malaria

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Information
Disease name
malaria
Disease ID
DOID:12365
Description
"A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle." [url:http\://en.wikipedia.org/wiki/Malaria, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=malaria]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03967054 Active, not recruiting Phase 3 Repeat Ivermectin Mass Drug Administrations for MALaria Control II July 13, 2019 August 1, 2024
NCT05736679 Active, not recruiting N/A EaveTubes for Vector Control March 23, 2023 December 2025
NCT06392152 Active, not recruiting N/A Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar July 1, 2019 December 31, 2024
NCT05155579 Active, not recruiting Phase 1 Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines May 14, 2022 May 2025
NCT04622241 Active, not recruiting N/A Uganda Housing Modification Study January 29, 2021 July 2023
NCT05567016 Active, not recruiting N/A CHILD (Child Health and Infection With Low Density) Malaria July 18, 2023 November 28, 2025
NCT05343312 Active, not recruiting Phase 4 In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique March 16, 2022 July 30, 2024
NCT05581641 Active, not recruiting Phase 1 Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria December 15, 2022 September 2024
NCT04704674 Active, not recruiting Community Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District, Bong County, Liberia September 30, 2021 February 28, 2025
NCT05041556 Active, not recruiting Strengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine April 1, 2021 June 30, 2024
NCT04978272 Active, not recruiting Phase 3 Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) February 8, 2022 August 31, 2026
NCT05323721 Active, not recruiting Phase 4 Effectiveness and Chemoprevention Efficacy of Implementing Seasonal Malaria Chemoprevention in Karamoja Region, Uganda June 1, 2022 December 1, 2023
NCT05471544 Active, not recruiting Phase 3 Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan July 18, 2022 December 31, 2024
NCT05385510 Active, not recruiting Phase 1 Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV January 10, 2023 September 2025
NCT05304611 Active, not recruiting Phase 2 Anti-malaria MAb in Malian Children March 18, 2022 April 2024
NCT03931473 Active, not recruiting N/A Efficacy of Two Dual Active Ingredient Long Lasting Insecticidal Nets for Control of Malaria Transmitted by Pyrethroid Resistant Vectors in Benin June 1, 2020 September 2023
NCT06155448 Active, not recruiting N/A Perennial Malaria Chemoprevention (PMC) Effect Study August 8, 2023 December 2026
NCT04419766 Active, not recruiting N/A Evaluation of IR3535 as a Spatial Repellent for Malaria Control. April 28, 2021 December 30, 2024
NCT04336189 Active, not recruiting Phase 3 Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda December 28, 2020 June 1, 2024
NCT04969913 Active, not recruiting Community Dynamics of Malaria Transmission in Humans and Mosquitoes at Maferinyah Sub-Prefecture, Guinea March 7, 2022 February 15, 2025
NCT05478954 Active, not recruiting Phase 4 Chemoprevention Efficacy Study in Burkina Faso July 15, 2022 December 1, 2023
NCT04966702 Active, not recruiting Phase 3 Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA) March 17, 2022 October 31, 2024
NCT06153862 Active, not recruiting N/A Africa Ready Malaria Screening September 23, 2022 September 2025
NCT04079621 Active, not recruiting Phase 4 Short Course Radical Cure of P. Vivax Malaria in Nepal October 27, 2021 March 31, 2024
NCT06225297 Active, not recruiting Phase 4 Evaluation of a Package of Interventions to Reduce the Burden of Malaria in the Urban Daaras of Touba, Senegal January 19, 2024 February 2025
NCT00131235 Active, not recruiting Phase 3 Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth December 2003 December 31, 2025
NCT04800055 Active, not recruiting N/A Attractive Targeted Sugar Bait Phase III Trial in Zambia December 1, 2020 December 31, 2023
NCT03689036 Active, not recruiting Transmission Dynamics of Residual and Re-emerging Malaria in the Amazon: Defining a Roadmap to Malaria Elimination April 2, 2018 July 31, 2024
NCT05391230 Active, not recruiting N/A Permethrin-treated Baby-wraps for the Prevention of Malaria in Children June 3, 2022 June 2025
NCT05186363 Active, not recruiting Phase 4 Effectiveness of Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Type Two Hybrid Implementation Study January 8, 2022 December 1, 2023
NCT04704830 Active, not recruiting Phase 3 R21/Matrix-M in African Children Against Clinical Malaria April 29, 2021 March 2026
NCT04650815 Active, not recruiting Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso June 10, 2021 December 30, 2024
NCT02414399 Active, not recruiting Phase 4 Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children June 28, 2016 December 28, 2025
NCT00158561 Completed Phase 3 Chlorproguanil/Dapsone Compared With Chloroquine and SP for Vivax Malaria February 2004 March 2006
NCT00158574 Completed Phase 2/Phase 3 Kilimanjaro IPTi Drug Options Trial January 2005 June 2008
NCT00158587 Completed Phase 3 Eight Week Primaquine Regimen for the Treatment of Vivax Malaria April 2004 March 2007
NCT00164255 Completed Phase 4 Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy January 2003 June 2009
NCT00167739 Completed Phase 4 Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine April 2003 February 2004
NCT00167843 Completed Phase 4 Reducing the Effects of Malaria in Children by Administering Repeated Preventive Doses December 2002 March 2007
NCT00169078 Completed N/A Impact of Insecticide-treated Curtains on Antimalarial Drug Resistance July 2002 December 2002
NCT00169117 Completed N/A A Stitch in Time May Save Lives: Turning Poor Bednets Into Good Ones June 2002 December 2002
NCT00197028 Completed Phase 2 Examine Safety and Immune Responses of GSK 257049 Vaccine When Administered to Infants Living in a Malaria-endemic Region August 23, 2005 December 27, 2007
NCT00197041 Completed Phase 2 A Study to Evaluate the Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Malaria Vaccine RTS,S/AS02A, When Administered to Children Aged 1 to 4 Years Living in a Malaria-endemic Region of Mozambique. July 2003 April 2005
NCT00197067 Completed Phase 1 A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Candidate Vaccines RTS,S/AS02D (0.5 mL Dose) and RTS,S/AS02A (0.25 mL Dose) Administered IM According to a 0, 1, 2 Month Vaccination Schedule in Children Aged 3 to 5 Years Living in a Malaria-endemic Region of Mozambique. March 15, 2004 April 26, 2005
NCT00203736 Completed N/A A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria January 2003 October 2003
NCT00203801 Completed N/A Combination Antimalarials in Uncomplicated Malaria January 2002 July 2005
NCT00203814 Completed N/A A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria January 2004 March 2005
NCT00206739 Completed Phase 4 Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants January 2003 September 2005
NCT00214643 Completed Phase 3 Efficacy of Fosmidomycin-Clindamycin for Treating Malaria in Gabonese Children June 2005 July 2006
NCT00215267 Completed N/A The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda September 2005 October 2007
NCT00217451 Completed Phase 2 Treatment of Malaria in Gabon With Fosmidomycin-Clindamycin June 2002 March 2003
NCT00225368 Completed N/A Effects of Insecticide Treated Bednets on Child Morbidity and Mortality
NCT00229775 Completed N/A Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines July 2003 July 2008
NCT00231452 Completed N/A Age of Exposure and Immunity to Malaria in Infants September 2005 March 2009
NCT00243737 Completed Phase 2 Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria October 2005 April 2006
NCT00258024 Completed N/A Control of Pregnancy Associated Malaria With Intermittent Preventive Treatment November 2005 October 2007
NCT00261222 Completed Phase 2 Efficacy of Amodiaquine in the Treatment of Uncomplicated Falciparum Malaria in Young Children of Burkina Faso September 2005 November 2005
NCT00266058 Completed Phase 1 Drug Interaction Study Between Antimalarial and Anti-HIV Medications December 2005 November 2010
NCT00269178 Completed Phase 3 Cluster Randomized Trial of Peer Health Education in Malaria in The Gambia August 2003 October 2004
NCT00274235 Completed Phase 3 Intermittent Preventive Treatment During Pregnancy in Benin July 2005 April 2008
NCT00285662 Completed N/A Intermittent Preventive Treatment (IPTi) for the Prevention of Malaria and Anaemia in PNG Infants June 2006 May 2010
NCT00287300 Completed N/A Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women September 2003 August 2005
NCT00289185 Completed Phase 2 Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants September 27, 2006 January 15, 2009
NCT00292929 Completed Phase 1 Study of the Safety of Intravenous Artesunate October 2006
NCT00292942 Completed Phase 1 Study of the Safety of Intravenous Artesunate June 12, 2006 January 2008
NCT00294580 Completed Phase 4 Early Childhood Malaria Prevention With Maloprim in The Gambia April 1982 September 2001
NCT00297882 Completed Phase 3 Artemisinin-Based Combination Therapy: Clinical Trials in Cameroon July 2006 July 2009
NCT00298610 Completed Phase 2 Safety and Efficacy Study of IV Artesunate to Treat Malaria March 2006 October 2007
NCT00307021 Completed Phase 2 Double-blind Study of Safety and Immunogenicity of Two Candidate Malaria Vaccines in Gabonese Children April 7, 2006 August 22, 2007
NCT00308061 Completed Phase 1 Safety Study of Candidate Malaria Vaccine FMP1/AS02A in Healthy Adults in Bandiagara, Mali July 2003 July 2005
NCT00312702 Completed Phase 1/Phase 2 Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America April 2006 April 2007
NCT00316329 Completed Phase 3 ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria March 2006
NCT00317590 Completed Phase 4 Effectiveness and Cost-Effectiveness of a Rapid Diagnostic Test for Malaria April 2006 October 2006
NCT00320658 Completed Phase 1 Safety of and Immune Response to a Malaria Vaccine (MSP1 42-C1) With or Without CPG 7909 Adjuvant March 2006 July 2007
NCT00323375 Completed Phase 1 Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With Chloroquine August 1, 1999 August 31, 2005
NCT00323622 Completed Phase 2 Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine April 2005 May 2007
NCT00327964 Completed Rapid Diagnostic Tests (RDTs) for Malaria in Kampala, Uganda October 2005 May 2006
NCT00329134 Completed Phase 2 Investigation of the Efficacy of Quinine Sulphate Administered Via Taste-Masked Pellets to Children With Falciparum Malaria July 2006 May 2007
NCT00336375 Completed Phase 4 Treatment of Uncomplicated Childhood Malaria in Tanzania by Artemether+Lumefantrine - Efficacy and Genotyping June 2006 July 2006
NCT00336388 Completed N/A Use of Rapid Diagnostic Tests for Malaria Case Management in Kenya July 2006 September 2006
NCT00341003 Completed Severe Malaria and Anti-malarial Drug Resistance in Cambodia July 22, 2005 January 14, 2011
NCT00341250 Completed Phase 1/Phase 2 Malaria Vaccine in Children in Mali January 19, 2006 December 8, 2006
NCT00341666 Completed Immune Response Regulation in People Infected Concurrently With Malarial and Filarial Parasites April 3, 2006 July 15, 2011
NCT00342043 Completed Examination of Protective Factors Against Severe Malaria August 2, 2005 April 16, 2009
NCT00346346 Completed Analysis of the Immune Response to the Malaria Parasite in Mali, West Africa April 17, 2006 January 23, 2013
NCT00347113 Completed N/A Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania July 2006 January 2011
NCT00349713 Completed Phase 1 FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, Mali November 2004 December 2006
NCT00351013 Completed Phase 4 The Use of Homeopathic-Based Treatment Approaches to Reduce the Prevalence of Malaria in Depressed Communities June 2006 June 2007
NCT00354380 Completed Phase 2 Safety and Efficacy of Methylene Blue Combined With Artesunate or Amodiaquine for Malaria Treatment in Children of Burkina Faso: a Pilot Study September 2006 November 2006
NCT00355225 Completed N/A Community-Effectiveness of the Distribution of Insecticide-Treated Bed Nets Through Social Marketing Antenatal Care Services in Malaria Control in Rural Burkina Faso
NCT00356824 Completed Relationship Between HIV and Malaria in Ugandan Children November 2005 May 2010
NCT00360230 Completed Phase 2 Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian Children August 30, 2006 May 30, 2008
NCT00367380 Completed Phase 2 Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers December 2006 March 2007
NCT00367653 Completed Phase 3 Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria. November 2006 September 2007
NCT00368810 Completed Study of Factors Involved in Resistance to Severe Malaria February 21, 2006 November 30, 2006
NCT00372684 Completed PALUREA: Severe Imported Malaria in Adults September 2006 March 2010
NCT00373607 Completed Phase 3 Efficacy and Safety of Dihydroartemisinin/Piperaquine (Artekin®) for the Treatment of Uncomplicated Malaria in Peru July 2003 July 2005
NCT00374998 Completed Phase 1 Safety and Immunogenicity Study of the Malaria Vaccines FP9 PP and MVA PP April 2006 January 2007
