bacterial vaginosis
Information
- Disease name
- bacterial vaginosis
- Disease ID
- DOID:3385
- Description
- "A vaginitis that is characterized by a grayish vaginal discharge usually of foul odor and the presence of Gardnerella vaginalis." [url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bacterial+vaginosis]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06131749 | Active, not recruiting | Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa | March 1, 2021 | September 30, 2024 | |
| NCT05666778 | Active, not recruiting | Phase 2 | Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs | February 13, 2023 | July 31, 2027 |
| NCT06154239 | Active, not recruiting | N/A | Screening With Tampons: Evaluating Diagnostic Accuracy and HPV and Assessing Participant Views | January 15, 2024 | July 2024 |
| NCT04370548 | Completed | Phase 3 | DARE-BV1 in the Treatment of Bacterial Vaginosis (DARE-BVFREE) | June 16, 2020 | December 7, 2020 |
| NCT00140764 | Completed | Phase 3 | Intravaginal Treatment of Disturbances of Vaginal Flora Among HIV Infected and Uninfected Women in Malawi | January 2003 | March 2005 |
| NCT00229216 | Completed | Phase 3 | Treatment of Bacterial Vaginosis With Oral Tinidazole | January 2005 | June 2007 |
| NCT02147899 | Completed | Phase 2 | A Phase 2 Study of SYM-1219 to Treat Bacterial Vaginosis | May 2014 | October 2014 |
| NCT02150655 | Completed | Early Phase 1 | Study of the Microbiota, Metabolome, and Environmental Toxins in Relation to Reproductive Health in Rwandan Women | September 2012 | December 2013 |
| NCT02203942 | Completed | Comparing NAAT Testing to Standard Methods for the Diagnosis of Vaginitis | July 2014 | June 2015 | |
| NCT02210689 | Completed | Phase 3 | A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women | January 2014 | December 2014 |
| NCT02236156 | Completed | Phase 3 | Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV) | October 3, 2014 | October 4, 2016 |
| NCT02237950 | Completed | Phase 3 | Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV) | October 13, 2014 | February 22, 2017 |
| NCT02295579 | Completed | Will Lactobacillus Increase Cure Rate After Treatment of Bacterial Vaginosis and Chronic Vulvovaginal Candida | June 2014 | November 2015 | |
| NCT02348463 | Completed | Treatment of Bacterial Vaginosis in Early Pregnancy in Skaraborg and the Effect on Spontaneous Preterm Delivery | January 2007 | June 2014 | |
| NCT02418845 | Completed | Phase 3 | A Phase 3 Study of SYM-1219 Treatment of Women and Post-Menarchal Adolescent Girls With Bacterial Vaginosis | May 28, 2015 | December 5, 2015 |
| NCT02432404 | Completed | Phase 4 | Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity | March 2016 | November 2021 |
| NCT02445989 | Completed | Phase 4 | Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity | May 2016 | December 2018 |
| NCT02452866 | Completed | Phase 3 | Open-Label Study to Evaluate Safety of A Single Dose of SYM-1219 | June 2015 | October 2015 |
| NCT02459665 | Completed | N/A | Rwanda Vaginal Microbiota Restoration Study | June 5, 2015 | August 6, 2018 |
| NCT02527941 | Completed | Phase 1 | Effect of Bacterial Vaginosis on HIV Susceptibility and Female Genital Immunology | August 2015 | November 2015 |
| NCT02709005 | Completed | Phase 2 | Safety and Efficacy of 5% Monolaurin Vaginal Gel Administered Intravaginally for the Treatment of Bacterial Vaginosis | April 14, 2016 | December 11, 2017 |
| NCT02744638 | Completed | N/A | Effect of a Yoghurt Containing Four Probiotic Lactobacillus Strains on Bacterial Vaginosis | February 2015 | September 2016 |
| NCT02766023 | Completed | Phase 2 | LACTIN-V Study for Recurrent Bacterial Vaginosis | June 3, 2016 | February 11, 2019 |
