Cirrhosis

Search with Google Search with Bing
Information
Disease name
Cirrhosis
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06348004 Active, not recruiting The Association Between Albumin Administration and Short-term Rebleeding Risk in Cirrhosis Patients With Acute Variceal Hemorrhage and Stable Hemodynamics February 1, 2024 April 2024
NCT02968810 Active, not recruiting Phase 2 Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis June 21, 2017 December 31, 2024
NCT03278925 Active, not recruiting Phase 1 Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With Cirrhosis August 9, 2018 December 31, 2024
NCT02626312 Active, not recruiting Phase 1 Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function February 15, 2016 April 28, 2026
NCT02143401 Active, not recruiting Phase 1 Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors November 7, 2014 May 20, 2025
NCT04642391 Active, not recruiting Defining the Mechanisms Underlying Adrenal Insufficiency in Cirrhosis August 2, 2021 June 30, 2024
NCT03654053 Active, not recruiting Phase 3 Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis October 2, 2020 December 31, 2025
NCT03705078 Active, not recruiting N/A "Early TIPS" Versus Glue Obliteration to Prevent Rebleeding From Gastric Varices January 3, 2019 March 18, 2024
NCT04365868 Active, not recruiting Phase 2/Phase 3 Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis June 22, 2020 December 2024
NCT03059030 Active, not recruiting N/A Yttrium-90 Radioembolization for Cirrhosis-Associated Thrombocytopenia March 16, 2017 April 1, 2025
NCT02908048 Active, not recruiting Extracellular RNA Markers of Liver Disease and Cancer July 2014 July 2026
NCT05413083 Active, not recruiting Evaluation of Cardiac Function in Acutely Decompensated Cirrhosis June 6, 2022 October 31, 2024
NCT00124228 Completed Phase 3 Albumin Administration in Patients With Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis November 2004 October 2008
NCT00125762 Completed N/A FibroScan in Patients With Hepatitis B and C Presenting for Liver Biopsy March 2005 October 1, 2008
NCT00154492 Completed Phase 2 Use of NovoSeven® in Active Variceal Bleeding April 2004 August 2006
NCT00162552 Completed Phase 3 Clinical Trial of Pentoxifylline in Patient With Cirrhosis August 2004 December 2007
NCT06420791 Completed The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma：a Two-center Retrospective Cohort Study in China February 28, 2024 May 6, 2024
NCT00179413 Completed Phase 4 Study of Long-term Peg Intron vs. Colchicine in Non-responders. January 15, 2000 March 3, 2010
NCT00222014 Completed N/A TIPS With Coated Stents for Refractory Ascites in Patients With Cirrhosis May 2005 January 2013
NCT00244569 Completed Phase 3 Development of a Breath Test for Monitoring Patients With Liver Disease September 2005 April 2007
NCT00250315 Completed DOCICAR: Cardiac Dysfunction in Cirrhosis November 2005 October 2007
NCT00252642 Completed N/A Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C November 2005 September 2007
NCT00275652 Completed Phase 3 A Comparison of the Drug Telbivudine (LdT) and Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis. June 2004 August 2007
NCT00305591 Completed N/A Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment. March 2006 October 2007
NCT00312078 Completed N/A Effect of Yogurt on Minimal Hepatic Encephalopathy November 2005 April 2007
NCT00347009 Completed Phase 4 Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis May 2005 September 2009
NCT00359853 Completed Phase 4 Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis September 2000 March 2005
NCT00368225 Completed Transplant-Related Accelerated Progression of Hepatitis C June 22, 2006 January 22, 2009
NCT00420134 Completed Phase 1/Phase 2 Improvement of Liver Function in Liver Cirrhosis Patients After Autologous Mesenchymal Stem Cell Injection:a Phase I-II Clinical Trial February 2006 June 2009
NCT00424957 Completed Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System November 2006 October 2008
NCT00450164 Completed Phase 4 Secondary Prophylaxis After Variceal Bleeding in Non-Responders November 2000 June 2004
NCT00466336 Completed Prediction of Hepatic Fibrosis in Patients With Chronic Hepatitis C by Biochemical and Duplex Doppler Indices January 2003 January 2007
NCT00476060 Completed Phase 2 Mesenchymal Stem Cell Transplantation in Decompensated Cirrhosis January 2007 August 2011
NCT00479336 Completed Phase 2 A Dose-defining Study of OPC-41061 in Treatment of Hepatic Edema June 2007 January 2009
NCT00493480 Completed Phase 3 Danish Carvedilol Study in Portal Hypertension September 2003 August 2009
NCT00502086 Completed Phase 3 Efficacy and Safety of Viusid in Patients With Hepatic Cirrhosis Secondary to Hepatitis C Virus Infection. May 2005 July 2009
NCT00513201 Completed Phase 4 Lyspro Insulin vs Regular Insulin in Cirrhotic Patients
NCT00517738 Completed Phase 2 Effect of Physical Training Program on Health-related Quality of Life in Cirrhosis February 2007 May 2014
NCT00534677 Completed Phase 4 The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed May 2004 July 2005
NCT00570622 Completed Phase 4 Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosis December 2004 November 2008
NCT00570973 Completed Phase 4 Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy November 2004 May 2011
NCT00594191 Completed Phase 2 Efficacy and Safety of Simvastatin in the Treatment of Portal Hypertension March 2004 November 2007
NCT00596414 Completed Phase 4 Sedation and Analgesia for Transjugular Liver Biopsy: A Randomized Double Blind Placebo Controlled Trial May 2003 October 2005
NCT00629421 Completed Early Screening of Hepatocellular Carcinoma in Cirrhotic Patients: a Prospective Study January 1, 2001 December 31, 2016
NCT00701792 Completed N/A Liver Transplantation Versus Alternative Therapies for Patients With Pugh B Alcoholic Cirrhosis March 1994 November 2006
NCT00713934 Completed Phase 1/Phase 2 Autologous Bone Marrow Stem Cells in Cirrhosis Patients January 2008 February 2009
NCT00741663 Completed Phase 4 Spironolactone Versus Spironolactone Plus Furosemide (SVSSF) April 2005 September 2008
NCT05835180 Completed Phase 1 A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function May 1, 2023 December 18, 2023
NCT05724485 Completed Phase 4 Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis April 1, 2023 December 31, 2023
NCT05689268 Completed N/A EUS-PPG vs HVPG in Portal Hypertension February 1, 2023 September 20, 2023
NCT00764049 Completed Phase 1/Phase 2 Single Pass Albumin Dialysis in Patients With Cirrhosis June 2009 July 2012
NCT00772057 Completed N/A Beta-blockers for Prevention Of Growth Of Small Esophageal Varices In Cirrhosis: An Randomized Controlled Trial (RCT) October 2004 October 2008
NCT00802555 Completed Phase 1 Safety Study of ARQ 197 in Cirrhotic Patients With Hepatocellular Carcinoma (HCC) January 2009 December 2011
NCT00820781 Completed N/A Endoscopic Sclerotherapy and/or Ligation Versus Portacaval Shunt for Bleeding Gastric Varices August 1977 April 2003
NCT00883454 Completed Estimation of Functional Liver Reserve Using Cholinesterases
NCT00888784 Completed N/A Secondary Prophylaxis Gastric Variceal Bleed August 2006 January 2009
NCT00905996 Completed N/A Primary Prophylaxis of Gastric Varix Bleed August 2006 January 2009
