Severe Sepsis

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Information
Disease name
Severe Sepsis
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT01162109 Active, not recruiting Phase 1 Zinc Therapy in Critical Illness September 2010 December 2024
NCT05296590 Active, not recruiting Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without Bacteremia July 1, 2021 June 2026
NCT05060250 Active, not recruiting Symphony IL-6 Cutoff Establishment Study for Patients at Risk of Severe Sepsis Due to COVID-19 August 31, 2021 December 31, 2024
NCT00207844 Completed Phase 2 Selenium, as Sodium Selenite, in the Treatment of Septic Shock January 2002 January 2005
NCT00273728 Completed Phase 4 BaSES Trial: Basel Starch Evaluation in Sepsis May 2005 May 2011
NCT00329680 Completed Phase 4 The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis June 2007 October 2009
NCT00334828 Completed Phase 3 ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis June 2006
NCT00372502 Completed N/A Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation January 2007 December 2008
NCT00386425 Completed Phase 2 Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated) November 2006 August 2009
NCT00398736 Completed A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.
NCT00407823 Completed N/A Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring January 2004 August 2005
NCT00448968 Completed The Utility of Ischemia Modified Albumin (IMA) in Sepsis March 2007 September 2007
NCT00615017 Completed Phase 2 AZD9773 Dose Escalation Study January 2008 July 2009
NCT00148278 Completed Phase 2/Phase 3 Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock October 1999 December 2005
NCT00159952 Completed Phase 2/Phase 3 Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock November 2004 November 2007
NCT01523717 Completed Procalcitonin Monitoring Sepsis Study December 2011 March 2014
NCT01556373 Completed Effects of Acute Systemic Inflammation on Arterial Stiffness and Microcirculation. February 23, 2012 April 16, 2015
NCT01568853 Completed N/A A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis November 2011 March 2012
NCT01598831 Completed Phase 3 Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy October 29, 2012 February 28, 2019
NCT01626612 Completed Phase 3 De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis February 2012 July 2013
NCT01649440 Completed Sepsis Metabolomics July 2010 March 2012
NCT01663701 Completed N/A Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia October 2012 January 2014
NCT01692847 Completed Examination of the Impact of Better Surveillance and Communication of Patient Deterioration on Patient Related Outcomes October 2012 February 2016
NCT01726595 Completed Ultrasound Measurement of Reactive Hyperemia in Critical Care January 2013 December 2019
NCT01739361 Completed Phase 2 Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis April 2013 December 2013
NCT01804764 Completed Lotta Alla Sepsi Ospedaliera - Fighting Hospital Sepsis May 2011 June 2013
NCT01806428 Completed Activated Protein C and Microcirculation July 2009 August 2011
NCT01867905 Completed Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock March 1, 2014 April 10, 2019
NCT01919138 Completed Outcomes of Severe Sepsis Patients in Surgical Intensive Care Units July 2013 June 2014
NCT01929772 Completed German Lactat Clearance in Severe Sepsis September 2012 April 2015
NCT01932814 Completed Acute Kidney Injury in Septic Critically Ill Patients : Are Aminoglycosides Really Harmful? September 2012 August 2013
NCT01943747 Completed International Multicentre Prevalence Study on Sepsis November 2013 January 2014
NCT01945983 Completed N/A Early Use of Norepinephrine in Septic Shock Resuscitation October 3, 2013 August 2017
NCT01968746 Completed The AVERT Sepsis Investigation August 2012 April 2015
NCT01988428 Completed N/A Prehospital Antibiotics Against Sepsis Trial June 2014 June 2017
NCT02025660 Completed Phase 2/Phase 3 Efficacy of Mw Vaccine in Treatment of Severe Sepsis August 2013 March 2014
NCT02026856 Completed Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis December 2013 December 2013
NCT02034240 Completed Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis? January 2014 April 2015
NCT02041663 Completed N/A Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis March 5, 2012 July 11, 2018