| NCT02863536 | Completed | N/A | A Study of the New Medical Device Polybactum® | September 8, 2016 | September 21, 2018 |
| NCT02866227 | Completed | Phase 2 | TOL-463 Phase 2 Study for Vaginitis | July 15, 2016 | June 10, 2017 |
| NCT02905890 | Completed | Phase 4 | The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis | October 2, 2017 | December 20, 2019 |
| NCT03045809 | Completed | Women's Improvement of Sexual Health (WISH) Demonstration Project | July 5, 2016 | August 6, 2018 | |
| NCT03091777 | Completed | Phase 3 | Study Evaluating the Equivalence of GDC-229 and Metronidazole Vaginal Gel 0.75% in the Treatment of Bacterial Vaginosis | March 10, 2017 | March 27, 2018 |
| NCT03099408 | Completed | Phase 4 | Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosis | July 1, 2017 | December 30, 2020 |
| NCT03116789 | Completed | N/A | Analysis of Ameliorative Effects of Oral Probiotics on Bacterial Vaginosis | April 11, 2017 | December 31, 2019 |
| NCT03187457 | Completed | N/A | PreFem: "What Happens to the Vaginal Microbiota When a BV Infection is Treated With Metronidazole?" | September 4, 2017 | November 14, 2017 |
| NCT03303859 | Completed | Bacterial Vaginosis Carriage in Early Pregnancy and Preterm Delivery in Martinique, F.W.I | December 18, 2013 | June 23, 2017 | |
| NCT03601429 | Completed | N/A | Dietary Supplementation of Lactogyn in Women With Bacterial Vaginosis | January 1, 2018 | August 31, 2018 |
| NCT03734523 | Completed | Clinical Trial to Survey Results of Flourish Vaginal Care System for Recurrent Bacterial Vaginosis | July 1, 2021 | February 28, 2022 | |
| NCT03762083 | Completed | N/A | Clinical Performance of a Vaginal Pessary (pHyph) in Bacterial Vaginosis | January 7, 2019 | November 18, 2019 |
| NCT03839875 | Completed | Phase 4 | Evaluation of Efficacy and Safety of Gynomax® XL Ovule | April 3, 2019 | August 9, 2019 |
| NCT03894813 | Completed | Phase 4 | Probiotics as Adjuvant Treatment for Bacterial Vaginosis | March 26, 2019 | December 30, 2020 |
| NCT03930745 | Completed | Phase 2 | Suppression Of Bacterial Vaginosis (BV) [SUBVert] | September 9, 2019 | December 6, 2021 |
| NCT00070746 | Completed | Perinatal Infections in Pakistan | June 2003 | July 2005 | |
| NCT04638257 | Completed | Phase 1 | Role of Oral Lactobacilli on Vaginal Flora of Pregnant Women | January 2013 | March 2015 |
| NCT04640922 | Completed | N/A | Clinical Performance and Safety of the Gedea Pessary in Adult Women With Bacterial Vaginosis | January 27, 2020 | June 1, 2022 |
| NCT05022212 | Completed | Phase 2 | Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition | May 10, 2021 | March 31, 2023 |
| NCT05211921 | Completed | N/A | Single Arm Study of Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis | December 7, 2021 | May 11, 2022 |
| NCT05354050 | Completed | Phase 1 | Pharmacokinetic Study of DARE-BV1 | November 3, 2020 | December 2, 2020 |
| NCT05386147 | Completed | N/A | Flourish HEC to Prevent Recurrence of BV | December 22, 2021 | November 15, 2022 |
| NCT05652959 | Completed | Real-world Performance and Safety of Cerviron® in the Treatment of Vaginitis | May 20, 2021 | May 30, 2022 | |
| NCT05701722 | Completed | N/A | Effect of Flourish HEC Vaginal Care System on BV Recurrence and the Vaginal Microbiome | March 29, 2023 | February 15, 2024 |
| NCT06056947 | Completed | Phase 3 | Evaluation of Efficacy and Safety of Two New Formulations Compared to Gynomax® XL Ovule | July 20, 2020 | August 26, 2021 |
| NCT00313131 | Completed | Phase 3 | Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments | January 2004 | May 2005 |
| NCT00318253 | Completed | N/A | The Effects of Cranberry Juice on Bacterial Adhesion | March 2006 | August 2006 |