NCT05545670 Completed Phase 2/Phase 3 Allopurinol to Prevent Cirrhosis Related Morbidities June 15, 2022 March 1, 2023
NCT00921349 Completed Phase 4 A Trial of Ligation Plus Nadolol Versus Nadolol Alone in the Prophylaxis of First Variceal Bleeding in Cirrhosis December 2004 May 2009
NCT00926224 Completed N/A Fibroscan® and Its Dedicated Probes Efficiency in Obese Patients July 2009 September 2010
NCT02400216 Completed Deciphering the Mechanisms Involved in Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis May 29, 2015 April 25, 2017
NCT03137719 Completed Infections in Hospitalized Cirrhotic Patients January 1, 2011 February 26, 2020
NCT03144713 Completed N/A Efficacy and Safety of Terlipressin With Albumin Versus Midodrine With Albumin Versus Albumin Alone in Prevention of Paracentesis Induced Circulatory Dysfunction in Cirrhosis May 28, 2017 April 30, 2018
NCT00043303 Completed Phase 2 Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis September 2001 November 2003
NCT00048724 Completed Phase 3 Peg-Intron for Prevention of Disease Progress in Chronic Hepatitis C Patients With Cirrhosis (Study P02569) June 2002 April 2008
NCT00058890 Completed Phase 3 Gabapentin to Treat Itch in Patients With Liver Disease November 2000 January 2004
NCT00059267 Completed Prevention of Recurrent Hepatitis B After Liver Transplantation March 2001 November 2007
NCT00076336 Completed Phase 3 Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis December 2003
NCT00096733 Completed Adult-to-Adult Living Donor Liver Transplantation Study October 2004 August 2010
NCT00108355 Completed Phase 4 Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis December 2003 August 2012
NCT00115947 Completed Phase 2/Phase 3 Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites December 2004 January 2006
NCT00122135 Completed N/A A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making December 2004 September 2009
NCT03416751 Completed Phase 1 Fecal Microbial Transplant for Alcohol Misuse in Cirrhosis February 1, 2018 April 10, 2020
NCT02854371 Completed Phase 4 Evaluation of Hepatic Function Using Gadoxetic Acid Enhanced MRI August 2016 May 2018
NCT02907749 Completed Phase 4 Spironolactone on Fibrosis Progrssion-Portal Hypertension(FP-PH)in Cirrhosis January 1, 2018 July 31, 2020
NCT03407001 Completed Early Phase 1 Contrast Enhanced Ultrasound With Lumason in Detecting Liver Cancer in Participants With Cirrhosis January 12, 2018 September 15, 2020
NCT03396796 Completed N/A Modified Vagus Nerve-preserving Laparoscopic Splenectomy and Azygoportal Disconnection April 9, 2018 December 31, 2019
NCT03368066 Completed Phase 3 Is Adrenal Insufficiency Under-diagnosed in Hospitalized Cirrhosis Patients? January 29, 2018 March 12, 2019
NCT02944643 Completed N/A Mindfulness and Support Group to Improve Patient and Caregiver Burden in Cirrhosis June 2016 January 2017
NCT02960204 Completed Phase 2 Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension October 17, 2016 April 8, 2019
NCT03339232 Completed N/A BCAA Supplemental Study October 2, 2017 June 17, 2019
NCT03293459 Completed N/A Influence of Shunt Occlusion on Organ Functions in Hyperammonemic Patients With Cirrhosis Having Porto-systemic Shunt. July 3, 2017 July 31, 2019
NCT02991612 Completed N/A Rifaximin in Patients With Gastroesophageal Variceal Bleeding November 25, 2016 February 28, 2018
NCT03285217 Completed N/A HMB for Denutrition in Patients With Cirrhosis (HEPATIC) October 15, 2017 December 31, 2019
NCT00004796 Completed Phase 2 Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis November 1994 February 1997
NCT03246048 Completed Long Term Follow-up of Hepatitis C Cured Patients January 2016 June 2021
NCT03030820 Completed N/A Oral Gut Liver Axis in Cirrhosis October 2016 March 2018
NCT03242798 Completed Assessment of Nutritional Status of Patients With Liver Cirrhosis March 3, 2016 March 2020
NCT03069131 Completed Phase 3 Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites March 20, 2018 March 20, 2023
NCT03176966 Completed Phase 4 Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis September 2, 2016 October 22, 2021
NCT03071458 Completed Mutational Landscape in Hepatocellular Carcinoma January 2008 May 2015
NCT03154476 Completed Phase 3 Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study July 5, 2017 June 30, 2019
NCT03091738 Completed Phase 4 Ramelteon for Treatment of Insomnia in Cirrhosis February 1, 2017 October 1, 2018
NCT03107091 Completed Phase 2 Continuous Infusion Terlipressin for Patients With Cirrhosis and Refractory Ascites July 15, 2017 April 25, 2019
NCT00968695 Completed Phase 4 Effects of Long Term Albumin 20% Administration in Patients With Cirrhosis and Ascites. July 2009 April 2014
NCT00986817 Completed Phase 3 Terlipressin in Cirrhotic Patients With Recidivation Ascites Treated With Paracentesis and Albumin November 2009 April 2015
NCT00999167 Completed Phase 2 A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy December 2009 April 2012
NCT01048788 Completed Phase 3 A Trial of OPC-41061 in Patients With Hepatic Edema - Investigation of the Safety of Treatment at 7.5 mg Beyond 7 Days and of the Effect of Dose Escalation to 15 mg December 2009 August 2011
NCT01050530 Completed Phase 3 A Trial to Investigate the Efficacy of OPC-41061 Administered at a Dose of 7.5 mg in Patients With Hepatic Edema December 2009 February 2012
NCT01060813 Completed N/A Study of the Benefit of Exercise and Aminoacid Supplements in Cirrhotic Patients January 2010 December 2010
NCT01072721 Completed N/A Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis January 19, 2010 April 30, 2018
NCT01080144 Completed N/A Feasibility of Critical Flicker Frequency Procedure for the Diagnosis of Minimal Encephalopathy October 2009 December 2012
NCT01095185 Completed Phase 3 Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding November 2010 September 2013
NCT01114828 Completed Phase 3 A Study to Investigate Pharmacodynamics and Pharmacokinetics of OPC-41061 in Patients With Hepatic Edema February 2010 December 2011
NCT01133795 Completed Phase 2 Midodrine and Albumin for Cirrhotic Patients With Functional Renal Impairment February 2010 June 2016
NCT05376488 Completed N/A Effect of Brief Dietary Intervention on Ammonia Levels May 1, 2022 April 20, 2023
NCT01141036 Completed N/A Propofol Versus Midazolam for Upper Endoscopy in Cirrhotic Patients July 2008 February 2009
NCT01157845 Completed Phase 3 Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis March 2010 July 2012
NCT01164332 Completed Phase 1 Sensitivity of Alternative NRL972 Detection Methods in Healthy Subjects July 2010 November 2011
NCT01165073 Completed N/A Short Term Feeding for Asian Patients With Liver Cirrhosis March 2008 May 2010
NCT01188733 Completed Phase 1/Phase 2 Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosis June 1998 December 2000
NCT01192698 Completed N/A Intravenous Interferon During Liver Transplant October 2009 February 2013
NCT01196481 Completed N/A Carvedilol + VSL#3 Versus Endoscopic Variceal Ligation for Primary Prophylaxis of Esophageal Variceal Bleeding in Cirrhotic Patients Non Responder to Carvedilol. December 2012 August 2015
NCT01196507 Completed N/A Early Primary Prophylaxis of Esophageal Varices November 2010 April 2014
