low Risk Proliferative Diabetic Retinopathy November 2005 May 2006
NCT00880139 Terminated Study Investigating the Levels and Effects of Low-grade Inflammation in Diabetic Retinopathy of Type 1 Diabetes June 2009 September 2012
NCT05063734 Terminated Phase 2 A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema. August 27, 2021 June 29, 2022
NCT03635671 Terminated Diabetic Retinopathy and Subclinical Signs of Disease Transition September 1, 2018 July 15, 2019
NCT04991350 Terminated Phase 4 Effect of Ranibizumab Versus Bevacizumab on the Macular Perfusion in Diabetic Macular Edema November 26, 2021 November 1, 2022
NCT02681809 Terminated Phase 2 A Study to Evaluate the Efficacy and Safety of Ocriplasmin in Inducing Total PVD in Subjects With NPDR December 2015 November 18, 2019
NCT02984813 Terminated Phase 1 Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy April 15, 2016 January 15, 2017
NCT00939276 Terminated Phase 3 Macular Edema Incidence/Severity Reduction With Nevanac August 2009 August 2011
NCT01591902 Terminated Phase 4 Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA® June 2012 August 2018
NCT03345901 Terminated Phase 3 PROMINENT-Eye Ancillary Study (Protocol AD) January 15, 2018 April 3, 2019
NCT00701181 Terminated Phase 2 Study Evaluating Efficacy and Safety of PF-04523655 Versus Laser in Subjects With Diabetic Macular Edema June 2008 January 2011
NCT00767884 Terminated Effect of Panretinal Photocoagulation on Optic Nerve Head Topography October 29, 2008 October 17, 2013
NCT00248131 Terminated Phase 3 Extension Study of Long-term Safety and Tolerability of Octreotide Acetate in Patients With Moderately Severe or Severe Non-proliferative Diabetic Retinopathy or Low Risk Proliferative Diabetic Retinopathy November 2005 July 2006
NCT00704652 Terminated Evaluation of Retinal Changes in Systemic Darbepoetin Alpha Treatment in Patients With Diabetes Mellitus May 2008 September 2009
NCT02510885 Terminated N/A SD-OCT Angiography July 2015 March 11, 2019
NCT02875704 Terminated Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic Retinopathy January 3, 2017 September 22, 2022
NCT03794752 Terminated N/A Visual Enhancement Device in Low Vision Patients February 2015 December 28, 2018
NCT02826655 Terminated N/A Adaptive Optics for Ophthalmic Technologies June 2016 June 2016
NCT01375166 Terminated Coupling of Neural Activity and Retinal Blood Flow in Diabetes March 6, 2013 March 6, 2013
NCT00505947 Terminated Phase 3 Treatment of Refractory Diabetic Macular Edema With Infliximab July 2007 December 2008
NCT00211406 Terminated Phase 1 Treatment of Diabetic Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)
NCT01213888 Terminated N/A Trientine Hydrochloride for the Prevention of Macular Edema Associated With Pan-retinal Photocoagulation for Severe Non-proliferative and Proliferative Diabetic Retinopathy November 2010 April 2013
NCT00718614 Terminated N/A Choroidal Blood Flow Changes During Dark/Light Transitions in Patients With Insulin-dependent Diabetes Mellitus (IDDM) June 2007 July 2007
NCT01717937 Terminated Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging February 2013 June 2013
NCT06181227 Terminated Phase 2 A Phase 2 Study of Intravitreal AVD-104 in Diabetic Macular Edema November 30, 2023 April 5, 2024
NCT01168258 Terminated Evaluation of Single Nucleotide Polymorphisms (SNPs) in Patients With and Without Diabetic Macular Edema July 7, 2010 August 7, 2013
NCT00664183 Terminated Phase 2/Phase 3 A Safety and Efficacy Study of Vitreosolve® for Non-Proliferative Diabetic Retinopathy Subjects March 2008
NCT03602989 Unknown status A Multi-center Study on the Artificial Intelligence Enabled Diabetic Retinopathy Screening Based on Fundus Images July 5, 2018 August 31, 2019
NCT03631108 Unknown status Feasibility Study and Preliminary Application Study on Iris OCTA October 2018 June 2019
NCT00677664 Unknown status Phase 4 Effects of Copaxone in the Retinal Function in Diabetic Patients After Panphotocoagulation July 2006 September 2008
NCT00695682 Unknown status Phase 1 Intravitreal Infliximab for Diabetic Macular Edema (DME) and Choroidal Neovascularization (CNV) June 2008 December 2008
NCT00703235 Unknown status Phase 2/Phase 3 Intravitreal Bevacizumab for Diabetic Macular Edema
