Annotation Detail

Information
Associated Genes
IL10
Associated Variants
IL10 MUTATION
IL10 MUTATION
Associated Disease
cystic fibrosis
Source Database
DisGeNET
Description
Pro-inflammatory alleles of three cytokine genotypes, IL-8, IL-10 and IL-1β, appear to be associated with slightly more severe lung disease in patients with CF over a 13 year period.
Pubmed
24853301
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0161881613679591
Drugs