Choroidal Neovascularization
Information
- Disease name
- Choroidal Neovascularization
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT01880788 | Completed | Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMD | November 2012 | August 2015 | |
| NCT01948830 | Completed | Phase 3 | Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMD | December 17, 2013 | November 19, 2015 |
| NCT02015351 | Completed | N/A | Intravitreal Bevacizumab for the Treatment of CNV in VKH Disease - A Prospective Study | September 2012 | October 2018 |
| NCT02260687 | Completed | Special Drug Use Investigation of EYLEA for Myopic Choroidal Neovascularization | December 5, 2014 | August 22, 2018 | |
| NCT02307682 | Completed | Phase 3 | Efficacy and Safety of RTH258 Versus Aflibercept - Study 1 | December 8, 2014 | March 28, 2018 |
| NCT02308215 | Completed | Retinal Therapy Guided by 3D OCT Image Analysis | July 2010 | July 5, 2018 | |
| NCT02358889 | Completed | Phase 2 | Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration | February 2015 | September 2016 |
| NCT02434328 | Completed | Phase 3 | Efficacy and Safety of RTH258 Versus Aflibercept - Study 2 | July 28, 2015 | March 8, 2018 |
| NCT02484690 | Completed | Phase 2 | A Proof-of-Concept Study of Faricimab (RO6867461) in Participants With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD) | August 11, 2015 | September 26, 2017 |
| NCT02821247 | Completed | Prospective Observational Study to Assess Effectiveness of Intravitreal Aflibercept in Patients With Wet Macular Degeneration in Greece | July 1, 2016 | December 13, 2019 | |
| NCT00304954 | Completed | Phase 2 | Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degeneration | February 2006 | January 2010 |
| NCT00305630 | Completed | Phase 2/Phase 3 | Neovascular Age Related Macular Degeneration (AMD), Periocular Corticosteroids, and Photodynamic Therapy (PDT) | July 2002 | November 2005 |
| NCT00331864 | Completed | Phase 3 | SUSTAIN - Study of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration | April 2006 | April 2008 |
| NCT00363168 | Completed | Phase 1 | Ranibizumab in Hemorrhagic Choroidal Neovascularization Trial | August 2006 | May 2009 |
| NCT00363714 | Completed | Phase 1/Phase 2 | A Dose Escalation Trial of an Intravitreal Injection of Sirna-027 in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD) | November 2004 | April 2007 |
| NCT00370786 | Completed | Phase 3 | Effect of Intravitreal Bevacizumab on Non -Age-Related Macular Degeneration (AMD) Related Choroidal Neovascularization (CNV) | November 2005 | February 2008 |
| NCT00395551 | Completed | Phase 1 | Safety Study of Ranibizumab Eye Injections to Treat Choroidal Neovascularization That Was Caused Other Than by Age-Related Macular Degeneration. | December 2005 | June 2009 |
| NCT03024424 | Completed | N/A | Value of Genetic Counseling and Testing for Patients Who Would Like to Know More About Their Personal Risk of AMD | March 2016 | August 10, 2017 |
| NCT01908816 | Completed | Phase 3 | An Open-label Extended Clinical Protocol of Ranibizumab to Evaluate Safety and Efficacy in Rare VEGF Driven Ocular Diseases. | September 26, 2013 | January 8, 2016 |
| NCT00406250 | Completed | Phase 1 | Intravitreal Bevacizumab in Agioid Streaks | November 2006 | May 2009 |
| NCT00021736 | Completed | Phase 2/Phase 3 | Phase II/III Study of Anti-VEGF in Neovascular AMD | July 2001 | July 2002 |
| NCT00407719 | Completed | Phase 1 | Bevicizumab (Avastin) Infusion for Choroidal Neovascularization (CNV) Not Associated With Age-Related Macular Degeneration (AMD) | June 2005 | May 2008 |