NCT05310916 Unknown status Phase 3 Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients June 6, 2022 November 2023
NCT00498147 Unknown status Determining Rates of Cardiovascular Complications Among Patients of a Managed Diabetes Care Program July 2007 July 2010
NCT03751501 Unknown status N/A Targeted Laser in Diabetic Macular Edema November 22, 2018 October 24, 2021
NCT00849537 Unknown status Phase 1/Phase 2 The Effect of Intravitral Injection of Triamcinolone Combined With Cataract Surgery (Phacoemulsification) on Diabetic Macular Edema and Diabetic Retinopathy April 2008 April 2009
NCT00855608 Unknown status Phase 1 Intravitreal Adalimumab in Refractory Diabetic Retinopathy, Choroidal Neovascularization or Uveitis: A Pilot Study March 2009 March 2013
NCT03765112 Unknown status N/A Macular Involvement in Diabetic Retinopathy Evaluated With Swept-Source OCT September 20, 2018 March 31, 2023
NCT03769948 Unknown status Clinical Decision Support Algorithm to Predict Diabetic Retinopathy February 2022 July 2023
NCT05333055 Unknown status Aqueous Biomarker Levels in Diabetic Retinopathy and Diabetic Macular Edema April 11, 2022 August 2023
NCT03823092 Unknown status Polarization Perception in Health and Disease. Testing a New Sight Test November 9, 2017 July 2019
NCT00908778 Unknown status Phase 3 A Safety and Efficacy Study of Vitreosolve® for Non-Proliferative Diabetic Retinopathy Subjects October 2008
NCT00931125 Unknown status Phase 2 Safety and Efficacy of Intravitreal Ranibizumab as a Preoperative Adjunct Treatment Before Vitrectomy Surgery in Proliferative Diabetic Retinopathy (PDR) Compared to Vitrectomy Alone March 2009 December 2013
NCT03863535 Unknown status N/A PRP vs PRP+IVC for Severe nPDR January 18, 2019 September 30, 2021
NCT01023113 Unknown status N/A To Compare Visual Field Impairment in Conventional Double Frequency Nd: YAG Panretinal Photocoagulation With PASCAL Panretinal Photocoagulation September 2009 March 2010
NCT03899623 Unknown status Multi-modal Imaging and Artificial Intelligence Diagnostic System for Multi-level Clinical Application April 23, 2018 December 31, 2019
NCT03903042 Unknown status Comparison of Aurora Fundus Camera With Traditional Camera in Diabetic Retinopathy With Visual Artificial Intelligence November 1, 2018 May 2019
NCT05386160 Unknown status Phase 4 Phacoemulsification Combined With Intravitreal Injection of Ranibizumab Prevent Postoperative Capillary Non-perfusion Zone Progress in Non-proliferative Diabetic Retinopathy July 1, 2022 March 1, 2023
NCT03911323 Unknown status Real-world Diagnostic Effectiveness of Artificial Intelligence Algorithm in Diabetic Retinopathy Screening October 1, 2018 October 1, 2020
NCT05391659 Unknown status N/A E-CLAIR: Efficiency and Cost-effectiveness of Artificial Intelligence Based Diabetic Retinopathy Screening in Flanders June 17, 2021 December 1, 2022
NCT05415826 Unknown status N/A Ozurdex in Reducing PVR After Vitreotomy in PDR June 15, 2022 September 15, 2022
NCT03970161 Unknown status N/A Evaluation of Early Retinal Nerve Injury in Type 2 Diabetes Patients Without Diabetic Retinopathy May 29, 2019 June 1, 2021
NCT05429229 Unknown status Phase 2 Effect of Topical Antioxidants in Dry Eye Disease and Diabetic Retinopathy November 1, 2021 January 31, 2024
NCT05452993 Unknown status N/A Screening for Diabetic Retinopathy in Pharmacies With Artificial Intelligence Enhanced Retinophotography September 2022 January 2024
NCT01298245 Unknown status Genetic Association of Diabetic Retinopathy-1 February 2011 December 2012
NCT01304225 Unknown status Phase 3 Panretinal Photocoagulation for Diabetic Retinopathy With PASCAL Laser September 2010 March 2013
NCT04030611 Unknown status The Sensitivity of Traditional Chinese Medical Diagnostic Tools for Diabetic Retinopathy Diabetic retinopathy-a Pilot Study January 1, 2019 October 10, 2019
NCT04038125 Unknown status Phase 4 Increase in Capillary Plexus Density Level Following the Use of Ozurdex for the Treatment of DME August 22, 2019 August 2021
NCT04101604 Unknown status Biomarkers of Common Eye Diseases September 26, 2019 October 1, 2021
