aortic valve insufficiency
Information
- Disease name
- aortic valve insufficiency
- Disease ID
- DOID:57
- Description
- "An aortic valve disease that is characterized by leaking of the aortic valve of the heart causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle." [url:http\://en.wikipedia.org/wiki/Aortic_insufficiency]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04281771 | Active, not recruiting | N/A | Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI | September 17, 2019 | October 28, 2026 |
| NCT04415047 | Active, not recruiting | N/A | The JenaValve ALIGN-AR Pivotal Trial | May 22, 2020 | August 2028 |
| NCT06192706 | Active, not recruiting | N/A | Clinical Investigation for the Foldax Tria Aortic Heart Valve- India | January 1, 2022 | September 1, 2024 |
| NCT01757665 | Active, not recruiting | N/A | ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE) | December 11, 2012 | August 2026 |
| NCT03876964 | Available | J-Valve Compassionate Use | |||
| NCT05742789 | Completed | Phase 1 | Effect of Anesthetics on Troponin I and С-reactive Protein | November 30, 2021 | January 9, 2023 |
| NCT05696509 | Completed | Phase 3 | Influence of Anesthetics on Clinical Outcome in Mitral and Aortic Valve Replacement in Adults | January 3, 2020 | October 16, 2022 |
| NCT05695287 | Completed | Phase 1 | The Effects of Sevoflurane, Isoflurane and Propofol During Cardiac Surgery | January 22, 2021 | December 16, 2022 |
| NCT00636987 | Completed | N/A | Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra | April 2007 | March 2016 |
| NCT00727181 | Completed | N/A | An Observational, Prospective Evaluation of the Trifecta™ Valve | November 2007 | December 2010 |
| NCT01092442 | Completed | CryoValve SG Pulmonary Human Heart Valve Post Clearance Study | January 2010 | December 2014 | |
| NCT01157572 | Completed | Phase 4 | Effect of Beta Blockade on Left Ventricular Remodeling and Function in Moderate to Severe Asymptomatic Aortic Regurgitation | August 2010 | September 2014 |
| NCT04802200 | Completed | Short-term Clinical Follow-up of the Vascular Closure Device MANTATM in Minimally Invasive Cardiac Surgery | March 17, 2021 | December 31, 2021 | |
| NCT01171625 | Completed | N/A | Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX | October 2007 | September 2018 |
| NCT01236469 | Completed | CryoValve® SG Aortic Human Heart Valve Combination Study | June 2010 | February 2012 | |
| NCT01334801 | Completed | Biomarkers in Aortic Stenosis - B.A.S.S. | July 2010 | January 31, 2020 | |
| NCT01593917 | Completed | Trifecta™ Long Term Follow-Up (LTFU) Study | July 2, 2012 | September 26, 2019 | |
| NCT01651052 | Completed | N/A | Clinical Trial of the Edwards Aortic Bioprosthesis, Model 11000 | July 2011 | July 2018 |
| NCT01720342 | Completed | Enable® Aortic Sutureless Bioprosthesis Evaluation | February 2013 | April 2018 | |
| NCT01787604 | Completed | N/A | Study of Aortic Root Reimplantation Procedure | January 2011 | November 20, 2015 |
| NCT00001314 | Completed | Investigation of Heart Function in Patients With Heart Valve Defects | May 1992 | March 2001 | |
| NCT03807921 | Completed | Phase 4 | Anticoagulation for Aortic Bioprosthesis (ANTIPRO) | January 1, 2019 | December 31, 2019 |
| NCT02815514 | Completed | German TAVI-Register | January 2009 | December 2016 | |
| NCT03644784 | Completed | Protocoled Quantitative Assessment of Aortic Regurgitation Using Videodensitometry in a Multicontinental Trial in Rotterdam, Montreal, Yamaguchi, Segeberg, Amsterdam. | September 1, 2017 | March 31, 2019 | |
| NCT00082121 | Completed | Phase 2 | Safety and Efficacy of TP10, a Complement Inhibitor, in Adult Women Undergoing Cardiopulmonary Bypass Surgery | April 2004 | December 2005 |
| NCT00475267 | Completed | N/A | Aortic Valve Replacement With Trifecta(TM) | May 2007 | January 2012 |
| NCT00475709 | Completed | N/A | Aortic Valve Replacement With Trifecta(TM) | June 2007 | January 2012 |
| NCT00478803 | Completed | Phase 3 | Conservative Aortic Valve Surgery for Aortic Insufficiency and Aneurysms of the Aortic Root. CAVIAAR | May 2007 | November 2014 |
| NCT04035356 | Enrolling by invitation | HAART Annuloplasty Device Valve Repair Registry | September 22, 2020 | July 2035 | |
| NCT05714293 | Enrolling by invitation | N/A | CT-evaluation of Coronary Ostia Height After Surgical Aortic Valve Replacement. | January 11, 2023 | January 10, 2025 |
| NCT05927090 | Enrolling by invitation | Outcomes of Type A Aortic Dissection Repair | January 1, 2005 | December 30, 2024 | |
| NCT05389865 | Not yet recruiting | Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes | August 2023 | August 2024 | |