| NCT00324818 | Completed | Phase 4 | Treatment of Bacterial Vaginosis | July 2002 | May 2006 |
| NCT00334633 | Completed | Phase 4 | Treatment of Bacterial Vaginosis (BV) With Tinidazole | November 2004 | December 2009 |
| NCT00464542 | Completed | Phase 4 | Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study | December 2007 | March 2010 |
| NCT00510614 | Completed | Early Phase 1 | Tinidazole for Recurrent Bacterial Vaginosis: A Pilot Study | October 2007 | September 2009 |
| NCT00537576 | Completed | Phase 1 | Safety Study of Lactobacillus Administered Vaginally to Healthy Women | November 2007 | April 2008 |
| NCT00542074 | Completed | N/A | Bacterial Vaginosis; A Randomized Trial to Reduce Recurrence | June 2003 | August 2005 |
| NCT00545181 | Completed | N/A | Recurrent Bacterial Vaginosis and Vaginal Acidifying Gel Trial | September 2007 | July 2009 |
| NCT00556179 | Completed | Phase 4 | Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial Vaginosis | September 2007 | |
| NCT00635622 | Completed | Phase 2 | Safety and Efficacy Study of Lactobacillus Administered Vaginally in Women With Bacterial Vaginosis | April 2008 | January 2009 |
| NCT00667368 | Completed | Phase 3 | Bacterial Vaginosis Home Screening to Prevent STDs | July 28, 2008 | December 31, 2014 |
| NCT00682851 | Completed | A Validation Study of Genzyme Diagnostics OSOM Trichomonas Rapid Test and BVBlue Test | July 2008 | April 2009 | |
| NCT00720291 | Completed | N/A | Inflammation and Treatment of Bacterial Vaginosis Near Term | February 2006 | November 23, 2010 |
| NCT00752193 | Completed | N/A | Safety and Efficacy of a Vaginally Administered Probiotic Lactobacilli Delivery System. | October 2008 | December 2015 |
| NCT00799214 | Completed | Phase 2/Phase 3 | BASIC (Boric Acid, Alternate Solution for Intravaginal Colonization) Study | April 2014 | February 2016 |
| NCT00799500 | Completed | N/A | Bacterial Vaginosis in Pregnancy: Detection by Weekly Vaginal pH Testing | January 2007 | December 2010 |
| NCT00802386 | Completed | Bacterial Vaginosis Screening at IUD Insertion | January 2008 | May 2011 | |
| NCT01020396 | Completed | Phase 1/Phase 2 | Bioequivalence of Metronidazole Gel, 0.75% in the Treatment of Bacterial Vaginosis | January 2002 | March 2003 |
| NCT01125410 | Completed | Phase 3 | Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis | January 2007 | February 2009 |
| NCT01160796 | Completed | Phase 3 | Lcr35® for Bacterial Vaginosis Prevention | June 2010 | April 2012 |
| NCT01201057 | Completed | Phase 2 | Dose Ranging Study of SPL7013 Gel for Treatment of Bacterial Vaginosis (BV) | August 2010 | May 2011 |
| NCT01230814 | Completed | Phase 2 | Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women | April 2011 | August 2013 |
| NCT01245322 | Completed | Phase 4 | Treatment of Bacterial Vaginosis Combined With Human Lactobacilli | January 2007 | October 2014 |
| NCT01258556 | Completed | Phase 2/Phase 3 | The Impact of Probiotic Bacteria on the Efficacy of Anti-retroviral Therapy and Recurrence of Bacterial Vaginosis | June 2010 | |
| NCT01335373 | Completed | Observational Program Neo-Penotran® Forte | October 2010 | April 2015 | |
| NCT01347632 | Completed | N/A | Study of How Bacterial Vaginosis and Its Treatment Affects Cervical and Vaginal Tissue | April 2011 | December 2011 |
| NCT01450462 | Completed | N/A | Vitamin D and Sexual Health | September 2011 | January 2013 |
| NCT01471457 | Completed | Phase 2/Phase 3 | Trial of Trimosan Gel Effect on Pessary-associated Bacterial Vaginosis | September 2009 | September 2014 |
| NCT01577238 | Completed | Phase 3 | A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis | March 28, 2012 | July 20, 2012 |