NCT01208311 Completed Acoustic Liver Biopsy in Normals and in Patients With Cirrhosis Using Endoscopic Ultrasound December 2004 December 2016
NCT05309200 Completed Phase 2 A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury April 28, 2022 October 13, 2023
NCT01217983 Completed Utility of Renal Biomarkers in Cirrhosis October 2010 October 2012
NCT01231828 Completed N/A Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies. September 2009 December 2012
NCT01242280 Completed Phase 3 Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding. January 2010 June 2014
NCT01267669 Completed N/A A Trial of Somatostatin With Endoscopic Variceal Ligation (EVL) in Control of Acute Variceal Bleeding November 2005 November 2009
NCT01283152 Completed N/A Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy. January 2011 June 2012
NCT01292304 Completed Phase 4 Tolvaptan for Ascites in Cirrhotic Patients March 2012 January 2015
NCT01300390 Completed Assessment of Endothelial Function, Apolipoproteins and Adiponectin June 2011 October 2015
NCT05304455 Completed N/A Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection April 1, 2022 May 31, 2023
NCT05300516 Completed N/A Vagus Nerve-guided Robotic-assisted Splenectomy and Azygoportal Disconnection April 1, 2022 July 31, 2023
NCT05231772 Completed N/A Probiotics and Hemodynamic Changes in Cirrhosis March 1, 2021 March 29, 2022
NCT05170854 Completed The Impact of Liver Cirrhosis on Outcomes in Trauma Patients October 16, 2018 September 4, 2020
NCT01362855 Completed Advance Care Planning Evaluation in Hospitalized Elderly Patients September 2011 May 2015
NCT01387061 Completed N/A Resection for Multiple Hepatocellular Carcinomas (HCC) June 2001 June 2011
NCT01387503 Completed N/A Expansion of Conventional Criteria for Liver Transplantation in Hepatocellular Carcinoma Through Downstaging January 2011 July 31, 2019
NCT01403987 Completed N/A Improving Performance of Paracentesis in Medical Residency Training January 2011 March 2012
NCT01408966 Completed Phase 2 Effects of Dark vs. White Chocolate on the Postprandial Increase in Portal Pressure in Cirrhosis August 2008 June 2009
NCT01434108 Completed Phase 2/Phase 3 Effects of the Administration of Ornithine Phenylacetate in Patients With Cirrhosis and Upper Gastrointestinal Bleeding October 2011 March 2015
NCT01447537 Completed N/A Mechanisms Involved in the Benefits of an Exercise Programme in Patients With Cirrhosis September 2011 June 2012
NCT01458990 Completed N/A Proton Pump Inhibitors and Dysbiosis in Cirrhosis October 2011 February 2018
NCT01463735 Completed Phase 2 Vitamin E Supplement in Patients With Cirrhosis and Acanthocytosis November 2011 May 2013
NCT01476995 Completed Prognostic Indicators as Provided by the EPIC ClearView September 2010 June 2011
NCT05061992 Completed Phase 2/Phase 3 A Trial to Improve Quality of Life in People With Cirrhosis November 10, 2021 November 1, 2022
NCT05013502 Completed Phase 1 Empagliflozin in Diuretic Refractory Ascites November 15, 2021 June 30, 2023
NCT01542749 Completed Total Body Albumin Measurement Utilizing a Modification of the BVA 100 Blood Volume Analyzer January 2009 January 2012
NCT01551966 Completed N/A Esophageal Capsule Endoscopy in Children October 2011 July 2013
NCT01556646 Completed Phase 3 Effect of Tolvaptan on Cognitive Function in Cirrhosis April 2011 June 2013
NCT01562821 Completed Phase 2 Safety and Efficacy of Activated Recombinant Human Factor VII in Cirrhotic Patients Undergoing Partial Hepatectomy July 2001 December 2002
NCT01578226 Completed Procalcitonin in Cirrhotic Patients at High Risk for Sepsis October 2009 September 2011
NCT01603953 Completed Bioelectrical Impedance Vector Analysis in Cirrhotic Patients January 2009 May 2014
NCT04994548 Completed Endoscopic Resection of Early Esophageal Tumors in the Context of Cirrhosis or Portal Hypertension January 1, 2005 March 31, 2021
NCT01655121 Completed N/A Effect of High-protein High-fiber Diet in Patients With Autoimmune Hepatitis January 2012 July 2014
NCT01657695 Completed Hepatocellular Carcinoma Growth and Molecular Aggressiveness June 2008 August 2012
NCT04976543 Completed Phase 4 Safety of Anticoagulant Therapy After Endoscopic Treatment February 1, 2020 June 28, 2022
NCT01676285 Completed Phase 3 Metoprolol Succinate in Cardiac Remodeling Related to Cirrhosis January 2012 March 2014
NCT01686698 Completed Phase 4 Effect of VSL#3 (Original De Simone Formulation) on Cognitive Function, Risk of Falls and Quality of Life in Patients With Cirrhosis March 2013 March 2016
NCT01687257 Completed Phase 2 Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation July 2012 October 2015
NCT01713478 Completed N/A Subclinical Myocardial Dysfunction in Patients With Hepatic Cirrhosis December 2011 December 2014
NCT01761851 Completed Resting Energy Expenditure in Patients on the Waiting List for Liver Transplantation March 2010 December 2011
NCT01774617 Completed Comparative Analysis of Different Tests to Evaluate Prognosis of Patients on Liver Transplant Waiting List December 2015 November 2018
NCT04939350 Completed Evaluation of the Vaccination Coverage of Cirrhotic Patients Followed in the General Hospitals in France in 2021 September 27, 2021 December 27, 2022
NCT01799785 Completed N/A Effects of Aerobic Training on Exercise Capacity in Patients With Cirrhosis February 2013 July 2013
NCT04899115 Completed Phase 2 VE303 for Treatment of Hepatic Encephalopathy (HE) August 6, 2021 August 30, 2023
NCT04788173 Completed Assessment Of Lipid Profile In Cirrhotic Patients March 1, 2021 September 1, 2021
NCT01842581 Completed Phase 4 The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy January 8, 2013 December 17, 2014
NCT04675775 Completed N/A The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy. January 21, 2021 March 5, 2023
NCT01847651 Completed Phase 4 Brain Muscle Axis During Treatment of Hepatic Encephalopathy With L-ornithine L-aspartate August 2013 June 2015
NCT01851252 Completed Phase 1 MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy October 2013 August 2017
NCT04650295 Completed N/A Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles Trial January 18, 2021 December 2, 2021
NCT01872767 Completed Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure June 2013 November 2014
NCT04645550 Completed Phase 4 Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy（ESAWAAPT） November 22, 2020 March 31, 2023
NCT01884415 Completed Phase 3 Phase III, Study to Evaluate the Efficacy of Two Different HBV Vaccination Schemes in Patients With Hepatic Cirrhosis September 7, 2012 December 2017
NCT01888900 Completed Phase 2 New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C May 2013 November 2015
NCT01893541 Completed Phase 4 PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES? June 2008 June 2011
NCT01944878 Completed The Association With Peptic Ulcer Disease and Hepatic Vein Pressure Gradient May 2013 August 2013
NCT04248816 Completed N/A Hepatocellular Carcinoma Surveillance in Cirrhotics November 19, 2020 February 14, 2022
NCT04244487 Completed N/A Laparoscopic Splenectomy and Azygoportal Disconnection With Intraoperative Endoscopic Variceal Ligation January 3, 2020 December 31, 2021
NCT01960127 Completed N/A Effects of Aerobic Training on Exercise Capacity in Patients With Advanced Cirrhosis 2 October 15, 2013 May 31, 2017
