Respiratory Distress Syndrome, Adult
Information
- Disease name
- Respiratory Distress Syndrome, Adult
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03111212 | Completed | Phase 3 | Iloprost in Acute Respiratory Distress Syndrome | June 25, 2019 | August 14, 2021 |
| NCT00004494 | Completed | Phase 1 | Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis | September 1998 | |
| NCT00029328 | Completed | Phase 1/Phase 2 | Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation | September 2001 | September 2003 |
| NCT00036062 | Completed | Phase 1/Phase 2 | A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury | August 2001 | December 2002 |
| NCT00094406 | Completed | Phase 1 | Carbon Monoxide to Prevent Lung Inflammation | October 13, 2004 | March 11, 2010 |
| NCT06430619 | Completed | Can Novel Oxygenation Indices Guide the Diagnosis of Acute Respiratory Distress Syndrome | June 1, 2012 | May 1, 2024 | |
| NCT00113685 | Completed | N/A | Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury | April 2003 | March 2007 |
| NCT00141726 | Completed | Phase 2 | Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant | October 2003 | February 2009 |
| NCT00157144 | Completed | Australia and New Zealand Adult Extracorporeal Membrane Oxygenation (ECMO) Audit 2005 | October 2004 | August 2006 | |
| NCT00201409 | Completed | Phase 2 | A Randomized Trial of GM-CSF in Patients With ALI/ARDS | July 2004 | June 2009 |
| NCT00217880 | Completed | N/A | Significance of Biological Markers in Patients With Acute Lung Injury/Acute Respiratory Disease | July 2004 | June 2009 |
| NCT06199141 | Completed | Multi-drug Resistant Gram-negative Bacteria and Veno-venous Extracorporeal Membrane Oxygenation (ECMO) | January 1, 2017 | December 31, 2023 | |
| NCT00236262 | Completed | N/A | Effect of Positive Expiratory Pressure on Right Ventricular Function in Patients With Respiratory Distress Syndrome | October 2005 | September 2006 |
| NCT00267241 | Completed | N/A | Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) Patients | December 2005 | November 2014 |
| NCT00300248 | Completed | Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome | October 2004 | October 2012 | |
| NCT06159465 | Completed | Utility of Defining ARDS and Past and Current Definitions of ARDS | December 13, 2023 | April 15, 2024 | |
| NCT03188770 | Completed | Practice of Ventilation in Middle-Income Countries | November 1, 2017 | January 29, 2019 | |
| NCT02961166 | Completed | Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients | January 2012 | May 2016 | |
| NCT00351533 | Completed | Phase 2 | A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI) | July 2006 | August 2009 |
| NCT05210881 | Completed | Weaning From Nasal High Flow Therapy | January 1, 2019 | August 31, 2021 | |
| NCT00399581 | Completed | Phase 2 | Comparison of Two Methods of High Frequency Oscillatory Ventilation in Individuals With Acute Respiratory Distress Syndrome | November 2006 | June 2009 |
| NCT00416260 | Completed | Phase 1/Phase 2 | Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome | July 2006 | September 2007 |
| NCT05083130 | Completed | N/A | Awake Prone Positioning in Moderate to Severe COVID-19 | March 8, 2022 | May 1, 2023 |
| NCT00431158 | Completed | N/A | ARDSnet Protocol vs. Open Lung Approach in ARDS | January 2007 | March 2013 |
| NCT00455767 | Completed | Phase 2 | Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients | July 2006 | September 2007 |
| NCT00458926 | Completed | Enhancing Utilization of Non-Invasive Positive Pressure Ventilation in Critical Care | November 2003 | December 2009 | |
| NCT04744090 | Completed | Phase 2 | Roflumilast as add-on Therapy in Early Cases of ARDS | March 21, 2021 | January 1, 2022 |
| NCT04710329 | Completed | High-Dose Vitamin C Treatment in Critically Ill COVID-19 Patients | January 16, 2021 | February 10, 2021 | |
| NCT00548795 | Completed | Viral-Related Neutrophil Response and Condition Severity in People With ARDS | August 2007 | July 2012 | |