NCT02157259 Completed An Observational Study of the Causes, Management, and Outcomes of Community-acquired Sepsis and Severe Sepsis in Southeast Asia December 2013 February 2016
NCT02180009 Completed Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis December 2013 December 2015
NCT02217592 Completed Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast Thailand May 20, 2012 February 28, 2017
NCT02246595 Completed Phase 2 Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction April 2014 December 2015
NCT02346331 Completed N/A Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya January 2015 September 2016
NCT02354742 Completed N/A Echo vs. EGDT in Severe Sepsis and Septic Shock December 2014 October 2017
NCT02361528 Completed Phase 3 GM-CSF to Decrease ICU Acquired Infections September 14, 2015 June 1, 2018
NCT02370186 Completed The Role of Dysfunctional HDL in Severe Sepsis February 2015 March 12, 2017
NCT02376842 Completed N/A Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert November 2014 March 2015
NCT02393781 Completed Adrenomedullin and Outcome in Severe Sepsis and Septic Shock June 2015 June 2016
NCT02413541 Completed N/A The Pilot Study of the Efficacy of Polymyxin-B Hemoperfusion in Critically Ill Patients With Severe Sepsis January 2015 August 30, 2017
NCT02430142 Completed Microcirculatory Oxygen Uptake in Sepsis April 2015 August 1, 2017
NCT02539147 Completed Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe Sepsis September 2014 December 2014
NCT02569086 Completed Piperacillin PK Analysis in Severe Sepsis Patients November 1, 2015 June 30, 2016
NCT02589431 Completed Comparison of Total, Salivary and Calculated Free Cortisol Levels in Patients With Severe Sepsis June 2009 June 2011
NCT02655133 Completed Phase 2 Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients. January 2016 January 1, 2018
NCT02734550 Completed N/A (1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in Sepsis September 12, 2016 September 17, 2019
NCT02739152 Completed TRIAGE: TRIage of Sepsis At emerGency dEpartment April 2015 March 2018
NCT02739373 Completed Phase 1 Pharmacokinetics, Safety, Tolerability and Pharmacodynamics of BMS-986189 in Healthy Subjects April 18, 2016 December 14, 2016
NCT02777606 Completed N/A The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis June 2016 April 2019
NCT02794025 Completed N/A The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis January 2010 January 2013
NCT02820675 Completed N/A Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions August 2015 July 2019
NCT02960854 Completed Phase 1 A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock. December 7, 2016 January 5, 2018
NCT02973243 Completed The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III October 5, 2016 February 28, 2017
NCT03015454 Completed N/A An Algorithm Driven Sepsis Prediction Biomarker December 2016
NCT03029039 Completed Platelet-associated Inflammation in Severe Sepsis February 2, 2017 July 5, 2019
NCT03037281 Completed Release of Nociceptin From Granulocytes in Sepsis April 7, 2016 June 30, 2019
NCT03048994 Completed N/A Glutamine Supplementation in Critically Ill Patients With Severe Sepsis January 2011 June 2013
NCT03077672 Completed Mitochondrial DNA as a Biomarker of Sepsis Severity February 10, 2017 December 22, 2020
NCT03137446 Completed N/A Restrictive Intravenous Fluids Trial in Sepsis April 20, 2017 March 30, 2018
NCT03235193 Completed N/A Predictive algoRithm for EValuation and Intervention in SEpsis July 1, 2017 August 30, 2017
NCT03246893 Completed N/A Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients May 1, 2017 October 31, 2019
NCT03249246 Completed Epidemiology of Sepsis in Turkish ICUs. January 27, 2016 February 27, 2016
NCT03588325 Completed Evaluation of MDW for Early Detection of Sepsis, Clinical Validity August 8, 2018 August 30, 2019
NCT03641534 Completed Monitoring of Perfusion in Sepsis and Malaria June 4, 2018 September 26, 2019
NCT03655626 Completed N/A Implementation and Evaluations of Sepsis Watch November 5, 2018 July 5, 2019
NCT03960203 Completed N/A Effect of a Sepsis Prediction Algorithm on Clinical Outcomes January 2017 June 2018
NCT03996720 Completed Early Identification and Effective Management of Pediatric Sepsis October 1, 2018 September 30, 2021
NCT04227652 Completed N/A Control of Fever in Septic Patients September 3, 2013 March 31, 2019