NCT04155515 Completed Phase 3 A Phase III Study to Evaluate Efficacy and Safety of TG-2349 in Combination With DAG181 and RBV for HCV Type I Patients June 13, 2019 August 11, 2020
NCT04153604 Completed Doxycycline for the Prevention of Spontaneous Bacterial Peritonitis November 4, 2019 August 7, 2020
NCT02009748 Completed Phase 2 Vitamin D Supplementation in Cirrhotic Patients December 2013 June 2015
NCT02016196 Completed Phase 3 Rifaximin vs Placebo for the Prevention of Encephalopathy in Patients Treated by TIPS September 2013 July 2017
NCT02017119 Completed Phase 2 Comparison Between Lactulose and Lactulose-Paraffin in Cirrhotic Patients January 2011 June 2014
NCT02056041 Completed Selection Criteria for Safe Hepatectomy for Hepatocellular Carcinoma January 2004
NCT03987048 Completed Cirrhotic Patients With Septic Shock April 2014 April 2015
NCT02083367 Completed Default Mode Network fMRI Maps as a Predictive Index of Hepatic Encephalopathy Outcome January 2013 February 2015
NCT02085915 Completed N/A Evaluation of the Strip PeriScreen for the Fast Diagnosis of the Spontaneous Infection of the Liquid of Ascites During the Cirrhosis March 2014 September 2015
NCT02097784 Completed N/A Interest of the Echocardiography in the Management of Cirrhotic Patients With Acute Kidney Injury March 2014 July 2018
NCT02113631 Completed N/A Comparative Effectiveness and Tolerability of Boceprevir vs Telaprevir September 2011 April 2013
NCT03965260 Completed Data Collection and Identification of Infection-responsible Bacterial Resistances in Cirrhotic Patients November 1, 2018 March 31, 2020
NCT02132351 Completed Hepatic Fibrosis Non-invasive Methods Questionnaire August 2013 April 2016
NCT02132962 Completed N/A Sarcopenia and Cirrhosis May 2014
NCT02151864 Completed Phase 1 LDE225 in Patients With Advanced or Metastatic Hepatocellular Carcinoma and Child-Pugh A/B7 Cirrhosis July 2014 September 2017
NCT02154282 Completed N/A iPod Games in Hepatic Encephalopathy January 2013 July 2016
NCT02173288 Completed Phase 2/Phase 3 Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites July 2013 March 2016
NCT02180113 Completed N/A Spleen Stiffness Measurement With FibroScan March 2012 June 2017
NCT03948659 Completed Ventriculo-arterial Coupling in Cirrhotics August 30, 2018 April 30, 2019
NCT03932552 Completed N/A Effects of a Novel Physical Exercise Program in Patients With Cirrhosis (the LFN-exercise Protocol) February 1, 2016 January 31, 2020
NCT02247414 Completed Phase 4 Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection September 2014 April 2018
NCT02249741 Completed Phase 4 Prospective Study of Profile of Hepatic Osteodystrophy in Patients With Non-Choleastatic Liver Cirrhosis and Impact of Bisphosphonate Supplementation August 2012 February 2014
NCT03919032 Completed Bacterial Infections in Patients With Cirrhosis in Argentina: Clinical and Microbiological Characteristics October 16, 2018 December 31, 2019
NCT03846843 Completed Phase 1 OCR002-SP103 - Oral Immediate Release Study August 15, 2016 December 31, 2017
NCT02267421 Completed N/A Effects of Home Based Exercise Therapy in Early Cirrhosis October 2014 December 2015
NCT03837444 Completed Microvesicles and Monocytes to Predict Mortality of Patients With Cirrhosis June 12, 2019 February 29, 2024
NCT03796598 Completed Phase 1/Phase 2 FMT in Cirrhosis and Hepatic Encephalopathy July 29, 2019 December 20, 2023
NCT02273362 Completed Phase 1/Phase 2 Erlotinib Hydrochloride in Preventing Liver Cancer in Patients With Cirrhosis of the Liver November 24, 2014 March 10, 2022
NCT03706846 Completed N/A Study of Two Fasting Procedures Before Gastroscopy: 6 Hours Versus 2 Hours for Clear Fluids April 18, 2018 August 27, 2018
NCT02298868 Completed Phase 2 Safety and Efficacy of Baclofen for Treatment of Muscle Spasms in Patients With Cirrhosis: A Pilot Study October 2012 November 2014
NCT02304159 Completed Phase 4 Study to Evaluate the Safety and Efficacy of Daclatasvir/Sofosbuvir/Ribavirin for 16 Versus 24 Weeks for HCV Genotype 3 Cirrhotics January 2015 August 2017
NCT02310165 Completed N/A Insertion Technique in Large Volume Paracentesis July 2013 June 2014
NCT02321202 Completed Phase 4 Omega-3 Fatty Acid-Based Parenteral Nutrition Improves Postoperative Recovery for Cirrhotic Patients With Liver Cancer March 2010 November 2013
NCT02344719 Completed Phase 4 Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis October 2010 June 2015
NCT03599492 Completed The Effect of Transjugular Intraheptic Portosystemic Shunt (TIPS) on Gastrointestinal Motility and the Gut Microbiota November 2016 April 12, 2022
NCT03593447 Completed Phase 2 To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients March 15, 2018 February 17, 2020
NCT02372682 Completed Shear Wave Sonoelastography in Pediatric Liver Fibrosis May 11, 2015 May 31, 2018
NCT02389127 Completed Relationship Between HbA1c and Chronic Glycemia in Patients With Cirrhosis July 2015 June 1, 2017
NCT02400164 Completed N/A A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites March 2015 March 31, 2018
NCT03145168 Completed N/A High Versus Low Target Mean Arterial Pressure in Septic Shock in Critically Ill Cirrhotics September 19, 2018 March 18, 2021
NCT03585257 Completed Phase 2 HEAL STUDY (Hepatic Encephalopathy and Albumin Study) June 20, 2018 March 30, 2022
NCT03566914 Completed N/A Tadalafil for Erectile Dysfunction in Patients With Cirrhosis June 30, 2018 December 28, 2019
NCT02439567 Completed N/A Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C) January 2015 September 2016
NCT02442284 Completed Phase 3 A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in US Veterans With Genotype 1 Chronic Hepatitis C Virus Infection May 13, 2015 October 31, 2016
NCT02451033 Completed Phase 2/Phase 3 Granulocyte Colony Stimulating Factor And Growth Hormone In Cirrhosis Of Liver: An Open Label Study May 2015 June 2016
NCT02457403 Completed N/A Comparison of Blood Product Use and Bleeding Events During and After Endoscopic or Neurosurgical Procedures in Patients With Cirrhosis and Coagulopathy May 2015 November 30, 2018
NCT03564626 Completed N/A Health IT Generated PROs to Improve Outcomes in Cirrhosis June 22, 2018 May 22, 2024
NCT03513900 Completed Non-invasive Methods to Predict PHG in Cirrhosis March 6, 2018 April 20, 2019
NCT02475122 Completed N/A Prognostic Value of Measuring DsAz by MRI in Cirrhotic Patients on Prophylactic Treatment With β Blocker (AzyMR) October 2014 December 2020
NCT03513887 Completed Noninvasive Tests to Predict the Presence of Esophageal Varices in Patients With Liver Cirrhosis February 28, 2018 January 12, 2019
NCT02480972 Completed N/A Hepatic Fibrosis Assessment Using Multiparametric Magnetic Resonance Imaging June 23, 2015 August 28, 2020
NCT02484534 Completed Thrombin Generation Test in Patient With Liver Cirrhosis February 26, 2015 January 18, 2017
NCT02484963 Completed N/A The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia May 15, 2015 January 15, 2017
NCT02508298 Completed N/A Surrogate Markers of Portal Pressure April 2014 July 2019
NCT02528760 Completed N/A To Determine the Role of Prokinetics in Feed Intolerance in Critically Ill Cirrhosis September 24, 2015 August 31, 2017
NCT02533934 Completed Phase 4 Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant August 2016 December 31, 2019