| NCT00605527 | Completed | Understanding the Role of Genes and Biomarkers in the Inflammation and Blood Clotting Process in Children With Acute Lung Injury | November 2007 | December 2016 | |
| NCT00605696 | Completed | Phase 2 | Early Insulin and Development of ARDS | April 2008 | September 2013 |
| NCT04582201 | Completed | Phase 1/Phase 2 | Evaluate the Safety of agenT-797 in Participants With Moderate to Severe Difficulty Breathing Secondary to SARS-CoV-2 | September 21, 2020 | April 23, 2023 |
| NCT00000579 | Completed | Phase 3 | Acute Respiratory Distress Syndrome Clinical Network (ARDSNet) | September 1994 | July 2004 |
| NCT00719446 | Completed | Evaluating Health Outcomes and QOL After ALI Among Participants of the ALTA, OMEGA, EDEN, and SAILS ARDS Network Trials | October 2007 | October 2014 | |
| NCT00883948 | Completed | Phase 3 | Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) | December 2007 | May 2011 |
| NCT04510662 | Completed | Phase 2 | Telmisartan in Respiratory Failure Due to COVID-19 | August 12, 2020 | May 25, 2021 |
| NCT04388826 | Completed | Phase 2 | COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111 | June 18, 2020 | August 13, 2021 |
| NCT01119872 | Completed | N/A | Pilot Study of Positive-End Expiratory Pressure in Acute Respiratory Distress Syndrome | January 2003 | December 2008 |
| NCT04378582 | Completed | Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU | May 7, 2020 | August 5, 2020 | |
| NCT01167621 | Completed | Changes in Refractory Acute Respiratory Distress Syndrome (ARDS) Patients Under High Frequency Oscillation-ventilation | September 2010 | September 2012 | |
| NCT01256333 | Completed | Optimization of Arterial Oxygen Transport by Positive End-expiratory Pressure Variation in Acute Respiratory Distress Syndrome | January 2011 | ||
| NCT01374022 | Completed | N/A | ART - Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial | June 2011 | December 2017 |
| NCT04345887 | Completed | Spironolactone in Covid-19 Induced ARDS | May 5, 2020 | July 5, 2020 | |
| NCT04297397 | Completed | Personalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit | February 20, 2020 | May 31, 2022 | |
| NCT01468142 | Completed | Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure | February 2012 | December 2016 | |
| NCT01601223 | Completed | Local Assessment of Ventilatory Management During General Anesthesia for Surgery | January 2013 | November 2013 | |
| NCT04157946 | Completed | The Role of Morphological Phenotype in ARDS | August 7, 2017 | July 20, 2019 | |
| NCT01743105 | Completed | N/A | Reproductibility of TM-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in the ER | August 2013 | January 2014 |
| NCT03969914 | Completed | PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury | May 1, 2019 | June 15, 2020 | |
| NCT03818854 | Completed | Phase 2 | Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome | November 26, 2019 | September 30, 2023 |
| NCT02097641 | Completed | Phase 2 | Human Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (START) | March 15, 2014 | February 9, 2018 |
| NCT03807804 | Completed | Phase 2 | Efficacy and Safety Study of HLCM051(MultiStem®) for Pneumonic Acute Respiratory Distress Syndrome | January 1, 2019 | December 14, 2021 |
| NCT03712215 | Completed | N/A | STUDY OF ELECTRICAL STIMULATION IN PULMONARY FUNCTION IN INTENSIVE CARE UNIT | September 4, 2018 | January 31, 2019 |
| NCT02273687 | Completed | N/A | Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department | October 29, 2014 | September 29, 2017 |
| NCT03539783 | Completed | Identifying PARDS Endotypes | April 1, 2018 | September 5, 2022 | |
| NCT03337373 | Completed | Phase 4 | The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium | December 15, 2017 | August 31, 2018 |
| NCT02439151 | Completed | N/A | New Lung Ventilation Strategies Guided by Transpulmonary Pressure in VV-ECMO for Severe ARDS | May 1, 2015 | June 25, 2020 |