NCT00375128 Completed Phase 1/Phase 2 Sporozoite Challenge of Polyprotein Vaccinees September 2006 April 2007
NCT00376155 Completed Phase 4 Comparison of Two Strategies for the Delivery of IPTc May 2006 February 2007
NCT00378625 Completed Phase 3 Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in Colombia April 2000 March 2006
NCT00380146 Completed N/A Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-pyrimethamine Intermittent Presumptive Treatment in Pregnant Women September 2006 March 2008
NCT00380393 Completed Phase 2 Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children. January 3, 2007 November 11, 2008
NCT00384267 Completed Congenital and Neonatal Malaria in Mali October 2006 April 2009
NCT00385047 Completed Phase 1/Phase 2 A Study to Determine Whether 2 Investigational Malaria Vaccines Are Safe, Protective Against Malaria in Adults September 2006 September 2007
NCT00386503 Completed Phase 1 Bioavailability of the Fixed Combination of Amodiaquine and Artesunate Under Fed & Fasted Conditions June 2006
NCT00386763 Completed Phase 3 Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria. August 2006 March 2007
NCT00393679 Completed Phase 3 Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children July 2007 December 2009
NCT00399074 Completed Phase 3 Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia October 2006 February 2007
NCT00408668 Completed Phase 1/Phase 2 Efficacy of Combined PEV3A Virosomal Vaccine and FP9-MVA ME-TRAP Prime Boost Regimen August 2005 February 2006
NCT00414336 Completed Phase 1 Phase I Study of Safety and Immunogenicity of AMA1-C1Alhydrogel + CPG 7909 Vaccine for Malaria December 15, 2006 December 15, 2006
NCT00414479 Completed Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment July 2006 January 2010
NCT00421473 Completed Phase 4 Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients March 2007 December 2008
NCT00422084 Completed Phase 3 Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients January 2007 May 2008
NCT00425763 Completed Phase 4 Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria May 2007 August 2007
NCT00427167 Completed Phase 1 Phase I Study of AMA1-C1/Alhydrogel® (Registered Trademark) + CPG 7909 Malaria Vaccine January 23, 2007 November 5, 2008
NCT00432367 Completed Phase 3 Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy February 2007 September 2009
NCT00436007 Completed Phase 2 Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen April 30, 2007 October 7, 2009
NCT00440999 Completed Phase 3 Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria March 2007 September 2008
NCT00443131 Completed Phase 2 Characterisation of the Immune Responses of 2 Experimental Malaria Vaccines March 26, 2007 July 13, 2007
NCT00444106 Completed Phase 4 Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function May 2007 November 2008
NCT00445796 Completed Phase 4 Arsucam® (Artesunate + Amiodaquine) Efficacy and TOLerance June 2005
NCT00451139 Completed Phase 4 Ototoxicity of Artemether / Lumefantrine (Coartem) and Other Antimalarials
NCT00451269 Completed Evaluation of Rapid Diagnosis Tests in Imported Malaria April 2007 January 2010
NCT00452907 Completed Phase 4 ACT MALI: Treatment of Malaria Based on Combination Therapies July 2005 June 2007
NCT00454961 Completed Phase 4 Effectiveness of Artemether-Lumefantrine for Malaria Treatment of Children at Community Level in Tanzania April 2007
NCT00455494 Completed Phase 1 Food-Effect Bioavailability Study of AQ-13, a Candidate Antimalarial January 2005 December 2006
NCT00461578 Completed N/A Tolerability and Efficacy of CD+A Compared to AQ+SP for the Treatment of P.Falciparum Malaria in Rwandan Children April 2005 October 2006
NCT00465777 Completed N/A Improved Management and in-Hospital Mortality December 2004 February 2006
NCT00466557 Completed Plasmodium Resistance in A. Gambiae June 2007
NCT00471302 Completed Normal Immunological Parameters Among Healthy Volunteers in Kambila, Mali August 1, 2007 May 23, 2022
NCT00471666 Completed Medical Implications of Coinfection With Malaria and Filariasis Parasites May 7, 2007 January 31, 2012
NCT00487916 Completed Phase 1 Phase 1 Study of the Safety, Reactogenicity, and Immunogenicity of AMA1-C1/ISA 720: Blood Stage Vaccine for Plasmodium Falciparum June 13, 2007 February 5, 2009
NCT00489619 Completed Safe Pregnancy by Infectious Disease Control April 2004 March 2005
NCT00493922 Completed Phase 4 Trial of Rapid Diagnostic Tests in Rural Ghana July 2007 June 2009
NCT00495508 Completed Phase 4 Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy October 2006 June 2009
NCT00499876 Completed N/A The Effect of Malaria on Disease Progression of HIV/AIDS October 2007 December 2009
NCT00510679 Completed N/A Study of Post-Training Supports for Health Workers in Benin July 1999 October 2004
NCT00513500 Completed N/A Zambia Integrated Management of Malaria and Pneumonia Study June 2007 September 2009
NCT00519467 Completed Phase 2 Safety and Efficacy Dose of Artesunate Used in Combination With LAPDAP Treatment of Uncomplicated Falciparum Malaria June 2003 February 2005
NCT00522132 Completed Phase 2 Phase II Artesunate Study in Severe Malaria September 2007 December 2008
NCT00527163 Completed Role of Nitric Oxide in Malaria September 4, 2007 March 30, 2015
NCT00527800 Completed Phase 3 Interactions Between HIV and Malaria in African Children August 2007 March 2013
NCT00529620 Completed Phase 3 Three Alternative Drug Regimens for Malaria Seasonal Preventive Treatment in Senegal September 2007 December 2007
NCT00538382 Completed Phase 1 Study of Pharmacokinetics and Pharmacodynamics of Artesunate in Pregnant Women in the Democratic Republic of Congo May 2007 December 2008
NCT00540410 Completed Phase 4 Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks September 2007 February 2009
NCT00541385 Completed Phase 3 Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients October 2007 November 2008
NCT00544024 Completed Mefloquine Bioequivalence Among 3 Commercially Available Tablets. March 2004 March 2007
NCT00545935 Completed Phase 2 Safety and Efficacy of Methylene Blue Combined With Amodiaquine or Artesunate for Malaria Treatment in Children of Burkina Faso July 2007 October 2007
NCT00549003 Completed Phase 4 Efficacy and Cost Effectiveness of Malaria Diagnosis Procedures and the Rational Use of ACT in Zanzibar February 2005 August 2005
NCT00550160 Completed Phase 4 The Synergistic Effects of Home-management and Intermittent Preventive Treatment of Malaria in Children April 2007 October 2008
NCT00561899 Completed Phase 2/Phase 3 Comparison of Three Drug Combinations for Intermittent Treatment of Malaria in Children August 2007 June 2008
NCT00563914 Completed Phase 1/Phase 2 A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria October 2007 November 2008
NCT00623155 Completed N/A Seasonal Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine in Children in Mali July 2002 January 2004
NCT00623857 Completed Phase 3 Micronutrients and Child Health Study March 2008 March 2009
NCT00639873 Completed N/A Artemisinin Resistance in Bangladesh June 2008 November 2009
NCT00663546 Completed Malaria Studies in Cambodia March 24, 2008 December 5, 2013
NCT00666380 Completed Phase 1 A Study to Determine the Effects of an Investigational Malaria Vaccine Given to Adults Living in the United States and Thereafter to Adults Living in Kenya April 2008 June 2009
NCT00669084 Completed Innate and Acquired Resistance to Plasmodium Falciparum Malaria in Mali April 21, 2008 November 19, 2013
NCT00673166 Completed N/A Evaluation of Local Mechanisms for Staff Motivation to Reduce Hospital Mortality January 2008 December 2008
NCT00675064 Completed Phase 1 Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects May 2, 2008 October 12, 2008
NCT00680732 Completed Phase 4 Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component June 2003 October 2006
NCT00682630 Completed Phase 1 Bioequivalence Trial of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet September 2007 September 2008
NCT00687895 Completed Phase 4 Improved Clinical and Microscopy Diagnosis at Primary Health Care in Tanzania July 2003 March 2004
NCT00694694 Completed Phase 3 Azithromycin + Artesunate v Artemether-lumefantrine in Uncomplicated Malaria. June 2008 February 2009
NCT00697892 Completed Phase 1 Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations July 2005 December 2010
NCT00699920 Completed Phase 4 Cohort Study in Uganda Comparing Artesunate + Amiodaquine (Coarsucam) Versus Artemether + Lumenfantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks June 2008 June 2010
NCT00716599 Completed N/A Training in Fever Case Management With Rapid Diagnostic Tests (RDTs) for Malaria in Uganda January 2008 July 2008
NCT00719602 Completed Early Phase 1 Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART August 2009 August 2013
NCT00720811 Completed N/A Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs October 2009 January 2012
NCT00738946 Completed N/A A Trial of the Combined Impact of Intermittent Preventive Treatment and Insecticide Treated Bednets in Reducing Morbidity From Malaria in African Children August 2008 December 2009
NCT00740090 Completed Phase 1 Malaria Vaccine for Children in Mali August 11, 2008
NCT00761020 Completed N/A Merozoite Surface Protein 1 Antibody Response in Asymptomatic Human Malaria Infection September 2008 December 2009
NCT00766662 Completed N/A Intermittent Preventive Treatment in Infant in Mali October 2006 December 2007
NCT00772642 Completed Immune Parameters in the Cord Blood of Newborns Exposed to Malaria in the Womb October 8, 2008 September 10, 2010
NCT00790881 Completed Phase 4 Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected Adults October 2008 December 2009
NCT00791531 Completed Phase 1 Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers March 2009 August 2009
NCT00808951 Completed Phase 4 In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso December 2008 February 2011
NCT00811421 Completed N/A Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy September 2009 December 2013
NCT00819858 Completed N/A Effect of Ready to Use Therapeutic Food (RUTF) Supplement After an Episode of Malaria Falciparum on Weight January 2009 March 2009
NCT00832754 Completed Phase 4 Restricting the Use of Artesunate Plus Amodiaquine Combination Therapy to Malaria Cases Confirmed by a Dipstick Test: A Cluster Randomised Control Trial March 2009 December 2012
NCT00840502 Completed Ultrasound Study in Pregnant Women With Malaria February 10, 2009 February 2018
NCT00844207 Completed Phase 1 A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine February 2009 April 2009
NCT00850655 Completed Genetic Association Mapping of Malaria Resistance in Anopheles Gambiae March 2008 March 2015
NCT00852371 Completed Phase 3 Intermittent Preventive Treatment of Malaria in Schoolchildren February 2008 June 2008
NCT00853281 Completed N/A A Cluster Randomized Trial to Evaluate Long Lasting Insecticidal Hammocks to Prevent Forest Malaria in Vietnam March 2004 June 2007
NCT00857077 Completed N/A Intermittent Preventive Treatment for Malaria in Infants in Navrongo Ghana September 2000 June 2004
NCT00863408 Completed Estivation of Malaria Vector Mosquitoes in the Sahelian Region of Mali March 3, 2009 March 10, 2010
NCT00866619 Completed Phase 3 Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa March 27, 2009 January 31, 2014
NCT00869700 Completed Phase 4 Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected Adults June 2009 February 2010
NCT00870987 Completed Phase 1/Phase 2 Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria May 2009 July 2015
NCT00871156 Completed Phase 1 Tafenoquine/Chloroquine DDI Study March 24, 2009 August 26, 2009
NCT00873938 Completed Compliance to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana October 2005 September 2006
NCT00878007 Completed N/A Impact of Malaria Prevention on Health and Education in Kenyan Schoolchildren January 2010 April 2012
NCT00878098 Completed Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa June 1, 2009 July 12, 2019
NCT00878397 Completed N/A Impact of School-based Delivery of Long Lasting Insecticide Nets May 2009 November 2010
NCT00889616 Completed Phase 1 Phase I Study of the Safety and Immunogenicity of BSAM-2/Alhydrogel +CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium Falciparum Malaria in Adults in the US and Mali April 23, 2009 July 18, 2012
NCT00890019 Completed Phase 1 A Study of AdCh63 ME-TRAP Alone and With MVA ME-TRAP July 2007 September 2011
NCT00890760 Completed Phase 1/Phase 2 A Study to Assess the Effectiveness of a New Malaria Vaccine Candidate by Infecting Vaccinated Volunteers With Malaria Parasites March 2009 February 2011
NCT00913146 Completed Can Treatment of Malaria be Restricted to Parasitologically Confirmed Malaria? February 2008 March 2009
NCT00914225 Completed Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in Kenya September 2009 December 2011
NCT00917202 Completed Phase 2 Efficacy of Methylene Blue for Malaria Treatment in Adults of Burkina Faso: Proof of Principle Study in Semi-Immune Adults of Burkina Faso in the Frame of the A8 Project of the SFB 544