NCT02534805 Completed Patient Buddy App for the Prevention of Avoidable Readmission in Cirrhosis August 2015 January 2017
NCT02540382 Completed N/A Comparison of Covered and Bare Stent in TIPS January 2006 December 2014
NCT02596880 Completed Phase 3 Sofosbuvir, Daclatasvir, Ribavirin for Hepatitis C Virus (HCV) Cirrhotics September 2015 June 2016
NCT02628717 Completed Interferon/Ribavirin-Free Sofosbuvir Based Treatment (AURIC) July 2013 September 2017
NCT02636647 Completed Phase 1 Fecal Transplant in Recurrent Hepatic Encephalopathy October 2015 August 2016
NCT03507140 Completed Microbiota Study in Liver Transplanted Patients April 16, 2019 March 27, 2024
NCT02642003 Completed Phase 3 To Assess the Efficacy of Granulocyte Colony Stimulating Factor Versus Standard Medical Therapy in Patients of Decompensated Cirrhosis June 2014 February 2016
NCT03493204 Completed N/A Tackling 30-day Readmissions in Patients With Cirrhosis: The SALTYFOOD Trial April 24, 2018 August 19, 2019
NCT02650245 Completed N/A Breath and Blood Ammonia Response to an Oral Protein Challenge October 2015 April 2016
NCT02673411 Completed Ultrasonography SWE for Hepatic Fibrosis Evaluation March 3, 2016 January 16, 2017
NCT03483272 Completed MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI) January 8, 2018 April 21, 2021
NCT02705534 Completed Phase 3 Sofosbuvir, Ledipasvir, Ribavirin for Hepatitis C Cirrhotics, Genotype 1 September 2016 October 2017
NCT02737345 Completed Correlation of Hepatitis C, Alcoholic Liver Disease, and Renal Failure With Hyperfibrinolysis in Liver Failure November 1, 2015 April 1, 2017
NCT03458845 Completed Prevalence of Sarcopenia and Undernutrition in Patients With Cirrhosis and Abdominal Hernia May 30, 2018 April 20, 2021
NCT02756741 Completed N/A Comparison of Standard Dose Versus Once a Day Intravenous Albumin in Spontaneous Bacterial Peritonitis April 2014 July 2015
NCT03443934 Completed Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment April 1, 2017 April 21, 2021
NCT02758509 Completed Impact of Antiviral Therapy on Gastroesophageal Varices. January 1, 2010 October 15, 2017
NCT02774161 Completed N/A B-mode Ultrasound Imaging in Detecting Early Liver Cancer May 2016 June 19, 2017
NCT02776553 Completed N/A A Physical Activity Program in End-state Liver Disease June 2016 June 2020
NCT02821377 Completed Phase 2 Metabolic Effects of Furosemide +HSS in Refractory Ascites December 2013 April 2016
NCT03439189 Completed Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14 August 28, 2016 May 13, 2019
NCT02835365 Completed Observational Study on Patients With Baclofen Treatment for Alcohol-dependence in France January 1, 2015 September 2018
NCT03438916 Completed MRI to Assess the Effect of Non-selective Beta-blocker in Patients With Cirrhosis April 1, 2017 December 8, 2020
NCT06061328 Enrolling by invitation N/A Project OASIS: Optimizing Approaches to Select Implementation Strategies February 1, 2024 October 31, 2027
NCT03176797 Enrolling by invitation N/A Quantitative Diagnosis of Liver Fibrosis on Multiparametric MRI May 3, 2017 December 31, 2025
NCT05467826 Not yet recruiting Phase 4 Efficacy and Safety of SOF/VEL + RBV and SOF/VEL/VOX for 12 Weeks in HCV Subjects With GT3b and Compensated Cirrhosis September 1, 2022 December 31, 2023
NCT06345547 Not yet recruiting Muscle Mass Via UltraSound in Cirrhosis (MMUSCLE) May 2, 2024 May 31, 2027
NCT05357599 Not yet recruiting N/A The Use of Endoscopic Ultrasound-Guided Portal Pressure Measurements to Guide Beta-Blocker Therapy in Patients With Compensated Cirrhosis December 2023 July 2025
NCT05744713 Not yet recruiting An Observational Study of Patients With Chronic Liver Disease May 1, 2023 December 31, 2037
NCT03946852 Not yet recruiting N/A Abdominal Regional Perfusion in Donation After Cardiac Death for Multi-Organ Transplantation June 2019 June 2026
NCT06425380 Not yet recruiting Phase 2 Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy June 2024 April 2026
NCT06458998 Not yet recruiting N/A Getting To Implementation: Improving Cancer Screening for Veterans July 15, 2024 February 28, 2030
NCT06316869 Not yet recruiting Noninvasive Prediction of Portal Hypertension in Cirrhosis Using Sound Touch Viscoelastography March 15, 2024 March 31, 2025
NCT05095714 Not yet recruiting N/A FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer. December 1, 2021 December 1, 2027
NCT06307964 Not yet recruiting Intra-Hepatic Microbiota in Alcoholic Hepatitis June 2024 July 2026
NCT06135584 Not yet recruiting N/A Study on MAFLD-related Cirrhosis Prevention and Treatment Strategies November 18, 2023 December 31, 2026
NCT06184347 Not yet recruiting Population-wide Research for HBV-related Liver Diseases in Maoming City February 2024 August 2025
NCT04053231 Not yet recruiting Hepatocarcinoma Recurrence on the Liver Study - Part2 September 2019 May 2034
NCT06288828 Not yet recruiting N/A The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients With Compensated Cirrhosis March 5, 2024 December 31, 2025
NCT05967273 Not yet recruiting N/A CirrhosisRx CDS System July 2024 June 2027
NCT05205954 Not yet recruiting N/A HepHospital: A Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease March 1, 2024 December 30, 2025
NCT06327308 Not yet recruiting Evaluation of Cirrhotic Cardiomyopathy by Cardiac MRI in Patients Waiting for Liver Transplant. March 31, 2024 December 31, 2027
NCT05538546 Not yet recruiting Baveno VI Criteria in Dynamic Monitoring of High-risk Varices in Compensated Cirrhotic Patients September 2022 December 2023
NCT04925362 Not yet recruiting N/A THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis) June 2021 June 2036
NCT05473325 Not yet recruiting Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) January 1, 2023 June 22, 2025
NCT06464952 Recruiting N/A Microbiome Modulation With Prebiotics in PTSD and Cirrhosis June 25, 2024 September 25, 2025
NCT03025074 Recruiting Blood Collection Biorepository for Liver Disease Research July 2013 December 2099
NCT03121404 Recruiting Mechanisms of Malnutrition in Cirrhosis With Portosystemic Shunting November 14, 2008 December 31, 2027
NCT03225677 Recruiting Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis July 3, 2017 September 30, 2024
NCT03472157 Recruiting N/A A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients June 20, 2018 March 2026
NCT03506893 Recruiting N/A Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic Patients July 17, 2018 December 31, 2025
NCT03625726 Recruiting N/A Rôle of the Soluble Endothelial Protein C Receptor in Cirrhosis-associated Hypercoagulability State (EXERCISE) August 3, 2018 August 2024
NCT03849235 Recruiting A Pathophysiological Study of the Postprandial Human Liver (PLS) March 2, 2019 January 1, 2025
NCT03870568 Recruiting Functional Assessment in Liver Transplantation October 6, 2015 December 2025
NCT03905746 Recruiting Study of microRNAs in a Decompensated Cirrhosis June 26, 2019 June 26, 2025
NCT04179773 Recruiting Chemotherapy and Liver Cirrhosis in Frequently-associated Cancers January 24, 2019 January 2025
NCT04371042 Recruiting PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies September 1, 2019 December 31, 2035
NCT04446832 Recruiting VACcination of LIver Transplantation Candidates July 6, 2020 July 6, 2027