| NCT03202394 | Completed | Phase 2 | Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS | August 5, 2017 | June 15, 2020 |
| NCT02664090 | Completed | Hemodynamic Assessment With Trans-esophageal Doppler (TED) During Prone Ventilation in ARDS Patients | January 20, 2016 | January 18, 2017 | |
| NCT02732041 | Completed | Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome | May 25, 2016 | February 2019 | |
| NCT02759770 | Completed | Risk Factors and Prediction Score of ARDS After Cardiac Surgery | July 1, 2017 | September 30, 2017 | |
| NCT02799940 | Completed | Abnormalities in Lung Computed Tomography and Physiological Alterations in Patients With Acute Respiratory Distress Syndrome | August 2016 | May 19, 2019 | |
| NCT05604430 | Enrolling by invitation | Pre-hospital Ventilation Clinical Study | June 30, 2022 | June 30, 2024 | |
| NCT05081895 | Enrolling by invitation | Ventilation and Perfusion in the Respiratory System | August 19, 2021 | July 2024 | |
| NCT04545424 | Recruiting | Phase 2 | Trial of Therapeutic Hypothermia in Patients With ARDS | June 29, 2021 | September 30, 2025 |
| NCT03368092 | Recruiting | Phase 3 | Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma | March 4, 2019 | December 1, 2024 |
| NCT03709199 | Recruiting | Long Term Follow up of Children Enrolled in the REDvent Study | October 1, 2018 | May 1, 2026 | |
| NCT04012073 | Recruiting | Phase 3 | Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome | November 1, 2022 | April 30, 2025 |
| NCT04139733 | Recruiting | Early Use of Prone Position in ECMO for Severe ARDS | November 1, 2019 | October 30, 2024 | |
| NCT04228471 | Recruiting | N/A | Early PReserved SPONtaneous Breathing Activity in Mechanically Ventilated Patients With ARDS (PReSPON) | February 8, 2020 | July 2024 |
| NCT05715762 | Recruiting | Determine the Effects of Prone Positioning and NO in COVID-19 ARDS by EIT | December 21, 2022 | December 31, 2023 | |
| NCT06174636 | Recruiting | N/A | Lung Overdistension and Abdominal Pressure Rise | June 20, 2023 | June 2025 |
| NCT06203405 | Recruiting | N/A | The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial | December 22, 2023 | June 30, 2025 |
| NCT04382391 | Terminated | N/A | Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms | May 15, 2020 | April 13, 2023 |
| NCT04028336 | Terminated | N/A | The Strategy of "Pulmonary Opening by Titration of Positive End-expiratory Pressure" Means of a Pulmonary Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome: for Which Patients? | December 20, 2019 | January 7, 2021 |
| NCT04395105 | Terminated | Phase 3 | Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial | May 21, 2020 | May 21, 2021 |
| NCT02622724 | Terminated | Phase 3 | Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Patients Having Acute Respiratory Distress Syndrome (ARDS) | December 23, 2015 | May 23, 2018 |
| NCT00944437 | Terminated | N/A | Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet | May 2008 | July 2010 |
| NCT02370095 | Terminated | Phase 2 | Treprostinil Sodium Inhalation for Patients At High Risk for ARDS | February 2015 | November 7, 2017 |
| NCT02252094 | Terminated | N/A | Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS | May 22, 2017 | May 31, 2019 |
| NCT00682500 | Terminated | Phase 3 | Calfactant for Direct Acute Respiratory Distress Syndrome | May 2008 | February 2011 |
| NCT00609180 | Terminated | Phase 3 | Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study) | December 2007 | April 2009 |
| NCT00112164 | Terminated | Phase 2 | Activated Protein C to Treat Acute Lung Injuries | January 2005 | February 2007 |
| NCT01461889 | Terminated | Phase 3 | INR-Triggered Transfusion In GI Bleeders From ER | July 2011 | August 2015 |
| NCT04778059 | Terminated | Phase 2 | Safety and Efficacy of USB002 for Respiratory Distress Due to COVID-19 | July 27, 2021 | May 10, 2022 |
| NCT00434993 | Terminated | Phase 2/Phase 3 | Drug Study of Albuterol to Treat Acute Lung Injury | August 2007 | November 2008 |