| NCT01577537 | Completed | Phase 3 | A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis | April 17, 2012 | October 5, 2012 |
| NCT01621399 | Completed | Phase 3 | Safety and Efficacy Study to Treat Bacterial Vaginosis | May 2012 | December 2012 |
| NCT01800825 | Completed | Phase 4 | Clindamycin to Reduce Preterm Birth in a Low Resource Setting | July 2013 | April 2016 |
| NCT01993524 | Completed | N/A | Supplementation of Standard Antibiotic Therapy With Oral Probiotics for Bacterial Vaginosis | March 2009 | February 2012 |
| NCT02042287 | Completed | Phase 4 | Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis | June 2014 | March 19, 2020 |
| NCT02042352 | Completed | PNA FISH, PCR and Gram Staining for Detection of Bacterial Vaginosis - a Comparative Clinical Study in a Danish IVF Setting | January 2014 | February 2015 | |
| NCT05434104 | Not yet recruiting | N/A | The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study | October 2022 | June 2024 |
| NCT06450990 | Not yet recruiting | Phase 1/Phase 2 | Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product in Women With Acute Vaginal Infection | July 8, 2024 | February 26, 2026 |
| NCT05590195 | Not yet recruiting | Phase 3 | Effect of PreforPro® on Urinary and Vaginal Health | May 1, 2024 | June 1, 2025 |
| NCT06438575 | Not yet recruiting | N/A | Point of Care Diagnosis of Vaginal Infections | June 2024 | December 2025 |
| NCT06349122 | Not yet recruiting | Phase 4 | Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth | August 2024 | January 2028 |
| NCT05278130 | Recruiting | N/A | Serial Screening and Treatment of Bacterial Vaginosis Trial | October 20, 2022 | December 2027 |
| NCT06135974 | Recruiting | Early Phase 1 | Vaginal lIve Biotherapeutic RANdomized Trial | October 19, 2023 | September 2024 |
| NCT04771728 | Recruiting | Phase 4 | A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial Vaginosis | February 1, 2020 | December 1, 2024 |
| NCT06123299 | Recruiting | N/A | A Randomised, Partly-blinded Investigation to Evaluate the Clinical Performance and Safety of pHyph in Adult Women With Bacterial Vaginosis Compared With an Untreated Control Group | November 20, 2023 | December 2024 |
| NCT06458543 | Recruiting | Phase 4 | Optimization of Bacterial Vaginosis Treatment in Women of Reproductive Age | June 1, 2024 | June 1, 2026 |
| NCT04219605 | Recruiting | Evaluation of a Rapid Microscopic Diagnostic System for Different Vaginitis Conditions | December 1, 2020 | December 2023 | |
| NCT05753813 | Recruiting | Early Phase 1 | Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome | February 27, 2023 | June 30, 2023 |
| NCT01829204 | Recruiting | Prospective Data Bank Creation to Study Vaginal Conditions | April 2013 | December 2027 | |
| NCT05340790 | Recruiting | Phase 1 | First in Human Study in Healthy Volunteers of Antimicrobial Peptide PL-18 Vaginal Suppositories | August 1, 2022 | March 1, 2024 |
| NCT05796921 | Recruiting | N/A | Lacticaseibacillus Rhamnosus CA15 (DSM 33960) Strain as a New Driver in Restoring the Normal Vaginal Microbiota | January 2, 2023 | March 30, 2024 |
| NCT05587283 | Recruiting | Phase 1 | Safety, Tolerability, and Acceptability Study of Intravaginal Administration of LABTHERA-001 Capsules in Healthy Women | November 2, 2022 | May 2023 |
| NCT05963711 | Recruiting | N/A | The Genital Microbiome of Male Partners of Women With Recurrent BV Undergoing Vaginal Microbiome Transplantation | October 17, 2022 | June 2026 |
| NCT06263465 | Recruiting | N/A | Precision Vaginal Microbiome Transplantation in Women With Bacterial Vaginosis | March 18, 2024 | December 31, 2025 |
| NCT00207480 | Suspended | Phase 1 | Brief, Behavioral Intervention to Reduce Douching Among Adolescent and Young Women | October 2004 | |
