Hyperalgesia
Information
- Disease name
- Hyperalgesia
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT00833755 | Completed | N/A | Effect of Ketamine on Opioid-Induced Hyperalgesia | September 2008 | April 2016 |
| NCT00001956 | Completed | Phase 2 | Influence of Genetics in Pain Sensitivity | January 2000 | February 2005 |
| NCT02011477 | Completed | Early Phase 1 | Hypoalgesic Effects Neural Mobilization Techniques | March 2013 | November 2013 |
| NCT02025686 | Completed | N/A | Hyperbaric Oxygen Therapy Attenuates Central Sensitization Induced by a Thermal Injury in Human Volunteers (HBO) | March 2012 | October 2012 |
| NCT02243254 | Completed | N/A | Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen | July 2014 | |
| NCT02253966 | Completed | Phase 2 | Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty | October 2014 | March 2016 |
| NCT02596360 | Completed | Phase 1 | Dextromethorphan Effect on Central Sensitization to Pain in Healthy Volunteers | November 2015 | March 2016 |
| NCT02653703 | Completed | N/A | L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain | October 2014 | December 2014 |
| NCT02938455 | Completed | DNA Methylation and Perioperative Pain Treatment | October 2016 | May 2020 | |
| NCT02976337 | Completed | Phase 2 | Effect of High-dose Naloxone Following Third Molar Extraction | October 12, 2017 | December 27, 2023 |
| NCT02992938 | Completed | Phase 4 | Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia | December 2016 | September 28, 2018 |
| NCT03217942 | Completed | Early Phase 1 | Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model | July 1, 2017 | October 1, 2017 |
| NCT03354624 | Completed | N/A | Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity | November 26, 2017 | February 28, 2018 |
| NCT03450161 | Completed | Phase 4 | Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting | May 14, 2018 | January 9, 2021 |
| NCT03470038 | Completed | Early Phase 1 | Interaction Between NGF and Acute Exercise-induced Ischemia | March 15, 2018 | June 15, 2018 |
| NCT03793790 | Completed | N/A | The Role of Learning in Nocebo Hyperalgesia | September 20, 2018 | April 30, 2019 |
| NCT03826615 | Completed | N/A | Gabapentin Pretreatment for Staged Bilateral Cataract Operations | February 1, 2019 | January 3, 2020 |
| NCT03985995 | Completed | N/A | Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults | September 16, 2019 | December 23, 2019 |
| NCT04059978 | Completed | N/A | Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults | May 26, 2020 | October 15, 2020 |
| NCT04197154 | Completed | N/A | Pain-related Fear as a Facilitator of Nocebo Hyperalgesia | October 14, 2019 | February 14, 2020 |
| NCT04199858 | Completed | N/A | Electrophysiological Correlates of Nocebo Effects on Pain | October 21, 2019 | January 7, 2020 |
| NCT04387097 | Completed | Drip-infusion of Remifentanil for RIH | May 1, 2018 | July 22, 2019 | |
| NCT04902547 | Completed | N/A | Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy | May 1, 2021 | January 5, 2024 |
| NCT05284383 | Completed | N/A | Reducing Nocebo Effects on Pressure Pain | March 23, 2021 | April 5, 2022 |
| NCT05483647 | Completed | N/A | ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY | January 1, 2021 | July 5, 2022 |
| NCT00218374 | Completed | N/A | Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia | October 2006 | June 2007 |
| NCT00241579 | Completed | Phase 1/Phase 2 | Analgesic Efficacy of Smoked Cannabis | February 2002 | January 2004 |
| NCT00260325 | Completed | Phase 4 | Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers | August 2004 | April 2006 |
| NCT00279032 | Completed | Phase 1 | GW406381 In Patients With Peripheral Nerve Injury | September 2003 | |
| NCT00373893 | Completed | Phase 1 | Effects of Lidocaine Patch on Intradermal Capsaicin Induced Pain and Hyperalgesia | December 2005 | February 2006 |
| NCT00387413 | Completed | Phase 1 | A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers | October 2, 2006 | May 31, 2007 |
| NCT00413257 | Completed | Phase 2/Phase 3 | Effects of Nefopam on Hyperalgesia After Cardiac Surgery | December 2006 | November 2008 |
| NCT00701909 | Completed | Phase 3 | Pain Medicine for Wound Care Procedures | June 2008 | April 2009 |
| NCT00825422 | Completed | Phase 3 | Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar Surgery | January 2009 | August 2010 |
| NCT00832546 | Completed | Phase 1 | A Safety Tolerance and Experimental Hyperalgesia Study of Oral NGX426 in Healthy Male Voluneteers | May 2008 | September 2008 |
| NCT00001307 | Completed | Positron Emission Tomography to Measure Pain and Pain Control | August 1992 | August 2005 | |
| NCT00991809 | Completed | N/A | Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil | February 2009 | May 2010 |