NCT00935688 Completed Phase 4 Examination of ACT Implementation in a Vivax / Falciparum Co-endemic Area May 2009 October 2010
NCT00941785 Completed Phase 2/Phase 3 Dihydroartemisinin (DHA)-Piperaquine for IPT to Prevent Malaria in Children in Burkina Faso July 2009 December 2009
NCT00944359 Completed N/A Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children December 2010 February 2012
NCT00944840 Completed Phase 3 Intermittent Preventive Treatment (IPTc) and Home Based Management of Malaria (HMM)in The Gambia September 2008 August 2009
NCT00948896 Completed Phase 3 Chemopreventive Therapy for Malaria in Ugandan Children June 2010 April 2014
NCT03510481 Completed Phase 1 Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali May 14, 2018 February 13, 2020
NCT00075049 Completed Phase 1/Phase 2 Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria December 2003 January 2006
NCT00111163 Completed N/A Intermittent Preventive Treatment With Antimalarials in Kenyan Infants March 2004 March 2008
NCT00114010 Completed Phase 1 Experimental Vaccine for Malaria April 1, 2005 December 22, 2006
NCT00115921 Completed N/A Evaluation of Home-Based Management of Fever in Urban Ugandan Children July 2005 April 2007
NCT00116766 Completed Phase 2 Field Evaluation of Plant-based Mosquito Control July 2005 September 2006
NCT00118027 Completed N/A A New Approach to Deliver Malaria Preventions to Pregnant Women at a Community Level in Uganda May 2003 June 2007
NCT00118794 Completed Phase 3 Lapdap and Coartemether for Uncomplicated Malaria September 2004 June 2005
NCT00118807 Completed Phase 3 Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children August 2003 February 2004
NCT00119132 Completed Phase 2/Phase 3 Effectiveness of Intermittent Preventive Treatment for Malaria in Children June 2005 December 2006
NCT00119145 Completed Phase 4 Kintampo Trial of Combination Therapy for Malaria June 2005 May 2006
NCT00120809 Completed Phase 3 Intermittent Preventative Treatment With Sulfadoxine-Pyrimethamine in Gambian Multigravidae July 2002 September 2004
NCT00120822 Completed Phase 3 Folic Acid Supplementation in Gambian Primigravidae July 2002 January 2004
NCT00121771 Completed Phase 1 Malaria Candidate Vaccines FP9 Circumsporozoite (CS) and MVA CS in Adult Gambian Men January 2004 July 2004
NCT00121823 Completed Phase 1/Phase 2 Malaria Infection Diagnosed by Polymerase Chain Reaction (PCR) as a Means of Evaluating Pre-erythrocytic Candidate Malaria Vaccines June 2004 December 2004
NCT00123552 Completed Phase 3 Longitudinal Antimalarial Combinations in Uganda November 2004 December 2008
NCT00125489 Completed Phase 4 CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in Malawi May 2005 December 2005
NCT00127998 Completed N/A Antimalarial Drug Resistance in Mali July 2005
NCT00130065 Completed Phase 4 The Effect of Folic Acid on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western Kenya November 2003 February 2006
NCT00131703 Completed Phase 3 Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women March 2003 March 2005
NCT00131794 Completed Phase 3 Bacillus Calmette-Guerin (BCG) Vaccine and Morbidity From Malaria January 2003 December 2003
NCT00132548 Completed Phase 3 A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children June 2004 December 2004
NCT00132561 Completed Phase 2/Phase 3 A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese Children June 2002 December 2003
NCT00137657 Completed Phase 4 Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate Resistance February 2002 November 2003
NCT00138307 Completed Correlates of Protection in Ghana March 2006
NCT00144352 Completed Phase 4 In-Vivo Response of P. Falciparum to Antimalarial Treatment in HIV-Infected and HIV-Uninfected Adults September 2002 July 2004
NCT00144716 Completed Phase 3 Evaluation of Combined Use of ITN's and Insect Repellents Against Malaria June 2003 October 2003
NCT00146692 Completed Phase 4 A Trial of Improved Financial Access to Healthcare in Ghana April 2004 February 2005
NCT00146718 Completed Phase 2/Phase 3 Anti-Malarial Drug Resistance in Cameroon August 2003 May 2005
NCT00146731 Completed Phase 3 A Trial of Antimalarial Drugs Used in Pregnancy in Tanzania January 2004 September 2007
NCT00146783 Completed Phase 2/Phase 3 Navrongo Drug Options for IPT in Pregnancy Trial June 2004 February 2007
NCT00146796 Completed Phase 4 A Randomised Trial of Rapid Diagnostic Tests in the Diagnosis of Malaria in Tanzania January 2005 November 2005
NCT00158548 Completed Phase 3 ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan June 2001 December 2004
NCT02671175 Completed Phase 3 Post-discharge Malaria Chemoprevention(PMC) Study May 20, 2016 December 12, 2018
NCT02672228 Completed N/A Feasibility of the Vapor Nanobubble Technology for Malaria Diagnostics (MalariaSense) October 2015 December 2015
NCT02687373 Completed Phase 1/Phase 2 Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya July 21, 2016 August 14, 2018
NCT02692963 Completed Phase 2 Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria Infection April 2016 February 2017
NCT02694874 Completed N/A Rosiglitazone Adjunctive Therapy for Severe Malaria in Children February 2016 December 2021
NCT02698748 Completed Phase 2/Phase 3 Evaluating the Role of Chloroquine for Malaria Elimination January 2015 June 2015
NCT02699099 Completed Phase 3 Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. May 10, 2017 October 7, 2020
NCT02704533 Completed Phase 1 Sequential Optimization of Dose and Schedule of PfSPZ Vaccine August 29, 2016 December 2018
NCT02708199 Completed Molecular Assessment of Drug Resistance Markers in Asymptomatic Malaria Cases and Malaria Antibody Kinetic January 2015 December 2015
NCT02721186 Completed N/A Effectiveness of Mass Drug Administration for Reducing Seasonal Malaria Transmission in Zanzibar April 30, 2016 September 30, 2017
NCT02741024 Completed Phase 4 Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo October 2013 December 2014
NCT02742285 Completed Phase 4 Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot May 2016 September 2016
NCT02758353 Completed N/A The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria April 2015 November 2015
NCT02783820 Completed Phase 1 Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A May 2016 December 2016
NCT02783833 Completed Phase 1/Phase 2 MMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B May 2016 January 16, 2017
NCT02788864 Completed Phase 4 Prevention of Malaria With Dihydroartemisinine + Piperaquine for Forest Rangers May 20, 2016 November 30, 2016
NCT02793336 Completed Early Life Cohort in Papua Indonesia (ELIPI Study) August 3, 2016 March 12, 2024
NCT02793622 Completed Phase 3 Prevention of Malaria in HIV-uninfected Pregnant Women and Infants September 2016 December 4, 2018
NCT02800109 Completed Child Follow-up Until 2 Years May 2016 February 2018
NCT02817919 Completed Cohort Event Monitoring in Sub Saharan Africa May 2016 March 2017
NCT02831023 Completed Phase 2 Phase 2 Efficacy Study of Primaquine and Methylene Blue July 2016 January 2017
NCT02836002 Completed Phase 1/Phase 2 Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1 June 2016 June 29, 2017
NCT02858817 Completed Phase 1 Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis November 28, 2016 November 16, 2017
NCT02859350 Completed Phase 1 Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea. November 2016 February 2018
NCT02878200 Completed N/A RHOST-cRCT, Reactive Household-based Self-administered Treatment Against Residual Malaria Transmission November 4, 2016 July 16, 2020
NCT02878265 Completed Phase 3 The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children November 2011 December 2012
NCT02885506 Completed Phase 1 A FIH Study to Investigate the Safety, Tolerability and PK of P218 August 24, 2016 December 4, 2017
NCT02894294 Completed Evaluation of Seasonal Malaria Chemoprevention in Kita July 2014 June 2015
NCT02898779 Completed Phase 1 Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1 May 1, 2017 March 1, 2018
NCT02903706 Completed Prevalence of Malaria Parasites in People Working in Illegal Gold Mining in French Guiana October 2014 June 2015
NCT02903758 Completed Frequency and Distribution of Mixed Falciparum-vivax Infections in French Guiana January 2000 December 2008
NCT02905019 Completed Phase 1/Phase 2 A Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP August 2016 December 21, 2017
NCT02909712 Completed Phase 2 Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania September 2016 February 2020
NCT02910934 Completed N/A Cost-effectiveness Evaluation of Vector Control Strategies in Mozambique January 10, 2017 December 31, 2019
NCT02914145 Completed N/A Mass Drug Administrations of DHA-PQP to Accelerate Towards Malaria Elimination in Magude District, Southern Mozambique November 2015 December 2017
NCT02925403 Completed Phase 1/Phase 2 A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, With Matrix-M1 Adjuvant August 26, 2016 February 15, 2017
NCT02927145 Completed Phase 1/Phase 2 A Challenge Study to Assess the Safety, Immunogenicity and Efficacy of a Malaria Vaccine Candidate October 17, 2016 June 27, 2019
NCT02932072 Completed Field Evaluation of a Device for Automated Malaria Microscopy (Autoscope Version 2) November 10, 2016 July 19, 2017
NCT02940756 Completed Phase 4 Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo March 15, 2017 January 2, 2018
NCT02942277 Completed Phase 1 Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali October 21, 2016 July 15, 2020
NCT02963324 Completed Phase 1 Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers November 2016 January 2017
NCT02974608 Completed Impact of Malaria on Pregnant Women in Ouelessebougou, Mali February 15, 2017 April 21, 2022
NCT02996513 Completed N/A Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) Method October 2016 June 2017
NCT03009526 Completed Phase 3 Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi January 17, 2017 October 24, 2018
NCT03035305 Completed N/A Seasonal Malaria Chemoprevention With or Without Lipid-based Nutrient Supplement in Children Aged 6-59 Months in Mali August 2016 November 2016
NCT03056391 Completed Phase 3 Effect of Paracetamol on Renal Function in Plasmodium Knowlesi Malaria October 2016 February 1, 2018
NCT03083847 Completed Phase 1 Dose Escalation PfSPZ-CVac June 5, 2017 June 26, 2019
NCT03084289 Completed Phase 1 A Study to Assess the Safety and Immunogenicity of a Candidate Malaria Vaccine Using Novel Routes of Administration March 28, 2017 July 6, 2020
NCT03128515 Completed Phase 3 Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas July 26, 2017 January 28, 2020
NCT03162614 Completed Phase 2 Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults May 24, 2017 September 24, 2018
NCT03163121 Completed Phase 1 Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers May 12, 2017 October 25, 2018
NCT03203421 Completed Phase 1/Phase 2 A Safety and Efficacy Study of ChAdOx1 LS2 and MVA LS2 July 3, 2017 December 20, 2017
NCT03208179 Completed Phase 3 Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa March 29, 2018 March 15, 2020
NCT03217851 Completed Prevalence Survey of Antimalarial Drug Resistance Markers September 18, 2017 December 24, 2021
NCT03224052 Completed Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria May 1, 2016 January 1, 2018
NCT03276962 Completed Phase 2 Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age September 28, 2017 November 14, 2022
NCT03281291 Completed An Ancillary Study Protocol to GSK's Phase IIb Malaria Vaccine Trial Entitled "Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age" November 19, 2018 April 22, 2022
NCT03304691 Completed Molecular Basis of Erythrocyte Invasion by Plasmodium Vivax Into Duffy-Negative Erythrocytes in Mali June 30, 2021 March 30, 2023
NCT03304704 Completed Community Dynamics of Malaria Transmission and Mosquito Feeding in Bancoumana, Mali January 28, 2018 July 12, 2020
NCT03334747 Completed Phase 2 Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria. November 16, 2017 November 23, 2019
NCT03341754 Completed Phase 1 Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults September 15, 2018 March 23, 2020
NCT03352843 Completed Phase 4 Single Low-dose Primaquine Efficacy and Safety. June 11, 2019 February 28, 2020
NCT03384472 Completed Malaria Genetic Surveillance in Cambodia June 1, 2016 February 1, 2017
NCT03399318 Completed Phase 2 Aggressive Antipyretics for Fever Reduction in CNS Malaria January 7, 2019 December 2, 2022
NCT03420053 Completed Phase 1 Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian Adults February 7, 2018 August 25, 2018
NCT03432039 Completed N/A Preventing Mental Health Problems After Childhood Severe Malaria January 9, 2018 July 31, 2019
NCT03436160 Completed Early Phase 1 Study Assessing Pharmacokinetics and Bioavailability of Three Novel Triazine Compounds August 10, 2018 November 3, 2018
NCT03483571 Completed Dynamics of Subclinical Malaria: Preliminary Study July 26, 2018 September 3, 2019
NCT03496454 Completed N/A Susceptibility of Gambian Adults to PfSPZ-Challenge Infection in the Controlled Human Malaria Infection Model March 29, 2018 December 5, 2018