| NCT02376972 | Terminated | Phase 2 | Efficacy and Safety Study of Rifaximin Vaginal Tablets in Bacterial Vaginosis | April 2015 | February 2016 |
| NCT00741845 | Terminated | Phase 3 | Prevention of Persistence of Bacterial Vaginosis | June 2008 | |
| NCT05788991 | Terminated | Phase 4 | Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial Vaginosis | July 26, 2021 | August 25, 2022 |
| NCT00303082 | Terminated | Phase 3 | Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity | January 2006 | August 2009 |
| NCT02946346 | Terminated | N/A | Kinetics and Ecology of Human Papillomavirus Genital Infections in Young Women | November 11, 2016 | September 29, 2020 |
| NCT01762670 | Terminated | Phase 1/Phase 2 | GoldenCareTM for the Treatment of Bacterial Vaginosis | February 2013 | December 2013 |
| NCT01089348 | Unknown status | Phase 2/Phase 3 | A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis | July 2010 | December 2010 |
| NCT01152528 | Unknown status | Phase 3 | Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery | July 2010 | June 2011 |
| NCT01841411 | Unknown status | Phase 4 | Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis | March 2013 | June 2013 |
| NCT03080740 | Unknown status | Phase 4 | The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet Treatment of Bacterial Vaginosis | July 2016 | December 2017 |
| NCT00889356 | Unknown status | Phase 3 | Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis | September 2009 | March 2010 |
| NCT03357666 | Unknown status | Phase 2 | Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis | March 22, 2016 | March 30, 2018 |
| NCT02186145 | Unknown status | Phase 3 | Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections | January 2016 | January 2017 |
| NCT02185456 | Unknown status | Early Phase 1 | Validation of a Novel Diagnostic, Prognostic Assay for Bacterial Vaginosis | September 2014 | March 2016 |
| NCT02173184 | Unknown status | Phase 3 | Safety and Efficacy Study of Gynevac Lactobacillus Vaccine in the Treatment of Bacterial Vaginosis | June 2014 | July 2015 |
| NCT05060029 | Unknown status | Phase 4 | A Pilot Study to Evaluate the Efficacy and Safety of Lactobacillus Species Suppositories on Vaginal Health and pH | January 3, 2022 | August 12, 2022 |
| NCT01421615 | Unknown status | Phase 1 | Effect of Different Courses of Lactobacilli Treatment on Bacterial Vaginosis and Pregnancy Outcomes | January 2011 | May 2012 |
| NCT00124878 | Unknown status | Phase 3 | Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community | August 2003 | September 2009 |
| NCT00536848 | Unknown status | Phase 2/Phase 3 | The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients | October 2007 | August 2008 |
| NCT01558388 | Unknown status | Phase 4 | Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancy | September 2009 | December 2012 |
| NCT00217308 | Withdrawn | Phase 1 | Effect of Probiotic Lactobacilli on Vaginal Flora of Pregnant Women at High Risk for Preterm Delivery | February 2005 | September 2007 |
| NCT00682721 | Withdrawn | N/A | Valacyclovir Suppression to Improve the Stability of Vaginal Flora Among HSV-2 Seropositive Women | February 2009 | September 2010 |
| NCT03769688 | Withdrawn | Phase 1 | Safety and Efficacy of Vaginal Microbiota Transplant (VMT) in Women With Bacterial Vaginosis (BV) | March 2022 | December 2023 |
- Disase is a (Disease Ontology)
- DOID:2170
- Cross Reference ID (Disease Ontology)
- MESH:D016585
- Cross Reference ID (Disease Ontology)
- NCI:C116973
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:237092002
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0085166
- MedGen concept unique identifier (MedGen Concept name)
- C0085166
- MedGen unique identifier (MedGen Concept name)
- 43118