NCT04291417 Completed Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&W November 20, 2019 June 17, 2020
NCT04353388 Completed Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington University February 3, 2020 July 17, 2020
NCT04804306 Completed Sepsis Post Market Clinical Utility Simple Endpoint Study - HUMC September 5, 2021 June 6, 2022
NCT04819035 Completed Sepsis Post Market Clinical Utility Simple Endpoint Study - Indiana University Hospital June 17, 2021 May 30, 2022
NCT04938531 Completed N/A Targeted Exercise Intervention to Reduce Morbidity and Mortality in Sepsis February 25, 2015 May 31, 2019
NCT05213923 Completed N/A ED Tracking Sheet Implementation July 1, 2021 June 1, 2022
NCT00463645 Completed Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients September 2005 January 2006
NCT00510835 Completed N/A Protocolized Care for Early Septic Shock March 2008 December 2013
NCT00534287 Completed Phase 3 Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock October 2007 June 2010
NCT00541827 Completed Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis October 2007 August 2012
NCT00568893 Completed Phase 4 An Open Label Study of Severe Sepsis in Adults January 2003 October 2003
NCT00135473 Completed Phase 3 Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) April 2003 September 2005
NCT00630656 Completed Phase 2 Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis April 2008 February 2010
NCT00634075 Completed Phase 4 Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis March 2008 August 2009
NCT00670254 Completed Phase 3 Hydrocortisone for Prevention of Septic Shock January 2009 August 2013
NCT00707122 Completed Phase 3 Volume Replacement With Albumin in Severe Sepsis July 2008 October 2013
NCT00709358 Completed Phase 4 Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections May 2008 September 2010
NCT00711620 Completed N/A Efficacy of Thymosin alpha1 for Severe Sepsis May 2008 January 2011
NCT00772096 Completed Phase 4 Septic Encephalopathy and Late Cognitive Dysfunction October 2008 June 2011
NCT00793442 Completed Endothelium in Severe Sepsis March 2008 May 2013
NCT00811629 Completed Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients January 2009 July 2009
NCT00819416 Completed Phase 2 Fluid Resuscitation in Early Septic Shock February 2009 February 2010
NCT00832039 Completed Phase 3 Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis November 2009 June 2013
NCT00835913 Completed Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact October 2008 September 2011
NCT00934011 Completed N/A Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections September 2009 May 2012
NCT00962156 Completed Phase 3 Scandinavian Starch for Severe Sepsis/Septic Shock Trial December 2009 March 2012
NCT00986271 Completed N/A Extravascular Lung Water Index in Severe Sepsis
NCT01049529 Completed Phase 2 Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients March 2007 September 2012
NCT01139489 Completed N/A Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) November 2009 August 2014
NCT01144624 Completed Phase 2 A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic Shock July 2010 August 2011
NCT01145560 Completed Phase 2 A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock October 2010 May 2012
NCT01223690 Completed Phase 3 Clarithromycin as Immunomodulator for the Management of Sepsis July 2007 April 2011
NCT01247792 Completed N/A End-of-life Decision-making in Patients With Sepsis-related Organ Failure August 2010 September 30, 2014
NCT01280942 Completed N/A Early Warning System for Clinical Deterioration on General Hospital Wards January 2011 May 2012
NCT01284452 Completed N/A Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) December 2010 March 2015
NCT01319630 Completed The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients April 2011 April 2016
NCT01329887 Completed Phase 3 The Effect of Ketanserin on the Microcirculation in Sepsis March 2011 May 2014
NCT01332734 Completed Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis March 2010 January 2011
NCT01337934 Completed Phase 3 Lactated Ringer Versus Albumin in Early Sepsis Therapy October 2013 December 2017
NCT01352182 Completed Phase 1/Phase 2 Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock October 2011 January 2017
NCT01378169 Completed SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU January 1, 2011 June 1, 2013