NCT03512678 Completed Evaluation of a Digital Microscope for Malaria June 25, 2018 June 30, 2020
NCT03521973 Completed Phase 2 Safety, Tolerability and Protective Efficacy of PfSPZ Vaccine in Gabonese Children June 14, 2018 August 3, 2021
NCT03523182 Completed N/A Spirulina Supplementation and Infant Growth, Morbidity and Motor Development March 1, 2015 January 30, 2018
NCT03542149 Completed Phase 1 Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP April 23, 2018 April 19, 2019
NCT03554616 Completed N/A Efficacy of Three Novel Bi-treated Long Lasting Insecticidal Nets February 1, 2019 February 1, 2023
NCT03568344 Completed Community Access to Rectal Artesunate for Malaria June 15, 2018 August 31, 2021
NCT03576313 Completed Phase 3 Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination August 11, 2018 July 31, 2021
NCT03590340 Completed Phase 1 Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea July 30, 2018 March 12, 2019
NCT03641339 Completed N/A Defining Skin Immunity of a Bite of Key Insect Vectors in Humans September 5, 2018 May 20, 2020
NCT03641534 Completed Monitoring of Perfusion in Sepsis and Malaria June 4, 2018 September 26, 2019
NCT03671109 Completed Phase 3 Improving Maternal heAlth by Reducing Malaria in African HIV Women September 18, 2019 June 19, 2023
NCT03695770 Completed N/A Evaluation of a New Malaria Control Strategy Amongst Gold Miners Working Illegally in French Guiana (Malakit) April 16, 2018 March 30, 2020
NCT03705624 Completed N/A P. Falciparum Infection Dynamics and Transmission to Inform Elimination (INDIE-1a) August 6, 2018 February 14, 2020
NCT03707041 Completed Phase 1 Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model November 16, 2018 June 3, 2019
NCT03707353 Completed Phase 1/Phase 2 An Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP October 30, 2018 June 10, 2019
NCT03719599 Completed Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia October 1, 2019 February 4, 2021
NCT03780712 Completed Immune Dysfunction in Newborn Sepsis April 17, 2016 March 12, 2018
NCT03810014 Completed N/A Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1 March 28, 2019 October 31, 2019
NCT03824236 Completed Phase 2 A Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Booster Dose of GSK Biologicals' Candidate Malaria Vaccine Administered to Previously Vaccinated Healthy Malaria-naïve Adults February 5, 2019 September 26, 2019
NCT03874143 Completed N/A Clinical Evaluation of the Use of an mHealth Intervention on Quality of Care March 1, 2016 October 1, 2016
NCT03906474 Completed N/A VAC063C: A Study to Assess Repeat Blood-stage P. Falciparum Infection November 6, 2018 February 14, 2019
NCT03916003 Completed Phase 4 Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas August 18, 2019 July 30, 2022
NCT03917654 Completed Phase 2 Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali April 24, 2019 October 31, 2022
NCT03934450 Completed Phase 1 Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen August 17, 2018 May 1, 2019
NCT03952650 Completed Phase 1/Phase 2 Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa... May 23, 2019 February 10, 2021
NCT03963869 Completed N/A Effectiveness of Malaria Camps as Part of the Odisha State Malaria Elimination Drive August 3, 2019 March 31, 2021
NCT03970993 Completed Phase 1/Phase 2 VAC 072-An Efficacy Study of R21/MM in Different Dose Schedules June 17, 2019 August 24, 2021
NCT03989102 Completed Phase 2 Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Malaria Transmission Season in Healthy African Adult Women of Childbearing Potential in Mali July 3, 2019 March 17, 2023
NCT03996967 Completed Diagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia February 11, 2019 April 10, 2021
NCT04002687 Completed Phase 1 Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ) April 4, 2019 October 29, 2019
NCT04041973 Completed N/A Study to Assess Efficacy of Artemether-lumefantrine Prophylaxis Against Forest Malaria in Cambodia (PAL_Cambodia) March 11, 2020 March 17, 2021
NCT04069221 Completed Phase 1 Absolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study February 28, 2017 May 30, 2017
NCT04072302 Completed Phase 1 Safety and Causal Prophylactic Efficacy of KAF156 in a Controlled Human Malaria Challenge Model September 15, 2014 November 29, 2017
NCT04094727 Completed Phase 4 Malaria High-Risk Populations in Namibia October 31, 2019 June 30, 2020
NCT04102592 Completed N/A Getting Malaria "Off the Back" of Women and Children in Western Uganda October 28, 2019 March 4, 2020
NCT04105855 Completed Malaria Prevalence Around Maferinyah, Guinea July 13, 2020 October 30, 2023
NCT04157894 Completed Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Burkina Faso July 7, 2019 July 6, 2022
NCT04167566 Completed N/A Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children July 1, 2017 July 30, 2019
NCT04206332 Completed Phase 1 Trial to Evaluate CIS43LS in Healthy Adults January 7, 2020 February 28, 2022
NCT04222088 Completed TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014 May 1, 2013 December 30, 2014
NCT04230161 Completed Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda February 24, 2020 November 18, 2022
NCT04265573 Completed Feasibility, Acceptability and Costs of a Multiple First-lines Artemisinin-based Combination Therapies November 10, 2018 February 25, 2021
NCT04315272 Completed Phase 4 Gut and Azithromycin Mechanisms in Infants and Children II August 21, 2020 June 1, 2022
NCT04321252 Completed Phase 1 Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects July 22, 2020 November 10, 2020
NCT04323306 Completed Phase 1 A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533. August 12, 2020 September 27, 2022
NCT04329104 Completed Phase 2 Safety and Efficacy of CIS43LS Anti-malaria mAb in Mali February 15, 2021 July 5, 2023
NCT04370977 Completed Phase 4 In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III) March 21, 2018 December 19, 2019
NCT04428307 Completed N/A Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Kenya January 11, 2021 August 31, 2022
NCT04428385 Completed N/A Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria March 15, 2021 February 28, 2023
NCT04456634 Completed Phase 1 Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefantrine September 10, 2020 November 17, 2020
NCT04494854 Completed Perceptions, Representations and Experiences of Malaria Prophylaxis in Patients Born in Endemic Areas and Living in France. September 1, 2020 November 1, 2020
NCT04545905 Completed Antenatal Care as a Platform for Malaria Surveillance: Utilizing Community Prevalence Measures From the New Nets Project to Validate ANC Surveillance of Malaria in Burkina Faso September 22, 2020 July 31, 2022
NCT04558515 Completed Automated Microscopy Evaluation Study February 1, 2020 December 31, 2021
NCT04558528 Completed Innovation Platform October 1, 2020 July 31, 2021
NCT04566510 Completed N/A LLIN Evaluation in Uganda Project October 17, 2020 March 31, 2023
NCT04601714 Completed Baseline Cohort Malaria Morbidity Study September 7, 2020 December 31, 2021
NCT04618523 Completed Phase 4 Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo October 26, 2020 February 8, 2022
NCT04666350 Completed Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays March 9, 2021 December 20, 2021
NCT04695197 Completed Phase 3 Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso January 8, 2021 February 20, 2024
NCT04716387 Completed Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Mozambique August 18, 2020 September 30, 2022
NCT04724161 Completed Antenatal Care as a Platform for Malaria Surveillance: Utilizing Community Prevalence Measures From the New Nets Project to Validate ANC Surveillance of Malaria in Mozambique December 9, 2020 September 30, 2022
NCT04766879 Completed N/A Spatial Repellents for the Prevention of Malaria in Kenya March 2, 2021 December 9, 2023
NCT04788862 Completed N/A A Study of Blood-stage Controlled Human Plasmodium Falciparum Malaria Infection in Tanzania July 18, 2022 February 24, 2023
NCT04795648 Completed N/A Spatial Repellents for Vector Control July 8, 2021 March 2, 2024
NCT04844099 Completed Phase 3 Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia April 9, 2021 July 12, 2023
NCT04858087 Completed Malawi International Center of Excellence in Malaria Research School-based Cohort March 24, 2015 November 13, 2015
NCT04862416 Completed Phase 1 Safety and Efficacy of R0.6C Vaccine May 17, 2021 June 29, 2022
NCT04864444 Completed N/A Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities June 19, 2021 June 30, 2023
NCT04897919 Completed Phase 4 Effectiveness and Safety of Artemether + Lumefantrine and Dihydroartemisinin + Piperaquine for Treating Malaria August 1, 2015 December 1, 2018
NCT04940130 Completed Phase 2 PfSPZ Vaccine Trial in Malian Children April 1, 2022 December 10, 2022
NCT04944966 Completed Phase 2 Safety and Efficacy of Maytenus Senegalensis for the Treatment of Uncomplicated Malaria June 2, 2021 September 25, 2022
NCT04966871 Completed Phase 1 Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults September 27, 2021 June 21, 2022
NCT05019729 Completed Phase 1 Trial to Evaluate L9LS in Healthy Adults September 13, 2021 September 19, 2022
NCT05070520 Completed Phase 4 Efficacy of Antimalarial Drugs Used for the Treatment of Uncomplicated Malaria, Plasmodium Falciparum, at the Agadez, Gaya and Tessaoua Sentinel Sites September 1, 2020 October 28, 2020
NCT05072613 Completed Monitoring Pregnant Women for Antimalarial Drug Resistance November 11, 2021 May 30, 2023
NCT05084651 Completed Phase 1 Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole November 18, 2021 May 14, 2022
NCT05085301 Completed RapiGEN BIOCREDIT Malaria Ag RDTs WHO Prequalification Study December 1, 2021 May 30, 2023
NCT05095272 Completed Phase 1 Blood-Stage Plasmodium Vivax Cell Bank February 15, 2022 September 15, 2022
NCT05205941 Completed Phase 1 MMV533 Plasmodium Falciparum Volunteer Infection Study March 30, 2022 September 2, 2022
NCT05206201 Completed Phase 1 A Study Of Zy-19489 Administered Via Oral Route To Investigate The Safety, Tolerability And Pharmacokinetics In Healthy Adult Human Subjects August 25, 2021 January 21, 2022
NCT05219565 Completed N/A Evaluating ATSBs for Malaria Reduction in Kenya March 7, 2022 April 24, 2024
NCT05223933 Completed N/A Proactive Community Case Management (Pro-CCM) in Rural Madagascar December 12, 2016 December 29, 2018
NCT05236530 Completed Phase 1 Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir March 9, 2022 October 17, 2022
NCT05286359 Completed N/A Performance Evaluation of Malaria Plus Rapid Diagnostic Tests (RDTs) for the Detection of Plasmodium Infections in Patients With Symptoms Suggestive of Malaria May 24, 2022 November 17, 2022
NCT05287893 Completed Phase 1 Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria April 4, 2022 September 26, 2022
NCT05330273 Completed Phase 1 Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz April 28, 2022 November 22, 2022
NCT05444790 Completed Abbott NxTekTM Malaria RDT WHO Prequalification Study June 30, 2022 July 30, 2023
NCT05644067 Completed Phase 1 Assessment of the Malaria Vaccine Candidate SumayaVac-1 in Healthy Adults Aged 18-45 Years Living in a Malaria Endemic Country August 25, 2023 April 2, 2024
NCT05746819 Completed An MRI Ancillary Study of a Malaria Fever Investigation January 2, 2021 March 31, 2024
NCT05816330 Completed Phase 2 L9LS MAb in Malian Adults May 25, 2023 February 11, 2024
NCT05874869 Completed N/A Dihydroartemisinin-piperaquine for Seasonal Malaria Chemoprophylaxis in Tanzania July 1, 2020 June 30, 2021
NCT05930782 Completed Phase 1 Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers. July 24, 2023 January 3, 2024
NCT05958797 Completed TES of Chloroquine for Pv in the Philippines in 2016 January 4, 2016 December 29, 2016
NCT05979207 Completed Phase 1 Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum August 1, 2023 October 30, 2023
NCT06036030 Completed Phase 2 Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papua January 11, 2019 April 16, 2019
NCT06044805 Completed Phase 4 Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax December 19, 2022 March 15, 2023
NCT06179732 Completed Phase 3 Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities June 5, 2023 December 31, 2023
NCT06225700 Completed Clinical Validation of Novel Malaria Diagnostic Tools for POC Point-of-Care Testing March 1, 2023 August 1, 2023
NCT06257810 Completed Phase 4 Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West Africa June 1, 2023 October 24, 2023
NCT06300970 Completed Phase 4 Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia August 9, 2022 August 16, 2023
NCT06386367 Completed N/A Health Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar July 1, 2022 March 30, 2024
NCT00978068 Completed Phase 3 HIV Protease Inhibitors for the Prevention of Malaria in Ugandan Children September 2009 January 2013
NCT00978172 Completed Phase 4 Safety and Efficacy Study of Artesunate and Mefloquin in Children With Uncomplicated Malaria December 2007 March 2009
NCT00984256 Completed Phase 2 Weekly Dosing of Malarone ® for Prevention of Malaria September 2009 April 2010