NCT04490330 Recruiting Screening for Alcohol-related Cognitive Impairments in Cirrhotic Patients August 1, 2020 August 2023
NCT04620538 Recruiting Volatile Organic Compounds for the Assessment of Liver Disease April 1, 2021 September 2025
NCT04633356 Recruiting Phase 1/Phase 2 EUS Guided Portal-systemic Pressure Gradient Measurement November 12, 2020 November 11, 2024
NCT04786743 Recruiting N/A Timing of Endoscopic Intervention for Acute Variceal Hemorrhage: an RCT April 20, 2021 February 20, 2024
NCT04807803 Recruiting N/A Evaluation of Minimal Hepatic Encephalopathy in Patients With Cirrhosis and Portal Hypertension March 26, 2021 March 25, 2025
NCT04836923 Recruiting N/A LIFT Intervention in Liver Transplant Candidates October 1, 2020 September 1, 2025
NCT05027425 Recruiting Phase 2 Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant December 7, 2021 December 7, 2030
NCT05028829 Recruiting Phase 2 Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk May 10, 2023 March 1, 2031
NCT05045482 Recruiting Phase 1 Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease October 21, 2021 July 2024
NCT05064553 Recruiting ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk July 26, 2021 April 2026
NCT05140837 Recruiting Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106) December 9, 2021 December 31, 2024
NCT05147090 Recruiting Phase 4 Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B January 2, 2022 December 31, 2025
NCT05181332 Recruiting Predictive Models of Hepatic Decompensation and Survival Outcomes in Pediatric Patients With Cirrhosis January 1, 2021 December 31, 2024
NCT05201404 Recruiting Phase 3 Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis March 15, 2023 October 2025
NCT05260268 Recruiting N/A Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant December 1, 2022 January 1, 2027
NCT05463796 Recruiting InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer April 25, 2023 March 25, 2032
NCT05477277 Recruiting N/A Adverse Outcomes and Mortality in Liver Transplant November 2, 2022 July 2024
NCT05484206 Recruiting Phase 1 Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434 September 21, 2022 April 30, 2027
NCT05486572 Recruiting N/A Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI November 3, 2023 September 1, 2031
NCT05511766 Recruiting Phase 2/Phase 3 Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis November 15, 2022 January 30, 2025
NCT05541601 Recruiting Prospective Cohort for Early Detection of Liver Cancer February 23, 2022 July 2037
NCT05548452 Recruiting Phase 1/Phase 2 Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease November 21, 2022 December 2026
NCT05635266 Recruiting Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives October 26, 2021 October 2025
NCT05726032 Recruiting Phase 2 Empagliflozin in Patients With Cirrhosis and Ascites September 11, 2023 September 1, 2025
NCT05737030 Recruiting Phase 4 Effect of L-ornithine-L-aspertate (LOLA) on the Gut Microbiome February 6, 2023 December 2025
NCT05740358 Recruiting Liver Cirrhosis Network Cohort Study November 14, 2022 September 1, 2028
NCT05769868 Recruiting Phase 3 Efficacy of Esmolol in the Identification of Cardiovascular Disorders by Cirrhosis, Diabetes Mellitus and Cardiotoxic Treatments April 18, 2023 September 2027
NCT05782283 Recruiting N/A A Study to Detect Advanced Liver Disease Via AI-enabled Electrocardiogram April 18, 2023 August 2024
NCT05797649 Recruiting Comparing N-terminal-proB-type Natriuretic Peptide With Other Criteria in Pleural Fluid Analysis July 1, 2023 November 30, 2025
NCT05832229 Recruiting Phase 2 Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States October 11, 2023 November 1, 2026
NCT05998330 Recruiting N/A LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease September 20, 2023 July 2027
NCT06000748 Recruiting Phase 2/Phase 3 NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients February 1, 2024 May 1, 2024
NCT06007846 Recruiting Phase 2/Phase 3 A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer July 31, 2023 August 31, 2025
NCT06052150 Recruiting Oral Health In Cirrhosis of the Liver (ORACLE) September 18, 2023 December 31, 2024
NCT06052176 Recruiting Phase 2 Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement November 2, 2023 June 1, 2025
NCT06062108 Recruiting Prevalence of Pain in Hospitalized Cirrhotic Patients November 10, 2023 November 2024
NCT06133127 Recruiting N/A Is There an Association Between Quadriceps Strength and Different Markers of Fragility in Patients With Cirrhosis? November 20, 2023 December 2025
NCT06205992 Recruiting 3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension August 16, 2022 December 1, 2025
NCT06216509 Recruiting N/A Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements January 10, 2023 October 20, 2024
NCT06245473 Recruiting Metobolomics in the Characterisation of HE April 23, 2024 April 23, 2024
NCT06277882 Recruiting Phase 4 Efficacy and Durability of Hepatitis A Vaccination in Patients With Advanced Fibrosis and Cirrhosis February 29, 2024 May 31, 2025
NCT06306963 Recruiting Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias March 22, 2024 September 1, 2026
NCT06328517 Recruiting The Influence of Nutritional Factors on the Prognosis of Liver Cirrhosis Patients and the Exploration of Predictive Models November 1, 2023 November 1, 2026
NCT02935478 Suspended N/A Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation October 18, 2017 December 2024
NCT00287664 Suspended Phase 4 Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin vs Albumin February 2002 September 2006
NCT00511394 Suspended N/A Acute Hemodynamics of Albumin Versus Normal Saline in Cirrhosis May 2007 December 2008
NCT02271295 Suspended Phase 3 Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients July 27, 2015 July 2, 2019
NCT04940416 Terminated Eye Movement Testing for Diagnosing Encephalopathy in Patients With Liver Disease August 31, 2017 June 17, 2021
NCT02313896 Terminated N/A Cirrhosis Readmission Telehealth Project July 2014 June 2016
NCT00742339 Terminated Phase 2/Phase 3 Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome May 2005 October 2013
NCT04509336 Terminated N/A Orphenadrine Versus Baclofen in Treatment of Muscle Cramps in Cirrhotic Patients August 20, 2020 September 20, 2021
NCT00375011 Terminated Breath Test to Assess Hepatic Metabolic Reserve and to Predict Hepatic Decompensation in Cirrhotics September 2008 October 2011
NCT02026609 Terminated Glutamine Challenge as Predictor of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS) May 2013 January 27, 2015
NCT03027635 Terminated N/A PEriToneal Catheter Versus Repeated Paracentesis for Ascites in Cirrhosis January 20, 2017 May 15, 2019
NCT02457988 Terminated Early Phase 1 The Cirrhosis Outpatient Optimization, Readmission & Safety Study April 2015 March 2018
NCT00485290 Terminated N/A Effect of Meal on Portal and Esophagus Variceal Pressure June 2007 April 2008
NCT01455246 Terminated Phase 2/Phase 3 Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis October 2010 July 2014
NCT03534141 Terminated N/A Mild Hypothermia and Acute Kidney Injury in Liver Transplantation July 7, 2018 September 14, 2023
NCT00151671 Terminated Phase 2/Phase 3 Effect of a Perioperative Oral Nutritional Supplementation on Patients Undergoing Hepatic Surgery for Liver Cancer April 2003 September 2008