| NCT01025245 | Completed | Phase 4 | Effect of Intraoperative Magnesium on Remifentanil-induced Postoperative Hyperalgesia After Thyroidectomy | November 2009 | January 2010 |
| NCT01222091 | Completed | Phase 2 | Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids | February 2009 | June 2011 |
| NCT01301079 | Completed | Phase 3 | Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia | September 2010 | September 2012 |
| NCT01544062 | Completed | Phase 4 | IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery | July 2012 | August 2014 |
| NCT01581450 | Completed | Phase 1 | Hyperalgesia and Pain | January 2012 | April 2012 |
| NCT01594047 | Completed | N/A | Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone | December 1, 2009 | August 1, 2014 |
| NCT01702389 | Completed | Phase 4 | Opioid-induced Hyperalgesia After Remifentanil Infusion | October 2012 | December 2012 |
| NCT01918475 | Completed | N/A | Analgesic Effect of Oxytocin Receptor Modulation | July 2013 | December 2014 |
| NCT01935206 | Completed | Phase 1 | Effect of High Dose Naloxone on Secondary Hyperalgesia | June 2013 | November 2013 |
| NCT01981395 | Completed | Phase 1 | Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers | January 2014 | April 2016 |
| NCT01992146 | Completed | Phase 2 | Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair. | November 11, 2015 | May 11, 2018 |
| NCT04834427 | Enrolling by invitation | Phase 4 | Safety and Efficacy Evaluation of S (+) - Ketamine in Children | April 20, 2022 | December 4, 2024 |
| NCT04697498 | Recruiting | N/A | Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations | December 16, 2020 | December 2025 |
| NCT05357157 | Recruiting | Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fibromyalgia | May 31, 2022 | December 1, 2026 | |
| NCT03066739 | Recruiting | Phase 2 | Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia | February 25, 2023 | December 31, 2024 |
| NCT05603702 | Recruiting | Phase 1 | STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis | March 17, 2023 | December 31, 2024 |
| NCT04576507 | Suspended | Phase 1 | Repeated Cannabis Administration on Experimental Pain and Abuse Liability | June 1, 2021 | December 31, 2025 |
| NCT04596644 | Suspended | Phase 2 | Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans | August 1, 2021 | August 31, 2025 |
| NCT00802048 | Terminated | Phase 3 | Local Anesthetic Infusion and Sternotomy | February 2009 | August 2010 |
| NCT01615510 | Terminated | Phase 1 | Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models | October 2012 | March 2013 |
| NCT01015482 | Unknown status | Phase 4 | The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun) | November 2009 | April 2010 |
| NCT01189721 | Unknown status | Phase 4 | Effect of Propofol on Remifentanil-induced Postoperative Hyperalgesia in Patients Undergoing Thyroid Surgery | August 2010 | July 2011 |
| NCT01480765 | Unknown status | Phase 4 | Preventing Pain After Heart Surgery | November 2011 | December 2013 |
| NCT02934763 | Unknown status | Phase 4 | Opioid Induced Hyperalgesia (OIH) Modulation With Propranolol | October 2016 | May 2017 |
| NCT03844243 | Unknown status | Early Phase 1 | Exercise-induced Ischemia and the Influence of Pain Modulation in a Nerve Growth Factor (NGF) Model | February 18, 2019 | June 30, 2019 |
| NCT00789386 | Unknown status | Phase 4 | The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers | November 2008 | December 2009 |
| NCT00811837 | Unknown status | Phase 4 | The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers | January 2009 | September 2009 |
| NCT03164161 | Unknown status | N/A | The Relationship Between Saliva β-endorphins Levels, Cold Pressor Test and Perception of Pain in Oral Surgery Procedures | May 2017 | December 2017 |
| NCT03225690 | Unknown status | Phase 4 | Prevention of Hyperalgesia With Epidural Morphine | July 19, 2017 | December 1, 2018 |
| NCT00886106 | Unknown status | Phase 4 | The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers | June 2009 | March 2010 |
| NCT02127853 | Unknown status | Phase 4 | Effect of Gabapentin on Pain of the Second Cataract Surgery | July 2014 | February 2016 |
| NCT00188383 | Unknown status | Phase 1/Phase 2 | Effects of N-Methyl-D-Aspartate (NMDA)-Receptor Antagonism on Hyperalgesia, Opioid Use, and Pain After Radical Prostatectomy | January 2004 | December 2006 |
| NCT04220697 | Unknown status | N/A | Central Sensitisation and Postoperative Pain | January 29, 2020 | December 31, 2022 |
| NCT02689713 | Withdrawn | Phase 2 | Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent | June 15, 2018 | November 14, 2018 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0031005
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006930