NCT00984763 Completed Phase 1/Phase 2 A Study to Assess Safety, Immunogenicity and Parasite Growth Inhibition of an Asexual Blood Stage Vaccine for P. Falciparum Malaria January 2010 September 2010
NCT00993031 Completed Phase 3 Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women December 15, 2009 July 2013
NCT01002066 Completed Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar May 2010 February 2011
NCT01002833 Completed N/A Comparison of Three Plasmodium Falciparum Isolates in an Experimental Human Malaria Infection April 2010 November 2010
NCT01003314 Completed Phase 1/Phase 2 A Study of the Safety and Effectiveness of Two New Malaria Vaccines November 2009 September 2010
NCT01018459 Completed Phase 1 Adenovirus Type 35 Based Circumsporozoite Malaria Vaccine in Burkina Faso April 2010 December 2011
NCT01023399 Completed Phase 4 Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire November 2009 October 2013
NCT01024426 Completed Phase 4 Impact of Enhanced Health Facility Care in Uganda December 2010 July 2013
NCT01027663 Completed N/A Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum November 2009 January 2015
NCT01043744 Completed N/A Non-malarial Febrile Illness in Children in Areas of Perennial Malaria Transmission January 2010 December 2011
NCT01043796 Completed Phase 3 Evaluation of Insecticide Treated Nets and Wall Liners for the Prevention of Malaria May 2010 December 2014
NCT01048801 Completed N/A Role and Effectiveness of Rapid Diagnostic Tests in Home-based Management of Malaria March 2010 July 2012
NCT01052584 Completed N/A Ethiopia Malaria Therapeutic Efficacy Study October 2009 January 2010
NCT01054248 Completed Phase 3 Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy February 16, 2010 September 2016
NCT01062386 Completed Malaria Survey in Mbarara District, Uganda 2010 January 2010 July 2010
NCT01065116 Completed Phase 3 Artemether-Lumefantrine (AL) Unit Dose Pre-packs Versus Blister Packs March 2010 November 2010
NCT01080989 Completed N/A The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands March 2009 December 2011
NCT01082341 Completed Phase 1/Phase 2 Immunization of Human Volunteers With P. Vivax Irradiated Sporozoites June 2012 September 2017
NCT01084213 Completed Phase 4 Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy June 2010 October 2012
NCT01086917 Completed Phase 1 Experimental Human Malaria Infection by PfSPZ August 2010 July 2011
NCT01095055 Completed Phase 1 A Study of AdCh63 AMA1 Alone and With MVA AMA1 March 2010 October 2010
NCT01115478 Completed N/A Malaria in Pregnancy: Nutrition and Immunologic Effects July 2010 June 2014
NCT01119612 Completed N/A Prenatal Iron Supplements: Safety and Efficacy in Tanzania September 2010 May 2013
NCT01133314 Completed Artemether-Lumefantrine Effectiveness in Guinea-Bissau 2 May 2010 July 2016
NCT01142765 Completed Phase 1/Phase 2 Study to Assess Efficacy of New Malaria Vaccine Candidates AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & MVA ME-TRAP June 2010 March 2011
NCT01148459 Completed Phase 3 Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and Children July 30, 2010 May 24, 2013
NCT01150344 Completed Phase 4 Evaluation of the Riamet® Versus Malarone® in the Treatment of Uncomplicated Malaria July 2010 November 2015
NCT01152931 Completed Phase 3 Antioxidant Micronutrients in Malaria August 2010 December 2010
NCT01154803 Completed N/A Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection February 2012 February 2013
NCT01156389 Completed Phase 1 Pyronaridine Artesunate-Ritonavir Drug-drug Interaction Study July 2010 September 2010
NCT01157689 Completed Artemether-Lumefantrine Effectiveness in Guinea-Bissau March 2010 June 2016
NCT01157897 Completed Phase 1/Phase 2 Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults July 2010 January 2012
NCT01160809 Completed Phase 4 Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia September 2008 January 2009
NCT01165372 Completed Phase 2 Study of Malaria Treatment at Phuoc Long Hospital, Binh Phuoc Province, Vietnam August 2010 May 2011
NCT01166815 Completed Phase 2/Phase 3 Zinc Supplementation to Reduce Diarrhea Rates in Adults in Western Kenya. July 2007 January 2008
NCT01190202 Completed N/A Epidemiology Study of Malaria Transmission Intensity in Africa March 14, 2011 December 20, 2013
NCT01194557 Completed N/A Introducing Rapid Diagnostic Tests Into the Private Health Sector September 2010 July 2012
NCT01196520 Completed Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM) May 25, 2010 May 21, 2020
NCT01205178 Completed Phase 1 G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine) July 2, 2009 April 1, 2013
NCT01210040 Completed N/A Long-term Iron Supplements and Malaria Risk in Early Pregnancy: a Randomized Controlled Trial April 2011 January 2014
NCT01214876 Completed Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires August 2010 March 2011
NCT01228344 Completed Surveillance of Effectiveness/Safety of Artemether-lumefantrine in Patients With Malaria May 1, 2010 September 30, 2015
NCT01231503 Completed Phase 2 Safety and Immunogenicity of GSK Biologicals' Malaria Vaccine 257049 When Administered on 7 Schedules to African Infants January 13, 2011 December 23, 2014
NCT01231880 Completed Phase 3 School Based Malaria Control in Ugandan Schoolchildren February 2011 September 2012
NCT01232530 Completed Pharmacovigilance for ACTs in Africa June 2010 December 2013
NCT01240603 Completed Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia October 24, 2010 September 11, 2013
NCT01256658 Completed Phase 4 A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®) November 2010 July 2012
NCT01265407 Completed Malaria Surveillance in Rakai, Uganda December 22, 2010 July 23, 2013
NCT01280162 Completed N/A Malaria Active Epidemiology and Treatment Study September 2010 December 2012
NCT01292707 Completed N/A A Cluster-randomised Trial of Interventions to Improve Antimalarial Prescribing With Malaria Tests February 2011 April 2012
NCT01308112 Completed Phase 4 Prenatal Iron and Malaria Study October 2011 May 2013
NCT01319448 Completed Phase 1/Phase 2 Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease September 2011 April 2013
NCT01322581 Completed A Longitudinal Systems Biological Analysis of Naturally Acquired Malaria Immunity in Mali May 1, 2011 March 29, 2022
NCT01323972 Completed Phase 3 Consistency of Immunogenicity and Non Inferiority of GSK Biologicals' Candidate Malaria Vaccine Lots in Children May 16, 2011 May 4, 2012
NCT01328990 Completed Phase 1/Phase 2 Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc) April 2011 July 2011
NCT01341704 Completed Phase 2 Proof-of-Concept Study of MSP3-LSP Vaccine to Protect Against Malaria in Africa May 2011 March 2013
NCT01345240 Completed Phase 3 Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) November 17, 2011 February 9, 2017
NCT01350752 Completed N/A Research on the Economics of Artemisinin Combination Therapy (ACTs) for the Treatment of Malaria May 2011 January 2015
NCT01351948 Completed Phase 1 Safety and Immunogenicity of Malaria Vaccines AdCh63 AMA1, MVA AMA1 and AMA1-C1/Alhydrogel®+/- CPG 7909 June 2011 March 2013
NCT01360112 Completed Preventing the Spread of Malaria in Mali May 20, 2011 November 16, 2017
NCT01364883 Completed Phase 1 Safety and Immunogenicity of Novel Vaccination Schedules With Malaria Vaccines AdCh63 ME-TRAP and MVA ME-TRAP July 2011 July 2013
NCT01366534 Completed Phase 2 Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults August 10, 2011 July 3, 2012
NCT01373879 Completed Phase 1 AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Adults and Children in a Malaria Endemic Area June 2010 December 2011
NCT01374581 Completed Phase 3 Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated Malaria May 2012 June 2014
NCT01378286 Completed Phase 3 Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria January 2012 June 2013
NCT01379430 Completed Phase 1 Safety and Immunogenicity of AdCh63 ME-TRAP and MVA ME-TRAP Vaccines in Malaria Endemic Areas June 2010 May 2011
NCT01383109 Completed Phase 1 Human Mass Balance Study of Pyronaridine June 2011 December 2011
NCT01389557 Completed Phase 4 Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra February 2011 December 2011
NCT01392014 Completed Phase 4 Dihydroartemisinin-piperaquine and Primaquine for Uncomplicated Plasmodium Falciparum Cases December 2008 October 2010
NCT01397227 Completed Phase 1/Phase 2 A Study to Assess the Immunogenicity, Tolerability and Safety of a Malaria Vaccine and Also Its Protective Efficacy in a Malaria Challenge Model June 2011 May 2012
NCT01397851 Completed N/A Stimulating Private Sector Malaria Control December 2010 December 2013
NCT01403350 Completed Phase 4 Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan February 2012 August 2012
NCT01422954 Completed N/A Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis January 2012 April 2013
NCT01425073 Completed N/A Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in Kenya February 2012 October 2013
NCT01434381 Completed Phase 1 Initial Study of Malaria Vaccine Pfs25-EPA/Alhydrogel(Registered Trademark) August 2011 August 2013
NCT01441167 Completed Phase 1 Experimental PfSPZ Vaccine in Adults Without Malaria September 14, 2011 June 5, 2013
NCT01443130 Completed Phase 3 Chloroquine for Malaria in Pregnancy February 2012 January 2015
NCT01449045 Completed Phase 3 Trial of Malaria Seasonal IPTc Combined With Community Case Management July 2011 February 2012
NCT01450280 Completed Phase 1 Safety and Immunogenicity of New Malaria Vaccine Candidate ChAd63 CS Administered Alone and With MVA CS December 2011 October 2012
NCT01450293 Completed Phase 1 AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Children in a Malaria Endemic Area October 2011 March 2013
NCT01454752 Completed N/A Intermittent Parasite Clearance (IPC) in Schools: Impact on Malaria, Anaemia and Cognition November 2011 February 2012
NCT01456858 Completed Phase 3 Insecticide Treated Polyethylene Sheeting for Prevention of Malaria in Emergencies December 2003 July 2004
NCT01464138 Completed Phase 2 Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children September 2010 September 2011
NCT01465048 Completed N/A Optimisation of Controlled Human Malaria Infection Using Sporozoites Administered by Needle and Syringe October 2011 February 2013
NCT01500980 Completed Phase 1 Malaria Challenge in Healthy Volunteers December 2011 November 2012
NCT01517230 Completed N/A Can Mass Media Campaigns Reduce Child Mortality March 2012 April 2015
NCT01523002 Completed Phase 1 Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate January 2012 October 2012
NCT01524341 Completed Phase 2 Efficacy, Safety, Tolerability and Pharmacokinetics of KAE609 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection January 2012 June 2012
NCT01540474 Completed Phase 1 Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive Adults February 2012 December 2012
NCT01540903 Completed Phase 1 Controlled Human Malaria Infection by Intradermal Injection of Plasmodium Falciparum Sporozoites in Tanzanian Adults February 2012 August 2013
NCT01545115 Completed Study of the Environmental Factors Modulating Children Immune Response in Northern Senegal October 2008 February 2010
NCT01546389 Completed Phase 1 Sanaria™ PfSPZ Challenge Vaccine April 2012 April 2013
NCT01575613 Completed N/A Reducing the Burden of Malaria by Targeting Hotspots of Malaria Transmission April 2012 November 2012
NCT01585077 Completed Phase 1/Phase 2 Exposure of Naive and Pre-immune Subjects to P. Vivax Challenge October 2012 November 2013
NCT01603251 Completed Phase 1/Phase 2 Trial of Artemether-Lumefantrine Alone and in Combination With Ivermectin to Reduce Post-Treatment Malaria Transmission January 2013 April 2013
NCT01614964 Completed Phase 2 Studies of a Candidate Aminoquinoline Antimalarial (AQ-13) August 2013 February 2017
NCT01624961 Completed Phase 1 Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults June 2012 February 2013
NCT01627951 Completed N/A Comparison of Three Plasmodium Falciparum Isolates in a Controlled Human Malaria Infection August 2012 November 2012
NCT01635647 Completed Phase 1/Phase 2 A Phase 1/2b Study of an Investigational Malaria Vaccination Strategy in 5-17 Month Old Infants and Children in Burkina Faso November 2012 September 2014
NCT01641289 Completed N/A Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria July 10, 2012 September 21, 2014
NCT01651416 Completed Phase 4 Seasonal Malaria Chemoprevention Versus Home Management of Malaria in Children Under 5 Years in Ghana July 2012 July 2013
NCT01652365 Completed N/A Feasibility and Impact of Malaria Rapid Diagnostic Tests in the African Retail Sector March 2011 June 2012
NCT01658696 Completed Phase 2 Efficacy of Candidate Malaria Vaccines in Senegalese Adults August 2012 February 2013
NCT01658774 Completed N/A Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children January 2013 January 2015
NCT01663831 Completed N/A Repellents as Added Control Measure to Long Lasting Insecticidal Nets May 2012 December 2013
NCT01666925 Completed Phase 2 Efficacy of Malaria Vaccines in Kenyan Adults March 2012 August 2012
NCT01669512 Completed Phase 1 Adjuvanting Viral Vectored Malaria Vaccines With Matrix M August 2012 December 2014