NCT01846819 Terminated Factors Associated With End Stage Liver Disease July 2012 December 2014
NCT01359813 Terminated Phase 3 Albumin Administration in Cirrhotic Patients With Bacterial Infection and a Systemic Inflammatory Response Syndrome Unrelated to Spontaneous Bacterial Peritonitis December 2008 June 2012
NCT00212212 Terminated N/A Selenium Supplementation of Patients With Cirrhosis March 2006 March 2012
NCT00188097 Terminated N/A Diagnosis of Variceal Bleeding and Its Control in Cirrhosis November 1999 June 2002
NCT01954524 Terminated Phase 1 A Phase 1, Open-Label Study of Intravenous Sildenafil in Patients With Cirrhosis May 2014 October 2015
NCT04264754 Terminated Characterization of Methylation Patterns in Hepatocellular Carcinoma February 13, 2018 February 1, 2021
NCT03827200 Terminated Phase 2 A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis April 11, 2019 January 21, 2021
NCT02319200 Terminated Phase 3 Primary Prevention Hepatocellular Carcinoma by Metformin June 2015 April 2016
NCT00401895 Terminated Phase 2 Transjugular Intrahepatic Portosystemic Shunt With 8- or 10-mm Covered Stents January 2006 December 2008
NCT01037959 Terminated Phase 3 Norfloxacin Therapy for Patients With Cirrhosis and Severe Liver Failure April 2010 November 2015
NCT03447730 Terminated Phase 1/Phase 2 Safety, Tolerability and Pharmacodynamics of SYNB1020 March 19, 2018 July 19, 2019
NCT01807013 Unknown status Evaluating Ultrasound, Elastometry, Minilaparoscopy and Histology for the Diagnosis of Compensated Liver Cirrhosis. February 2011 August 2016
NCT04915573 Unknown status Antimicrobial Resistance in Cirrhotic Patients June 7, 2021 September 2021
NCT01669044 Unknown status Comparison the Hemodynamics Effects Between Dexmedetomidine and Propofol in Major Abdominal Surgical Patients May 2012 December 2012
NCT01607814 Unknown status Oxidative Stress and Haemostasis Abnormalities in Cirrhosis November 2011 November 2014
NCT01530711 Unknown status Phase 4 Treatment of Hepatorenal Syndrome With Terlipressin Infusion Adjusted to Hemodynamic Response April 2012 December 2016
NCT05014594 Unknown status Phase 2 Sodium-glucose Linked Transporter 2 (SGLT-2) Inhibitors in Recurrent Ascites: a Pilot RCT September 3, 2021 May 19, 2022
NCT00004368 Unknown status Phase 1 Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis May 1990
NCT01492127 Unknown status N/A Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment December 2011 March 2016
NCT05118308 Unknown status N/A EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement November 4, 2021 December 4, 2023
NCT00742690 Unknown status Phase 2/Phase 3 Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome May 2005 March 2015
NCT00414713 Unknown status Phase 4 Transfusion Requirements in Gastrointestinal (GI) Bleeding October 2002 December 2007
NCT05157308 Unknown status A Cross Sectional Study for Determining Prevalence of Sarcopenia and Myosteatosis in Cirrhotic Patients and to Study the Association Between Imaging and Clinical Parameters March 10, 2020 December 25, 2021
NCT01350726 Unknown status Functional-three-dimensional Reconstruction of Liver by 99MTc-GSA-SPECT Scan January 2008 July 2011
NCT01350167 Unknown status N/A Screening for Liver Cancer With CT vs. Ultrasound in Patients With Advanced Liver Disease November 2001 December 2021
NCT05244005 Unknown status Extubation Failure in Critically Ill Cirrhotic Patients. February 1, 2022 January 31, 2023
NCT00163995 Unknown status Urotensin II and Vascular Tone in Cirrhosis
NCT02401490 Unknown status Phase 4 Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy April 2015 March 2018
NCT00966121 Unknown status Phase 4 Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding August 2008 July 2021
NCT03853928 Unknown status N/A Probiotics in the Prevention of Hepatocellular Carcinoma in Cirrhosis May 1, 2019 May 1, 2023
NCT00966082 Unknown status Phase 4 EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment August 2008 July 2021
NCT02256046 Unknown status N/A Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices August 2014 March 2015
NCT02238444 Unknown status Phase 4 Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy September 1, 2014 September 30, 2019
NCT02190357 Unknown status Phase 4 Rifaximin Reduces the Complications of Decompensated Cirrhosis: a Randomized Controlled Trial August 2014 August 2019
NCT02184000 Unknown status The Role of Strain Elastography in Staging Liver Fibrosis March 2014 September 2014
NCT02131831 Unknown status Telomeres Parameters in Cirrhosis June 2014 December 2015
NCT02074280 Unknown status Phase 4 Rifaximin Predicts the Complications of Decompensated Cirrhosis October 2013 December 2014
NCT04006275 Unknown status Phase 3 Comparing SonoVue With Sonazoid Using CEUS-LIRADS in HCC June 30, 2019 December 30, 2019
NCT04023136 Unknown status N/A Liver Resection Modeling July 15, 2019 May 15, 2020
NCT04057326 Unknown status N/A A Study of Oryz-Aspergillus Enzyme and Pancreatin Tablet in Patients With Cirrhosis and Malnutrition August 30, 2019 March 28, 2021
NCT04074473 Unknown status Phase 4 Impact of Nonselective Beta-blocker on Acute Kidney Injury in Cirrhotic Patients With Esophageal Varices April 13, 2015 July 30, 2020
NCT04075760 Unknown status N/A EUS-guided Combined Therapy Versus Beta Blocker Therapy in Primary Prophylaxis o GOV II and IGV I August 1, 2019 October 2020
NCT01992978 Unknown status N/A Radiofrequency-assisted Hepatectomy on the Outcomes of HCC Patients With Cirrhosis November 2013 December 2018
NCT01987791 Unknown status Observation Study of Prednisone and Cyclosporine in Treatment of Thrombocytopenia in Hepatitis B Cirrhosis January 2005
NCT04330469 Unknown status N/A Periodontal Therapy and Oral-gut-hepatic Axis Cirrhosis: a Randomized Controlled Trial March 1, 2020 December 30, 2022
NCT01948687 Unknown status Real Time Elastography in Liver Fibrosis August 2013 November 2014
NCT00005107 Unknown status Phase 1 Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia
NCT00965900 Unknown status Phase 4 Endoscopic Band Ligation (EBL) Versus Propranolol for Primary Prophylaxis of Variceal Bleeding September 2006 May 2021
NCT00906139 Unknown status Phase 4 Propofol and Fentanyl Versus Midazolam and Fentanyl for Endoscopy Sedation in Cirrhotic Patients March 2008 November 2009
NCT01863121 Unknown status Validation of Child-Turcotte-Pugh-Kumar (CTPK) Score in Predicting Short Term Mortality in Patients With Liver Cirrhosis May 2013 January 2018
NCT00343122 Unknown status Echocardiographic Assessment of Intrapulmonary Vasodilatation: Agitated Saline Versus Polygeline June 2006
NCT01820026 Unknown status Phase 4 Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis December 2012 June 2015
NCT04807023 Unknown status Decompensation of Cirrhosis and Iron Metabolism May 17, 2021 November 2022
NCT00761098 Unknown status Phase 4 Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) May 2005 August 2010
NCT03448770 Unknown status N/A To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics. August 1, 2017 July 31, 2018
NCT02755701 Unknown status Phase 4 The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites July 2016 December 2018
NCT05389280 Unknown status Impact of Acute Kidney Injury on Sarcopenia and Frailty in Patients With Liver Cirrhosis March 23, 2022 March 31, 2023