| NCT00357929 | Terminated | N/A | Weaning From Mechanical Ventilation Using Permissive Hypercarbia | August 2006 | June 14, 2007 |
| NCT02895373 | Terminated | Phase 2 | PGE1 as Additive Anticoagulant in ECMO-Therapy | July 2016 | July 2021 |
| NCT04347980 | Terminated | Phase 3 | Dexamethasone Treatment for Severe Acute Respiratory Distress Syndrome Induced by COVID-19 | April 17, 2020 | August 7, 2020 |
| NCT00233207 | Terminated | Phase 2 | IC14 Antibodies to Treat Individuals With Acute Lung Injury | September 2005 | June 2007 |
| NCT03424798 | Unknown status | Measuring Heart and Lung Function in Critical Care | October 21, 2017 | September 2020 | |
| NCT03788096 | Unknown status | N/A | Peer Support for Post Intensive Care Syndrome Self-Management | April 20, 2020 | January 27, 2021 |
| NCT02112500 | Unknown status | Phase 2 | Mesenchymal Stem Cell in Patients With Acute Severe Respiratory Failure | February 2014 | December 2016 |
| NCT01992237 | Unknown status | Measuring Energy Expenditure in ECMO (Extracorporeal Membrane Oxygenation) Patients | October 2013 | June 2018 | |
| NCT01990456 | Unknown status | N/A | Strategies for Optimal Lung Ventilation in ECMO for ARDS: The SOLVE ARDS Study | September 2014 | |
| NCT03971331 | Unknown status | N/A | The Value of Combined Critical Care Ultrasound and PAC Monitor Oriented Therapy Protocol to Patients of ARDS With ACP | July 1, 2019 | December 30, 2021 |
| NCT01716962 | Unknown status | Effects of Positive End-expiratory Pressure and Tidal Volume on Fluid Responsiveness of Acute Respiratory Distress Syndrome | November 2012 | ||
| NCT01391481 | Unknown status | Phase 2 | Perfluorocarbon (PFC) Inhalation Treatment of Acute Lung Injury/Acute Respiratory Distress Syndrome | August 2011 | April 2015 |
| NCT01165528 | Unknown status | N/A | Adaptive Support Ventilation in Acute Respiratory Distress Syndrome (ARDS) | January 2010 | |
| NCT01070654 | Unknown status | N/A | Inflammatory Effects of a Lung Recruitment Manoeuvre | June 2010 | December 2010 |
| NCT04516486 | Unknown status | Coronavirus Studied by Metagenomics in ARDS COVID-19 Patients | March 9, 2020 | December 31, 2020 | |
| NCT04520815 | Unknown status | Prevalence and Kinetics of Diaphragmatic Dysfunction in Elderly Patients With Acute Respiratory Distress | June 24, 2020 | June 30, 2022 | |
| NCT00542737 | Unknown status | N/A | Evaluating a Web-Based Ventilator Management Educational Program for Clinicians (The Lung Injury Knowledge Network [LINK] Study) | February 2009 | July 2014 |
| NCT00465374 | Unknown status | Phase 3 | A Validation/Interventional Study on Stress Index in Predicting Mechanical Stress in ARDS Patients | October 2002 | |
| NCT00429637 | Unknown status | Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients | December 2004 | January 2009 | |
| NCT02892799 | Unknown status | N/A | Non-invasive Fluid Management | November 12, 2015 | December 2020 |
| NCT03236272 | Unknown status | Establishment of a Biomarkers-based Early Warning System of Acute Respiratory Distress Syndrome (ARDS) | September 15, 2017 | December 31, 2020 | |
| NCT02342756 | Unknown status | N/A | Esophageal Pressure-Guided Optimal PEEP/mPaw in CMV and HFOV: The EPOCH Study | January 2015 | December 2017 |
| NCT00308022 | Withdrawn | Phase 2/Phase 3 | Comparison Study of High Frequency Percussive Ventilation With Conventional Ventilation | January 2006 | December 31, 2009 |
| NCT00319631 | Withdrawn | Role of Vascular Endothelial Growth Factor (VEGF) in Acute Lung Injury/Adult Respiratory Distress Syndrome (ARDS) | January 2006 | January 2017 | |
| NCT04508933 | Withdrawn | Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients | September 1, 2020 | December 31, 2020 | |
| NCT03376854 | Withdrawn | Phase 2 | Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS | May 1, 2018 | April 27, 2021 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D012128