NCT01669941 Completed Phase 4 Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya August 2012 December 2015
NCT01697787 Completed Phase 4 Amodiaquine-Artesunate & Artemether-Lumefantrine Efficacy in Burkina Faso October 2012 September 2014
NCT01703884 Completed Phase 4 ANC & Malaria Diagnostic in Pregnancy August 2012 December 2014
NCT01704508 Completed Phase 4 Improving Anti-malarial Treatment Options in Guinea-Bissau - Part A November 2012 July 2016
NCT01713608 Completed Phase 1 A Dose-escalation Study to Investigate Safety and Toleration of OZ439 November 2012 February 2013
NCT01713621 Completed Phase 2 OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation March 2013 April 2015
NCT01717885 Completed Antimalarial Pharmacology in Children and Pregnant Women in Uganda August 2012 September 2016
NCT01722734 Completed N/A Preserving ACTs - Text Reminders to Increase Adherence to ACT Treatment June 2011 January 2013
NCT01728701 Completed Phase 1 Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis September 2012 February 2014
NCT01743417 Completed N/A Computerized Cognitive Rehabilitation in Children After Severe Malaria April 2011 August 23, 2016
NCT01743820 Completed Phase 2 Phase2a Primaquine Dose Escalation Study September 2013 December 2014
NCT01753323 Completed Phase 2 Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection March 2013 August 2014
NCT01754701 Completed N/A Acute vs. Delayed Iron: Effect on Red Cell Iron Incorporation in Severe Malaria June 2013 May 2015
NCT01755559 Completed Phase 4 Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi Niger June 2013 November 2014
NCT01766830 Completed N/A Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) January 2013 July 2016
NCT01771848 Completed Phase 1 Optimization of Controlled Human Malarial Infection by Injection of P. Falciparum Sporozoites in Non-Immune Adults December 2012 July 2013
NCT01782001 Completed Phase 3 Evaluation of Vitamin A and Zinc Supplementation on Malarial Morbidity March 2009 November 2009
NCT01809873 Completed N/A Sustainable Financial Incentives To Improve Prescription Practices For Malaria September 2012 March 2014
NCT01814423 Completed Phase 4 Pharmacokinetic Study of Multi-dose Chloroquine April 2013 March 2014
NCT01816113 Completed Phase 1 Phase Ia Study of ChAd63/MVA PvDBP April 2013 July 2014
NCT01836458 Completed Phase 2 A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum Monoinfection January 2014 March 2015
NCT01836731 Completed N/A Impact Evaluation of Community-Based Health Programs in Rwanda April 2013 June 30, 2017
NCT01838902 Completed Phase 3 Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers August 2013 October 2015
NCT01845701 Completed Phase 3 Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon March 2010 April 2015
NCT01853475 Completed Phase 1 Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted State April 2013 July 2013
NCT01857869 Completed Phase 2 Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults May 20, 2013 December 16, 2014
NCT01858831 Completed Phase 1 Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone Suspension April 2012 May 2012
NCT01867463 Completed Phase 1 Testing Pfs25-EPA/Alhydrogel as a Potential Malaria Transmission Blocking Vaccine March 27, 2013 December 19, 2016
NCT01868438 Completed Phase 1 Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers May 2013 January 2014
NCT01878357 Completed Phase 4 Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine June 2013 November 2013
NCT01902797 Completed N/A Malaria Survey in the Tak Province Refugee Camps July 2013 December 2013
NCT01907672 Completed Phase 4 The Role of Rapid Diagnostic Tests for Malaria for Targeting of ACTs at Community Level August 2011 April 2013
NCT01916954 Completed Phase 3 Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Malaria in Pregnancy July 2013
NCT01921413 Completed Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT) July 2013 February 2014
NCT01935882 Completed Phase 2/Phase 3 Low Dose Primaquine for Clearance of Gametocytes September 2013 July 2015
NCT01936766 Completed Optimal Fluid Management in Adult Severe Malaria May 2013 December 2017
NCT01939886 Completed Phase 3 Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) April 2013 November 2013
NCT01949909 Completed Phase 1 Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A : Phase Ia/Ib March 2014 July 2015
NCT01954264 Completed N/A Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa October 19, 2013 November 25, 2013
NCT01955382 Completed Phase 2 Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria September 2013 July 2015
NCT01958619 Completed Phase 1 Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers October 2013 January 2014
NCT01958905 Completed N/A Efficacy and Bio-availability of Artemether-Lumefantrine in Severely Malnourished Children November 2013 May 2015
NCT01967472 Completed N/A Adherence to Antimalarial Drugs in Sierra Leone September 16, 2013 January 2014
NCT01972321 Completed N/A ICCM of Common Childhood Diseases: Mozambique and Uganda April 2013 December 2015
NCT01976416 Completed Phase 3 Novel Use Of Hydroxyurea in an African Region With Malaria September 2014 November 2017
NCT01976780 Completed Phase 4 In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy June 2013 December 2014
NCT01988636 Completed Phase 1 Study of Safety and Effectiveness of Intravenous Immunization With PfSPZ Vaccine in Healthy African Adults October 29, 2013 August 20, 2015
NCT01994525 Completed Phase 1 Immunization Via Mosquito Bite With Radiation-attenuated Sporozoites January 24, 2014 February 2017
NCT02009215 Completed Phase 4 School-Based Treatment With ACT to Reduce Transmission February 2014 April 2015
NCT02013687 Completed Phase 1 Safety and Immunogenicity of Plant-Derived Pfs25 VLP-FhCMB Malaria Transmission Blocking Vaccine in Healthy Adults October 2013 January 2015
NCT02015091 Completed Phase 1 Study of Controlled Human Malaria Infections to Evaluate Protection After Intravenous or Intramuscular Administration of PfSPZ Vaccine in Malaria-Naive Adults December 12, 2013 September 8, 2016
NCT02043652 Completed N/A Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, Brazil February 2014 December 2014
NCT02052323 Completed Phase 4 Harmonized AS/MQ Efficacy Study - Thailand October 2013 October 2015
NCT02072629 Completed N/A HCU: Can VHVs Trained in ICCM Improve Care for Children November 2009 December 2012
NCT02080026 Completed N/A Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis June 2014 July 2015
NCT02083068 Completed Phase 2 Evaluation of the Protective Efficacy of a Vaccine Derived From the Synthetic CS Protein of Plasmodium Vivax August 2014 July 2017
NCT02083406 Completed Phase 1 Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP) July 2014 July 2014
NCT02083887 Completed Phase 1 A Phase I Study to Assess the Safety and Immunogenicity of ChAd63 ME-TRAP - MVA ME-TRAP Heterologous Prime-boost Vaccination Co-administered With EPI Vaccines in Gambian Infants February 2014 November 2015
NCT02094508 Completed Impact of TMP-SMX Prophylaxis on Malaria Infection and Immunity in Children in Uganda March 7, 2014 December 14, 2016
NCT02098590 Completed N/A Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection October 2014 November 2015
NCT02115516 Completed Phase 1 Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chemoprophylaxis April 2014 April 2016
NCT02118402 Completed N/A Iron and Prebiotics Fortification in Kenyan Infants July 2014 December 2015
NCT02118428 Completed N/A Clinical and Biological Efficacy of Mirasol-treated Fresh Whole Blood for the Prevention of Transfusion-transmitted Malaria March 2014 December 2014
NCT02119312 Completed Malaria Clinical Trials Center General Screening June 2010 September 1, 2020
NCT02132299 Completed Phase 1 Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults April 2014 August 2015
NCT02149550 Completed N/A Controlled Human Malaria Infection After Bites From Mosquitoes Infected With Two Novel P. Falciparum Strains August 2014 November 2014
NCT02151578 Completed Phase 4 Home Management of Malaria and Pneumonia January 2009 September 2012
NCT02163447 Completed Phase 3 Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants June 23, 2014 May 14, 2018
NCT02168569 Completed Phase 4 In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children June 2011 January 2013
NCT02174900 Completed Phase 2/Phase 3 Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM) October 2014 December 2015
NCT02174978 Completed Phase 1 Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults August 2014 October 2015
NCT02181088 Completed Phase 1 A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5 August 2014 October 2015
NCT02199977 Completed N/A Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector June 2014 July 2015
NCT02206451 Completed Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Mali July 16, 2014 July 16, 2014
NCT02207816 Completed Phase 3 An Extension to Study MALARIA-055 PRI (NCT00866619) to Evaluate the Long-term Efficacy, Safety and Immunogenicity of GSK Biologicals' Candidate Malaria Vaccine in Infants and Children in Africa September 18, 2014 January 31, 2017
NCT02211729 Completed Phase 3 A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children May 2014 December 31, 2017
NCT02213211 Completed N/A School-based Programme of Malaria Diagnosis and Treatment in Southern Malawi April 2014 March 2015
NCT02215707 Completed Phase 1 A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses June 2014 June 2015
NCT02230579 Completed Phase 1 Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers May 2014 February 2015
NCT02237586 Completed Phase 1 Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge July 2014 February 2015
NCT02242799 Completed Phase 1 Dolutegravir Interactions With Artemisinin-based Combination Therapies June 2015 September 2016
NCT02259426 Completed Phase 3 Dihydroartemisinin-piperaquine With Low Dose Primaquine to Reduce Malaria Transmission October 2014 December 2015
NCT02282293 Completed Phase 3 Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2) December 9, 2014 May 26, 2016
NCT02288637 Completed N/A Evaluation of a Novel Long Lasting Insecticidal Net and Indoor Residual Spray Product September 2014 April 2018
NCT02294188 Completed N/A Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Indonesia May 2015 April 15, 2018
NCT02313376 Completed Phase 1 Safety, Attenuation and Immunogenicity of GAP3KO Administered Via A Stephensi Mosquitoes December 2014 August 2015
NCT02315690 Completed Phase 3 Evaluation of Reactive Focal Mass Drug Administration for Malaria Elimination in Swaziland September 2015 July 2017
NCT02329301 Completed N/A Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern Zambia September 2014 August 2020
NCT02334462 Completed Phase 1 Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and Mali January 7, 2015 October 22, 2018
NCT02374450 Completed A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine October 5, 2015 July 29, 2022
NCT02374580 Completed Partnership and Dignity: a Mixed-methods Survey on Supporting and Retaining Uganda's Village Health Teams February 2015 May 2015
NCT02387580 Completed Phase 1 Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets April 2015 June 2015
NCT02389348 Completed Phase 1/Phase 2 A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265 February 2015 June 2015
NCT02389374 Completed Phase 4 A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh August 2014 March 2015
NCT02392832 Completed N/A Evaluation of Long-Lasting Microbial Larvicides in Reducing Malaria Transmission and Clinical Malaria Incidence April 2015 September 2019
NCT02394197 Completed Phase 4 Effectiveness of Malaria Treatment in Mexico February 2008 September 2010
NCT02411994 Completed Phase 3 Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria October 2015 August 2017
NCT02418962 Completed Phase 1 Safety and Immunogenicity of Direct Venous Inoculation of a Radiation-attenuated PfSPZ Vaccine in Equatoguinean Adults March 2015 February 2016
NCT02431637 Completed Phase 1 Experimental Falciparum Transmission to Anopheles April 2015 September 2016
NCT02431650 Completed Phase 1/Phase 2 Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent April 2015 September 2016
NCT02453581 Completed Phase 1 Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers September 2012 March 2013
NCT02458066 Completed N/A Trial to Compare Effectiveness of 2 Insecticides in Preventing Malaria February 2014 October 2014
NCT02458092 Completed Phase 1 Evaluate the Safety and Efficacy of Plasmodium Falciparum Malaria Protein 010 (FMP010) Administered With Adjuvant AS01B April 2008 June 2009
NCT02461628 Completed N/A Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2) July 2015 July 12, 2017
NCT02473796 Completed N/A Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT January 2004 April 2010
NCT02488902 Completed Phase 2 A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum August 1998 March 2003
NCT02491606 Completed Phase 2 Evaluation of Weekly Tafenoquine May 1997 September 1998
NCT02492178 Completed Phase 2 Bio-availability of Rectal Artesunate in Children With Severe Falciparum Malaria July 2015 October 2015