NCT02693951 Unknown status N/A Efficiency and Safety of Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices February 2016 September 2017
NCT02643212 Unknown status Phase 3 Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis May 2016 December 2019
NCT02638415 Unknown status Phase 4 The Effect of Hepatic Vein Pressure Gradient(HVPG)-Guided Therapy in Cirrhotic Patients With Esophagogastric Varices December 2015 September 2018
NCT02476695 Unknown status FibroTouch Non-invasive Evaluation of Liver Fibrosis and Cirrhosis May 2014
NCT03530657 Unknown status Assessment of Liver Fibrosis and Prognosis in Chinese Patients With CHB Infection Using STE/STQ Elastography June 4, 2018 August 1, 2021
NCT02427906 Unknown status Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients August 2014 April 2016
NCT02344823 Unknown status Phase 4 Effect of Vardenafil on Erectile Dysfunction and Portal Hemodynamics in Patients With Liver Cirrhosis June 2012
NCT03631147 Unknown status N/A The Effect of Rifaximin on Portal Vein Thrombosis September 3, 2018 December 31, 2019
NCT03676777 Unknown status Study Of Bacterial/Fungal Infections in Hospitalized Patients With Liver Cirrhosis in China November 7, 2018 February 2020
NCT03720067 Unknown status Phase 2/Phase 3 Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertension January 25, 2019 December 20, 2022
NCT03732118 Unknown status EYE-Mobile TRACKer IN the Diagnosis of Minimal Hepatic Encephalopathy December 18, 2020 October 17, 2023
NCT03743272 Unknown status Repeatability and Reproducibility of Multiparametric MRI June 3, 2017 November 1, 2022
NCT03775798 Unknown status Incidence of de Novo Hepatocellular Carcinoma After Antiviral Agents for HCV. May 1, 2016 January 1, 2021
NCT03777293 Unknown status N/A A Prospective Study to Monitor Liver Diseases Dynamically by Ultrasound Viscoelasticity January 1, 2019 January 1, 2023
NCT02272504 Unknown status A Protocol of the Canadian Prospective Study for Hepatocellular Carcinoma Surveillance Using Biomarkers August 2014 August 2020
NCT01309594 Unknown status N/A HIV Liver Regeneration Project for HIV Patients With Cirrhosis by Autologous Bone Marrow Transplantation March 2011 March 2016
NCT01212250 Unknown status N/A Carvedilol for Pre-primary Prophylaxis of Esophageal Varices in Cirrhosis September 1, 2010 December 1, 2020
NCT01205074 Unknown status Phase 2/Phase 3 ¹³C-Methacetin Breath Test (MBT) Methodology Study September 2010
NCT03123666 Unknown status N/A Recombinant Human Granulocyte Monocyte - Colony Stimulating Factor (GM CSF) for Prevention of Pneumonia in Patients With Cirrhosis April 19, 2017 October 19, 2020
NCT03085342 Unknown status N/A Evaluation of Hepatic Fibrosis on Multiparametric MRI April 4, 2017 December 2021
NCT03084185 Unknown status Evaluation of the Role of Plasma Biomarkers in the Development of Decompensation in Patients With Cirrhosis . December 2012 December 2018
NCT03069339 Unknown status N/A Carvedilol, Endoscopic Variceal Ligation or Combination of Both for Prevention of First Variceal Bleed in Child's B & C Cirrhosis March 15, 2017 November 30, 2020
NCT03195634 Unknown status WFA+M2BP in Evaluation of Portal Hypertension and Clinical Outcome in Patients With Liver Cirrhosis June 2017 December 2018
NCT01134692 Unknown status Phase 3 Probiotics for Portal Hypertension
NCT03045783 Unknown status N/A Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices December 2016 July 2019
NCT03027921 Unknown status N/A Validation in a Non-targeted Population of Single Ultrasound Doppler Signs of Liver Fibrosis February 2017
NCT03277651 Unknown status Noninvasive Diagnostic Platform for Liver Fibrosis and Portal Hypertension October 9, 2017 December 31, 2020
NCT03023189 Unknown status Phase 4 Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding April 3, 2017 April 2020
NCT02983968 Unknown status Use of the French Healthcare Insurance Database September 2016 October 2018
NCT03311152 Unknown status N/A Circulating Cell-free DNA-based Epigenetic Biomarker mSEPT9 for Hepatocellular Carcinoma Detection in Cirrhosis February 12, 2018 February 12, 2023
NCT02964195 Unknown status N/A Efficacy of Rifaximin in Treatment of Cirrhotic Gastroesophageal Variceal Bleeding November 2016 April 2018
NCT03363412 Unknown status N/A Tips Underdilatation in Patients With Cirrhosis June 1, 2010 December 30, 2021
NCT02931812 Unknown status Feeding Behavior and Taste Sensitivity Before and After Liver or Renal Transplantation May 2014 December 2022
NCT02925975 Unknown status Phase 4 Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPS January 2015 June 2020
NCT02854241 Unknown status N/A Comparison of Biannual Ultrasonography and Annual Unenhanced Magnetic Resonance Imaging for HCC Surveillance July 1, 2016 June 2022
NCT02757170 Unknown status Phase 4 Assessment of Coagulation Abnormalities in Acute on Chronic Liver Failure Patients Using Thromboelastography July 2015 July 2016
NCT01331785 Withdrawn N/A Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis April 2011 July 2012
NCT04048707 Withdrawn Phase 2 Angiotensin 2 for Hepatorenal Syndrome July 1, 2021 July 1, 2023
NCT00760032 Withdrawn Phase 4 Lipopolysaccharide Binding Protein and Development of Infectious Events in Cirrhotic Patients
NCT02275585 Withdrawn Portal Vein Thrombosis in Cirrhosis October 2013 October 2014
NCT02465619 Withdrawn To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis. June 2017
NCT03908255 Withdrawn Phase 2 Branched-chain Amino Acid Supplementation for Hepatocellular Carcinoma June 1, 2021 December 30, 2023
NCT03433508 Withdrawn N/A Restrictive Versus Liberal Red Blood Cell Transfusion in Patients of Cirrhosis With Septic Shock December 15, 2018 February 15, 2019
NCT02837939 Withdrawn Phase 2/Phase 3 Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction July 2016 July 2025
NCT02824354 Withdrawn Phase 3 Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. December 1, 2018 December 1, 2022
NCT01882855 Withdrawn Effect of Music on Attention and Prospective Memory in Hepatic Encephalopathy December 2012 March 2016
NCT01777971 Withdrawn The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis July 2012 October 2014
NCT01923376 Withdrawn N/A Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) February 2013 February 2014
NCT02258048 Withdrawn The Use of Transient Elastography to Predict Clinical Decompensation in Patients With Early Cirrhosis October 2014 October 2015
NCT05051293 Withdrawn Comparison of the Concentration of Estrogen and Testosterone Ratio in Male Patients With Cirrhosis and Hypotension August 22, 2021 August 17, 2024
NCT01956864 Withdrawn Phase 1 Study of High-Dose Oral Vitamin D for the Prevention of Liver Cancer September 2013 February 11, 2016
NCT02356250 Withdrawn A Pilot Study: Defining Peripheral Endothelial Function in Portal Hypertensive Cirrhotic Patients February 18, 2015 November 29, 2016
NCT00603200 Withdrawn Effect of Large Volume Paracentesis on Fatigue in Cirrhosis January 2008 December 2009
NCT01801228 Withdrawn Phase 2 Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis; a Study of Efficacy and Side Effects February 2013 October 2015
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0001394
MedGen concept unique identifier (MedGen Concept name)
C1623038
MedGen unique identifier (MedGen Concept name)
351476