NCT01382498 Unknown status Phase 4 Effect of Doxium on High Sensitivity CRP and Endothelin-1 Serum Levels in Patients With Diabetic Retinopathy November 2009
NCT04117022 Unknown status N/A Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG September 1, 2019 December 1, 2022
NCT04120077 Unknown status N/A Combined Effects of Diabetes Self-Management Education and Nutritional Supplementation on Visual Function and Retinopathy January 1, 2020 January 1, 2022
NCT04128150 Unknown status High Resolution Retina Imaging January 17, 2018 January 30, 2024
NCT01487629 Unknown status Phase 2 Bevacizumab Versus Ranibizumab for the Treatment of Diabetic Macular Edema April 2010 September 2012
NCT04140201 Unknown status Phase 4 Effect of Lipid Lowering Agents on Diabetic Retinopathy and Cardiovascular Risk of Diabetic Patients February 2020 August 2020
NCT01517490 Unknown status Retinal Adaptation to Intensified Insulin Therapy and Bariatric Surgery in Patients With Diabetes August 2011
NCT04215445 Unknown status Phase 4 Effect of SGLT2 Inhibition on OCT-A Parameters in Diabetic CKD December 1, 2019 August 2020
NCT00476918 Unknown status Phase 1 Intravitreal Triamcinolone Acetonide for Diabetic Macular Edema July 2006 December 2007
NCT04283162 Unknown status Phase 4 Using Calcium Dobesilate to Treat Chinese Patients With Mild to Moderate Non-proliferative Diabetic Retinopathy March 1, 2020 January 31, 2022
NCT00229918 Unknown status Phase 2 PST/Laser v. Laser Alone for CSME September 2005 September 2006
NCT01824043 Unknown status Phase 4 Use of Intravitreal Ranibizumab in the Treatment of Vitreous Hemorrhage March 2013 December 2013
NCT04448496 Unknown status Phase 4 Prospective Trial of Dexamethasone implAnt for Treatment Naïve diabeTic Macular Edema June 22, 2020 December 31, 2021
NCT01879501 Unknown status N/A Living Successfully With Chronic Eye Diseases January 2013 January 2015
NCT04488887 Unknown status OCTA Metrics Repeatability and Reproducibility in Different Disorders August 1, 2020 July 31, 2021
NCT04499768 Unknown status A Longitudinal Study of Choroidal Changes After Cataract Surgery in Eyes With Diabetic Retinopathy June 1, 2018 December 30, 2020
NCT00407849 Unknown status Phase 1/Phase 2 Intravitreal Triamcinolone Acetonide for Treatment of Refractory Diffuse Diabetic Macular Edema October 2006 August 2008
NCT02026843 Unknown status Analysis of Angiogenic Factor Levels in Eyes With Diabetic Retinopathy April 2012 April 2022
NCT02063321 Unknown status Reading Center - Occurence of Diabetic Macular Edema in Patients With Diabetes Mellitus in Slovak Republic December 2012 December 2015
NCT00524875 Unknown status N/A Effect of Intravitreal Bevacizumab on Early Post-Vitrectomy Hemorrhage in Diabetic Patients January 2007 September 2007
NCT04552600 Unknown status Phase 1/Phase 2 Study to Evaluate Clinical Efficacy and Safety of Nuvastatic™ - C5OSEW5050ESA in Diabetic Retinopathy. September 1, 2019 August 31, 2021
NCT02227745 Unknown status Efficacy of Dorzolamide as an Adjuvant After Focal Photocoagulation in Clinically Significant Macular Edema January 2014 December 2015
NCT04627272 Unknown status N/A AutoDx-DR Prospective Clinical Validation Study Protocol December 1, 2020 July 31, 2021
NCT04631653 Unknown status N/A Verisee Software for Diabetic Retinopathy Screening December 1, 2020 December 31, 2023
NCT02337972 Unknown status N/A Conjunctival Flora Patterns After Serial Intravitreal Injections in Diabetic Patients January 2015 January 2016
NCT02353923 Unknown status N/A OcuStem Nutritional Supplement in Diabetic Patients With Mild to Moderate Non-proliferative Retinopathy September 2014 September 2016
NCT04648618 Unknown status Obstructive Sleep Apnea and Diabetic Macular Edema Inflammatory Mediators January 1, 2018 December 31, 2020
NCT04660006 Unknown status Diabetic Retinopathy and OCT-A Changes Post-cataract Surgery May 27, 2019 July 2021
NCT02409511 Unknown status Microalbuminuria as a Cardiovascular Risk Factor (PRECISED Substudy) January 2016 April 2018
NCT04665102 Unknown status Pilot Study on Deep Learning in the Eye February 1, 2021 December 1, 2022
NCT04668703 Unknown status N/A Prophylactic Effect of Conbercept Intravitreal Injection at the Conclusion of Cataract Surgery for Diabetic Macular Edema January 1, 2021 January 1, 2022