NCT02504918 Completed Markers of T Cell Suppression: Associations With Malaria Infection and Antimalarial Treatment in Malian Children July 21, 2015 June 12, 2018
NCT02509481 Completed Phase 2/Phase 3 Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study June 2015 December 2015
NCT02511054 Completed Phase 1 Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B... July 21, 2015 June 1, 2017
NCT02511353 Completed Phase 2 Efficacy and Safety of High-dose Ivermectin for Reducing Malaria Transmission: A Dose Finding Study July 2015 July 2016
NCT02517879 Completed N/A Community Point Distribution of Insecticide Treated Bed Nets November 2013 May 2014
NCT02527005 Completed Phase 1 A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients September 2015 August 2016
NCT02528279 Completed N/A Relapses in Plasmodium Ovale and Efficacy of Artemether-lumefantrine for Mixed Species and Non-falciparum Malaria October 2014 October 2016
NCT02532049 Completed Phase 1 A Clinical Trial to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 Pfs25-IMX313 and MVA Pfs25-IMX313 October 12, 2015 May 25, 2017
NCT02535767 Completed Phase 1/Phase 2 Determining a Tolerable Dose of Primaquine in G6PD-deficient Persons Without Malaria in Mali August 2015 January 2016
NCT02536222 Completed Phase 4 Accelerating the Reduction of Malaria Transmission in Kanel, Ranérou and Linguère Districts September 2015 July 2016
NCT02544048 Completed Markers of T Cell Suppression: Antimalarial Treatment and Vaccine Responses in Healthy Malian Adults September 4, 2015 August 11, 2017
NCT02554799 Completed Phase 1 A Study to Evaluate the Pharmacokinetics of Oral Formulations of MMV390048 Administered Fasted to Healthy Volunteers September 17, 2015 October 28, 2015
NCT02556242 Completed Phase 4 Targeted Indoor Residual Spraying Against Malaria October 2015 July 2017
NCT02561624 Completed N/A Hati Salama (Secure Voucher) July 2015 January 2016
NCT02563704 Completed Phase 3 A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon September 2013 March 2014
NCT02572388 Completed Phase 1 A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, Administered With and Without Matrix-M1 October 15, 2015 August 29, 2017
NCT02590627 Completed Phase 4 In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure May 2014 December 2015
NCT02592408 Completed Phase 4 A Study to Assess Current Standard Malaria Treatment Guidelines in the Republic of the Sudan November 2015 May 2016
NCT02600767 Completed N/A Artemether-lumefantrine for Treatment of P. Falciparum Malaria in Brazil December 2015 December 2016
NCT02600975 Completed Phase 1 A Study to Assess the Safety and Immunogenicity of a Malaria Vaccine Candidate, R21, Administered With AS01B December 8, 2015 January 19, 2017
NCT02601716 Completed Phase 2 PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults January 2016 November 2017
NCT02605720 Completed Phase 3 Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns September 2015 February 2016
NCT02610400 Completed Phase 3 Evaluation of Reactive Focal Mass Drug Administration (rfMDA) +/- Reactive Focal Vector Control (RAVC) in Namibia February 2016 December 2017
NCT02613520 Completed Phase 1 Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants December 2015 March 2017
NCT02627456 Completed Phase 1 Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites in Healthy African Adults in Mali December 9, 2015 July 3, 2018
NCT02645513 Completed N/A Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi January 2015 February 2016
NCT02654912 Completed Phase 4 Community-led Responses for Elimination: Controlled Trial of Reactive Case Detection Versus Reactive Drug Administration February 2016 July 2020
NCT02658253 Completed Phase 1 Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults January 2016 February 21, 2019
NCT02659566 Completed Impact of Antimalarial Treatment on Measures of T Cell Suppression/Regulation in Healthy Adults From Doneguebougou, Mali January 15, 2016 June 12, 2018
NCT02661373 Completed Phase 1 First-in-Human Study of an Oral Plasmodium Falciparum Plasma Membrane Protein Inhibitor March 1, 2016 March 9, 2018
NCT03897673 Enrolling by invitation N/A Optimizing Benefits While Reducing Risks of Iron in Malaria-endemic Areas September 1, 2019 July 1, 2024
NCT06461026 Not yet recruiting Phase 1 L9LS MAb in Malian Infants August 2024 August 2025
NCT05441410 Not yet recruiting Phase 1/Phase 2 Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults October 1, 2024 October 30, 2025
NCT06122142 Not yet recruiting N/A Spatial Repellents for Malaria Control May 2024 May 2025
NCT05690841 Not yet recruiting Phase 3 FocaL Mass Drug Administration for Vivax Malaria Elimination June 1, 2024 May 1, 2027
NCT05796193 Not yet recruiting N/A Net Transition Initiative: Efficacy of Two Next-generation Nets for Control of Malaria in Cote d'Ivoire July 2023 December 2024
NCT05905432 Not yet recruiting Phase 1 Pan-Malaria Transmission-Blocking Vaccine AnAPN1 July 25, 2023 December 31, 2023
NCT06173206 Not yet recruiting Phase 3 Parasite Clearance and Protection From Infection (PCPI) in Cameroon May 15, 2024 March 15, 2025
NCT06182176 Not yet recruiting N/A Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control May 27, 2024 January 12, 2026
NCT06232954 Not yet recruiting N/A Evaluation of the Protective Efficacy of a Spatial Repellent to Reduce Malaria Prevalence in Uganda February 2024 September 2025
NCT05934318 Not yet recruiting N/A L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE) September 30, 2023 December 30, 2026
NCT04672577 Not yet recruiting Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria January 30, 2021 December 31, 2025
NCT06166498 Not yet recruiting Phase 3 Parasite Clearance and Protection From Infection (PCPI) in Zambia February 15, 2024 February 15, 2025
NCT05426434 Recruiting Phase 3 Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy August 31, 2022 December 2025
NCT05946642 Recruiting Phase 3 Innovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Burkina Faso July 15, 2023 December 31, 2024
NCT05788094 Recruiting Phase 4 ACT vs CQ With Tafenoquine for P. Vivax Mono-infection June 26, 2023 August 31, 2025
NCT04228315 Recruiting N/A Biomarkers of P. Vivax Relapse November 19, 2019 December 31, 2024
NCT05856357 Recruiting Perennial Malaria Chemoprevention (PMC) in Côte d'Ivoire August 11, 2023 July 2025
NCT04839900 Recruiting N/A Proactive Community Case Management for Malaria in Zambia April 15, 2021 December 30, 2023
NCT01168271 Recruiting Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali August 30, 2010
NCT03503058 Recruiting Phase 2 Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria May 7, 2022 December 2024
NCT00001645 Recruiting Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection October 10, 1998
NCT05891236 Recruiting Phase 1 Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults August 14, 2023 June 2025
NCT05058885 Recruiting Plasmodium Vivax Among Duffy Negative Population in Cameroon. May 2, 2022 June 30, 2024
NCT05950191 Recruiting N/A LLIN Evaluation in Uganda Project (LLINEUP3) November 27, 2023 December 31, 2025
NCT04050566 Recruiting Malaria Birth Cohort (MBC) in Agogo, Ghana April 8, 2019 April 2025
NCT05978037 Recruiting Phase 1/Phase 2 A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines August 18, 2023 March 10, 2025
NCT06294912 Recruiting Phase 1 A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003) April 18, 2024 March 24, 2025
NCT05878366 Recruiting N/A Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC) July 13, 2023 October 2024
NCT06318078 Recruiting N/A Buikwe Electronic Community Health Information System Impact Study December 1, 2023 July 2024
NCT02251704 Recruiting Phase 4 Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa October 22, 2014 August 5, 2024
NCT05889052 Recruiting Perennial Malaria Chemoprevention (PMC) in Cameroon July 19, 2023 July 2025
NCT04478370 Recruiting N/A Characterizing Humoral Immune Response to Mosquito Bites January 21, 2021 December 31, 2024
NCT03937817 Recruiting Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants September 25, 2019 March 31, 2029
NCT05400655 Recruiting Phase 2 Anti-malaria MAb in Kenyan Children September 14, 2022 June 30, 2024
NCT06040346 Recruiting Phase 2 Open-Label Study to Assess Meplazumab in Adult Patients Diagnosed With Plasmodium Falciparum April 26, 2024 December 9, 2024
NCT05285735 Recruiting Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants June 8, 2022 July 1, 2029
NCT06069544 Recruiting Phase 1/Phase 2 A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria November 13, 2023 December 2025
NCT05535465 Recruiting N/A Malaria Control : Improving Access to Prevention, Diagnostic and Care for Vulnerable Rural Communities December 1, 2021 September 1, 2024
NCT04529434 Recruiting N/A Star Homes Project 2 January 4, 2022 December 31, 2025
NCT05149157 Recruiting Trajectories and Mechanisms of Recovery From Malaria: An Observational Study August 2, 2022 January 5, 2026
NCT02471378 Recruiting Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates July 28, 2015 June 30, 2024
NCT05913973 Recruiting Phase 1 Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults August 4, 2023 May 15, 2025
NCT06278181 Recruiting Diabetes, Metabolic Syndrome and Risk of Malaria in Cameroon September 21, 2023 January 30, 2025
NCT02639299 Recruiting Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge December 8, 2016 September 30, 2030
NCT03754322 Recruiting N/A LAMP Detection of Malaria in PREGnancy (LAMPREG) Trial June 18, 2021 December 31, 2023
NCT05085340 Recruiting MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention February 14, 2022 October 2025
NCT06141057 Recruiting Phase 1 A Study to Compare Two Dosing Regimens for a New Malaria Vaccine June 6, 2023 August 2025
NCT05306067 Recruiting Plasmodium Falciparum Genomic Intelligence in Mozambique October 12, 2021 February 2024
NCT05979896 Recruiting Phase 4 Chemoprevention Efficacy Study Nigeria July 28, 2023 May 15, 2024
NCT03855995 Recruiting A Study to Evaluate the Safety, Effectiveness and Impact of the GlaxoSmithKline Biologicals' Malaria Vaccine- RTS, S/AS01E in Young Children in Sub-Saharan Africa March 21, 2019 February 26, 2025
NCT05605925 Recruiting Phase 4 Ivermectin-artemisinin Combination Therapy for Eradication of Malaria August 4, 2022 December 31, 2022
NCT00442403 Suspended Phase 3 Safety and Efficacy of Chloroquine Associated With Dehydroepiandrosterone Sulphate to Treat Uncomplicated Falciparum Malaria April 2002 September 2002
NCT05218304 Suspended N/A Baromètre Santé Adulte 2021-2022 July 26, 2021 May 30, 2022
NCT05652504 Suspended Phase 1 Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1) June 23, 2024 November 30, 2024
NCT00465257 Suspended Phase 4 Efficacy of Artesunate + Amodiaquine Four Years After Its Introduction in Zanzibar May 2007
NCT00126971 Suspended Phase 1 Chlorproguanil-Dapsone in Pregnant Women July 2005
NCT04368910 Terminated Phase 3 Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria September 6, 2007 November 15, 2010
NCT00964691 Terminated Phase 4 A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands August 2009 August 2010
NCT03490162 Terminated Phase 1 Safety and Pharmacokinetics Study of DM1157 to Treat Malaria July 31, 2018 September 6, 2019
NCT01445938 Terminated Phase 2 Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria October 2011 January 2012
NCT01728961 Terminated Phase 4 Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy February 2012 March 2014
NCT00453856 Terminated Phase 4 Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children March 2007
NCT00259142 Terminated N/A Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies November 2005 November 2005
NCT01862783 Terminated Collection of Biological Material From Pregnant Women in a Malarial Region February 10, 2013 March 15, 2016
NCT02153996 Terminated Longitudinal Analysis of Plasmodium Falciparum-Specific Immunity in Travelers and Immigrants From Malaria Endemic Areas to the United States May 15, 2014 March 15, 2016
NCT00739206 Terminated Phase 2 Study of SAR97276A in the Treatment of Uncomplicated and Severe Malaria in Adults and Children. August 2008 June 2009
NCT01615822 Terminated Phase 1 Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers August 2012 April 2013
NCT01624337 Terminated N/A Malaria Prevention Cambodia May 2012 June 2015
NCT02533336 Terminated Phase 3 The Effectiveness of Non-Pyrethroid Insecticide-Treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania November 9, 2015 March 31, 2017
NCT02573857 Terminated Phase 1/Phase 2 A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection October 2015 May 2016
NCT05604521 Terminated Phase 1 A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI December 6, 2022 September 5, 2023
NCT00361114 Terminated Phase 3 IPT and Efficacy of Sulphadoxine/Pyrimethamine and Chlorproguanil/Dapsone in 6-59 Month Old Children With Malaria. July 2006 October 2007
NCT00386750 Terminated Phase 4 Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function June 2005 November 2005
NCT01024686 Terminated Phase 1/Phase 2 Phase 1/2a Trial of Pf GAP p52-/p36- Sporozoite Malaria Vaccine March 2010 June 2011