| NCT00417703 | Completed | Intraocular Pressure Immediately Following Intravitreous Injection of Ranibizumab | January 2007 | January 2008 | |
| NCT04782271 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops | March 17, 2021 | December 21, 2021 |
| NCT00417846 | Completed | Age-related Macular Degeneration: Detection of Onset of New Choroidal Neovascularization (AMD DOC Study) | January 2007 | August 2009 | |
| NCT00426998 | Completed | Phase 2 | Combination Bevacizumab and Verteporfin (Two Different Sequences of Treatment)in Neovascular AMD | April 2006 | |
| NCT00429962 | Completed | Phase 3 | Study Comparing Ranibizumab Monotherapy With Combined Verteporfin Therapy in Subfoveal CNV | July 2006 | June 2008 |
| NCT00436553 | Completed | Phase 3 | Efficacy/Safety of Verteporfin Photodynamic Therapy and Ranibizumab Compared With Ranibizumab in Patients With Subfoveal Choroidal Neovascularization | February 2007 | October 2009 |
| NCT00470678 | Completed | Phase 3 | EXTEND III - Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD) | June 2007 | November 2008 |
| NCT00473642 | Completed | Phase 4 | Reduced Fluence Photodynamic Therapy (PDT) With Visudyne in Combination With Lucentis for Age-Related Macular Degeneration | May 2007 | April 2010 |
| NCT00492284 | Completed | Phase 2 | Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL) | July 2007 | May 2010 |
| NCT00001615 | Completed | Phase 1 | Phase I Study of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular Degeneration | July 1997 | May 2000 |
| NCT00510965 | Completed | Phase 2 | Ranibizumab to Treat Choroidal Neovascularization (CNV) in Patients With Pseudoxanthoma Elasticum (PXE) | August 2007 | April 2010 |
| NCT00511706 | Completed | Phase 2 | Safety and Efficacy of a New Treatment as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) Treatment in Patients With Age-Related Macular Degeneration (AMD) | November 1, 2007 | March 1, 2009 |
| NCT00533520 | Completed | Phase 4 | Evaluation of Dosing Interval of Higher Doses of Ranibizumab | September 2007 | November 2013 |
| NCT04455399 | Completed | N/A | Time Efficiency Comparison of Two IntraVitreal Injection Techniques | November 9, 2020 | January 9, 2021 |
| NCT00570193 | Completed | Phase 1/Phase 2 | Photodynamic and Pharmacologic Treatment of CNV | December 2006 | June 2011 |
| NCT00242580 | Completed | Phase 3 | A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of Intravitreal Triamcinolone Acetonide and the Verteporfin Therapy Plus Intravitreal Pegaptanib | September 2005 | |
| NCT00604071 | Completed | Sensitivity of the Home Macular Perimeter (HMP) | November 2007 | November 2008 | |
| NCT00251459 | Completed | Phase 3 | A Study to Evaluate Ranibizumab in Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD) | November 2005 | September 2007 |
| NCT00729846 | Completed | Phase 2 | Bevacizumab in Combination With Visudyne Photodynamic Therapy (PDT) | May 2006 | July 2009 |
| NCT05662943 | Completed | Outcomes of Tolerating Subretinal Fluid in Type 1 MNV and PCV | December 5, 2022 | November 30, 2023 | |
| NCT00775411 | Completed | Phase 2 | Safety and Efficacy of a New Therapy as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) in Subjects With Wet Age-Related Macular Degeneration (AMD) | November 2008 | April 2010 |
| NCT04075188 | Completed | N/A | Treatment of Polypoidal Choroidal Vasculopathy in Pachychoroid | September 18, 2017 | July 13, 2019 |
| NCT03793400 | Completed | Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth Factor | March 13, 2018 | December 28, 2018 | |
| NCT00967850 | Completed | Phase 3 | Efficacy and Safety of Intravitreal Bevacizumab in the Treatment of Choroidal Neovascular Membranes Associated to High Myopia | April 2008 | June 2011 |
