Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL10 MUTATION
IL10 MUTATION - Associated Disease
- arteriosclerosis
- Source Database
- DisGeNET
- Description
- Atorvastatin treatment increased the percentage and inhibitory ability of nTregs, decreased serum IFN-γ and hsCRP levels, and decreased IL-10 and TGF-β1 levels, as compared with the non-atorvastatin group.Our findings suggest that nTregs play an atheroprotective role in atherosclerosis.
- Pubmed
- 25740578
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00589577631564597
Drugs