NCT00341783 Terminated Assessment of Biologic Parameters in Preparation for Future Malaria Vaccine Trials in Don gu Bougou, Mali July 2002 July 2005
NCT01082731 Terminated Phase 4 Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Falciparum in Pregnancy in Brazil November 2010 January 2012
NCT01290601 Terminated Phase 2 Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults September 15, 2003 January 10, 2005
NCT00811356 Terminated Phase 1 A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria December 11, 2008 March 30, 2009
NCT02880241 Terminated Phase 2 MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria October 20, 2017 September 24, 2018
NCT00331708 Terminated N/A Artesunate Plus Sulfadoxine-pyrimethamine Pharmacokinetics, Efficacy, Gametocytes Carriage and Birth Outcomes in Pregnant Women With Malaria April 2006 July 2007
NCT00497471 Terminated N/A RCT Iron Supplementation and Malaria Chemoprophylaxis for Prevention of Severe Anemia and Malaria in Tanzanian Infants February 1995 July 1999
NCT04148690 Terminated N/A Assessing the Impact of Group Antenatal Care on IPTp Uptake in Tanzania November 15, 2019 July 10, 2021
NCT02654730 Terminated Phase 2/Phase 3 Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia December 2015 December 2016
NCT00126217 Terminated Phase 4 Revaccination of Young Children With Bacille Calmette Guerin (BCG) Vaccine July 2002 September 2006
NCT01899820 Unknown status Phase 3 Evaluation of the Efficacy of Artemisinin Combination Therapy in Kenya April 2013 July 2015
NCT05317117 Unknown status N/A Evaluating the Clinical Performance and Usability of Novel Malaria RDTs in Brazil July 4, 2022 December 31, 2022
NCT00137566 Unknown status Phase 4 The Effect of Paracetamol in the Treatment of Non-severe Malaria in Children in Guinea-Bissau May 2004 January 2010
NCT05340153 Unknown status Phase 4 Efficacy and Safety of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Cameroon April 11, 2022 December 31, 2022
NCT05348746 Unknown status ERASE - Impact of COVID-19 on Malaria Control May 1, 2022 April 1, 2024
NCT01038063 Unknown status Phase 4 Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year Period October 2010 September 2013
NCT05354258 Unknown status N/A Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children June 16, 2022 September 2023
NCT01976325 Unknown status N/A Evaluating the Ottawa Malaria Decision Aid January 2014 November 2015
NCT04235361 Unknown status Mobile Point of Care Diagnostic Testing for Ebola Virus Disease in DRC January 15, 2021 July 30, 2021
NCT04238845 Unknown status N/A Assessment of a Combined Strategy of SMC + Nutrients Supplementation to Tackle Malaria and Malnutrition July 13, 2020 March 2022
NCT04241705 Unknown status N/A Evaluation of Targeted Mass Drug Administration for Malaria in Ethiopia January 20, 2020 January 20, 2022
NCT02866097 Unknown status N/A Integrated Community Case Management Study in Eastern Province, Zambia March 2016 September 2016
NCT01075945 Unknown status Phase 4 Dihydroartemisinin- Piperaquine Versus Artemether- Lumefantrine in the Treatment Uncomplicated Plasmodium Falciparum Malaria in Sudan February 2010 April 2010
NCT04245033 Unknown status Phase 4 Evaluation of the Implementation and Effectiveness of Intermittent Preventive Treatment for Malaria Using Dihydroartemisinin-piperaquine on Reducing Malaria Burden in School Aged Children in Tanzania July 20, 2020 December 31, 2021
NCT05400746 Unknown status Early Phase 1 A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK November 2, 2022 May 30, 2023
NCT01130155 Unknown status IMPACT2: Monitoring Interventions to Improve Artemisinin-based Combination Therapy (ACT) Access and Targeting May 2010 December 2012
NCT00712374 Unknown status Phase 4 Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal September 2008 July 2012
NCT00703066 Unknown status Phase 1 Safety and Immunogenicity of 30 and 100 µg of GMZ2 in Gabonese Children Aged 1-5 Years June 2008 August 2009
NCT02938975 Unknown status Phase 3 Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents for Malaria Prevention November 2017 June 2019
NCT01190371 Unknown status Phase 4 Have Malaria Infections in Kenya Become Less Responsive to Artemisinin Treatment? April 2011 December 2018
NCT00238017 Unknown status Phase 4 Efficacy and Safety of Amodiaquine and Amodiaquine-Artesunate October 2005 December 2005
NCT00209794 Unknown status Phase 1/Phase 2 IPTi in Mozambican Infants for Malaria Prevention September 2002 December 2005
NCT04570241 Unknown status N/A Mobilization at the Level of Schools on the Behavioral Change in Favor of the Fight Against Malaria in Mbandjock January 20, 2017 December 31, 2020
NCT02199951 Unknown status Introduction of Eurartesim® in Burkina Faso, Mozambique, Ghana and Tanzania September 2013 December 2014
NCT03074435 Unknown status Phase 3 Insecticide Resistance Management in Burkina Faso and Côte d'Ivoire April 2016 April 2019
NCT00652275 Unknown status Phase 2 Immunogenicity, Efficacy and Safety Study of an MSP3-LSP (Long Synthetic Peptide) Malaria Vaccine May 2008 December 2010
NCT00565071 Unknown status N/A Parasite-based Diagnosis for Malaria in Uganda: Feasibility and Cost-Effectiveness October 2006 December 2012
NCT04660110 Unknown status Phase 3 Household-level Impact of IPT of Malaria in Schoolchildren January 28, 2021 June 30, 2021
NCT00190281 Unknown status Contrast-Enhanced US of Spleen, Liver and Kidney August 2005
NCT04695886 Unknown status N/A Effectiveness of a Community-delivered Integrated Malaria Elimination (CIME) Model in Myanmar January 2021 July 2021
NCT00469651 Unknown status Phase 1 Phase Ib Trial of MSP3 LSP in Children in Tanzania October 2007 August 2008
NCT02297477 Unknown status Phase 4 The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in Cambodia December 2014 December 2021
NCT02298140 Unknown status N/A Providers' Compliance to Malaria Treatment November 2014 December 2015
NCT01361269 Unknown status Phase 2 Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria June 2011 December 2011
NCT04708496 Unknown status Phase 4 Optimizing Malaria Treatment for HIV-Malaria Co-infected Individuals January 18, 2021 March 2024
NCT04778813 Unknown status Phase 4 Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) June 1, 2021 June 1, 2022
NCT04816461 Unknown status Phase 4 Boosting the Impact of SMC Through Simultaneous Screening and Treatment of Roommates July 2021 June 2023
NCT02450630 Unknown status N/A Assessing the Effect of Strengthening Referral of Sick Children From the Private Health Sector and Its Impact on Referral Uptake in Uganda. May 2015 May 2017
NCT01459146 Unknown status Phase 4 Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana December 2010 November 2012
NCT01464125 Unknown status Phase 2 Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults November 2008 December 2011
NCT02482116 Unknown status A Comparison of Diagnostic Approaches for Malaria and Pneumonia August 2015 July 2017
NCT00452088 Unknown status Phase 1 A Phase Ib Trial of MSP 3 LSP in 1-2 Year Old Children in Burkina Faso April 2007 May 2008
NCT00442442 Unknown status Phase 3 Clinical Evaluation of Mosquito Coils to Control Malaria in China April 2007 December 2007
NCT03594084 Unknown status Malaria in Strasbourg University Hospital August 1, 2018 August 2019
NCT03599596 Unknown status Phase 1 Monthly Versus Two Doses of Ante-Natal Intermittent Preventive Treatment With Sulphadoxine-Pyrimethamine September 1, 2018 February 1, 2019
NCT01555255 Unknown status Malaria Rapid Diagnostic Tests (RDTs) in Pregnancy: Detection of Placental Malaria November 2010 December 2012
NCT05050825 Unknown status N/A Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal May 3, 2021 December 15, 2021
NCT01605786 Unknown status Phase 1/Phase 2 Trial for Malaria Vaccine Candidate, PfPEBS (P. Falciparum Pre-Erythrocytic and Blood Stage) May 2012 August 2013
NCT00938379 Unknown status Phase 3 Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR July 2009 June 2011
NCT01645254 Unknown status Phase 1 Phase 1b Malaria Clinical Trial Using Argemone Mexicana in Healthy Adults in Mali September 2012 November 2012
NCT05086887 Unknown status Infections in Migrants in Sweden - the Importance of Malaria and Other Parasitic Infections April 15, 2019 June 30, 2023
NCT05123378 Unknown status N/A Liberia National Community Health Assistant (NCHA) Program and Under-five Mortality May 1, 2018 August 1, 2022
NCT01697852 Unknown status Phase 4 The Combined Use of Indoor Residual Spraying (IRS) and Long-lasting Insecticidal Nets (LLINs) for Malaria Prevention January 2011 December 2012
NCT00431808 Unknown status Phase 1 Safety and Immunogenicity of Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) May 2007 June 2008
NCT00424944 Unknown status Phase 1 Safety of Recombinant Hybrid GMZ 2 [GLURP + MSP 3] Blood Stage Malaria Vaccine June 2007 August 2008
NCT00872963 Unknown status An Extended Follow up of a RTS,S/AS01E Malaria Vaccine Trial February 2009 August 2016
NCT02646410 Unknown status N/A Optimization of Seasonal Malaria Chemoprevention (SMC) Delivery August 2014 December 2018
NCT02653898 Unknown status Phase 4 Malaria Elimination Pilot Study in Military Forces in Cambodia January 2016 December 2021
NCT03960632 Unknown status Performance Evaluation of Malaria Plus RDTs June 2021 September 2021
NCT01805232 Unknown status Phase 4 Intravenous Artesunate and Malaria March 2013 July 2013
NCT01837992 Unknown status N/A Safety and Efficacy of Primaquine for P. Vivax May 2013 May 2015
NCT04053907 Unknown status N/A P. Falciparum Infection Dynamics and Transmission to Inform Elimination August 15, 2019 May 31, 2022
NCT00168948 Unknown status Phase 4 Intermittent Antimalaria Treatment With SP in African Children March 2003 August 2005
NCT00397449 Unknown status Phase 1 GMZ2-Aluminum Hydroxide Phase I, Tübingen October 2006 December 2007
NCT02721420 Unknown status Phase 3 Delivery of Malaria Chemoprevention in the Post-discharge Management of Children With Severe Anaemia in Malawi March 24, 2016 December 2019
NCT02739763 Unknown status Phase 1 Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA) May 2016 November 2020
NCT01002183 Withdrawn Phase 2 Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate
NCT03199755 Withdrawn Phase 2 Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria August 20, 2018 October 1, 2019
NCT01810731 Withdrawn Phase 2/Phase 3 Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya April 2014 April 2014
NCT00290420 Withdrawn Phase 4 Prevention of P. Vivax Malaria During Pregnancy in Bolivia March 2006 November 2007
NCT02900079 Withdrawn Use of Malaria Rapid Diagnostic Tests as a Decision Aid for the Management of Fever by International Travelers July 1, 2023 March 2024
NCT01082718 Withdrawn Phase 2/Phase 3 Pharmacokinetics of Mefloquine-Artesunate in Pregnant Women With Uncomplicated Plasmodium Falciparum Infection March 2010 October 2010
NCT02810613 Withdrawn Leiden University Medical Center Mini Donor Bank May 31, 2016 May 31, 2016
NCT00977899 Withdrawn Phase 1 Phase 1 Study of the Safety and Immunogenicity of a Malaria Transmission-blocking Pfs25-Pfs25 Conjugate Vaccine August 20, 2009 March 5, 2013
NCT04020653 Withdrawn Phase 2 A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria September 6, 2019 September 30, 2020
NCT01511601 Withdrawn Apheresis to Obtain Plasma and White Blood Cells in Malies December 20, 2011 July 28, 2016
NCT02640495 Withdrawn Artemisinin Resistance In Malaria Treated With IV Artesunate October 2015 December 2017
NCT02394522 Withdrawn N/A Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM) March 2016 April 2016
NCT01843491 Withdrawn Phase 1 A Phase I Clinical Trial Immunizing Healthy Adults With the NMRC-M3V-Ad-PfCA Vaccine to Generate Biologic Reagents June 2013 June 2014
NCT02793414 Withdrawn Diagnostic Utility of Volatile Organic Compounds in Human Breath for Acute Clinical Malaria in Ethiopia September 2016 January 2018
NCT03278808 Withdrawn Phase 2 Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis September 17, 2018 January 1, 2020
NCT02294214 Withdrawn N/A Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Tanzania February 2016 April 2016
NCT02793388 Withdrawn Phase 4 A Trial on Supervised Primaquine Use in Ethiopia September 2016 September 2017
NCT02294201 Withdrawn N/A Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Kenya June 2016 July 2016
NCT01785979 Withdrawn Phase 3 Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly January 2016 February 2017
Disase is a (Disease Ontology)
DOID:2789
Cross Reference ID (Disease Ontology)
EFO:0001068
Cross Reference ID (Disease Ontology)
GARD:6961
Cross Reference ID (Disease Ontology)
ICD10CM:B54
Cross Reference ID (Disease Ontology)
ICD9CM:084
Cross Reference ID (Disease Ontology)
MESH:D008288
Cross Reference ID (Disease Ontology)
NCI:C34797
Cross Reference ID (Disease Ontology)
ORDO:673
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:154374002
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0024530
Exact Synonym (Disease Ontology)
induced malaria
OrphaNumber from OrphaNet (Orphanet)
673
MeSH unique ID (MeSH (Medical Subject Headings))
D008288