| NCT00008515 | Completed | Phase 1 | Fluocinolone Implant to Treat Macular Degeneration | January 2001 | December 2001 |
| NCT01025063 | Completed | Use of Spectral OCT in Combination Therapy | January 2008 | December 2009 | |
| NCT01136252 | Completed | Phase 2 | Intravitreal Adalimumab in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration | May 2010 | October 2011 |
| NCT01175395 | Completed | Phase 1/Phase 2 | 20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD) | September 2010 | January 2013 |
| NCT03409250 | Completed | Phase 4 | SD-OCT-guided Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Myopia | June 2011 | July 2014 |
| NCT01256632 | Completed | N/A | Evaluation of the Effect of Vitreous Composition Determined by Ultrasound and Optical Coherence Tomography (OCT) on Ranibizumab Therapy | October 2007 | October 2010 |
| NCT01298440 | Completed | Bevacizumab Effect on Blood Velocity | January 2008 | June 2008 | |
| NCT01334294 | Completed | Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related Macular Degeneration | April 2011 | March 2014 | |
| NCT03393767 | Completed | Phase 4 | Time Course of Activity Signs at SD-OCT High Frequency Intravitreal Ranibizumab Treatment in CNV Due to AMD | December 2010 | December 2016 |
| NCT01423149 | Completed | Phase 2 | Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascularization Secondary to Pathologic Myopia | March 2005 | January 2007 |
| NCT01445899 | Completed | Phase 2 | PF-04523655 Dose Escalation Study, and Evaluation of PF-04523655 With/Without Ranibizumab in Diabetic Macular Edema (DME) | February 2012 | November 2013 |
| NCT03042871 | Completed | Phase 4 | Dosing Strategy of Intravitreal Ranibizumab for Pathological Myopia Choroidal Neovascularization | April 2015 | July 2018 |
| NCT01570790 | Completed | Phase 1/Phase 2 | Combretastatin A4 Phosphate in Patients With Neovascular Age-Related Macular Degeneration | May 2003 | June 2005 |
| NCT01578720 | Completed | Phase 1 | Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis Syndrome | June 2012 | March 2015 |
| NCT01628354 | Completed | Phase 4 | Study to Investigate the Safety and Efficacy of Ranibizumab in Patients With Choroidal Neovascularisation Due to Causes Other Than Age Related Macular Degeneration | February 2008 | April 2010 |
| NCT06243406 | Not yet recruiting | Study on the Biomarkers of Anti-VEGF Treatment for Choroidal Neovascularization | February 10, 2024 | October 2024 | |
| NCT05494775 | Recruiting | N/A | Effect of Corona Virus on Intravitreal Injections | February 1, 2019 | July 30, 2023 |
| NCT00417833 | Terminated | Phase 2/Phase 3 | Multifocal Electrophysiologic Findings After Intravitreal Bevacizumab(Avastin)Treatment | December 2005 | July 2006 |
| NCT00102115 | Terminated | Phase 1 | Study of Talaporfin Sodium Photodynamic Therapy to Treat Advanced Age Related Macular Disease | December 2004 | January 2006 |
| NCT00272766 | Terminated | N/A | Macugen for Histoplasmosis | February 2006 | May 2007 |
| NCT00406744 | Terminated | Phase 3 | Efficacy of Retreatments With Intravitreal Bevacizumab | May 2006 | November 2006 |
| NCT00433017 | Terminated | Phase 2/Phase 3 | Verteporfin Photodynamic Therapy Administered in Conjunction With Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD) | May 2007 | July 2009 |
| NCT00509548 | Terminated | Phase 2 | Open-Label, Pilot Study of TG100801 in Patients With Choroidal Neovascularization Due to AMD | July 2007 | March 2008 |
| NCT00599820 | Terminated | Phase 3 | Use of Intravitreal Bevacizumab in Eyes With Choroidal Neovascularization Secondary to Angioid Streaks | November 2005 | May 2006 |