NCT01392508 Completed IMproved PREdiction of Severe Sepsis in the Emergency Department March 2011 September 2015
NCT01403935 Completed Sepsis Institutional Registry in Hospital Italiano de Buenos Aires December 2007 March 2014
NCT01449721 Completed N/A Preemptive Resuscitation for Eradication of Septic Shock September 2011 January 2016
NCT01474863 Completed Phase 2 Citrulline in Severe Sepsis August 2012 March 2016
NCT04955210 Not yet recruiting A Multi-Center Data System and Collaborative Network in China for Severe Infection and Sepsis Children May 30, 2024 December 31, 2025
NCT06143137 Recruiting Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up November 20, 2023 February 28, 2030
NCT05304728 Recruiting Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol February 15, 2021 December 31, 2024
NCT05895240 Recruiting Phase 4 Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality May 1, 2023 October 2023
NCT01315782 Recruiting Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis December 2016 December 2024
NCT02664753 Recruiting Phase 3 L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury March 5, 2018 May 2026
NCT05413343 Recruiting Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients January 1, 2022 January 1, 2025
NCT05048927 Recruiting Symphony IL-6 Cutoff Validation Study for Patients at Risk of Severe Sepsis August 31, 2021 December 31, 2024
NCT05665153 Recruiting Symphony IL-6 Study in Patients at Risk of Severe Sepsis November 22, 2022 November 21, 2024
NCT01273779 Suspended Phase 2/Phase 3 Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis June 2011 December 2014
NCT00484146 Terminated Alterations of Immunologic Mediators During Severe Sepsis June 2006 December 2012
NCT01903746 Terminated Epidemiology of Septic Shock in Medical or Polyvalent ICU in the North-East Region of France October 2010 January 2011
NCT01371929 Terminated Plasma Inducible Nitric Oxide Synthase (iNOS) Assay and Sepsis Study February 4, 2013 September 30, 2015
NCT02668432 Terminated Phase 4 Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic Shock May 2016 September 20, 2018
NCT01654003 Terminated N/A Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency Surgery April 2010 December 2014
NCT02424721 Terminated Sepsis Assessment in Belgian Emergency Rooms May 2015 December 2018
NCT01663779 Terminated N/A Comparison of Ultrasound-guided Versus Blind Insertion of Radial Artery Catheters August 2012 August 2014
NCT00167596 Terminated Phase 2/Phase 3 Near Infrared Spectroscopy (NIRS) in Severe Sepsis July 2005 December 2009
NCT02576457 Terminated Phase 1 Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe Sepsis December 2, 2015 March 15, 2017
NCT01957254 Terminated Investigate the Activity of Endotoxin in Severe Sepsis January 2013 December 2016
NCT01025180 Terminated Phase 4 Study of Procalcitonin (PCT)-Guided Antibiotic Use in Severe Sepsis Patients Without Obvious Infection December 2007 March 2010
NCT01449916 Terminated N/A Simplified Severe Sepsis Protocol in Zambia February 2012 November 2012
NCT00535821 Terminated Phase 4 Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock June 2007 September 2010
NCT00361725 Terminated Comparative Study of the Protein C Pathway in Septic and Non Septic Patients With Organ Failure March 2003 October 2003
NCT03334227 Terminated N/A High Flow Nasal Cannula in Severe Sepsis January 8, 2018 December 28, 2020
NCT01717651 Terminated Muscle Atrophy in Patients With Severe Sepsis December 2011 February 2013
NCT02109965 Terminated Phase 4 The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis July 2014 February 24, 2018
NCT01312675 Terminated N/A S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRT April 2011 June 2015
NCT01315496 Terminated Phase 3 GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock October 2009 December 2013
NCT01895647 Terminated N/A Effect of Different Electric Muscle Stimulation in Patients With Severe Sepsis and Respiratory Failure June 2013 September 2015
NCT02903082 Terminated Following of Myeloid-derived Suppressor Cells (MDSC) in Severe Sepsis: What Relationship With Systemic Inflammatory Syndrome? April 2015 January 2018
NCT03895853 Terminated Phase 2 Early Metabolic Resuscitation for Septic Shock October 4, 2019 May 4, 2020
NCT04178382 Unknown status N/A Effect of PCR-CRISPR/Cas12a on the Early Anti-infective Schemes in Patients With Open Air Pneumonia August 1, 2019 August 30, 2020