NCT02486484 Unknown status Phase 2 Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection March 2015 December 2019
NCT04682054 Unknown status N/A Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics January 15, 2021 December 31, 2021
NCT00370721 Unknown status Phase 3 Intravitreal Bevacizumab for Management of Active Progressive Proliferative Diabetic Retinopathy (PDR) March 2006
NCT04742829 Unknown status N/A Effects of a Therapy With INTRAVIT® Tablets in Patients With Diabetic Retinopathy October 1, 2020 March 8, 2021
NCT02871817 Unknown status A Comparison of the Checkup Vision Assessment System to Standard Vision Assessment Tools July 2016 March 2018
NCT02956759 Unknown status N/A Early Laser Treatment for Diabetic Eye Disease in China : A Pilot Randomized Trial October 2016 October 2023
NCT03006081 Unknown status Phase 2 The Efficacy of Intravitreal Aflibercept Injection in Improvement of Retinal Nonperfusion in Diabetic Retinopathy May 2016 June 2018
NCT03094819 Unknown status N/A PROTECT2: Diabetes Care - Eye Exam March 17, 2016 December 31, 2023
NCT03264976 Unknown status Role of the Serum Exosomal miRNA in Diabetic Retinopathy (DR) July 1, 2018 July 1, 2023
NCT03343730 Unknown status N/A RetinaVue Diabetic Screening February 27, 2018 October 1, 2018
NCT03422965 Unknown status N/A Perifoveal Vascular Network Assessed by OCT-Angiography in Type I Diabetes Mellitus May 8, 2017 May 31, 2021
NCT03452657 Unknown status Phase 3 Multicenter Clinical Study of Anti-VEGF Treatment on High Risk Diabetic Retinopathy (DR) April 2018 June 2020
NCT05140304 Unknown status N/A Analysis of FAZ in Diabetic Retinopathy Using OCT Angiography November 30, 2021 November 2022
NCT03571139 Unknown status Detecting the Influence of Cataract Surgery on the Development of Diabetic Retinopathy in Patients With Diabetes Mellitus Type 2 With and Without Diabetic Retinopathy Using OCT Angiography June 1, 2018 January 2019
NCT03572699 Unknown status Simple, Mobile-based Artificial Intelligence AlgoRithms in the Detection of Diabetic ReTinopathy (SMART) Study July 11, 2018 October 2018
NCT03579797 Unknown status Shanghai Diabetic Eye Study in Diabetics January 1, 2015 December 31, 2018
NCT03594591 Unknown status Changes in the Retinal and Carotid Microcirculation After Restoring Normoglycemia in Patients With Type 2 Diabetes January 2, 2018 January 1, 2020
NCT00407108 Withdrawn Phase 3 Perfluorocarbon Perfused Vitrectomy and 3D Vitrectomy System in Advanced Diabetic Retinopathy March 2006 June 2006
NCT04334499 Withdrawn Mitochondrial DNA in Vitreous Fluid and Blood in Patients With Eye Disease or Ocular Trauma. February 21, 2020 December 7, 2022
NCT00457470 Withdrawn Phase 2 A Phase 2 Study Exploring The Safety And Efficacy Of Novel Drug Treatment In Subjects With Diabetic Macular Edema (DME) June 2007
NCT03603990 Withdrawn N/A Effect of Vitrectomy on the Evolution of Refractory Diabetic Macular Edema September 1, 2018 March 1, 2020
NCT00496405 Withdrawn Phase 4 Unilateral Bevacizumab for Bilateral Diabetic Macular Edema April 2007 October 2007
NCT03399825 Withdrawn Optical Coherence Tomography Angiography (OCT-A) in Children (≥ 6 <14 Years of Age) January 2018 March 1, 2018
NCT02812030 Withdrawn Aflibercept for Retinopathy in the Real World September 2016 August 2018
NCT00347698 Withdrawn Phase 2/Phase 3 Intravitreal Bevacizumab vs Photocoagulation for Proliferative Diabetic Retinopathy March 2006 August 2007
NCT00853424 Withdrawn Phase 3 A Comparison of Islet Cell Transplantation With Medical Therapy for the Treatment of Diabetic Eye Disease December 2009 December 2010
NCT02349516 Withdrawn Phase 2 Squalamine Lactate Eye Drops in Combination With Ranibizumab in Patients With Diabetic Macular Edema (DME) February 2015 September 2015
Disase is a (Disease Ontology)
DOID:2462
Cross Reference ID (Disease Ontology)
ICD9CM:362.0
Cross Reference ID (Disease Ontology)
MESH:D003930
Cross Reference ID (Disease Ontology)
NCI:C34538
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:154678005
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0011884
Exact Synonym (Disease Ontology)
Retinal abnormality - diabetes-related
MeSH unique ID (MeSH (Medical Subject Headings))
D003930