| NCT05572710 | Recruiting | Avalus European Registry - an Observational Study to Evaluate Safety and Efficacy in a Real World Population | June 10, 2020 | December 31, 2025 | |
| NCT03826264 | Recruiting | Transpacific TAVR Registry | June 15, 2019 | December 31, 2031 | |
| NCT03728049 | Recruiting | N/A | Von Willebrand Factor Point-of-care Testing to Improve Minimally Invasive TAVI Outcomes | December 18, 2019 | December 2025 |
| NCT06295068 | Recruiting | Evaluation of ARi With OpSens SavvyWire | November 30, 2023 | April 30, 2024 | |
| NCT05902897 | Recruiting | Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis | January 1, 2023 | October 30, 2023 | |
| NCT04149600 | Recruiting | Identification of Genetic Causes of Calcific Aortic Valve Disease | September 25, 2018 | June 30, 2027 | |
| NCT04162444 | Recruiting | Results of the Aortic Valve Reconstruction in Children | February 18, 2020 | October 2027 | |
| NCT06034028 | Recruiting | N/A | J-Valve TF Early Feasibility Study | October 16, 2023 | June 25, 2029 |
| NCT05892588 | Recruiting | Prevalence Study of Cardiovascular Diseases in a Population ≥ 65 Years in Italy | June 1, 2022 | July 1, 2023 | |
| NCT06235385 | Recruiting | European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study | February 7, 2024 | August 1, 2029 | |
| NCT05172973 | Recruiting | N/A | ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves | November 22, 2023 | February 2034 |
| NCT05295628 | Recruiting | N/A | Evaluation of Safety and Effectiveness of the EMBLOK EPS During TAVR | October 17, 2023 | February 1, 2025 |
| NCT05212597 | Recruiting | Phase 2 | Open Label RCT for Chronic Severe AR : Entresto vs. CCB/ARB | January 12, 2022 | December 2024 |
| NCT03578952 | Terminated | N/A | Evaluation of Effectiveness and Safety of Evolut R Valve In Patients With Pure Aortic Regurgitation | August 10, 2018 | February 21, 2019 |
| NCT02351726 | Terminated | N/A | Mitroflow DL Post Approval Study- North America | March 2015 | December 31, 2019 |
| NCT01636648 | Terminated | Enable I Long-term Follow-up Study | August 2012 | April 2016 | |
| NCT00598767 | Terminated | Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space | June 2003 | July 2008 | |
| NCT00598598 | Terminated | Echocardiographic Assessment of Cardiovascular Changes in Long Term Space Flight | October 2003 | July 2008 | |
| NCT01165827 | Unknown status | German Aortic Valve Registry | July 2010 | December 2022 | |
| NCT02713932 | Unknown status | The Italian Society of Invasive Cardiology Registry on Percutaneous Aortic Valve | July 2010 | ||
| NCT01201070 | Unknown status | Phase 4 | Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery | September 2009 | November 2011 |
| NCT04047082 | Unknown status | Online Videodensitometric Assessment of Aortic Regurgitation in the Cath-Lab | May 15, 2019 | September 2019 | |
| NCT02288871 | Unknown status | N/A | Pilot Trial: Comparison of Flow Patterns | October 2014 | December 2021 |
| NCT02623907 | Unknown status | China Valve Registry Study-1 | May 2016 | May 2020 | |
| NCT00173186 | Unknown status | Aortic Regurgitation After Surgical Repair of Outlet-Type Ventricular Septal Defect | January 1987 | February 2005 | |
| NCT03361046 | Unknown status | Polish Transcatheter Aortic Valve-in-Valve Implantation (ViV-TAVI) Registry | January 1, 2018 | May 30, 2024 | |
| NCT00598754 | Withdrawn | Diagnostic Three Dimensional Echocardiography Study Protocol | June 2001 | July 2008 |
- Disase is a (Disease Ontology)
- DOID:62
- Cross Reference ID (Disease Ontology)
- ICD10CM:I06.1
- Cross Reference ID (Disease Ontology)
- ICD9CM:395.1
- Cross Reference ID (Disease Ontology)
- ICD9CM:396.3
- Cross Reference ID (Disease Ontology)
- MESH:D001022
- Cross Reference ID (Disease Ontology)
- NCI:C51223
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:155283004
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:194736003
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:60234000
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0003504
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0155568
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0264774
- Exact Synonym (Disease Ontology)
- aortic incompetence
- Exact Synonym (Disease Ontology)
- aortic insufficiency
- Exact Synonym (Disease Ontology)
- aortic regurgitation
- Exact Synonym (Disease Ontology)
- Rheumatic aortic insufficiency
- Exact Synonym (Disease Ontology)
- Rheumatic aortic regurgitation
- Exact Synonym (Disease Ontology)
- rheumatic aortic valve insufficiency
- Exact Synonym (Disease Ontology)
- Rheumatic aortic valve regurgitation
- Disase Synonym (Disease Ontology)
- Corrigan's disease
- MeSH unique ID (MeSH (Medical Subject Headings))
- D001022