NCT00484133 Unknown status Phase 4 Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis June 2007
NCT01724463 Unknown status Electronic Application of a Severe Sepsis Screening Tool and Management Bundle March 2013 October 2018
NCT01797978 Unknown status Phase 3 Methylene Blue in Severe Sepsis and Septic Shock February 2013 March 2017
NCT01841190 Unknown status Prognostic Evaluation Of Severe Sepsis And Septic Shock. Procalcitonin Versus Delta Sofa May 2012
NCT01858909 Unknown status Phase 3 Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock May 2013 December 2013
NCT00791310 Unknown status Phase 3 Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology November 2008 October 2010
NCT00837057 Unknown status Phase 4 Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury February 2009
NCT00975793 Unknown status Phase 3 Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial October 2008 April 2015
NCT01992796 Unknown status Phase 3 Angiotensin II Antagonist in Severe Sepsis January 2014 January 2017
NCT03752489 Unknown status Phase 2 Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment April 1, 2022 March 31, 2024
NCT01211899 Unknown status 4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic Shock September 2010
NCT02871895 Unknown status Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis July 2013 December 2018
NCT02887274 Unknown status Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis July 2013 December 2018
NCT01249222 Unknown status N/A Pro-inflammatory Cytokines Profile and Mortality Rate of Critically Ill Septic Patients Following Plasmapheresis November 2008 February 2011
NCT02899143 Unknown status Phase 2 Short-course Antimicrobial Therapy in Sepsis September 2016 October 2021
NCT02135796 Unknown status Echocardiography in Septic Shock October 2008 December 2019
NCT02195830 Unknown status N/A Inferior Vena Cava Collapsibility Index in Severe Sepsis July 2014 July 2015
NCT02972827 Unknown status N/A Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock May 2015 May 2022
NCT01486524 Unknown status Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe Sepsis October 2011 April 2012
NCT01493466 Unknown status Serum Proteomics Analysis for Sepsis May 2010 March 2012
NCT00449800 Unknown status Phase 4 Pharmacokinetic of Ceftriaxone in Septic ICU Patients July 2006 March 2007
NCT05231720 Unknown status Mannheim Register of Sepsis and Septic Shock December 3, 2019 December 2023
NCT03115125 Unknown status N/A Descriptive Study of the Evolution in Proportion of Regulatory B Lymphocytes in Patients Hospitalized in Intensive Care for Severe Sepsis April 20, 2016 May 19, 2017
NCT01590303 Unknown status Phase 2 Outcome Following Vitamin C Administration in Sepsis May 2012 September 2013
NCT03141112 Unknown status The Benefits of Early Initiation of Continual Renal Replacement Therapy in Patients With Severe Sepsis August 2016 December 2020
NCT02258984 Unknown status N/A Can the Venus 1000 Help Clinicians Treat Patients With Severe Sepsis or Acute Heart Failure? The CVP Trial October 2014 December 2015
NCT01397474 Unknown status Phase 4 Peripheral Perfusion Targeted Fluid Management October 2011 January 2014
NCT00335907 Unknown status N/A Protocol-driven Hemodynamic Support for Patients With Septic Shock September 2006 January 2011
NCT04005001 Unknown status Phase 2 Machine Learning Sepsis Alert Notification Using Clinical Data September 25, 2021 August 31, 2022
NCT03882476 Withdrawn Phase 2 RCT of Sepsis Machine Learning Algorithm January 1, 2020 February 28, 2021
NCT02587078 Withdrawn Phase 4 Volume Therapy With Crystalloids and Colloids and Hemodynamic Monitoring in Patients With Severe Sepsis March 2013 June 2013
NCT01926301 Withdrawn Cerebrovascular Autoregulation in Sepsis, Influence of Renal Replacement Therapy August 2013 June 2020
NCT03644940 Withdrawn Phase 2 Subpopulation-Specific Sepsis Identification Using Machine Learning December 2020 July 2021
NCT01314066 Withdrawn Phase 2 Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS) July 2010 February 2016
NCT03734484 Withdrawn Phase 2 Gram Type Infection-Specific Sepsis Identification Using Machine Learning May 1, 2022 March 1, 2023
NCT02684487 Withdrawn Phase 3 Vitamin D Status in Patients With Severe Sepsis December 2017 December 2022
MedGen concept unique identifier (MedGen Concept name)
C1719672
MedGen unique identifier (MedGen Concept name)
318553