| NCT00712491 | Terminated | Phase 1/Phase 2 | Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration | September 2008 | March 2010 |
| NCT00766337 | Terminated | Phase 2 | Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration | December 2008 | March 2010 |
| NCT01021956 | Terminated | Phase 2 | Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMD | June 2010 | January 2014 |
| NCT02857894 | Terminated | Genetic Factors of Idiopathic Polypoidal Vasculopathies in the ATM Gene (Ataxia Telangiectasia Mutated) | November 5, 2015 | October 23, 2018 | |
| NCT03105609 | Terminated | Enhancing the Lucentis (Ranibizumab) Management of Choroidal Neovascular Membranes With Hyperspectral Imaging | November 14, 2017 | December 1, 2018 | |
| NCT03452527 | Terminated | Phase 2 | Open-Label Study of Intravitreal ICON-1 in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD) | March 26, 2018 | April 25, 2019 |
| NCT00000158 | Unknown status | Phase 3 | Macular Photocoagulation Study (MPS) | February 1979 | |
| NCT05055973 | Unknown status | OCTA Insights in CNVM, Morphological Characteristics and Correlation With Structural OCT. | October 2021 | December 2022 | |
| NCT02486484 | Unknown status | Phase 2 | Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection | March 2015 | December 2019 |
| NCT00260403 | Unknown status | Phase 2/Phase 3 | TTT Versus PDT for Treatment of Choroidal Neovascularization in Age-Related Macular Degeneration | June 2003 | January 2008 |
| NCT02934841 | Unknown status | Phase 2 | Conbercept in Choroidal Neovascularization Secondary to Uveitis | November 2016 | November 2018 |
| NCT00100087 | Unknown status | Phase 1/Phase 2 | Safety Study for Treatment of Wet Macular Degeneration Using the TheraSight(TM) Ocular Brachytherapy System | October 2004 | |
| NCT00855608 | Unknown status | Phase 1 | Intravitreal Adalimumab in Refractory Diabetic Retinopathy, Choroidal Neovascularization or Uveitis: A Pilot Study | March 2009 | March 2013 |
| NCT03838679 | Unknown status | Imaging of the Angiofibrotic Switch in Neovascular AMD | May 1, 2019 | April 28, 2022 | |
| NCT01531842 | Unknown status | N/A | A Research Study to Evaluate the Effects of Repeated Intravitreal Injections on Bacteria Around the Eye | August 2011 | August 2013 |
| NCT04439708 | Unknown status | Biomarkers and Choroidal Neovascularization | June 15, 2020 | April 1, 2022 | |
| NCT00568191 | Unknown status | Stratus Versus Cirrus OCT in AMD | October 2007 | December 2007 | |
| NCT04488887 | Unknown status | OCTA Metrics Repeatability and Reproducibility in Different Disorders | August 1, 2020 | July 31, 2021 | |
| NCT00813514 | Withdrawn | N/A | Does Vascular Endothelial Growth Factor (VEGF) or Complement Factor H Gene Polymorphism Play a Role in the Treatment Success With VEGF Inhibitors in Patients With Choroidal NeoVascularization (CNV)? | January 2009 | November 2014 |
| NCT01336907 | Withdrawn | Comparison Between Home Macular Perimeter and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV) | |||
| NCT01256580 | Withdrawn | N/A | Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD | August 2010 | September 2013 |
| NCT01666236 | Withdrawn | Phase 4 | Triple Treatment for Detachment of Retinal Pigment Epithelium Secondary to Polypoidal Choroidal Vasculopathy | September 2012 | September 2014 |
| NCT00403156 | Withdrawn | Phase 1 | Imatinib Mesylate Combined With Intravitreal Ranibizumab in the Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration | November 2006 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0011506
- MeSH unique ID (MeSH (Medical Subject Headings))
- D020256